GREMLIN Database
YDFJ - Putative inner membrane metabolite transport protein YdfJ
UniProt: P77228 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13822
Length: 427 (362)
Sequences: 156859 (114205)
Seq/√Len: 6002.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
80_P92_L3.9631.00
75_L96_L3.8301.00
68_M103_G3.7341.00
58_R117_E3.6131.00
77_G168_L3.3121.00
41_A98_I3.3111.00
72_C96_L3.0181.00
65_T106_A2.8731.00
49_F106_A2.8581.00
375_W378_I2.8451.00
70_G174_M2.8381.00
119_A127_I2.8101.00
91_I95_T2.7901.00
54_D343_F2.7671.00
125_G274_D2.6831.00
81_T91_I2.6731.00
72_C103_G2.5741.00
337_F345_R2.5431.00
27_A30_L2.5131.00
123_K126_I2.4651.00
223_F357_A2.4641.00
207_G211_Q2.4611.00
247_N250_I2.4611.00
81_T92_L2.4351.00
261_L316_V2.4011.00
120_P123_K2.3261.00
45_G102_L2.2941.00
227_G361_G2.2931.00
161_W165_I2.2411.00
278_R335_E2.2381.00
72_C99_I2.2021.00
288_S321_A2.1091.00
338_G341_N2.1041.00
59_K63_F2.1041.00
295_P314_L2.0901.00
53_G110_G2.0611.00
74_T171_V1.9381.00
79_L92_L1.9361.00
219_T352_I1.9241.00
265_T320_C1.9211.00
82_Y94_V1.9141.00
309_T313_A1.9111.00
179_W183_N1.8571.00
79_L96_L1.8441.00
57_G60_K1.8271.00
72_C100_Q1.7881.00
45_G105_G1.7761.00
277_G280_I1.7641.00
271_W275_K1.7511.00
376_Y379_A1.7481.00
37_A94_V1.7411.00
51_K55_R1.7221.00
76_I96_L1.7011.00
208_S211_Q1.6831.00
50_G54_D1.6791.00
37_A98_I1.6731.00
231_L365_A1.6621.00
34_T93_L1.6581.00
26_M30_L1.6581.00
41_A45_G1.6361.00
285_M324_G1.6361.00
45_G48_I1.6071.00
168_L172_V1.6051.00
379_A383_M1.6041.00
77_G171_V1.6031.00
30_L82_Y1.5731.00
26_M82_Y1.5581.00
292_L321_A1.5511.00
63_F181_R1.5391.00
178_I182_M1.5291.00
246_F250_I1.5191.00
367_I371_M1.5091.00
292_L314_L1.5071.00
70_G171_V1.4791.00
269_L324_G1.4791.00
52_M61_V1.4661.00
91_I94_V1.4661.00
126_I274_D1.4651.00
280_I283_I1.4591.00
376_Y380_I1.4541.00
205_P208_S1.4511.00
82_Y91_I1.4401.00
48_I51_K1.4391.00
385_Y389_G1.4121.00
60_K63_F1.4041.00
165_I168_L1.3861.00
162_G165_I1.3711.00
19_F22_S1.3701.00
60_K64_I1.3591.00
375_W379_A1.3471.00
309_T312_V1.3461.00
279_R283_I1.3451.00
56_I61_V1.3431.00
258_S319_N1.3391.00
241_V251_P1.3381.00
65_T103_G1.3331.00
116_A124_R1.3171.00
92_L96_L1.3151.00
144_A256_M1.3041.00
68_M72_C1.3021.00
52_M56_I1.2961.00
40_V359_G1.2941.00
270_G274_D1.2841.00
57_G61_V1.2841.00
64_I68_M1.2751.00
70_G175_V1.2741.00
230_G358_S1.2621.00
380_I384_A1.2611.00
294_W298_S1.2521.00
54_D344_T1.2501.00
261_L265_T1.2471.00
272_L276_I1.2421.00
265_T268_F1.2401.00
203_P206_A1.2391.00
204_A207_G1.2361.00
208_S341_N1.2361.00
28_L370_T1.2331.00
76_I93_L1.2321.00
53_G58_R1.2261.00
74_T78_V1.2231.00
117_E342_R1.2181.00
115_L131_V1.2171.00
377_P380_I1.2161.00
268_F271_W1.2091.00
19_F23_S1.2071.00
121_K124_R1.2051.00
239_Y244_L1.1981.00
280_I284_I1.1951.00
149_M165_I1.1931.00
21_E31_A1.1921.00
241_V248_K1.1801.00
144_A148_F1.1771.00
185_K188_P1.1691.00
75_L78_V1.1491.00
308_S312_V1.1471.00
391_I395_K1.1451.00
216_W220_G1.1421.00
384_A388_I1.1371.00
240_L246_F1.1361.00
124_R335_E1.1341.00
213_K217_L1.1321.00
56_I60_K1.1281.00
41_A101_G1.1261.00
284_I288_S1.1251.00
17_I31_A1.1211.00
250_I253_D1.1111.00
357_A361_G1.1021.00
92_L95_T1.0921.00
23_S164_R1.0891.00
267_P271_W1.0861.00
290_I294_W1.0781.00
203_P207_G1.0721.00
172_V176_F1.0681.00
71_I75_L1.0641.00
290_I386_S1.0641.00
253_D257_I1.0631.00
180_L184_L1.0491.00
262_G323_L1.0451.00
33_G363_I1.0421.00
208_S212_S1.0391.00
37_A41_A1.0371.00
69_M103_G1.0331.00
59_K186_E1.0321.00
368_F372_T1.0301.00
60_K186_E1.0291.00
126_I130_F1.0291.00
215_F219_T1.0291.00
38_G101_G1.0251.00
287_T291_V1.0211.00
292_L317_I1.0161.00
271_W274_D1.0161.00
75_L92_L1.0141.00
95_T99_I1.0101.00
78_V168_L1.0071.00
382_I386_S1.0041.00
383_M387_V1.0021.00
36_G363_I1.0021.00
341_N344_T0.9981.00
366_G370_T0.9961.00
204_A208_S0.9951.00
333_M349_S0.9911.00
38_G104_A0.9901.00
288_S292_L0.9871.00
7_S135_T0.9861.00
36_G359_G0.9841.00
380_I383_M0.9831.00
63_F67_T0.9811.00
313_A316_V0.9811.00
109_S112_G0.9791.00
32_M235_F0.9751.00
367_I370_T0.9691.00
77_G164_R0.9691.00
43_I359_G0.9641.00
58_R113_T0.9641.00
21_E28_L0.9631.00
264_M267_P0.9621.00
292_L318_H0.9581.00
61_V64_I0.9531.00
16_E150_F0.9501.00
29_I370_T0.9441.00
222_R349_S0.9421.00
297_L379_A0.9421.00
43_I351_E0.9421.00
32_M36_G0.9401.00
285_M325_L0.9401.00
239_Y243_T0.9391.00
160_A164_R0.9351.00
295_P298_S0.9321.00
264_M268_F0.9311.00
240_L311_M0.9301.00
213_K216_W0.9291.00
339_C342_R0.9181.00
33_G37_A0.9181.00
54_D58_R0.9171.00
293_A297_L0.9141.00
97_R101_G0.9081.00
313_A317_I0.9031.00
64_I67_T0.9001.00
377_P381_M0.8991.00
23_S163_W0.8981.00
50_G343_F0.8971.00
47_F51_K0.8971.00
327_A331_I0.8931.00
210_F216_W0.8911.00
290_I389_G0.8851.00
283_I286_N0.8851.00
283_I287_T0.8841.00
126_I271_W0.8841.00
147_A252_T0.8831.00
46_A350_K0.8801.00
378_I381_M0.8791.00
285_M321_A0.8741.00
202_K205_P0.8731.00
378_I382_I0.8721.00
220_G224_G0.8711.00
260_I264_M0.8691.00
80_P164_R0.8691.00
30_L94_V0.8671.00
182_M185_K0.8651.00
192_K195_D0.8551.00
276_I281_P0.8511.00
284_I287_T0.8511.00
180_L183_N0.8501.00
277_G281_P0.8461.00
171_V175_V0.8451.00
390_L394_L0.8441.00
324_G328_L0.8431.00
386_S390_L0.8401.00
145_I148_F0.8401.00
38_G42_R0.8391.00
21_E26_M0.8371.00
273_S328_L0.8341.00
74_T168_L0.8331.00
29_I33_G0.8271.00
58_R186_E0.8251.00
226_A353_G0.8211.00
179_W182_M0.8211.00
148_F160_A0.8211.00
57_G186_E0.8211.00
276_I280_I0.8201.00
347_A351_E0.8201.00
114_M184_L0.8201.00
172_V175_V0.8171.00
73_T171_V0.8171.00
119_A123_K0.8171.00
387_V391_I0.8151.00
73_T100_Q0.8131.00
299_I314_L0.8121.00
20_P163_W0.8111.00
67_T70_G0.8111.00
73_T170_S0.8071.00
249_A253_D0.8071.00
225_Q325_L0.8071.00
62_L114_M0.8071.00
30_L33_G0.8051.00
165_I169_A0.8051.00
292_L295_P0.8011.00
207_G210_F0.8001.00
45_G49_F0.7981.00
69_M174_M0.7981.00
287_T290_I0.7951.00
281_P284_I0.7941.00
202_K207_G0.7931.00
310_I313_A0.7911.00
235_F366_G0.7901.00
18_F22_S0.7881.00
222_R226_A0.7881.00
67_T71_I0.7881.00
9_G12_L0.7871.00
376_Y383_M0.7861.00
261_L264_M0.7851.00
291_V295_P0.7811.00
381_M385_Y0.7781.00
265_T269_L0.7751.00
140_L260_I0.7751.00
16_E20_P0.7751.00
141_S144_A0.7741.00
312_V316_V0.7731.00
128_S331_I0.7731.00
256_M260_I0.7721.00
116_A342_R0.7671.00
139_T259_S0.7651.00
76_I100_Q0.7651.00
217_L395_K0.7641.00
114_M118_Y0.7631.00
214_S217_L0.7621.00
65_T110_G0.7611.00
181_R185_K0.7591.00
12_L166_P0.7551.00
202_K208_S0.7541.00
168_L171_V0.7511.00
375_W389_G0.7501.00
334_A346_M0.7481.00
49_F105_G0.7441.00
122_G126_I0.7421.00
268_F272_L0.7411.00
70_G74_T0.7401.00
136_N262_G0.7361.00
116_A128_S0.7341.00
161_W164_R0.7341.00
299_I310_I0.7341.00
97_R100_Q0.7331.00
26_M31_A0.7311.00
10_A42_R0.7281.00
286_N325_L0.7281.00
379_A382_I0.7281.00
97_R108_I0.7251.00
317_I321_A0.7241.00
44_V47_F0.7201.00
150_F166_P0.7201.00
33_G94_V0.7191.00
165_I172_V0.7161.00
78_V92_L0.7161.00
240_L244_L0.7131.00
81_T164_R0.7131.00
109_S113_T0.7131.00
219_T349_S0.7101.00
34_T94_V0.7091.00
257_I312_V0.7081.00
372_T376_Y0.7081.00
51_K344_T0.7071.00
254_A312_V0.7061.00
363_I367_I0.7051.00
378_I385_Y0.7041.00
364_L367_I0.7031.00
259_S263_F0.7021.00
133_M267_P0.7001.00
136_N263_F0.7001.00
331_I335_E0.6991.00
178_I181_R0.6971.00
236_L315_I0.6951.00
378_I389_G0.6951.00
18_F21_E0.6951.00
378_I388_I0.6941.00
356_I360_F0.6901.00
76_I79_L0.6901.00
40_V43_I0.6891.00
69_M104_A0.6861.00
208_S340_K0.6861.00
219_T348_I0.6831.00
159_L249_A0.6821.00
368_F371_M0.6801.00
95_T98_I0.6781.00
38_G97_R0.6761.00
209_M212_S0.6761.00
222_R353_G0.6741.00
191_E195_D0.6721.00
301_V309_T0.6711.00
286_N389_G0.6711.00
388_I392_S0.6701.00
147_A253_D0.6701.00
143_T256_M0.6701.00
116_A334_A0.6671.00
374_S378_I0.6671.00
106_A110_G0.6671.00
16_E166_P0.6661.00
294_W297_L0.6661.00
289_A292_L0.6621.00
32_M366_G0.6621.00
289_A321_A0.6601.00
148_F253_D0.6591.00
63_F182_M0.6581.00
212_S216_W0.6571.00
115_L127_I0.6561.00
59_K185_K0.6561.00
44_V48_I0.6541.00
42_R354_G0.6541.00
246_F254_A0.6501.00
238_G242_Q0.6491.00
134_G138_G0.6471.00
169_A172_V0.6471.00
147_A256_M0.6461.00
112_G131_V0.6461.00
290_I390_L0.6461.00
314_L317_I0.6461.00
164_R168_L0.6431.00
319_N323_L0.6431.00
9_G69_M0.6411.00
375_W382_I0.6411.00
76_I167_F0.6401.00
250_I254_A0.6391.00
105_G109_S0.6381.00
295_P299_I0.6371.00
283_I290_I0.6341.00
49_F109_S0.6321.00
381_M384_A0.6321.00
35_Y234_T0.6321.00
283_I393_A0.6301.00
29_I363_I0.6301.00
196_S201_A0.6291.00
312_V315_I0.6291.00
246_F308_S0.6251.00
62_L111_A0.6251.00
215_F337_F0.6251.00
238_G241_V0.6251.00
297_L382_I0.6241.00
80_P91_I0.6231.00
216_W219_T0.6231.00
228_N385_Y0.6221.00
272_L281_P0.6201.00
30_L34_T0.6181.00
133_M136_N0.6151.00
20_P24_T0.6141.00
265_T323_L0.6141.00
392_S395_K0.6131.00
310_I314_L0.6111.00
43_I354_G0.6111.00
369_C372_T0.6111.00
27_A370_T0.6111.00
46_A347_A0.6101.00
39_Y358_S0.6101.00
133_M263_F0.6101.00
53_G61_V0.6091.00
7_S10_A0.6081.00
257_I261_L0.6061.00
214_S336_M0.6051.00
159_L162_G0.6041.00
71_I74_T0.6031.00
359_G363_I0.6011.00
212_S341_N0.6011.00
205_P209_M0.5981.00
258_S315_I0.5971.00
36_G362_P0.5961.00
391_I394_L0.5961.00
334_A342_R0.5961.00
378_I393_A0.5961.00
224_G388_I0.5961.00
15_H146_W0.5941.00
73_T97_R0.5941.00
240_L254_A0.5941.00
8_L170_S0.5931.00
219_T223_F0.5921.00
118_Y188_P0.5901.00
285_M328_L0.5881.00
69_M107_E0.5871.00
128_S334_A0.5861.00
66_I177_A0.5861.00
138_G142_A0.5831.00
250_I308_S0.5831.00
269_L272_L0.5811.00
76_I97_R0.5811.00
206_A209_M0.5811.00
34_T82_Y0.5801.00
124_R334_A0.5801.00
218_A349_S0.5801.00
235_F365_A0.5791.00
146_W166_P0.5771.00
9_G170_S0.5741.00
360_F364_L0.5741.00
53_G343_F0.5731.00
28_L242_Q0.5731.00
234_T237_A0.5721.00
8_L12_L0.5701.00
173_V176_F0.5701.00
283_I389_G0.5701.00
170_S173_V0.5671.00
220_G223_F0.5671.00
107_E181_R0.5661.00
393_A396_M0.5641.00
94_V97_R0.5641.00
46_A351_E0.5641.00
36_G40_V0.5641.00
125_G331_I0.5621.00
206_A341_N0.5621.00
249_A252_T0.5621.00
79_L82_Y0.5621.00
223_F352_I0.5601.00
50_G347_A0.5601.00
206_A344_T0.5601.00
254_A308_S0.5581.00
16_E19_F0.5571.00
39_Y362_P0.5571.00
254_A257_I0.5551.00
149_M161_W0.5541.00
49_F52_M0.5541.00
96_L99_I0.5531.00
385_Y388_I0.5531.00
142_A146_W0.5501.00
111_A131_V0.5491.00
191_E194_N0.5491.00
357_A360_F0.5491.00
143_T255_L0.5471.00
287_T389_G0.5461.00
144_A147_A0.5451.00
258_S262_G0.5431.00
348_I352_I0.5431.00
9_G97_R0.5421.00
30_L91_I0.5421.00
327_A330_N0.5411.00
46_A354_G0.5401.00
332_T336_M0.5391.00
235_F238_G0.5381.00
162_G166_P0.5341.00
294_W382_I0.5331.00
140_L256_M0.5321.00
254_A258_S0.5311.00
63_F66_I0.5291.00
132_A136_N0.5281.00
223_F227_G0.5281.00
117_E187_S0.5281.00
209_M345_R0.5261.00
125_G270_G0.5191.00
133_M137_C0.5181.00
20_P23_S0.5171.00
343_F347_A0.5161.00
126_I129_S0.5161.00
96_L100_Q0.5151.00
375_W388_I0.5141.00
112_G128_S0.5141.00
11_A139_T0.5111.00
65_T107_E0.5111.00
297_L383_M0.5101.00
369_C374_S0.5091.00
8_L142_A0.5061.00
268_F320_C0.5051.00
28_L369_C0.5051.00
389_G392_S0.5051.00
215_F345_R0.5031.00
226_A230_G0.5031.00
50_G53_G0.5021.00
272_L275_K0.5021.00
49_F61_V0.5011.00
374_S377_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4j05A 3 0.9087 100 0.181 Contact Map
4pypA 1 0.8852 100 0.191 Contact Map
3wdoA 1 0.9321 100 0.206 Contact Map
1pw4A 1 0.897 100 0.214 Contact Map
4zw9A 1 0.9297 100 0.233 Contact Map
4gc0A 1 0.9344 100 0.241 Contact Map
4ldsA 2 0.897 100 0.245 Contact Map
3o7qA 1 0.8923 100 0.249 Contact Map
2gfpA 2 0.8618 100 0.26 Contact Map
2cfqA 1 0.9251 100 0.262 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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