PTYBC - ECOLI - GREMLIN Contacts

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PTYBC - PTS system N-acetylmuramic acid-specific EIIBC component

UniProt:	P77272	Sequences: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNLD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14163
Length:	474 (438)
Sequences:	3711 (2188)
Seq/√Len:	104.5

ECOLI - PTYBC PTV3B PTTBC PTIBC PTGCB PTOCB
BACSU - PTV3B PTSBC PTTBC PTXBC SACX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
407_F	454_V	4.104	1.00
400_G	458_C	3.883	1.00
305_G	402_A	3.774	1.00
8_E	12_T	3.689	1.00
352_A	460_F	3.451	1.00
45_P	48_K	3.426	1.00
235_A	271_A	3.411	1.00
37_V	43_V	3.281	1.00
262_I	266_I	3.178	1.00
14_L	79_M	3.093	1.00
40_S	58_L	3.090	1.00
16_R	44_D	2.939	1.00
9_L	50_L	2.932	1.00
178_G	192_G	2.872	1.00
407_F	447_V	2.871	1.00
51_E	362_A	2.847	1.00
239_C	263_T	2.726	1.00
403_A	458_C	2.696	1.00
39_D	42_L	2.642	1.00
55_G	66_V	2.545	1.00
7_S	11_N	2.518	1.00
346_Q	387_T	2.515	1.00
107_T	112_Q	2.508	1.00
250_M	258_L	2.491	1.00
396_T	466_F	2.426	1.00
179_Y	193_A	2.414	1.00
20_P	84_G	2.408	1.00
78_A	81_E	2.380	1.00
24_A	38_H	2.377	1.00
35_L	65_V	2.369	1.00
245_M	249_F	2.321	1.00
326_L	333_N	2.319	1.00
246_V	262_I	2.287	1.00
16_R	46_N	2.274	1.00
247_R	255_D	2.246	1.00
407_F	411_I	2.233	1.00
7_S	78_A	2.225	1.00
16_R	50_L	2.209	1.00
411_I	447_V	2.208	1.00
238_A	270_L	2.204	1.00
449_A	453_L	2.181	1.00
35_L	79_M	2.156	1.00
17_V	35_L	2.149	1.00
78_A	82_L	2.121	1.00
179_Y	189_G	2.099	1.00
175_I	197_A	2.051	1.00
26_C	79_M	2.045	1.00
304_A	401_G	2.035	1.00
357_A	363_L	2.004	1.00
12_T	50_L	1.953	1.00
11_N	82_L	1.943	1.00
14_L	83_L	1.914	1.00
26_C	35_L	1.908	1.00
254_L	258_L	1.908	1.00
137_I	141_I	1.900	1.00
116_K	185_F	1.895	1.00
13_I	47_I	1.883	1.00
348_G	459_G	1.815	1.00
408_I	451_G	1.773	1.00
396_T	462_F	1.770	1.00
461_I	465_L	1.757	1.00
25_S	36_G	1.752	1.00
354_Y	368_R	1.749	1.00
12_T	15_T	1.744	1.00
241_R	244_G	1.738	1.00
281_W	285_G	1.737	1.00
447_V	450_G	1.736	1.00
348_G	456_W	1.732	1.00
28_N	76_A	1.707	1.00
462_F	466_F	1.702	1.00
175_I	193_A	1.696	1.00
351_L	371_I	1.687	1.00
347_V	374_G	1.682	1.00
46_N	49_T	1.673	1.00
135_L	167_K	1.657	1.00
241_R	245_M	1.643	1.00
141_I	146_H	1.636	1.00
234_I	279_G	1.631	1.00
47_I	50_L	1.630	1.00
458_C	462_F	1.624	1.00
246_V	250_M	1.619	1.00
395_V	399_L	1.616	1.00
76_A	80_S	1.614	1.00
187_G	236_A	1.605	1.00
301_A	406_L	1.601	1.00
11_N	15_T	1.595	1.00
390_R	393_P	1.581	1.00
350_A	382_L	1.580	1.00
57_I	66_V	1.570	1.00
13_I	67_F	1.557	1.00
300_C	405_G	1.556	1.00
258_L	262_I	1.546	1.00
242_I	267_T	1.546	1.00
383_I	394_F	1.542	1.00
10_L	79_M	1.536	1.00
183_Q	189_G	1.533	1.00
396_T	400_G	1.527	1.00
115_A	184_A	1.519	1.00
332_F	414_W	1.514	1.00
309_I	398_C	1.505	1.00
457_V	461_I	1.503	1.00
109_G	112_Q	1.481	1.00
17_V	37_V	1.478	1.00
237_W	240_A	1.464	1.00
285_G	289_L	1.461	1.00
23_I	85_E	1.458	1.00
308_L	343_G	1.455	1.00
284_E	288_W	1.449	1.00
133_L	261_L	1.427	1.00
181_A	237_W	1.416	1.00
430_V	433_P	1.410	1.00
45_P	58_L	1.400	1.00
305_G	309_I	1.395	1.00
182_A	236_A	1.384	1.00
242_I	266_I	1.379	1.00
406_L	410_L	1.368	1.00
179_Y	190_V	1.362	1.00
217_D	220_G	1.357	0.99
353_L	357_A	1.356	0.99
14_L	82_L	1.339	0.99
237_W	241_R	1.329	0.99
390_R	468_C	1.326	0.99
422_S	426_P	1.323	0.99
161_F	223_I	1.320	0.99
26_C	80_S	1.316	0.99
238_A	275_I	1.307	0.99
301_A	402_A	1.303	0.99
300_C	406_L	1.284	0.99
400_G	459_G	1.279	0.99
352_A	464_T	1.275	0.99
109_G	113_F	1.257	0.99
16_R	47_I	1.248	0.99
340_S	448_Y	1.248	0.99
47_I	63_V	1.248	0.99
255_D	259_T	1.227	0.99
356_R	467_G	1.217	0.99
460_F	464_T	1.210	0.99
403_A	454_V	1.209	0.99
23_I	83_L	1.209	0.99
399_L	462_F	1.207	0.99
192_G	196_A	1.205	0.99
407_F	451_G	1.201	0.99
40_S	61_D	1.195	0.99
289_L	292_H	1.193	0.99
363_L	390_R	1.189	0.99
407_F	450_G	1.186	0.99
9_L	52_G	1.161	0.98
427_S	430_V	1.157	0.98
186_G	244_G	1.152	0.98
292_H	295_S	1.149	0.98
392_K	467_G	1.147	0.98
177_V	229_I	1.145	0.98
195_I	264_L	1.143	0.98
121_F	229_I	1.138	0.98
187_G	239_C	1.138	0.98
300_C	409_G	1.136	0.98
14_L	23_I	1.135	0.98
12_T	46_N	1.134	0.98
124_L	173_L	1.133	0.98
463_T	467_G	1.128	0.98
383_I	397_A	1.128	0.98
182_A	189_G	1.125	0.98
286_M	310_A	1.123	0.98
196_A	232_V	1.122	0.98
245_M	248_R	1.118	0.98
180_N	190_V	1.117	0.98
47_I	53_V	1.112	0.98
267_T	271_A	1.109	0.98
131_A	169_L	1.108	0.98
10_L	82_L	1.101	0.98
20_P	83_L	1.101	0.98
182_A	187_G	1.099	0.98
246_V	259_T	1.096	0.98
167_K	171_T	1.093	0.98
165_F	268_A	1.093	0.98
427_S	435_M	1.092	0.98
215_F	220_G	1.092	0.98
182_A	192_G	1.092	0.98
236_A	240_A	1.087	0.98
134_L	166_S	1.087	0.98
427_S	431_A	1.086	0.98
341_M	408_I	1.085	0.98
185_F	237_W	1.083	0.98
67_F	75_A	1.073	0.97
195_I	232_V	1.073	0.97
400_G	404_G	1.072	0.97
238_A	267_T	1.071	0.97
348_G	352_A	1.069	0.97
79_M	83_L	1.069	0.97
140_L	144_V	1.065	0.97
7_S	82_L	1.058	0.97
8_E	11_N	1.052	0.97
50_L	53_V	1.051	0.97
77_K	81_E	1.047	0.97
230_I	234_I	1.046	0.97
404_G	455_A	1.044	0.97
355_W	460_F	1.041	0.97
290_F	334_S	1.039	0.97
371_I	375_L	1.036	0.97
79_M	82_L	1.036	0.97
181_A	233_L	1.030	0.97
188_T	243_E	1.030	0.97
282_L	285_G	1.028	0.97
454_V	458_C	1.023	0.96
70_G	252_D	1.020	0.96
119_T	184_A	1.020	0.96
138_A	159_L	1.016	0.96
198_L	268_A	1.016	0.96
30_M	378_V	1.010	0.96
353_L	363_L	1.004	0.96
285_G	288_W	1.003	0.96
349_A	387_T	1.002	0.96
310_A	319_F	1.002	0.96
124_L	180_N	1.002	0.96
274_I	278_L	1.001	0.96
45_P	63_V	0.998	0.96
70_G	74_R	0.997	0.96
187_G	192_G	0.995	0.96
348_G	375_L	0.995	0.96
40_S	63_V	0.994	0.96
334_S	337_P	0.994	0.96
356_R	468_C	0.994	0.96
396_T	463_T	0.993	0.96
279_G	283_F	0.988	0.96
240_A	244_G	0.985	0.96
369_G	373_P	0.984	0.96
185_F	240_A	0.984	0.96
13_I	50_L	0.984	0.96
426_P	430_V	0.983	0.96
387_T	393_P	0.981	0.96
7_S	81_E	0.980	0.96
120_I	233_L	0.978	0.95
181_A	185_F	0.976	0.95
294_N	297_P	0.974	0.95
15_T	46_N	0.974	0.95
172_F	202_G	0.974	0.95
178_G	232_V	0.969	0.95
444_A	447_V	0.969	0.95
301_A	403_A	0.967	0.95
80_S	85_E	0.965	0.95
73_H	77_K	0.962	0.95
168_G	197_A	0.961	0.95
446_A	450_G	0.960	0.95
349_A	397_A	0.958	0.95
195_I	267_T	0.957	0.95
230_I	279_G	0.951	0.95
446_A	449_A	0.950	0.95
116_K	120_I	0.950	0.95
345_G	397_A	0.946	0.95
176_L	194_I	0.945	0.95
207_A	216_H	0.943	0.94
281_W	284_E	0.940	0.94
433_P	436_T	0.940	0.94
9_L	13_I	0.939	0.94
106_Q	112_Q	0.937	0.94
177_V	232_V	0.934	0.94
351_L	355_W	0.933	0.94
423_A	426_P	0.933	0.94
56_V	63_V	0.932	0.94
24_A	36_G	0.923	0.94
158_A	161_F	0.909	0.93
456_W	459_G	0.907	0.93
37_V	63_V	0.900	0.93
252_D	255_D	0.900	0.93
411_I	454_V	0.898	0.93
148_P	156_P	0.894	0.93
393_P	396_T	0.893	0.93
325_A	329_S	0.891	0.93
105_K	109_G	0.890	0.93
404_G	454_V	0.890	0.93
346_Q	397_A	0.889	0.93
344_A	347_V	0.887	0.92
10_L	78_A	0.886	0.92
349_A	393_P	0.882	0.92
218_F	273_L	0.880	0.92
425_G	434_L	0.877	0.92
392_K	469_R	0.876	0.92
165_F	198_L	0.874	0.92
200_L	226_R	0.869	0.92
167_K	201_L	0.868	0.92
217_D	222_P	0.861	0.91
342_A	346_Q	0.859	0.91
275_I	279_G	0.858	0.91
175_I	196_A	0.858	0.91
348_G	455_A	0.855	0.91
319_F	323_Y	0.854	0.91
247_R	259_T	0.853	0.91
363_L	367_V	0.850	0.91
58_L	63_V	0.850	0.91
353_L	386_V	0.849	0.91
234_I	275_I	0.848	0.91
300_C	338_I	0.847	0.91
242_I	246_V	0.846	0.91
17_V	63_V	0.846	0.91
250_M	254_L	0.845	0.91
48_K	389_P	0.845	0.91
101_Q	104_A	0.844	0.90
354_Y	364_R	0.843	0.90
131_A	168_G	0.842	0.90
361_S	364_R	0.841	0.90
363_L	386_V	0.840	0.90
278_L	282_L	0.840	0.90
307_F	338_I	0.831	0.90
238_A	242_I	0.829	0.90
178_G	236_A	0.828	0.90
393_P	463_T	0.827	0.90
12_T	51_E	0.826	0.90
149_A	155_L	0.826	0.90
354_Y	367_V	0.825	0.89
186_G	192_G	0.825	0.89
454_V	457_V	0.820	0.89
300_C	304_A	0.819	0.89
270_L	275_I	0.818	0.89
225_P	231_G	0.816	0.89
113_F	116_K	0.816	0.89
41_S	44_D	0.815	0.89
304_A	405_G	0.814	0.89
353_L	367_V	0.814	0.89
387_T	397_A	0.811	0.89
28_N	72_A	0.810	0.89
374_G	379_G	0.807	0.88
408_I	413_W	0.806	0.88
47_I	65_V	0.806	0.88
26_C	83_L	0.805	0.88
178_G	193_A	0.805	0.88
427_S	434_L	0.803	0.88
12_T	16_R	0.803	0.88
309_I	394_F	0.803	0.88
105_K	112_Q	0.799	0.88
43_V	56_V	0.798	0.88
455_A	459_G	0.798	0.88
325_A	328_D	0.797	0.88
223_I	273_L	0.792	0.87
430_V	435_M	0.790	0.87
187_G	243_E	0.789	0.87
74_R	252_D	0.785	0.87
422_S	427_S	0.784	0.87
66_V	384_Y	0.784	0.87
386_V	390_R	0.783	0.87
250_M	259_T	0.783	0.87
427_S	433_P	0.781	0.87
46_N	50_L	0.781	0.87
392_K	468_C	0.776	0.86
8_E	51_E	0.770	0.86
178_G	196_A	0.770	0.86
110_V	113_F	0.768	0.86
43_V	63_V	0.768	0.86
356_R	464_T	0.767	0.86
345_G	349_A	0.763	0.85
306_L	398_C	0.762	0.85
105_K	108_S	0.759	0.85
15_T	44_D	0.756	0.85
169_L	176_L	0.755	0.85
251_P	254_L	0.754	0.85
403_A	407_F	0.750	0.84
379_G	382_L	0.750	0.84
309_I	313_F	0.750	0.84
192_G	236_A	0.750	0.84
242_I	263_T	0.748	0.84
13_I	17_V	0.745	0.84
210_G	214_G	0.745	0.84
176_L	197_A	0.744	0.84
464_T	467_G	0.743	0.84
176_L	193_A	0.742	0.84
13_I	16_R	0.742	0.84
341_M	404_G	0.741	0.84
353_L	393_P	0.740	0.84
116_K	237_W	0.740	0.84
11_N	20_P	0.739	0.84
48_K	56_V	0.738	0.84
430_V	434_L	0.733	0.83
453_L	461_I	0.731	0.83
351_L	460_F	0.731	0.83
395_V	398_C	0.730	0.83
21_G	42_L	0.730	0.83
250_M	262_I	0.728	0.83
232_V	236_A	0.728	0.83
340_S	431_A	0.726	0.83
422_S	436_T	0.725	0.82
191_N	239_C	0.725	0.82
38_H	42_L	0.724	0.82
125_I	428_G	0.723	0.82
20_P	85_E	0.721	0.82
80_S	83_L	0.719	0.82
413_W	451_G	0.719	0.82
426_P	434_L	0.719	0.82
204_N	272_Y	0.719	0.82
374_G	382_L	0.717	0.82
157_D	217_D	0.714	0.81
108_S	111_Q	0.714	0.81
303_L	310_A	0.714	0.81
423_A	434_L	0.711	0.81
346_Q	382_L	0.710	0.81
164_V	201_L	0.710	0.81
99_K	102_L	0.708	0.81
283_F	315_V	0.708	0.81
40_S	45_P	0.708	0.81
14_L	17_V	0.707	0.81
115_A	119_T	0.706	0.81
452_I	455_A	0.705	0.81
77_K	80_S	0.705	0.81
415_G	434_L	0.703	0.80
99_K	103_K	0.694	0.80
305_G	398_C	0.694	0.80
287_S	319_F	0.693	0.79
120_I	185_F	0.693	0.79
308_L	394_F	0.690	0.79
168_G	198_L	0.688	0.79
359_P	364_R	0.688	0.79
179_Y	183_Q	0.687	0.79
7_S	74_R	0.687	0.79
196_A	263_T	0.686	0.79
308_L	342_A	0.685	0.79
48_K	55_G	0.683	0.79
114_L	388_L	0.682	0.78
346_Q	374_G	0.682	0.78
170_F	173_L	0.682	0.78
138_A	166_S	0.681	0.78
29_C	32_R	0.681	0.78
399_L	402_A	0.680	0.78
142_A	159_L	0.678	0.78
413_W	447_V	0.676	0.78
134_L	261_L	0.676	0.78
346_Q	379_G	0.676	0.78
424_F	427_S	0.674	0.78
305_G	395_V	0.673	0.77
187_G	240_A	0.672	0.77
186_G	243_E	0.671	0.77
396_T	399_L	0.670	0.77
308_L	383_I	0.669	0.77
266_I	269_T	0.667	0.77
254_L	376_L	0.666	0.77
140_L	143_T	0.666	0.77
127_G	194_I	0.666	0.77
437_S	444_A	0.664	0.77
80_S	84_G	0.663	0.76
215_F	222_P	0.662	0.76
9_L	67_F	0.662	0.76
426_P	433_P	0.662	0.76
364_R	368_R	0.661	0.76
293_L	302_V	0.659	0.76
308_L	346_Q	0.658	0.76
132_G	321_P	0.658	0.76
133_L	136_G	0.657	0.76
132_G	136_G	0.657	0.76
432_L	435_M	0.655	0.76
215_F	219_F	0.653	0.75
79_M	84_G	0.652	0.75
35_L	63_V	0.651	0.75
280_G	284_E	0.651	0.75
346_Q	349_A	0.651	0.75
136_G	300_C	0.650	0.75
10_L	81_E	0.650	0.75
236_A	239_C	0.649	0.75
158_A	218_F	0.648	0.75
400_G	462_F	0.648	0.75
171_T	226_R	0.647	0.75
104_A	112_Q	0.646	0.75
301_A	304_A	0.646	0.75
27_G	61_D	0.645	0.74
366_Q	370_A	0.645	0.74
230_I	312_V	0.645	0.74
263_T	267_T	0.644	0.74
453_L	457_V	0.642	0.74
205_P	209_T	0.642	0.74
38_H	85_E	0.639	0.74
81_E	84_G	0.637	0.74
21_G	38_H	0.637	0.74
33_L	67_F	0.636	0.73
9_L	75_A	0.635	0.73
356_R	392_K	0.633	0.73
70_G	73_H	0.633	0.73
335_L	339_L	0.633	0.73
355_W	463_T	0.633	0.73
120_I	181_A	0.633	0.73
42_L	49_T	0.632	0.73
464_T	468_C	0.631	0.73
433_P	437_S	0.629	0.73
21_G	90_D	0.629	0.73
121_F	321_P	0.628	0.73
160_N	163_K	0.627	0.72
49_T	362_A	0.627	0.72
29_C	34_R	0.626	0.72
14_L	20_P	0.622	0.72
427_S	432_L	0.622	0.72
168_G	201_L	0.621	0.72
311_V	346_Q	0.621	0.72
243_E	259_T	0.621	0.72
349_A	463_T	0.620	0.72
144_V	147_V	0.620	0.72
55_G	313_F	0.620	0.72
17_V	23_I	0.618	0.71
313_F	384_Y	0.617	0.71
289_L	293_L	0.617	0.71
9_L	12_T	0.617	0.71
344_A	456_W	0.616	0.71
355_W	464_T	0.615	0.71
100_R	103_K	0.614	0.71
342_A	401_G	0.614	0.71
343_G	379_G	0.614	0.71
411_I	450_G	0.612	0.71
128_F	317_Q	0.611	0.70
447_V	454_V	0.607	0.70
135_L	201_L	0.606	0.70
157_D	160_N	0.605	0.70
10_L	83_L	0.604	0.70
225_P	276_M	0.602	0.69
283_F	296_N	0.601	0.69
367_V	371_I	0.601	0.69
40_S	43_V	0.600	0.69
235_A	267_T	0.599	0.69
371_I	374_G	0.599	0.69
158_A	219_F	0.599	0.69
344_A	452_I	0.599	0.69
11_N	78_A	0.598	0.69
187_G	263_T	0.598	0.69
270_L	274_I	0.597	0.69
243_E	247_R	0.597	0.69
342_A	397_A	0.597	0.69
235_A	270_L	0.595	0.68
345_G	400_G	0.595	0.68
341_M	455_A	0.594	0.68
318_G	321_P	0.594	0.68
305_G	308_L	0.593	0.68
16_R	43_V	0.591	0.68
400_G	403_A	0.591	0.68
389_P	393_P	0.591	0.68
343_G	397_A	0.590	0.68
311_V	342_A	0.590	0.68
238_A	241_R	0.589	0.68
11_N	23_I	0.588	0.68
288_W	292_H	0.587	0.67
284_E	329_S	0.586	0.67
80_S	87_P	0.586	0.67
428_G	434_L	0.586	0.67
424_F	431_A	0.585	0.67
256_M	259_T	0.582	0.67
104_A	107_T	0.582	0.67
403_A	406_L	0.580	0.66
407_F	410_L	0.579	0.66
27_G	65_V	0.579	0.66
349_A	396_T	0.578	0.66
101_Q	105_K	0.577	0.66
350_A	387_T	0.576	0.66
306_L	309_I	0.575	0.66
292_H	296_N	0.575	0.66
120_I	136_G	0.574	0.66
422_S	431_A	0.574	0.66
401_G	405_G	0.573	0.66
163_K	167_K	0.573	0.66
165_F	267_T	0.572	0.65
352_A	463_T	0.571	0.65
387_T	394_F	0.570	0.65
156_P	160_N	0.570	0.65
48_K	54_K	0.570	0.65
214_G	217_D	0.569	0.65
216_H	223_I	0.569	0.65
177_V	181_A	0.568	0.65
66_V	313_F	0.567	0.65
209_T	212_Y	0.566	0.65
102_L	105_K	0.566	0.65
12_T	53_V	0.565	0.64
182_A	239_C	0.565	0.64
168_G	194_I	0.565	0.64
30_M	427_S	0.563	0.64
188_T	247_R	0.563	0.64
320_I	323_Y	0.563	0.64
424_F	433_P	0.563	0.64
288_W	291_M	0.561	0.64
303_L	319_F	0.560	0.64
125_I	377_G	0.560	0.64
393_P	397_A	0.557	0.63
9_L	16_R	0.557	0.63
127_G	176_L	0.557	0.63
194_I	198_L	0.557	0.63
42_L	65_V	0.556	0.63
347_V	456_W	0.553	0.63
426_P	435_M	0.553	0.63
413_W	445_M	0.552	0.63
67_F	70_G	0.552	0.63
84_G	88_V	0.550	0.62
405_G	409_G	0.550	0.62
341_M	401_G	0.550	0.62
204_N	208_T	0.549	0.62
342_A	379_G	0.548	0.62
21_G	79_M	0.547	0.62
125_I	129_I	0.545	0.62
169_L	194_I	0.545	0.62
432_L	438_A	0.544	0.62
30_M	256_M	0.544	0.62
303_L	321_P	0.543	0.61
44_D	186_G	0.542	0.61
323_Y	333_N	0.541	0.61
350_A	354_Y	0.541	0.61
160_N	164_V	0.541	0.61
278_L	281_W	0.541	0.61
343_G	382_L	0.541	0.61
135_L	171_T	0.540	0.61
128_F	389_P	0.537	0.61
186_G	236_A	0.537	0.61
315_V	322_V	0.537	0.61
131_A	173_L	0.535	0.60
108_S	112_Q	0.535	0.60
13_I	75_A	0.534	0.60
52_G	75_A	0.532	0.60
41_S	46_N	0.531	0.60
42_L	47_I	0.530	0.60
303_L	339_L	0.529	0.59
77_K	87_P	0.528	0.59
154_T	158_A	0.526	0.59
54_K	67_F	0.525	0.59
36_G	61_D	0.524	0.59
394_F	398_C	0.523	0.59
171_T	201_L	0.522	0.58
10_L	75_A	0.522	0.58
189_G	236_A	0.522	0.58
338_I	405_G	0.520	0.58
23_I	80_S	0.520	0.58
171_T	202_G	0.518	0.58
304_A	402_A	0.518	0.58
359_P	362_A	0.517	0.58
169_L	173_L	0.517	0.58
349_A	353_L	0.517	0.58
133_L	204_N	0.514	0.57
218_F	222_P	0.513	0.57
140_L	146_H	0.512	0.57
43_V	65_V	0.510	0.57
54_K	69_P	0.510	0.57
375_L	456_W	0.509	0.57
130_A	261_L	0.509	0.57
333_N	337_P	0.508	0.56
448_Y	452_I	0.507	0.56
303_L	338_I	0.507	0.56
426_P	436_T	0.506	0.56
145_M	148_P	0.506	0.56
394_F	397_A	0.506	0.56
45_P	51_E	0.506	0.56
231_G	276_M	0.505	0.56
41_S	47_I	0.503	0.56
141_I	147_V	0.503	0.56
396_T	465_L	0.503	0.56
343_G	371_I	0.503	0.56
27_G	62_Q	0.503	0.56
347_V	371_I	0.502	0.56
353_L	390_R	0.502	0.56
308_L	398_C	0.502	0.56
428_G	438_A	0.502	0.56
27_G	30_M	0.502	0.56
353_L	387_T	0.502	0.56
148_P	155_L	0.501	0.55
290_F	322_V	0.501	0.55
367_V	370_A	0.501	0.55
178_G	186_G	0.501	0.55
206_A	209_T	0.501	0.55
181_A	239_C	0.501	0.55
86_A	457_V	0.500	0.55
434_L	437_S	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qnqA	2	0.7785	100	0.667	Contact Map
3ipjA	1	0.1983	100	0.803	Contact Map
1ibaA	1	0.1624	99.9	0.808	Contact Map
3bp3A	1	0.1688	99.9	0.809	Contact Map
2hwvA	1	0.1287	46.8	0.973	Contact Map
4n8nA	1	0.1076	46.2	0.973	Contact Map
3q9vA	1	0.1224	45.2	0.973	Contact Map
1m0sA	2	0.1603	42.5	0.974	Contact Map
4x84A	2	0.1624	42	0.974	Contact Map
2k4jA	1	0.1245	38.5	0.974	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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