YNFE - ECOLI - GREMLIN Contacts

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YNFE - Putative dimethyl sulfoxide reductase chain YnfE

UniProt:	P77374	Sequences: MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRNAAAAVQQAREKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYSSGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTDIENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWLPIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGEGDDKTAKTPQWASQITGIPEDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIAMLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTAIRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKRLGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYKAFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEKDEVISPLPVYASTFEGWNSPERRTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHRGEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQHTNLVEIEKI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13843
Length:	808 (670)
Sequences:	8571 (5371)
Seq/√Len:	207.5

ECOLI - YNFE YNFF DMSA TORA TORZ NAPA FDHF BISC FDNG YDEP FDOG NUOG
BACSU - YOAE NASC YYAE YJGC FDHL
HALSA - DMSA
SULSO - Q97XX8 Q97ZA1 Q97V13

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
114_Y	129_R	5.894	1.00
728_I	747_A	4.670	1.00
137_D	566_R	4.491	1.00
735_R	806_E	4.256	1.00
554_K	562_E	3.687	1.00
297_E	362_R	3.406	1.00
722_D	756_G	3.398	1.00
289_G	346_A	3.343	1.00
142_S	145_K	3.333	1.00
735_R	742_E	3.331	1.00
344_Q	354_E	3.258	1.00
687_L	726_R	3.182	1.00
545_P	548_S	3.142	1.00
558_W	562_E	3.093	1.00
293_V	297_E	3.033	1.00
501_V	513_A	2.988	1.00
139_I	515_I	2.903	1.00
138_T	515_I	2.902	1.00
302_Q	306_D	2.845	1.00
145_K	149_Q	2.839	1.00
136_L	566_R	2.828	1.00
721_I	755_P	2.819	1.00
292_W	296_N	2.797	1.00
119_V	128_E	2.771	1.00
131_S	134_E	2.749	1.00
310_V	639_S	2.743	1.00
286_L	350_T	2.698	1.00
737_F	804_E	2.690	1.00
734_V	747_A	2.670	1.00
146_T	154_A	2.667	1.00
738_N	803_V	2.660	1.00
291_A	397_L	2.626	1.00
580_T	583_Q	2.623	1.00
347_S	354_E	2.606	1.00
718_I	747_A	2.581	1.00
737_F	806_E	2.579	1.00
223_K	369_P	2.552	1.00
228_F	287_V	2.515	1.00
130_I	515_I	2.511	1.00
713_R	746_P	2.477	1.00
114_Y	552_E	2.474	1.00
117_K	130_I	2.469	1.00
117_K	138_T	2.469	1.00
274_E	359_K	2.443	1.00
723_A	749_V	2.442	1.00
256_K	363_E	2.440	1.00
117_K	515_I	2.413	1.00
718_I	805_I	2.386	1.00
353_P	356_R	2.381	1.00
356_R	359_K	2.374	1.00
136_L	562_E	2.324	1.00
298_N	302_Q	2.315	1.00
300_V	305_L	2.289	1.00
342_T	345_W	2.278	1.00
143_L	467_F	2.275	1.00
354_E	358_I	2.253	1.00
737_F	742_E	2.245	1.00
726_R	804_E	2.222	1.00
259_V	272_E	2.202	1.00
725_K	755_P	2.181	1.00
222_S	225_V	2.157	1.00
730_N	749_V	2.148	1.00
639_S	643_E	2.147	1.00
138_T	142_S	2.123	1.00
303_P	307_K	2.102	1.00
359_K	363_E	2.060	1.00
139_I	500_V	2.056	1.00
221_N	404_S	2.056	1.00
129_R	552_E	2.049	1.00
745_L	760_M	2.032	1.00
728_I	734_V	2.030	1.00
562_E	566_R	2.017	1.00
716_V	758_S	2.014	1.00
146_T	467_F	1.996	1.00
550_K	553_R	1.981	1.00
601_S	604_E	1.976	1.00
716_V	734_V	1.970	1.00
130_I	138_T	1.953	1.00
733_M	744_R	1.953	1.00
716_V	760_M	1.951	1.00
224_L	258_I	1.935	1.00
292_W	343_P	1.913	1.00
276_L	352_I	1.905	1.00
224_L	363_E	1.903	1.00
276_L	360_L	1.902	1.00
466_K	497_E	1.897	1.00
274_E	356_R	1.883	1.00
604_E	608_M	1.877	1.00
117_K	128_E	1.869	1.00
735_R	744_R	1.865	1.00
282_T	349_I	1.853	1.00
716_V	736_V	1.822	1.00
718_I	758_S	1.822	1.00
295_I	312_Y	1.817	1.00
67_R	86_D	1.816	1.00
730_N	748_K	1.815	1.00
286_L	357_I	1.814	1.00
113_N	551_F	1.779	1.00
293_V	362_R	1.774	1.00
299_L	365_G	1.765	1.00
506_M	510_A	1.765	1.00
295_I	331_I	1.753	1.00
137_D	141_S	1.745	1.00
687_L	758_S	1.740	1.00
297_E	358_I	1.737	1.00
344_Q	358_I	1.729	1.00
562_E	565_K	1.719	1.00
526_E	545_P	1.716	1.00
729_A	732_D	1.704	1.00
364_I	370_A	1.671	1.00
498_M	515_I	1.663	1.00
364_I	398_T	1.657	1.00
469_W	502_I	1.651	1.00
347_S	357_I	1.650	1.00
116_M	516_L	1.650	1.00
758_S	803_V	1.650	1.00
721_I	724_Q	1.649	1.00
293_V	343_P	1.639	1.00
260_I	286_L	1.630	1.00
144_K	148_E	1.621	1.00
293_V	358_I	1.618	1.00
733_M	746_P	1.616	1.00
717_W	750_T	1.616	1.00
65_A	88_Y	1.610	1.00
520_L	555_P	1.605	1.00
692_F	759_A	1.601	1.00
397_L	644_I	1.600	1.00
403_I	406_G	1.597	1.00
347_S	353_P	1.593	1.00
139_I	517_L	1.582	1.00
130_I	134_E	1.556	1.00
299_L	362_R	1.555	1.00
119_V	126_K	1.553	1.00
294_L	300_V	1.550	1.00
143_L	500_V	1.550	1.00
226_V	260_I	1.546	1.00
496_C	499_I	1.546	1.00
274_E	363_E	1.537	1.00
305_L	312_Y	1.537	1.00
687_L	722_D	1.518	1.00
150_Y	466_K	1.515	1.00
743_V	760_M	1.507	1.00
104_R	707_L	1.506	1.00
682_R	739_H	1.506	1.00
470_N	499_I	1.497	1.00
52_V	70_V	1.493	1.00
346_A	357_I	1.487	1.00
69_H	79_E	1.487	1.00
579_R	583_Q	1.485	1.00
116_M	129_R	1.480	1.00
182_M	187_G	1.477	1.00
285_A	349_I	1.469	1.00
286_L	360_L	1.469	1.00
309_C	644_I	1.464	1.00
250_R	273_D	1.454	1.00
362_R	366_T	1.450	1.00
224_L	360_L	1.439	1.00
296_N	358_I	1.437	1.00
582_E	586_Q	1.428	1.00
68_L	75_V	1.426	1.00
249_A	255_A	1.418	1.00
134_E	138_T	1.408	1.00
488_E	494_S	1.404	1.00
300_V	312_Y	1.403	1.00
115_P	132_W	1.398	1.00
506_M	516_L	1.387	1.00
138_T	498_M	1.386	1.00
226_V	360_L	1.382	1.00
487_H	494_S	1.380	1.00
293_V	299_L	1.380	1.00
687_L	804_E	1.367	1.00
157_I	182_M	1.366	1.00
341_K	349_I	1.366	1.00
554_K	558_W	1.363	1.00
501_V	510_A	1.363	1.00
544_Q	606_K	1.362	1.00
726_R	805_I	1.357	1.00
141_S	145_K	1.356	1.00
720_P	751_P	1.353	1.00
341_K	345_W	1.349	1.00
51_V	67_R	1.348	1.00
262_P	275_W	1.347	1.00
295_I	328_K	1.345	1.00
147_V	155_V	1.344	1.00
53_W	67_R	1.342	1.00
278_I	352_I	1.341	1.00
144_K	147_V	1.341	1.00
504_N	521_M	1.338	1.00
583_Q	586_Q	1.333	1.00
565_K	570_D	1.331	1.00
701_T	704_N	1.329	1.00
156_Y	465_I	1.322	1.00
296_N	339_T	1.320	1.00
54_G	68_L	1.314	1.00
622_A	625_A	1.314	1.00
259_V	268_A	1.309	1.00
555_P	558_W	1.309	1.00
294_L	365_G	1.306	1.00
432_S	436_F	1.291	1.00
482_D	787_L	1.286	1.00
716_V	745_L	1.283	1.00
351_G	754_L	1.282	1.00
341_K	346_A	1.276	1.00
303_P	306_D	1.275	1.00
53_W	81_D	1.273	1.00
134_E	515_I	1.272	1.00
295_I	300_V	1.269	1.00
329_A	339_T	1.268	1.00
274_E	360_L	1.264	1.00
75_V	106_I	1.260	1.00
616_P	620_F	1.259	1.00
345_W	348_Q	1.258	1.00
623_Y	626_F	1.257	1.00
248_K	251_E	1.249	1.00
276_L	356_R	1.248	1.00
715_E	748_K	1.245	1.00
310_V	643_E	1.241	1.00
264_Y	269_A	1.240	1.00
293_V	296_N	1.239	1.00
290_I	364_I	1.237	1.00
68_L	78_V	1.235	1.00
282_T	350_T	1.233	1.00
147_V	185_Y	1.232	1.00
290_I	361_A	1.231	1.00
367_A	370_A	1.226	1.00
311_G	314_E	1.223	1.00
223_K	253_S	1.221	1.00
118_R	127_F	1.220	1.00
637_T	643_E	1.219	1.00
140_A	566_R	1.215	1.00
51_V	69_H	1.214	1.00
622_A	626_F	1.209	1.00
155_V	467_F	1.204	1.00
684_T	739_H	1.200	1.00
719_N	755_P	1.198	1.00
292_W	339_T	1.197	1.00
456_R	485_K	1.193	1.00
502_I	559_I	1.192	1.00
223_K	368_K	1.191	1.00
67_R	81_D	1.190	1.00
750_T	753_I	1.190	1.00
603_D	607_K	1.189	1.00
136_L	554_K	1.184	1.00
293_V	357_I	1.184	1.00
147_V	152_N	1.183	1.00
287_V	391_I	1.178	1.00
378_P	391_I	1.178	1.00
289_G	357_I	1.176	1.00
586_Q	589_Y	1.175	1.00
482_D	485_K	1.172	1.00
558_W	565_K	1.172	1.00
590_A	593_L	1.165	1.00
684_T	804_E	1.165	1.00
299_L	366_T	1.163	1.00
218_D	221_N	1.162	1.00
302_Q	328_K	1.161	1.00
520_L	553_R	1.160	1.00
74_E	107_N	1.159	1.00
485_K	488_E	1.158	1.00
314_E	329_A	1.156	1.00
294_L	398_T	1.152	1.00
258_I	360_L	1.149	1.00
400_N	406_G	1.148	1.00
542_F	606_K	1.148	1.00
67_R	79_E	1.142	1.00
49_E	71_K	1.141	1.00
278_I	282_T	1.139	1.00
203_A	388_A	1.133	1.00
717_W	748_K	1.131	1.00
119_V	124_E	1.128	1.00
225_V	255_A	1.125	1.00
106_I	547_T	1.123	1.00
290_I	360_L	1.122	1.00
227_M	230_N	1.122	1.00
467_F	500_V	1.121	1.00
223_K	367_A	1.117	1.00
110_D	704_N	1.117	1.00
80_T	93_V	1.116	1.00
760_M	781_V	1.112	1.00
340_A	345_W	1.109	1.00
226_V	290_I	1.108	1.00
454_G	465_I	1.106	1.00
736_V	760_M	1.100	1.00
570_D	573_Q	1.099	1.00
502_I	519_D	1.096	1.00
202_C	792_L	1.094	1.00
364_I	372_I	1.092	1.00
269_A	752_R	1.092	1.00
346_A	350_T	1.090	1.00
146_T	498_M	1.088	1.00
494_S	497_E	1.085	1.00
154_A	466_K	1.080	1.00
224_L	367_A	1.080	1.00
585_L	589_Y	1.078	1.00
290_I	294_L	1.077	1.00
586_Q	603_D	1.077	1.00
605_L	610_I	1.076	1.00
647_S	651_E	1.076	1.00
219_I	371_Y	1.075	1.00
689_L	803_V	1.072	1.00
471_Y	560_L	1.072	1.00
355_D	358_I	1.068	1.00
305_L	644_I	1.062	1.00
470_N	509_S	1.060	1.00
142_S	146_T	1.057	1.00
146_T	497_E	1.052	1.00
112_L	516_L	1.052	1.00
139_I	498_M	1.051	1.00
143_L	567_L	1.047	1.00
224_L	370_A	1.045	1.00
461_L	485_K	1.044	1.00
517_L	559_I	1.042	1.00
250_R	271_R	1.041	1.00
113_N	129_R	1.040	1.00
78_V	103_R	1.035	1.00
127_F	516_L	1.034	1.00
352_I	357_I	1.034	1.00
717_W	752_R	1.031	1.00
136_L	558_W	1.029	1.00
758_S	805_I	1.028	1.00
151_G	154_A	1.026	1.00
225_V	246_L	1.021	1.00
279_R	754_L	1.018	1.00
719_N	749_V	1.018	1.00
719_N	753_I	1.015	1.00
287_V	390_A	1.015	1.00
347_S	350_T	1.013	1.00
81_D	86_D	1.013	1.00
309_C	396_I	1.010	1.00
228_F	260_I	1.005	1.00
65_A	81_D	1.005	1.00
685_F	804_E	1.002	1.00
343_P	358_I	0.997	1.00
51_V	79_E	0.995	1.00
430_K	433_I	0.995	1.00
292_W	342_T	0.992	1.00
69_H	77_W	0.991	1.00
132_W	517_L	0.990	1.00
260_I	360_L	0.990	1.00
484_N	488_E	0.986	1.00
540_L	600_P	0.985	1.00
523_V	546_V	0.983	1.00
690_F	757_V	0.981	1.00
260_I	276_L	0.979	1.00
128_E	134_E	0.979	1.00
113_N	550_K	0.977	1.00
533_Y	539_Y	0.977	1.00
393_M	644_I	0.976	1.00
685_F	738_N	0.975	1.00
347_S	352_I	0.971	1.00
586_Q	590_A	0.970	1.00
280_P	757_V	0.968	1.00
582_E	606_K	0.967	1.00
258_I	363_E	0.965	1.00
290_I	394_L	0.964	1.00
488_E	495_K	0.963	1.00
459_D	464_P	0.963	1.00
312_Y	328_K	0.963	1.00
526_E	542_F	0.962	1.00
133_D	566_R	0.955	0.99
300_V	397_L	0.954	0.99
143_L	469_W	0.953	0.99
526_E	582_E	0.952	0.99
207_T	389_R	0.948	0.99
721_I	751_P	0.947	0.99
686_P	804_E	0.944	0.99
155_V	185_Y	0.942	0.99
460_K	463_V	0.941	0.99
582_E	602_Y	0.938	0.99
743_V	784_L	0.938	0.99
181_L	567_L	0.938	0.99
310_V	641_K	0.938	0.99
68_L	523_V	0.937	0.99
510_A	516_L	0.936	0.99
227_M	257_M	0.936	0.99
258_I	274_E	0.934	0.99
716_V	805_I	0.933	0.99
181_L	560_L	0.932	0.99
579_R	587_H	0.931	0.99
132_W	559_I	0.930	0.99
682_R	802_L	0.928	0.99
476_L	487_H	0.926	0.99
312_Y	397_L	0.925	0.99
427_N	430_K	0.925	0.99
289_G	293_V	0.924	0.99
370_A	400_N	0.920	0.99
469_W	563_V	0.920	0.99
56_C	60_C	0.917	0.99
359_K	362_R	0.916	0.99
605_L	608_M	0.916	0.99
260_I	278_I	0.916	0.99
328_K	331_I	0.915	0.99
740_R	801_N	0.914	0.99
345_W	349_I	0.914	0.99
264_Y	752_R	0.913	0.99
293_V	361_A	0.913	0.99
354_E	357_I	0.910	0.99
358_I	362_R	0.905	0.99
745_L	781_V	0.904	0.99
139_I	563_V	0.903	0.99
467_F	498_M	0.903	0.99
436_F	439_T	0.901	0.99
352_I	356_R	0.900	0.99
71_K	76_T	0.898	0.99
73_N	548_S	0.897	0.99
519_D	559_I	0.895	0.99
740_R	785_T	0.894	0.99
68_L	546_V	0.894	0.99
718_I	723_A	0.893	0.99
278_I	286_L	0.893	0.99
620_F	623_Y	0.892	0.99
284_A	387_T	0.891	0.99
247_E	250_R	0.891	0.99
347_S	355_D	0.889	0.99
526_E	581_Q	0.884	0.99
136_L	563_V	0.881	0.99
621_V	624_K	0.881	0.99
116_M	506_M	0.880	0.99
313_D	328_K	0.879	0.99
256_K	273_D	0.879	0.99
446_P	449_T	0.874	0.99
286_L	290_I	0.873	0.99
468_I	496_C	0.873	0.99
718_I	728_I	0.873	0.99
140_A	144_K	0.871	0.99
50_K	73_N	0.869	0.99
396_I	642_I	0.868	0.99
507_T	510_A	0.866	0.99
434_S	437_S	0.866	0.99
687_L	805_I	0.865	0.99
296_N	343_P	0.865	0.99
608_M	611_Y	0.864	0.99
277_P	754_L	0.863	0.99
227_M	267_T	0.863	0.99
285_A	289_G	0.862	0.99
520_L	549_E	0.861	0.99
262_P	277_P	0.861	0.99
224_L	256_K	0.861	0.99
256_K	274_E	0.861	0.99
56_C	64_C	0.859	0.99
718_I	734_V	0.859	0.99
160_S	189_L	0.858	0.99
264_Y	751_P	0.857	0.99
461_L	488_E	0.856	0.99
630_P	633_N	0.856	0.99
143_L	147_V	0.855	0.99
294_L	394_L	0.854	0.99
433_I	437_S	0.854	0.99
301_D	403_I	0.854	0.99
547_T	550_K	0.852	0.99
754_L	757_V	0.851	0.99
343_P	346_A	0.850	0.99
293_V	354_E	0.849	0.99
249_A	253_S	0.849	0.99
232_P	246_L	0.847	0.99
88_Y	91_H	0.847	0.99
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602_Y	606_K	0.846	0.99
369_P	406_G	0.846	0.99
355_D	359_K	0.846	0.99
362_R	365_G	0.845	0.99
62_S	238_S	0.843	0.99
225_V	249_A	0.842	0.99
288_A	341_K	0.841	0.99
476_L	483_I	0.840	0.99
60_C	64_C	0.840	0.99
681_E	802_L	0.840	0.99
279_R	351_G	0.837	0.99
115_P	131_S	0.836	0.99
736_V	803_V	0.836	0.99
305_L	397_L	0.833	0.99
250_R	257_M	0.833	0.99
376_W	380_R	0.832	0.99
52_V	546_V	0.832	0.99
55_A	541_I	0.828	0.99
66_L	95_A	0.828	0.99
739_H	802_L	0.824	0.99
220_E	245_L	0.821	0.98
429_V	432_S	0.819	0.98
71_K	74_E	0.815	0.98
342_T	346_A	0.813	0.98
638_P	643_E	0.813	0.98
289_G	345_W	0.810	0.98
508_S	765_W	0.810	0.98
425_L	430_K	0.810	0.98
139_I	142_S	0.810	0.98
108_H	505_F	0.806	0.98
620_F	624_K	0.803	0.98
476_L	490_L	0.800	0.98
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470_N	501_V	0.796	0.98
728_I	749_V	0.795	0.98
142_S	498_M	0.794	0.98
289_G	348_Q	0.791	0.98
218_D	405_G	0.791	0.98
545_P	549_E	0.790	0.98
434_S	438_W	0.789	0.98
106_I	521_M	0.789	0.98
435_C	441_A	0.789	0.98
461_L	495_K	0.789	0.98
720_P	724_Q	0.788	0.98
143_L	185_Y	0.787	0.98
714_Q	764_A	0.787	0.98
233_A	267_T	0.783	0.98
797_P	800_T	0.781	0.98
372_I	395_P	0.780	0.98
149_Q	466_K	0.780	0.98
682_R	686_P	0.779	0.98
449_T	453_D	0.778	0.98
117_K	134_E	0.778	0.98
132_W	554_K	0.778	0.98
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264_Y	277_P	0.774	0.98
53_W	87_E	0.774	0.98
52_V	68_L	0.773	0.98
561_S	565_K	0.772	0.98
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130_I	135_A	0.768	0.98
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736_V	745_L	0.768	0.98
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723_A	728_I	0.766	0.98
526_E	544_Q	0.766	0.98
635_L	642_I	0.766	0.98
718_I	749_V	0.763	0.98
568_G	573_Q	0.761	0.97
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682_R	685_F	0.759	0.97
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150_Y	154_A	0.757	0.97
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433_I	436_F	0.754	0.97
369_P	403_I	0.750	0.97
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554_K	559_I	0.748	0.97
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445_G	448_M	0.747	0.97
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619_H	622_A	0.737	0.97
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520_L	525_Q	0.727	0.97
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363_E	367_A	0.708	0.96
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396_I	644_I	0.702	0.96
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494_S	512_Y	0.695	0.96
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293_V	365_G	0.689	0.96
291_A	393_M	0.689	0.96
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786_T	801_N	0.603	0.91
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600_P	611_Y	0.583	0.90
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312_Y	331_I	0.580	0.90
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566_R	569_P	0.569	0.89
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475_T	509_S	0.535	0.85
308_Y	632_A	0.535	0.85
243_T	246_L	0.535	0.85
135_A	139_I	0.535	0.85
619_H	624_K	0.534	0.85
500_V	515_I	0.534	0.85
581_Q	592_M	0.534	0.85
81_D	87_E	0.534	0.85
342_T	347_S	0.534	0.85
568_G	571_V	0.534	0.85
133_D	554_K	0.534	0.85
620_F	625_A	0.533	0.85
312_Y	644_I	0.532	0.85
438_W	443_D	0.532	0.85
198_A	202_C	0.532	0.85
146_T	155_V	0.532	0.85
604_E	615_D	0.532	0.85
602_Y	608_M	0.532	0.85
786_T	797_P	0.531	0.85
291_A	295_I	0.531	0.85
290_I	370_A	0.530	0.85
424_V	428_P	0.530	0.85
261_D	275_W	0.529	0.85
714_Q	761_G	0.529	0.85
738_N	804_E	0.528	0.85
720_P	750_T	0.528	0.85
689_L	736_V	0.528	0.85
288_A	331_I	0.528	0.85
263_R	692_F	0.527	0.85
453_D	485_K	0.527	0.85
346_A	349_I	0.526	0.85
385_E	790_S	0.525	0.84
311_G	331_I	0.524	0.84
195_Y	480_H	0.524	0.84
226_V	394_L	0.524	0.84
282_T	285_A	0.524	0.84
402_G	407_N	0.524	0.84
290_I	398_T	0.523	0.84
185_Y	567_L	0.523	0.84
428_P	431_T	0.523	0.84
431_T	444_H	0.522	0.84
586_Q	591_K	0.522	0.84
208_Y	401_V	0.522	0.84
56_C	96_C	0.521	0.84
117_K	139_I	0.521	0.84
292_W	295_I	0.521	0.84
290_I	362_R	0.521	0.84
279_R	688_Q	0.521	0.84
542_F	602_Y	0.521	0.84
637_T	640_G	0.521	0.84
602_Y	610_I	0.520	0.84
581_Q	585_L	0.520	0.84
481_S	796_N	0.520	0.84
557_Y	561_S	0.519	0.84
583_Q	590_A	0.519	0.84
112_L	506_M	0.518	0.84
468_I	490_L	0.518	0.84
738_N	801_N	0.518	0.84
140_A	563_V	0.518	0.84
265_T	268_A	0.517	0.83
262_P	278_I	0.517	0.83
637_T	641_K	0.517	0.83
290_I	365_G	0.517	0.83
733_M	747_A	0.516	0.83
70_V	76_T	0.516	0.83
193_G	198_A	0.516	0.83
720_P	749_V	0.516	0.83
732_D	806_E	0.516	0.83
631_E	634_P	0.516	0.83
687_L	719_N	0.516	0.83
292_W	346_A	0.515	0.83
431_T	438_W	0.515	0.83
524_E	553_R	0.515	0.83
214_N	371_Y	0.514	0.83
636_K	639_S	0.514	0.83
202_C	793_A	0.514	0.83
228_F	394_L	0.514	0.83
234_E	717_W	0.513	0.83
674_F	679_S	0.513	0.83
228_F	286_L	0.512	0.83
133_D	137_D	0.512	0.83
308_Y	634_P	0.511	0.83
552_E	555_P	0.511	0.83
469_W	500_V	0.510	0.83
277_P	356_R	0.510	0.83
722_D	726_R	0.510	0.83
738_N	784_L	0.509	0.83
502_I	556_I	0.509	0.83
284_A	649_L	0.509	0.83
230_N	375_G	0.508	0.82
382_A	674_F	0.506	0.82
342_T	348_Q	0.506	0.82
564_A	570_D	0.505	0.82
561_S	564_A	0.505	0.82
351_G	756_G	0.504	0.82
600_P	610_I	0.504	0.82
738_N	802_L	0.504	0.82
584_W	588_L	0.504	0.82
639_S	642_I	0.504	0.82
605_L	611_Y	0.504	0.82
233_A	243_T	0.503	0.82
286_L	347_S	0.502	0.82
467_F	496_C	0.501	0.82
646_S	649_L	0.501	0.82
598_A	601_S	0.501	0.82
437_S	440_D	0.500	0.81
66_L	102_I	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1kqfA	3	0.8899	100	0.223	Contact Map
2vpzA	1	0.8515	100	0.229	Contact Map
2ivfA	1	0.8911	100	0.241	Contact Map
1h0hA	1	0.8899	100	0.257	Contact Map
2e7zA	1	0.8391	100	0.26	Contact Map
1q16A	2	0.948	100	0.261	Contact Map
2iv2X	1	0.7958	100	0.284	Contact Map
2napA	1	0.8317	100	0.29	Contact Map
3ml1A	1	0.87	100	0.294	Contact Map
1tmoA	1	0.8762	100	0.295	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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