GREMLIN Database
YBDN - Uncharacterized protein YbdN
UniProt: P77216 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13533
Length: 406 (387)
Sequences: 232 (142)
Seq/√Len: 7.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
303_L307_E9.3271.00
78_S225_L8.5201.00
11_N14_E5.2790.99
10_L18_E4.2550.97
299_K302_H4.0840.97
193_T204_I4.0470.96
41_G75_Y3.9110.96
31_C162_M3.8150.95
25_N54_M3.7150.94
50_L54_M3.1120.86
226_C231_N3.1020.86
29_R160_A3.0030.84
26_T187_A2.8580.81
254_R281_G2.7200.78
308_Y382_S2.4450.69
218_W224_S2.3840.67
52_R85_D2.3580.66
57_K89_E2.3360.66
53_Q223_Q2.3000.64
80_R90_F2.2610.63
299_K307_E2.2170.61
294_H367_N2.1950.61
336_Q343_P2.1880.60
22_W190_K2.1780.60
123_P129_T2.1560.59
12_I19_R2.1270.58
213_A217_T2.1070.57
249_F271_M2.0880.57
229_L263_I2.0420.55
34_F236_A2.0210.54
299_K303_L1.9900.53
364_V370_Y1.9800.52
61_L256_G1.9740.52
62_F73_I1.9530.51
20_I23_T1.9370.51
385_Y396_R1.9220.50
183_K194_T1.9210.50
105_Q316_M1.8850.49
356_P362_C1.8660.48
359_R376_S1.8540.47
30_V58_I1.8140.46
316_M365_L1.7960.45
252_E308_Y1.7920.45
282_G338_K1.7500.43
278_V282_G1.7430.43
45_H219_Y1.7400.43
24_L30_V1.7400.43
161_A204_I1.7370.43
245_I276_S1.7320.43
114_E117_V1.7250.43
21_T25_N1.7170.42
43_M163_M1.7090.42
99_T142_T1.6710.40
321_A325_R1.6370.39
81_E221_N1.6180.39
70_S267_R1.6020.38
136_F153_W1.5850.37
260_Y282_G1.5770.37
81_E84_T1.5590.36
245_I374_A1.5580.36
334_W376_S1.5490.36
323_H370_Y1.5380.36
69_F292_Y1.5210.35
137_Y379_P1.5120.35
351_G354_D1.4700.33
74_N77_Q1.4670.33
154_F158_R1.4610.33
282_G294_H1.4510.33
379_P391_R1.4470.32
247_E252_E1.4440.32
144_E358_W1.4410.32
45_H83_Y1.4390.32
364_V374_A1.4220.32
123_P233_M1.4190.31
310_L358_W1.4150.31
205_Y381_K1.4130.31
166_I205_Y1.4010.31
224_S240_L1.3920.31
140_G332_L1.3920.31
246_C253_Q1.3880.30
360_R377_F1.3820.30
143_F147_V1.3790.30
366_L383_K1.3620.30
13_L160_A1.3610.30
346_Q350_I1.3480.29
196_A217_T1.3460.29
58_I149_E1.3400.29
79_L136_F1.3340.29
246_C250_G1.3310.29
21_T54_M1.3270.28
78_S116_D1.3220.28
31_C41_G1.3110.28
110_W268_W1.2950.27
57_K223_Q1.2850.27
146_F238_V1.2770.27
187_A195_A1.2730.27
101_N250_G1.2720.27
99_T354_D1.2720.27
229_L245_I1.2680.27
118_E304_D1.2650.27
264_E267_R1.2510.26
248_P268_W1.2470.26
280_S304_D1.2460.26
268_W275_V1.2330.26
259_L362_C1.2320.26
236_A259_L1.2260.25
163_M317_P1.2240.25
370_Y374_A1.2240.25
143_F376_S1.2240.25
394_G397_Q1.2220.25
30_V278_V1.2190.25
151_A207_I1.2190.25
164_I270_A1.2190.25
182_N296_K1.1990.25
164_I203_Y1.1930.24
110_W300_P1.1880.24
268_W300_P1.1860.24
302_H307_E1.1790.24
110_W275_V1.1750.24
324_Y368_N1.1650.24
271_M278_V1.1570.23
334_W370_Y1.1540.23
52_R83_Y1.1540.23
195_A239_P1.1520.23
99_T251_P1.1520.23
43_M380_T1.1480.23
143_F375_L1.1460.23
236_A362_C1.1410.23
76_V318_E1.1390.23
335_Y396_R1.1370.23
253_Q256_G1.1340.23
70_S156_Q1.1300.23
24_L120_V1.1280.23
76_V118_E1.1250.23
95_L344_Q1.1240.23
177_A243_M1.1230.22
52_R86_V1.1230.22
161_A164_I1.1200.22
231_N317_P1.1160.22
236_A317_P1.1120.22
101_N161_A1.1100.22
252_E354_D1.1100.22
331_Y376_S1.1070.22
203_Y373_R1.1070.22
48_A299_K1.1000.22
102_S151_A1.0940.22
129_T132_D1.0930.22
142_T247_E1.0900.22
30_V47_T1.0890.22
107_Q129_T1.0890.22
151_A212_V1.0870.22
65_W143_F1.0860.21
115_P130_D1.0860.21
258_W286_G1.0860.21
317_P372_C1.0850.21
70_S266_D1.0770.21
110_W248_P1.0770.21
188_D223_Q1.0770.21
218_W222_H1.0760.21
153_W192_W1.0730.21
55_G228_P1.0720.21
261_H396_R1.0710.21
362_C372_C1.0710.21
74_N336_Q1.0690.21
114_E289_N1.0640.21
11_N16_A1.0630.21
32_V198_G1.0600.21
15_A128_I1.0600.21
343_P358_W1.0530.21
128_I308_Y1.0470.20
69_F291_F1.0450.20
65_W144_E1.0440.20
286_G294_H1.0420.20
10_L239_P1.0400.20
65_W99_T1.0400.20
217_T221_N1.0390.20
71_C225_L1.0370.20
48_A86_V1.0310.20
25_N267_R1.0310.20
59_C162_M1.0300.20
134_F236_A1.0250.20
68_Q356_P1.0220.20
13_L229_L1.0210.20
166_I177_A1.0150.20
232_L347_Q1.0130.20
176_V220_A1.0110.20
282_G350_I1.0110.20
382_S391_R1.0060.19
47_T373_R1.0040.19
235_Q322_E1.0030.19
208_Y338_K1.0010.19
129_T378_S1.0000.19
30_V367_N0.9960.19
99_T247_E0.9950.19
65_W331_Y0.9940.19
379_P387_R0.9930.19
57_K283_I0.9920.19
247_E253_Q0.9900.19
344_Q358_W0.9880.19
143_F331_Y0.9870.19
110_W124_P0.9860.19
166_I203_Y0.9840.19
331_Y375_L0.9790.19
26_T188_D0.9790.19
260_Y362_C0.9770.19
379_P382_S0.9770.19
97_L112_C0.9760.19
49_E155_S0.9750.19
47_T212_V0.9720.19
338_K378_S0.9710.19
334_W375_L0.9670.19
93_V337_K0.9610.18
156_Q223_Q0.9600.18
93_V238_V0.9580.18
41_G45_H0.9480.18
144_E147_V0.9480.18
78_S219_Y0.9460.18
236_A260_Y0.9460.18
41_G225_L0.9450.18
89_E154_F0.9430.18
264_E371_W0.9370.18
254_R308_Y0.9350.18
18_E125_Q0.9330.18
112_C246_C0.9300.18
246_C376_S0.9290.18
20_I221_N0.9280.18
158_R269_A0.9230.18
157_K278_V0.9230.18
57_K319_K0.9220.18
259_L356_P0.9190.17
236_A356_P0.9130.17
164_I307_E0.9120.17
122_Q391_R0.9120.17
392_I396_R0.9100.17
275_V300_P0.9090.17
11_N18_E0.9080.17
122_Q228_P0.9060.17
200_H221_N0.9030.17
55_G223_Q0.9000.17
15_A308_Y0.8930.17
17_R21_T0.8930.17
124_P268_W0.8930.17
194_T239_P0.8900.17
172_Y271_M0.8850.17
254_R328_I0.8830.17
118_E235_Q0.8820.17
248_P300_P0.8780.17
10_L15_A0.8780.17
385_Y391_R0.8770.17
151_A162_M0.8770.17
259_L317_P0.8760.16
29_R59_C0.8740.16
11_N91_Y0.8730.16
91_Y280_S0.8720.16
168_A252_E0.8680.16
173_N205_Y0.8680.16
24_L58_I0.8680.16
151_A392_I0.8610.16
71_C78_S0.8590.16
59_C154_F0.8570.16
22_W193_T0.8540.16
163_M362_C0.8520.16
342_V346_Q0.8520.16
124_P275_V0.8510.16
161_A264_E0.8500.16
278_V293_G0.8490.16
238_V242_H0.8460.16
245_I253_Q0.8410.16
169_D383_K0.8410.16
121_R208_Y0.8400.16
75_Y235_Q0.8380.16
246_C256_G0.8360.16
77_Q92_W0.8350.16
261_H291_F0.8340.16
248_P275_V0.8340.16
176_V239_P0.8330.16
65_W252_E0.8280.15
290_H367_N0.8220.15
190_K243_M0.8200.15
75_Y79_L0.8170.15
249_F362_C0.8150.15
212_V240_L0.8130.15
95_L128_I0.8110.15
200_H379_P0.8060.15
26_T152_E0.8060.15
83_Y87_I0.8060.15
215_I272_C0.8040.15
279_K304_D0.8030.15
143_F358_W0.7990.15
347_Q365_L0.7980.15
239_P314_N0.7980.15
27_L46_L0.7940.15
147_V376_S0.7930.15
115_P293_G0.7920.15
141_M299_K0.7910.15
45_H75_Y0.7910.15
16_A53_Q0.7870.15
310_L392_I0.7870.15
122_Q298_L0.7850.15
46_L374_A0.7830.15
99_T137_Y0.7830.15
286_G378_S0.7830.15
8_L152_E0.7820.15
23_T223_Q0.7820.15
366_L372_C0.7800.15
61_L376_S0.7780.14
281_G323_H0.7770.14
155_S160_A0.7760.14
59_C150_F0.7760.14
297_I320_T0.7730.14
297_I362_C0.7720.14
41_G78_S0.7720.14
69_F162_M0.7710.14
205_Y240_L0.7690.14
14_E28_P0.7690.14
23_T228_P0.7680.14
301_E314_N0.7680.14
25_N125_Q0.7660.14
163_M372_C0.7660.14
243_M278_V0.7660.14
137_Y382_S0.7580.14
270_A386_Q0.7570.14
48_A85_D0.7570.14
29_R155_S0.7540.14
82_L120_V0.7540.14
21_T217_T0.7540.14
387_R393_K0.7530.14
92_W358_W0.7520.14
297_I366_L0.7500.14
101_N376_S0.7500.14
11_N106_Y0.7490.14
13_L17_R0.7490.14
135_C195_A0.7490.14
58_I299_K0.7490.14
360_R372_C0.7490.14
172_Y235_Q0.7460.14
348_G359_R0.7450.14
306_Q358_W0.7440.14
323_H371_W0.7410.14
134_F163_M0.7410.14
104_S107_Q0.7410.14
215_I320_T0.7400.14
140_G194_T0.7390.14
32_V163_M0.7360.14
124_P248_P0.7330.14
53_Q322_E0.7320.14
79_L264_E0.7320.14
76_V154_F0.7310.14
20_I235_Q0.7310.14
154_F382_S0.7310.14
32_V118_E0.7300.14
151_A238_V0.7300.14
148_R151_A0.7300.14
308_Y367_N0.7260.14
164_I177_A0.7260.14
112_C375_L0.7240.13
71_C211_K0.7220.13
117_V353_K0.7220.13
20_I215_I0.7210.13
306_Q310_L0.7210.13
270_A286_G0.7210.13
150_F162_M0.7210.13
52_R73_I0.7210.13
76_V86_V0.7200.13
57_K305_W0.7200.13
62_F245_I0.7190.13
261_H386_Q0.7170.13
359_R375_L0.7170.13
114_E283_I0.7140.13
188_D195_A0.7100.13
286_G289_N0.7070.13
100_Q251_P0.7060.13
245_I256_G0.7010.13
163_M337_K0.6980.13
247_E250_G0.6970.13
12_I15_A0.6960.13
155_S159_P0.6960.13
271_M362_C0.6960.13
259_L372_C0.6950.13
291_F362_C0.6920.13
37_G40_S0.6910.13
35_S40_S0.6910.13
35_S38_K0.6910.13
256_G376_S0.6900.13
210_W265_P0.6900.13
164_I355_I0.6880.13
21_T207_I0.6880.13
35_S39_D0.6850.13
368_N380_T0.6810.13
211_K395_K0.6810.13
65_W247_E0.6810.13
345_T348_G0.6770.13
52_R60_V0.6750.13
164_I205_Y0.6720.13
136_F202_W0.6710.13
68_Q347_Q0.6690.13
118_E138_Q0.6680.13
70_S118_E0.6670.12
356_P360_R0.6660.12
43_M286_G0.6630.12
243_M305_W0.6630.12
320_T326_N0.6620.12
333_H394_G0.6620.12
250_G253_Q0.6610.12
14_E81_E0.6590.12
91_Y215_I0.6590.12
161_A353_K0.6550.12
99_T252_E0.6550.12
241_R373_R0.6540.12
247_E331_Y0.6530.12
74_N122_Q0.6520.12
249_F336_Q0.6520.12
100_Q177_A0.6520.12
229_L285_A0.6520.12
118_E223_Q0.6490.12
194_T281_G0.6480.12
211_K386_Q0.6450.12
166_I178_I0.6450.12
236_A372_C0.6450.12
151_A201_S0.6430.12
78_S272_C0.6410.12
188_D200_H0.6360.12
299_K335_Y0.6360.12
118_E122_Q0.6360.12
65_W168_A0.6350.12
357_S360_R0.6350.12
356_P377_F0.6350.12
302_H306_Q0.6340.12
43_M154_F0.6340.12
55_G314_N0.6320.12
152_E395_K0.6320.12
18_E21_T0.6310.12
112_C143_F0.6300.12
128_I343_P0.6290.12
337_K392_I0.6290.12
100_Q294_H0.6290.12
126_D397_Q0.6290.12
112_C376_S0.6270.12
59_C365_L0.6270.12
78_S338_K0.6270.12
158_R202_W0.6260.12
356_P372_C0.6230.12
388_Y394_G0.6230.12
128_I358_W0.6220.12
317_P366_L0.6220.12
16_A215_I0.6210.12
102_S161_A0.6210.12
143_F256_G0.6150.12
363_K374_A0.6140.12
96_P227_N0.6120.12
169_D175_F0.6110.12
382_S385_Y0.6090.12
69_F270_A0.6090.12
169_D332_L0.6080.12
63_I334_W0.6080.12
124_P249_F0.6070.12
346_Q349_D0.6070.12
105_Q365_L0.6050.11
348_G354_D0.6050.11
5_K15_A0.6050.11
326_N380_T0.6050.11
53_Q118_E0.6040.11
172_Y378_S0.6030.11
311_L324_Y0.6010.11
338_K380_T0.5990.11
101_N309_A0.5990.11
164_I186_F0.5980.11
322_E326_N0.5960.11
14_E125_Q0.5960.11
188_D239_P0.5960.11
221_N304_D0.5940.11
5_K8_L0.5940.11
264_E296_K0.5940.11
179_A294_H0.5930.11
9_P201_S0.5910.11
130_D365_L0.5900.11
53_Q122_Q0.5880.11
23_T60_V0.5880.11
26_T199_G0.5860.11
43_M204_I0.5860.11
187_A270_A0.5850.11
251_P331_Y0.5850.11
5_K208_Y0.5830.11
308_Y322_E0.5820.11
107_Q347_Q0.5790.11
75_Y315_S0.5790.11
166_I315_S0.5770.11
353_K386_Q0.5760.11
99_T112_C0.5750.11
60_V232_L0.5720.11
135_C238_V0.5720.11
55_G152_E0.5720.11
173_N281_G0.5700.11
162_M218_W0.5700.11
124_P300_P0.5690.11
262_V393_K0.5680.11
149_E258_W0.5660.11
246_C260_Y0.5640.11
320_T387_R0.5610.11
168_A175_F0.5610.11
238_V259_L0.5590.11
154_F310_L0.5590.11
182_N397_Q0.5590.11
176_V203_Y0.5590.11
324_Y327_K0.5580.11
178_I381_K0.5560.11
94_A335_Y0.5560.11
62_F218_W0.5550.11
260_Y295_R0.5550.11
20_I273_A0.5550.11
23_T173_N0.5540.11
112_C331_Y0.5540.11
281_G358_W0.5540.11
283_I318_E0.5530.11
29_R162_M0.5520.11
48_A380_T0.5510.11
108_P250_G0.5510.11
47_T50_L0.5500.11
18_E181_L0.5490.11
213_A395_K0.5490.11
386_Q397_Q0.5470.11
52_R134_F0.5460.11
225_L264_E0.5460.11
51_A87_I0.5460.11
204_I260_Y0.5440.11
102_S392_I0.5430.11
101_N246_C0.5410.10
152_E188_D0.5410.10
260_Y268_W0.5400.10
67_A349_D0.5380.10
27_L248_P0.5370.10
227_N275_V0.5360.10
266_D333_H0.5360.10
220_A373_R0.5350.10
124_P236_A0.5340.10
378_S388_Y0.5340.10
250_G254_R0.5330.10
388_Y396_R0.5330.10
34_F249_F0.5320.10
208_Y379_P0.5320.10
146_F254_R0.5320.10
266_D343_P0.5310.10
143_F246_C0.5300.10
169_D269_A0.5300.10
337_K379_P0.5290.10
178_I213_A0.5280.10
44_L260_Y0.5270.10
11_N185_R0.5270.10
147_V375_L0.5260.10
342_V359_R0.5260.10
33_S191_P0.5240.10
47_T51_A0.5240.10
196_A203_Y0.5230.10
18_E239_P0.5230.10
231_N259_L0.5210.10
89_E157_K0.5190.10
246_C331_Y0.5190.10
364_V372_C0.5180.10
169_D343_P0.5180.10
41_G62_F0.5170.10
239_P367_N0.5170.10
139_P177_A0.5160.10
110_W260_Y0.5140.10
83_Y123_P0.5130.10
34_F260_Y0.5130.10
12_I16_A0.5120.10
34_F75_Y0.5110.10
93_V168_A0.5100.10
335_Y367_N0.5090.10
45_H217_T0.5090.10
246_C254_R0.5080.10
62_F76_V0.5050.10
350_I367_N0.5050.10
142_T354_D0.5030.10
178_I203_Y0.5020.10
347_Q356_P0.5020.10
200_H304_D0.5020.10
154_F177_A0.5020.10
185_R193_T0.5010.10
114_E118_E0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2oq2A 2 0.5911 99.9 0.879 Contact Map
4bwvA 2 0.5246 99.9 0.88 Contact Map
1zunA 1 0.4483 99.9 0.882 Contact Map
2goyA 3 0.5296 99.9 0.884 Contact Map
3fwkA 1 0.5542 99.9 0.885 Contact Map
2wsiA 1 0.5961 99.8 0.891 Contact Map
2o8vA 2 0.5197 99.8 0.893 Contact Map
1surA 2 0.4852 99.7 0.901 Contact Map
2dplA 2 0.6601 99 0.935 Contact Map
2ywbA 4 0.6773 99 0.936 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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