GREMLIN Database
GMR - Cyclic di-GMP phosphodiesterase Gmr
UniProt: P77334 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13415
Length: 661 (549)
Sequences: 10904 (8735)
Seq/√Len: 372.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
439_L650_F4.7611.00
432_W636_R4.1131.00
477_L519_E3.9721.00
235_I239_T3.8731.00
584_Q588_R3.8211.00
642_A645_M3.7471.00
305_E308_Q3.7191.00
472_G503_Q3.6291.00
551_S578_D3.4291.00
405_E457_D3.4171.00
514_K553_L3.1971.00
423_V446_Q3.1671.00
473_R512_A3.0241.00
619_V636_R2.9621.00
426_Y482_Q2.8471.00
122_S221_T2.8171.00
622_A626_A2.6871.00
608_Q634_N2.6471.00
573_A596_S2.6471.00
484_A488_D2.6411.00
369_D372_A2.5891.00
447_S451_G2.5661.00
251_M319_L2.5321.00
270_V358_V2.5321.00
412_N447_S2.4921.00
487_R526_P2.4221.00
627_F631_N2.4171.00
462_A471_L2.4161.00
478_D481_R2.4081.00
516_V520_L2.4041.00
125_V218_C2.2941.00
425_H646_P2.2221.00
443_V475_V2.2221.00
528_D579_A2.2051.00
482_Q486_W2.1891.00
558_H579_A2.1511.00
482_Q647_A2.1411.00
499_I509_I2.1331.00
447_S450_R2.0511.00
270_V334_A2.0451.00
422_L443_V2.0291.00
364_P367_G2.0271.00
146_L192_C1.9941.00
430_I641_F1.9521.00
625_D636_R1.9511.00
483_V522_F1.9491.00
625_D641_F1.8991.00
424_I474_W1.8801.00
547_I557_V1.8761.00
474_W478_D1.8741.00
200_F221_T1.8671.00
123_A143_Y1.8611.00
639_F644_P1.8501.00
295_D298_L1.8481.00
423_V452_L1.8381.00
191_T195_Q1.8331.00
117_V135_R1.8251.00
295_D345_F1.8221.00
268_G362_L1.8211.00
226_E230_Q1.8181.00
123_A220_G1.8131.00
480_V516_V1.8121.00
477_L520_L1.7961.00
128_D132_N1.7951.00
446_Q452_L1.7931.00
478_D482_Q1.7771.00
424_I475_V1.7721.00
276_N389_R1.7621.00
601_R609_A1.7591.00
604_V631_N1.7531.00
150_D192_C1.7461.00
486_W647_A1.7311.00
646_P649_A1.7191.00
429_K528_D1.7151.00
275_D357_S1.7131.00
291_Q294_R1.7101.00
421_Q447_S1.6901.00
246_P250_A1.6881.00
443_V471_L1.6831.00
254_L309_V1.6731.00
420_D478_D1.6641.00
255_I370_S1.6641.00
591_H623_K1.6631.00
429_K438_S1.6551.00
597_Q627_F1.6531.00
125_V133_I1.6451.00
425_H452_L1.6421.00
494_R556_Q1.6391.00
138_R142_D1.6261.00
208_G212_N1.6251.00
523_E526_P1.6241.00
227_R230_Q1.6211.00
613_Q634_N1.6171.00
367_G376_H1.6161.00
591_H627_F1.6131.00
429_K635_E1.6051.00
291_Q348_G1.6021.00
591_H597_Q1.5981.00
186_E227_R1.5951.00
622_A640_L1.5871.00
601_R631_N1.5731.00
304_L310_L1.5691.00
250_A254_L1.5671.00
573_A589_D1.5551.00
322_A333_M1.5531.00
625_D640_L1.5521.00
387_G393_C1.5331.00
448_P451_G1.5211.00
334_A360_I1.5191.00
406_Y464_E1.5091.00
625_D629_T1.5071.00
436_V653_W1.5001.00
424_I479_V1.4981.00
412_N450_R1.4961.00
621_S624_E1.4931.00
559_L577_I1.4911.00
272_L356_C1.4901.00
281_N289_G1.4881.00
384_A393_C1.4701.00
450_R457_D1.4661.00
487_R523_E1.4651.00
613_Q635_E1.4601.00
513_L550_F1.4591.00
200_F226_E1.4521.00
415_K419_N1.4481.00
556_Q578_D1.4451.00
443_V474_W1.4401.00
188_W198_F1.4381.00
501_A534_S1.4371.00
579_A615_I1.4321.00
429_K579_A1.4251.00
225_E228_R1.4251.00
110_L114_E1.4091.00
205_V213_E1.4061.00
645_M653_W1.4031.00
139_L142_D1.4021.00
477_L516_V1.3961.00
298_L301_L1.3921.00
604_V633_I1.3921.00
483_V495_V1.3891.00
120_A124_I1.3801.00
335_S339_T1.3781.00
326_S329_A1.3671.00
499_I529_V1.3651.00
292_L354_T1.3631.00
355_S390_G1.3621.00
517_L555_A1.3551.00
409_L461_Y1.3531.00
346_R351_E1.3451.00
590_I627_F1.3391.00
636_R641_F1.3351.00
341_L356_C1.3331.00
274_L296_V1.3321.00
232_R236_L1.3291.00
486_W651_E1.3281.00
415_K421_Q1.3191.00
489_K651_E1.3161.00
514_K549_Q1.3021.00
235_I244_G1.2951.00
161_M164_R1.2901.00
286_H378_D1.2891.00
239_T250_A1.2831.00
232_R235_I1.2801.00
580_I607_A1.2801.00
577_I612_L1.2761.00
649_A652_R1.2741.00
254_L257_H1.2651.00
528_D558_H1.2611.00
268_G330_L1.2591.00
266_K365_E1.2581.00
366_H394_V1.2551.00
276_N410_D1.2511.00
164_R188_W1.2471.00
191_T197_L1.2471.00
494_R528_D1.2471.00
154_Q158_K1.2431.00
331_E394_V1.2421.00
421_Q445_W1.2421.00
341_L345_F1.2381.00
251_M321_L1.2361.00
447_S453_I1.2361.00
383_T386_E1.2351.00
113_A117_V1.2301.00
437_R635_E1.2211.00
424_I443_V1.2201.00
271_Y381_M1.2181.00
123_A137_N1.2171.00
125_V140_C1.2161.00
384_A391_Q1.2161.00
250_A309_V1.2111.00
296_V341_L1.2101.00
626_A630_K1.2091.00
126_I215_F1.1981.00
261_H323_S1.1961.00
590_I600_V1.1931.00
292_L345_F1.1921.00
421_Q448_P1.1841.00
230_Q234_R1.1801.00
456_L584_Q1.1791.00
184_E200_F1.1751.00
422_L474_W1.1731.00
287_L371_T1.1721.00
601_R605_A1.1711.00
479_V495_V1.1701.00
413_L422_L1.1681.00
114_E118_S1.1651.00
188_W196_R1.1601.00
579_A613_Q1.1601.00
279_K410_D1.1591.00
251_M311_A1.1571.00
515_Q519_E1.1521.00
505_A538_E1.1401.00
431_T435_E1.1401.00
602_A609_A1.1401.00
450_R453_I1.1391.00
432_W625_D1.1391.00
593_Q596_S1.1361.00
383_T393_C1.1351.00
330_L334_A1.1341.00
117_V124_I1.1311.00
342_R390_G1.1281.00
527_I555_A1.1221.00
616_A633_I1.1191.00
288_F350_I1.1161.00
429_K496_A1.1151.00
351_E415_K1.1151.00
274_L356_C1.1151.00
607_A614_V1.1091.00
331_E335_S1.1071.00
338_L392_F1.1071.00
485_K489_K1.1071.00
278_K382_Y1.1061.00
459_I468_I1.1041.00
480_V527_I1.1031.00
584_Q618_G1.1021.00
228_R232_R1.1011.00
346_R349_L1.1011.00
540_D575_F1.0961.00
360_I394_V1.0961.00
189_I199_L1.0951.00
315_G382_Y1.0931.00
626_A629_T1.0921.00
579_A635_E1.0911.00
207_S213_E1.0881.00
512_A516_V1.0871.00
291_Q295_D1.0771.00
147_K150_D1.0721.00
482_Q485_K1.0701.00
379_T399_M1.0691.00
295_D299_A1.0681.00
642_A653_W1.0671.00
164_R168_A1.0661.00
476_I516_V1.0641.00
140_C144_T1.0631.00
113_A116_V1.0621.00
544_L548_Q1.0571.00
465_S469_V1.0531.00
510_F546_V1.0471.00
271_Y319_L1.0451.00
492_N526_P1.0441.00
482_Q651_E1.0411.00
429_K494_R1.0411.00
273_D385_K1.0371.00
497_V527_I1.0361.00
347_I352_V1.0311.00
146_L150_D1.0301.00
317_E378_D1.0241.00
276_N279_K1.0221.00
127_L218_C1.0191.00
455_P458_F1.0181.00
496_A528_D1.0181.00
528_D556_Q1.0171.00
256_D370_S1.0121.00
378_D382_Y1.0111.00
361_A376_H1.0111.00
126_I217_I1.0051.00
363_S373_I1.0031.00
250_A253_D1.0021.00
198_F223_I1.0011.00
132_N155_S1.0011.00
238_N249_N0.9971.00
483_V487_R0.9961.00
510_F514_K0.9951.00
284_Y350_I0.9941.00
231_E234_R0.9931.00
405_E450_R0.9921.00
275_D389_R0.9901.00
412_N449_E0.9901.00
360_I392_F0.9881.00
484_A487_R0.9871.00
376_H400_N0.9871.00
465_S468_I0.9841.00
463_E468_I0.9801.00
258_A267_V0.9791.00
372_A376_H0.9791.00
141_E148_E0.9781.00
509_I513_L0.9771.00
109_G112_F0.9761.00
481_R485_K0.9751.00
423_V646_P0.9741.00
517_L522_F0.9741.00
136_F141_E0.9731.00
303_C337_I0.9721.00
481_R520_L0.9691.00
277_F293_L0.9671.00
300_I310_L0.9671.00
544_L574_R0.9671.00
187_L201_R0.9661.00
477_L481_R0.9651.00
619_V628_L0.9651.00
313_P319_L0.9651.00
420_D477_L0.9611.00
106_L110_L0.9611.00
135_R148_E0.9601.00
430_I436_V0.9591.00
608_Q614_V0.9591.00
198_F224_T0.9571.00
299_A344_P0.9571.00
267_V363_S0.9561.00
338_L358_V0.9541.00
484_A520_L0.9511.00
388_G391_Q0.9511.00
256_D260_N0.9491.00
476_I513_L0.9481.00
479_V497_V0.9481.00
615_I635_E0.9471.00
410_D414_R0.9471.00
645_M649_A0.9411.00
470_P473_R0.9391.00
441_A495_V0.9371.00
254_L311_A0.9331.00
297_S310_L0.9331.00
340_R343_L0.9331.00
136_F140_C0.9321.00
314_G317_E0.9321.00
396_T399_M0.9321.00
262_A363_S0.9311.00
190_P196_R0.9291.00
547_I576_P0.9291.00
467_L470_P0.9281.00
229_A233_L0.9271.00
275_D388_G0.9251.00
513_L529_V0.9241.00
604_V608_Q0.9201.00
453_I460_S0.9191.00
426_Y441_A0.9191.00
561_D617_E0.9181.00
133_I218_C0.9161.00
305_E336_R0.9151.00
299_A345_F0.9141.00
549_Q552_Q0.9131.00
273_D382_Y0.9111.00
127_L133_I0.9091.00
136_F151_V0.9081.00
429_K615_I0.9081.00
124_I219_S0.9061.00
141_E147_K0.9051.00
148_E152_I0.9031.00
273_D316_D0.9031.00
305_E333_M0.9031.00
203_K216_L0.9031.00
252_Q371_T0.9031.00
240_D312_R0.9021.00
622_A625_D0.8981.00
282_D382_Y0.8981.00
540_D543_A0.8971.00
233_L236_L0.8951.00
438_S494_R0.8911.00
280_V292_L0.8901.00
320_V337_I0.8891.00
548_Q552_Q0.8851.00
138_R141_E0.8821.00
484_A521_N0.8811.00
383_T387_G0.8751.00
446_Q451_G0.8741.00
270_V322_A0.8741.00
469_V506_D0.8731.00
431_T634_N0.8731.00
175_V179_S0.8711.00
241_S249_N0.8701.00
189_I197_L0.8681.00
118_S138_R0.8651.00
155_S158_K0.8631.00
517_L524_Y0.8621.00
510_F549_Q0.8591.00
333_M336_R0.8581.00
304_L320_V0.8571.00
413_L462_A0.8561.00
397_P401_Q0.8561.00
335_S338_L0.8541.00
334_A392_F0.8541.00
265_N324_N0.8531.00
431_T437_R0.8521.00
234_R238_N0.8511.00
275_D355_S0.8471.00
199_L220_G0.8471.00
123_A139_L0.8461.00
413_L416_A0.8441.00
203_K218_C0.8431.00
573_A593_Q0.8401.00
532_T561_D0.8381.00
434_G629_T0.8371.00
425_H446_Q0.8371.00
331_E392_F0.8311.00
205_V215_F0.8311.00
416_A422_L0.8251.00
259_I363_S0.8231.00
163_R188_W0.8221.00
255_I321_L0.8211.00
513_L516_V0.8211.00
480_V522_F0.8211.00
408_W412_N0.8211.00
294_R298_L0.8171.00
462_A466_G0.8131.00
511_T549_Q0.8121.00
201_R220_G0.8121.00
276_N464_E0.8111.00
206_H215_F0.8091.00
599_L606_V0.8091.00
278_K282_D0.8091.00
647_A651_E0.8081.00
253_D257_H0.8081.00
542_L546_V0.8081.00
288_F291_Q0.8071.00
322_A330_L0.8061.00
246_P309_V0.8051.00
486_W650_F0.8051.00
258_A323_S0.8031.00
272_L320_V0.8011.00
201_R218_C0.8011.00
357_S389_R0.8001.00
480_V520_L0.8001.00
430_I653_W0.7991.00
223_I227_R0.7981.00
304_L308_Q0.7981.00
423_V648_V0.7981.00
128_D134_Q0.7971.00
270_V320_V0.7961.00
273_D281_N0.7951.00
107_S110_L0.7941.00
296_V345_F0.7941.00
473_R515_Q0.7931.00
494_R526_P0.7921.00
286_H382_Y0.7881.00
186_E200_F0.7881.00
522_F527_I0.7871.00
418_E470_P0.7861.00
539_N542_L0.7851.00
238_N253_D0.7821.00
387_G391_Q0.7821.00
138_R148_E0.7821.00
116_V217_I0.7811.00
504_L535_C0.7811.00
511_T515_Q0.7811.00
161_M196_R0.7801.00
362_L394_V0.7781.00
556_Q613_Q0.7781.00
257_H323_S0.7781.00
339_T342_R0.7771.00
106_L109_G0.7761.00
253_D309_V0.7761.00
292_L347_I0.7751.00
310_L320_V0.7751.00
439_L495_V0.7741.00
281_N315_G0.7741.00
473_R477_L0.7741.00
516_V519_E0.7731.00
372_A375_R0.7711.00
126_I137_N0.7671.00
281_N290_D0.7661.00
319_L374_I0.7661.00
439_L493_L0.7661.00
224_T228_R0.7651.00
514_K518_Q0.7651.00
134_Q215_F0.7621.00
506_D512_A0.7601.00
415_K418_E0.7601.00
251_M255_I0.7581.00
334_A338_L0.7581.00
364_P376_H0.7571.00
140_C151_V0.7571.00
513_L555_A0.7551.00
564_T586_F0.7541.00
395_F400_N0.7531.00
288_F352_V0.7521.00
400_N404_F0.7491.00
267_V373_I0.7481.00
530_E581_K0.7461.00
551_S557_V0.7461.00
587_V600_V0.7451.00
111_S115_Q0.7441.00
430_I434_G0.7441.00
288_F347_I0.7431.00
536_L571_Q0.7431.00
604_V628_L0.7431.00
316_D385_K0.7431.00
573_A599_L0.7411.00
508_T512_A0.7411.00
532_T617_E0.7401.00
259_I267_V0.7371.00
529_V557_V0.7371.00
226_E229_A0.7361.00
409_L412_N0.7341.00
271_Y313_P0.7341.00
416_A421_Q0.7321.00
499_I503_Q0.7281.00
442_L498_N0.7261.00
303_C336_R0.7251.00
338_L356_C0.7241.00
325_T330_L0.7231.00
483_V520_L0.7221.00
587_V616_A0.7211.00
282_D378_D0.7201.00
440_E498_N0.7191.00
129_S213_E0.7161.00
198_F227_R0.7161.00
117_V120_A0.7141.00
123_A140_C0.7141.00
264_N305_E0.7121.00
245_L297_S0.7121.00
262_A267_V0.7121.00
127_L156_V0.7111.00
529_V555_A0.7101.00
591_H624_E0.7101.00
105_D108_H0.7101.00
136_F148_E0.7090.99
122_S139_L0.7090.99
639_F643_K0.7080.99
517_L520_L0.7050.99
504_L546_V0.7040.99
353_Y414_R0.7010.99
420_D474_W0.7000.99
383_T402_R0.6980.99
303_C340_R0.6980.99
510_F553_L0.6970.99
476_I497_V0.6960.99
434_G622_A0.6960.99
302_S340_R0.6960.99
184_E202_N0.6950.99
127_L203_K0.6950.99
589_D592_K0.6930.99
401_Q405_E0.6890.99
160_F165_E0.6890.99
454_P460_S0.6890.99
598_S609_A0.6880.99
605_A608_Q0.6870.99
616_A628_L0.6870.99
160_F164_R0.6860.99
205_V216_L0.6860.99
112_F126_I0.6860.99
591_H621_S0.6850.99
116_V126_I0.6840.99
281_N385_K0.6830.99
183_Y203_K0.6830.99
469_V503_Q0.6820.99
267_V321_L0.6810.99
228_R231_E0.6810.99
645_M650_F0.6790.99
334_A358_V0.6770.99
597_Q631_N0.6770.99
589_D596_S0.6760.99
498_N581_K0.6760.99
280_V289_G0.6750.99
161_M188_W0.6740.99
117_V137_N0.6740.99
110_L113_A0.6740.99
582_L603_I0.6740.99
487_R490_G0.6730.99
329_A332_A0.6720.99
574_R595_V0.6710.99
330_L360_I0.6700.99
614_V634_N0.6700.99
308_Q336_R0.6700.99
548_Q576_P0.6680.99
571_Q574_R0.6670.99
441_A479_V0.6670.99
428_P642_A0.6670.99
127_L173_N0.6660.99
275_D385_K0.6650.99
459_I532_T0.6640.99
173_N203_K0.6630.99
275_D390_G0.6620.99
144_T189_I0.6610.99
124_I137_N0.6600.99
537_I571_Q0.6570.99
588_R624_E0.6540.99
181_N205_V0.6540.99
124_I135_R0.6540.99
284_Y352_V0.6530.99
395_F399_M0.6520.99
479_V483_V0.6510.99
330_L362_L0.6510.99
116_V119_E0.6510.99
459_I463_E0.6490.99
277_F281_N0.6460.99
628_L633_I0.6450.99
254_L258_A0.6430.99
338_L390_G0.6430.99
281_N316_D0.6420.99
446_Q450_R0.6400.99
507_Q542_L0.6390.99
641_F644_P0.6370.99
403_V407_L0.6370.99
125_V220_G0.6370.99
305_E325_T0.6370.99
287_L375_R0.6360.99
137_N140_C0.6360.99
363_S367_G0.6340.99
496_A579_A0.6330.99
590_I597_Q0.6330.99
445_W451_G0.6330.99
366_H376_H0.6320.99
332_A336_R0.6320.99
270_V360_I0.6300.99
229_A236_L0.6300.99
605_A609_A0.6300.99
314_G382_Y0.6280.99
485_K488_D0.6270.99
398_E402_R0.6260.99
186_E226_E0.6250.99
481_R519_E0.6250.99
235_I238_N0.6240.99
119_E217_I0.6210.99
233_L238_N0.6210.99
116_V120_A0.6200.99
546_V549_Q0.6200.99
471_L475_V0.6200.99
108_H112_F0.6200.99
462_A468_I0.6190.99
126_I135_R0.6190.99
127_L131_G0.6190.99
485_K651_E0.6180.99
229_A232_R0.6180.99
597_Q601_R0.6170.99
468_I502_R0.6160.99
414_R470_P0.6150.99
327_Q331_E0.6150.99
241_S244_G0.6140.99
473_R516_V0.6110.99
278_K378_D0.6110.99
483_V526_P0.6110.99
463_E500_S0.6100.98
511_T514_K0.6090.98
116_V121_H0.6090.98
161_M168_A0.6060.98
135_R138_R0.6050.98
476_I529_V0.6050.98
268_G360_I0.6030.98
301_L310_L0.6030.98
650_F653_W0.6020.98
570_S585_V0.6000.98
125_V203_K0.5990.98
286_H315_G0.5980.98
145_G191_T0.5960.98
121_H217_I0.5930.98
410_D465_S0.5930.98
545_S549_Q0.5930.98
564_T585_V0.5930.98
472_G475_V0.5890.98
540_D544_L0.5890.98
141_E151_V0.5890.98
495_V522_F0.5880.98
164_R187_L0.5880.98
604_V614_V0.5870.98
501_A571_Q0.5860.98
363_S366_H0.5850.98
121_H204_F0.5830.98
498_N560_D0.5830.98
443_V452_L0.5820.98
587_V590_I0.5810.98
604_V634_N0.5810.98
328_S331_E0.5810.98
580_I612_L0.5790.98
589_D593_Q0.5790.98
273_D277_F0.5790.98
426_Y439_L0.5780.98
162_S165_E0.5770.98
627_F630_K0.5770.98
204_F217_I0.5760.98
296_V300_I0.5760.98
345_F354_T0.5760.98
476_I555_A0.5750.98
357_S388_G0.5740.98
504_L547_I0.5740.98
508_T511_T0.5720.98
125_V136_F0.5720.98
569_L603_I0.5710.98
456_L460_S0.5710.98
277_F289_G0.5710.98
156_V218_C0.5710.98
483_V527_I0.5700.98
160_F168_A0.5690.98
127_L216_L0.5680.98
619_V625_D0.5680.98
440_E581_K0.5670.98
594_P597_Q0.5670.98
140_C220_G0.5660.98
368_S372_A0.5650.98
136_F144_T0.5620.97
398_E401_Q0.5620.97
512_A515_Q0.5610.97
107_S111_S0.5610.97
598_S601_R0.5610.97
417_L471_L0.5600.97
606_V610_L0.5600.97
501_A531_L0.5590.97
144_T220_G0.5590.97
515_Q518_Q0.5560.97
116_V124_I0.5550.97
545_S548_Q0.5550.97
277_F385_K0.5540.97
537_I543_A0.5540.97
238_N250_A0.5540.97
422_L462_A0.5530.97
424_I441_A0.5520.97
325_T329_A0.5520.97
550_F553_L0.5510.97
599_L603_I0.5500.97
453_I459_I0.5490.97
252_Q370_S0.5490.97
335_S392_F0.5490.97
339_T343_L0.5480.97
146_L159_L0.5460.97
544_L576_P0.5460.97
176_F216_L0.5450.97
423_V443_V0.5450.97
286_H289_G0.5450.97
284_Y288_F0.5450.97
105_D109_G0.5440.97
431_T635_E0.5420.97
559_L571_Q0.5410.97
435_E492_N0.5410.97
266_K325_T0.5400.97
504_L575_F0.5400.97
248_R317_E0.5400.97
109_G114_E0.5400.97
417_L474_W0.5380.97
359_G377_A0.5370.97
299_A343_L0.5370.97
650_F654_Y0.5360.97
113_A217_I0.5360.97
208_G214_I0.5360.97
434_G625_D0.5360.97
248_R290_D0.5350.97
424_I478_D0.5340.97
277_F316_D0.5340.97
530_E617_E0.5340.97
476_I499_I0.5340.97
473_R506_D0.5340.97
461_Y465_S0.5330.97
463_E532_T0.5330.97
504_L509_I0.5320.96
315_G378_D0.5310.96
485_K647_A0.5290.96
651_E654_Y0.5290.96
498_N639_F0.5290.96
126_I218_C0.5290.96
364_P373_I0.5290.96
408_W449_E0.5280.96
541_E574_R0.5280.96
282_D286_H0.5270.96
412_N445_W0.5260.96
438_S496_A0.5250.96
116_V122_S0.5250.96
200_F223_I0.5250.96
253_D256_D0.5250.96
532_T586_F0.5240.96
327_Q365_E0.5240.96
258_A262_A0.5240.96
412_N448_P0.5230.96
440_E560_D0.5220.96
454_P457_D0.5210.96
239_T246_P0.5210.96
443_V458_F0.5200.96
128_D131_G0.5190.96
225_E229_A0.5180.96
133_I137_N0.5170.96
596_S624_E0.5170.96
242_I294_R0.5170.96
119_E137_N0.5170.96
402_R405_E0.5160.96
426_Y478_D0.5150.96
163_R196_R0.5150.96
117_V126_I0.5150.96
428_P645_M0.5140.96
535_C571_Q0.5140.96
536_L559_L0.5120.96
355_S388_G0.5120.96
465_S470_P0.5120.96
629_T636_R0.5110.96
409_L445_W0.5110.96
582_L633_I0.5110.96
413_L445_W0.5100.96
359_G380_A0.5100.96
557_V577_I0.5100.96
287_L348_G0.5090.95
473_R503_Q0.5090.95
258_A309_V0.5090.95
268_G325_T0.5090.95
376_H395_F0.5080.95
206_H217_I0.5080.95
123_A199_L0.5080.95
442_L639_F0.5070.95
119_E122_S0.5070.95
414_R467_L0.5070.95
123_A217_I0.5070.95
258_A261_H0.5070.95
517_L553_L0.5060.95
273_D278_K0.5060.95
171_R175_V0.5040.95
133_I136_F0.5040.95
278_K281_N0.5030.95
536_L543_A0.5030.95
333_M337_I0.5030.95
428_P436_V0.5030.95
379_T403_V0.5020.95
338_L355_S0.5020.95
273_D289_G0.5020.95
289_G316_D0.5020.95
121_H221_T0.5020.95
146_L191_T0.5010.95
426_Y486_W0.5010.95
498_N530_E0.5010.95
274_L355_S0.5000.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rnhA 2 0.6263 100 0.359 Contact Map
4j40A 2 0.3782 100 0.365 Contact Map
3pjxA 1 0.6293 100 0.381 Contact Map
3gfzA 2 0.5688 100 0.469 Contact Map
4hjfA 1 0.3918 100 0.504 Contact Map
4hu4A 1 0.3707 100 0.58 Contact Map
3sy8A 6 0.5946 100 0.584 Contact Map
2r6oA 2 0.3858 100 0.584 Contact Map
4kieA 1 0.3918 100 0.584 Contact Map
4rniA 2 0.3812 100 0.589 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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