GLXK2 - ECOLI - GREMLIN Contacts

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GLXK2 - Glycerate kinase

UniProt:	P77364	Sequences: MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQALAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13621
Length:	381 (371)
Sequences:	2549 (1922)
Seq/√Len:	99.8

ECOLI - GLXK2 GLXK1
BACSU - GLXK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
94_S	114_T	3.422	1.00
67_G	71_E	3.157	1.00
269_I	307_G	2.865	1.00
128_H	187_H	2.770	1.00
29_T	367_R	2.605	1.00
25_A	363_F	2.604	1.00
139_V	205_A	2.590	1.00
234_Q	240_N	2.487	1.00
66_C	116_E	2.472	1.00
77_Y	120_H	2.446	1.00
79_L	126_I	2.435	1.00
273_L	278_L	2.383	1.00
128_H	189_E	2.371	1.00
295_I	321_G	2.363	1.00
279_A	314_Q	2.352	1.00
5_I	23_I	2.321	1.00
143_M	153_F	2.318	1.00
294_R	325_V	2.294	1.00
279_A	311_V	2.239	1.00
151_V	176_M	2.208	1.00
277_N	280_Q	2.199	1.00
27_F	370_A	2.198	1.00
24_K	38_C	2.180	1.00
241_V	255_I	2.168	1.00
71_E	103_K	2.157	1.00
29_T	363_F	2.136	1.00
64_E	74_N	2.112	1.00
62_T	74_N	2.086	1.00
141_G	229_Y	2.074	1.00
215_T	218_M	2.069	1.00
22_A	26_G	2.064	1.00
4_V	285_A	2.011	1.00
37_I	281_A	1.985	1.00
199_V	223_E	1.959	1.00
53_V	78_G	1.955	1.00
24_K	28_S	1.941	1.00
2_K	35_N	1.932	1.00
367_R	371_C	1.927	1.00
20_C	38_C	1.915	1.00
214_A	222_L	1.867	1.00
233_L	260_F	1.865	1.00
161_L	167_N	1.863	1.00
100_A	103_K	1.860	1.00
84_K	127_R	1.857	1.00
23_I	366_A	1.839	1.00
155_D	159_Q	1.832	1.00
191_A	271_I	1.826	1.00
90_M	253_M	1.810	1.00
151_V	179_C	1.810	1.00
61_V	124_N	1.809	1.00
131_L	257_A	1.806	1.00
210_P	219_V	1.806	1.00
21_Q	38_C	1.793	1.00
123_D	182_R	1.785	1.00
76_F	92_A	1.773	1.00
42_A	48_T	1.754	1.00
18_K	359_E	1.733	1.00
50_D	60_I	1.729	1.00
65_V	116_E	1.725	1.00
299_T	306_L	1.711	1.00
64_E	72_K	1.701	1.00
295_I	323_A	1.697	1.00
129_I	186_C	1.688	1.00
127_R	185_N	1.688	1.00
147_Q	163_A	1.665	1.00
56_T	81_G	1.646	1.00
192_C	265_I	1.643	1.00
129_I	188_I	1.642	1.00
155_D	170_R	1.640	1.00
68_P	98_L	1.636	1.00
5_I	36_Y	1.632	1.00
90_M	133_I	1.630	1.00
105_N	108_L	1.624	1.00
133_I	190_V	1.611	1.00
66_C	110_S	1.599	1.00
77_Y	124_N	1.589	1.00
60_I	76_F	1.589	1.00
2_K	284_G	1.584	1.00
205_A	219_V	1.583	1.00
123_D	180_D	1.565	1.00
161_L	171_V	1.561	1.00
14_L	358_G	1.558	1.00
99_V	103_K	1.531	1.00
41_I	304_A	1.530	1.00
153_F	171_V	1.524	1.00
187_H	264_D	1.516	1.00
321_G	338_I	1.516	1.00
39_L	281_A	1.505	1.00
231_R	242_C	1.502	1.00
3_I	287_L	1.500	1.00
67_G	73_V	1.499	1.00
146_A	256_A	1.478	1.00
279_A	315_F	1.478	1.00
166_G	225_G	1.468	1.00
120_H	124_N	1.466	1.00
147_Q	153_F	1.466	1.00
23_I	289_I	1.464	1.00
162_A	167_N	1.462	1.00
282_V	317_V	1.459	1.00
278_L	311_V	1.456	1.00
15_S	18_K	1.453	1.00
14_L	359_E	1.452	1.00
357_S	360_T	1.439	1.00
93_A	114_T	1.432	1.00
322_I	366_A	1.430	1.00
269_I	273_L	1.420	1.00
199_V	242_C	1.419	1.00
19_C	362_L	1.417	1.00
350_P	353_E	1.401	1.00
198_L	255_I	1.400	1.00
313_K	339_D	1.398	1.00
66_C	70_G	1.395	1.00
127_R	186_C	1.378	0.99
152_R	175_E	1.377	0.99
152_R	160_A	1.370	0.99
189_E	266_K	1.361	0.99
288_V	308_V	1.343	0.99
146_A	151_V	1.341	0.99
349_A	354_V	1.334	0.99
274_N	311_V	1.330	0.99
111_S	138_T	1.327	0.99
63_L	77_Y	1.325	0.99
2_K	37_I	1.322	0.99
65_V	93_A	1.304	0.99
7_P	23_I	1.299	0.99
107_L	221_E	1.292	0.99
195_D	202_R	1.291	0.99
247_G	258_A	1.290	0.99
7_P	20_C	1.290	0.99
122_L	186_C	1.287	0.99
31_F	34_A	1.280	0.99
146_A	260_F	1.279	0.99
165_G	225_G	1.267	0.99
122_L	182_R	1.265	0.99
284_G	317_V	1.256	0.99
72_K	116_E	1.255	0.99
143_M	161_L	1.250	0.99
63_L	117_L	1.247	0.99
282_V	288_V	1.240	0.99
7_P	16_A	1.239	0.99
122_L	180_D	1.236	0.99
41_I	273_L	1.225	0.99
233_L	255_I	1.224	0.99
27_F	34_A	1.212	0.99
205_A	214_A	1.210	0.99
280_Q	283_Q	1.208	0.99
202_R	301_G	1.202	0.99
119_R	180_D	1.201	0.99
108_L	166_G	1.201	0.99
12_E	97_M	1.195	0.98
282_V	311_V	1.189	0.98
164_N	167_N	1.188	0.98
165_G	222_L	1.187	0.98
80_T	87_V	1.186	0.98
342_F	369_I	1.185	0.98
190_V	265_I	1.183	0.98
199_V	227_Q	1.175	0.98
169_A	221_E	1.158	0.98
93_A	117_L	1.158	0.98
349_A	361_N	1.154	0.98
257_A	263_A	1.146	0.98
111_S	253_M	1.143	0.98
118_I	188_I	1.142	0.98
206_A	220_E	1.141	0.98
112_F	163_A	1.140	0.98
75_A	117_L	1.140	0.98
107_L	218_M	1.139	0.98
9_S	46_E	1.133	0.98
27_F	36_Y	1.127	0.98
147_Q	160_A	1.118	0.98
346_P	361_N	1.110	0.98
366_A	370_A	1.103	0.97
25_A	359_E	1.099	0.97
49_V	92_A	1.098	0.97
143_M	229_Y	1.098	0.97
52_M	275_A	1.092	0.97
244_M	258_A	1.092	0.97
130_I	271_I	1.090	0.97
309_A	338_I	1.086	0.97
49_V	89_E	1.084	0.97
214_A	219_V	1.069	0.97
323_A	326_L	1.068	0.97
325_V	348_L	1.066	0.97
61_V	77_Y	1.061	0.97
5_I	20_C	1.052	0.97
342_F	372_A	1.052	0.97
14_L	19_C	1.045	0.96
227_Q	231_R	1.044	0.96
112_F	116_E	1.041	0.96
154_L	173_S	1.039	0.96
266_K	274_N	1.036	0.96
112_F	148_A	1.035	0.96
206_A	219_V	1.034	0.96
23_I	322_I	1.033	0.96
50_D	54_A	1.028	0.96
53_V	60_I	1.023	0.96
118_I	145_M	1.022	0.96
119_R	123_D	1.014	0.96
85_T	128_H	1.013	0.96
56_T	80_T	1.012	0.96
90_M	111_S	1.004	0.96
345_L	354_V	1.002	0.95
133_I	250_A	1.002	0.95
353_E	357_S	0.994	0.95
167_N	170_R	0.986	0.95
145_M	253_M	0.985	0.95
273_L	311_V	0.984	0.95
183_L	188_I	0.981	0.95
218_M	221_E	0.980	0.95
143_M	147_Q	0.979	0.95
49_V	132_G	0.975	0.95
342_F	365_S	0.974	0.95
4_V	317_V	0.969	0.95
30_L	367_R	0.967	0.94
239_I	262_N	0.963	0.94
24_K	36_Y	0.959	0.94
306_L	310_S	0.958	0.94
342_F	368_N	0.950	0.94
153_F	229_Y	0.949	0.94
207_V	297_S	0.949	0.94
28_S	36_Y	0.948	0.94
195_D	301_G	0.948	0.94
326_L	341_V	0.944	0.94
169_A	225_G	0.942	0.94
111_S	256_A	0.936	0.93
17_E	21_Q	0.932	0.93
26_G	30_L	0.930	0.93
305_P	338_I	0.930	0.93
12_E	104_R	0.930	0.93
88_I	117_L	0.929	0.93
197_P	247_G	0.928	0.93
156_A	172_A	0.922	0.93
75_A	92_A	0.922	0.93
190_V	257_A	0.920	0.93
205_A	223_E	0.917	0.93
75_A	93_A	0.916	0.93
58_G	78_G	0.907	0.92
39_L	276_V	0.906	0.92
143_M	171_V	0.902	0.92
3_I	31_F	0.900	0.92
322_I	369_I	0.896	0.92
63_L	120_H	0.894	0.92
147_Q	164_N	0.882	0.91
283_Q	315_F	0.881	0.91
106_P	109_A	0.880	0.91
227_Q	242_C	0.879	0.91
27_F	289_I	0.876	0.91
361_N	368_N	0.875	0.91
330_V	341_V	0.874	0.91
62_T	76_F	0.870	0.91
85_T	130_I	0.870	0.91
234_Q	242_C	0.866	0.91
65_V	75_A	0.865	0.90
163_A	167_N	0.864	0.90
13_S	358_G	0.860	0.90
196_N	207_V	0.857	0.90
105_N	109_A	0.853	0.90
4_V	284_G	0.853	0.90
205_A	225_G	0.851	0.90
130_I	191_A	0.849	0.90
49_V	76_F	0.847	0.90
232_V	235_Q	0.844	0.89
69_M	99_V	0.841	0.89
8_D	46_E	0.839	0.89
105_N	218_M	0.838	0.89
359_E	363_F	0.834	0.89
205_A	226_L	0.833	0.89
51_A	87_V	0.829	0.89
295_I	341_V	0.828	0.88
299_T	323_A	0.826	0.88
230_A	242_C	0.824	0.88
4_V	282_V	0.822	0.88
31_F	370_A	0.821	0.88
5_I	289_I	0.820	0.88
90_M	145_M	0.819	0.88
15_S	50_D	0.816	0.88
90_M	94_S	0.813	0.88
294_R	327_G	0.811	0.87
257_A	261_L	0.807	0.87
312_A	319_V	0.807	0.87
17_E	54_A	0.805	0.87
23_I	370_A	0.803	0.87
361_N	364_N	0.800	0.87
288_V	312_A	0.797	0.87
219_V	226_L	0.797	0.87
287_L	318_P	0.796	0.86
306_L	333_V	0.796	0.86
209_G	214_A	0.793	0.86
332_V	335_Q	0.791	0.86
133_I	254_G	0.791	0.86
233_L	259_V	0.790	0.86
107_L	166_G	0.788	0.86
67_G	99_V	0.787	0.86
30_L	370_A	0.785	0.86
51_A	54_A	0.785	0.86
188_I	260_F	0.783	0.86
12_E	355_L	0.775	0.85
7_P	19_C	0.775	0.85
152_R	178_E	0.771	0.85
228_N	232_V	0.768	0.84
118_I	129_I	0.762	0.84
300_A	333_V	0.760	0.84
306_L	338_I	0.759	0.84
143_M	164_N	0.759	0.84
110_S	163_A	0.759	0.84
164_N	171_V	0.756	0.83
297_S	332_V	0.755	0.83
311_V	315_F	0.755	0.83
326_L	330_V	0.755	0.83
121_A	126_I	0.754	0.83
357_S	361_N	0.752	0.83
346_P	349_A	0.751	0.83
81_G	84_K	0.750	0.83
277_N	281_A	0.749	0.83
229_Y	233_L	0.749	0.83
158_G	173_S	0.748	0.83
35_N	284_G	0.747	0.83
176_M	179_C	0.747	0.83
104_R	109_A	0.746	0.83
190_V	263_A	0.743	0.82
22_A	359_E	0.739	0.82
167_N	171_V	0.738	0.82
58_G	80_T	0.738	0.82
347_R	357_S	0.737	0.82
300_A	336_Y	0.736	0.82
295_I	299_T	0.736	0.82
255_I	259_V	0.736	0.82
101_P	352_A	0.735	0.82
86_A	121_A	0.733	0.82
219_V	223_E	0.732	0.81
27_F	366_A	0.730	0.81
69_M	109_A	0.729	0.81
101_P	104_R	0.729	0.81
4_V	308_V	0.728	0.81
49_V	53_V	0.726	0.81
363_F	367_R	0.726	0.81
9_S	97_M	0.725	0.81
269_I	304_A	0.724	0.81
90_M	136_S	0.723	0.81
154_L	160_A	0.723	0.81
136_S	250_A	0.721	0.81
48_T	132_G	0.720	0.80
135_G	193_D	0.718	0.80
68_P	73_V	0.716	0.80
22_A	363_F	0.716	0.80
305_P	309_A	0.716	0.80
112_F	147_Q	0.715	0.80
156_A	170_R	0.709	0.79
306_L	336_Y	0.709	0.79
120_H	123_D	0.709	0.79
206_A	223_E	0.708	0.79
71_E	100_A	0.705	0.79
247_G	255_I	0.705	0.79
23_I	362_L	0.702	0.79
211_Q	303_K	0.700	0.79
155_D	161_L	0.699	0.78
352_A	356_A	0.696	0.78
66_C	72_K	0.695	0.78
287_L	373_I	0.694	0.78
266_K	271_I	0.694	0.78
209_G	223_E	0.690	0.78
329_G	332_V	0.689	0.77
153_F	174_I	0.688	0.77
53_V	58_G	0.684	0.77
20_C	23_I	0.683	0.77
161_L	225_G	0.683	0.77
4_V	39_L	0.683	0.77
351_L	355_L	0.683	0.77
141_G	226_L	0.682	0.77
165_G	214_A	0.680	0.77
232_V	236_Q	0.679	0.76
343_S	346_P	0.679	0.76
297_S	327_G	0.676	0.76
223_E	227_Q	0.673	0.76
225_G	228_N	0.668	0.75
48_T	272_V	0.667	0.75
322_I	362_L	0.665	0.75
179_C	183_L	0.662	0.75
59_N	124_N	0.659	0.74
16_A	20_C	0.657	0.74
334_H	368_N	0.657	0.74
344_I	361_N	0.656	0.74
223_E	226_L	0.656	0.74
171_V	229_Y	0.655	0.74
73_V	98_L	0.654	0.74
145_M	257_A	0.654	0.74
348_L	361_N	0.652	0.73
129_I	257_A	0.649	0.73
176_M	237_T	0.648	0.73
29_T	364_N	0.648	0.73
171_V	225_G	0.647	0.73
118_I	183_L	0.646	0.73
68_P	94_S	0.645	0.73
86_A	126_I	0.645	0.73
166_G	169_A	0.640	0.72
80_T	85_T	0.639	0.72
71_E	99_V	0.637	0.72
330_V	334_H	0.634	0.71
208_F	301_G	0.633	0.71
201_A	206_A	0.631	0.71
106_P	218_M	0.630	0.71
109_A	165_G	0.629	0.71
365_S	369_I	0.628	0.71
106_P	139_V	0.624	0.70
94_S	137_A	0.623	0.70
90_M	114_T	0.623	0.70
321_G	326_L	0.620	0.70
360_T	364_N	0.619	0.70
200_G	203_G	0.619	0.70
15_S	19_C	0.617	0.69
327_G	331_E	0.616	0.69
348_L	351_L	0.616	0.69
282_V	315_F	0.616	0.69
14_L	362_L	0.615	0.69
67_G	103_K	0.615	0.69
138_T	253_M	0.614	0.69
349_A	353_E	0.613	0.69
325_V	345_L	0.613	0.69
169_A	228_N	0.611	0.69
348_L	354_V	0.610	0.68
247_G	254_G	0.607	0.68
333_V	341_V	0.607	0.68
146_A	261_L	0.607	0.68
338_I	341_V	0.606	0.68
346_P	364_N	0.606	0.68
61_V	120_H	0.605	0.68
198_L	252_G	0.605	0.68
37_I	284_G	0.605	0.68
67_G	110_S	0.604	0.68
188_I	257_A	0.602	0.67
16_A	40_P	0.600	0.67
10_F	291_G	0.599	0.67
230_A	233_L	0.596	0.67
173_S	236_Q	0.596	0.67
366_A	369_I	0.595	0.67
233_L	241_V	0.594	0.66
110_S	138_T	0.593	0.66
287_L	320_I	0.593	0.66
365_S	368_N	0.592	0.66
99_V	109_A	0.589	0.66
94_S	111_S	0.587	0.66
141_G	233_L	0.586	0.65
27_F	31_F	0.586	0.65
216_P	219_V	0.586	0.65
241_V	259_V	0.585	0.65
278_L	308_V	0.584	0.65
63_L	67_G	0.584	0.65
205_A	222_L	0.583	0.65
135_G	194_V	0.583	0.65
126_I	186_C	0.582	0.65
212_K	303_K	0.582	0.65
199_V	205_A	0.582	0.65
59_N	79_L	0.581	0.65
221_E	224_Q	0.581	0.65
4_V	37_I	0.579	0.64
189_E	264_D	0.579	0.64
131_L	263_A	0.579	0.64
254_G	265_I	0.578	0.64
133_I	265_I	0.576	0.64
340_A	372_A	0.575	0.64
13_S	351_L	0.573	0.64
207_V	210_P	0.572	0.64
206_A	210_P	0.572	0.64
21_Q	24_K	0.571	0.63
320_I	369_I	0.570	0.63
116_E	148_A	0.569	0.63
228_N	231_R	0.568	0.63
220_E	224_Q	0.568	0.63
231_R	235_Q	0.567	0.63
48_T	87_V	0.566	0.63
36_Y	370_A	0.565	0.63
211_Q	298_Q	0.565	0.63
327_G	334_H	0.564	0.62
21_Q	25_A	0.563	0.62
145_M	256_A	0.563	0.62
141_G	168_L	0.563	0.62
295_I	338_I	0.563	0.62
146_A	153_F	0.562	0.62
208_F	211_Q	0.561	0.62
5_I	38_C	0.558	0.62
289_I	370_A	0.558	0.62
231_R	234_Q	0.558	0.62
114_T	117_L	0.555	0.61
3_I	27_F	0.555	0.61
176_M	236_Q	0.553	0.61
208_F	303_K	0.552	0.61
143_M	168_L	0.550	0.61
225_G	229_Y	0.549	0.60
300_A	306_L	0.548	0.60
26_G	366_A	0.547	0.60
317_V	339_D	0.545	0.60
193_D	250_A	0.544	0.60
49_V	60_I	0.544	0.60
244_M	255_I	0.543	0.60
250_A	268_G	0.543	0.60
49_V	88_I	0.542	0.59
133_I	208_F	0.541	0.59
146_A	257_A	0.541	0.59
143_M	225_G	0.540	0.59
345_L	348_L	0.540	0.59
67_G	116_E	0.539	0.59
292_E	303_K	0.539	0.59
370_A	373_I	0.537	0.59
266_K	270_E	0.536	0.59
9_S	298_Q	0.535	0.58
114_T	137_A	0.534	0.58
109_A	214_A	0.533	0.58
348_L	372_A	0.533	0.58
109_A	139_V	0.532	0.58
183_L	186_C	0.532	0.58
224_Q	227_Q	0.529	0.58
147_Q	162_A	0.528	0.57
11_K	46_E	0.528	0.57
145_M	254_G	0.528	0.57
88_I	131_L	0.525	0.57
62_T	75_A	0.525	0.57
66_C	73_V	0.525	0.57
193_D	268_G	0.525	0.57
322_I	365_S	0.525	0.57
278_L	282_V	0.523	0.57
255_I	258_A	0.523	0.57
116_E	119_R	0.522	0.57
161_L	172_A	0.522	0.57
16_A	308_V	0.520	0.56
288_V	317_V	0.520	0.56
135_G	268_G	0.520	0.56
26_G	363_F	0.519	0.56
344_I	362_L	0.519	0.56
18_K	21_Q	0.518	0.56
151_V	175_E	0.518	0.56
297_S	300_A	0.518	0.56
66_C	163_A	0.518	0.56
320_I	372_A	0.518	0.56
99_V	104_R	0.516	0.56
122_L	181_P	0.513	0.55
344_I	365_S	0.512	0.55
114_T	145_M	0.511	0.55
5_I	27_F	0.510	0.55
181_P	185_N	0.510	0.55
167_N	225_G	0.510	0.55
86_A	129_I	0.510	0.55
189_E	271_I	0.509	0.55
133_I	192_C	0.509	0.55
242_C	247_G	0.508	0.55
39_L	278_L	0.507	0.54
323_A	341_V	0.506	0.54
114_T	131_L	0.506	0.54
143_M	163_A	0.505	0.54
310_S	336_Y	0.505	0.54
345_L	349_A	0.504	0.54
147_Q	167_N	0.504	0.54
68_P	137_A	0.502	0.54
355_L	358_G	0.501	0.54
133_I	253_M	0.501	0.54
270_E	311_V	0.500	0.53
13_S	361_N	0.500	0.53

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cwcA	2	0.979	100	0	Contact Map
1to6A	4	0.9738	100	0.028	Contact Map
2r751	1	0.4698	89.8	0.959	Contact Map
1vimA	4	0.4436	68.3	0.967	Contact Map
3jx9A	2	0.4016	61.4	0.969	Contact Map
2xz9A	2	0.6929	60.7	0.969	Contact Map
1rq2A	2	0.4593	57.4	0.969	Contact Map
4h2dA	1	0.3753	53.3	0.97	Contact Map
1x92A	4	0.4514	51.6	0.97	Contact Map
4hb7A	2	0.5381	48.9	0.971	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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