GREMLIN Database
YBBN - Uncharacterized protein YbbN
UniProt: P77395 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13261
Length: 284 (276)
Sequences: 1132 (836)
Seq/√Len: 50.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
62_D65_A7.3691.00
129_N132_D5.5681.00
231_R234_E5.2341.00
212_N215_D3.8091.00
163_R166_D3.3061.00
168_E172_K3.2431.00
217_A221_Q3.2261.00
9_I59_A3.1001.00
51_Q103_R2.9041.00
33_E62_D2.6711.00
187_V190_I2.6471.00
188_A191_E2.3881.00
241_G245_K2.3861.00
101_A104_A2.3241.00
187_V191_E2.3091.00
206_Q210_A2.2601.00
35_S38_C2.1571.00
17_V20_Q2.1481.00
195_Q200_P2.1371.00
29_Y35_S2.1221.00
34_R37_H2.0911.00
208_Q215_D2.0771.00
47_S99_E2.0701.00
185_G188_A1.9520.99
29_Y34_R1.9390.99
130_Y157_T1.9340.99
81_V93_F1.9010.99
16_Q20_Q1.8650.99
32_S35_S1.8550.99
274_K278_Q1.8060.99
181_T184_Q1.7930.99
223_A239_L1.7780.99
44_I102_I1.7710.99
120_Q124_L1.7440.99
248_T252_G1.7350.99
47_S51_Q1.7340.99
250_A253_Q1.7190.99
119_Q123_Q1.6860.98
32_S37_H1.6810.98
137_L153_L1.6430.98
196_A199_T1.6410.98
16_Q19_E1.6070.98
33_E65_A1.5980.98
179_Q188_A1.5960.98
29_Y37_H1.5960.98
195_Q199_T1.5660.97
104_A107_D1.5520.97
63_C78_I1.5500.97
37_H43_P1.5490.97
29_Y60_K1.5270.97
99_E103_R1.5020.97
24_T57_I1.4940.97
11_E68_M1.4940.97
144_S147_N1.4930.97
184_Q188_A1.4920.97
123_Q127_E1.4850.96
198_D201_E1.4650.96
83_L109_V1.4600.96
35_S43_P1.4530.96
82_Y92_G1.4460.96
219_A238_L1.4420.96
216_A242_H1.4390.96
186_L190_I1.4380.96
181_T185_G1.4370.96
252_G255_R1.4340.96
9_I61_L1.4290.96
38_C43_P1.4070.95
67_Q71_A1.4060.95
74_G82_Y1.3950.95
220_T242_H1.3770.95
209_V216_A1.3660.94
32_S43_P1.3640.94
233_E274_K1.3590.94
214_E245_K1.3570.94
197_A201_E1.3510.94
34_R43_P1.3510.94
204_Q208_Q1.3310.93
182_R190_I1.3310.93
35_S39_L1.3290.93
195_Q198_D1.2940.92
34_R39_L1.2920.92
33_E78_I1.2810.92
181_T190_I1.2630.92
241_G244_R1.2510.91
29_Y32_S1.2330.91
134_L154_L1.2330.91
196_A200_P1.2320.90
22_M86_N1.2310.90
97_Q101_A1.2240.90
44_I99_E1.2240.90
29_Y38_C1.2180.90
185_G190_I1.2100.90
184_Q190_I1.2030.89
25_P54_G1.1980.89
125_M157_T1.1870.89
49_A56_F1.1850.89
243_L252_G1.1820.89
32_S64_D1.1730.88
121_A137_L1.1730.88
187_V192_L1.1500.87
68_M71_A1.1470.87
258_F262_L1.1470.87
194_K198_D1.1470.87
46_E60_K1.1440.87
34_R38_C1.1330.86
179_Q191_E1.1290.86
185_G191_E1.1250.86
227_H261_I1.1190.86
205_L222_L1.1170.86
193_L197_A1.1120.85
215_D218_L1.1080.85
75_L82_Y1.1020.85
125_M130_Y1.0970.85
15_Q19_E1.0910.84
216_A219_A1.0890.84
29_Y39_L1.0820.84
186_L192_L1.0720.83
96_P102_I1.0690.83
188_A192_L1.0680.83
236_L275_Y1.0580.82
183_Y190_I1.0570.82
11_E69_I1.0560.82
158_L166_D1.0470.82
268_G272_A1.0460.82
53_N102_I1.0430.81
182_R187_V1.0390.81
236_L271_L1.0390.81
193_L200_P1.0380.81
232_N265_L1.0320.81
48_L103_R1.0220.80
205_L209_V1.0070.79
120_Q123_Q1.0070.79
52_Y107_D1.0060.79
125_M160_A1.0040.79
182_R188_A1.0020.79
24_T54_G1.0020.79
182_R189_Q1.0000.79
226_L238_L0.9990.78
181_T189_Q0.9950.78
29_Y43_P0.9940.78
181_T188_A0.9910.78
179_Q182_R0.9860.78
124_L136_L0.9810.77
124_L132_D0.9690.76
196_A201_E0.9610.76
195_Q201_E0.9560.75
181_T186_L0.9550.75
183_Y188_A0.9510.75
231_R248_T0.9470.75
118_A153_L0.9430.74
63_C80_T0.9370.74
91_D108_K0.9360.74
193_L196_A0.9330.74
265_L269_D0.9300.73
40_Q44_I0.9290.73
252_G256_K0.9270.73
8_N60_K0.9270.73
181_T191_E0.9240.73
197_A200_P0.9230.73
243_L282_L0.9230.73
82_Y89_P0.9160.72
182_R191_E0.9140.72
213_P222_L0.9130.72
83_L105_L0.9120.72
219_A241_G0.9120.72
36_Q43_P0.9110.72
166_D169_A0.9090.72
194_K199_T0.9080.72
182_R186_L0.9040.71
193_L198_D0.9040.71
31_W62_D0.9010.71
48_L56_F0.8970.71
188_A196_A0.8940.70
166_D170_V0.8890.70
184_Q187_V0.8890.70
35_S60_K0.8890.70
180_D190_I0.8860.70
227_H232_N0.8840.69
174_I177_Q0.8840.69
9_I13_N0.8840.69
75_L109_V0.8810.69
48_L106_L0.8740.69
184_Q192_L0.8730.68
41_L81_V0.8720.68
134_L161_L0.8700.68
203_Q206_Q0.8650.68
97_Q105_L0.8610.67
181_T192_L0.8610.67
32_S39_L0.8600.67
207_Q210_A0.8590.67
112_R115_E0.8590.67
194_K197_A0.8570.67
27_L83_L0.8540.67
183_Y191_E0.8540.67
141_W150_I0.8540.67
188_A193_L0.8490.66
63_C75_L0.8420.66
232_N261_I0.8410.66
206_Q226_L0.8380.65
261_I265_L0.8370.65
20_Q23_T0.8360.65
268_G271_L0.8360.65
32_S46_E0.8350.65
189_Q192_L0.8340.65
20_Q24_T0.8310.65
135_P139_D0.8300.65
233_E237_E0.8290.64
206_Q238_L0.8270.64
217_A250_A0.8240.64
138_K158_L0.8220.64
183_Y187_V0.8130.63
236_L265_L0.8120.63
41_L93_F0.8080.62
145_N170_V0.8050.62
77_A92_G0.7990.62
27_L74_G0.7930.61
9_I16_Q0.7890.61
34_R64_D0.7860.60
117_K139_D0.7810.60
148_G151_G0.7760.59
48_L51_Q0.7750.59
273_S281_A0.7710.59
266_G272_A0.7660.58
122_M137_L0.7650.58
198_D202_I0.7640.58
269_D273_S0.7600.58
249_A254_T0.7580.58
185_G189_Q0.7580.58
62_D75_L0.7560.57
114_E140_A0.7470.56
37_H60_K0.7420.56
116_L119_Q0.7410.56
91_D105_L0.7370.55
243_L255_R0.7330.55
9_I66_E0.7290.55
182_R192_L0.7260.54
55_Q107_D0.7230.54
181_T187_V0.7220.54
175_P179_Q0.7220.54
10_N66_E0.7210.54
261_I272_A0.7200.54
36_Q39_L0.7200.54
55_Q110_L0.7190.54
265_L271_L0.7150.53
243_L247_L0.7120.53
243_L279_L0.7120.53
179_Q185_G0.7110.53
128_S133_A0.7110.53
93_F97_Q0.7040.52
38_C64_D0.7030.52
121_A128_S0.7020.52
159_I171_L0.7010.52
52_Y106_L0.7010.52
261_I271_L0.7000.52
174_I178_D0.6980.51
206_Q222_L0.6950.51
180_D183_Y0.6880.50
39_L43_P0.6870.50
101_A108_K0.6870.50
266_G269_D0.6840.50
226_L234_E0.6830.50
19_E22_M0.6820.50
25_P83_L0.6820.50
131_T135_P0.6820.50
183_Y186_L0.6810.50
155_A171_L0.6800.50
31_W35_S0.6800.50
28_F31_W0.6800.50
56_F106_L0.6770.49
75_L92_G0.6770.49
42_T78_I0.6760.49
186_L189_Q0.6740.49
271_L275_Y0.6730.49
192_L200_P0.6720.49
248_T255_R0.6680.48
131_T158_L0.6680.48
61_L66_E0.6680.48
141_W151_G0.6640.48
176_L179_Q0.6620.48
30_F61_L0.6590.47
84_F89_P0.6560.47
159_I212_N0.6550.47
47_S103_R0.6550.47
181_T193_L0.6540.47
202_I206_Q0.6530.47
168_E193_L0.6510.47
42_T58_L0.6470.46
242_H252_G0.6460.46
189_Q193_L0.6450.46
120_Q139_D0.6450.46
180_D188_A0.6410.46
62_D128_S0.6390.45
187_V193_L0.6390.45
29_Y96_P0.6360.45
243_L266_G0.6360.45
48_L52_Y0.6340.45
89_P92_G0.6320.45
118_A140_A0.6300.44
184_Q191_E0.6290.44
151_G173_T0.6260.44
193_L201_E0.6250.44
44_I48_L0.6220.44
151_G174_I0.6200.43
21_S26_V0.6200.43
192_L195_Q0.6150.43
68_M72_Q0.6140.43
209_V219_A0.6090.42
140_A150_I0.6090.42
14_L34_R0.6070.42
180_D184_Q0.6050.42
13_N16_Q0.6050.42
277_R281_A0.6040.42
206_Q231_R0.6040.42
41_L102_I0.6030.42
37_H77_A0.6020.42
52_Y56_F0.6020.42
29_Y42_T0.6020.42
35_S96_P0.6010.42
102_I108_K0.6010.42
182_R185_G0.5960.41
39_L46_E0.5950.41
253_Q257_T0.5930.41
220_T254_T0.5910.41
61_L70_A0.5900.40
155_A170_V0.5890.40
189_Q195_Q0.5870.40
23_T82_Y0.5870.40
169_A173_T0.5860.40
188_A194_K0.5850.40
267_T272_A0.5830.40
223_A235_A0.5830.40
180_D191_E0.5830.40
61_L82_Y0.5820.40
159_I164_S0.5810.40
10_N13_N0.5750.39
43_P60_K0.5710.39
201_E204_Q0.5710.39
93_F102_I0.5700.38
93_F105_L0.5700.38
216_A245_K0.5690.38
270_A278_Q0.5690.38
31_W37_H0.5680.38
147_N235_A0.5670.38
182_R193_L0.5670.38
39_L60_K0.5660.38
247_L255_R0.5640.38
115_E147_N0.5640.38
138_K166_D0.5620.38
121_A136_L0.5610.38
14_L43_P0.5600.37
191_E196_A0.5580.37
242_H249_A0.5580.37
61_L260_E0.5560.37
32_S36_Q0.5510.37
14_L32_S0.5510.37
78_I156_E0.5470.36
28_F32_S0.5470.36
54_G93_F0.5460.36
216_A241_G0.5450.36
191_E195_Q0.5440.36
222_L238_L0.5440.36
76_R103_R0.5440.36
114_E147_N0.5430.36
41_L77_A0.5420.36
120_Q136_L0.5400.36
146_Q194_K0.5390.35
34_R60_K0.5380.35
232_N269_D0.5370.35
69_I77_A0.5370.35
184_Q197_A0.5360.35
118_A137_L0.5360.35
176_L182_R0.5350.35
80_T94_Q0.5330.35
179_Q184_Q0.5330.35
193_L199_T0.5320.35
195_Q203_Q0.5310.35
259_Q278_Q0.5300.35
38_C81_V0.5280.34
29_Y77_A0.5270.34
139_D143_L0.5270.34
63_C272_A0.5260.34
262_L272_A0.5260.34
33_E39_L0.5250.34
180_D185_G0.5230.34
27_L106_L0.5230.34
204_Q209_V0.5230.34
29_Y41_L0.5200.34
232_N236_L0.5190.34
206_Q224_L0.5190.34
44_I47_S0.5190.34
22_M88_Q0.5180.34
43_P77_A0.5180.34
233_E236_L0.5170.33
31_W43_P0.5160.33
38_C76_R0.5160.33
240_F258_F0.5150.33
179_Q186_L0.5120.33
33_E80_T0.5120.33
208_Q218_L0.5110.33
44_I113_E0.5100.33
199_T202_I0.5090.33
117_K143_L0.5090.33
12_S23_T0.5090.33
61_L80_T0.5080.33
37_H96_P0.5080.33
14_L19_E0.5070.33
179_Q190_I0.5050.32
55_Q112_R0.5040.32
18_L101_A0.5040.32
191_E198_D0.5030.32
63_C94_Q0.5020.32
222_L226_L0.5020.32
247_L262_L0.5010.32
184_Q189_Q0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qouA 1 0.9648 100 0.323 Contact Map
2qc7A 2 0.6866 99.9 0.657 Contact Map
2c0gA 1 0.6831 99.9 0.669 Contact Map
3bj5A 1 0.4261 99.9 0.669 Contact Map
3apqA 1 0.4049 99.9 0.672 Contact Map
3apoA 1 0.3908 99.9 0.676 Contact Map
2yzuA 1 0.3662 99.9 0.676 Contact Map
2qgvA 2 0.3838 99.9 0.677 Contact Map
4xhmA 1 0.3803 99.9 0.681 Contact Map
1thxA 1 0.3803 99.9 0.682 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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