GREMLIN Database
YBAT - Inner membrane transport protein YbaT
UniProt: P77400 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13248
Length: 430 (407)
Sequences: 24613 (15821)
Seq/√Len: 784.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
322_W326_T4.2851.00
316_L327_W4.1741.00
143_T333_V4.1291.00
54_G238_T3.2861.00
224_V228_R3.0171.00
319_K327_W3.0131.00
323_R326_T2.8731.00
14_G220_K2.8631.00
219_V225_I2.8311.00
361_L392_I2.7201.00
78_I310_E2.7031.00
95_S307_M2.6511.00
308_G318_N2.6281.00
221_D224_V2.6241.00
175_G247_V2.6151.00
19_V232_V2.5921.00
316_L319_K2.4951.00
322_W325_S2.4781.00
173_I177_W2.4291.00
136_L337_M2.4281.00
276_V280_I2.3611.00
15_L232_V2.3401.00
217_D309_S2.3021.00
218_K302_N2.2291.00
66_R371_R2.2191.00
186_V189_P2.2061.00
267_Q270_S2.2061.00
389_L393_V2.2021.00
82_R91_S2.1971.00
85_L369_R2.1821.00
135_A340_T2.1771.00
305_D309_S2.1761.00
144_L148_L2.1591.00
15_L19_V2.1491.00
15_L225_I2.1351.00
18_V219_V2.0871.00
151_H155_R2.0781.00
256_E271_P2.0261.00
228_R232_V2.0111.00
140_A337_M1.9961.00
63_A364_F1.9811.00
364_F391_V1.9641.00
162_G166_M1.9581.00
311_R315_K1.9501.00
330_I334_V1.9341.00
14_G17_N1.9331.00
82_R87_N1.9291.00
38_A46_T1.9151.00
384_G388_M1.9071.00
19_V236_V1.9021.00
9_G320_S1.8951.00
55_I59_F1.8931.00
143_T329_N1.8681.00
419_I423_V1.8481.00
253_S256_E1.8101.00
393_V397_Y1.8091.00
85_L365_V1.7891.00
221_D225_I1.7551.00
81_F94_L1.7431.00
413_S417_S1.7371.00
96_L417_S1.7291.00
17_N158_V1.7261.00
267_Q271_P1.7261.00
146_N294_N1.7221.00
317_M331_I1.7061.00
231_L235_G1.7021.00
99_L332_V1.6641.00
180_Q183_H1.6631.00
49_A198_C1.6631.00
140_A333_V1.6621.00
22_G233_A1.6571.00
94_L362_A1.6521.00
411_I415_L1.6391.00
45_S195_F1.6371.00
110_A293_I1.6361.00
130_L133_L1.6161.00
13_L17_N1.6071.00
166_M170_L1.5961.00
321_L325_S1.5821.00
386_L390_L1.5791.00
117_A134_Y1.5581.00
147_S330_I1.5571.00
55_I390_L1.5491.00
418_L422_M1.5301.00
106_I336_I1.5291.00
129_H133_L1.5251.00
369_R372_H1.5201.00
136_L340_T1.5201.00
235_G239_L1.5101.00
215_A298_F1.5051.00
167_I284_G1.5001.00
383_V387_V1.5001.00
86_G90_F1.4951.00
110_A139_I1.4861.00
397_Y401_S1.4721.00
61_G234_I1.4531.00
139_I336_I1.4471.00
327_W331_I1.4381.00
305_D320_S1.4371.00
9_G305_D1.4321.00
113_F138_I1.4321.00
165_M169_L1.4261.00
221_D228_R1.4221.00
85_L90_F1.4191.00
315_K318_N1.4141.00
365_V369_R1.4081.00
176_V247_V1.4071.00
279_V283_I1.4041.00
222_P227_P1.4041.00
403_G406_A1.3921.00
270_S278_Y1.3881.00
136_L140_A1.3861.00
315_K319_K1.3811.00
74_N217_D1.3761.00
53_G202_T1.3761.00
17_N154_G1.3661.00
81_F362_A1.3651.00
56_V394_G1.3601.00
179_L250_S1.3541.00
261_A267_Q1.3461.00
270_S275_H1.3441.00
139_I333_V1.3401.00
61_G230_F1.3291.00
374_I378_L1.3211.00
71_Y83_R1.3141.00
225_I228_R1.3081.00
113_F286_L1.2991.00
13_L18_V1.2961.00
60_S364_F1.2931.00
388_M392_I1.2851.00
16_W20_S1.2841.00
62_Y231_L1.2821.00
59_F390_L1.2771.00
405_R408_I1.2741.00
385_T389_L1.2731.00
373_D376_A1.2651.00
239_L243_S1.2621.00
304_M328_G1.2611.00
321_L324_Q1.2601.00
143_T330_I1.2591.00
172_I243_S1.2551.00
70_S378_L1.2521.00
175_G251_D1.2521.00
109_V292_A1.2491.00
142_M293_I1.2461.00
273_L277_G1.2441.00
395_F398_S1.2401.00
408_I411_I1.2331.00
13_L154_G1.2301.00
304_M313_L1.2271.00
15_L228_R1.2251.00
26_M237_T1.2221.00
84_G366_V1.2171.00
79_D83_R1.2071.00
407_L411_I1.2031.00
47_W246_L1.2011.00
132_L136_L1.1951.00
171_L175_G1.1881.00
404_S408_I1.1791.00
327_W330_I1.1731.00
374_I377_S1.1721.00
33_A112_A1.1621.00
64_Y77_I1.1581.00
391_V395_F1.1571.00
387_V401_S1.1561.00
22_G212_M1.1561.00
301_F329_N1.1561.00
383_V388_M1.1521.00
66_R69_A1.1511.00
23_I236_V1.1241.00
148_L323_R1.1231.00
145_F156_L1.1231.00
12_P220_K1.1221.00
18_V229_A1.1221.00
375_H378_L1.1211.00
92_L96_L1.1191.00
396_I400_W1.1181.00
412_G416_L1.1161.00
420_V423_V1.1141.00
73_S79_D1.1121.00
68_G80_F1.1101.00
220_K225_I1.1081.00
170_L174_A1.1031.00
99_L304_M1.1011.00
191_S194_A1.1001.00
300_V332_V1.0981.00
10_N324_Q1.0981.00
157_E294_N1.0951.00
81_F90_F1.0901.00
412_G415_L1.0881.00
21_I215_A1.0851.00
417_S420_V1.0831.00
383_V386_L1.0771.00
404_S407_L1.0771.00
392_I396_I1.0721.00
45_S188_A1.0701.00
386_L389_L1.0671.00
143_T147_S1.0651.00
63_A388_M1.0641.00
365_V392_I1.0611.00
309_S318_N1.0591.00
78_I306_N1.0491.00
117_A286_L1.0481.00
133_L137_G1.0371.00
408_I412_G1.0371.00
39_A46_T1.0351.00
147_S321_L1.0331.00
405_R409_W1.0321.00
156_L160_L1.0321.00
114_G134_Y1.0301.00
169_L173_I1.0291.00
140_A144_L1.0221.00
117_A121_L1.0211.00
137_G141_V1.0171.00
73_S83_R1.0131.00
136_L341_A1.0001.00
368_I389_L0.9911.00
155_R159_I0.9891.00
388_M401_S0.9831.00
23_I237_T0.9811.00
387_V391_V0.9781.00
51_A242_I0.9771.00
253_S271_P0.9771.00
187_S190_P0.9761.00
388_M402_Q0.9711.00
70_S376_A0.9701.00
171_L269_A0.9681.00
261_A264_A0.9661.00
207_A356_F0.9631.00
399_L402_Q0.9601.00
150_N298_F0.9581.00
160_L291_S0.9521.00
361_L396_I0.9511.00
210_G214_N0.9471.00
410_I414_L0.9471.00
417_S421_A0.9461.00
320_S324_Q0.9461.00
391_V394_G0.9401.00
165_M240_L0.9391.00
172_I247_V0.9381.00
96_L313_L0.9331.00
192_S195_F0.9311.00
9_G218_K0.9311.00
395_F399_L0.9311.00
361_L365_V0.9301.00
385_T388_M0.9291.00
141_V290_A0.9291.00
108_M349_A0.9261.00
367_A388_M0.9231.00
75_G78_I0.9211.00
216_A226_M0.9161.00
384_G387_V0.9111.00
354_A410_I0.9091.00
114_G135_A0.9081.00
388_M395_F0.9071.00
172_I176_V0.9071.00
12_P151_H0.9061.00
27_V30_G0.9051.00
238_T242_I0.9051.00
47_W249_L0.9031.00
186_V190_P0.8981.00
20_S158_V0.8981.00
246_L250_S0.8951.00
83_R373_D0.8911.00
142_M294_N0.8851.00
9_G302_N0.8851.00
75_G79_D0.8811.00
337_M340_T0.8791.00
382_I386_L0.8791.00
17_N155_R0.8691.00
351_V355_T0.8671.00
232_V236_V0.8671.00
373_D377_S0.8651.00
409_W412_G0.8641.00
54_G206_Y0.8621.00
371_R374_I0.8621.00
394_G401_S0.8551.00
382_I388_M0.8531.00
113_F289_T0.8521.00
415_L419_I0.8521.00
108_M204_L0.8511.00
334_V338_L0.8471.00
82_R310_E0.8451.00
197_S201_I0.8451.00
317_M327_W0.8431.00
118_V131_I0.8431.00
196_F397_Y0.8431.00
192_S196_F0.8401.00
407_L410_I0.8391.00
51_A55_I0.8391.00
114_G131_I0.8381.00
313_L317_M0.8361.00
69_A379_P0.8311.00
164_K288_A0.8301.00
155_R158_V0.8291.00
251_D268_A0.8281.00
403_G407_L0.8281.00
16_W158_V0.8271.00
147_S325_S0.8241.00
70_S379_P0.8231.00
376_A379_P0.8191.00
382_I387_V0.8181.00
90_F362_A0.8171.00
113_F290_A0.8141.00
388_M394_G0.8131.00
372_H375_H0.8131.00
48_V195_F0.8111.00
67_L367_A0.8061.00
134_Y137_G0.8031.00
144_L147_S0.8011.00
211_M299_A0.8011.00
368_I372_H0.7981.00
274_G277_G0.7981.00
263_T267_Q0.7981.00
15_L229_A0.7961.00
368_I388_M0.7931.00
333_V337_M0.7931.00
383_V402_Q0.7881.00
384_G389_L0.7861.00
297_L333_V0.7811.00
58_M62_Y0.7801.00
221_D227_P0.7771.00
416_L420_V0.7761.00
58_M231_L0.7761.00
207_A360_Y0.7741.00
142_M297_L0.7731.00
148_L152_A0.7701.00
184_I250_S0.7681.00
81_F366_V0.7671.00
59_F63_A0.7661.00
413_S420_V0.7621.00
12_P150_N0.7611.00
397_Y400_W0.7601.00
382_I385_T0.7591.00
406_A410_I0.7591.00
188_A195_F0.7581.00
390_L401_S0.7581.00
176_V243_S0.7581.00
329_N332_V0.7561.00
98_Y102_L0.7561.00
378_L381_L0.7531.00
19_V229_A0.7531.00
48_V51_A0.7461.00
408_I413_S0.7451.00
344_N347_S0.7401.00
179_L247_V0.7381.00
16_W155_R0.7351.00
111_R348_L0.7321.00
304_M331_I0.7311.00
154_G158_V0.7301.00
146_N298_F0.7301.00
24_G161_V0.7291.00
394_G398_S0.7241.00
84_G369_R0.7221.00
406_A409_W0.7191.00
416_L419_I0.7181.00
227_P230_F0.7161.00
302_N305_D0.7161.00
26_M233_A0.7161.00
31_I244_L0.7151.00
60_S395_F0.7121.00
25_A295_A0.7041.00
67_L80_F0.7031.00
101_T356_F0.7011.00
48_V52_F0.7001.00
132_L135_A0.7001.00
388_M391_V0.7001.00
329_N336_I0.6981.00
27_V164_K0.6951.00
316_L331_I0.6951.00
78_I82_R0.6891.00
44_A249_L0.6891.00
368_I385_T0.6871.00
370_L374_I0.6851.00
74_N305_D0.6851.00
107_A348_L0.6841.00
194_A197_S0.6831.00
392_I395_F0.6811.00
331_I335_L0.6801.00
38_A42_M0.6791.00
9_G12_P0.6781.00
172_I244_L0.6741.00
391_V402_Q0.6731.00
57_A209_F0.6731.00
102_L296_N0.6711.00
394_G397_Y0.6701.00
275_H279_V0.6701.00
244_L265_V0.6681.00
47_W51_A0.6661.00
419_I422_M0.6661.00
70_S374_I0.6661.00
236_V240_L0.6641.00
174_A274_G0.6631.00
276_V279_V0.6611.00
116_Y285_A0.6591.00
105_S352_A0.6581.00
85_L366_V0.6511.00
19_V22_G0.6511.00
152_A155_R0.6511.00
138_I293_I0.6501.00
308_G317_M0.6501.00
103_A335_L0.6491.00
78_I95_S0.6491.00
114_G117_A0.6481.00
97_L101_T0.6481.00
27_V240_L0.6461.00
174_A178_S0.6461.00
414_L418_L0.6451.00
297_L301_F0.6451.00
413_S421_A0.6441.00
182_A185_S0.6441.00
259_K262_D0.6431.00
410_I413_S0.6401.00
64_Y363_V0.6391.00
409_W413_S0.6391.00
217_D305_D0.6381.00
16_W19_V0.6361.00
411_I414_L0.6361.00
104_V351_V0.6361.00
367_A371_R0.6351.00
147_S329_N0.6351.00
393_V396_I0.6341.00
301_F328_G0.6341.00
243_S247_V0.6341.00
140_A143_T0.6331.00
373_D378_L0.6331.00
41_L197_S0.6331.00
390_L394_G0.6321.00
146_N329_N0.6321.00
264_A269_A0.6291.00
46_T245_A0.6281.00
97_L359_C0.6261.00
154_G294_N0.6251.00
142_M290_A0.6221.00
61_G209_F0.6221.00
413_S416_L0.6221.00
247_V250_S0.6211.00
47_W242_I0.6211.00
384_G401_S0.6191.00
407_L413_S0.6181.00
50_F205_A0.6171.00
66_R382_I0.6171.00
109_V293_I0.6151.00
163_I167_I0.6141.00
117_A138_I0.6131.00
12_P16_W0.6121.00
355_T359_C0.6111.00
68_G226_M0.6111.00
139_I340_T0.6101.00
364_F392_I0.6101.00
219_V226_M0.6091.00
269_A273_L0.6081.00
22_G26_M0.6071.00
328_G331_I0.6061.00
132_L340_T0.6041.00
384_G391_V0.6041.00
68_G213_A0.6031.00
25_A296_N0.6031.00
236_V239_L0.6011.00
403_G408_I0.6011.00
110_A114_G0.6011.00
103_A332_V0.6001.00
411_I420_V0.5981.00
398_S401_S0.5981.00
214_N299_A0.5971.00
37_Q346_G0.5961.00
152_A156_L0.5961.00
338_L341_A0.5951.00
361_L395_F0.5951.00
66_R380_I0.5941.00
120_F283_I0.5931.00
163_I284_G0.5931.00
232_V235_G0.5901.00
410_I415_L0.5901.00
183_H186_V0.5891.00
411_I417_S0.5881.00
62_Y382_I0.5871.00
244_L248_L0.5861.00
65_A69_A0.5861.00
120_F282_V0.5851.00
319_K322_W0.5851.00
346_G349_A0.5851.00
404_S411_I0.5841.00
105_S108_M0.5841.00
184_I249_L0.5841.00
52_F199_I0.5821.00
180_Q184_I0.5801.00
119_Q282_V0.5791.00
283_I287_L0.5771.00
77_I214_N0.5761.00
222_P225_I0.5761.00
412_G419_I0.5761.00
14_G151_H0.5741.00
35_L245_A0.5741.00
399_L407_L0.5711.00
392_I399_L0.5701.00
141_V145_F0.5701.00
288_A291_S0.5701.00
213_A230_F0.5701.00
340_T343_L0.5691.00
398_S402_Q0.5691.00
140_A330_I0.5681.00
372_H385_T0.5661.00
385_T402_Q0.5661.00
78_I91_S0.5651.00
77_I210_G0.5651.00
42_M49_A0.5651.00
251_D272_L0.5651.00
150_N215_A0.5641.00
158_V162_G0.5641.00
53_G206_Y0.5631.00
334_V337_M0.5631.00
329_N333_V0.5621.00
395_F402_Q0.5611.00
370_L378_L0.5601.00
61_G65_A0.5591.00
34_L349_A0.5581.00
109_V112_A0.5571.00
248_L265_V0.5561.00
207_A210_G0.5561.00
406_A413_S0.5551.00
412_G417_S0.5551.00
316_L320_S0.5541.00
382_I401_S0.5511.00
28_G241_Y0.5511.00
302_N320_S0.5481.00
143_T297_L0.5461.00
149_S152_A0.5461.00
226_M230_F0.5441.00
81_F91_S0.5441.00
9_G74_N0.5441.00
44_A47_W0.5421.00
67_L84_G0.5421.00
384_G392_I0.5411.00
115_A131_I0.5411.00
84_G370_L0.5411.00
25_A211_M0.5411.00
153_V298_F0.5401.00
224_V227_P0.5391.00
405_R410_I0.5391.00
35_L39_A0.5391.00
59_F387_V0.5391.00
300_V304_M0.5361.00
101_T355_T0.5361.00
391_V401_S0.5341.00
236_V243_S0.5341.00
259_K263_T0.5331.00
66_R70_S0.5331.00
388_M399_L0.5321.00
157_E164_K0.5321.00
161_V164_K0.5321.00
99_L103_A0.5321.00
410_I417_S0.5311.00
31_I34_L0.5311.00
31_I168_L0.5301.00
207_A352_A0.5301.00
107_A339_M0.5291.00
38_A198_C0.5281.00
37_Q41_L0.5261.00
193_G196_F0.5241.00
37_Q40_L0.5231.00
356_F359_C0.5231.00
139_I337_M0.5201.00
205_A241_Y0.5201.00
382_I394_G0.5201.00
418_L421_A0.5201.00
185_S188_A0.5201.00
138_I290_A0.5191.00
280_I284_G0.5181.00
269_A277_G0.5181.00
387_V394_G0.5181.00
31_I35_L0.5181.00
396_I399_L0.5151.00
414_L417_S0.5151.00
159_I162_G0.5141.00
60_S210_G0.5141.00
403_G413_S0.5131.00
179_L251_D0.5131.00
392_I401_S0.5121.00
174_A273_L0.5111.00
210_G360_Y0.5111.00
47_W50_F0.5101.00
137_G140_A0.5101.00
264_A268_A0.5091.00
110_A142_M0.5091.00
91_S95_S0.5091.00
65_A230_F0.5081.00
167_I280_I0.5081.00
23_I161_V0.5081.00
175_G179_L0.5071.00
13_L150_N0.5071.00
131_I135_A0.5071.00
304_M308_G0.5071.00
94_L359_C0.5071.00
86_G91_S0.5061.00
411_I422_M0.5061.00
218_K320_S0.5061.00
390_L393_V0.5051.00
375_H381_L0.5051.00
45_S187_S0.5051.00
166_M169_L0.5041.00
371_R384_G0.5041.00
20_S161_V0.5041.00
163_I287_L0.5041.00
106_I293_I0.5021.00
219_V229_A0.5021.00
366_V370_L0.5011.00
212_M226_M0.5011.00
53_G203_F0.5001.00
138_I142_M0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l1lA 2 0.9488 100 0.252 Contact Map
3giaA 1 0.9721 100 0.286 Contact Map
4djkA 2 0.9302 100 0.332 Contact Map
2jlnA 1 0.9163 98.5 0.869 Contact Map
3dh4A 3 0.9186 98.4 0.874 Contact Map
2xq2A 2 0.914 98.2 0.88 Contact Map
4wgvA 2 0.8186 97.5 0.897 Contact Map
4xp4A 1 0.9488 96.8 0.908 Contact Map
4us3A 1 0.8814 96.6 0.91 Contact Map
2a65A 2 0.9488 96.5 0.911 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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