GREMLIN Database
YDHX - Uncharacterized ferredoxin-like protein YdhX
UniProt: P77375 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13958
Length: 222 (177)
Sequences: 2599 (1477)
Seq/√Len: 111.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_T156_E2.9441.00
78_D81_N2.9141.00
128_S141_L2.7951.00
165_P168_V2.7221.00
96_E207_H2.6971.00
103_V133_A2.6221.00
101_I109_S2.5001.00
109_S139_R2.4781.00
39_M153_F2.4401.00
183_S186_I2.1971.00
131_I148_A2.1281.00
98_A111_R2.0671.00
41_H176_L1.9651.00
68_R149_D1.9511.00
112_D160_A1.9391.00
35_V182_D1.9381.00
35_V180_R1.8901.00
103_V129_Y1.8851.00
197_Q200_L1.8631.00
38_A181_E1.8211.00
109_S119_V1.7991.00
128_S131_I1.7851.00
46_C52_C1.7211.00
40_I211_R1.7191.00
142_N149_D1.6991.00
46_C49_C1.6851.00
153_F208_L1.6811.00
46_C171_C1.6781.00
168_V176_L1.6771.00
116_I159_L1.6571.00
112_D118_R1.6521.00
158_R163_F1.6411.00
141_L148_A1.6221.00
197_Q205_K1.5821.00
91_S208_L1.5791.00
47_N173_E1.5681.00
36_R96_E1.5471.00
116_I153_F1.5391.00
155_A160_A1.5271.00
59_T158_R1.5161.00
49_C52_C1.5161.00
190_L195_Y1.5111.00
158_R169_S1.5031.00
104_C124_C1.4881.00
49_C171_C1.4651.00
55_A170_A1.4621.00
60_N156_E1.4451.00
179_G183_S1.4131.00
104_C130_C1.4041.00
99_P204_G1.3981.00
97_D102_D1.3951.00
128_S143_P1.3871.00
194_K201_P1.3781.00
101_I111_R1.3701.00
124_C130_C1.3681.00
188_A191_Q1.3621.00
52_C171_C1.3451.00
177_I187_Q1.3311.00
120_E123_Q1.3171.00
98_A101_I1.3110.99
69_L176_L1.3060.99
44_S211_R1.2550.99
180_R183_S1.2540.99
112_D116_I1.2280.99
164_P169_S1.2250.99
163_F169_S1.2170.99
106_T109_S1.2050.99
50_N53_A1.2050.99
97_D205_K1.2030.99
106_T125_I1.1990.99
51_I170_A1.1880.99
129_Y132_G1.1820.99
91_S176_L1.1810.99
90_Q198_Y1.1760.99
118_R155_A1.1710.99
36_R207_H1.1690.99
96_E205_K1.1660.99
38_A184_P1.1570.99
185_E188_A1.1450.99
195_Y211_R1.1420.99
143_P146_K1.1370.99
55_A166_I1.1180.98
38_A207_H1.1110.98
110_W118_R1.0960.98
99_P133_A1.0890.98
190_L209_Y1.0860.98
112_D155_A1.0850.98
118_R152_D1.0850.98
110_W120_E1.0830.98
89_R210_R1.0830.98
140_Y149_D1.0770.98
78_D82_E1.0710.98
143_P149_D1.0430.97
136_Y206_P1.0390.97
177_I189_W1.0380.97
159_L178_F1.0120.97
199_Q202_G1.0080.97
59_T166_I1.0030.97
116_I155_A1.0030.97
139_R148_A0.9990.97
198_Y204_G0.9960.97
34_E182_D0.9770.96
121_K147_V0.9750.96
193_N211_R0.9710.96
41_H89_R0.9690.96
111_R117_V0.9680.96
197_Q209_Y0.9590.96
69_L89_R0.9550.96
41_H208_L0.9490.95
89_R176_L0.9480.95
190_L193_N0.9480.95
41_H91_S0.9460.95
39_M168_V0.9400.95
119_V139_R0.9250.95
67_S70_S0.9250.95
62_V68_R0.9210.95
188_A192_Q0.9210.95
44_S193_N0.9070.94
70_S90_Q0.9060.94
114_Q160_A0.9050.94
60_N152_D0.8930.94
129_Y133_A0.8800.93
37_Y159_L0.8740.93
70_S140_Y0.8670.93
104_C127_C0.8460.92
43_E89_R0.8420.92
37_Y178_F0.8380.91
181_E185_E0.8350.91
40_I189_W0.8350.91
152_D156_E0.8320.91
153_F178_F0.8310.91
180_R186_I0.8200.91
128_S148_A0.8180.90
124_C127_C0.8170.90
111_R207_H0.8110.90
106_T123_Q0.8110.90
37_Y116_I0.8100.90
91_S153_F0.8080.90
189_W193_N0.8060.90
142_N145_T0.8060.90
106_T127_C0.8050.90
105_P130_C0.8040.90
57_R62_V0.7830.88
36_R182_D0.7820.88
105_P124_C0.7790.88
48_G175_A0.7740.88
197_Q202_G0.7670.87
125_I129_Y0.7600.87
68_R75_P0.7550.87
73_H85_Y0.7530.86
56_C151_C0.7480.86
195_Y199_Q0.7480.86
94_H117_V0.7430.86
51_I173_E0.7430.86
43_E88_F0.7420.86
36_R111_R0.7410.86
101_I110_W0.7400.85
119_V148_A0.7330.85
96_E111_R0.7310.85
106_T110_W0.7270.84
68_R71_I0.7220.84
121_K145_T0.7210.84
131_I141_L0.7200.84
127_C130_C0.7190.84
103_V109_S0.7180.84
78_D83_T0.7180.84
151_C154_C0.7150.83
44_S209_Y0.7120.83
174_H177_I0.7060.83
103_V132_G0.7040.83
153_F159_L0.7020.82
56_C154_C0.6940.82
51_I54_R0.6900.81
199_Q204_G0.6870.81
42_D178_F0.6770.80
48_G71_I0.6740.80
66_G69_L0.6720.80
203_A210_R0.6710.79
73_H87_F0.6700.79
192_Q195_Y0.6690.79
41_H210_R0.6670.79
164_P168_V0.6540.78
69_L91_S0.6530.78
203_A206_P0.6520.77
51_I58_K0.6510.77
69_L72_A0.6510.77
98_A139_R0.6470.77
165_P176_L0.6450.77
48_G138_V0.6430.76
69_L73_H0.6360.76
181_E190_L0.6360.76
189_W192_Q0.6310.75
200_L203_A0.6300.75
39_M178_F0.6180.74
48_G52_C0.6180.74
149_D152_D0.6160.73
128_S132_G0.6150.73
128_S149_D0.6150.73
180_R184_P0.6150.73
48_G171_C0.6130.73
43_E210_R0.6130.73
158_R166_I0.6120.73
45_R175_A0.6080.72
68_R140_Y0.6070.72
141_L145_T0.6050.72
108_A123_Q0.6020.72
195_Y209_Y0.5980.71
78_D84_Q0.5960.71
194_K200_L0.5950.71
195_Y198_Y0.5940.71
79_N82_E0.5930.71
160_A163_F0.5910.70
131_I143_P0.5880.70
37_Y114_Q0.5870.70
60_N166_I0.5870.70
63_P66_G0.5860.70
194_K197_Q0.5830.69
48_G87_F0.5810.69
51_I172_P0.5790.69
36_R181_E0.5750.68
190_L194_K0.5740.68
202_G207_H0.5730.68
121_K149_D0.5720.68
199_Q203_A0.5700.68
114_Q118_R0.5680.67
76_V85_Y0.5680.67
159_L162_G0.5670.67
60_N68_R0.5670.67
47_N172_P0.5670.67
68_R152_D0.5650.67
39_M69_L0.5620.66
94_H159_L0.5610.66
68_R72_A0.5610.66
203_A211_R0.5580.66
39_M91_S0.5540.65
181_E184_P0.5510.65
65_Q75_P0.5480.65
42_D211_R0.5470.64
198_Y202_G0.5430.64
58_K170_A0.5430.64
162_G190_L0.5390.63
197_Q207_H0.5380.63
192_Q200_L0.5350.63
51_I166_I0.5320.62
152_D155_A0.5300.62
63_P144_V0.5290.62
200_L210_R0.5280.62
42_D45_R0.5270.62
140_Y148_A0.5270.62
110_W123_Q0.5240.61
137_Q141_L0.5210.61
120_E164_P0.5210.61
191_Q194_K0.5170.60
59_T169_S0.5160.60
66_G70_S0.5120.59
194_K211_R0.5120.59
139_R184_P0.5100.59
39_M89_R0.5090.59
40_I206_P0.5080.59
35_V79_N0.5060.58
111_R116_I0.5020.58
158_R162_G0.5010.58
79_N191_Q0.5010.58
181_E207_H0.5000.58
165_P178_F0.5000.58
94_H111_R0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ti6B 2 0.8378 100 0.413 Contact Map
2ivfB 1 0.8468 100 0.427 Contact Map
1kqfB 3 0.9324 100 0.477 Contact Map
2vpzB 2 0.8378 100 0.483 Contact Map
1h0hB 1 0.8378 100 0.487 Contact Map
1q16B 2 0.8604 100 0.533 Contact Map
4z3xE 2 0.7342 100 0.622 Contact Map
3mm5B 2 0.9685 99.8 0.73 Contact Map
1jnrB 1 0.6261 99.5 0.789 Contact Map
3gyxB 1 0.6261 99.5 0.791 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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