WZXC - ECOLI - GREMLIN Contacts

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WZXC - Lipopolysaccharide biosynthesis protein WzxC

UniProt:	P77377	Sequences: MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLLTVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGIVVCVAVFLLSDLIGDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTCTVVSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTADSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQDDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWNSIIPVLQLLCVVGLLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMAGAIGVTLGFLLVQIINTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYALGIVLKGQLALGMLLAVQIATGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13576
Length:	492 (451)
Sequences:	17345 (14928)
Seq/√Len:	702.9

ECOLI - WZXC MURJ RFBX WZXE YGHQ
BACSU - TUAB EPSK YABM YTGP SP5B YKVU
HALSA - Q9HRT3 Q9HSW2 Q9HQQ5
SULSO - Q97XT3 Q7LXE2 Q97XG2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
278_D	281_K	4.939	1.00
140_E	143_K	3.317	1.00
207_A	211_R	3.266	1.00
98_L	101_L	3.211	1.00
324_I	328_Q	3.067	1.00
352_R	355_I	3.011	1.00
45_T	247_N	2.907	1.00
416_L	420_L	2.862	1.00
354_D	358_K	2.811	1.00
305_M	328_Q	2.778	1.00
139_L	274_K	2.702	1.00
309_N	313_P	2.411	1.00
363_K	394_N	2.323	1.00
308_S	324_I	2.318	1.00
239_G	242_V	2.283	1.00
329_L	381_I	2.243	1.00
336_L	392_I	2.216	1.00
230_S	246_Y	2.184	1.00
308_S	328_Q	2.165	1.00
326_V	380_A	2.145	1.00
417_S	420_L	2.140	1.00
370_A	386_G	2.127	1.00
218_A	357_F	2.125	1.00
245_G	322_S	2.106	1.00
431_V	459_A	2.104	1.00
284_V	288_K	2.076	1.00
275_I	281_K	2.066	1.00
112_A	116_K	2.061	1.00
230_S	371_I	2.054	1.00
96_F	116_K	2.054	1.00
359_F	397_L	2.022	1.00
234_L	238_L	2.002	1.00
303_G	307_V	2.000	1.00
13_W	142_N	1.995	1.00
329_L	388_L	1.971	1.00
428_T	432_S	1.945	1.00
168_L	171_T	1.939	1.00
238_L	242_V	1.926	1.00
37_D	40_Q	1.914	1.00
310_N	313_P	1.907	1.00
69_R	212_F	1.882	1.00
279_T	283_R	1.850	1.00
203_L	207_A	1.836	1.00
303_G	453_I	1.817	1.00
307_V	310_N	1.815	1.00
34_R	317_G	1.809	1.00
233_V	375_G	1.788	1.00
374_G	386_G	1.779	1.00
46_V	235_A	1.763	1.00
378_A	385_L	1.740	1.00
375_G	383_V	1.730	1.00
100_D	112_A	1.715	1.00
309_N	324_I	1.710	1.00
297_N	338_S	1.696	1.00
325_P	381_I	1.679	1.00
286_F	346_L	1.678	1.00
222_I	361_V	1.670	1.00
238_L	380_A	1.668	1.00
76_E	80_L	1.665	1.00
74_H	78_T	1.660	1.00
142_N	146_M	1.655	1.00
233_V	371_I	1.654	1.00
373_I	376_Q	1.654	1.00
302_L	429_L	1.653	1.00
366_L	393_I	1.641	1.00
432_S	456_G	1.631	1.00
281_K	284_V	1.624	1.00
396_I	400_F	1.615	1.00
301_L	335_L	1.614	1.00
428_T	456_G	1.609	1.00
371_I	375_G	1.607	1.00
44_L	48_L	1.606	1.00
99_S	116_K	1.598	1.00
336_L	395_T	1.595	1.00
427_P	463_M	1.584	1.00
134_L	138_E	1.571	1.00
382_G	386_G	1.566	1.00
326_V	384_T	1.562	1.00
283_R	287_Y	1.558	1.00
318_E	321_N	1.556	1.00
379_G	382_G	1.556	1.00
312_V	323_I	1.555	1.00
139_L	271_A	1.550	1.00
329_L	385_L	1.530	1.00
75_L	79_T	1.530	1.00
457_V	461_V	1.529	1.00
230_S	387_F	1.529	1.00
325_P	328_Q	1.522	1.00
304_L	331_C	1.520	1.00
309_N	328_Q	1.517	1.00
312_V	327_L	1.515	1.00
281_K	285_N	1.511	1.00
298_F	425_S	1.510	1.00
329_L	384_T	1.507	1.00
155_G	179_N	1.500	1.00
372_V	376_Q	1.498	1.00
140_E	194_I	1.495	1.00
234_L	383_V	1.486	1.00
412_R	416_L	1.486	1.00
253_A	330_L	1.484	1.00
73_S	76_E	1.482	1.00
333_V	388_L	1.477	1.00
424_L	463_M	1.468	1.00
272_F	282_L	1.455	1.00
369_P	373_I	1.450	1.00
374_G	378_A	1.450	1.00
47_S	118_L	1.445	1.00
167_P	171_T	1.444	1.00
282_L	346_L	1.443	1.00
287_Y	291_S	1.440	1.00
373_I	377_M	1.430	1.00
429_L	433_Y	1.430	1.00
386_G	390_V	1.424	1.00
242_V	380_A	1.424	1.00
33_A	248_L	1.416	1.00
215_W	357_F	1.410	1.00
20_I	149_T	1.410	1.00
171_T	175_G	1.408	1.00
95_V	119_S	1.405	1.00
307_V	311_F	1.402	1.00
269_F	273_A	1.393	1.00
358_K	362_F	1.391	1.00
114_L	173_I	1.388	1.00
367_F	371_I	1.375	1.00
352_R	406_V	1.371	1.00
234_L	243_A	1.361	1.00
249_A	323_I	1.352	1.00
158_C	175_G	1.337	1.00
70_K	73_S	1.336	1.00
202_S	205_S	1.336	1.00
322_S	325_P	1.323	1.00
275_I	285_N	1.321	1.00
19_V	23_G	1.314	1.00
359_F	401_V	1.312	1.00
160_V	164_H	1.312	1.00
229_L	368_I	1.311	1.00
65_S	212_F	1.310	1.00
268_L	289_L	1.303	1.00
233_V	372_V	1.302	1.00
303_G	428_T	1.298	1.00
279_T	350_K	1.294	1.00
154_A	182_V	1.290	1.00
29_M	251_N	1.282	1.00
434_A	437_I	1.270	1.00
228_N	231_T	1.269	1.00
280_E	284_V	1.268	1.00
249_A	326_V	1.267	1.00
381_I	384_T	1.257	1.00
30_T	34_R	1.256	1.00
65_S	69_R	1.251	1.00
38_N	245_G	1.250	1.00
28_Q	156_F	1.249	1.00
26_L	30_T	1.242	1.00
239_G	243_A	1.241	1.00
72_I	75_L	1.237	1.00
131_F	188_G	1.231	1.00
434_A	438_V	1.226	1.00
147_I	186_L	1.224	1.00
233_V	237_I	1.223	1.00
286_F	343_I	1.213	1.00
436_G	452_Q	1.212	1.00
147_I	187_F	1.211	1.00
333_V	384_T	1.206	1.00
123_V	126_P	1.205	1.00
312_V	324_I	1.203	1.00
374_G	377_M	1.201	1.00
359_F	398_S	1.197	1.00
45_T	244_G	1.196	1.00
403_I	406_V	1.196	1.00
17_A	145_G	1.194	1.00
40_Q	43_L	1.192	1.00
78_T	82_W	1.191	1.00
222_I	364_T	1.189	1.00
378_A	382_G	1.188	1.00
96_F	100_D	1.179	1.00
157_T	161_V	1.178	1.00
304_L	327_L	1.175	1.00
59_D	63_A	1.172	1.00
366_L	370_A	1.170	1.00
77_L	134_L	1.170	1.00
245_G	323_I	1.167	1.00
294_G	298_F	1.166	1.00
332_V	388_L	1.166	1.00
317_G	320_W	1.162	1.00
21_I	152_V	1.161	1.00
215_W	354_D	1.159	1.00
248_L	316_F	1.158	1.00
371_I	374_G	1.156	1.00
367_F	387_F	1.151	1.00
371_I	387_F	1.147	1.00
222_I	357_F	1.144	1.00
424_L	428_T	1.144	1.00
188_G	192_R	1.144	1.00
425_S	429_L	1.143	1.00
326_V	381_I	1.141	1.00
272_F	349_A	1.137	1.00
100_D	104_D	1.135	1.00
214_A	218_A	1.132	1.00
124_V	181_A	1.131	1.00
343_I	399_Y	1.131	1.00
33_A	316_F	1.130	1.00
82_W	86_G	1.124	1.00
212_F	353_V	1.124	1.00
38_N	319_K	1.122	1.00
433_Y	437_I	1.120	1.00
219_D	356_S	1.119	1.00
185_L	189_Y	1.118	1.00
52_A	56_T	1.115	1.00
367_F	390_V	1.115	1.00
175_G	179_N	1.110	1.00
370_A	374_G	1.106	1.00
23_G	27_V	1.101	1.00
241_G	245_G	1.101	1.00
41_F	45_T	1.101	1.00
301_L	305_M	1.100	1.00
430_V	434_A	1.098	1.00
14_S	267_V	1.092	1.00
120_L	177_L	1.086	1.00
75_L	202_S	1.083	1.00
86_G	90_V	1.079	1.00
141_F	267_V	1.076	1.00
44_L	172_A	1.073	1.00
271_A	274_K	1.071	1.00
321_N	324_I	1.063	1.00
158_C	162_S	1.059	1.00
365_F	369_P	1.059	1.00
310_N	436_G	1.059	1.00
280_E	283_R	1.058	1.00
225_L	364_T	1.057	1.00
143_K	190_F	1.055	1.00
234_L	246_Y	1.053	1.00
308_S	327_L	1.052	1.00
358_K	361_V	1.052	1.00
100_D	116_K	1.048	1.00
361_V	365_F	1.048	1.00
208_P	351_A	1.045	1.00
450_A	454_A	1.043	1.00
69_R	208_P	1.042	1.00
237_I	375_G	1.041	1.00
67_I	133_A	1.039	1.00
83_L	206_V	1.038	1.00
210_L	213_G	1.032	1.00
101_L	104_D	1.030	1.00
174_L	178_V	1.028	1.00
38_N	244_G	1.027	1.00
400_F	404_K	1.024	1.00
448_L	452_Q	1.021	1.00
120_L	123_V	1.018	1.00
6_K	9_S	1.017	1.00
226_N	367_F	1.007	1.00
343_I	398_S	1.004	1.00
339_V	395_T	1.000	1.00
24_L	156_F	0.994	1.00
249_A	330_L	0.993	1.00
89_I	93_V	0.989	1.00
176_Y	180_S	0.988	1.00
230_S	367_F	0.984	1.00
124_V	184_T	0.981	1.00
103_G	111_L	0.981	1.00
433_Y	436_G	0.980	1.00
311_F	315_V	0.980	1.00
43_L	240_A	0.978	1.00
11_A	267_V	0.977	1.00
92_C	95_V	0.976	1.00
113_P	116_K	0.974	1.00
32_L	172_A	0.972	1.00
453_I	457_V	0.970	1.00
170_M	173_I	0.970	1.00
385_L	389_L	0.969	1.00
29_M	316_F	0.969	1.00
68_Q	351_A	0.968	1.00
31_V	35_I	0.965	1.00
234_L	380_A	0.965	1.00
305_M	308_S	0.965	1.00
313_P	321_N	0.964	1.00
159_T	175_G	0.963	1.00
306_V	429_L	0.963	1.00
282_L	350_K	0.962	1.00
94_A	98_L	0.959	1.00
37_D	320_W	0.958	1.00
189_Y	193_K	0.957	1.00
158_C	178_V	0.955	1.00
79_T	83_L	0.952	1.00
18_T	22_I	0.948	1.00
35_I	164_H	0.947	1.00
99_S	112_A	0.946	1.00
46_V	243_A	0.946	1.00
310_N	452_Q	0.944	1.00
161_V	164_H	0.943	1.00
92_C	96_F	0.943	1.00
397_L	400_F	0.939	1.00
65_S	213_G	0.937	1.00
328_Q	332_V	0.937	1.00
330_L	384_T	0.937	1.00
205_S	208_P	0.935	1.00
186_L	190_F	0.931	1.00
65_S	209_N	0.930	1.00
299_P	460_F	0.928	1.00
355_I	401_V	0.925	1.00
35_I	163_A	0.923	1.00
275_I	278_D	0.923	1.00
333_V	336_L	0.921	1.00
244_G	248_L	0.920	1.00
135_M	191_G	0.915	1.00
312_V	316_F	0.914	1.00
116_K	120_L	0.913	1.00
314_L	449_L	0.912	1.00
271_A	275_I	0.911	1.00
37_D	319_K	0.910	1.00
388_L	391_Q	0.909	1.00
348_M	356_S	0.907	1.00
253_A	334_G	0.905	1.00
79_T	206_V	0.898	1.00
11_A	264_I	0.896	1.00
323_I	326_V	0.891	1.00
47_S	114_L	0.890	1.00
249_A	327_L	0.890	1.00
425_S	428_T	0.885	1.00
267_V	270_P	0.884	1.00
307_V	452_Q	0.883	1.00
80_L	209_N	0.878	1.00
113_P	170_M	0.877	1.00
86_G	89_I	0.876	1.00
24_L	28_Q	0.874	1.00
30_T	316_F	0.871	1.00
393_I	397_L	0.870	1.00
14_S	145_G	0.867	1.00
204_A	207_A	0.864	1.00
305_M	332_V	0.863	1.00
321_N	325_P	0.863	1.00
319_K	322_S	0.861	1.00
302_L	425_S	0.860	1.00
81_Y	84_N	0.860	1.00
347_L	401_V	0.850	1.00
215_W	353_V	0.849	1.00
210_L	214_A	0.849	1.00
314_L	446_G	0.847	1.00
15_A	263_I	0.846	1.00
107_N	110_D	0.846	1.00
67_I	137_K	0.845	1.00
179_N	183_R	0.842	1.00
10_G	139_L	0.840	1.00
246_Y	330_L	0.840	1.00
244_G	247_N	0.838	1.00
435_L	455_T	0.838	1.00
49_V	231_T	0.837	1.00
250_Y	254_V	0.836	1.00
77_L	80_L	0.835	1.00
251_N	255_V	0.834	1.00
101_L	105_V	0.834	1.00
99_S	103_G	0.833	1.00
368_I	372_V	0.830	1.00
11_A	15_A	0.829	1.00
97_L	101_L	0.829	1.00
385_L	388_L	0.829	1.00
30_T	33_A	0.827	1.00
357_F	361_V	0.826	1.00
305_M	309_N	0.821	1.00
415_I	419_W	0.821	1.00
162_S	167_P	0.819	1.00
370_A	389_L	0.818	1.00
8_I	12_K	0.818	1.00
293_V	338_S	0.816	1.00
97_L	100_D	0.816	1.00
247_N	251_N	0.810	1.00
9_S	142_N	0.809	1.00
174_L	177_L	0.809	1.00
13_W	17_A	0.808	1.00
103_G	112_A	0.808	1.00
333_V	387_F	0.808	1.00
36_I	40_Q	0.806	1.00
119_S	123_V	0.802	1.00
216_L	353_V	0.802	1.00
211_R	214_A	0.802	1.00
68_Q	353_V	0.799	1.00
81_Y	131_F	0.797	1.00
165_F	168_L	0.795	1.00
355_I	358_K	0.793	1.00
397_L	401_V	0.791	1.00
221_I	225_L	0.789	1.00
232_L	236_R	0.788	1.00
12_K	16_I	0.788	1.00
7_T	11_A	0.788	1.00
48_L	52_A	0.786	1.00
88_G	92_C	0.786	1.00
237_I	376_Q	0.786	1.00
235_A	243_A	0.785	1.00
121_A	180_S	0.783	1.00
70_K	74_H	0.780	1.00
222_I	360_N	0.780	1.00
79_T	82_W	0.777	1.00
437_I	441_G	0.776	1.00
85_V	89_I	0.773	1.00
177_L	180_S	0.771	1.00
381_I	385_L	0.770	1.00
83_L	87_L	0.769	1.00
345_S	349_A	0.768	1.00
75_L	78_T	0.767	1.00
248_L	251_N	0.766	1.00
100_D	103_G	0.765	1.00
453_I	456_G	0.761	1.00
371_I	383_V	0.761	1.00
302_L	306_V	0.759	1.00
117_T	177_L	0.759	1.00
269_F	345_S	0.758	1.00
248_L	320_W	0.757	1.00
291_S	295_I	0.754	1.00
151_A	155_G	0.753	1.00
128_G	184_T	0.753	1.00
66_I	80_L	0.752	1.00
90_V	94_A	0.751	1.00
362_F	397_L	0.749	1.00
84_N	88_G	0.749	1.00
230_S	250_Y	0.748	1.00
260_L	263_I	0.748	1.00
356_S	360_N	0.746	1.00
417_S	421_P	0.746	1.00
30_T	315_V	0.743	1.00
29_M	33_A	0.743	1.00
124_V	177_L	0.742	1.00
299_P	425_S	0.738	1.00
237_I	372_V	0.738	1.00
155_G	159_T	0.737	1.00
269_F	349_A	0.737	1.00
251_N	254_V	0.736	1.00
305_M	331_C	0.736	1.00
224_Y	228_N	0.736	1.00
332_V	336_L	0.735	1.00
343_I	395_T	0.734	1.00
370_A	373_I	0.732	1.00
32_L	159_T	0.732	1.00
44_L	169_A	0.731	1.00
73_S	138_E	0.730	1.00
377_M	381_I	0.725	1.00
270_P	274_K	0.725	1.00
347_L	356_S	0.723	1.00
132_R	136_Q	0.719	1.00
303_G	456_G	0.719	1.00
113_P	117_T	0.718	1.00
231_T	243_A	0.717	1.00
228_N	254_V	0.717	1.00
333_V	391_Q	0.715	1.00
38_N	320_W	0.715	1.00
155_G	175_G	0.714	1.00
93_V	97_L	0.712	1.00
80_L	84_N	0.711	1.00
345_S	348_M	0.710	1.00
285_N	289_L	0.708	1.00
31_V	164_H	0.706	1.00
288_K	291_S	0.704	1.00
332_V	335_L	0.703	1.00
359_F	363_K	0.701	1.00
116_K	119_S	0.701	1.00
231_T	247_N	0.700	1.00
211_R	215_W	0.699	1.00
143_K	146_M	0.698	1.00
419_W	423_Y	0.695	1.00
96_F	99_S	0.695	1.00
289_L	342_P	0.693	1.00
452_Q	456_G	0.692	1.00
42_G	244_G	0.691	1.00
127_H	184_T	0.690	1.00
138_E	194_I	0.689	1.00
41_F	244_G	0.686	1.00
38_N	241_G	0.686	1.00
52_A	55_D	0.685	1.00
16_I	20_I	0.684	1.00
459_A	463_M	0.681	1.00
39_H	240_A	0.681	1.00
72_I	205_S	0.677	1.00
435_L	438_V	0.675	1.00
151_A	183_R	0.675	1.00
82_W	85_V	0.675	1.00
300_A	303_G	0.675	1.00
187_F	190_F	0.674	1.00
61_G	213_G	0.672	1.00
376_Q	383_V	0.669	1.00
264_I	268_L	0.669	1.00
99_S	102_I	0.668	1.00
41_F	248_L	0.667	1.00
8_I	11_A	0.667	1.00
216_L	348_M	0.666	1.00
10_G	267_V	0.665	1.00
31_V	160_V	0.662	1.00
177_L	181_A	0.662	1.00
299_P	302_L	0.657	1.00
246_Y	250_Y	0.657	1.00
90_V	93_V	0.656	1.00
405_P	408_G	0.654	1.00
62_I	80_L	0.652	1.00
15_A	19_V	0.651	1.00
261_N	265_T	0.651	1.00
20_I	24_L	0.650	1.00
55_D	59_D	0.650	1.00
71_E	75_L	0.646	1.00
403_I	407_L	0.645	1.00
206_V	210_L	0.645	1.00
198_G	201_F	0.645	1.00
421_P	425_S	0.645	1.00
285_N	288_K	0.644	1.00
156_F	160_V	0.642	1.00
295_I	299_P	0.642	1.00
432_S	436_G	0.640	1.00
366_L	369_P	0.640	1.00
228_N	232_L	0.640	1.00
161_V	165_F	0.639	1.00
125_I	180_S	0.638	1.00
226_N	364_T	0.636	1.00
136_Q	144_I	0.636	1.00
293_V	342_P	0.636	1.00
340_G	395_T	0.635	1.00
392_I	396_I	0.634	1.00
153_L	157_T	0.633	1.00
32_L	41_F	0.633	1.00
308_S	331_C	0.632	1.00
427_P	430_V	0.632	1.00
17_A	149_T	0.631	1.00
229_L	233_V	0.631	1.00
88_G	126_P	0.630	1.00
253_A	256_P	0.630	1.00
135_M	143_K	0.629	1.00
132_R	148_E	0.629	1.00
219_D	360_N	0.629	1.00
212_F	216_L	0.629	1.00
158_C	161_V	0.626	1.00
95_V	99_S	0.625	1.00
420_L	424_L	0.625	1.00
211_R	354_D	0.624	1.00
400_F	405_P	0.624	1.00
117_T	173_I	0.624	1.00
310_N	448_L	0.624	1.00
252_V	316_F	0.619	1.00
275_I	282_L	0.619	1.00
384_T	388_L	0.619	1.00
36_I	169_A	0.618	1.00
78_T	81_Y	0.618	1.00
51_I	122_F	0.618	1.00
209_N	213_G	0.614	1.00
327_L	331_C	0.614	1.00
344_G	356_S	0.613	1.00
20_I	153_L	0.613	1.00
423_Y	426_L	0.613	1.00
313_P	317_G	0.611	1.00
388_L	392_I	0.609	1.00
183_R	187_F	0.609	1.00
437_I	440_K	0.607	1.00
103_G	115_I	0.605	1.00
231_T	250_Y	0.605	1.00
73_S	77_L	0.605	1.00
238_L	379_G	0.604	1.00
313_P	324_I	0.604	1.00
117_T	174_L	0.602	1.00
362_F	365_F	0.602	1.00
117_T	170_M	0.599	1.00
51_I	55_D	0.598	1.00
147_I	183_R	0.597	1.00
353_V	356_S	0.597	1.00
361_V	364_T	0.594	1.00
21_I	25_G	0.592	1.00
147_I	151_A	0.591	1.00
76_E	79_T	0.591	1.00
371_I	386_G	0.591	1.00
263_I	266_R	0.590	1.00
446_G	450_A	0.589	1.00
39_H	43_L	0.588	1.00
33_A	320_W	0.588	1.00
98_L	102_I	0.585	1.00
436_G	448_L	0.585	1.00
299_P	428_T	0.584	1.00
133_A	137_K	0.584	1.00
251_N	316_F	0.583	1.00
431_V	455_T	0.582	1.00
271_A	285_N	0.582	1.00
61_G	68_Q	0.581	1.00
14_S	141_F	0.579	1.00
25_G	29_M	0.579	1.00
83_L	88_G	0.578	1.00
44_L	173_I	0.578	1.00
267_V	271_A	0.577	1.00
219_D	223_N	0.574	1.00
146_M	150_S	0.571	1.00
248_L	323_I	0.570	1.00
63_A	133_A	0.569	1.00
436_G	440_K	0.567	1.00
229_L	367_F	0.566	1.00
391_Q	395_T	0.565	1.00
92_C	123_V	0.564	1.00
366_L	390_V	0.564	1.00
141_F	145_G	0.564	1.00
387_F	390_V	0.563	1.00
46_V	49_V	0.563	1.00
184_T	188_G	0.562	1.00
302_L	305_M	0.560	1.00
432_S	452_Q	0.559	1.00
336_L	388_L	0.558	1.00
46_V	231_T	0.558	1.00
115_I	119_S	0.557	1.00
53_L	224_Y	0.554	1.00
201_F	206_V	0.554	1.00
268_L	272_F	0.554	1.00
69_R	209_N	0.553	1.00
117_T	121_A	0.553	1.00
131_F	191_G	0.553	1.00
291_S	417_S	0.551	1.00
29_M	41_F	0.550	1.00
167_P	170_M	0.549	1.00
408_G	411_Y	0.547	1.00
355_I	359_F	0.546	1.00
172_A	176_Y	0.545	1.00
276_Q	279_T	0.544	1.00
374_G	382_G	0.544	1.00
190_F	194_I	0.544	1.00
73_S	79_T	0.544	1.00
14_S	18_T	0.543	1.00
78_T	198_G	0.542	1.00
421_P	424_L	0.541	1.00
68_Q	349_A	0.541	1.00
230_S	233_V	0.540	1.00
301_L	331_C	0.539	1.00
298_F	302_L	0.539	1.00
151_A	179_N	0.538	1.00
121_A	125_I	0.538	1.00
159_T	163_A	0.537	1.00
369_P	376_Q	0.537	1.00
50_I	54_A	0.536	1.00
152_V	156_F	0.536	1.00
416_L	419_W	0.535	1.00
391_Q	394_N	0.535	1.00
360_N	364_T	0.534	1.00
170_M	174_L	0.534	1.00
223_N	227_T	0.532	1.00
189_Y	192_R	0.530	1.00
104_D	107_N	0.529	1.00
71_E	74_H	0.528	1.00
307_V	453_I	0.528	1.00
262_P	266_R	0.528	1.00
79_T	202_S	0.526	1.00
131_F	187_F	0.526	1.00
242_V	245_G	0.525	1.00
238_L	375_G	0.524	1.00
313_P	318_E	0.524	1.00
171_T	174_L	0.523	1.00
418_L	421_P	0.523	1.00
73_S	80_L	0.522	1.00
337_R	341_N	0.520	1.00
73_S	88_G	0.520	1.00
344_G	348_M	0.520	1.00
124_V	128_G	0.520	1.00
337_R	391_Q	0.519	1.00
200_H	203_L	0.519	1.00
155_G	158_C	0.518	1.00
363_K	390_V	0.517	1.00
40_Q	169_A	0.515	1.00
12_K	19_V	0.514	1.00
452_Q	455_T	0.514	1.00
92_C	119_S	0.513	0.99
426_L	430_V	0.513	0.99
82_W	199_L	0.512	0.99
219_D	357_F	0.512	0.99
346_L	350_K	0.510	0.99
150_S	154_A	0.510	0.99
299_P	303_G	0.509	0.99
32_L	36_I	0.509	0.99
76_E	84_N	0.509	0.99
20_I	23_G	0.508	0.99
80_L	88_G	0.508	0.99
456_G	460_F	0.507	0.99
220_S	224_Y	0.506	0.99
346_L	403_I	0.506	0.99
297_N	331_C	0.505	0.99
226_N	229_L	0.503	0.99
284_V	287_Y	0.502	0.99
424_L	460_F	0.501	0.99
422_F	426_L	0.501	0.99
358_K	401_V	0.501	0.99
449_L	452_Q	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4lz6A	1	0.8333	100	0.418	Contact Map
4humA	1	0.8455	100	0.428	Contact Map
3w4tA	1	0.8171	100	0.431	Contact Map
3mktA	1	0.8415	100	0.441	Contact Map
2cfqA	1	0.8028	72.2	0.935	Contact Map
3wdoA	1	0.7988	70.2	0.936	Contact Map
1pw4A	1	0.4228	35	0.949	Contact Map
4xnjA	1	0.4106	23.1	0.953	Contact Map
4pypA	1	0.8049	20.2	0.954	Contact Map
3dinC	1	0.5711	18.7	0.955	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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