GREMLIN Database
YDJJ - Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ
UniProt: P77280 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13486
Length: 347 (302)
Sequences: 52893 (36488)
Seq/√Len: 2099.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_E145_T2.9991.00
32_K72_V2.9111.00
34_E70_T2.8281.00
323_D326_Q2.6951.00
9_Q17_I2.6681.00
171_K195_E2.5591.00
30_L72_V2.4561.00
82_K85_D2.4441.00
86_R139_L2.3291.00
85_D138_K2.3291.00
29_V136_T2.2701.00
144_D147_E2.2681.00
21_I128_Y2.2371.00
146_M318_I2.2251.00
9_Q15_K2.2231.00
177_A198_V2.2041.00
189_K215_T2.1841.00
32_K128_Y2.1491.00
319_Y330_E2.1441.00
32_K70_T2.1211.00
172_I188_C2.1071.00
317_H330_E2.0971.00
7_I17_I2.0971.00
228_R231_Q2.0841.00
67_C124_A2.0831.00
318_I344_K2.0721.00
167_K170_K2.0311.00
67_C89_I2.0171.00
206_L210_E1.9981.00
162_M191_L1.9901.00
25_K28_E1.9871.00
26_E76_S1.9861.00
26_E77_R1.9611.00
80_K133_E1.9381.00
142_N305_S1.9351.00
30_L130_C1.9251.00
195_E216_V1.8921.00
72_V128_Y1.8851.00
185_L214_A1.8851.00
47_E332_V1.8681.00
27_D77_R1.8681.00
86_R145_T1.8131.00
302_E306_S1.8071.00
329_E333_N1.7961.00
207_A211_Q1.7811.00
154_A183_M1.7711.00
320_D323_D1.7711.00
68_A145_T1.7311.00
190_C308_R1.7151.00
263_K286_T1.7141.00
207_A210_E1.7011.00
162_M299_V1.6781.00
239_D259_M1.6771.00
330_E335_K1.6761.00
173_I199_V1.6751.00
206_L217_V1.6661.00
173_I238_A1.6521.00
208_M211_Q1.6441.00
263_K288_Q1.6431.00
139_L145_T1.6371.00
326_Q329_E1.5951.00
197_A238_A1.5741.00
23_V73_A1.5671.00
200_D206_L1.5641.00
326_Q330_E1.5591.00
216_V232_F1.5421.00
30_L128_Y1.5331.00
6_A324_V1.5331.00
70_T86_R1.5311.00
319_Y327_A1.5301.00
139_L148_G1.5161.00
4_S18_S1.5031.00
195_E215_T1.4971.00
203_E219_N1.4881.00
258_V264_I1.4841.00
203_E207_A1.4831.00
73_A83_P1.4581.00
175_L254_A1.4511.00
74_V83_P1.4491.00
30_L73_A1.4491.00
81_F85_D1.4391.00
241_V258_V1.4301.00
203_E222_K1.4291.00
125_L328_F1.4141.00
164_A240_I1.4121.00
147_E312_K1.4111.00
146_M344_K1.4081.00
325_Q329_E1.4051.00
258_V285_V1.4011.00
27_D132_P1.4011.00
81_F138_K1.3931.00
219_N222_K1.3921.00
28_E132_P1.3901.00
33_V67_C1.3871.00
258_V262_G1.3811.00
5_K19_A1.3731.00
28_E130_C1.3681.00
170_K263_K1.3501.00
241_V254_A1.3371.00
75_G78_V1.3361.00
24_P130_C1.3341.00
224_D227_A1.3311.00
223_E228_R1.3281.00
4_S322_R1.3221.00
35_Y146_M1.3031.00
203_E206_L1.2981.00
86_R141_D1.2941.00
190_C303_A1.2931.00
158_M162_M1.2931.00
70_T145_T1.2831.00
29_V81_F1.2761.00
24_P30_L1.2741.00
302_E305_S1.2741.00
6_A16_I1.2721.00
316_T330_E1.2721.00
201_V220_G1.2691.00
71_V81_F1.2671.00
171_K197_A1.2391.00
34_E86_R1.2291.00
46_F328_F1.2281.00
227_A231_Q1.2271.00
228_R232_F1.2191.00
320_D344_K1.2081.00
211_Q313_S1.2041.00
175_L199_V1.2021.00
184_T242_F1.2011.00
33_V129_L1.1871.00
151_V304_I1.1671.00
4_S127_H1.1661.00
21_I30_L1.1571.00
185_L198_V1.1461.00
81_F136_T1.1241.00
171_K239_D1.1231.00
206_L219_N1.1221.00
10_V13_T1.1181.00
27_D133_E1.1091.00
303_A308_R1.1081.00
226_I256_Y1.1051.00
210_E217_V1.0991.00
166_V193_A1.0951.00
299_V302_E1.0931.00
35_Y344_K1.0891.00
224_D228_R1.0771.00
7_I19_A1.0651.00
170_K239_D1.0621.00
256_Y280_K1.0561.00
131_H136_T1.0471.00
201_V206_L1.0421.00
208_M338_I1.0401.00
324_V343_I1.0211.00
226_I253_Q1.0191.00
157_G184_T1.0181.00
159_H296_R1.0181.00
31_I87_V1.0171.00
35_Y145_T1.0091.00
188_C193_A1.0081.00
197_A216_V1.0031.00
166_V170_K1.0021.00
78_V133_E1.0011.00
163_L286_T0.9971.00
46_F332_V0.9971.00
210_E216_V0.9901.00
31_I69_G0.9851.00
164_A265_M0.9791.00
329_E332_V0.9781.00
162_M296_R0.9761.00
16_I322_R0.9751.00
253_Q256_Y0.9741.00
72_V83_P0.9731.00
245_A250_T0.9721.00
36_V125_L0.9651.00
24_P28_E0.9631.00
226_I230_Q0.9621.00
38_I327_A0.9601.00
298_P302_E0.9561.00
6_A321_Y0.9541.00
319_Y323_D0.9521.00
158_M299_V0.9511.00
160_A267_V0.9401.00
299_V303_A0.9371.00
198_V209_A0.9351.00
177_A200_D0.9341.00
330_E341_G0.9231.00
163_L288_Q0.9221.00
157_G187_A0.9161.00
170_K240_I0.9141.00
9_Q13_T0.9111.00
154_A300_T0.9111.00
201_V221_A0.9101.00
160_A242_F0.9091.00
35_Y342_V0.9091.00
202_L205_R0.9071.00
177_A185_L0.9031.00
79_R133_E0.9031.00
177_A209_A0.8961.00
11_P59_Q0.8931.00
36_V124_A0.8931.00
43_V331_S0.8921.00
4_S16_I0.8921.00
61_I122_R0.8901.00
252_K256_Y0.8891.00
222_K228_R0.8881.00
198_V214_A0.8851.00
182_L208_M0.8781.00
205_R338_I0.8751.00
34_E68_A0.8731.00
88_N301_I0.8711.00
74_V82_K0.8631.00
39_C66_E0.8551.00
19_A122_R0.8551.00
229_C238_A0.8511.00
185_L196_I0.8481.00
125_L324_V0.8471.00
204_K207_A0.8451.00
143_M148_G0.8421.00
199_V220_G0.8361.00
197_A218_I0.8361.00
6_A14_M0.8351.00
261_G284_E0.8341.00
175_L241_V0.8341.00
243_E246_G0.8331.00
173_I257_L0.8301.00
21_I73_A0.8281.00
7_I62_G0.8251.00
74_V78_V0.8231.00
5_K62_G0.8211.00
233_T237_G0.8211.00
174_I188_C0.8141.00
32_K127_H0.8131.00
137_Y298_P0.8081.00
280_K283_R0.8071.00
67_C129_L0.8001.00
225_T253_Q0.7971.00
21_I72_V0.7901.00
295_N299_V0.7891.00
155_A296_R0.7881.00
209_A214_A0.7871.00
165_D263_K0.7871.00
188_C196_I0.7821.00
241_V264_I0.7821.00
29_V133_E0.7781.00
39_C65_H0.7781.00
37_G66_E0.7761.00
191_L299_V0.7721.00
89_I131_H0.7681.00
200_D217_V0.7681.00
141_D305_S0.7651.00
174_I184_T0.7651.00
244_T267_V0.7601.00
187_A300_T0.7601.00
124_A129_L0.7601.00
172_I193_A0.7581.00
47_E50_P0.7561.00
254_A264_I0.7551.00
317_H326_Q0.7551.00
303_A306_S0.7541.00
82_K138_K0.7541.00
252_K280_K0.7511.00
197_A232_F0.7501.00
38_I331_S0.7491.00
175_L250_T0.7491.00
19_A62_G0.7481.00
25_K130_C0.7441.00
319_Y341_G0.7441.00
125_L343_I0.7411.00
227_A230_Q0.7411.00
281_I287_I0.7411.00
39_C42_D0.7391.00
171_K238_A0.7381.00
16_I321_Y0.7331.00
196_I215_T0.7321.00
201_V209_A0.7321.00
197_A229_C0.7321.00
171_K236_M0.7311.00
295_N298_P0.7301.00
23_V30_L0.7281.00
330_E333_N0.7251.00
161_A188_C0.7231.00
226_I257_L0.7181.00
6_A325_Q0.7171.00
87_V136_T0.7131.00
301_I305_S0.7101.00
315_V318_I0.7101.00
68_A149_A0.7071.00
165_D286_T0.7031.00
157_G183_M0.7031.00
187_A303_A0.6991.00
88_N139_L0.6981.00
143_M304_I0.6951.00
43_V332_V0.6931.00
41_S65_H0.6921.00
266_I287_I0.6911.00
160_A184_T0.6861.00
27_D76_S0.6831.00
281_I285_V0.6821.00
193_A240_I0.6811.00
166_V240_I0.6801.00
337_D341_G0.6791.00
27_D75_G0.6781.00
159_H284_E0.6771.00
24_P73_A0.6751.00
233_T236_M0.6711.00
331_S341_G0.6691.00
158_M303_A0.6691.00
58_N61_I0.6671.00
225_T229_C0.6651.00
140_P305_S0.6621.00
224_D253_Q0.6581.00
29_V71_V0.6571.00
319_Y343_I0.6521.00
24_P75_G0.6511.00
33_V36_V0.6511.00
22_P130_C0.6501.00
216_V228_R0.6501.00
208_M212_L0.6501.00
174_I198_V0.6491.00
165_D288_Q0.6471.00
202_L219_N0.6461.00
243_E264_I0.6441.00
162_M187_A0.6431.00
185_L212_L0.6431.00
240_I265_M0.6371.00
57_P61_I0.6361.00
85_D141_D0.6341.00
273_D277_N0.6341.00
303_A307_G0.6341.00
137_Y297_Y0.6331.00
186_Q212_L0.6331.00
252_K273_D0.6321.00
88_N152_E0.6301.00
238_A241_V0.6291.00
27_D134_S0.6291.00
247_S250_T0.6281.00
251_V264_I0.6281.00
240_I263_K0.6271.00
277_N280_K0.6261.00
193_A196_I0.6251.00
214_A217_V0.6241.00
137_Y301_I0.6221.00
158_M296_R0.6221.00
68_A139_L0.6211.00
157_G180_I0.6211.00
189_K196_I0.6191.00
157_G161_A0.6181.00
234_E237_G0.6181.00
330_E337_D0.6171.00
41_S45_G0.6171.00
12_G46_F0.6161.00
317_H341_G0.6151.00
156_V180_I0.6131.00
35_Y68_A0.6101.00
90_E137_Y0.6071.00
68_A86_R0.6061.00
13_T325_Q0.6001.00
218_I232_F0.6001.00
296_R299_V0.5991.00
248_A252_K0.5991.00
151_V300_T0.5981.00
35_Y318_I0.5971.00
65_H153_P0.5971.00
158_M300_T0.5961.00
34_E344_K0.5941.00
184_T267_V0.5911.00
281_I289_T0.5911.00
168_P192_G0.5881.00
89_I136_T0.5861.00
43_V47_E0.5841.00
297_Y301_I0.5831.00
317_H338_I0.5821.00
31_I89_I0.5821.00
260_R283_R0.5821.00
8_L13_T0.5801.00
218_I228_R0.5791.00
252_K275_A0.5781.00
273_D276_I0.5771.00
86_R142_N0.5771.00
81_F133_E0.5751.00
160_A265_M0.5721.00
38_I125_L0.5691.00
236_M259_M0.5651.00
150_L342_V0.5631.00
168_P191_L0.5621.00
10_V15_K0.5621.00
238_A257_L0.5611.00
229_C257_L0.5601.00
40_G44_H0.5601.00
39_C153_P0.5591.00
41_S44_H0.5571.00
164_A263_K0.5571.00
159_H163_L0.5531.00
39_C340_K0.5531.00
31_I136_T0.5531.00
171_K233_T0.5511.00
36_V343_I0.5511.00
200_D219_N0.5491.00
132_P135_F0.5481.00
211_Q312_K0.5471.00
80_K83_P0.5471.00
11_P48_S0.5471.00
173_I241_V0.5461.00
74_V85_D0.5461.00
14_M328_F0.5461.00
187_A191_L0.5461.00
22_P128_Y0.5451.00
200_D209_A0.5451.00
328_F332_V0.5451.00
22_P28_E0.5441.00
200_D220_G0.5421.00
38_I343_I0.5411.00
79_R82_K0.5401.00
230_Q237_G0.5391.00
172_I240_I0.5371.00
230_Q233_T0.5361.00
250_T253_Q0.5351.00
317_H323_D0.5341.00
64_G125_L0.5341.00
182_L212_L0.5331.00
231_Q234_E0.5321.00
93_V135_F0.5301.00
241_V257_L0.5291.00
183_M187_A0.5271.00
161_A187_A0.5271.00
185_L209_A0.5261.00
206_L209_A0.5261.00
319_Y326_Q0.5231.00
250_T254_A0.5221.00
133_E136_T0.5221.00
265_M290_V0.5211.00
316_T339_I0.5201.00
312_K315_V0.5191.00
186_Q309_F0.5181.00
327_A343_I0.5151.00
183_M309_F0.5141.00
282_N291_F0.5141.00
156_V267_V0.5141.00
160_A290_V0.5131.00
21_I130_C0.5131.00
298_P301_I0.5131.00
251_V266_I0.5131.00
20_E23_V0.5091.00
174_I185_L0.5081.00
33_V89_I0.5071.00
200_D205_R0.5071.00
89_I124_A0.5071.00
66_E153_P0.5071.00
56_D59_Q0.5061.00
66_E340_K0.5061.00
233_T238_A0.5041.00
80_K138_K0.5011.00
144_D148_G0.5011.00
171_K216_V0.5011.00
265_M288_Q0.5011.00
159_H290_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ilkA 2 0.9654 100 0.156 Contact Map
4ej6A 1 0.9683 100 0.156 Contact Map
3m6iA 4 0.9856 100 0.162 Contact Map
3ukoA 4 0.9798 100 0.165 Contact Map
2dq4A 4 0.9712 100 0.166 Contact Map
1e3iA 2 0.9712 100 0.167 Contact Map
3ip1A 4 0.9741 100 0.174 Contact Map
1cdoA 2 0.9741 100 0.175 Contact Map
1f8fA 4 0.9683 100 0.178 Contact Map
1e3jA 4 0.9856 100 0.178 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.011 seconds.