GREMLIN Database
MDLA - Multidrug resistance-like ATP-binding protein MdlA
UniProt: P77265 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11622
Length: 590 (560)
Sequences: 52390 (37269)
Seq/√Len: 1574.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
336_D358_A4.3461.00
452_H462_Y4.2971.00
360_K363_Q4.1701.00
539_E551_R4.1441.00
363_Q539_E4.0931.00
339_I354_N3.9731.00
447_R452_H3.9441.00
427_A439_Q3.9251.00
424_D428_N3.8771.00
338_N392_D3.7581.00
554_H564_Y3.6501.00
334_E358_A3.6381.00
338_N394_R3.5631.00
452_H456_L3.4911.00
392_D399_P3.2421.00
427_A463_D3.0821.00
353_E547_H3.0061.00
427_A431_A2.9731.00
350_P353_E2.9721.00
439_Q443_E2.9641.00
561_S565_R2.9001.00
565_R569_R2.8531.00
438_T441_E2.8291.00
337_V340_H2.7471.00
411_R492_E2.7201.00
446_A462_Y2.7031.00
444_H448_L2.6581.00
341_Q354_N2.6541.00
336_D394_R2.6191.00
379_L495_I2.5921.00
379_L527_S2.5591.00
553_N556_V2.4711.00
541_I551_R2.4451.00
343_T350_P2.4271.00
443_E452_H2.4251.00
334_E360_K2.4111.00
550_Q560_Q2.4021.00
404_Q407_S2.3941.00
341_Q390_E2.3851.00
341_Q350_P2.3491.00
490_N522_R2.3361.00
427_A442_I2.3351.00
430_I446_A2.2761.00
359_L365_L2.2741.00
550_Q561_S2.2241.00
384_R387_D2.2101.00
544_Q563_W2.1821.00
550_Q562_G2.1571.00
44_D275_G2.1351.00
357_F541_I2.1081.00
434_C441_E2.1081.00
460_Q464_T2.1071.00
413_A491_A2.0981.00
150_I155_Q2.0901.00
364_M537_A2.0831.00
516_R536_E2.0671.00
334_E361_P2.0671.00
443_E447_R2.0381.00
451_V454_D1.9801.00
441_E490_N1.9741.00
192_A229_D1.9501.00
508_E530_R1.9401.00
443_E456_L1.9311.00
387_D401_T1.9291.00
44_D273_T1.9241.00
312_R316_A1.9221.00
552_G556_V1.9141.00
14_E91_E1.9051.00
10_Y95_D1.8991.00
343_T389_S1.8951.00
359_L525_I1.8851.00
430_I442_I1.8841.00
57_L61_A1.8481.00
337_V357_F1.8461.00
12_R15_W1.8261.00
339_I356_N1.7981.00
99_Q319_P1.7781.00
509_H513_H1.7751.00
445_V449_A1.7731.00
450_S510_Q1.7621.00
544_Q549_A1.7621.00
549_A563_W1.7541.00
157_S266_M1.7511.00
333_G396_H1.7351.00
365_L539_E1.7341.00
431_A442_I1.7211.00
439_Q463_D1.7101.00
365_L541_I1.7081.00
378_L543_M1.7021.00
364_M526_I1.6931.00
215_L218_R1.6891.00
448_L517_Q1.6881.00
363_Q538_S1.6791.00
541_I548_I1.6771.00
366_G537_A1.6741.00
444_H447_R1.6531.00
431_A439_Q1.6491.00
265_W269_Q1.6161.00
437_A488_L1.6081.00
367_I541_I1.5911.00
558_A568_Y1.5851.00
335_L525_I1.5841.00
503_V511_I1.5811.00
332_R396_H1.5801.00
123_D310_R1.5651.00
467_G472_M1.5521.00
334_E396_H1.5381.00
441_E444_H1.5381.00
102_R319_P1.5301.00
466_V473_L1.5291.00
58_M62_T1.5201.00
399_P402_K1.5111.00
199_R226_D1.5041.00
61_A65_L1.4951.00
563_W566_D1.4761.00
430_I488_L1.4721.00
453_D456_L1.4651.00
446_A455_I1.4641.00
195_S229_D1.4521.00
188_L233_K1.4361.00
460_Q465_E1.4351.00
443_E462_Y1.4341.00
370_P544_Q1.4201.00
261_G265_W1.4111.00
360_K539_E1.4091.00
367_I378_L1.4051.00
340_H388_V1.4051.00
40_G279_S1.4041.00
440_Q443_E1.4001.00
352_L355_V1.3921.00
345_P348_D1.3891.00
187_K309_S1.3891.00
383_Q414_V1.3881.00
550_Q565_R1.3801.00
337_V382_I1.3781.00
99_Q103_Q1.3651.00
535_T555_D1.3651.00
192_A233_K1.3601.00
446_A452_H1.3591.00
192_A195_S1.3581.00
423_S465_E1.3541.00
454_D477_Q1.3511.00
555_D559_Q1.3411.00
342_F381_L1.3331.00
342_F377_T1.3331.00
517_Q520_Q1.3231.00
528_A533_A1.3031.00
398_I402_K1.3011.00
341_Q353_E1.3001.00
513_H517_Q1.3001.00
331_G396_H1.2961.00
354_N547_H1.2951.00
439_Q442_I1.2871.00
181_A184_E1.2801.00
448_L487_L1.2771.00
13_R91_E1.2721.00
381_L393_I1.2671.00
441_E488_L1.2641.00
333_G361_P1.2631.00
458_L464_T1.2611.00
366_G534_L1.2591.00
342_F386_F1.2581.00
173_I177_R1.2581.00
54_G58_M1.2541.00
266_M271_S1.2491.00
24_L73_L1.2431.00
413_A486_A1.2381.00
431_A437_A1.2341.00
357_F378_L1.2261.00
203_S219_Q1.2261.00
154_T161_T1.2261.00
440_Q444_H1.2251.00
338_N356_N1.2141.00
94_E98_R1.2111.00
361_P492_E1.2071.00
519_G524_V1.2031.00
382_I525_I1.2031.00
273_T276_Q1.2031.00
36_P283_Y1.1941.00
33_L147_A1.1911.00
324_G327_P1.1911.00
370_P563_W1.1861.00
556_V560_Q1.1801.00
195_S226_D1.1781.00
350_P389_S1.1751.00
219_Q432_L1.1731.00
154_T158_W1.1701.00
454_D458_L1.1691.00
99_Q315_L1.1681.00
334_E397_D1.1621.00
365_L525_I1.1611.00
426_V481_I1.1531.00
228_E232_K1.1471.00
451_V455_I1.1451.00
111_H115_D1.1441.00
479_Q501_S1.1441.00
355_V378_L1.1351.00
323_D404_Q1.1321.00
332_R361_P1.1321.00
221_A225_A1.1311.00
211_K216_E1.1311.00
37_K41_I1.1311.00
456_L461_G1.1281.00
337_V393_I1.1271.00
467_G470_G1.1261.00
185_R236_R1.1261.00
371_T507_T1.1251.00
457_R477_Q1.1251.00
443_E446_A1.1211.00
398_I403_L1.1201.00
98_R102_R1.1161.00
388_V400_L1.1101.00
109_L386_F1.1091.00
449_A484_A1.1091.00
91_E95_D1.1051.00
446_A451_V1.1041.00
167_P255_A1.1031.00
434_C437_A1.1011.00
217_D221_A1.0981.00
364_M524_V1.0981.00
160_L280_F1.0971.00
450_S514_N1.0931.00
17_R83_G1.0921.00
453_D457_R1.0911.00
473_L481_I1.0851.00
96_Y314_M1.0841.00
445_V487_L1.0831.00
40_G44_D1.0821.00
438_T488_L1.0811.00
554_H558_A1.0801.00
206_S420_F1.0801.00
419_P482_S1.0801.00
450_S513_H1.0781.00
450_S507_T1.0771.00
561_S569_R1.0761.00
540_I554_H1.0741.00
99_Q102_R1.0721.00
115_D194_S1.0701.00
407_S410_S1.0701.00
41_I45_G1.0691.00
335_L382_I1.0681.00
337_V378_L1.0651.00
359_L523_T1.0641.00
177_R181_A1.0601.00
152_M280_F1.0601.00
405_L409_R1.0591.00
83_G87_Q1.0571.00
27_I73_L1.0531.00
199_R222_L1.0511.00
219_Q222_L1.0491.00
262_G266_M1.0431.00
112_R115_D1.0421.00
231_G235_M1.0411.00
442_I462_Y1.0401.00
9_W12_R1.0391.00
542_V563_W1.0381.00
308_Y312_R1.0351.00
526_I537_A1.0331.00
415_V486_A1.0311.00
155_Q158_W1.0281.00
343_T347_T1.0261.00
350_P390_E1.0221.00
395_F408_W1.0201.00
225_A229_D1.0171.00
344_Y351_A1.0161.00
339_I390_E1.0151.00
450_S517_Q1.0131.00
448_L518_W1.0131.00
324_G328_V1.0131.00
393_I400_L1.0121.00
264_S268_V1.0111.00
21_A81_L1.0091.00
218_R222_L1.0081.00
236_R239_R1.0071.00
381_L388_V1.0011.00
24_L76_V0.9941.00
510_Q513_H0.9941.00
492_E522_R0.9881.00
146_C150_I0.9881.00
445_V488_L0.9831.00
126_R307_A0.9811.00
90_V94_E0.9801.00
58_M61_A0.9801.00
428_N431_A0.9781.00
158_W162_L0.9771.00
506_R510_Q0.9771.00
40_G276_Q0.9741.00
188_L192_A0.9731.00
528_A534_L0.9721.00
223_F227_A0.9721.00
384_R405_L0.9661.00
107_F111_H0.9661.00
15_W19_L0.9651.00
222_L226_D0.9651.00
187_K191_A0.9641.00
109_L380_S0.9631.00
215_L219_Q0.9581.00
38_V59_W0.9571.00
494_L522_R0.9521.00
373_S543_M0.9501.00
305_S309_S0.9481.00
338_N358_A0.9451.00
486_A494_L0.9441.00
336_D397_D0.9441.00
159_Q271_S0.9431.00
427_A443_E0.9411.00
162_L166_L0.9411.00
263_G277_L0.9381.00
444_H490_N0.9361.00
224_A228_E0.9331.00
14_E87_Q0.9311.00
407_S411_R0.9311.00
229_D233_K0.9301.00
218_R221_A0.9301.00
392_D401_T0.9281.00
364_M516_R0.9241.00
556_V559_Q0.9231.00
210_I219_Q0.9211.00
354_N390_E0.9191.00
181_A240_I0.9181.00
174_M247_T0.9171.00
220_S224_A0.9131.00
442_I488_L0.9101.00
228_E231_G0.9101.00
447_R456_L0.9101.00
455_I462_Y0.9051.00
24_L80_L0.9051.00
340_H381_L0.9031.00
406_D410_S0.9031.00
185_R233_K0.9021.00
19_L23_A0.9021.00
96_Y120_A0.8981.00
363_Q551_R0.8981.00
16_R20_G0.8961.00
355_V548_I0.8941.00
366_G540_I0.8931.00
226_D229_D0.8911.00
189_A234_N0.8911.00
156_I276_Q0.8891.00
157_S161_T0.8871.00
366_G528_A0.8861.00
326_E402_K0.8861.00
498_D529_H0.8841.00
55_Q58_M0.8841.00
364_M519_G0.8831.00
343_T351_A0.8831.00
437_A441_E0.8821.00
425_T428_N0.8761.00
336_D356_N0.8741.00
172_A176_K0.8731.00
460_Q463_D0.8721.00
159_Q266_M0.8721.00
383_Q412_L0.8711.00
371_T480_R0.8711.00
104_H320_V0.8681.00
343_T348_D0.8681.00
543_M548_I0.8681.00
208_R380_S0.8671.00
548_I551_R0.8661.00
345_P349_H0.8661.00
376_S380_S0.8601.00
383_Q495_I0.8591.00
106_E110_R0.8591.00
188_L236_R0.8581.00
403_L408_W0.8571.00
466_V472_M0.8561.00
427_A462_Y0.8551.00
395_F493_I0.8541.00
95_D99_Q0.8541.00
451_V457_R0.8491.00
119_R313_A0.8491.00
163_F262_G0.8481.00
566_D569_R0.8471.00
222_L225_A0.8471.00
106_E320_V0.8451.00
562_G565_R0.8421.00
415_V483_I0.8401.00
330_E396_H0.8371.00
361_P396_H0.8371.00
176_K180_D0.8361.00
181_A185_R0.8361.00
65_L69_V0.8361.00
41_I59_W0.8341.00
388_V401_T0.8341.00
184_E188_L0.8321.00
151_M155_Q0.8281.00
456_L462_Y0.8261.00
103_Q317_E0.8261.00
266_M269_Q0.8261.00
561_S566_D0.8241.00
21_A84_A0.8241.00
233_K236_R0.8231.00
448_L452_H0.8221.00
459_P464_T0.8221.00
454_D457_R0.8211.00
394_R397_D0.8201.00
31_L73_L0.8201.00
37_K151_M0.8191.00
321_V387_D0.8191.00
221_A224_A0.8181.00
388_V393_I0.8171.00
152_M161_T0.8171.00
467_G471_V0.8161.00
217_D220_S0.8141.00
422_F429_N0.8111.00
45_G55_Q0.8111.00
544_Q547_H0.8091.00
412_L493_I0.8081.00
324_G402_K0.8081.00
448_L514_N0.8081.00
17_R87_Q0.8051.00
335_L395_F0.8041.00
330_E492_E0.8031.00
235_M239_R0.8011.00
500_L511_I0.8001.00
421_L478_K0.7931.00
149_L161_T0.7901.00
530_R533_A0.7901.00
450_S453_D0.7891.00
451_V481_I0.7891.00
37_K40_G0.7891.00
318_A322_N0.7881.00
157_S272_L0.7871.00
418_T478_K0.7861.00
491_A522_R0.7861.00
196_L230_T0.7861.00
41_I44_D0.7841.00
142_L146_C0.7831.00
126_R303_R0.7831.00
341_Q389_S0.7811.00
410_S489_V0.7811.00
421_L481_I0.7781.00
494_L519_G0.7781.00
445_V484_A0.7781.00
157_S160_L0.7761.00
31_L69_V0.7751.00
325_S328_V0.7741.00
130_A304_G0.7741.00
38_V66_I0.7731.00
209_M213_F0.7731.00
403_L407_S0.7711.00
430_I481_I0.7701.00
123_D307_A0.7691.00
458_L473_L0.7691.00
206_S209_M0.7681.00
508_E512_L0.7681.00
115_D119_R0.7681.00
560_Q565_R0.7671.00
480_R507_T0.7631.00
30_M34_V0.7611.00
311_I315_L0.7611.00
38_V62_T0.7601.00
431_A436_N0.7581.00
267_V272_L0.7561.00
327_P404_Q0.7541.00
17_R80_L0.7541.00
207_I211_K0.7521.00
96_Y311_I0.7511.00
514_N517_Q0.7491.00
430_I462_Y0.7491.00
45_G48_E0.7471.00
75_Y79_V0.7461.00
192_A226_D0.7461.00
59_W62_T0.7451.00
147_A150_I0.7441.00
159_Q162_L0.7431.00
400_L408_W0.7431.00
475_G480_R0.7411.00
25_L140_D0.7391.00
43_V278_T0.7381.00
141_S293_A0.7381.00
267_V277_L0.7381.00
232_K236_R0.7361.00
72_L76_V0.7341.00
61_A64_V0.7341.00
466_V470_G0.7331.00
483_I496_L0.7321.00
449_A480_R0.7321.00
426_V455_I0.7311.00
263_G267_V0.7301.00
229_D232_K0.7301.00
250_I254_M0.7281.00
99_Q318_A0.7271.00
560_Q563_W0.7261.00
309_S313_A0.7261.00
185_R188_L0.7251.00
434_C490_N0.7251.00
14_E17_R0.7241.00
31_L66_I0.7241.00
275_G279_S0.7241.00
444_H518_W0.7231.00
434_C489_V0.7221.00
95_D98_R0.7211.00
166_L169_P0.7191.00
188_L191_A0.7191.00
558_A565_R0.7191.00
161_T280_F0.7171.00
550_Q557_L0.7171.00
8_S12_R0.7171.00
333_G523_T0.7171.00
44_D47_T0.7171.00
368_C542_V0.7171.00
343_T349_H0.7161.00
100_L108_Y0.7161.00
431_A435_P0.7141.00
327_P407_S0.7141.00
148_V286_L0.7131.00
364_M536_E0.7111.00
62_T65_L0.7091.00
408_W412_L0.7091.00
512_L533_A0.7081.00
55_Q59_W0.7071.00
140_D144_M0.7061.00
8_S11_F0.7051.00
28_I74_R0.7041.00
154_T165_L0.7031.00
116_L314_M0.7031.00
362_G523_T0.7031.00
262_G265_W0.7031.00
353_E545_H0.7031.00
394_R399_P0.7021.00
326_E329_P0.7001.00
180_D184_E0.6991.00
344_Y377_T0.6991.00
173_I176_K0.6971.00
60_I64_V0.6971.00
349_H353_E0.6961.00
539_E553_N0.6951.00
98_R220_S0.6941.00
494_L524_V0.6931.00
95_D315_L0.6911.00
156_I279_S0.6911.00
323_D405_L0.6901.00
479_Q502_A0.6871.00
539_E556_V0.6871.00
89_A128_V0.6871.00
53_T57_L0.6861.00
554_H568_Y0.6861.00
130_A301_V0.6841.00
44_D48_E0.6821.00
475_G502_A0.6821.00
20_G80_L0.6811.00
362_G521_G0.6811.00
335_L493_I0.6801.00
347_T350_P0.6791.00
304_G307_A0.6781.00
550_Q563_W0.6781.00
266_M270_G0.6771.00
380_S386_F0.6731.00
365_L551_R0.6731.00
500_L508_E0.6711.00
431_A434_C0.6701.00
141_S145_G0.6701.00
105_P109_L0.6691.00
104_H321_V0.6681.00
69_V73_L0.6681.00
112_R198_D0.6671.00
57_L60_I0.6661.00
23_A27_I0.6661.00
326_E398_I0.6651.00
89_A93_R0.6651.00
461_G464_T0.6611.00
238_A242_A0.6581.00
37_K156_I0.6581.00
25_L77_W0.6561.00
424_D465_E0.6551.00
423_S467_G0.6541.00
441_E445_V0.6521.00
371_T498_D0.6511.00
512_L528_A0.6511.00
381_L386_F0.6501.00
151_M156_I0.6481.00
493_I523_T0.6481.00
148_V287_M0.6481.00
29_A143_V0.6471.00
513_H516_R0.6471.00
439_Q462_Y0.6461.00
321_V384_R0.6461.00
483_I511_I0.6451.00
379_L525_I0.6441.00
511_I514_N0.6441.00
16_R19_L0.6441.00
474_S477_Q0.6441.00
87_Q90_V0.6431.00
289_W293_A0.6421.00
138_L142_L0.6411.00
508_E533_A0.6391.00
563_W567_M0.6391.00
388_V392_D0.6381.00
359_L363_Q0.6361.00
555_D558_A0.6351.00
423_S472_M0.6341.00
534_L537_A0.6341.00
9_W95_D0.6341.00
54_G57_L0.6321.00
194_S310_R0.6321.00
347_T351_A0.6321.00
192_A230_T0.6321.00
564_Y567_M0.6311.00
172_A175_I0.6301.00
395_F400_L0.6281.00
425_T463_D0.6281.00
550_Q558_A0.6261.00
12_R16_R0.6261.00
236_R240_I0.6251.00
549_A561_S0.6251.00
519_G522_R0.6241.00
332_R523_T0.6231.00
331_G411_R0.6231.00
232_K235_M0.6211.00
495_I525_I0.6201.00
92_L124_V0.6181.00
103_Q319_P0.6181.00
186_F237_V0.6161.00
504_D507_T0.6141.00
355_V543_M0.6141.00
164_S284_L0.6131.00
27_I69_V0.6121.00
155_Q159_Q0.6121.00
508_E532_S0.6111.00
96_Y315_L0.6081.00
190_Q193_F0.6081.00
107_F116_L0.6051.00
367_I525_I0.6051.00
51_F55_Q0.6051.00
144_M148_V0.6051.00
418_T469_R0.6051.00
264_S267_V0.6051.00
118_A197_N0.6041.00
19_L22_V0.6041.00
119_R123_D0.6031.00
123_D190_Q0.6031.00
79_V83_G0.6031.00
177_R180_D0.6031.00
510_Q514_N0.6021.00
413_A489_V0.6021.00
328_V407_S0.6011.00
191_A195_S0.6011.00
96_Y124_V0.6011.00
129_F300_I0.6011.00
185_R237_V0.5981.00
28_I73_L0.5981.00
505_G508_E0.5971.00
272_L276_Q0.5961.00
82_F86_Y0.5961.00
125_D128_V0.5961.00
357_F548_I0.5961.00
417_Q475_G0.5951.00
328_V331_G0.5941.00
554_H557_L0.5931.00
159_Q262_G0.5931.00
148_V283_Y0.5931.00
129_F133_E0.5931.00
263_G266_M0.5921.00
450_S511_I0.5921.00
415_V496_L0.5911.00
431_A446_A0.5891.00
90_V227_A0.5891.00
379_L414_V0.5891.00
360_K365_L0.5881.00
141_S144_M0.5861.00
535_T554_H0.5851.00
189_A237_V0.5841.00
199_R219_Q0.5841.00
145_G149_L0.5831.00
340_H391_G0.5831.00
104_H107_F0.5831.00
254_M258_L0.5831.00
349_H545_H0.5821.00
352_L543_M0.5821.00
160_L266_M0.5821.00
503_V507_T0.5821.00
426_V466_V0.5821.00
99_Q317_E0.5811.00
388_V399_P0.5811.00
127_V308_Y0.5791.00
14_E88_L0.5781.00
396_H492_E0.5781.00
340_H393_I0.5781.00
62_T66_I0.5781.00
540_I553_N0.5781.00
328_V398_I0.5761.00
550_Q566_D0.5741.00
551_R556_V0.5731.00
38_V41_I0.5721.00
32_Q70_V0.5711.00
33_L36_P0.5701.00
358_A551_R0.5701.00
442_I446_A0.5701.00
272_L277_L0.5691.00
483_I487_L0.5691.00
118_A193_F0.5691.00
368_C534_L0.5671.00
449_A487_L0.5671.00
97_Y101_S0.5671.00
367_I527_S0.5661.00
446_A484_A0.5661.00
512_L526_I0.5661.00
496_L499_A0.5661.00
34_V66_I0.5661.00
199_R203_S0.5651.00
265_W268_V0.5651.00
451_V462_Y0.5651.00
342_F351_A0.5651.00
542_V550_Q0.5641.00
137_T293_A0.5641.00
170_V173_I0.5631.00
190_Q306_A0.5631.00
253_G257_L0.5621.00
169_P173_I0.5621.00
355_V541_I0.5601.00
71_Y75_Y0.5591.00
416_S419_P0.5581.00
434_C488_L0.5581.00
86_Y89_A0.5581.00
447_R453_D0.5581.00
40_G275_G0.5571.00
115_D310_R0.5571.00
140_D143_V0.5561.00
249_Y292_L0.5561.00
178_N244_F0.5561.00
429_N481_I0.5541.00
452_H455_I0.5531.00
449_A483_I0.5531.00
340_H356_N0.5521.00
380_S414_V0.5521.00
443_E455_I0.5521.00
513_H536_E0.5521.00
35_P39_V0.5511.00
114_G198_D0.5511.00
193_F197_N0.5511.00
143_V147_A0.5511.00
13_R95_D0.5501.00
337_V355_V0.5501.00
188_L229_D0.5501.00
76_V80_L0.5501.00
341_Q352_L0.5491.00
343_T390_E0.5471.00
118_A194_S0.5471.00
499_A526_I0.5471.00
92_L127_V0.5461.00
85_S132_G0.5461.00
14_E84_A0.5451.00
79_V82_F0.5441.00
68_V72_L0.5441.00
421_L466_V0.5441.00
195_S199_R0.5441.00
124_V311_I0.5431.00
512_L536_E0.5431.00
431_A488_L0.5431.00
545_H549_A0.5421.00
395_F403_L0.5421.00
242_A246_P0.5421.00
195_S198_D0.5421.00
47_T50_H0.5421.00
230_T234_N0.5411.00
29_A32_Q0.5401.00
376_S379_L0.5401.00
118_A122_N0.5401.00
525_I541_I0.5391.00
367_I543_M0.5391.00
89_A124_V0.5391.00
359_L364_M0.5381.00
405_L408_W0.5381.00
500_L503_V0.5381.00
110_R345_P0.5371.00
82_F133_E0.5361.00
507_T510_Q0.5361.00
37_K279_S0.5361.00
25_L29_A0.5351.00
27_I31_L0.5341.00
487_L518_W0.5341.00
105_P385_H0.5341.00
404_Q408_W0.5331.00
117_M121_T0.5331.00
268_V271_S0.5301.00
225_A228_E0.5291.00
331_G361_P0.5281.00
476_G504_D0.5281.00
544_Q566_D0.5271.00
322_N404_Q0.5271.00
439_Q446_A0.5271.00
360_K523_T0.5271.00
331_G395_F0.5251.00
328_V403_L0.5251.00
17_R84_A0.5251.00
480_R503_V0.5251.00
189_A193_F0.5251.00
119_R310_R0.5251.00
209_M212_A0.5241.00
113_T117_M0.5231.00
398_I407_S0.5221.00
185_R240_I0.5221.00
353_E356_N0.5221.00
13_R16_R0.5211.00
46_V55_Q0.5211.00
17_R21_A0.5191.00
28_I32_Q0.5191.00
333_G492_E0.5181.00
144_M147_A0.5181.00
350_P354_N0.5171.00
276_Q279_S0.5171.00
78_R82_F0.5171.00
446_A449_A0.5161.00
45_G49_Q0.5161.00
377_T386_F0.5151.00
34_V37_K0.5141.00
359_L541_I0.5141.00
127_V311_I0.5141.00
101_S104_H0.5131.00
57_L261_G0.5121.00
323_D327_P0.5111.00
86_Y90_V0.5111.00
59_W63_M0.5111.00
300_I303_R0.5101.00
183_H187_K0.5101.00
120_A124_V0.5101.00
505_G532_S0.5101.00
371_T503_V0.5091.00
22_V25_L0.5071.00
259_A284_L0.5071.00
526_I534_L0.5071.00
29_A33_L0.5071.00
514_N518_W0.5071.00
426_V458_L0.5061.00
210_I216_E0.5061.00
158_W161_T0.5061.00
33_L151_M0.5061.00
64_V68_V0.5061.00
558_A569_R0.5061.00
518_W522_R0.5061.00
136_L139_V0.5051.00
111_H317_E0.5041.00
535_T568_Y0.5031.00
323_D326_E0.5021.00
257_L261_G0.5021.00
165_L169_P0.5011.00
203_S210_I0.5011.00
258_L262_G0.5001.00
123_D127_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ry2A 2 0.9492 100 0.083 Contact Map
4a82A 2 0.9661 100 0.111 Contact Map
4q4hB 1 0.9661 100 0.143 Contact Map
3b5xA 2 0.9678 100 0.148 Contact Map
3b60A 2 0.9678 100 0.148 Contact Map
4f4cA 1 0.9492 100 0.149 Contact Map
4mrsA 2 0.9847 100 0.16 Contact Map
4q4hA 1 0.9644 100 0.161 Contact Map
3zdqA 2 0.9475 100 0.163 Contact Map
4q9hA 1 0.9678 100 0.166 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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