GREMLIN Database
MNMC - tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC
UniProt: P77182 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14114
Length: 668 (630)
Sequences: 929 (664)
Seq/√Len: 26.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_L176_F6.4001.00
214_G218_R6.0881.00
525_S531_S5.2081.00
435_L457_V5.1111.00
24_F103_F5.0161.00
373_P376_L4.5241.00
268_A444_L4.4611.00
267_A288_W4.3391.00
33_N36_E3.6391.00
286_R637_E3.6311.00
292_L416_L3.6161.00
612_F615_L3.4581.00
62_V76_L3.4491.00
333_A337_Y3.4491.00
39_R119_E3.2961.00
201_A205_G3.2591.00
535_Q562_A3.2211.00
293_Y454_H3.1901.00
207_L242_G3.1731.00
81_D123_W3.1201.00
279_L612_F3.0411.00
522_H534_D3.0261.00
299_P416_L3.0181.00
461_N465_I2.9401.00
442_W609_L2.9211.00
272_G299_P2.8341.00
305_G563_R2.8211.00
480_A534_D2.7751.00
352_T385_V2.7721.00
48_L60_F2.7691.00
421_Q424_L2.7140.99
73_F97_F2.7020.99
570_T614_A2.6670.99
629_I646_L2.6350.99
266_E289_Q2.5900.99
378_V384_A2.5840.99
268_A293_Y2.5720.99
157_I188_M2.5590.99
577_V626_C2.5270.99
138_C153_W2.4650.99
46_N206_T2.4440.99
47_Q50_V2.4270.99
381_E384_A2.4250.99
288_W635_S2.4160.99
196_A199_R2.4050.99
306_N563_R2.3950.99
35_L75_T2.3820.99
629_I639_I2.3740.99
372_L376_L2.3590.98
380_V388_I2.3500.98
277_A412_T2.3400.98
307_R483_V2.2950.98
39_R78_Q2.2930.98
132_P139_H2.2450.98
432_L446_F2.2390.98
114_H128_Q2.1900.97
291_T427_Y2.1690.97
307_R485_H2.1660.97
98_I172_V2.1650.97
296_D302_G2.1540.97
629_I641_M2.1370.97
126_Q143_L2.1340.97
77_W148_V2.1330.97
380_V385_V2.1320.97
295_A431_Q2.1210.97
207_L227_M2.1210.97
284_L424_L2.1170.97
81_D144_D2.1120.97
432_L444_L2.1100.97
233_F239_M2.1060.97
465_I613_A2.0980.97
568_C614_A2.0800.97
29_F37_E2.0760.97
471_T580_V2.0610.96
351_V498_V2.0070.96
155_G160_L1.9470.95
268_A454_H1.9060.94
266_E455_S1.8890.94
174_A206_T1.8830.94
208_A239_M1.8800.94
35_L119_E1.8780.94
213_A219_G1.8730.94
279_L458_V1.8640.94
480_A564_C1.8370.93
213_A237_R1.8220.93
37_E210_F1.8100.93
286_R628_E1.7860.92
329_A333_A1.7800.92
459_L465_I1.7760.92
658_K661_K1.7730.92
438_K441_C1.7700.92
468_F471_T1.7690.92
63_A175_W1.7640.92
265_R288_W1.7570.91
73_F150_L1.7550.91
78_Q176_F1.7450.91
29_F38_T1.7400.91
349_C498_V1.7350.91
484_S535_Q1.7350.91
531_S534_D1.7150.90
35_L120_L1.7130.90
226_T245_E1.7120.90
51_R206_T1.7080.90
309_G620_L1.6820.90
140_R151_D1.6730.89
281_L285_R1.6710.89
197_M207_L1.6660.89
579_N650_N1.6580.89
530_Y560_K1.6570.89
46_N239_M1.6560.89
352_T389_T1.6460.88
324_R642_D1.6450.88
267_A456_V1.6270.88
202_R205_G1.6260.88
279_L627_A1.6240.88
389_T393_T1.6160.88
501_Y545_C1.6140.87
46_N51_R1.6070.87
276_S294_C1.5970.87
437_R441_C1.5970.87
286_R631_A1.5920.87
63_A172_V1.5870.87
180_F236_K1.5740.86
306_N519_A1.5710.86
161_T198_A1.5700.86
60_F174_A1.5680.86
312_Y500_C1.5640.86
87_H91_Q1.5600.86
521_Y617_S1.5600.86
34_G71_L1.5570.85
530_Y535_Q1.5470.85
269_I279_L1.5390.85
178_D185_N1.5340.85
324_R644_S1.5240.84
107_R111_A1.5200.84
40_Y239_M1.5130.84
352_T380_V1.4940.83
14_N31_N1.4910.83
272_G416_L1.4820.82
182_P185_N1.4820.82
284_L423_G1.4760.82
310_A498_V1.4630.82
277_A292_L1.4570.81
27_V39_R1.4400.81
175_W201_A1.4390.81
294_C426_I1.4300.80
436_S443_L1.4280.80
480_A531_S1.4280.80
399_T497_Q1.3980.79
295_A464_Q1.3960.78
215_F218_R1.3890.78
179_G185_N1.3840.78
217_R227_M1.3840.78
130_Q335_R1.3790.78
180_F185_N1.3690.77
299_P428_Y1.3620.77
390_G496_K1.3580.76
308_Q312_Y1.3560.76
185_N236_K1.3560.76
385_V388_I1.3550.76
255_P258_N1.3540.76
113_A210_F1.3490.76
69_T113_A1.3490.76
45_G230_R1.3470.76
228_Q243_V1.3440.76
268_A457_V1.3420.76
96_H151_D1.3410.76
52_F60_F1.3360.75
191_Q195_N1.3300.75
180_F189_W1.3200.74
332_F458_V1.3140.74
48_L52_F1.3140.74
69_T210_F1.3100.74
37_E69_T1.3100.74
138_C151_D1.3080.74
179_G236_K1.3000.73
521_Y569_A1.2940.73
477_Y573_H1.2910.73
269_I458_V1.2880.73
194_F219_G1.2850.72
292_L424_L1.2840.72
272_G276_S1.2770.72
334_R338_D1.2760.72
254_A257_F1.2730.72
313_P330_F1.2720.72
345_D410_E1.2700.71
284_L421_Q1.2670.71
357_D360_S1.2660.71
35_L39_R1.2610.71
444_L457_V1.2580.71
209_T229_K1.2550.71
209_T236_K1.2550.71
325_F329_A1.2520.70
45_G131_W1.2490.70
218_R222_D1.2480.70
77_W123_W1.2470.70
163_Q644_S1.2420.70
288_W455_S1.2400.70
178_D209_T1.2370.69
185_N213_A1.2370.69
100_F157_I1.2290.69
185_N209_T1.2280.69
179_G182_P1.2280.69
74_L124_A1.2240.69
569_A649_L1.2150.68
484_S539_R1.2100.68
43_L79_A1.2090.68
315_L624_P1.2070.67
188_M193_L1.2060.67
182_P232_G1.2030.67
314_L479_V1.1960.67
232_G237_R1.1880.66
506_T515_H1.1820.66
405_W500_C1.1810.66
382_A386_E1.1660.65
20_V25_D1.1660.65
459_L471_T1.1550.64
483_V563_R1.1520.64
632_A637_E1.1500.64
64_E72_N1.1480.63
207_L217_R1.1440.63
19_P34_G1.1440.63
211_T242_G1.1360.63
211_T218_R1.1270.62
326_F622_S1.1250.62
610_F634_M1.1140.61
194_F215_F1.1120.61
29_F210_F1.1110.61
500_C516_C1.1100.61
142_L332_F1.1080.61
385_V389_T1.1060.61
309_G516_C1.1040.60
380_V384_A1.1010.60
12_E22_R1.0980.60
314_L573_H1.0930.60
269_I280_S1.0930.60
495_L515_H1.0880.59
179_G189_W1.0880.59
178_D236_K1.0850.59
332_F627_A1.0800.59
593_L596_Q1.0800.59
36_E39_R1.0770.58
34_G37_E1.0730.58
126_Q129_A1.0700.58
87_H93_Q1.0700.58
626_C629_I1.0630.57
100_F160_L1.0620.57
215_F219_G1.0590.57
386_E393_T1.0590.57
330_F334_R1.0580.57
74_L127_L1.0580.57
140_R628_E1.0560.57
438_K453_T1.0530.57
386_E389_T1.0520.57
325_F622_S1.0520.57
66_G101_E1.0510.57
229_K236_K1.0510.57
185_N189_W1.0480.56
627_A631_A1.0450.56
178_D182_P1.0390.56
189_W236_K1.0350.55
121_A125_E1.0340.55
615_L626_C1.0330.55
370_M374_A1.0300.55
479_V523_R1.0280.55
499_L614_A1.0280.55
277_A416_L1.0280.55
32_D235_R1.0270.55
506_T516_C1.0260.55
81_D148_V1.0250.55
529_A533_D1.0240.55
180_F232_G1.0240.55
302_G566_V1.0220.54
308_Q500_C1.0210.54
274_I623_A1.0210.54
530_Y562_A1.0170.54
632_A640_P1.0120.54
37_E175_W1.0090.53
460_A465_I1.0070.53
590_Y650_N1.0060.53
372_L375_E1.0030.53
141_L627_A1.0000.53
309_G563_R1.0000.53
654_L657_R1.0000.53
274_I293_Y0.9990.53
153_W160_L0.9960.53
29_F69_T0.9950.52
425_Q540_Q0.9940.52
475_P654_L0.9930.52
191_Q222_D0.9920.52
232_G236_K0.9910.52
124_A128_Q0.9890.52
282_A534_D0.9850.52
570_T610_F0.9850.52
185_N237_R0.9820.51
213_A233_F0.9820.51
432_L452_A0.9810.51
284_L422_Q0.9790.51
520_S534_D0.9760.51
277_A415_V0.9750.51
268_A455_S0.9750.51
229_K237_R0.9730.51
516_C519_A0.9720.51
319_D324_R0.9690.50
293_Y432_L0.9690.50
213_A236_K0.9680.50
109_D112_L0.9680.50
185_N232_G0.9670.50
132_P141_L0.9640.50
50_V270_I0.9630.50
99_S150_L0.9630.50
26_D236_K0.9610.50
464_Q467_R0.9610.50
311_L621_C0.9600.50
102_K330_F0.9590.50
487_P556_D0.9590.50
38_T75_T0.9580.50
190_T197_M0.9580.50
40_Y45_G0.9560.50
292_L426_I0.9550.49
180_F209_T0.9540.49
639_I646_L0.9530.49
99_S152_L0.9530.49
189_W209_T0.9520.49
50_V448_G0.9520.49
212_S227_M0.9520.49
34_G210_F0.9490.49
306_N309_G0.9480.49
469_S472_S0.9470.49
178_D213_A0.9450.49
47_Q230_R0.9450.49
297_E429_Q0.9450.49
130_Q143_L0.9440.49
62_V614_A0.9420.48
209_T216_V0.9360.48
78_Q82_Q0.9340.48
179_G209_T0.9320.48
614_A626_C0.9320.48
182_P213_A0.9310.48
294_C298_A0.9280.47
306_N538_N0.9270.47
385_V393_T0.9260.47
52_F335_R0.9260.47
440_D457_V0.9240.47
487_P559_D0.9240.47
589_E601_V0.9230.47
64_E185_N0.9220.47
126_Q144_D0.9220.47
231_K238_E0.9200.47
213_A216_V0.9190.47
184_K216_V0.9120.46
535_Q559_D0.9100.46
185_N229_K0.9060.46
182_P236_K0.9030.46
308_Q405_W0.8990.45
14_N20_V0.8950.45
52_F80_F0.8940.45
178_D189_W0.8930.45
492_L515_H0.8930.45
526_E566_V0.8920.45
211_T216_V0.8910.45
77_W81_D0.8890.45
46_N242_G0.8870.44
312_Y351_V0.8810.44
218_R238_E0.8800.44
272_G294_C0.8750.44
309_G519_A0.8730.43
212_S240_L0.8720.43
572_D653_R0.8710.43
130_Q141_L0.8660.43
365_A458_V0.8650.43
131_W396_S0.8640.43
528_T564_C0.8600.42
172_V200_L0.8580.42
270_I444_L0.8560.42
479_V573_H0.8540.42
483_V506_T0.8540.42
210_F312_Y0.8500.42
579_N608_D0.8500.42
519_A538_N0.8480.42
642_D645_T0.8470.41
280_S292_L0.8460.41
316_S363_K0.8460.41
49_E76_L0.8440.41
336_F340_L0.8440.41
162_S627_A0.8430.41
481_G565_G0.8400.41
185_N210_F0.8400.41
94_R637_E0.8390.41
26_D185_N0.8370.41
36_E44_G0.8360.41
26_D182_P0.8310.40
571_R655_W0.8300.40
309_G474_L0.8300.40
329_A612_F0.8300.40
267_A635_S0.8290.40
26_D213_A0.8290.40
266_E291_T0.8290.40
615_L622_S0.8270.40
282_A628_E0.8250.40
306_N572_D0.8220.40
345_D509_N0.8200.40
35_L77_W0.8200.40
143_L154_F0.8190.39
389_T497_Q0.8170.39
131_W205_G0.8170.39
43_L49_E0.8160.39
633_Q646_L0.8160.39
50_V54_E0.8160.39
22_R190_T0.8140.39
190_T193_L0.8120.39
456_V608_D0.8110.39
577_V629_I0.8090.39
480_A525_S0.8080.39
125_E129_A0.8080.39
207_L617_S0.8060.39
103_F187_D0.8060.39
231_K241_C0.8050.38
106_T109_D0.8050.38
66_G232_G0.8050.38
108_A111_A0.8050.38
200_L625_L0.8040.38
64_E236_K0.8020.38
64_E180_F0.7980.38
437_R607_D0.7970.38
278_L336_F0.7970.38
131_W319_D0.7960.38
126_Q146_G0.7950.38
144_D148_V0.7940.38
24_F187_D0.7930.38
189_W232_G0.7930.38
303_A462_G0.7930.38
443_L453_T0.7900.37
64_E101_E0.7890.37
182_P237_R0.7890.37
577_V649_L0.7870.37
540_Q543_I0.7870.37
179_G232_G0.7870.37
480_A522_H0.7860.37
210_F236_K0.7860.37
161_T618_R0.7860.37
48_L381_E0.7860.37
264_K288_W0.7850.37
522_H531_S0.7850.37
38_T210_F0.7840.37
312_Y507_P0.7840.37
26_D178_D0.7840.37
199_R403_G0.7840.37
380_V527_D0.7810.37
577_V612_F0.7800.37
26_D180_F0.7780.37
573_H618_R0.7760.36
577_V630_L0.7750.36
87_H92_L0.7720.36
314_L360_S0.7700.36
67_F73_F0.7690.36
197_M223_A0.7670.36
97_F209_T0.7670.36
60_F239_M0.7670.36
284_L292_L0.7670.36
618_R657_R0.7650.36
25_D145_E0.7610.35
312_Y573_H0.7590.35
100_F153_W0.7590.35
196_A200_L0.7580.35
269_I646_L0.7580.35
265_R635_S0.7580.35
456_V610_F0.7580.35
275_A382_A0.7570.35
10_N23_D0.7570.35
214_G217_R0.7550.35
33_N37_E0.7540.35
521_Y571_R0.7520.35
522_H566_V0.7510.35
286_R635_S0.7500.35
120_L214_G0.7500.35
66_G185_N0.7500.35
66_G72_N0.7480.35
282_A640_P0.7470.34
12_E23_D0.7460.34
51_R174_A0.7460.34
77_W146_G0.7460.34
137_G637_E0.7460.34
190_T194_F0.7460.34
312_Y624_P0.7420.34
179_G188_M0.7400.34
256_W259_R0.7390.34
210_F213_A0.7390.34
272_G426_I0.7390.34
313_P573_H0.7380.34
267_A454_H0.7370.34
628_E631_A0.7370.34
145_E458_V0.7370.34
27_V30_S0.7370.34
149_T610_F0.7360.34
182_P189_W0.7350.34
274_I620_L0.7340.34
580_V609_L0.7340.34
488_T492_L0.7330.34
189_W216_V0.7330.34
124_A380_V0.7320.33
353_Q400_Y0.7320.33
484_S519_A0.7310.33
211_T237_R0.7300.33
326_F573_H0.7290.33
14_N18_T0.7290.33
217_R221_Q0.7280.33
596_Q599_E0.7270.33
64_E209_T0.7270.33
102_K239_M0.7270.33
618_R625_L0.7270.33
50_V53_P0.7260.33
103_F210_F0.7250.33
63_A212_S0.7250.33
370_M376_L0.7250.33
180_F211_T0.7240.33
293_Y430_Y0.7240.33
157_I196_A0.7230.33
393_T396_S0.7230.33
337_Y406_L0.7230.33
76_L97_F0.7230.33
81_D87_H0.7220.33
589_E604_P0.7190.33
140_R286_R0.7180.33
270_I457_V0.7180.33
332_F461_N0.7170.32
34_G117_W0.7160.32
28_Y180_F0.7150.32
643_A647_A0.7140.32
380_V389_T0.7130.32
11_L21_S0.7120.32
134_P139_H0.7110.32
430_Y446_F0.7100.32
269_I284_L0.7100.32
590_Y593_L0.7090.32
57_H202_R0.7080.32
72_N232_G0.7080.32
39_R75_T0.7070.32
462_G621_C0.7070.32
501_Y617_S0.7060.32
594_A659_L0.7060.32
217_R232_G0.7050.32
401_P495_L0.7040.32
34_G69_T0.7040.32
355_G361_Q0.7030.32
209_T213_A0.7020.32
389_T495_L0.7010.31
628_E637_E0.7000.31
201_A241_C0.6990.31
178_D188_M0.6990.31
432_L461_N0.6990.31
546_F639_I0.6990.31
40_Y231_K0.6980.31
182_P229_K0.6980.31
268_A456_V0.6970.31
52_F57_H0.6970.31
77_W144_D0.6960.31
185_N188_M0.6940.31
268_A274_I0.6940.31
523_R573_H0.6900.31
50_V439_D0.6890.31
193_L210_F0.6880.31
47_Q243_V0.6880.31
574_L648_A0.6870.31
407_C617_S0.6870.31
326_F618_R0.6870.31
270_I459_L0.6860.30
329_A337_Y0.6860.30
155_G159_E0.6850.30
293_Y452_A0.6850.30
213_A234_G0.6850.30
489_T515_H0.6850.30
571_R654_L0.6840.30
312_Y405_W0.6840.30
349_C500_C0.6820.30
576_M650_N0.6820.30
436_S445_N0.6810.30
73_F148_V0.6810.30
140_R149_T0.6810.30
98_I577_V0.6780.30
132_P154_F0.6770.30
277_A377_A0.6770.30
505_L515_H0.6760.30
178_D237_R0.6760.30
138_C642_D0.6750.30
309_G565_G0.6750.30
435_L570_T0.6750.30
610_F631_A0.6750.30
154_F309_G0.6740.30
325_F649_L0.6730.30
179_G229_K0.6710.30
260_T536_Q0.6710.30
309_G634_M0.6700.29
435_L442_W0.6700.29
75_T119_E0.6680.29
438_K443_L0.6680.29
210_F232_G0.6670.29
255_P259_R0.6660.29
437_R442_W0.6660.29
72_N185_N0.6650.29
181_A217_R0.6640.29
477_Y569_A0.6640.29
33_N38_T0.6640.29
443_L451_Q0.6640.29
69_T211_T0.6620.29
181_A214_G0.6620.29
105_L113_A0.6600.29
352_T399_T0.6600.29
281_L424_L0.6590.29
295_A302_G0.6570.29
40_Y212_S0.6570.29
380_V397_G0.6550.29
108_A490_P0.6540.29
183_A601_V0.6540.29
33_N40_Y0.6530.28
521_Y541_R0.6520.28
36_E205_G0.6510.28
66_G182_P0.6510.28
182_P188_M0.6500.28
403_G506_T0.6490.28
192_N195_N0.6490.28
189_W213_A0.6470.28
29_F34_G0.6460.28
519_A572_D0.6450.28
293_Y571_R0.6450.28
179_G237_R0.6450.28
40_Y46_N0.6430.28
20_V31_N0.6430.28
180_F214_G0.6430.28
123_W126_Q0.6430.28
178_D211_T0.6420.28
265_R417_E0.6420.28
320_E477_Y0.6410.28
194_F197_M0.6400.28
178_D214_G0.6400.28
500_C507_P0.6390.28
186_P242_G0.6380.28
211_T219_G0.6380.28
312_Y516_C0.6370.27
31_N181_A0.6360.27
311_L370_M0.6350.27
159_E205_G0.6340.27
67_F70_G0.6330.27
64_E232_G0.6330.27
319_D327_S0.6330.27
64_E178_D0.6330.27
153_W501_Y0.6320.27
568_C617_S0.6320.27
405_W480_A0.6300.27
570_T616_G0.6300.27
593_L656_V0.6300.27
46_N60_F0.6290.27
213_A232_G0.6290.27
131_W521_Y0.6290.27
279_L577_V0.6290.27
46_N174_A0.6280.27
427_Y430_Y0.6280.27
50_V263_S0.6270.27
80_F188_M0.6270.27
130_Q340_L0.6250.27
100_F161_T0.6240.27
334_R524_G0.6230.27
26_D34_G0.6230.27
61_V457_V0.6220.27
180_F213_A0.6220.27
297_E436_S0.6210.27
470_Q606_F0.6210.27
193_L219_G0.6210.27
361_Q458_V0.6210.27
142_L146_G0.6200.26
87_H327_S0.6180.26
509_N512_N0.6180.26
52_F621_C0.6180.26
103_F145_E0.6170.26
530_Y564_C0.6170.26
226_T243_V0.6160.26
485_H516_C0.6150.26
26_D37_E0.6140.26
312_Y498_V0.6140.26
474_L626_C0.6130.26
183_A453_T0.6130.26
185_N214_G0.6120.26
105_L474_L0.6120.26
315_L367_M0.6120.26
334_R337_Y0.6120.26
188_M214_G0.6120.26
25_D184_K0.6110.26
272_G337_Y0.6100.26
24_F63_A0.6090.26
407_C410_E0.6090.26
212_S238_E0.6080.26
180_F188_M0.6070.26
217_R240_L0.6060.26
42_F97_F0.6060.26
210_F219_G0.6060.26
431_Q447_A0.6060.26
26_D179_G0.6050.26
110_L141_L0.6040.26
295_A309_G0.6030.26
258_N269_I0.6020.25
189_W234_G0.6010.25
272_G292_L0.6010.25
48_L79_A0.6000.25
129_A219_G0.5990.25
519_A542_L0.5980.25
83_F92_L0.5980.25
408_P504_Y0.5970.25
198_A244_M0.5970.25
316_S377_A0.5960.25
405_W474_L0.5960.25
214_G236_K0.5960.25
592_S599_E0.5950.25
322_L534_D0.5940.25
29_F33_N0.5940.25
29_F175_W0.5930.25
576_M654_L0.5920.25
329_A406_L0.5910.25
264_K635_S0.5900.25
254_A661_K0.5900.25
316_S573_H0.5900.25
210_F237_R0.5890.25
178_D210_F0.5890.25
65_S157_I0.5870.25
233_F236_K0.5870.25
484_S538_N0.5870.25
214_G232_G0.5870.25
206_T242_G0.5870.25
478_S632_A0.5870.25
605_V650_N0.5860.25
229_K238_E0.5850.24
52_F87_H0.5850.24
213_A229_K0.5850.24
13_F113_A0.5830.24
40_Y44_G0.5830.24
508_Q515_H0.5820.24
534_D569_A0.5820.24
520_S662_G0.5820.24
378_V588_V0.5820.24
329_A364_I0.5800.24
185_N234_G0.5800.24
72_N102_K0.5800.24
101_E104_P0.5800.24
230_R241_C0.5790.24
330_F495_L0.5780.24
501_Y520_S0.5780.24
528_T531_S0.5770.24
149_T285_R0.5770.24
371_D374_A0.5760.24
382_A447_A0.5750.24
294_C412_T0.5740.24
620_L623_A0.5740.24
66_G180_F0.5730.24
351_V403_G0.5730.24
484_S503_G0.5730.24
429_Q443_L0.5720.24
12_E16_E0.5720.24
72_N182_P0.5720.24
71_L213_A0.5700.24
64_E99_S0.5690.24
25_D361_Q0.5690.24
159_E474_L0.5690.24
211_T236_K0.5690.24
107_R375_E0.5680.24
113_A573_H0.5680.24
54_E636_D0.5680.24
68_G179_G0.5670.24
83_F87_H0.5660.23
209_T232_G0.5650.23
616_G627_A0.5650.23
127_L141_L0.5650.23
345_D512_N0.5650.23
74_L104_P0.5640.23
308_Q498_V0.5630.23
435_L609_L0.5630.23
182_P209_T0.5630.23
417_E460_A0.5620.23
463_H632_A0.5620.23
65_S162_S0.5610.23
75_T615_L0.5590.23
109_D574_L0.5590.23
359_K536_Q0.5580.23
335_R340_L0.5570.23
502_D541_R0.5570.23
175_W197_M0.5560.23
582_D606_F0.5560.23
72_N236_K0.5560.23
68_G101_E0.5540.23
38_T519_A0.5540.23
323_N622_S0.5540.23
174_A238_E0.5530.23
129_A556_D0.5530.23
288_W456_V0.5530.23
226_T241_C0.5530.23
390_G608_D0.5530.23
524_G623_A0.5530.23
476_V576_M0.5530.23
393_T564_C0.5530.23
274_I278_L0.5520.23
219_G237_R0.5510.23
308_Q573_H0.5510.23
49_E52_F0.5510.23
50_V536_Q0.5500.23
267_A455_S0.5500.23
456_V461_N0.5500.23
178_D216_V0.5500.23
405_W630_L0.5490.23
253_S257_F0.5490.23
507_P625_L0.5480.23
568_C649_L0.5480.23
34_G38_T0.5480.23
188_M211_T0.5480.23
180_F234_G0.5470.22
194_F216_V0.5470.22
64_E189_W0.5470.22
313_P367_M0.5470.22
68_G189_W0.5460.22
99_S178_D0.5460.22
376_L380_V0.5450.22
141_L335_R0.5450.22
185_N233_F0.5450.22
607_D659_L0.5450.22
265_R455_S0.5440.22
26_D214_G0.5430.22
26_D209_T0.5430.22
185_N216_V0.5420.22
141_L608_D0.5420.22
301_L533_D0.5420.22
136_P222_D0.5410.22
358_E425_Q0.5410.22
108_A265_R0.5410.22
111_A115_Q0.5410.22
378_V388_I0.5410.22
45_G227_M0.5410.22
189_W217_R0.5410.22
127_L150_L0.5400.22
127_L152_L0.5400.22
188_M218_R0.5400.22
299_P426_I0.5400.22
506_T621_C0.5390.22
179_G210_F0.5390.22
73_F143_L0.5370.22
385_V397_G0.5370.22
476_V645_T0.5360.22
200_L574_L0.5360.22
188_M234_G0.5360.22
122_P358_E0.5350.22
501_Y563_R0.5350.22
314_L354_L0.5350.22
332_F624_P0.5340.22
422_Q478_S0.5330.22
188_M196_A0.5320.22
430_Y580_V0.5320.22
112_L369_S0.5320.22
300_A412_T0.5310.22
434_N445_N0.5310.22
267_A588_V0.5310.22
204_G322_L0.5300.22
80_F570_T0.5300.22
308_Q315_L0.5290.22
384_A439_D0.5290.22
310_A507_P0.5280.21
32_D207_L0.5280.21
64_E229_K0.5280.21
520_S537_Q0.5280.21
184_K209_T0.5280.21
417_E421_Q0.5270.21
194_F209_T0.5260.21
60_F95_L0.5250.21
194_F213_A0.5250.21
17_G574_L0.5240.21
200_L521_Y0.5240.21
536_Q540_Q0.5240.21
610_F633_Q0.5240.21
386_E394_N0.5240.21
143_L406_L0.5230.21
521_Y613_A0.5230.21
486_I515_H0.5230.21
292_L421_Q0.5220.21
412_T632_A0.5220.21
435_L441_C0.5220.21
280_S290_V0.5210.21
64_E179_G0.5210.21
314_L521_Y0.5210.21
175_W622_S0.5210.21
400_Y562_A0.5200.21
26_D237_R0.5200.21
352_T397_G0.5190.21
337_Y615_L0.5190.21
525_S529_A0.5190.21
383_N394_N0.5180.21
229_K235_R0.5180.21
102_K156_D0.5180.21
214_G237_R0.5180.21
143_L581_P0.5170.21
170_Q406_L0.5160.21
179_G213_A0.5150.21
64_E71_L0.5150.21
539_R543_I0.5150.21
171_K536_Q0.5140.21
96_H408_P0.5140.21
139_H625_L0.5140.21
127_L132_P0.5130.21
313_P346_H0.5120.21
234_G237_R0.5120.21
396_S582_D0.5110.21
464_Q478_S0.5100.21
413_R427_Y0.5100.21
282_A368_L0.5100.21
63_A398_I0.5100.21
38_T176_F0.5090.21
590_Y603_A0.5090.21
26_D66_G0.5080.21
80_F500_C0.5080.21
211_T311_L0.5080.21
175_W624_P0.5080.21
71_L101_E0.5080.21
384_A387_Q0.5080.21
27_V33_N0.5070.20
385_V396_S0.5070.20
255_P260_T0.5070.20
278_L415_V0.5070.20
360_S364_I0.5070.20
51_R242_G0.5060.20
156_D534_D0.5060.20
22_R38_T0.5050.20
459_L472_S0.5050.20
129_A614_A0.5040.20
298_A413_R0.5040.20
25_D359_K0.5040.20
151_D534_D0.5040.20
71_L175_W0.5040.20
164_L170_Q0.5030.20
108_A228_Q0.5030.20
214_G222_D0.5030.20
45_G208_A0.5020.20
651_P657_R0.5020.20
68_G180_F0.5020.20
242_G364_I0.5020.20
43_L416_L0.5020.20
221_Q227_M0.5010.20
304_S519_A0.5010.20
105_L282_A0.5010.20
178_D232_G0.5010.20
360_S617_S0.5000.20
484_S556_D0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ps9A 1 0.988 100 0.384 Contact Map
3pvcA 1 0.9431 100 0.403 Contact Map
2qy6A 2 0.3638 100 0.757 Contact Map
4h1bA 1 0.5434 100 0.797 Contact Map
1ryiA 4 0.5299 100 0.801 Contact Map
1y56B 1 0.5404 100 0.804 Contact Map
4x9mA 1 0.5374 100 0.809 Contact Map
3axbA 2 0.5464 100 0.812 Contact Map
3dmeA 2 0.5 100 0.813 Contact Map
1c0pA 2 0.518 100 0.814 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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