DTPA - ECOLI - GREMLIN Contacts

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DTPA - Dipeptide and tripeptide permease A

UniProt:	P77304	Sequences: MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINYRNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSPILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDPLMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13939
Length:	500 (460)
Sequences:	4695 (2933)
Seq/√Len:	136.8

ECOLI - DTPA DTPB DTPD YJDL
BACSU - YCLF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
173_L	185_L	4.115	1.00
374_A	378_G	3.975	1.00
288_F	395_G	3.434	1.00
366_I	391_L	3.387	1.00
321_Y	382_V	3.359	1.00
80_L	85_L	3.258	1.00
56_E	305_R	3.195	1.00
85_L	90_V	3.071	1.00
355_I	398_M	2.991	1.00
368_P	462_L	2.952	1.00
298_S	303_A	2.925	1.00
309_H	315_A	2.917	1.00
328_W	390_G	2.871	1.00
466_V	470_V	2.843	1.00
300_N	303_A	2.839	1.00
100_I	121_A	2.710	1.00
403_G	423_W	2.605	1.00
80_L	84_V	2.593	1.00
104_L	121_A	2.581	1.00
104_L	118_G	2.544	1.00
85_L	93_L	2.541	1.00
174_A	319_E	2.535	1.00
99_A	191_L	2.471	1.00
36_G	102_Y	2.456	1.00
310_S	315_A	2.402	1.00
358_V	472_A	2.389	1.00
46_V	300_N	2.362	1.00
94_G	128_L	2.358	1.00
365_L	465_G	2.349	1.00
386_V	390_G	2.328	1.00
303_A	385_L	2.306	1.00
96_I	100_I	2.244	1.00
359_M	394_I	2.221	1.00
374_A	377_A	2.213	1.00
260_F	263_E	2.185	1.00
33_E	130_K	2.162	1.00
30_E	34_R	2.148	1.00
298_S	302_F	2.120	1.00
335_I	339_I	2.103	1.00
348_P	351_T	2.075	1.00
92_M	198_A	2.054	1.00
205_K	208_G	2.048	1.00
105_V	118_G	2.035	1.00
152_F	408_A	2.024	1.00
30_E	33_E	1.986	1.00
361_S	469_A	1.983	1.00
289_F	400_S	1.976	1.00
473_V	477_L	1.975	1.00
366_I	387_A	1.971	1.00
324_L	386_V	1.970	1.00
175_A	318_P	1.961	1.00
340_Y	344_G	1.936	1.00
106_A	187_V	1.935	1.00
37_Y	67_S	1.886	1.00
88_K	201_Q	1.864	1.00
45_A	49_V	1.856	1.00
101_G	122_I	1.852	1.00
469_A	473_V	1.843	1.00
375_S	378_G	1.838	1.00
332_G	394_I	1.835	1.00
208_G	211_P	1.810	1.00
73_L	76_I	1.798	1.00
270_A	273_R	1.797	1.00
241_N	249_L	1.782	1.00
260_F	264_A	1.779	1.00
325_N	393_S	1.772	1.00
372_K	378_G	1.754	1.00
137_L	151_A	1.750	1.00
474_L	478_T	1.726	1.00
98_L	129_F	1.709	1.00
249_L	252_V	1.708	1.00
74_V	81_G	1.701	1.00
373_F	376_D	1.665	1.00
30_E	130_K	1.661	1.00
157_M	330_I	1.652	1.00
373_F	378_G	1.652	1.00
325_N	329_I	1.631	1.00
281_L	294_Q	1.626	1.00
54_M	62_L	1.623	1.00
358_V	362_G	1.609	1.00
259_I	263_E	1.602	1.00
50_K	179_W	1.600	1.00
300_N	304_I	1.598	1.00
113_G	117_M	1.592	1.00
456_V	459_R	1.583	1.00
247_M	251_V	1.577	1.00
46_V	318_P	1.576	1.00
209_S	212_D	1.571	1.00
372_K	375_S	1.546	1.00
287_I	471_I	1.545	1.00
164_F	330_I	1.535	1.00
63_F	297_T	1.531	1.00
480_P	483_H	1.520	1.00
331_I	335_I	1.509	1.00
73_L	123_A	1.506	1.00
56_E	301_F	1.502	1.00
290_V	430_A	1.500	1.00
103_A	187_V	1.500	1.00
472_A	476_L	1.492	1.00
155_Y	159_V	1.483	1.00
249_L	253_A	1.479	1.00
317_E	320_Q	1.477	1.00
262_K	265_F	1.474	1.00
372_K	376_D	1.472	1.00
201_Q	206_Q	1.465	1.00
224_T	227_G	1.465	1.00
354_A	472_A	1.452	1.00
299_L	303_A	1.431	1.00
101_G	125_G	1.430	1.00
380_V	384_W	1.429	1.00
363_A	392_Q	1.426	1.00
248_A	251_V	1.418	1.00
362_G	391_L	1.415	1.00
292_Y	295_M	1.400	1.00
134_S	424_F	1.398	1.00
45_A	301_F	1.394	1.00
245_A	248_A	1.389	1.00
93_L	96_I	1.386	1.00
253_A	256_I	1.383	1.00
339_I	343_M	1.381	1.00
367_L	388_S	1.370	1.00
361_S	472_A	1.364	1.00
181_V	184_A	1.359	1.00
118_G	122_I	1.353	1.00
31_L	158_S	1.351	1.00
55_S	58_D	1.347	1.00
477_L	481_K	1.330	1.00
261_G	265_F	1.330	1.00
48_L	63_F	1.325	1.00
178_G	181_V	1.323	1.00
373_F	377_A	1.317	1.00
463_Q	466_V	1.315	1.00
80_L	90_V	1.306	1.00
171_P	319_E	1.306	1.00
87_T	139_T	1.303	1.00
39_G	170_T	1.302	1.00
156_Y	396_E	1.301	1.00
285_A	426_T	1.298	1.00
217_N	220_N	1.297	1.00
390_G	394_I	1.295	1.00
171_P	320_Q	1.290	1.00
270_A	274_K	1.289	1.00
463_Q	467_A	1.286	1.00
354_A	476_L	1.281	1.00
160_N	325_N	1.277	1.00
139_T	408_A	1.272	1.00
417_G	421_G	1.269	1.00
328_W	393_S	1.268	1.00
204_V	211_P	1.266	1.00
245_A	250_G	1.265	1.00
269_G	273_R	1.253	1.00
347_L	355_I	1.252	1.00
48_L	115_V	1.252	1.00
112_A	116_Y	1.250	1.00
245_A	249_L	1.244	1.00
173_L	177_Y	1.231	1.00
272_R	275_M	1.229	1.00
306_N	379_I	1.228	1.00
184_A	188_V	1.221	1.00
54_M	112_A	1.213	1.00
47_Y	108_S	1.212	1.00
31_L	161_I	1.206	1.00
45_A	59_S	1.196	1.00
350_P	479_A	1.189	1.00
342_K	345_D	1.185	1.00
99_A	194_I	1.182	0.99
242_Q	245_A	1.182	0.99
309_H	318_P	1.181	0.99
170_T	173_L	1.172	0.99
108_S	114_I	1.171	0.99
359_M	395_G	1.166	0.99
246_R	252_V	1.165	0.99
241_N	252_V	1.159	0.99
310_S	313_G	1.159	0.99
157_M	333_S	1.157	0.99
61_T	439_G	1.157	0.99
30_E	155_Y	1.156	0.99
156_Y	329_I	1.155	0.99
246_R	249_L	1.154	0.99
204_V	208_G	1.151	0.99
25_L	200_C	1.151	0.99
272_R	278_A	1.147	0.99
381_S	384_W	1.143	0.99
34_R	37_Y	1.143	0.99
250_G	254_F	1.139	0.99
206_Q	209_S	1.138	0.99
220_N	269_G	1.130	0.99
329_I	396_E	1.128	0.99
99_A	103_A	1.126	0.99
258_V	262_K	1.118	0.99
314_L	320_Q	1.118	0.99
159_V	424_F	1.115	0.99
78_G	417_G	1.111	0.99
309_H	317_E	1.108	0.99
149_D	405_A	1.104	0.99
168_I	320_Q	1.102	0.99
252_V	256_I	1.098	0.99
34_R	130_K	1.097	0.99
243_E	249_L	1.095	0.99
169_A	185_L	1.093	0.99
246_R	250_G	1.091	0.99
400_S	404_L	1.089	0.99
283_L	294_Q	1.086	0.99
126_N	129_F	1.085	0.99
272_R	279_F	1.082	0.99
126_N	130_K	1.081	0.99
130_K	424_F	1.080	0.99
248_A	252_V	1.079	0.99
163_S	326_P	1.069	0.99
188_V	192_I	1.068	0.99
353_F	399_I	1.065	0.99
85_L	89_R	1.058	0.99
362_G	366_I	1.057	0.99
276_I	279_F	1.057	0.99
370_G	384_W	1.056	0.99
141_Y	151_A	1.055	0.99
265_F	269_G	1.054	0.99
356_G	399_I	1.053	0.99
234_I	237_W	1.049	0.99
134_S	155_Y	1.048	0.99
462_L	466_V	1.043	0.99
322_Q	326_P	1.041	0.99
101_G	105_V	1.041	0.99
70_V	123_A	1.040	0.99
307_V	385_L	1.040	0.99
77_G	127_G	1.039	0.99
47_Y	115_V	1.037	0.99
33_E	38_Y	1.030	0.99
32_W	189_G	1.019	0.98
98_L	126_N	1.019	0.98
50_K	175_A	1.019	0.98
351_T	479_A	1.018	0.98
195_V	199_F	1.014	0.98
134_S	420_M	1.007	0.98
240_H	244_V	1.006	0.98
480_P	484_R	1.004	0.98
249_L	256_I	1.003	0.98
49_V	301_F	1.003	0.98
159_V	404_L	1.002	0.98
30_E	129_F	1.001	0.98
237_W	241_N	0.997	0.98
232_I	236_T	0.997	0.98
261_G	264_A	0.989	0.98
297_T	303_A	0.987	0.98
137_L	140_C	0.983	0.98
361_S	365_L	0.982	0.98
234_I	238_L	0.980	0.98
461_F	464_I	0.980	0.98
41_Q	63_F	0.978	0.98
257_V	260_F	0.977	0.98
241_N	245_A	0.975	0.98
247_M	253_A	0.974	0.98
289_F	292_Y	0.972	0.98
292_Y	400_S	0.962	0.98
71_Y	130_K	0.959	0.98
303_A	307_V	0.955	0.98
245_A	251_V	0.952	0.98
268_K	272_R	0.950	0.98
205_K	211_P	0.950	0.98
267_M	271_A	0.949	0.98
298_S	304_I	0.949	0.98
212_D	217_N	0.945	0.98
138_S	408_A	0.944	0.98
250_G	253_A	0.940	0.97
49_V	56_E	0.939	0.97
333_S	337_A	0.939	0.97
267_M	272_R	0.936	0.97
224_T	228_V	0.934	0.97
75_A	421_G	0.932	0.97
150_G	337_A	0.929	0.97
258_V	261_G	0.928	0.97
54_M	58_D	0.927	0.97
34_R	38_Y	0.926	0.97
230_A	234_I	0.925	0.97
73_L	127_G	0.918	0.97
34_R	159_V	0.917	0.97
359_M	391_L	0.910	0.97
283_L	286_I	0.908	0.97
70_V	73_L	0.907	0.97
205_K	209_S	0.906	0.97
46_V	50_K	0.905	0.97
41_Q	293_S	0.904	0.97
172_W	177_Y	0.904	0.97
184_A	187_V	0.903	0.97
282_M	286_I	0.902	0.97
272_R	276_I	0.899	0.97
27_F	158_S	0.894	0.97
241_N	250_G	0.893	0.97
292_Y	393_S	0.892	0.97
78_G	421_G	0.889	0.96
244_V	250_G	0.888	0.96
328_W	386_V	0.886	0.96
199_F	202_R	0.886	0.96
440_M	444_P	0.884	0.96
269_G	272_R	0.883	0.96
58_D	61_T	0.881	0.96
110_H	114_I	0.881	0.96
228_V	264_A	0.880	0.96
134_S	404_L	0.879	0.96
69_L	432_L	0.878	0.96
71_Y	424_F	0.877	0.96
459_R	462_L	0.877	0.96
270_A	279_F	0.875	0.96
32_W	133_P	0.873	0.96
61_T	435_G	0.871	0.96
282_M	407_V	0.871	0.96
171_P	174_A	0.866	0.96
222_L	225_I	0.866	0.96
406_M	482_L	0.865	0.96
222_L	226_I	0.865	0.96
295_M	392_Q	0.864	0.96
368_P	371_A	0.864	0.96
231_L	253_A	0.863	0.96
241_N	248_A	0.861	0.96
241_N	246_R	0.859	0.96
156_Y	160_N	0.858	0.96
64_S	434_G	0.857	0.96
307_V	382_V	0.856	0.96
92_M	95_A	0.855	0.96
333_S	401_G	0.854	0.96
62_L	116_Y	0.853	0.95
299_L	388_S	0.844	0.95
299_L	304_I	0.843	0.95
273_R	487_Q	0.842	0.95
316_V	320_Q	0.841	0.95
396_E	400_S	0.838	0.95
247_M	250_G	0.835	0.95
251_V	255_G	0.835	0.95
336_L	340_Y	0.835	0.95
332_G	397_L	0.832	0.95
155_Y	411_V	0.831	0.95
19_Q	23_F	0.830	0.95
281_L	353_F	0.829	0.95
301_F	304_I	0.825	0.95
285_A	423_W	0.822	0.94
248_A	253_A	0.821	0.94
332_G	335_I	0.819	0.94
367_L	370_G	0.819	0.94
240_H	243_E	0.818	0.94
241_N	244_V	0.813	0.94
478_T	481_K	0.811	0.94
291_L	392_Q	0.809	0.94
366_I	388_S	0.807	0.94
308_E	379_I	0.807	0.94
336_L	394_I	0.806	0.94
400_S	423_W	0.806	0.94
100_I	104_L	0.801	0.94
405_A	409_Q	0.801	0.94
324_L	328_W	0.798	0.94
293_S	427_T	0.795	0.93
272_R	280_I	0.795	0.93
306_N	457_Y	0.795	0.93
325_N	396_E	0.794	0.93
55_S	59_S	0.793	0.93
298_S	301_F	0.792	0.93
400_S	403_G	0.792	0.93
129_F	133_P	0.789	0.93
172_W	176_K	0.787	0.93
336_L	339_I	0.787	0.93
30_E	159_V	0.785	0.93
17_F	20_P	0.784	0.93
20_P	23_F	0.784	0.93
32_W	35_F	0.783	0.93
332_G	390_G	0.782	0.93
329_I	334_P	0.781	0.93
290_V	433_I	0.780	0.93
460_V	464_I	0.776	0.93
242_Q	249_L	0.776	0.93
351_T	354_A	0.775	0.93
70_V	132_N	0.772	0.92
481_K	485_M	0.768	0.92
244_V	247_M	0.763	0.92
99_A	187_V	0.763	0.92
293_S	431_N	0.762	0.92
43_I	48_L	0.761	0.92
106_A	194_I	0.760	0.92
350_P	484_R	0.758	0.92
215_P	219_R	0.757	0.92
221_L	225_I	0.756	0.92
82_D	86_G	0.754	0.92
33_E	190_L	0.754	0.92
235_A	238_L	0.752	0.91
138_S	152_F	0.752	0.91
204_V	209_S	0.751	0.91
165_F	168_I	0.750	0.91
180_S	184_A	0.748	0.91
433_I	436_Y	0.746	0.91
288_F	325_N	0.746	0.91
155_Y	396_E	0.743	0.91
371_A	458_G	0.743	0.91
200_C	204_V	0.742	0.91
132_N	417_G	0.742	0.91
164_F	327_F	0.741	0.91
309_H	382_V	0.739	0.91
281_L	286_I	0.739	0.91
200_C	203_W	0.738	0.91
335_I	340_Y	0.737	0.91
92_M	194_I	0.737	0.91
174_A	178_G	0.735	0.90
297_T	301_F	0.733	0.90
139_T	416_M	0.733	0.90
245_A	252_V	0.732	0.90
244_V	251_V	0.732	0.90
45_A	60_I	0.731	0.90
410_L	486_T	0.731	0.90
370_G	388_S	0.730	0.90
106_A	184_A	0.728	0.90
368_P	464_I	0.728	0.90
243_E	247_M	0.727	0.90
470_V	477_L	0.727	0.90
240_H	245_A	0.727	0.90
160_N	396_E	0.727	0.90
284_E	475_M	0.726	0.90
164_F	326_P	0.726	0.90
299_L	389_Y	0.726	0.90
295_M	396_E	0.716	0.89
241_N	251_V	0.716	0.89
43_I	182_A	0.716	0.89
240_H	254_F	0.716	0.89
282_M	285_A	0.716	0.89
269_G	279_F	0.715	0.89
239_L	249_L	0.715	0.89
25_L	203_W	0.713	0.89
31_L	159_V	0.712	0.89
154_M	157_M	0.711	0.89
282_M	294_Q	0.708	0.89
47_Y	337_A	0.707	0.89
273_R	278_A	0.707	0.89
43_I	56_E	0.705	0.89
89_R	93_L	0.704	0.89
258_V	263_E	0.704	0.89
134_S	159_V	0.701	0.88
19_Q	22_A	0.700	0.88
54_M	116_Y	0.700	0.88
226_I	229_V	0.699	0.88
430_A	433_I	0.697	0.88
160_N	326_P	0.696	0.88
61_T	65_S	0.695	0.88
372_K	377_A	0.695	0.88
247_M	252_V	0.695	0.88
133_P	159_V	0.694	0.88
169_A	172_W	0.694	0.88
353_F	403_G	0.693	0.88
102_Y	187_V	0.691	0.88
181_V	186_S	0.690	0.88
246_R	254_F	0.689	0.87
354_A	479_A	0.686	0.87
268_K	271_A	0.684	0.87
316_V	382_V	0.683	0.87
281_L	406_M	0.681	0.87
153_T	340_Y	0.680	0.87
246_R	253_A	0.680	0.87
79_W	84_V	0.679	0.87
244_V	254_F	0.677	0.87
161_I	329_I	0.676	0.86
276_I	280_I	0.676	0.86
251_V	254_F	0.676	0.86
167_M	323_A	0.675	0.86
257_V	263_E	0.674	0.86
34_R	126_N	0.674	0.86
77_G	141_Y	0.673	0.86
441_M	463_Q	0.672	0.86
91_I	417_G	0.672	0.86
198_A	201_Q	0.672	0.86
45_A	300_N	0.671	0.86
343_M	346_T	0.670	0.86
155_Y	404_L	0.670	0.86
436_Y	440_M	0.667	0.86
233_A	253_A	0.666	0.86
336_L	397_L	0.664	0.85
129_F	132_N	0.662	0.85
244_V	278_A	0.662	0.85
238_L	243_E	0.662	0.85
46_V	305_R	0.660	0.85
474_L	477_L	0.660	0.85
67_S	70_V	0.660	0.85
75_A	79_W	0.659	0.85
259_I	262_K	0.658	0.85
215_P	218_Y	0.658	0.85
286_I	294_Q	0.657	0.85
288_F	294_Q	0.656	0.85
64_S	435_G	0.653	0.85
277_V	485_M	0.653	0.85
295_M	325_N	0.651	0.84
314_L	317_E	0.648	0.84
291_L	360_C	0.648	0.84
413_Q	416_M	0.648	0.84
95_A	190_L	0.648	0.84
33_E	37_Y	0.646	0.84
243_E	246_R	0.644	0.84
233_A	236_T	0.644	0.84
368_P	458_G	0.642	0.84
177_Y	317_E	0.641	0.83
288_F	329_I	0.641	0.83
248_A	270_A	0.640	0.83
354_A	358_V	0.638	0.83
90_V	128_L	0.637	0.83
242_Q	250_G	0.637	0.83
444_P	456_V	0.635	0.83
465_G	469_A	0.635	0.83
104_L	114_I	0.634	0.83
340_Y	347_L	0.633	0.83
459_R	466_V	0.633	0.83
33_E	294_Q	0.632	0.83
221_L	227_G	0.631	0.82
60_I	301_F	0.630	0.82
174_A	177_Y	0.626	0.82
285_A	289_F	0.626	0.82
370_G	380_V	0.626	0.82
220_N	262_K	0.624	0.82
46_V	49_V	0.624	0.82
243_E	250_G	0.623	0.82
292_Y	325_N	0.623	0.82
135_S	420_M	0.623	0.82
221_L	224_T	0.623	0.82
169_A	173_L	0.621	0.81
246_R	251_V	0.621	0.81
60_I	441_M	0.621	0.81
297_T	438_A	0.619	0.81
282_M	290_V	0.617	0.81
469_A	472_A	0.616	0.81
42_G	166_S	0.615	0.81
237_W	240_H	0.614	0.81
14_L	21_K	0.612	0.81
262_K	266_A	0.611	0.80
49_V	304_I	0.610	0.80
257_V	264_A	0.609	0.80
175_A	319_E	0.608	0.80
270_A	278_A	0.608	0.80
102_Y	190_L	0.608	0.80
92_M	96_I	0.607	0.80
266_A	272_R	0.607	0.80
244_V	248_A	0.607	0.80
72_G	431_N	0.604	0.80
215_P	220_N	0.603	0.80
37_Y	130_K	0.603	0.80
354_A	475_M	0.602	0.79
152_F	411_V	0.600	0.79
291_L	468_T	0.600	0.79
97_V	124_V	0.599	0.79
351_T	476_L	0.599	0.79
69_L	123_A	0.599	0.79
457_Y	460_V	0.598	0.79
131_A	135_S	0.597	0.79
134_S	400_S	0.597	0.79
98_L	122_I	0.596	0.79
160_N	400_S	0.595	0.79
160_N	163_S	0.595	0.79
179_W	183_F	0.595	0.79
228_V	234_I	0.595	0.79
48_L	52_L	0.594	0.79
103_A	107_W	0.594	0.79
152_F	281_L	0.593	0.78
93_L	198_A	0.592	0.78
245_A	253_A	0.592	0.78
225_I	229_V	0.591	0.78
407_V	419_I	0.585	0.77
14_L	17_F	0.585	0.77
25_L	196_N	0.584	0.77
133_P	136_L	0.584	0.77
50_K	304_I	0.584	0.77
290_V	437_V	0.583	0.77
302_F	385_L	0.583	0.77
335_I	338_A	0.582	0.77
233_A	238_L	0.581	0.77
267_M	270_A	0.581	0.77
473_V	481_K	0.580	0.77
156_Y	325_N	0.579	0.77
360_C	468_T	0.579	0.77
281_L	285_A	0.576	0.76
21_K	24_Y	0.574	0.76
71_Y	160_N	0.574	0.76
399_I	423_W	0.574	0.76
166_S	434_G	0.574	0.76
61_T	64_S	0.573	0.76
470_V	474_L	0.573	0.76
142_E	205_K	0.573	0.76
15_N	21_K	0.572	0.76
341_N	344_G	0.572	0.76
228_V	232_I	0.572	0.76
475_M	479_A	0.572	0.76
414_R	421_G	0.571	0.76
235_A	240_H	0.571	0.76
287_I	290_V	0.570	0.76
215_P	221_L	0.570	0.76
220_N	264_A	0.568	0.75
172_W	319_E	0.567	0.75
438_A	441_M	0.566	0.75
286_I	433_I	0.566	0.75
241_N	256_I	0.565	0.75
22_A	26_I	0.565	0.75
33_E	39_G	0.564	0.75
22_A	25_L	0.563	0.75
132_N	186_S	0.563	0.75
38_Y	166_S	0.563	0.75
232_I	237_W	0.562	0.75
110_H	113_G	0.561	0.75
238_L	241_N	0.560	0.74
223_L	227_G	0.558	0.74
81_G	91_I	0.555	0.74
425_L	429_G	0.555	0.74
378_G	381_S	0.554	0.74
306_N	378_G	0.554	0.74
165_F	169_A	0.552	0.73
98_L	125_G	0.552	0.73
71_Y	325_N	0.552	0.73
129_F	155_Y	0.552	0.73
63_F	431_N	0.550	0.73
267_M	280_I	0.549	0.73
38_Y	130_K	0.549	0.73
359_M	398_M	0.548	0.73
174_A	179_W	0.547	0.73
157_M	334_P	0.547	0.73
68_A	432_L	0.547	0.73
42_G	167_M	0.546	0.73
229_V	237_W	0.545	0.72
265_F	268_K	0.544	0.72
132_N	141_Y	0.544	0.72
98_L	102_Y	0.544	0.72
192_I	196_N	0.544	0.72
295_M	389_Y	0.543	0.72
113_G	331_I	0.542	0.72
272_R	277_V	0.542	0.72
197_F	201_Q	0.542	0.72
153_T	337_A	0.542	0.72
288_F	396_E	0.541	0.72
72_G	76_I	0.540	0.72
434_G	464_I	0.539	0.72
91_I	197_F	0.538	0.71
168_I	323_A	0.537	0.71
468_T	472_A	0.536	0.71
30_E	39_G	0.535	0.71
236_T	239_L	0.534	0.71
63_F	119_M	0.533	0.71
33_E	129_F	0.532	0.71
400_S	420_M	0.531	0.70
266_A	270_A	0.530	0.70
268_K	279_F	0.530	0.70
436_Y	439_G	0.528	0.70
362_G	365_L	0.528	0.70
139_T	207_Y	0.528	0.70
34_R	190_L	0.528	0.70
27_F	31_L	0.526	0.70
123_A	430_A	0.525	0.70
34_R	155_Y	0.525	0.70
130_K	190_L	0.524	0.69
441_M	460_V	0.524	0.69
30_E	37_Y	0.523	0.69
288_F	399_I	0.523	0.69
291_L	367_L	0.523	0.69
29_I	158_S	0.523	0.69
226_I	463_Q	0.522	0.69
32_W	36_G	0.522	0.69
244_V	249_L	0.522	0.69
266_A	269_G	0.521	0.69
72_G	430_A	0.520	0.69
289_F	294_Q	0.520	0.69
236_T	241_N	0.519	0.69
156_Y	322_Q	0.519	0.69
292_Y	329_I	0.519	0.69
434_G	460_V	0.518	0.69
242_Q	252_V	0.517	0.68
218_Y	227_G	0.517	0.68
228_V	231_L	0.516	0.68
19_Q	141_Y	0.516	0.68
84_V	105_V	0.515	0.68
22_A	203_W	0.514	0.68
156_Y	159_V	0.512	0.68
37_Y	41_Q	0.512	0.68
242_Q	246_R	0.512	0.68
129_F	134_S	0.512	0.68
404_L	424_F	0.512	0.68
240_H	247_M	0.511	0.68
95_A	186_S	0.510	0.67
182_A	186_S	0.509	0.67
36_G	180_S	0.509	0.67
356_G	395_G	0.507	0.67
252_V	359_M	0.506	0.67
35_F	189_G	0.505	0.67
416_M	421_G	0.505	0.67
268_K	275_M	0.505	0.67
229_V	234_I	0.505	0.67
273_R	276_I	0.503	0.66
60_I	297_T	0.503	0.66
481_K	484_R	0.502	0.66
149_D	352_K	0.501	0.66
151_A	408_A	0.501	0.66
202_R	205_K	0.501	0.66
143_K	148_L	0.501	0.66
289_F	295_M	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4oh3A	2	0.938	100	0.515	Contact Map
4uvmA	1	0.93	100	0.549	Contact Map
4q65A	1	0.854	100	0.594	Contact Map
4tphA	2	0.88	100	0.601	Contact Map
4ikvA	1	0.942	100	0.617	Contact Map
4xnjA	1	0.894	100	0.642	Contact Map
4w6vA	1	0.92	100	0.722	Contact Map
1pw4A	1	0.842	100	0.75	Contact Map
3wdoA	1	0.816	100	0.751	Contact Map
2cfqA	1	0.826	100	0.755	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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