RCLA - ECOLI - GREMLIN Contacts

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RCLA - Probable pyridine nucleotide-disulfide oxidoreductase RclA

UniProt:	P77212	Sequences: MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCINIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFINNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGHLGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIILNAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFMTPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGASLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13580
Length:	441 (416)
Sequences:	16627 (10984)
Seq/√Len:	538.6

ECOLI - RCLA STHA DLDH GSHR HCAD NORW NIRB DHNA AHPF TRXB
BACSU - DLDH1 DLDH2 DLDH3 NASB NASD YJLD DHNA YUMB YUTJ YPDA TRXB
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27 P82854
SULSO - Q97VD9 Q97XZ3 Q97Z19 Q97WE3 Q97VQ4 Q97Y24 Q97YT2 Q97WG1 Q97U72 Q97VJ3 Q97Z14

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
162_G	243_V	4.514	1.00
277_D	281_H	3.922	1.00
34_Q	98_Q	3.537	1.00
160_H	183_K	3.412	1.00
267_A	275_V	3.033	1.00
185_T	217_I	2.976	1.00
392_A	406_V	2.926	1.00
183_K	215_D	2.764	1.00
103_N	106_S	2.739	1.00
206_A	210_R	2.667	1.00
354_D	385_K	2.605	1.00
4_Y	30_A	2.498	1.00
130_Q	257_A	2.464	1.00
107_L	111_R	2.453	1.00
354_D	384_N	2.434	1.00
383_D	386_T	2.430	1.00
132_V	253_Q	2.428	1.00
30_A	95_I	2.411	1.00
4_Y	93_D	2.370	1.00
108_R	117_E	2.365	1.00
405_I	424_F	2.364	1.00
18_L	124_F	2.355	1.00
5_Q	28_R	2.322	1.00
130_Q	255_A	2.308	1.00
137_P	224_R	2.272	1.00
387_Q	417_S	2.266	1.00
120_G	123_I	2.228	1.00
199_R	346_E	2.209	1.00
157_L	182_S	2.195	1.00
388_R	413_G	2.194	1.00
6_A	22_L	2.188	1.00
7_V	118_I	2.138	1.00
162_G	187_L	2.136	1.00
217_I	239_A	2.125	1.00
356_Q	384_N	2.112	1.00
269_N	273_A	2.088	1.00
7_V	32_I	2.084	1.00
122_K	286_N	2.055	1.00
160_H	244_D	2.045	1.00
226_S	233_Q	2.038	1.00
14_A	290_M	2.018	1.00
310_V	314_L	2.002	1.00
233_Q	240_Q	1.973	1.00
32_I	118_I	1.962	1.00
191_S	219_N	1.923	1.00
343_M	351_S	1.901	1.00
409_V	414_L	1.881	1.00
343_M	348_A	1.878	1.00
130_Q	253_Q	1.877	1.00
171_V	186_I	1.871	1.00
104_N	284_A	1.805	1.00
147_D	150_G	1.803	1.00
345_E	349_R	1.787	1.00
189_A	221_H	1.784	1.00
394_L	399_S	1.745	1.00
106_S	117_E	1.741	1.00
178_A	183_K	1.723	1.00
281_H	285_D	1.713	1.00
5_Q	121_E	1.710	1.00
7_V	120_G	1.676	1.00
161_L	182_S	1.671	1.00
35_S	38_M	1.650	1.00
288_W	313_E	1.648	1.00
355_I	381_I	1.648	1.00
380_A	392_A	1.648	1.00
107_L	286_N	1.647	1.00
346_E	350_E	1.627	1.00
145_V	225_I	1.620	1.00
124_F	314_L	1.616	1.00
267_A	283_T	1.605	1.00
28_R	93_D	1.604	1.00
161_L	177_F	1.601	1.00
231_Q	242_A	1.598	1.00
146_Y	245_A	1.579	1.00
217_I	220_A	1.571	1.00
185_T	215_D	1.564	1.00
6_A	27_W	1.512	1.00
7_V	30_A	1.511	1.00
178_A	214_V	1.507	1.00
141_T	227_H	1.506	1.00
415_P	418_I	1.500	1.00
171_V	334_M	1.499	1.00
122_K	314_L	1.493	1.00
125_I	293_V	1.486	1.00
7_V	107_L	1.485	1.00
179_N	212_Q	1.479	1.00
159_G	244_D	1.479	1.00
95_I	118_I	1.476	1.00
192_L	202_A	1.469	1.00
279_R	313_E	1.455	1.00
102_I	117_E	1.447	1.00
223_E	235_H	1.444	1.00
353_A	390_L	1.442	1.00
337_P	400_H	1.436	1.00
345_E	379_K	1.433	1.00
200_D	359_T	1.414	1.00
347_Q	350_E	1.414	1.00
278_K	322_T	1.407	1.00
30_A	118_I	1.403	1.00
21_T	312_D	1.396	1.00
127_T	293_V	1.387	1.00
101_F	123_I	1.385	1.00
204_N	395_L	1.384	1.00
208_I	211_D	1.383	1.00
100_E	110_H	1.376	1.00
280_L	294_T	1.373	1.00
95_I	116_L	1.367	1.00
106_S	119_H	1.360	1.00
84_H	96_D	1.360	1.00
124_F	290_M	1.357	1.00
220_A	237_E	1.354	1.00
348_A	355_I	1.354	1.00
6_A	124_F	1.339	1.00
100_E	108_R	1.329	1.00
281_H	286_N	1.317	1.00
159_G	183_K	1.307	1.00
146_Y	154_L	1.306	1.00
199_R	203_D	1.305	1.00
227_H	230_N	1.299	1.00
228_H	231_Q	1.295	1.00
207_T	210_R	1.292	1.00
101_F	263_N	1.283	1.00
354_D	383_D	1.281	1.00
192_L	199_R	1.279	1.00
144_G	227_H	1.264	1.00
73_E	77_F	1.264	1.00
9_I	99_A	1.262	1.00
307_Y	311_R	1.260	1.00
198_D	379_K	1.249	1.00
412_A	418_I	1.244	1.00
187_L	241_L	1.227	1.00
206_A	216_I	1.226	1.00
9_I	125_I	1.225	1.00
102_I	108_R	1.223	1.00
160_H	242_A	1.215	1.00
269_N	275_V	1.208	1.00
207_T	211_D	1.206	1.00
274_I	293_V	1.203	1.00
72_N	76_N	1.203	1.00
32_I	99_A	1.202	1.00
225_I	246_L	1.200	1.00
166_G	193_F	1.198	1.00
39_Y	94_V	1.196	1.00
135_P	139_I	1.196	1.00
224_R	235_H	1.193	1.00
284_A	287_I	1.188	1.00
226_S	235_H	1.185	1.00
164_L	246_L	1.185	1.00
348_A	381_I	1.181	1.00
84_H	88_D	1.180	1.00
51_T	54_L	1.179	1.00
50_P	54_L	1.173	1.00
25_A	312_D	1.167	1.00
345_E	357_V	1.158	1.00
151_L	177_F	1.151	1.00
188_E	218_L	1.144	1.00
111_R	116_L	1.143	1.00
357_V	381_I	1.137	1.00
133_V	147_D	1.130	1.00
269_N	295_G	1.130	1.00
264_A	284_A	1.128	1.00
4_Y	95_I	1.124	1.00
206_A	218_L	1.124	1.00
201_I	395_L	1.123	1.00
73_E	76_N	1.123	1.00
141_T	144_G	1.123	1.00
224_R	233_Q	1.121	1.00
46_I	149_T	1.120	1.00
236_S	239_A	1.118	1.00
14_A	303_S	1.114	1.00
380_A	406_V	1.112	1.00
110_H	117_E	1.101	1.00
217_I	241_L	1.100	1.00
228_H	242_A	1.096	1.00
162_G	234_V	1.093	1.00
348_A	353_A	1.088	1.00
200_D	379_K	1.087	1.00
406_V	433_L	1.084	1.00
197_E	340_R	1.078	1.00
160_H	185_T	1.076	1.00
220_A	239_A	1.069	1.00
201_I	377_V	1.064	1.00
161_L	245_A	1.062	1.00
404_N	425_T	1.061	1.00
344_T	347_Q	1.058	1.00
383_D	388_R	1.057	1.00
280_L	310_V	1.054	1.00
211_D	375_R	1.052	1.00
122_K	288_W	1.051	1.00
233_Q	242_A	1.047	1.00
50_P	53_T	1.046	1.00
228_H	233_Q	1.044	1.00
11_F	39_Y	1.040	1.00
221_H	236_S	1.038	1.00
74_V	78_L	1.038	1.00
197_E	330_Y	1.037	1.00
5_Q	30_A	1.036	1.00
414_L	418_I	1.035	1.00
339_S	403_I	1.035	1.00
290_M	310_V	1.035	1.00
362_V	396_C	1.034	1.00
378_L	432_S	1.032	1.00
193_F	206_A	1.026	1.00
192_L	206_A	1.024	1.00
261_P	266_I	1.022	1.00
359_T	377_V	1.015	1.00
56_H	60_Q	1.015	1.00
311_R	315_L	1.012	1.00
223_E	238_H	1.010	1.00
226_S	240_Q	1.008	1.00
266_I	274_I	1.002	1.00
85_N	89_M	1.002	1.00
338_L	395_L	1.001	1.00
208_I	212_Q	0.996	1.00
387_Q	416_Y	0.996	1.00
21_T	25_A	0.993	1.00
327_N	410_M	0.990	1.00
20_V	90_P	0.988	1.00
331_S	425_T	0.985	1.00
166_G	188_E	0.983	1.00
349_R	355_I	0.983	1.00
49_I	54_L	0.981	1.00
235_H	238_H	0.980	1.00
378_L	394_L	0.978	1.00
347_Q	351_S	0.975	1.00
330_Y	340_R	0.973	1.00
205_I	395_L	0.972	1.00
310_V	313_E	0.971	1.00
404_N	430_S	0.967	1.00
220_A	236_S	0.962	1.00
345_E	355_I	0.956	1.00
144_G	245_A	0.954	1.00
235_H	240_Q	0.954	1.00
35_S	46_I	0.953	1.00
164_L	248_I	0.952	1.00
356_Q	387_Q	0.952	1.00
51_T	55_V	0.951	1.00
203_D	206_A	0.950	1.00
210_R	215_D	0.946	1.00
138_G	141_T	0.945	1.00
276_V	294_T	0.944	1.00
146_Y	150_G	0.944	1.00
204_N	208_I	0.943	1.00
98_Q	258_S	0.941	1.00
51_T	58_A	0.941	1.00
8_I	19_A	0.940	1.00
186_I	216_I	0.936	1.00
353_A	383_D	0.935	1.00
205_I	338_L	0.932	1.00
93_D	116_L	0.929	1.00
268_V	275_V	0.929	1.00
312_D	317_E	0.925	1.00
193_F	218_L	0.921	1.00
32_I	95_I	0.915	1.00
31_L	87_A	0.915	1.00
136_I	139_I	0.915	1.00
164_L	250_S	0.914	1.00
25_A	315_L	0.913	1.00
359_T	379_K	0.911	1.00
175_S	179_N	0.911	1.00
22_L	311_R	0.909	1.00
223_E	236_S	0.908	1.00
76_N	81_K	0.903	1.00
11_F	31_L	0.903	1.00
171_V	209_L	0.900	1.00
105_H	286_N	0.898	1.00
398_D	401_E	0.898	1.00
160_H	243_V	0.898	1.00
162_G	241_L	0.897	1.00
231_Q	234_V	0.897	1.00
204_N	207_T	0.891	1.00
256_T	268_V	0.885	1.00
101_F	107_L	0.885	1.00
27_W	315_L	0.885	1.00
341_V	410_M	0.883	1.00
87_A	91_N	0.882	1.00
103_N	108_R	0.882	1.00
281_H	288_W	0.881	1.00
201_I	393_S	0.880	1.00
101_F	125_I	0.880	1.00
274_I	289_A	0.879	1.00
49_I	52_K	0.879	1.00
281_H	313_E	0.878	1.00
27_W	122_K	0.876	1.00
160_H	182_S	0.876	1.00
7_V	109_V	0.875	1.00
104_N	287_I	0.870	1.00
343_M	347_Q	0.869	1.00
309_I	313_E	0.868	1.00
309_I	323_D	0.865	1.00
140_T	143_P	0.859	1.00
146_Y	151_L	0.859	1.00
76_N	79_R	0.857	1.00
178_A	212_Q	0.854	1.00
405_I	408_M	0.851	1.00
389_M	406_V	0.850	1.00
27_W	121_E	0.850	1.00
132_V	250_S	0.848	1.00
279_R	318_G	0.848	1.00
164_L	222_V	0.848	1.00
289_A	293_V	0.848	1.00
254_P	273_A	0.847	1.00
150_G	153_N	0.846	1.00
185_T	243_V	0.846	1.00
266_I	283_T	0.844	1.00
276_V	289_A	0.843	1.00
5_Q	27_W	0.842	1.00
409_V	419_L	0.839	1.00
108_R	119_H	0.837	1.00
21_T	24_K	0.834	1.00
383_D	390_L	0.834	1.00
123_I	287_I	0.833	1.00
187_L	217_I	0.830	1.00
101_F	110_H	0.828	1.00
331_S	400_H	0.827	1.00
215_D	239_A	0.827	1.00
156_E	245_A	0.827	1.00
193_F	216_I	0.827	1.00
356_Q	382_V	0.826	1.00
87_A	92_I	0.826	1.00
275_V	283_T	0.826	1.00
4_Y	28_R	0.822	1.00
133_V	139_I	0.821	1.00
324_D	411_D	0.820	1.00
297_L	328_V	0.818	1.00
49_I	53_T	0.818	1.00
124_F	310_V	0.817	1.00
191_S	199_R	0.817	1.00
83_F	87_A	0.815	1.00
18_L	307_Y	0.814	1.00
56_H	59_Q	0.812	1.00
163_I	170_G	0.810	1.00
190_A	195_P	0.809	1.00
188_E	195_P	0.808	1.00
231_Q	240_Q	0.808	1.00
226_S	231_Q	0.806	1.00
266_I	284_A	0.805	1.00
187_L	220_A	0.805	1.00
209_L	214_V	0.800	1.00
145_V	248_I	0.799	1.00
134_P	248_I	0.799	1.00
22_L	27_W	0.798	1.00
17_T	304_L	0.797	1.00
208_I	375_R	0.795	1.00
104_N	107_L	0.794	1.00
72_N	75_V	0.794	1.00
97_G	112_P	0.793	1.00
7_V	123_I	0.792	1.00
52_K	55_V	0.791	1.00
278_K	321_S	0.790	1.00
143_P	227_H	0.789	1.00
27_W	314_L	0.789	1.00
192_L	346_E	0.787	1.00
282_T	289_A	0.787	1.00
339_S	399_S	0.784	1.00
18_L	311_R	0.782	1.00
174_A	186_I	0.781	1.00
264_A	287_I	0.781	1.00
281_H	284_A	0.780	1.00
161_L	247_L	0.780	1.00
411_D	421_D	0.777	1.00
104_N	286_N	0.776	1.00
30_A	93_D	0.776	1.00
158_P	182_S	0.774	1.00
353_A	381_I	0.774	1.00
54_L	58_A	0.773	1.00
57_D	70_R	0.772	1.00
32_I	111_R	0.772	1.00
208_I	395_L	0.770	1.00
101_F	120_G	0.768	1.00
170_G	188_E	0.767	1.00
345_E	381_I	0.765	1.00
203_D	207_T	0.762	1.00
75_V	78_L	0.759	1.00
23_A	92_I	0.759	1.00
82_N	86_L	0.757	1.00
18_L	310_V	0.756	1.00
50_P	56_H	0.752	1.00
349_R	352_G	0.750	1.00
86_L	90_P	0.750	1.00
261_P	268_V	0.749	1.00
70_R	73_E	0.748	1.00
4_Y	7_V	0.747	1.00
209_L	216_I	0.746	1.00
87_A	94_V	0.745	1.00
389_M	392_A	0.744	1.00
305_D	308_R	0.744	1.00
133_V	248_I	0.743	1.00
414_L	419_L	0.742	1.00
174_A	214_V	0.742	1.00
16_K	31_L	0.742	1.00
273_A	298_Q	0.741	1.00
85_N	88_D	0.741	1.00
81_K	85_N	0.740	1.00
258_S	261_P	0.740	1.00
192_L	203_D	0.738	1.00
132_V	135_P	0.735	1.00
98_Q	116_L	0.735	1.00
21_T	311_R	0.735	1.00
23_A	29_V	0.729	1.00
374_T	397_V	0.726	1.00
197_E	338_L	0.723	1.00
55_V	176_M	0.722	1.00
34_Q	255_A	0.719	1.00
408_M	414_L	0.718	1.00
358_V	382_V	0.717	1.00
361_P	364_A	0.717	1.00
45_N	79_R	0.713	1.00
20_V	24_K	0.711	1.00
49_I	58_A	0.710	1.00
6_A	311_R	0.710	1.00
276_V	280_L	0.709	1.00
113_E	116_L	0.707	1.00
388_R	415_P	0.706	1.00
257_A	262_E	0.698	1.00
341_V	407_K	0.697	1.00
163_I	247_L	0.696	1.00
41_G	97_G	0.696	1.00
392_A	410_M	0.694	1.00
51_T	56_H	0.694	1.00
280_L	313_E	0.693	1.00
302_I	328_V	0.693	1.00
9_I	259_L	0.692	1.00
261_P	264_A	0.692	1.00
198_D	393_S	0.691	1.00
136_I	140_T	0.688	1.00
189_A	195_P	0.687	1.00
74_V	77_F	0.684	1.00
137_P	141_T	0.684	1.00
43_C	48_C	0.683	1.00
136_I	222_V	0.683	1.00
416_Y	420_R	0.683	1.00
408_M	412_A	0.682	1.00
75_V	79_R	0.682	1.00
71_K	75_V	0.679	1.00
265_G	284_A	0.679	1.00
280_L	309_I	0.673	1.00
77_F	369_R	0.672	1.00
111_R	118_I	0.671	1.00
137_P	140_T	0.671	1.00
408_M	422_Q	0.669	1.00
126_N	290_M	0.669	1.00
418_I	421_D	0.667	1.00
101_F	264_A	0.667	1.00
290_M	307_Y	0.666	1.00
175_S	212_Q	0.666	1.00
5_Q	118_I	0.666	1.00
173_F	247_L	0.664	1.00
344_T	393_S	0.664	1.00
81_K	84_H	0.664	1.00
139_I	248_I	0.663	1.00
162_G	232_V	0.662	1.00
110_H	114_G	0.662	1.00
100_E	263_N	0.661	1.00
205_I	334_M	0.661	1.00
406_V	410_M	0.660	1.00
194_L	205_I	0.660	1.00
25_A	317_E	0.657	1.00
312_D	321_S	0.656	1.00
179_N	335_T	0.654	1.00
168_Y	332_V	0.653	1.00
123_I	286_N	0.653	1.00
394_L	402_M	0.652	1.00
127_T	259_L	0.652	1.00
264_A	268_V	0.652	1.00
201_I	338_L	0.652	1.00
389_M	410_M	0.652	1.00
11_F	33_E	0.648	1.00
48_C	52_K	0.646	1.00
256_T	293_V	0.645	1.00
264_A	283_T	0.645	1.00
102_I	106_S	0.645	1.00
105_H	119_H	0.642	1.00
171_V	193_F	0.641	1.00
223_E	233_Q	0.640	1.00
231_Q	235_H	0.640	1.00
408_M	419_L	0.638	1.00
139_I	145_V	0.638	1.00
51_T	173_F	0.636	1.00
58_A	179_N	0.636	1.00
22_L	314_L	0.635	1.00
361_P	377_V	0.633	1.00
382_V	416_Y	0.632	1.00
53_T	56_H	0.632	1.00
100_E	258_S	0.631	1.00
154_L	245_A	0.627	1.00
176_M	180_F	0.627	1.00
70_R	74_V	0.627	1.00
83_F	86_L	0.624	1.00
382_V	387_Q	0.621	1.00
71_K	153_N	0.620	1.00
87_A	90_P	0.619	1.00
411_D	422_Q	0.619	1.00
407_K	411_D	0.619	1.00
348_A	390_L	0.616	1.00
111_R	114_G	0.615	1.00
38_M	79_R	0.614	1.00
312_D	316_G	0.613	1.00
204_N	377_V	0.612	1.00
35_S	149_T	0.611	1.00
21_T	308_R	0.611	1.00
8_I	18_L	0.611	1.00
50_P	58_A	0.610	1.00
268_V	274_I	0.608	1.00
51_T	57_D	0.607	1.00
362_V	432_S	0.607	1.00
386_T	413_G	0.607	1.00
201_I	204_N	0.606	1.00
22_L	29_V	0.605	1.00
134_P	139_I	0.604	1.00
18_L	290_M	0.604	1.00
326_K	351_S	0.603	1.00
355_I	390_L	0.603	1.00
145_V	246_L	0.600	1.00
401_E	430_S	0.599	1.00
337_P	398_D	0.598	1.00
306_D	325_R	0.598	1.00
99_A	102_I	0.597	1.00
4_Y	122_K	0.597	1.00
135_P	140_T	0.597	1.00
33_E	38_M	0.597	1.00
38_M	46_I	0.596	1.00
273_A	295_G	0.596	1.00
141_T	150_G	0.593	1.00
381_I	384_N	0.593	1.00
262_E	268_V	0.592	1.00
23_A	91_N	0.592	1.00
86_L	89_M	0.589	1.00
305_D	309_I	0.589	1.00
177_F	182_S	0.585	0.99
8_I	29_V	0.583	0.99
392_A	403_I	0.582	0.99
72_N	153_N	0.580	0.99
308_R	312_D	0.579	0.99
14_A	126_N	0.579	0.99
343_M	353_A	0.579	0.99
168_Y	330_Y	0.577	0.99
417_S	421_D	0.575	0.99
124_F	311_R	0.575	0.99
361_P	375_R	0.574	0.99
93_D	96_D	0.574	0.99
373_D	397_V	0.573	0.99
22_L	315_L	0.573	0.99
105_H	284_A	0.572	0.99
108_R	111_R	0.572	0.99
32_I	97_G	0.568	0.99
288_W	314_L	0.567	0.99
337_P	429_M	0.567	0.99
9_I	107_L	0.564	0.99
335_T	397_V	0.563	0.99
257_A	263_N	0.563	0.99
215_D	218_L	0.562	0.99
160_H	231_Q	0.562	0.99
39_Y	84_H	0.560	0.99
302_I	306_D	0.559	0.99
71_K	74_V	0.559	0.99
160_H	178_A	0.558	0.99
193_F	202_A	0.556	0.99
6_A	314_L	0.555	0.99
242_A	245_A	0.554	0.99
346_E	349_R	0.553	0.99
392_A	433_L	0.553	0.99
366_P	370_V	0.552	0.99
279_R	322_T	0.550	0.99
294_T	306_D	0.550	0.99
49_I	55_V	0.549	0.99
234_V	241_L	0.549	0.99
149_T	252_R	0.548	0.99
197_E	332_V	0.547	0.99
41_G	152_L	0.547	0.99
270_E	275_V	0.546	0.99
133_V	138_G	0.544	0.99
170_G	189_A	0.544	0.99
426_H	431_E	0.544	0.99
182_S	244_D	0.543	0.99
54_L	57_D	0.543	0.99
129_A	252_R	0.542	0.99
212_Q	335_T	0.542	0.99
50_P	57_D	0.541	0.99
23_A	28_R	0.541	0.99
225_I	232_V	0.540	0.99
24_K	90_P	0.540	0.99
232_V	246_L	0.540	0.99
405_I	430_S	0.540	0.99
104_N	264_A	0.540	0.99
8_I	15_G	0.539	0.99
343_M	391_G	0.538	0.99
55_V	58_A	0.534	0.99
175_S	209_L	0.534	0.99
274_I	282_T	0.533	0.99
49_I	56_H	0.533	0.99
394_L	403_I	0.532	0.99
48_C	51_T	0.531	0.99
352_G	355_I	0.531	0.99
25_A	311_R	0.530	0.99
45_N	48_C	0.529	0.99
19_A	92_I	0.528	0.99
258_S	262_E	0.527	0.99
149_T	152_L	0.525	0.99
367_R	370_V	0.523	0.99
290_M	314_L	0.522	0.99
47_G	50_P	0.522	0.99
410_M	414_L	0.520	0.99
202_A	206_A	0.519	0.99
97_G	109_V	0.519	0.99
312_D	319_K	0.517	0.99
18_L	22_L	0.515	0.99
266_I	287_I	0.515	0.99
366_P	369_R	0.514	0.99
189_A	250_S	0.513	0.99
354_D	357_V	0.512	0.99
154_L	177_F	0.512	0.99
185_T	241_L	0.512	0.99
162_G	246_L	0.511	0.99
6_A	18_L	0.510	0.99
408_M	424_F	0.508	0.99
107_L	112_P	0.507	0.99
144_G	232_V	0.506	0.99
97_G	113_E	0.506	0.99
121_E	286_N	0.506	0.99
148_S	252_R	0.506	0.99
104_N	265_G	0.501	0.98
173_F	176_M	0.501	0.98
402_M	429_M	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ojtA	2	0.9864	100	0.166	Contact Map
3ladA	2	0.9909	100	0.178	Contact Map
3urhA	2	0.9796	100	0.179	Contact Map
2a8xA	2	0.9864	100	0.184	Contact Map
1zmdA	4	0.9841	100	0.188	Contact Map
1ebdA	2	0.9819	100	0.189	Contact Map
3ic9A	2	0.9841	100	0.19	Contact Map
2qaeA	2	0.9819	100	0.193	Contact Map
1xdiA	3	0.9841	100	0.193	Contact Map
1dxlA	2	0.9864	100	0.193	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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