GREMLIN Database
YDIS - Probable electron transfer flavoprotein-quinone oxidoreductase YdiS
UniProt: P77337 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13978
Length: 429 (353)
Sequences: 26708 (20392)
Seq/√Len: 1085.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
32_L126_I4.1691.00
36_R130_R3.5871.00
16_A320_A3.4891.00
9_I153_A3.4401.00
349_K353_E3.2891.00
7_D30_D3.2511.00
7_D154_N3.2061.00
130_R147_G2.8101.00
6_F32_L2.7841.00
133_A169_S2.6861.00
129_V148_D2.6771.00
117_Q120_Q2.6331.00
133_A145_Q2.6271.00
20_A157_I2.5931.00
145_Q150_I2.5751.00
9_I144_V2.5411.00
34_I151_L2.5381.00
142_T152_E2.5181.00
23_V328_A2.4931.00
66_A116_E2.3781.00
9_I34_I2.3671.00
27_A332_I2.3471.00
132_D147_G2.3211.00
112_P116_E2.2841.00
16_A300_V2.1671.00
135_V145_Q2.0931.00
19_V321_I2.0681.00
126_I129_V2.0631.00
135_V142_T2.0591.00
142_T150_I2.0501.00
129_V146_A2.0411.00
146_A151_L2.0201.00
158_L166_L2.0081.00
34_I146_A1.9661.00
330_T351_E1.9631.00
140_K152_E1.9521.00
250_S253_Q1.9481.00
129_V149_D1.9381.00
137_E142_T1.9361.00
8_A29_L1.8871.00
131_V144_V1.8731.00
293_V346_A1.8701.00
59_I64_V1.8651.00
22_L117_Q1.8631.00
117_Q121_A1.8521.00
330_T347_Q1.8511.00
66_A117_Q1.8251.00
146_A149_D1.8161.00
159_A300_V1.8031.00
38_D128_G1.7971.00
30_D124_Q1.7931.00
8_A24_M1.7751.00
190_G272_K1.7501.00
7_D32_L1.7421.00
57_A325_Q1.7411.00
291_Q294_N1.7301.00
158_L299_I1.7191.00
293_V298_M1.7181.00
353_E358_M1.7181.00
54_T318_D1.7041.00
324_A328_A1.7031.00
126_I149_D1.6991.00
137_E152_E1.6861.00
134_L156_V1.5921.00
137_E140_K1.5861.00
65_S69_E1.5841.00
66_A120_Q1.5811.00
29_L332_I1.5761.00
115_M127_P1.5681.00
25_A123_A1.5651.00
118_A123_A1.5601.00
326_A330_T1.5531.00
136_R294_N1.5491.00
9_I151_L1.5451.00
66_A69_E1.5431.00
21_A33_V1.5341.00
326_A351_E1.5271.00
155_V345_L1.5201.00
329_T351_E1.5181.00
26_R121_A1.5141.00
292_L356_C1.5041.00
252_P256_E1.4931.00
170_L297_V1.4891.00
60_P325_Q1.4831.00
165_M169_S1.4821.00
160_D164_S1.4811.00
32_L151_L1.4781.00
298_M327_A1.4721.00
323_S352_L1.4701.00
20_A324_A1.4601.00
22_L26_R1.4581.00
115_M119_E1.4551.00
157_I300_V1.4461.00
291_Q349_K1.4401.00
251_V255_L1.4191.00
23_V61_G1.4141.00
279_H283_E1.4011.00
54_T321_I1.4001.00
292_L349_K1.3961.00
322_A355_S1.3871.00
15_V317_M1.3631.00
262_P265_R1.3391.00
70_R109_R1.3361.00
25_A121_A1.3201.00
10_V20_A1.3051.00
11_V131_V1.3041.00
22_L118_A1.2841.00
116_E119_E1.2801.00
157_I298_M1.2711.00
330_T344_S1.2681.00
253_Q256_E1.2661.00
6_F9_I1.2581.00
131_V166_L1.2511.00
165_M168_R1.2471.00
126_I151_L1.2411.00
256_E259_K1.2401.00
64_V68_V1.2341.00
211_L214_G1.2311.00
278_A282_P1.2301.00
173_V290_P1.2301.00
305_G323_S1.2281.00
330_T333_A1.2261.00
109_R112_P1.2251.00
375_R382_R1.2151.00
20_A24_M1.2091.00
22_L121_A1.2031.00
40_A127_P1.2021.00
131_V134_L1.1991.00
175_A290_P1.1911.00
19_V61_G1.1901.00
13_A18_S1.1881.00
375_R381_P1.1871.00
32_L124_Q1.1861.00
11_V160_D1.1811.00
9_I32_L1.1781.00
144_V153_A1.1781.00
153_A156_V1.1721.00
135_V150_I1.1691.00
293_V349_K1.1631.00
136_R296_G1.1601.00
279_H282_P1.1451.00
134_L169_S1.1441.00
45_M48_G1.1431.00
187_E190_G1.1401.00
7_D29_L1.1301.00
266_P269_S1.1301.00
20_A300_V1.1271.00
11_V166_L1.1271.00
162_V306_F1.1201.00
106_L109_R1.1191.00
280_M283_E1.1191.00
65_S68_V1.1091.00
136_R141_V1.0971.00
81_T84_S1.0961.00
358_M362_Q1.0921.00
278_A281_V1.0761.00
81_T85_A1.0751.00
190_G232_S1.0731.00
10_V21_A1.0721.00
378_S382_R1.0711.00
26_R117_Q1.0671.00
132_D145_Q1.0561.00
134_L170_L1.0561.00
243_D246_H1.0511.00
19_V23_V1.0461.00
294_N297_V1.0461.00
33_V125_F1.0451.00
21_A31_V1.0451.00
293_V342_A1.0441.00
34_I126_I1.0431.00
252_P255_L1.0421.00
10_V31_V1.0391.00
115_M125_F1.0361.00
225_F236_G1.0351.00
48_G317_M1.0311.00
31_V123_A1.0311.00
66_A113_W1.0301.00
60_P329_T1.0261.00
308_L319_L1.0261.00
347_Q350_R1.0171.00
86_V89_D1.0151.00
278_A283_E1.0151.00
300_V348_Y1.0121.00
191_L194_E1.0111.00
11_V156_V1.0011.00
375_R378_S0.9931.00
58_I63_A0.9881.00
346_A350_R0.9861.00
257_D260_Q0.9861.00
299_I303_A0.9851.00
6_F30_D0.9851.00
374_P377_F0.9821.00
34_I129_V0.9811.00
141_V156_V0.9801.00
18_S118_A0.9781.00
6_F124_Q0.9761.00
63_A117_Q0.9741.00
25_A122_G0.9721.00
309_N312_F0.9711.00
289_V299_I0.9571.00
283_E365_R0.9561.00
142_T145_Q0.9551.00
265_R269_S0.9491.00
116_E120_Q0.9461.00
56_E59_I0.9411.00
35_E127_P0.9391.00
22_L61_G0.9341.00
40_A115_M0.9331.00
144_V156_V0.9301.00
326_A329_T0.9231.00
55_L64_V0.9231.00
141_V296_G0.9221.00
333_A347_Q0.9211.00
71_K103_Y0.9211.00
63_A113_W0.9161.00
53_H315_R0.9111.00
131_V165_M0.9091.00
87_T90_F0.9061.00
253_Q257_D0.9041.00
66_A70_R0.9021.00
13_A35_E0.8971.00
109_R229_N0.8971.00
298_M348_Y0.8961.00
70_R112_P0.8951.00
70_R113_W0.8871.00
15_V321_I0.8811.00
187_E235_L0.8811.00
48_G107_R0.8811.00
308_L361_M0.8801.00
131_V169_S0.8781.00
53_H322_A0.8771.00
113_W116_E0.8751.00
18_S115_M0.8741.00
263_A266_P0.8731.00
365_R369_A0.8701.00
158_L297_V0.8691.00
32_L153_A0.8681.00
271_G274_L0.8641.00
188_V191_L0.8641.00
113_W117_Q0.8621.00
29_L335_K0.8581.00
7_D153_A0.8561.00
28_G31_V0.8561.00
23_V27_A0.8541.00
119_E124_Q0.8511.00
172_M289_V0.8491.00
375_R379_Q0.8461.00
55_L103_Y0.8451.00
293_V345_L0.8441.00
25_A31_V0.8321.00
207_G211_L0.8311.00
134_L166_L0.8311.00
255_L259_K0.8281.00
374_P381_P0.8271.00
262_P266_P0.8221.00
134_L297_V0.8221.00
254_M258_F0.8191.00
292_L353_E0.8161.00
34_I153_A0.8141.00
39_S127_P0.8081.00
164_S167_G0.8071.00
136_R295_E0.8061.00
67_P113_W0.8051.00
49_R102_S0.8041.00
24_M29_L0.8031.00
342_A346_A0.8031.00
25_A119_E0.8031.00
347_Q351_E0.8021.00
23_V26_R0.7971.00
59_I68_V0.7951.00
166_L297_V0.7921.00
25_A118_A0.7851.00
317_M321_I0.7821.00
158_L170_L0.7801.00
268_I271_G0.7781.00
53_H56_E0.7771.00
18_S111_D0.7751.00
111_D115_M0.7701.00
7_D151_L0.7701.00
54_T57_A0.7691.00
118_A122_G0.7661.00
256_E260_Q0.7661.00
308_L313_T0.7621.00
49_R104_T0.7611.00
209_A214_G0.7601.00
76_K208_A0.7601.00
208_A211_L0.7561.00
24_M331_V0.7541.00
299_I304_A0.7531.00
340_F344_S0.7521.00
172_M294_N0.7521.00
255_L269_S0.7511.00
292_L304_A0.7511.00
255_L258_F0.7511.00
119_E122_G0.7511.00
266_P270_G0.7451.00
351_E354_Q0.7451.00
374_P378_S0.7431.00
234_S238_V0.7421.00
155_V298_M0.7421.00
190_G193_P0.7401.00
55_L59_I0.7391.00
58_I321_I0.7371.00
34_I144_V0.7361.00
53_H355_S0.7341.00
157_I327_A0.7301.00
328_A332_I0.7301.00
76_K89_D0.7301.00
191_L195_Q0.7281.00
295_E342_A0.7231.00
245_A249_K0.7221.00
192_T195_Q0.7191.00
21_A123_A0.7161.00
333_A338_A0.7161.00
354_Q359_R0.7141.00
190_G231_D0.7141.00
8_A155_V0.7131.00
376_L379_Q0.7121.00
107_R111_D0.7111.00
105_V110_L0.7091.00
118_A121_A0.7091.00
332_I336_E0.7081.00
229_N232_S0.7041.00
313_T364_F0.7031.00
334_A337_R0.6991.00
275_E278_A0.6981.00
19_V114_L0.6971.00
325_Q329_T0.6971.00
130_R165_M0.6921.00
251_V258_F0.6911.00
82_E85_A0.6901.00
23_V57_A0.6901.00
67_P110_L0.6871.00
337_R341_S0.6871.00
207_G212_F0.6861.00
245_A248_Q0.6861.00
21_A118_A0.6861.00
24_M328_A0.6841.00
317_M320_A0.6791.00
334_A347_Q0.6791.00
25_A124_Q0.6791.00
288_M353_E0.6791.00
377_F380_Y0.6781.00
84_S87_T0.6771.00
319_L356_C0.6761.00
265_R270_G0.6741.00
31_V118_A0.6731.00
273_L276_Y0.6681.00
298_M345_L0.6681.00
319_L360_D0.6671.00
378_S381_P0.6661.00
20_A328_A0.6631.00
167_G299_I0.6621.00
334_A338_A0.6601.00
51_Y318_D0.6601.00
289_V292_L0.6581.00
170_L294_N0.6551.00
27_A328_A0.6551.00
89_D92_R0.6541.00
158_L164_S0.6541.00
191_L233_I0.6531.00
207_G210_W0.6521.00
315_R319_L0.6521.00
78_S86_V0.6511.00
210_W213_A0.6511.00
306_F323_S0.6511.00
118_A125_F0.6481.00
377_F381_P0.6471.00
40_A111_D0.6471.00
46_T107_R0.6461.00
129_V147_G0.6451.00
140_K154_N0.6441.00
18_S125_F0.6421.00
209_A212_F0.6421.00
343_S347_Q0.6401.00
13_A40_A0.6391.00
271_G275_E0.6381.00
171_G174_P0.6371.00
341_S344_S0.6361.00
179_H183_V0.6361.00
208_A212_F0.6351.00
106_L229_N0.6351.00
359_R362_Q0.6341.00
59_I65_S0.6301.00
234_S239_C0.6301.00
288_M358_M0.6271.00
259_K265_R0.6261.00
23_V325_Q0.6251.00
350_R354_Q0.6241.00
39_S42_C0.6231.00
139_N296_G0.6231.00
249_K253_Q0.6221.00
244_I249_K0.6181.00
288_M292_L0.6151.00
235_L239_C0.6151.00
329_T333_A0.6151.00
86_V90_F0.6141.00
158_L165_M0.6141.00
155_V335_K0.6121.00
346_A349_K0.6121.00
68_V71_K0.6091.00
22_L25_A0.6081.00
315_R318_D0.6071.00
363_H367_I0.6071.00
267_L271_G0.6051.00
364_F368_P0.6051.00
222_G257_D0.6031.00
134_L141_V0.6011.00
18_S33_V0.6001.00
16_A157_I0.5991.00
334_A343_S0.5971.00
187_E191_L0.5961.00
267_L270_G0.5961.00
58_I67_P0.5951.00
206_E209_A0.5951.00
166_L169_S0.5951.00
233_I236_G0.5951.00
70_R105_V0.5941.00
155_V331_V0.5881.00
235_L238_V0.5881.00
264_I267_L0.5861.00
8_A20_A0.5861.00
305_G352_L0.5851.00
20_A159_A0.5841.00
181_Y184_G0.5841.00
22_L63_A0.5801.00
22_L123_A0.5781.00
334_A344_S0.5781.00
367_I370_L0.5771.00
223_G227_Y0.5761.00
156_V296_G0.5761.00
338_A341_S0.5741.00
340_F343_S0.5731.00
374_P382_R0.5731.00
254_M257_D0.5721.00
356_C361_M0.5721.00
272_K275_E0.5711.00
376_L380_Y0.5701.00
20_A331_V0.5691.00
300_V324_A0.5691.00
154_N335_K0.5671.00
182_A186_K0.5641.00
362_Q365_R0.5631.00
359_R363_H0.5601.00
58_I110_L0.5601.00
80_L85_A0.5581.00
156_V297_V0.5581.00
377_F382_R0.5571.00
190_G194_E0.5561.00
322_A326_A0.5561.00
338_A342_A0.5551.00
57_A61_G0.5531.00
138_G141_V0.5531.00
227_Y236_G0.5511.00
337_R340_F0.5511.00
168_R173_V0.5501.00
305_G356_C0.5501.00
335_K338_A0.5491.00
50_L54_T0.5471.00
184_G187_E0.5471.00
270_G273_L0.5461.00
51_Y54_T0.5461.00
322_A352_L0.5451.00
224_G228_T0.5431.00
30_D154_N0.5421.00
187_E194_E0.5401.00
343_S346_A0.5391.00
374_P379_Q0.5381.00
29_L331_V0.5381.00
71_K74_R0.5371.00
312_F368_P0.5341.00
264_I268_I0.5341.00
244_I248_Q0.5341.00
326_A348_Y0.5331.00
154_N296_G0.5331.00
67_P103_Y0.5331.00
366_K369_A0.5321.00
326_A352_L0.5321.00
174_P287_A0.5311.00
46_T227_Y0.5311.00
206_E212_F0.5301.00
119_E127_P0.5301.00
38_D127_P0.5291.00
315_R360_D0.5251.00
156_V166_L0.5251.00
155_V334_A0.5241.00
302_D320_A0.5241.00
78_S89_D0.5241.00
128_G148_D0.5231.00
13_A33_V0.5231.00
364_F367_I0.5221.00
309_N313_T0.5201.00
180_H183_V0.5201.00
210_W214_G0.5201.00
368_P372_E0.5191.00
157_I331_V0.5191.00
363_H366_K0.5181.00
283_E286_L0.5181.00
59_I100_H0.5181.00
57_A60_P0.5181.00
333_A337_R0.5171.00
88_L92_R0.5171.00
10_V17_G0.5161.00
37_G41_G0.5151.00
181_Y185_V0.5151.00
313_T367_I0.5151.00
276_Y279_H0.5141.00
20_A23_V0.5131.00
64_V67_P0.5131.00
189_I192_T0.5121.00
11_V134_L0.5121.00
250_S254_M0.5121.00
131_V146_A0.5121.00
57_A322_A0.5111.00
6_F154_N0.5101.00
276_Y282_P0.5101.00
19_V57_A0.5091.00
177_D180_H0.5091.00
362_Q366_K0.5081.00
369_A373_N0.5081.00
31_V122_G0.5071.00
23_V324_A0.5061.00
178_P181_Y0.5061.00
163_N168_R0.5051.00
6_F151_L0.5051.00
78_S81_T0.5051.00
185_V188_V0.5031.00
193_P196_I0.5021.00
47_G234_S0.5021.00
56_E60_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pn0A 3 0.9301 100 0.378 Contact Map
2qa1A 2 0.8951 100 0.383 Contact Map
2qa2A 2 0.8998 100 0.388 Contact Map
2dkhA 2 0.9044 100 0.396 Contact Map
4k5sA 2 0.9044 100 0.399 Contact Map
3ihgA 3 0.9068 100 0.401 Contact Map
4bjzA 2 0.8904 100 0.402 Contact Map
4k22A 4 0.8019 100 0.403 Contact Map
2x3nA 1 0.8135 100 0.403 Contact Map
3c96A 1 0.8228 100 0.405 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.012 seconds.