GREMLIN Database
YDJG - Uncharacterized oxidoreductase YdjG
UniProt: P77256 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13483
Length: 326 (271)
Sequences: 31681 (19661)
Seq/√Len: 1194.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
44_E299_R3.2091.00
119_A162_K2.9171.00
35_R70_Q2.8821.00
267_Y313_D2.8181.00
73_K126_G2.7821.00
310_S313_D2.4831.00
115_R156_E2.4171.00
39_I74_K2.4151.00
118_V157_L2.4121.00
5_P12_T2.3691.00
44_E48_C2.3611.00
115_R160_E2.3211.00
266_R316_L2.2121.00
155_N159_S2.1471.00
281_K314_A2.0901.00
261_Q265_A2.0381.00
129_Y164_R2.0321.00
39_I70_Q2.0281.00
206_L210_N1.9811.00
266_R313_D1.9791.00
120_A124_R1.9631.00
44_E295_P1.9611.00
295_P299_R1.9581.00
156_E160_E1.9531.00
207_C214_V1.8971.00
76_P79_Q1.8831.00
17_G52_L1.8741.00
262_P316_L1.8621.00
311_D315_T1.8561.00
111_P156_E1.8281.00
48_C299_R1.8111.00
282_Q318_R1.7101.00
134_M187_I1.6981.00
259_Q262_P1.6961.00
156_E159_S1.6861.00
269_C307_I1.6681.00
66_V124_R1.6671.00
39_I43_L1.6601.00
177_R181_Q1.6591.00
111_P115_R1.6501.00
177_R206_L1.6501.00
84_T130_I1.6421.00
86_C133_Y1.6371.00
48_C302_V1.6271.00
303_A306_N1.6251.00
270_T300_E1.6221.00
82_V127_I1.6201.00
45_A50_I1.6021.00
153_V156_E1.5941.00
84_T121_S1.5931.00
118_V133_Y1.5901.00
44_E47_R1.5891.00
277_A307_I1.5871.00
43_L74_K1.5781.00
213_V287_S1.5771.00
315_T319_E1.5741.00
34_D37_I1.5731.00
115_R119_A1.5731.00
86_C114_I1.5511.00
39_I71_A1.5311.00
20_T53_I1.5081.00
63_N66_V1.4971.00
83_E134_M1.4961.00
11_I165_A1.4911.00
35_R39_I1.4891.00
116_E120_A1.4861.00
202_E205_P1.4621.00
57_P117_E1.4361.00
172_D175_H1.4351.00
134_M215_Q1.4331.00
46_H80_V1.4191.00
37_I40_D1.4171.00
269_C273_T1.4171.00
180_L210_N1.4111.00
119_A123_Q1.4021.00
42_I71_A1.4001.00
205_P209_D1.3571.00
130_I163_I1.3491.00
208_R283_S1.3481.00
111_P152_A1.3261.00
40_D44_E1.3141.00
115_R153_V1.3131.00
299_R303_A1.3111.00
316_L319_E1.3101.00
269_C274_L1.3081.00
180_L206_L1.2981.00
11_I81_V1.2881.00
277_A281_K1.2841.00
190_A214_V1.2801.00
43_L47_R1.2791.00
173_A206_L1.2761.00
157_L163_I1.2761.00
120_A123_Q1.2761.00
259_Q316_L1.2631.00
262_P266_R1.2501.00
163_I166_I1.2381.00
125_L130_I1.2351.00
148_A182_Y1.2341.00
165_A186_D1.2321.00
111_P153_V1.2291.00
70_Q126_G1.2241.00
53_I68_V1.2191.00
69_G126_G1.2071.00
292_A297_Q1.2051.00
204_L208_R1.2031.00
81_V132_I1.1811.00
270_T273_T1.1791.00
36_Q40_D1.1761.00
66_V70_Q1.1741.00
65_E121_S1.1701.00
292_A298_V1.1701.00
261_Q271_I1.1681.00
77_R127_I1.1671.00
138_Q175_H1.1661.00
43_L75_L1.1641.00
177_R209_D1.1601.00
113_S116_E1.1351.00
263_L274_L1.1281.00
177_R210_N1.1281.00
20_T68_V1.1251.00
132_I187_I1.1211.00
296_E299_R1.1181.00
110_S113_S1.1141.00
52_L215_Q1.1131.00
112_E116_E1.1121.00
155_N158_K1.1111.00
118_V130_I1.1101.00
191_K196_D1.1081.00
279_I288_I1.1031.00
158_K186_D1.1021.00
52_L83_E1.1001.00
208_R284_D1.0931.00
192_Y282_Q1.0901.00
77_R129_Y1.0851.00
40_D295_P1.0821.00
194_I317_M1.0821.00
260_W271_I1.0811.00
119_A160_E1.0771.00
154_L166_I1.0761.00
51_N81_V1.0671.00
135_T154_L1.0591.00
195_L257_L1.0561.00
173_A177_R1.0551.00
258_E261_Q1.0541.00
9_T165_A1.0521.00
262_P265_A1.0491.00
41_T298_V1.0481.00
155_N184_E1.0371.00
258_E262_P1.0351.00
273_T303_A1.0311.00
149_E152_A1.0241.00
8_T186_D1.0211.00
109_L135_T1.0111.00
178_E182_Y1.0101.00
5_P10_D1.0061.00
157_L162_K1.0011.00
43_L71_A1.0001.00
199_M214_V0.9961.00
159_S184_E0.9951.00
72_L80_V0.9891.00
187_I215_Q0.9771.00
273_T300_E0.9761.00
148_A178_E0.9761.00
15_R280_L0.9741.00
14_S51_N0.9611.00
131_D164_R0.9591.00
280_L304_A0.9541.00
168_A185_L0.9541.00
215_Q287_S0.9521.00
201_N205_P0.9511.00
9_T186_D0.9461.00
152_A156_E0.9421.00
157_L160_E0.9331.00
70_Q74_K0.9281.00
115_R118_V0.9231.00
205_P208_R0.9231.00
14_S50_I0.9231.00
40_D43_L0.9231.00
194_I275_A0.9161.00
65_E124_R0.9111.00
300_E303_A0.9081.00
15_R305_L0.9071.00
153_V157_L0.9071.00
168_A176_I0.8981.00
294_A297_Q0.8981.00
111_P149_E0.8971.00
298_V302_V0.8971.00
281_K308_N0.8941.00
152_A155_N0.8891.00
42_I53_I0.8891.00
176_I212_I0.8881.00
115_R157_L0.8841.00
116_E119_A0.8831.00
230_T261_Q0.8771.00
312_A316_L0.8701.00
296_E300_E0.8681.00
166_I185_L0.8651.00
312_A315_T0.8631.00
46_H76_P0.8591.00
89_V108_N0.8561.00
315_T318_R0.8541.00
206_L209_D0.8531.00
208_R285_L0.8521.00
197_R200_E0.8491.00
178_E181_Q0.8491.00
57_P113_S0.8441.00
282_Q314_A0.8431.00
66_V123_Q0.8431.00
155_N183_G0.8391.00
83_E215_Q0.8361.00
18_L45_A0.8311.00
9_T158_K0.8291.00
188_I207_C0.8291.00
263_L267_Y0.8191.00
197_R318_R0.8171.00
83_E132_I0.8131.00
276_L304_A0.8091.00
35_R67_I0.8071.00
155_N166_I0.8041.00
204_L214_V0.7991.00
57_P124_R0.7891.00
266_R310_S0.7841.00
259_Q320_M0.7841.00
173_A203_L0.7801.00
267_Y310_S0.7781.00
20_T64_S0.7711.00
170_N217_Y0.7711.00
57_P120_A0.7671.00
173_A202_E0.7661.00
230_T258_E0.7651.00
275_A279_I0.7641.00
55_T68_V0.7631.00
50_I302_V0.7581.00
38_C67_I0.7561.00
46_H75_L0.7551.00
122_L162_K0.7521.00
251_L255_D0.7491.00
146_P149_E0.7481.00
281_K311_D0.7461.00
36_Q39_I0.7441.00
48_C303_A0.7421.00
44_E298_V0.7371.00
137_W170_N0.7361.00
278_W318_R0.7351.00
219_P290_S0.7341.00
192_Y204_L0.7331.00
277_A304_A0.7311.00
122_L127_I0.7301.00
108_N113_S0.7281.00
197_R201_N0.7271.00
203_L207_C0.7261.00
35_R63_N0.7251.00
309_L314_A0.7251.00
118_V162_K0.7251.00
151_V179_Y0.7231.00
117_E120_A0.7231.00
46_H53_I0.7161.00
114_I157_L0.7161.00
17_G290_S0.7131.00
16_M280_L0.7131.00
168_A171_V0.7081.00
43_L76_P0.7081.00
151_V183_G0.7041.00
269_C303_A0.7041.00
84_T133_Y0.6991.00
265_A268_Q0.6981.00
216_V219_P0.6951.00
272_P300_E0.6931.00
78_E129_Y0.6921.00
114_I150_T0.6861.00
151_V185_L0.6831.00
213_V286_I0.6821.00
293_T297_Q0.6821.00
151_V166_I0.6801.00
109_L150_T0.6801.00
263_L313_D0.6781.00
216_V288_I0.6771.00
255_D258_E0.6751.00
207_C212_I0.6721.00
192_Y279_I0.6711.00
11_I164_R0.6661.00
17_G287_S0.6621.00
204_L282_Q0.6621.00
134_M167_G0.6621.00
41_T295_P0.6591.00
175_H178_E0.6591.00
254_I258_E0.6591.00
18_L23_I0.6591.00
22_A222_Q0.6551.00
260_W275_A0.6541.00
260_W317_M0.6521.00
279_I286_I0.6501.00
154_L158_K0.6491.00
13_L287_S0.6471.00
269_C306_N0.6451.00
177_R180_L0.6451.00
145_T149_E0.6441.00
71_A75_L0.6431.00
267_Y274_L0.6421.00
121_S133_Y0.6371.00
147_I182_Y0.6371.00
274_L309_L0.6361.00
150_T153_V0.6361.00
297_Q300_E0.6351.00
37_I295_P0.6351.00
51_N79_Q0.6311.00
168_A188_I0.6301.00
58_G87_G0.6291.00
114_I153_V0.6291.00
48_C298_V0.6291.00
219_P279_I0.6271.00
46_H79_Q0.6261.00
158_K165_A0.6251.00
257_L261_Q0.6241.00
8_T211_G0.6231.00
192_Y214_V0.6211.00
274_L307_I0.6201.00
63_N67_I0.6181.00
42_I68_V0.6171.00
23_I41_T0.6161.00
313_D316_L0.6121.00
23_I38_C0.6111.00
122_L130_I0.6101.00
115_R162_K0.6101.00
42_I46_H0.6071.00
41_T292_A0.6061.00
47_R295_P0.6051.00
21_W218_S0.6041.00
76_P80_V0.6001.00
192_Y286_I0.6001.00
264_C274_L0.5981.00
86_C109_L0.5971.00
130_I133_Y0.5961.00
273_T307_I0.5941.00
269_C277_A0.5931.00
282_Q286_I0.5931.00
180_L183_G0.5901.00
147_I150_T0.5891.00
280_L288_I0.5881.00
263_L316_L0.5881.00
274_L313_D0.5861.00
274_L317_M0.5811.00
264_C267_Y0.5811.00
218_S222_Q0.5801.00
263_L320_M0.5791.00
122_L129_Y0.5781.00
158_K163_I0.5781.00
118_V122_L0.5771.00
110_S150_T0.5751.00
46_H51_N0.5751.00
54_D189_Q0.5741.00
25_G67_I0.5741.00
180_L184_E0.5711.00
255_D259_Q0.5671.00
309_L313_D0.5661.00
86_C117_E0.5661.00
179_Y185_L0.5651.00
139_S145_T0.5631.00
180_L212_I0.5611.00
168_A179_Y0.5571.00
199_M204_L0.5561.00
135_T150_T0.5561.00
195_L224_L0.5541.00
264_C271_I0.5531.00
192_Y200_E0.5511.00
216_V285_L0.5471.00
254_I257_L0.5461.00
46_H71_A0.5461.00
53_I72_L0.5461.00
13_L52_L0.5451.00
138_Q171_V0.5441.00
118_V153_V0.5441.00
158_K166_I0.5411.00
260_W264_C0.5411.00
148_A152_A0.5381.00
133_Y163_I0.5371.00
17_G289_L0.5361.00
57_P90_W0.5361.00
55_T64_S0.5351.00
24_G64_S0.5351.00
6_L213_V0.5301.00
250_M253_V0.5291.00
18_L41_T0.5291.00
277_A308_N0.5281.00
88_I109_L0.5281.00
174_D177_R0.5271.00
122_L128_D0.5261.00
216_V279_I0.5261.00
224_L257_L0.5261.00
66_V126_G0.5251.00
57_P87_G0.5241.00
139_S144_F0.5241.00
133_Y154_L0.5231.00
111_P114_I0.5191.00
190_A203_L0.5181.00
52_L81_V0.5181.00
70_Q73_K0.5171.00
192_Y197_R0.5161.00
85_K136_H0.5151.00
276_L301_N0.5141.00
147_I175_H0.5121.00
68_V71_A0.5071.00
72_L76_P0.5051.00
267_Y307_I0.5051.00
16_M305_L0.5021.00
69_G73_K0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pyfA 1 0.9479 100 0.086 Contact Map
1pz1A 1 0.954 100 0.09 Contact Map
3n2tA 1 0.9632 100 0.102 Contact Map
4xk2A 5 0.8896 100 0.105 Contact Map
3v0sA 1 0.8313 100 0.105 Contact Map
1lqaA 2 0.9632 100 0.108 Contact Map
3erpA 6 0.8834 100 0.123 Contact Map
3eauA 3 0.9356 100 0.125 Contact Map
3lutA 3 0.9325 100 0.126 Contact Map
3n6qA 5 0.8896 100 0.127 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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