GREMLIN Database
YBEQ - Uncharacterized protein YbeQ
UniProt: P77234 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13647
Length: 325 (254)
Sequences: 13374 (11915)
Seq/√Len: 747.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_D84_Q3.6911.00
295_D298_Q3.6371.00
259_D262_A3.6281.00
151_D154_L3.5991.00
223_D226_Q3.5331.00
187_N190_L3.5301.00
115_N118_E3.4141.00
45_D48_K3.2631.00
211_A231_Y2.3561.00
37_R53_L2.2881.00
139_G159_Y2.2411.00
69_G89_L2.2211.00
54_K68_L2.1421.00
53_L67_S2.1311.00
65_Q88_W2.1251.00
243_Y266_W2.1201.00
207_Q230_W2.1021.00
247_G267_F2.0881.00
174_L194_W2.0821.00
175_A195_Y2.0411.00
105_G123_Y2.0211.00
68_L88_W2.0181.00
283_A303_Y2.0121.00
138_L158_W2.0081.00
90_K104_L1.9781.00
124_Q138_L1.9461.00
123_Y137_N1.8621.00
171_Q194_W1.8341.00
246_I266_W1.8251.00
101_S122_W1.7951.00
89_L103_A1.7771.00
210_I230_W1.7451.00
279_W302_L1.7151.00
104_L122_W1.6651.00
196_L210_I1.6631.00
135_Q158_W1.6481.00
210_I214_Y1.6381.00
160_K174_L1.6321.00
195_Y209_Q1.5971.00
232_L246_I1.5951.00
68_L72_Y1.5931.00
264_F268_T1.5671.00
174_L178_Y1.5431.00
192_A196_L1.5181.00
159_Y173_N1.5061.00
268_T282_L1.4881.00
231_Y245_N1.4031.00
50_F71_K1.3911.00
178_Y190_L1.3851.00
104_L108_L1.3841.00
228_M232_L1.3831.00
246_I250_Y1.3671.00
282_L286_Y1.3621.00
50_F54_K1.3621.00
50_F72_Y1.3431.00
282_L302_L1.3391.00
72_Y84_Q1.3341.00
250_Y262_A1.3131.00
228_M249_M1.3101.00
142_Y154_L1.3021.00
72_Y88_W1.3021.00
40_A52_W1.2981.00
214_Y223_D1.2771.00
72_Y81_D1.2651.00
86_I107_T1.2551.00
267_F281_N1.2541.00
192_A213_D1.2531.00
120_V141_M1.2441.00
244_V281_N1.2351.00
117_K145_G1.2331.00
251_K267_F1.2251.00
40_A45_D1.2241.00
120_V124_Q1.2221.00
233_K236_A1.2091.00
198_S206_A1.2081.00
36_N52_W1.1991.00
156_F160_K1.1941.00
142_Y158_W1.1841.00
145_G151_D1.1831.00
37_R56_A1.1781.00
214_Y226_Q1.1771.00
108_L118_E1.1741.00
36_N40_A1.1721.00
40_A48_K1.1651.00
138_L142_Y1.1631.00
190_L193_F1.1541.00
142_Y151_D1.1491.00
203_N206_A1.1481.00
86_I90_K1.1381.00
192_A210_I1.1381.00
120_V138_L1.1351.00
47_E79_H1.1351.00
300_L304_R1.1331.00
286_Y298_Q1.1311.00
33_F52_W1.1301.00
269_K272_E1.1301.00
192_A221_D1.1251.00
120_V142_Y1.1241.00
250_Y259_D1.1181.00
228_M257_E1.1081.00
172_N209_Q1.1061.00
153_A185_A1.1051.00
162_A170_A1.1011.00
192_A214_Y1.1001.00
69_G92_A1.0981.00
197_K200_Q1.0941.00
108_L115_N1.0941.00
248_Y267_F1.0911.00
286_Y302_L1.0891.00
97_H100_A1.0881.00
208_F245_N1.0841.00
108_L122_W1.0811.00
211_A234_A1.0811.00
111_G115_N1.0751.00
161_Q164_L1.0721.00
126_A134_A1.0701.00
57_A65_Q1.0681.00
283_A306_V1.0651.00
264_F285_M1.0641.00
175_A198_S1.0621.00
156_F177_L1.0551.00
65_Q91_K1.0541.00
247_G270_A1.0471.00
139_G162_A1.0471.00
38_D67_S1.0321.00
91_K94_L1.0281.00
127_A134_A1.0281.00
270_A278_A1.0221.00
264_F282_L1.0211.00
33_F56_A1.0151.00
239_S242_A1.0151.00
50_F79_H1.0101.00
136_N173_N1.0101.00
264_F286_Y1.0081.00
50_F68_L1.0081.00
92_A100_A1.0071.00
212_W245_N1.0041.00
261_Q289_G1.0031.00
61_H64_A0.9991.00
235_A242_A0.9941.00
305_K308_S0.9931.00
178_Y187_N0.9921.00
101_S125_I0.9901.00
212_W231_Y0.9851.00
57_A64_A0.9811.00
66_Y70_Q0.9781.00
154_L157_F0.9771.00
83_E111_G0.9731.00
132_S162_A0.9711.00
135_Q162_A0.9641.00
178_Y194_W0.9631.00
207_Q234_A0.9591.00
286_Y295_D0.9471.00
93_A101_S0.9471.00
86_I111_G0.9451.00
215_N231_Y0.9441.00
289_G295_D0.9401.00
226_Q229_Y0.9401.00
41_I53_L0.9391.00
287_H303_Y0.9381.00
56_A64_A0.9381.00
275_D278_A0.9351.00
262_A265_E0.9331.00
199_A207_Q0.9301.00
101_S126_A0.9291.00
250_Y266_W0.9291.00
271_A279_W0.9271.00
156_F174_L0.9271.00
244_V248_Y0.9271.00
214_Y230_W0.9251.00
199_A206_A0.9241.00
298_Q301_D0.9231.00
125_I128_E0.9191.00
84_Q87_F0.9171.00
41_I71_K0.9161.00
225_K257_E0.9111.00
86_I104_L0.9101.00
131_M134_A0.9101.00
140_W159_Y0.9081.00
156_F185_A0.9021.00
176_D195_Y0.9011.00
118_E121_V0.8961.00
264_F289_G0.8961.00
102_N137_N0.8961.00
248_Y281_N0.8941.00
271_A278_A0.8911.00
156_F178_Y0.8881.00
235_A243_Y0.8881.00
39_S43_S0.8871.00
93_A100_A0.8861.00
171_Q198_S0.8851.00
65_Q92_A0.8831.00
167_H170_A0.8781.00
86_I108_L0.8781.00
55_L58_E0.8731.00
281_N284_I0.8721.00
280_Y284_I0.8711.00
62_C92_A0.8691.00
228_M246_I0.8681.00
135_Q161_Q0.8671.00
251_K281_N0.8631.00
73_T89_L0.8561.00
136_N170_A0.8521.00
240_V270_A0.8451.00
107_T111_G0.8411.00
46_D71_K0.8361.00
172_N206_A0.8351.00
37_R49_A0.8351.00
171_Q197_K0.8321.00
168_S198_S0.8321.00
228_M250_Y0.8291.00
179_E195_Y0.8291.00
105_G119_A0.8251.00
139_G158_W0.8181.00
70_Q103_A0.8081.00
120_V145_G0.8041.00
269_K273_C0.8031.00
82_N107_T0.7981.00
161_Q165_Q0.7981.00
260_Y285_M0.7971.00
243_Y269_K0.7961.00
66_Y103_A0.7941.00
176_D209_Q0.7931.00
52_W56_A0.7921.00
196_L226_Q0.7911.00
208_F212_W0.7901.00
194_W198_S0.7901.00
249_M257_E0.7871.00
71_K79_H0.7851.00
233_K237_Q0.7831.00
141_M145_G0.7811.00
268_T298_Q0.7781.00
247_G266_W0.7771.00
163_A171_Q0.7631.00
215_N249_M0.7621.00
245_N248_Y0.7571.00
127_A135_Q0.7541.00
204_R234_A0.7511.00
105_G126_A0.7501.00
211_A227_A0.7491.00
41_I46_D0.7481.00
92_A95_Q0.7431.00
177_L185_A0.7341.00
270_A273_C0.7321.00
73_T107_T0.7301.00
213_D221_D0.7291.00
52_W55_L0.7251.00
251_K285_M0.7251.00
109_D137_N0.7211.00
264_F295_D0.7211.00
234_A237_Q0.7191.00
175_A191_A0.7181.00
160_K190_L0.7161.00
105_G122_W0.7111.00
106_W137_N0.7081.00
69_G85_A0.7051.00
207_Q233_K0.7031.00
66_Y100_A0.7021.00
109_D141_M0.7011.00
247_G263_A0.7011.00
234_A242_A0.6981.00
135_Q165_Q0.6971.00
179_E213_D0.6961.00
189_T221_D0.6951.00
116_Y141_M0.6921.00
152_Y177_L0.6911.00
140_W173_N0.6861.00
98_T126_A0.6841.00
279_W305_K0.6801.00
158_W162_A0.6771.00
54_K84_Q0.6691.00
208_F242_A0.6661.00
139_G155_A0.6641.00
188_K192_A0.6611.00
232_L262_A0.6611.00
41_I67_S0.6611.00
38_D53_L0.6611.00
136_N140_W0.6611.00
66_Y97_H0.6591.00
248_Y251_K0.6591.00
85_A89_L0.6511.00
193_F197_K0.6511.00
64_A67_S0.6491.00
127_A138_L0.6481.00
91_K95_Q0.6471.00
143_R159_Y0.6451.00
243_Y270_A0.6441.00
232_L236_A0.6431.00
163_A174_L0.6421.00
163_A170_A0.6391.00
266_W269_K0.6381.00
106_W110_R0.6361.00
301_D305_K0.6361.00
230_W234_A0.6351.00
88_W92_A0.6311.00
121_V125_I0.6311.00
215_N252_H0.6271.00
268_T272_E0.6241.00
33_F55_L0.6231.00
34_Y38_D0.6231.00
209_Q212_W0.6221.00
173_N176_D0.6191.00
82_N86_I0.6181.00
73_T103_A0.6121.00
248_Y252_H0.6101.00
224_Y249_M0.6081.00
211_A230_W0.6071.00
70_Q74_E0.6061.00
109_D123_Y0.6051.00
196_L214_Y0.6051.00
57_A68_L0.6041.00
283_A299_A0.6041.00
48_K51_Y0.6021.00
196_L200_Q0.6021.00
260_Y289_G0.5961.00
162_A165_Q0.5951.00
122_W125_I0.5941.00
244_V278_A0.5911.00
119_A141_M0.5871.00
49_A71_K0.5851.00
160_K164_L0.5831.00
157_F161_Q0.5811.00
102_N106_W0.5751.00
49_A56_A0.5701.00
102_N134_A0.5631.00
244_V270_A0.5621.00
136_N162_A0.5601.00
131_M135_Q0.5601.00
61_H65_Q0.5591.00
49_A53_L0.5591.00
143_R152_Y0.5591.00
278_A281_N0.5581.00
230_W233_K0.5561.00
251_K288_Y0.5561.00
67_S70_Q0.5551.00
172_N203_N0.5551.00
143_R177_L0.5551.00
109_D116_Y0.5531.00
296_L300_L0.5531.00
285_M289_G0.5501.00
215_N227_A0.5501.00
267_F285_M0.5481.00
304_R308_S0.5471.00
120_V151_D0.5471.00
283_A302_L0.5461.00
62_C69_G0.5451.00
106_W123_Y0.5451.00
36_N39_S0.5441.00
93_A104_L0.5431.00
37_R41_I0.5431.00
224_Y252_H0.5421.00
164_L200_Q0.5391.00
53_L68_L0.5381.00
122_W126_A0.5371.00
86_I93_A0.5371.00
124_Q128_E0.5361.00
208_F234_A0.5351.00
51_Y55_L0.5311.00
284_I303_Y0.5281.00
66_Y92_A0.5281.00
73_T82_N0.5271.00
90_K118_E0.5261.00
179_E216_A0.5251.00
157_F160_K0.5241.00
302_L305_K0.5231.00
211_A245_N0.5231.00
37_R52_W0.5221.00
54_K58_E0.5201.00
188_K213_D0.5201.00
203_N239_S0.5151.00
229_Y233_K0.5111.00
106_W109_D0.5111.00
175_A194_W0.5101.00
279_W306_V0.5101.00
305_K309_S0.5101.00
280_Y283_A0.5091.00
137_N140_W0.5091.00
275_D279_W0.5031.00
102_N131_M0.5021.00
265_E269_K0.5021.00
70_Q89_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ouvA 1 0.7969 100 0.284 Contact Map
3e4bA 1 0.9415 100 0.297 Contact Map
4bwrA 1 0.9877 100 0.299 Contact Map
4ui9J 2 0.9169 100 0.308 Contact Map
4ui9C 2 0.9138 100 0.309 Contact Map
1w3bA 2 0.9108 100 0.314 Contact Map
4jsnB 1 0.8 100 0.326 Contact Map
2xpiA 2 0.9046 100 0.328 Contact Map
4rg9A 2 0.7508 100 0.345 Contact Map
4ui9F 2 0.9108 100 0.348 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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