GREMLIN Database
HSCC - Chaperone protein HscC
UniProt: P77319 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13653
Length: 556 (524)
Sequences: 7395 (3827)
Seq/√Len: 167.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
116_D143_N5.1261.00
198_D278_R4.8751.00
209_M274_P4.4531.00
171_F279_L3.9371.00
210_L263_F3.6881.00
71_L204_E3.6091.00
217_R267_E3.5821.00
314_R318_R3.4711.00
317_V323_L3.3721.00
182_V286_A3.2131.00
378_S395_Y3.1291.00
32_N39_T3.0891.00
506_L509_L3.0371.00
36_E55_K2.9751.00
363_S379_P2.8711.00
406_T427_D2.7051.00
476_A480_E2.6481.00
379_P382_E2.6451.00
329_D332_T2.5971.00
194_A286_A2.5331.00
215_L224_T2.5011.00
408_N422_L2.4841.00
116_D145_V2.4401.00
313_Q326_Q2.4271.00
519_E523_R2.4221.00
267_E270_D2.3851.00
103_K107_E2.3641.00
365_G377_F2.3581.00
247_P262_E2.3551.00
173_L206_F2.3391.00
214_V237_V2.3311.00
306_A309_M2.3281.00
214_V261_C2.3121.00
489_L492_Y2.2951.00
273_L277_N2.2771.00
456_L463_K2.2701.00
120_S338_A2.2571.00
272_W309_M2.2071.00
17_S102_L2.2001.00
487_S490_K2.1911.00
169_L182_V2.1741.00
315_I318_R2.1081.00
276_L311_L2.0741.00
526_T530_A2.0291.00
284_E319_L2.0221.00
494_R498_I2.0211.00
410_Y422_L2.0171.00
484_T487_S2.0031.00
206_F275_L2.0031.00
280_R319_L2.0011.00
268_L309_M1.9991.00
510_W518_R1.9961.00
217_R220_V1.9881.00
491_I495_D1.9681.00
23_K28_Q1.9601.00
308_Q331_S1.9591.00
89_F94_L1.9441.00
264_Y267_E1.9431.00
481_E485_R1.9401.00
392_V440_D1.9141.00
211_V234_Y1.9041.00
269_E314_R1.9021.00
131_K135_L1.8971.00
406_T425_S1.8821.00
7_A145_V1.8701.00
166_T299_S1.8471.00
169_L180_V1.8441.00
20_A339_A1.8371.00
208_H212_D1.8361.00
523_R527_D1.8191.00
484_T488_A1.8181.00
249_H260_E1.8121.00
20_A335_A1.8061.00
104_E108_E1.8011.00
51_I97_L1.7981.00
514_L517_E1.7671.00
45_M97_L1.7571.00
392_V442_R1.7371.00
97_L100_R1.7351.00
173_L178_F1.7341.00
8_I19_I1.7291.00
7_A342_A1.7291.00
213_E271_L1.7261.00
281_V285_Q1.7151.00
83_R88_T1.7061.00
368_V378_S1.6951.00
167_R184_E1.6821.00
18_L38_L1.6801.00
511_A514_L1.6781.00
101_S105_D1.6691.00
522_G526_T1.6581.00
530_A533_Q1.6561.00
182_V297_I1.6461.00
408_N425_S1.6421.00
270_D273_L1.6341.00
83_R86_S1.6201.00
268_L306_A1.6201.00
367_E408_N1.6171.00
135_L138_E1.6111.00
480_E484_T1.6081.00
210_L237_V1.5981.00
357_T386_T1.5951.00
72_F98_V1.5761.00
272_W276_L1.5721.00
280_R284_E1.5681.00
518_R522_G1.5661.00
515_G519_E1.5631.00
138_E143_N1.5561.00
138_E476_A1.5541.00
299_S325_Y1.5491.00
95_S133_T1.5491.00
67_K85_G1.5491.00
37_Y332_T1.5461.00
378_S393_E1.5321.00
19_I102_L1.5311.00
96_S139_L1.5211.00
213_E267_E1.5151.00
119_I137_A1.5081.00
280_R315_I1.5081.00
92_P135_L1.5051.00
475_S478_Q1.4981.00
524_V527_D1.4891.00
422_L425_S1.4721.00
72_F95_S1.4681.00
236_C240_A1.4681.00
293_K296_Q1.4631.00
209_M212_D1.4571.00
524_V528_F1.4451.00
213_E217_R1.4431.00
478_Q481_E1.4391.00
18_L29_L1.4371.00
43_I94_L1.4261.00
517_E520_E1.4171.00
74_R205_D1.4141.00
30_I109_F1.4131.00
72_F94_L1.3971.00
46_D50_H1.3971.00
102_L105_D1.3951.00
66_D227_E1.3921.00
75_A78_S1.3851.00
209_M272_W1.3831.00
137_A147_L1.3821.00
267_E271_L1.3781.00
15_T175_G1.3771.00
64_H67_K1.3721.00
149_N152_T1.3721.00
490_K494_R1.3711.00
276_L315_I1.3571.00
73_K150_E1.3561.00
281_V284_E1.3561.00
12_L133_T1.3531.00
394_T440_D1.3521.00
214_V233_L1.3501.00
22_W343_A1.3481.00
240_A250_I1.3431.00
211_V237_V1.3431.00
284_E288_R1.3401.00
169_L283_I1.3251.00
485_R488_A1.3221.00
265_E269_E1.3171.00
482_S485_R1.3131.00
287_L294_P1.3111.00
107_E113_P1.2981.00
14_T176_G1.2921.00
285_Q289_D1.2901.00
497_L501_T1.2811.00
416_K419_N1.2791.00
529_D533_Q1.2771.00
12_L99_L1.2751.00
438_S458_E1.2741.00
206_F268_L1.2641.00
17_S41_S1.2631.00
216_K219_D1.2521.00
12_L95_S1.2521.00
516_D520_E1.2491.00
130_R149_N1.2451.00
206_F272_W1.2421.00
367_E375_G1.2411.00
360_C445_Y1.2401.00
126_S129_Q1.2381.00
134_R450_L1.2331.00
180_V286_A1.2331.00
314_R317_V1.2271.00
416_K500_R1.2231.00
491_I494_R1.2211.00
178_F279_L1.2181.00
45_M89_F1.2181.00
167_R292_L1.2181.00
520_E524_V1.2161.00
432_K435_A1.2151.00
151_P179_D1.2091.00
390_S442_R1.2071.00
60_R64_H1.2071.00
212_D224_T1.2051.00
42_I70_A1.1931.00
510_W514_L1.1901.00
523_R526_T1.1901.00
184_E193_H1.1881.00
206_F309_M1.1851.00
217_R261_C1.1851.00
236_C239_A1.1841.00
390_S444_S1.1731.00
213_E263_F1.1691.00
273_L311_L1.1661.00
499_N535_N1.1651.00
29_L336_L1.1641.00
277_N315_I1.1611.00
248_L252_W1.1581.00
511_A515_G1.1581.00
519_E522_G1.1561.00
385_T389_V1.1561.00
404_S427_D1.1531.00
492_Y495_D1.1521.00
377_F410_Y1.1501.00
316_A324_P1.1471.00
285_Q288_R1.1411.00
240_A248_L1.1411.00
72_F82_W1.1331.00
103_K142_L1.1251.00
400_P433_T1.1241.00
76_M133_T1.1221.00
249_H262_E1.1201.00
33_K105_D1.1201.00
196_A285_Q1.1121.00
167_R193_H1.1111.00
286_A290_A1.1061.00
208_H234_Y1.1031.00
216_K224_T1.1011.00
31_P37_Y1.0991.00
503_K532_L1.0961.00
289_D383_R1.0961.00
248_L253_Q1.0951.00
531_A534_S1.0941.00
127_D131_K1.0921.00
379_P415_H1.0921.00
311_L314_R1.0861.00
282_P286_A1.0811.00
167_R298_D1.0811.00
272_W275_L1.0791.00
100_R104_E1.0771.00
69_A94_L1.0761.00
360_C381_I1.0761.00
217_R221_A1.0751.00
69_A72_F1.0681.00
212_D216_K1.0670.99
515_G522_G1.0650.99
44_S60_R1.0610.99
275_L278_R1.0600.99
182_V292_L1.0580.99
457_L460_G1.0570.99
446_D452_E1.0530.99
440_D458_E1.0530.99
219_D222_R1.0490.99
530_A534_S1.0480.99
183_L192_V1.0450.99
501_T505_K1.0430.99
149_N358_D1.0410.99
169_L320_F1.0410.99
166_T298_D1.0360.99
499_N502_F1.0360.99
503_K535_N1.0310.99
240_A263_F1.0310.99
429_P459_D1.0290.99
93_E97_L1.0270.99
511_A516_D1.0260.99
27_A336_L1.0210.99
405_I439_I1.0210.99
93_E139_L1.0190.99
440_D456_L1.0120.99
176_G179_D1.0110.99
283_I319_L1.0100.99
196_A282_P1.0090.99
283_I316_A1.0070.99
89_F97_L1.0050.99
213_E261_C1.0030.99
311_L315_I1.0010.99
510_W516_D1.0010.99
500_R503_K1.0000.99
397_T402_Q0.9990.99
367_E410_Y0.9990.99
208_H211_V0.9950.99
22_W27_A0.9950.99
394_T438_S0.9950.99
495_D498_I0.9940.99
209_M275_L0.9870.99
499_N503_K0.9840.99
78_S81_N0.9820.99
302_L316_A0.9740.99
123_A151_P0.9740.99
474_L482_S0.9700.99
480_E483_R0.9700.99
150_E179_D0.9680.99
506_L510_W0.9670.99
8_I117_V0.9670.99
531_A536_D0.9640.99
121_V147_L0.9630.99
525_I529_D0.9620.99
272_W311_L0.9610.99
509_L513_A0.9610.99
251_R260_E0.9570.99
218_A254_Y0.9540.99
409_V443_F0.9490.99
101_S104_E0.9470.99
412_G420_N0.9460.99
76_M95_S0.9450.99
520_E523_R0.9440.99
206_F276_L0.9440.99
145_V345_R0.9430.99
531_A537_M0.9410.99
182_V290_A0.9410.99
280_R283_I0.9390.99
287_L292_L0.9330.99
217_R259_R0.9320.99
226_N229_E0.9310.99
513_A518_R0.9230.99
92_P132_H0.9230.99
502_F505_K0.9230.99
394_T458_E0.9190.98
104_E107_E0.9160.98
137_A144_A0.9140.98
194_A290_A0.9140.98
232_A236_C0.9130.98
44_S52_L0.9130.98
531_A535_N0.9120.98
317_V324_P0.9060.98
136_A140_A0.9000.98
512_R516_D0.8990.98
277_N280_R0.8990.98
45_M84_L0.8980.98
431_K435_A0.8960.98
206_F306_A0.8950.98
341_Q344_C0.8920.98
498_I501_T0.8900.98
72_F76_M0.8900.98
193_H292_L0.8900.98
222_R225_L0.8780.98
75_A80_T0.8770.98
507_E510_W0.8760.98
285_Q383_R0.8700.98
315_I319_L0.8680.98
410_Y417_V0.8670.98
105_D108_E0.8660.98
215_L233_L0.8650.98
6_L112_R0.8630.98
373_V398_M0.8610.98
125_F129_Q0.8550.98
363_S413_E0.8550.98
527_D531_A0.8550.98
510_W513_A0.8530.98
151_P177_T0.8530.98
508_E512_R0.8520.98
73_K176_G0.8510.98
214_V250_I0.8490.97
486_L489_L0.8490.97
521_I524_V0.8470.97
499_N532_L0.8450.97
31_P109_F0.8420.97
121_V130_R0.8410.97
269_E311_L0.8410.97
11_D14_T0.8410.97
534_S537_M0.8380.97
211_V230_L0.8350.97
478_Q482_S0.8330.97
21_V110_L0.8280.97
284_E294_P0.8240.97
192_V358_D0.8210.97
45_M94_L0.8160.97
300_L320_F0.8150.97
121_V149_N0.8140.97
7_A116_D0.8140.97
510_W522_G0.8130.97
73_K177_T0.8100.97
146_R341_Q0.8090.97
119_I144_A0.8090.97
526_T529_D0.8070.97
364_L443_F0.8070.97
29_L37_Y0.8070.97
191_E386_T0.8050.97
149_N195_S0.7990.96
414_N493_P0.7970.96
99_L133_T0.7930.96
292_L296_Q0.7930.96
485_R489_L0.7920.96
219_D224_T0.7890.96
119_I133_T0.7870.96
515_G518_R0.7870.96
368_V395_Y0.7850.96
173_L279_L0.7840.96
75_A82_W0.7830.96
42_I58_V0.7800.96
186_A189_V0.7790.96
134_R147_L0.7780.96
474_L479_I0.7770.96
431_K457_L0.7760.96
519_E530_A0.7750.96
210_L213_E0.7740.96
123_A179_D0.7740.96
509_L512_R0.7730.96
526_T533_Q0.7710.96
269_E309_M0.7700.96
173_L312_V0.7650.95
510_W515_G0.7650.95
230_L234_Y0.7640.95
196_A286_A0.7640.95
39_T105_D0.7630.95
277_N281_V0.7630.95
506_L511_A0.7620.95
516_D519_E0.7610.95
62_T231_A0.7590.95
325_Y333_I0.7590.95
263_F268_L0.7580.95
533_Q536_D0.7570.95
283_I320_F0.7550.95
32_N105_D0.7550.95
8_I106_A0.7540.95
138_E483_R0.7520.95
397_T400_P0.7520.95
481_E484_T0.7510.95
55_K59_S0.7450.95
32_N35_G0.7420.95
407_V441_I0.7420.95
513_A516_D0.7410.94
9_G335_A0.7400.94
294_P319_L0.7400.94
355_I447_I0.7370.94
171_F178_F0.7370.94
218_A259_R0.7360.94
467_I470_S0.7340.94
488_A492_Y0.7320.94
44_S64_H0.7310.94
513_A517_E0.7300.94
34_F55_K0.7300.94
175_G179_D0.7290.94
249_H253_Q0.7290.94
151_P154_A0.7280.94
214_V263_F0.7280.94
20_A29_L0.7280.94
28_Q31_P0.7260.94
173_L306_A0.7260.94
414_N419_N0.7250.94
265_E310_P0.7240.94
7_A346_L0.7240.94
173_L275_L0.7240.94
123_A176_G0.7200.94
482_S486_L0.7180.94
41_S98_V0.7180.94
58_V238_E0.7160.93
134_R138_E0.7140.93
509_L521_I0.7130.93
444_S452_E0.7120.93
400_P434_G0.7100.93
345_R447_I0.7090.93
512_R517_E0.7070.93
382_E385_T0.7040.93
493_P504_A0.7030.93
298_D322_K0.7030.93
100_R103_K0.7030.93
336_L340_I0.7010.93
44_S68_T0.7000.93
443_F451_L0.6960.92
211_V233_L0.6950.92
117_V142_L0.6950.92
150_E177_T0.6940.92
70_A78_S0.6920.92
383_R413_E0.6910.92
517_E521_I0.6900.92
515_G526_T0.6890.92
466_V469_H0.6890.92
349_E352_E0.6880.92
152_T358_D0.6860.92
519_E527_D0.6850.92
525_I528_F0.6850.92
131_K134_R0.6830.92
196_A199_N0.6780.91
154_A303_V0.6780.91
69_A82_W0.6770.91
17_S98_V0.6770.91
477_Q480_E0.6760.91
223_T226_N0.6760.91
170_V301_V0.6750.91
512_R515_G0.6750.91
496_M499_N0.6750.91
14_T177_T0.6720.91
509_L532_L0.6720.91
520_E527_D0.6720.91
363_S383_R0.6720.91
16_N71_L0.6710.91
133_T151_P0.6710.91
76_M132_H0.6700.91
507_E511_A0.6680.91
51_I100_R0.6670.91
14_T73_K0.6650.91
224_T230_L0.6650.91
171_F280_R0.6650.91
514_L518_R0.6650.91
523_R530_A0.6620.90
181_T204_E0.6600.90
172_D176_G0.6600.90
410_Y425_S0.6600.90
468_N471_P0.6590.90
528_F531_A0.6590.90
214_V259_R0.6590.90
211_V215_L0.6580.90
396_S437_Q0.6560.90
33_K101_S0.6560.90
513_A521_I0.6550.90
526_T532_L0.6550.90
521_I528_F0.6540.90
243_S246_S0.6520.90
164_Q298_D0.6500.90
500_R504_A0.6500.90
64_H68_T0.6500.90
198_D201_L0.6490.90
488_A491_I0.6480.90
343_A351_I0.6470.89
513_A524_V0.6470.89
200_F283_I0.6460.89
477_Q481_E0.6460.89
37_Y329_D0.6450.89
207_T234_Y0.6450.89
511_A519_E0.6450.89
514_L524_V0.6440.89
118_V342_A0.6430.89
359_I384_N0.6430.89
67_K84_L0.6410.89
47_E85_G0.6360.89
282_P287_L0.6340.88
122_P125_F0.6330.88
510_W519_E0.6330.88
215_L230_L0.6310.88
521_I533_Q0.6300.88
533_Q537_M0.6300.88
156_M341_Q0.6300.88
507_E512_R0.6290.88
415_H497_L0.6290.88
149_N449_G0.6270.88
509_L514_L0.6270.88
526_T534_S0.6250.88
496_M501_T0.6250.88
133_T179_D0.6240.88
288_R291_R0.6240.88
303_V333_I0.6230.88
151_P176_G0.6220.88
173_L307_S0.6220.88
477_Q527_D0.6220.88
167_R297_I0.6220.88
428_V434_G0.6190.87
32_N36_E0.6180.87
213_E216_K0.6170.87
532_L535_N0.6170.87
123_A177_T0.6170.87
209_M271_L0.6130.87
508_E514_L0.6120.87
437_Q457_L0.6120.87
527_D530_A0.6110.87
302_L307_S0.6110.87
302_L324_P0.6090.86
499_N520_E0.6090.86
123_A133_T0.6090.86
306_A331_S0.6090.86
528_F532_L0.6080.86
431_K437_Q0.6070.86
442_R454_D0.6070.86
210_L214_V0.6060.86
133_T177_T0.6060.86
532_L537_M0.6050.86
22_W25_G0.6050.86
332_T336_L0.6040.86
508_E515_G0.6040.86
10_I117_V0.6030.86
115_K143_N0.6030.86
215_L223_T0.6010.86
486_L493_P0.6000.86
74_R197_G0.5990.86
21_V109_F0.5980.85
266_N269_E0.5970.85
8_I114_I0.5970.85
218_A257_E0.5970.85
196_A289_D0.5970.85
73_K179_D0.5970.85
495_D499_N0.5970.85
489_L493_P0.5970.85
43_I53_V0.5960.85
92_P96_S0.5960.85
512_R522_G0.5960.85
12_L331_S0.5960.85
529_D535_N0.5950.85
103_K117_V0.5950.85
509_L531_A0.5950.85
496_M537_M0.5940.85
53_V98_V0.5930.85
529_D532_L0.5920.85
530_A537_M0.5910.85
446_D450_L0.5910.85
248_L251_R0.5910.85
133_T150_E0.5900.85
87_D93_E0.5900.85
499_N537_M0.5900.85
360_C364_L0.5900.85
70_A75_A0.5890.85
300_L316_A0.5880.84
189_V357_T0.5880.84
117_V144_A0.5880.84
402_Q434_G0.5870.84
397_T432_K0.5860.84
178_F201_L0.5860.84
27_A30_I0.5840.84
145_V342_A0.5840.84
294_P320_F0.5840.84
15_T335_A0.5830.84
362_Y411_Q0.5830.84
494_R497_L0.5820.84
263_F267_E0.5820.84
249_H252_W0.5820.84
499_N531_A0.5820.84
120_S334_V0.5820.84
506_L513_A0.5800.84
11_D176_G0.5800.84
272_W306_A0.5800.84
513_A528_F0.5800.84
154_A175_G0.5790.84
77_G132_H0.5790.84
32_N37_Y0.5780.83
366_V441_I0.5780.83
375_G418_K0.5780.83
172_D177_T0.5770.83
185_Y190_I0.5770.83
154_A334_V0.5760.83
442_R456_L0.5760.83
203_G306_A0.5750.83
523_R537_M0.5750.83
253_Q256_E0.5730.83
515_G523_R0.5730.83
519_E526_T0.5720.83
99_L142_L0.5720.83
526_T537_M0.5720.83
506_L514_L0.5710.83
482_S489_L0.5710.83
509_L518_R0.5710.83
506_L516_D0.5700.83
497_L502_F0.5700.83
525_I536_D0.5690.83
237_V240_A0.5680.82
269_E272_W0.5680.82
397_T405_I0.5670.82
471_P479_I0.5670.82
246_S265_E0.5670.82
155_A159_G0.5660.82
163_Q325_Y0.5650.82
125_F133_T0.5640.82
207_T238_E0.5640.82
198_D281_V0.5640.82
520_E526_T0.5640.82
124_Y198_D0.5640.82
507_E514_L0.5630.82
242_C265_E0.5630.82
522_G530_A0.5630.82
134_R448_N0.5630.82
428_V437_Q0.5620.82
189_V355_I0.5620.82
396_S438_S0.5610.82
201_L278_R0.5600.82
413_E420_N0.5590.81
66_D85_G0.5580.81
508_E511_A0.5570.81
309_M312_V0.5570.81
397_T434_G0.5570.81
516_D530_A0.5570.81
204_E207_T0.5560.81
194_A289_D0.5560.81
19_I105_D0.5560.81
509_L517_E0.5560.81
524_V532_L0.5540.81
426_F455_V0.5540.81
517_E524_V0.5530.81
364_L412_G0.5530.81
417_V420_N0.5520.81
221_A261_C0.5520.81
487_S491_I0.5520.81
502_F532_L0.5510.80
104_E297_I0.5510.80
519_E537_M0.5510.80
507_E522_G0.5480.80
475_S479_I0.5470.80
483_R486_L0.5450.80
360_C363_S0.5450.80
469_H473_T0.5450.80
522_G529_D0.5440.80
20_A27_A0.5440.80
184_E191_E0.5430.80
527_D537_M0.5420.79
525_I535_N0.5420.79
470_S473_T0.5420.79
508_E520_E0.5410.79
522_G525_I0.5410.79
135_L474_L0.5410.79
16_N38_L0.5400.79
46_D52_L0.5390.79
135_L139_L0.5390.79
499_N534_S0.5380.79
518_R521_I0.5380.79
268_L272_W0.5380.79
7_A343_A0.5360.79
344_C349_E0.5360.79
95_S99_L0.5360.79
110_L114_I0.5360.79
76_M92_P0.5360.79
18_L335_A0.5360.79
518_R535_N0.5350.79
498_I537_M0.5350.79
504_A509_L0.5350.79
508_E535_N0.5350.79
168_S299_S0.5340.78
250_I261_C0.5340.78
486_L490_K0.5330.78
11_D172_D0.5330.78
10_I13_G0.5320.78
252_W258_T0.5320.78
366_V407_V0.5320.78
500_R535_N0.5320.78
368_V393_E0.5310.78
210_L250_I0.5310.78
428_V431_K0.5310.78
9_G13_G0.5310.78
255_Q258_T0.5300.78
226_N255_Q0.5290.78
15_T179_D0.5280.78
503_K509_L0.5280.78
468_N473_T0.5270.77
241_K306_A0.5260.77
103_K140_A0.5250.77
17_S177_T0.5250.77
191_E357_T0.5240.77
516_D535_N0.5230.77
522_G528_F0.5220.77
492_Y524_V0.5220.77
232_A251_R0.5220.77
201_L205_D0.5210.77
507_E519_E0.5210.77
252_W256_E0.5210.77
520_E535_N0.5210.77
496_M500_R0.5210.77
477_Q511_A0.5210.77
60_R68_T0.5200.77
368_V376_I0.5190.76
91_A95_S0.5190.76
521_I530_A0.5190.76
157_A333_I0.5180.76
511_A522_G0.5180.76
158_Y333_I0.5180.76
41_S73_K0.5170.76
215_L218_A0.5170.76
50_H496_M0.5170.76
69_A84_L0.5160.76
510_W527_D0.5150.76
302_L326_Q0.5150.76
107_E114_I0.5150.76
177_T205_D0.5150.76
488_A520_E0.5150.76
60_R63_S0.5130.76
381_I445_Y0.5130.76
223_T229_E0.5130.76
167_R296_Q0.5120.75
509_L516_D0.5120.75
491_I520_E0.5120.75
474_L478_Q0.5110.75
466_V470_S0.5110.75
250_I253_Q0.5110.75
154_A177_T0.5110.75
492_Y511_A0.5090.75
514_L522_G0.5080.75
253_Q258_T0.5070.75
499_N517_E0.5050.74
53_V97_L0.5050.74
279_L312_V0.5040.74
514_L528_F0.5030.74
502_F537_M0.5030.74
501_T512_R0.5020.74
505_K509_L0.5020.74
486_L497_L0.5020.74
9_G339_A0.5020.74
229_E236_C0.5020.74
89_F93_E0.5010.74
178_F282_P0.5010.74
366_V443_F0.5000.74
530_A535_N0.5000.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d2fA 1 0.9856 100 0.154 Contact Map
4jneA 2 0.9694 100 0.156 Contact Map
4fl9A 1 0.8957 100 0.191 Contact Map
2v7yA 1 0.8813 100 0.205 Contact Map
4rtfD 1 0.6097 100 0.222 Contact Map
3i33A 1 0.6115 100 0.44 Contact Map
4kboA 1 0.6133 100 0.441 Contact Map
4j8fA 2 0.8921 100 0.455 Contact Map
4gniA 2 0.6115 100 0.48 Contact Map
3qfuA 1 0.6151 100 0.51 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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