GREMLIN Database
YFCV - Uncharacterized fimbrial-like protein YfcV
UniProt: P77288 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14125
Length: 187 (164)
Sequences: 3188 (2530)
Seq/√Len: 197.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
119_N172_D3.2781.00
123_L162_A3.2241.00
90_M184_I2.9841.00
44_S81_D2.9541.00
76_Q157_T2.9081.00
126_G163_W2.7791.00
124_A163_W2.7561.00
124_A165_V2.7111.00
46_V80_Q2.7101.00
105_N122_S2.5741.00
106_Y135_S2.5091.00
164_L176_F2.4801.00
120_N171_P2.4741.00
130_G161_K2.1481.00
78_R157_T2.1221.00
127_D131_T2.0901.00
76_Q159_N2.0081.00
123_L178_A1.9611.00
144_V147_T1.9351.00
134_K137_M1.9211.00
117_A175_N1.9171.00
124_A132_S1.8841.00
19_T23_T1.8721.00
26_A29_N1.7861.00
74_N161_K1.7841.00
46_V78_R1.7381.00
46_V49_D1.7131.00
106_Y180_T1.6981.00
37_T58_D1.6161.00
114_T117_A1.6001.00
69_T124_A1.5591.00
20_S24_I1.5581.00
105_N165_V1.5571.00
72_P163_W1.5281.00
64_L166_G1.5041.00
59_I70_T1.4681.00
74_N159_N1.4231.00
57_G176_F1.4031.00
69_T163_W1.3761.00
95_T183_Q1.3651.00
56_M164_L1.3631.00
49_D52_L1.3071.00
49_D78_R1.3051.00
96_G106_Y1.3041.00
12_A15_M1.3001.00
75_F125_I1.2931.00
57_G73_K1.2911.00
104_G134_K1.2911.00
91_T185_T1.2821.00
95_T136_G1.2751.00
99_S167_A1.2471.00
105_N124_A1.2461.00
69_T126_G1.2431.00
96_G99_S1.2341.00
57_G71_T1.2311.00
52_L77_I1.2231.00
69_T165_V1.2091.00
92_T158_L1.2061.00
22_A26_A1.1861.00
30_G182_F1.1741.00
166_G171_P1.1701.00
30_G34_F1.1661.00
20_S23_T1.1581.00
56_M176_F1.1451.00
64_L121_V1.1311.00
90_M156_Q1.1251.00
44_S80_Q1.1231.00
64_L171_P1.1181.00
63_K70_T1.1121.00
118_F121_V1.0991.00
128_S159_N1.0961.00
93_T185_T1.0571.00
17_A20_S1.0491.00
166_G170_A1.0391.00
98_V104_G1.0321.00
33_R179_N1.0241.00
99_S122_S1.0071.00
38_I171_P0.9971.00
72_P161_K0.9891.00
121_V164_L0.9881.00
47_P52_L0.9881.00
67_N169_D0.9780.99
144_V156_Q0.9620.99
59_I164_L0.9540.99
10_A13_M0.9540.99
106_Y178_A0.9530.99
18_F22_A0.9490.99
125_I180_T0.9470.99
40_D61_A0.9390.99
31_T51_K0.9280.99
21_T24_I0.9250.99
52_L182_F0.9190.99
67_N166_G0.9120.99
13_M16_G0.9090.99
20_S25_A0.9070.99
102_N105_N0.9050.99
15_M18_F0.9010.99
40_D83_V0.8890.99
100_S122_S0.8870.99
59_I64_L0.8860.99
99_S107_Y0.8830.99
11_A15_M0.8780.99
77_I182_F0.8750.99
35_Y53_E0.8670.99
99_S103_S0.8660.99
109_I176_F0.8630.99
64_L167_A0.8620.99
93_T138_G0.8590.99
123_L176_F0.8530.99
65_K166_G0.8520.99
59_I176_F0.8510.99
38_I59_I0.8370.98
16_G19_T0.8370.98
103_S106_Y0.8360.98
116_A175_N0.8360.98
54_V75_F0.8150.98
12_A20_S0.8130.98
126_G161_K0.8130.98
60_G63_K0.8130.98
166_G169_D0.8080.98
133_Y139_I0.8050.98
66_N166_G0.8030.98
79_L156_Q0.7930.98
42_V164_L0.7900.98
139_I160_F0.7880.98
14_V17_A0.7840.98
17_A21_T0.7830.98
89_T141_Q0.7820.98
35_Y55_D0.7800.97
125_I135_S0.7760.97
94_F125_I0.7750.97
143_I147_T0.7750.97
19_T22_A0.7740.97
98_V135_S0.7700.97
33_R51_K0.7690.97
70_T164_L0.7660.97
143_I146_D0.7570.97
114_T175_N0.7550.97
10_A22_A0.7540.97
56_M123_L0.7530.97
61_A173_L0.7490.97
94_F160_F0.7490.97
84_F87_Q0.7440.97
95_T181_T0.7430.97
126_G132_S0.7430.97
56_M162_A0.7380.96
122_S167_A0.7360.96
21_T26_A0.7330.96
12_A16_G0.7320.96
91_T139_I0.7290.96
21_T25_A0.7180.96
100_S103_S0.7170.96
16_G21_T0.7120.96
89_T143_I0.7080.96
56_M124_A0.7060.95
40_D86_T0.7000.95
69_T72_P0.7000.95
92_T184_I0.6970.95
53_E181_T0.6950.95
131_T140_D0.6940.95
79_L90_M0.6870.95
22_A25_A0.6860.95
91_T138_G0.6830.95
11_A19_T0.6810.95
126_G130_G0.6800.94
64_L169_D0.6750.94
83_V86_T0.6700.94
109_I164_L0.6690.94
49_D125_I0.6680.94
33_R53_E0.6650.94
135_S180_T0.6640.94
83_V126_G0.6610.94
97_T107_Y0.6610.94
18_F23_T0.6570.93
56_M73_K0.6550.93
56_M70_T0.6530.93
16_G20_S0.6460.93
48_D78_R0.6460.93
16_G23_T0.6460.93
132_S135_S0.6390.92
114_T177_E0.6360.92
107_Y122_S0.6360.92
72_P126_G0.6360.92
55_D73_K0.6350.92
120_N167_A0.6330.92
32_A180_T0.6310.92
55_D164_L0.6310.92
47_P50_H0.6310.92
90_M139_I0.6280.92
13_M21_T0.6270.92
20_S26_A0.6260.92
24_I28_N0.6220.91
147_T156_Q0.6210.91
67_N120_N0.6200.91
93_T137_M0.6110.91
121_V171_P0.6100.91
57_G177_E0.6060.90
42_V87_Q0.6040.90
145_K156_Q0.6000.90
135_S178_A0.5940.89
37_T175_N0.5930.89
15_M19_T0.5890.89
18_F21_T0.5870.89
23_T26_A0.5870.89
15_M20_S0.5860.89
64_L67_N0.5850.89
32_A75_F0.5790.88
28_N31_T0.5760.88
54_V162_A0.5760.88
39_E83_V0.5760.88
61_A171_P0.5740.88
42_V84_F0.5730.88
135_S160_F0.5710.88
67_N171_P0.5700.87
10_A15_M0.5640.87
141_Q148_A0.5600.87
103_S107_Y0.5560.86
160_F182_F0.5560.86
67_N168_A0.5550.86
14_V23_T0.5540.86
32_A53_E0.5510.86
140_D143_I0.5510.86
63_K71_T0.5430.85
92_T156_Q0.5410.85
28_N34_F0.5390.84
98_V179_N0.5380.84
121_V176_F0.5360.84
10_A14_V0.5340.84
94_F158_L0.5290.83
27_G31_T0.5290.83
75_F162_A0.5270.83
30_G37_T0.5240.83
121_V166_G0.5200.82
40_D160_F0.5200.82
128_S145_K0.5200.82
137_M146_D0.5180.82
14_V20_S0.5170.82
99_S102_N0.5150.82
19_T24_I0.5150.82
161_K178_A0.5150.82
140_D184_I0.5090.81
10_A18_F0.5080.81
109_I116_A0.5060.81
38_I176_F0.5040.80
65_K171_P0.5030.80
10_A21_T0.5000.80
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jmrA 1 0.8075 100 0.292 Contact Map
2xg5B 1 0.7487 100 0.31 Contact Map
2jtyA 1 0.8289 100 0.316 Contact Map
2uy6B 2 0.7701 100 0.32 Contact Map
1pdkB 1 0.738 100 0.341 Contact Map
3bwuF 1 0.6631 99.9 0.395 Contact Map
2w07B 1 0.6257 99.9 0.4 Contact Map
4dwhB 1 0.7166 99.9 0.417 Contact Map
3bfqG 1 0.7005 99.9 0.433 Contact Map
5afoA 1 0.9358 99.9 0.439 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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