YDEN - ECOLI - GREMLIN Contacts

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YDEN - Uncharacterized sulfatase YdeN

UniProt:	P77318	Sequences: MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAFSDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAIEAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGIPLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQNRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPFMLYLAYNAPHLPNDNPAPDQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQYDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKLISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEENIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTDLQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13796
Length:	560 (435)
Sequences:	2374 (1818)
Seq/√Len:	87.1

ECOLI - YDEN ASLA YIDJ
HALSA - Q9HSV3 Q9HQ44 Q9HQQ2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
404_D	420_S	7.193	1.00
330_K	335_Y	4.950	1.00
458_Y	505_K	4.374	1.00
327_E	331_K	4.229	1.00
267_D	328_Q	4.048	1.00
111_T	323_K	3.967	1.00
259_T	282_Y	3.780	1.00
118_E	379_W	3.577	1.00
263_I	328_Q	3.480	1.00
326_L	340_I	3.404	1.00
65_M	68_L	3.363	1.00
74_P	113_L	3.282	1.00
522_V	525_E	3.228	1.00
262_A	278_L	3.011	1.00
460_K	511_Q	2.924	1.00
60_I	171_F	2.891	1.00
280_L	325_I	2.837	1.00
282_Y	321_G	2.833	1.00
63_L	322_V	2.718	1.00
260_D	324_R	2.717	1.00
339_I	378_M	2.716	1.00
328_Q	332_N	2.663	1.00
174_H	408_I	2.648	1.00
65_M	342_F	2.537	1.00
400_P	418_G	2.534	1.00
147_R	417_D	2.504	1.00
348_A	357_N	2.500	1.00
61_I	340_I	2.497	1.00
243_K	261_E	2.460	1.00
60_I	406_A	2.442	1.00
180_A	279_Y	2.401	1.00
295_D	299_K	2.389	1.00
115_L	377_F	2.388	1.00
259_T	321_G	2.374	1.00
341_L	402_A	2.329	1.00
456_D	525_E	2.323	1.00
125_G	393_I	2.321	1.00
179_A	265_V	2.286	1.00
135_S	395_A	2.283	1.00
114_S	118_E	2.252	1.00
436_N	529_V	2.210	1.00
181_V	278_L	2.210	1.00
263_I	324_R	2.200	1.00
114_S	330_K	2.186	1.00
335_Y	379_W	2.179	1.00
266_V	325_I	2.160	1.00
68_L	342_F	2.104	1.00
393_I	421_L	2.093	1.00
124_N	455_W	2.077	1.00
405_A	422_L	2.061	1.00
403_L	408_I	1.983	1.00
261_E	264_G	1.978	1.00
398_F	402_A	1.967	1.00
65_M	318_V	1.954	1.00
120_V	388_N	1.945	1.00
167_L	277_M	1.936	1.00
502_G	514_N	1.931	1.00
516_A	523_V	1.927	1.00
297_Y	320_Q	1.905	1.00
264_G	268_R	1.902	1.00
330_K	379_W	1.859	1.00
112_L	342_F	1.852	1.00
335_Y	340_I	1.849	1.00
143_R	164_E	1.816	1.00
339_I	405_A	1.800	1.00
75_F	121_R	1.787	1.00
404_D	422_L	1.763	1.00
267_D	331_K	1.762	1.00
299_K	302_N	1.734	1.00
267_D	332_N	1.732	1.00
328_Q	331_K	1.718	1.00
301_F	316_Y	1.713	1.00
64_T	139_I	1.705	1.00
62_V	341_L	1.674	1.00
456_D	529_V	1.673	1.00
64_T	343_T	1.631	1.00
170_L	403_L	1.629	1.00
259_T	263_I	1.590	1.00
60_I	405_A	1.561	1.00
295_D	298_Q	1.559	1.00
177_Y	269_A	1.539	1.00
128_A	145_P	1.519	1.00
255_S	284_A	1.499	1.00
461_F	523_V	1.495	1.00
59_N	338_T	1.494	1.00
177_Y	274_Q	1.494	1.00
256_D	317_S	1.487	0.99
115_L	379_W	1.486	0.99
259_T	325_I	1.484	0.99
344_S	374_T	1.480	0.99
133_G	150_V	1.476	0.99
111_T	114_S	1.474	0.99
68_L	315_V	1.467	0.99
61_I	329_L	1.456	0.99
326_L	335_Y	1.451	0.99
329_L	335_Y	1.448	0.99
120_V	384_L	1.433	0.99
68_L	285_P	1.430	0.99
180_A	281_A	1.416	0.99
119_G	377_F	1.415	0.99
160_I	166_F	1.413	0.99
515_L	519_N	1.410	0.99
341_L	378_M	1.408	0.99
172_Q	201_R	1.400	0.99
126_Y	372_T	1.399	0.99
519_N	522_V	1.379	0.99
368_Y	502_G	1.363	0.99
114_S	327_E	1.350	0.99
121_R	389_Y	1.341	0.99
170_L	399_Y	1.324	0.99
64_T	281_A	1.321	0.99
123_T	390_D	1.318	0.99
291_N	313_A	1.314	0.99
454_F	526_M	1.313	0.99
455_W	458_Y	1.310	0.99
282_Y	318_V	1.307	0.99
383_K	426_Q	1.294	0.99
57_K	174_H	1.291	0.99
63_L	340_I	1.290	0.99
256_D	321_G	1.275	0.98
340_I	379_W	1.265	0.98
285_P	315_V	1.259	0.98
62_V	343_T	1.249	0.98
254_I	258_L	1.248	0.98
339_I	380_W	1.241	0.98
138_A	145_P	1.238	0.98
125_G	376_M	1.236	0.98
146_A	440_I	1.232	0.98
255_S	282_Y	1.231	0.98
454_F	461_F	1.230	0.98
258_L	280_L	1.229	0.98
76_D	377_F	1.226	0.98
108_S	301_F	1.226	0.98
459_H	515_L	1.223	0.98
59_N	276_F	1.220	0.98
515_L	522_V	1.216	0.98
270_K	332_N	1.216	0.98
372_T	439_W	1.215	0.98
171_F	402_A	1.212	0.98
194_V	197_D	1.206	0.98
67_D	364_K	1.205	0.98
122_F	376_M	1.203	0.98
253_Y	317_S	1.201	0.98
241_L	244_N	1.201	0.98
324_R	327_E	1.200	0.98
76_D	121_R	1.197	0.98
300_Q	316_Y	1.195	0.98
458_Y	522_V	1.185	0.97
116_M	121_R	1.180	0.97
350_I	363_Y	1.178	0.97
422_L	426_Q	1.170	0.97
68_L	73_L	1.169	0.97
179_A	278_L	1.167	0.97
165_T	173_N	1.164	0.97
378_M	384_L	1.163	0.97
327_E	330_K	1.160	0.97
118_E	335_Y	1.158	0.97
114_S	326_L	1.152	0.97
263_I	267_D	1.147	0.97
380_W	383_K	1.141	0.97
262_A	280_L	1.139	0.97
127_V	374_T	1.136	0.97
195_P	199_Q	1.131	0.97
124_N	373_H	1.124	0.96
404_D	423_P	1.117	0.96
61_I	278_L	1.103	0.96
378_M	421_L	1.101	0.96
132_S	136_R	1.100	0.96
109_T	113_L	1.098	0.96
359_A	509_L	1.093	0.96
513_D	518_A	1.092	0.96
265_V	269_A	1.088	0.96
108_S	316_Y	1.086	0.96
58_P	176_Y	1.085	0.96
296_Q	300_Q	1.072	0.95
304_G	309_D	1.072	0.95
213_E	216_Q	1.070	0.95
130_G	367_T	1.068	0.95
253_Y	314_S	1.058	0.95
339_I	402_A	1.055	0.95
112_L	115_L	1.052	0.95
515_L	518_A	1.050	0.95
179_A	202_D	1.046	0.95
61_I	338_T	1.041	0.95
60_I	402_A	1.039	0.95
140_M	279_Y	1.036	0.94
262_A	266_V	1.035	0.94
320_Q	324_R	1.034	0.94
438_T	454_F	1.033	0.94
243_K	246_E	1.033	0.94
140_M	186_L	1.019	0.94
364_K	371_G	1.017	0.94
115_L	326_L	1.015	0.94
67_D	371_G	1.015	0.94
244_N	247_R	1.014	0.94
56_G	337_N	1.014	0.94
305_S	309_D	1.014	0.94
133_G	185_H	1.011	0.94
165_T	170_L	1.011	0.94
109_T	112_L	1.010	0.94
361_K	368_Y	1.008	0.94
440_I	443_Y	1.003	0.93
376_M	398_F	1.000	0.93
118_E	330_K	0.997	0.93
487_N	490_Y	0.989	0.93
167_L	171_F	0.971	0.92
61_I	276_F	0.969	0.92
317_S	321_G	0.965	0.92
67_D	346_N	0.962	0.92
62_V	277_M	0.960	0.92
459_H	519_N	0.958	0.92
127_V	135_S	0.956	0.92
195_P	200_T	0.955	0.92
184_W	187_S	0.953	0.92
73_L	76_D	0.950	0.91
309_D	312_Y	0.947	0.91
399_Y	403_L	0.946	0.91
313_A	317_S	0.945	0.91
284_A	318_V	0.942	0.91
122_F	424_W	0.940	0.91
411_P	414_L	0.939	0.91
70_Y	346_N	0.939	0.91
298_Q	313_A	0.933	0.91
427_D	430_Q	0.933	0.91
167_L	399_Y	0.933	0.91
529_V	532_E	0.933	0.91
267_D	327_E	0.932	0.91
61_I	326_L	0.931	0.91
460_K	506_L	0.930	0.91
69_G	371_G	0.929	0.91
266_V	269_A	0.927	0.90
221_G	226_M	0.924	0.90
276_F	338_T	0.923	0.90
459_H	503_L	0.923	0.90
75_F	113_L	0.922	0.90
143_R	148_F	0.922	0.90
329_L	332_N	0.917	0.90
296_Q	320_Q	0.913	0.90
69_G	346_N	0.912	0.90
64_T	395_A	0.905	0.89
524_K	527_Q	0.904	0.89
500_Q	514_N	0.903	0.89
115_L	119_G	0.903	0.89
326_L	379_W	0.903	0.89
529_V	533_F	0.899	0.89
167_L	402_A	0.899	0.89
120_V	386_P	0.898	0.89
67_D	348_A	0.895	0.89
171_F	339_I	0.892	0.89
505_K	522_V	0.889	0.89
321_G	324_R	0.887	0.88
69_G	72_Q	0.886	0.88
420_S	423_P	0.885	0.88
459_H	522_V	0.884	0.88
138_A	396_M	0.884	0.88
70_Y	123_T	0.881	0.88
300_Q	313_A	0.880	0.88
65_M	285_P	0.880	0.88
69_G	348_A	0.878	0.88
436_N	456_D	0.877	0.88
276_F	334_Q	0.875	0.88
61_I	325_I	0.873	0.88
270_K	334_Q	0.872	0.88
523_V	527_Q	0.870	0.87
128_A	138_A	0.870	0.87
348_A	356_L	0.867	0.87
241_L	245_R	0.866	0.87
291_N	314_S	0.858	0.87
238_S	242_F	0.856	0.87
255_S	321_G	0.851	0.86
239_P	244_N	0.850	0.86
299_K	303_T	0.849	0.86
115_L	322_V	0.848	0.86
258_L	283_N	0.847	0.86
484_T	487_N	0.846	0.86
171_F	408_I	0.845	0.86
269_A	274_Q	0.845	0.86
122_F	378_M	0.844	0.86
122_F	425_L	0.843	0.86
461_F	526_M	0.842	0.86
309_D	313_A	0.838	0.85
329_L	340_I	0.835	0.85
392_L	434_H	0.835	0.85
114_S	335_Y	0.832	0.85
74_P	109_T	0.830	0.85
141_T	164_E	0.830	0.85
112_L	377_F	0.829	0.85
344_S	375_P	0.828	0.85
208_T	211_S	0.822	0.84
69_G	370_G	0.819	0.84
528_G	532_E	0.819	0.84
221_G	224_Y	0.817	0.84
203_Y	206_N	0.816	0.84
369_P	460_K	0.814	0.84
369_P	455_W	0.814	0.84
76_D	376_M	0.813	0.84
200_T	205_D	0.812	0.84
291_N	298_Q	0.810	0.83
306_Q	309_D	0.810	0.83
243_K	247_R	0.808	0.83
237_N	243_K	0.808	0.83
62_V	402_A	0.807	0.83
325_I	328_Q	0.805	0.83
285_P	311_Y	0.804	0.83
501_L	516_A	0.803	0.83
137_A	150_V	0.802	0.83
144_A	396_M	0.802	0.83
503_L	526_M	0.801	0.83
169_E	172_Q	0.797	0.82
270_K	273_D	0.794	0.82
70_Y	76_D	0.794	0.82
191_N	197_D	0.793	0.82
263_I	325_I	0.793	0.82
59_N	334_Q	0.791	0.82
259_T	324_R	0.790	0.82
290_D	314_S	0.790	0.82
108_S	300_Q	0.782	0.81
485_V	489_D	0.781	0.81
181_V	202_D	0.779	0.81
269_A	272_L	0.779	0.81
439_W	453_P	0.778	0.81
240_S	243_K	0.777	0.81
172_Q	178_T	0.776	0.81
333_G	336_D	0.776	0.81
403_L	410_I	0.773	0.80
169_E	198_K	0.772	0.80
219_N	222_F	0.771	0.80
296_Q	299_K	0.771	0.80
391_K	424_W	0.770	0.80
62_V	139_I	0.767	0.80
228_F	231_A	0.767	0.80
483_Y	486_R	0.765	0.80
260_D	263_I	0.761	0.79
419_V	434_H	0.759	0.79
221_G	225_F	0.758	0.79
524_K	528_G	0.758	0.79
369_P	373_H	0.757	0.79
243_K	248_V	0.757	0.79
63_L	280_L	0.753	0.79
486_R	489_D	0.753	0.79
177_Y	265_V	0.753	0.79
195_P	205_D	0.753	0.79
300_Q	320_Q	0.752	0.79
457_N	505_K	0.749	0.78
126_Y	369_P	0.749	0.78
456_D	522_V	0.748	0.78
438_T	444_S	0.748	0.78
132_S	183_K	0.747	0.78
73_L	121_R	0.745	0.78
200_T	222_F	0.745	0.78
252_G	260_D	0.745	0.78
400_P	416_L	0.741	0.78
127_V	395_A	0.740	0.78
317_S	320_Q	0.740	0.78
136_R	183_K	0.740	0.78
181_V	280_L	0.739	0.77
61_I	266_V	0.738	0.77
507_T	521_Q	0.738	0.77
337_N	526_M	0.737	0.77
103_E	113_L	0.737	0.77
291_N	310_N	0.734	0.77
402_A	406_A	0.732	0.77
125_G	395_A	0.730	0.77
128_A	395_A	0.727	0.76
343_T	395_A	0.725	0.76
483_Y	488_N	0.725	0.76
106_Q	308_A	0.725	0.76
419_V	424_W	0.724	0.76
346_N	371_G	0.724	0.76
396_M	416_L	0.723	0.76
165_T	414_L	0.723	0.76
195_P	198_K	0.722	0.76
253_Y	256_D	0.715	0.75
257_Q	261_E	0.711	0.75
533_F	536_S	0.710	0.75
369_P	506_L	0.709	0.74
72_Q	356_L	0.709	0.74
266_V	332_N	0.708	0.74
378_M	425_L	0.706	0.74
76_D	122_F	0.706	0.74
57_K	175_G	0.706	0.74
419_V	433_P	0.704	0.74
501_L	523_V	0.704	0.74
530_V	534_I	0.701	0.74
147_R	536_S	0.701	0.74
454_F	529_V	0.701	0.74
255_S	280_L	0.697	0.73
435_K	456_D	0.696	0.73
503_L	520_P	0.696	0.73
362_G	366_Q	0.695	0.73
441_T	444_S	0.695	0.73
514_N	517_A	0.693	0.73
61_I	334_Q	0.692	0.73
183_K	364_K	0.691	0.73
385_Q	388_N	0.691	0.73
139_I	398_F	0.688	0.72
520_P	523_V	0.687	0.72
285_P	344_S	0.687	0.72
264_G	267_D	0.686	0.72
265_V	511_Q	0.685	0.72
68_L	318_V	0.684	0.72
238_S	244_N	0.683	0.72
297_Y	300_Q	0.683	0.72
206_N	211_S	0.682	0.72
392_L	437_L	0.682	0.72
136_R	182_G	0.679	0.71
168_P	172_Q	0.679	0.71
133_G	305_S	0.678	0.71
187_S	195_P	0.678	0.71
461_F	501_L	0.676	0.71
241_L	249_P	0.675	0.71
72_Q	371_G	0.675	0.71
209_T	212_A	0.674	0.71
503_L	514_N	0.672	0.70
501_L	527_Q	0.671	0.70
518_A	521_Q	0.671	0.70
202_D	268_R	0.669	0.70
181_V	266_V	0.666	0.70
394_S	437_L	0.665	0.70
226_M	231_A	0.665	0.70
203_Y	207_F	0.664	0.70
67_D	183_K	0.664	0.70
174_H	406_A	0.663	0.69
150_V	154_T	0.662	0.69
490_Y	494_Y	0.656	0.69
484_T	488_N	0.652	0.68
180_A	203_Y	0.652	0.68
318_V	342_F	0.651	0.68
182_G	185_H	0.649	0.68
195_P	204_H	0.649	0.68
237_N	240_S	0.649	0.68
520_P	524_K	0.648	0.68
141_T	166_F	0.646	0.67
120_V	387_G	0.646	0.67
115_L	340_I	0.645	0.67
333_G	454_F	0.642	0.67
240_S	247_R	0.641	0.67
133_G	153_N	0.640	0.67
62_V	398_F	0.639	0.67
238_S	247_R	0.639	0.67
380_W	405_A	0.637	0.66
301_F	405_A	0.637	0.66
463_R	527_Q	0.634	0.66
68_L	112_L	0.632	0.66
217_P	222_F	0.632	0.66
113_L	311_Y	0.630	0.66
255_S	317_S	0.630	0.66
220_R	223_D	0.627	0.65
120_V	385_Q	0.626	0.65
107_K	312_Y	0.626	0.65
522_V	526_M	0.626	0.65
114_S	379_W	0.625	0.65
348_A	370_G	0.624	0.65
364_K	417_D	0.623	0.65
196_E	205_D	0.622	0.65
138_A	148_F	0.622	0.65
383_K	386_P	0.622	0.65
528_G	531_R	0.621	0.64
434_H	438_T	0.621	0.64
72_Q	184_W	0.620	0.64
168_P	178_T	0.620	0.64
298_Q	310_N	0.619	0.64
456_D	459_H	0.619	0.64
164_E	416_L	0.619	0.64
200_T	204_H	0.619	0.64
461_F	527_Q	0.617	0.64
326_L	330_K	0.617	0.64
199_Q	222_F	0.617	0.64
74_P	116_M	0.616	0.64
532_E	535_D	0.615	0.64
187_S	199_Q	0.615	0.64
259_T	280_L	0.615	0.64
121_R	388_N	0.613	0.63
360_Q	509_L	0.613	0.63
72_Q	348_A	0.612	0.63
391_K	430_Q	0.610	0.63
241_L	248_V	0.609	0.63
483_Y	487_N	0.608	0.63
340_I	377_F	0.608	0.63
239_P	243_K	0.606	0.63
58_P	339_I	0.606	0.63
327_E	524_K	0.605	0.62
139_I	395_A	0.605	0.62
484_T	489_D	0.604	0.62
503_L	523_V	0.604	0.62
322_V	342_F	0.603	0.62
125_G	343_T	0.603	0.62
255_S	259_T	0.601	0.62
177_Y	332_N	0.600	0.62
225_F	245_R	0.600	0.62
222_F	226_M	0.598	0.61
485_V	490_Y	0.597	0.61
227_G	231_A	0.596	0.61
107_K	285_P	0.596	0.61
110_P	319_D	0.593	0.61
224_Y	232_G	0.591	0.61
364_K	370_G	0.591	0.61
211_S	216_Q	0.591	0.61
68_L	311_Y	0.589	0.60
384_L	388_N	0.589	0.60
413_D	505_K	0.586	0.60
67_D	136_R	0.585	0.60
378_M	402_A	0.582	0.59
245_R	248_V	0.581	0.59
439_W	506_L	0.579	0.59
239_P	247_R	0.578	0.59
259_T	318_V	0.578	0.59
438_T	533_F	0.577	0.59
135_S	151_Y	0.576	0.59
346_N	370_G	0.576	0.59
171_F	406_A	0.574	0.58
311_Y	315_V	0.574	0.58
376_M	393_I	0.574	0.58
265_V	276_F	0.572	0.58
318_V	322_V	0.571	0.58
426_Q	524_K	0.570	0.58
217_P	225_F	0.569	0.58
69_G	361_K	0.567	0.57
323_K	327_E	0.566	0.57
113_L	117_D	0.565	0.57
63_L	282_Y	0.564	0.57
391_K	432_E	0.564	0.57
527_Q	531_R	0.563	0.57
424_W	433_P	0.563	0.57
147_R	164_E	0.563	0.57
242_F	247_R	0.562	0.57
423_P	428_K	0.561	0.57
440_I	530_V	0.561	0.57
322_V	325_I	0.560	0.57
399_Y	416_L	0.559	0.56
329_L	337_N	0.559	0.56
137_A	148_F	0.559	0.56
206_N	258_L	0.559	0.56
133_G	184_W	0.557	0.56
260_D	264_G	0.557	0.56
423_P	427_D	0.555	0.56
309_D	317_S	0.555	0.56
132_S	182_G	0.554	0.56
199_Q	205_D	0.554	0.56
148_F	151_Y	0.553	0.56
411_P	415_K	0.553	0.56
341_L	398_F	0.552	0.55
146_A	438_T	0.552	0.55
253_Y	290_D	0.552	0.55
284_A	346_N	0.552	0.55
531_R	535_D	0.550	0.55
114_S	260_D	0.548	0.55
370_G	417_D	0.548	0.55
292_P	317_S	0.547	0.55
517_A	520_P	0.546	0.55
204_H	207_F	0.546	0.55
438_T	441_T	0.545	0.55
181_V	258_L	0.543	0.54
458_Y	461_F	0.543	0.54
222_F	227_G	0.542	0.54
164_E	414_L	0.542	0.54
133_G	146_A	0.541	0.54
266_V	329_L	0.540	0.54
120_V	425_L	0.540	0.54
253_Y	257_Q	0.539	0.54
128_A	135_S	0.539	0.54
305_S	316_Y	0.539	0.54
125_G	288_P	0.539	0.54
330_K	340_I	0.538	0.54
56_G	60_I	0.537	0.53
226_M	229_H	0.537	0.53
196_E	202_D	0.536	0.53
56_G	117_D	0.536	0.53
178_T	201_R	0.535	0.53
519_N	523_V	0.534	0.53
238_S	241_L	0.534	0.53
165_T	413_D	0.534	0.53
181_V	262_A	0.533	0.53
296_Q	303_T	0.533	0.53
259_T	262_A	0.533	0.53
139_I	402_A	0.533	0.53
297_Y	302_N	0.531	0.53
60_I	531_R	0.531	0.53
73_L	113_L	0.530	0.52
390_D	507_T	0.530	0.52
65_M	112_L	0.529	0.52
131_V	365_S	0.529	0.52
135_S	355_P	0.528	0.52
502_G	516_A	0.528	0.52
217_P	226_M	0.528	0.52
387_G	407_D	0.528	0.52
75_F	116_M	0.528	0.52
56_G	273_D	0.528	0.52
184_W	279_Y	0.527	0.52
68_L	344_S	0.526	0.52
316_Y	320_Q	0.526	0.52
224_Y	243_K	0.526	0.52
181_V	265_V	0.526	0.52
64_T	154_T	0.525	0.52
107_K	315_V	0.525	0.52
314_S	348_A	0.524	0.52
385_Q	426_Q	0.523	0.52
128_A	394_S	0.523	0.52
242_F	245_R	0.522	0.51
331_K	334_Q	0.522	0.51
151_Y	440_I	0.522	0.51
439_W	445_H	0.522	0.51
297_Y	313_A	0.522	0.51
368_Y	464_H	0.521	0.51
267_D	330_K	0.520	0.51
171_F	403_L	0.520	0.51
236_Y	239_P	0.519	0.51
298_Q	302_N	0.518	0.51
126_Y	145_P	0.518	0.51
140_M	166_F	0.518	0.51
453_P	460_K	0.516	0.51
263_I	340_I	0.516	0.51
521_Q	524_K	0.515	0.50
182_G	364_K	0.512	0.50
56_G	271_T	0.512	0.50
185_H	209_T	0.512	0.50
433_P	436_N	0.512	0.50
276_F	329_L	0.512	0.50
380_W	417_D	0.511	0.50
297_Y	317_S	0.511	0.50
384_L	426_Q	0.510	0.50
75_F	112_L	0.510	0.50
143_R	161_P	0.509	0.50
439_W	443_Y	0.509	0.50
137_A	160_I	0.509	0.50
137_A	149_G	0.509	0.50
396_M	434_H	0.509	0.50
330_K	384_L	0.509	0.50
341_L	376_M	0.509	0.50
252_G	257_Q	0.509	0.50
159_G	164_E	0.508	0.50
331_K	532_E	0.508	0.50
376_M	424_W	0.508	0.50
295_D	429_K	0.507	0.49
322_V	421_L	0.507	0.49
225_F	230_A	0.506	0.49
74_P	390_D	0.506	0.49
526_M	530_V	0.505	0.49
125_G	344_S	0.505	0.49
489_D	494_Y	0.505	0.49
273_D	532_E	0.505	0.49
65_M	322_V	0.504	0.49
140_M	200_T	0.502	0.49
458_Y	507_T	0.502	0.49
120_V	382_G	0.502	0.49
143_R	413_D	0.502	0.49
258_L	284_A	0.501	0.49
113_L	116_M	0.501	0.49
129_H	145_P	0.501	0.49
310_N	314_S	0.501	0.49
434_H	437_L	0.501	0.49
256_D	292_P	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4upiA	2	0.7679	100	0.358	Contact Map
1hdhA	1	0.7375	100	0.358	Contact Map
1p49A	3	0.8071	100	0.359	Contact Map
4uplA	2	0.7696	100	0.362	Contact Map
2vqrA	3	0.7536	100	0.362	Contact Map
4uphA	2	0.7607	100	0.369	Contact Map
1fsuA	1	0.8054	100	0.369	Contact Map
3ed4A	3	0.7804	100	0.373	Contact Map
4upkA	3	0.7607	100	0.376	Contact Map
1aukA	3	0.8036	100	0.378	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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