YFGF - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YFGF - Cyclic di-GMP phosphodiesterase YfgF

UniProt:	P77172	Sequences: MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVFLFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGGYRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMPFNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFALWLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMISIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDPVVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLEPGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRSPVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNHFFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTLQFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALTNVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLDYQIVASICHLARMKKMLVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEIEPIRESA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14202
Length:	747 (614)
Sequences:	5226 (4503)
Seq/√Len:	181.7

ECOLI - YFGF YFEA YEGE DOSP GMR YLIE YHJK CSRD YLAB YJCC RTN YCGG ADRB
BACSU - YKOW

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
525_H	736_T	5.717	1.00
728_G	731_Q	5.129	1.00
563_E	605_K	5.114	1.00
392_E	395_E	4.990	1.00
328_R	332_V	4.862	1.00
670_G	674_R	4.844	1.00
558_D	589_S	4.702	1.00
519_M	722_M	4.602	1.00
637_Q	664_D	4.107	1.00
492_D	543_S	3.839	1.00
705_V	722_M	3.750	1.00
600_S	639_L	3.725	1.00
513_A	568_F	3.521	1.00
559_M	598_E	3.422	1.00
602_L	606_Y	3.347	1.00
694_R	720_D	3.310	1.00
357_C	443_V	3.282	1.00
510_F	532_K	3.270	1.00
708_E	712_E	3.199	1.00
499_R	533_G	3.130	1.00
533_G	537_E	3.120	1.00
454_H	457_L	3.102	1.00
585_L	595_F	3.061	1.00
564_H	567_Q	2.936	1.00
529_L	561_V	2.895	1.00
512_M	732_P	2.883	1.00
344_L	406_A	2.858	1.00
614_I	665_L	2.854	1.00
517_T	727_I	2.818	1.00
659_K	682_D	2.809	1.00
449_R	452_V	2.799	1.00
319_Q	323_V	2.658	1.00
511_L	560_W	2.647	1.00
707_N	710_I	2.621	1.00
548_A	557_I	2.575	1.00
533_G	536_D	2.569	1.00
569_M	608_I	2.511	1.00
534_E	537_E	2.439	1.00
570_A	574_A	2.377	1.00
493_K	550_E	2.374	1.00
529_L	557_I	2.369	1.00
572_N	733_L	2.366	1.00
516_I	524_Y	2.363	1.00
713_A	717_L	2.351	1.00
355_A	447_Y	2.337	1.00
711_R	727_I	2.274	1.00
391_L	397_V	2.265	1.00
711_R	722_M	2.253	1.00
343_A	347_A	2.244	1.00
564_H	568_F	2.238	1.00
359_L	441_I	2.231	1.00
573_R	612_Q	2.181	1.00
347_A	396_D	2.160	1.00
568_F	572_N	2.141	1.00
339_P	343_A	2.139	1.00
563_E	606_Y	2.089	1.00
633_L	643_I	2.085	1.00
644_A	665_L	2.080	1.00
532_K	538_L	2.046	1.00
568_F	733_L	2.045	1.00
378_Q	381_Q	2.021	1.00
509_F	529_L	2.015	1.00
642_Q	664_D	2.010	1.00
587_P	620_S	2.002	1.00
516_I	721_Y	1.961	1.00
732_P	735_D	1.950	1.00
508_H	533_G	1.929	1.00
368_V	376_R	1.923	1.00
418_I	445_Y	1.918	1.00
563_E	602_L	1.887	1.00
382_K	385_H	1.886	1.00
357_C	418_I	1.881	1.00
344_L	398_Y	1.878	1.00
711_R	726_L	1.862	1.00
677_V	709_E	1.858	1.00
348_L	455_I	1.849	1.00
502_Q	508_H	1.846	1.00
502_Q	506_H	1.842	1.00
499_R	536_D	1.828	1.00
516_I	665_L	1.827	1.00
510_F	538_L	1.805	1.00
343_A	396_D	1.805	1.00
545_L	554_S	1.801	1.00
711_R	715_L	1.795	1.00
529_L	560_W	1.794	1.00
358_Y	468_L	1.790	1.00
708_E	726_L	1.779	1.00
511_L	561_V	1.769	1.00
645_I	663_A	1.766	1.00
382_K	430_F	1.766	1.00
511_L	565_T	1.747	1.00
373_I	463_N	1.719	1.00
361_I	383_L	1.718	1.00
677_V	683_Y	1.691	1.00
507_N	564_H	1.690	1.00
702_A	719_I	1.685	1.00
445_Y	481_R	1.664	1.00
666_L	693_A	1.660	1.00
378_Q	433_D	1.652	1.00
670_G	704_Y	1.636	1.00
492_D	536_D	1.623	1.00
419_T	423_S	1.620	1.00
560_W	564_H	1.618	1.00
496_M	547_V	1.597	1.00
452_V	461_E	1.594	1.00
725_Y	730_P	1.588	1.00
585_L	615_F	1.585	1.00
512_M	538_L	1.580	1.00
369_K	469_S	1.575	1.00
566_L	602_L	1.571	1.00
580_R	642_Q	1.562	1.00
690_C	719_I	1.562	1.00
379_Y	430_F	1.560	1.00
665_L	701_V	1.548	1.00
699_L	720_D	1.546	1.00
497_M	501_Q	1.546	1.00
400_L	406_A	1.545	1.00
583_I	613_L	1.541	1.00
463_N	469_S	1.541	1.00
582_A	614_I	1.533	1.00
603_L	641_C	1.521	1.00
683_Y	713_A	1.510	1.00
595_F	599_V	1.508	1.00
533_G	539_I	1.506	1.00
368_V	402_G	1.505	1.00
363_G	497_M	1.499	1.00
367_L	379_Y	1.477	1.00
422_D	443_V	1.469	1.00
599_V	636_L	1.468	1.00
500_L	509_F	1.451	1.00
362_P	442_G	1.446	1.00
650_T	672_F	1.445	1.00
687_A	695_M	1.441	1.00
694_R	700_V	1.437	1.00
312_M	315_L	1.435	1.00
385_H	388_S	1.435	1.00
358_Y	406_A	1.432	1.00
379_Y	439_P	1.431	1.00
360_R	472_T	1.425	1.00
549_H	554_S	1.421	1.00
523_V	739_E	1.404	1.00
731_Q	739_E	1.403	1.00
451_P	481_R	1.391	1.00
363_G	476_E	1.386	1.00
404_D	463_N	1.382	1.00
603_L	608_I	1.380	1.00
609_E	612_Q	1.362	1.00
474_A	480_R	1.360	1.00
566_L	613_L	1.357	1.00
440_Q	477_N	1.340	1.00
508_H	534_E	1.339	1.00
516_I	701_V	1.339	1.00
402_G	469_S	1.335	1.00
562_I	602_L	1.326	1.00
353_W	450_S	1.324	1.00
365_E	469_S	1.321	1.00
320_R	323_V	1.321	1.00
569_M	581_F	1.315	1.00
382_K	386_W	1.309	1.00
511_L	529_L	1.303	1.00
659_K	675_N	1.291	1.00
539_I	545_L	1.289	1.00
676_I	713_A	1.287	1.00
391_L	395_E	1.282	1.00
601_Q	605_K	1.275	1.00
344_L	348_L	1.269	1.00
346_R	396_D	1.262	1.00
536_D	543_S	1.260	1.00
343_A	346_R	1.260	1.00
699_L	721_Y	1.258	1.00
508_H	531_M	1.254	1.00
361_I	441_I	1.253	1.00
677_V	713_A	1.250	1.00
573_R	609_E	1.242	1.00
568_F	737_L	1.240	1.00
425_L	430_F	1.237	1.00
702_A	714_V	1.237	1.00
614_I	644_A	1.234	1.00
690_C	717_L	1.230	1.00
221_L	229_L	1.216	1.00
445_Y	479_Q	1.214	1.00
569_M	573_R	1.213	1.00
663_A	698_M	1.210	1.00
431_F	434_G	1.210	1.00
247_L	251_L	1.209	1.00
693_A	700_V	1.205	1.00
527_I	581_F	1.204	1.00
365_E	368_V	1.204	1.00
580_R	614_I	1.204	1.00
634_Q	638_E	1.200	1.00
448_V	458_L	1.198	1.00
401_S	469_S	1.198	1.00
687_A	691_H	1.197	1.00
633_L	662_N	1.194	1.00
728_G	739_E	1.186	1.00
383_L	425_L	1.186	1.00
471_V	480_R	1.184	1.00
687_A	717_L	1.180	1.00
232_M	240_I	1.174	1.00
364_M	472_T	1.173	1.00
688_S	695_M	1.171	1.00
185_F	188_R	1.170	1.00
562_I	599_V	1.165	1.00
319_Q	322_V	1.164	1.00
407_L	421_L	1.162	1.00
598_E	602_L	1.161	1.00
565_T	581_F	1.157	1.00
260_R	263_Y	1.153	1.00
526_E	584_N	1.151	1.00
395_E	420_A	1.146	1.00
244_N	249_L	1.138	1.00
647_D	703_E	1.137	1.00
735_D	738_N	1.137	1.00
383_L	430_F	1.135	1.00
245_Y	249_L	1.134	1.00
516_I	580_R	1.134	1.00
542_D	546_P	1.129	1.00
369_K	463_N	1.128	1.00
618_T	647_D	1.127	1.00
235_N	239_T	1.122	1.00
712_E	716_S	1.120	1.00
519_M	711_R	1.120	1.00
518_G	522_D	1.117	1.00
360_R	469_S	1.117	1.00
722_M	727_I	1.115	1.00
386_W	429_R	1.113	1.00
418_I	479_Q	1.110	1.00
705_V	714_V	1.110	1.00
376_R	403_N	1.109	1.00
542_D	670_G	1.106	1.00
510_F	732_P	1.105	1.00
378_Q	382_K	1.099	1.00
315_L	319_Q	1.097	1.00
613_L	641_C	1.089	1.00
359_L	407_L	1.089	1.00
368_V	403_N	1.088	1.00
362_P	476_E	1.084	1.00
360_R	403_N	1.083	1.00
562_I	583_I	1.081	1.00
566_L	608_I	1.080	1.00
412_E	417_R	1.079	1.00
500_L	503_A	1.073	1.00
406_A	459_L	1.071	1.00
516_I	614_I	1.070	1.00
403_N	472_T	1.066	1.00
344_L	408_R	1.064	1.00
516_I	582_A	1.063	1.00
325_R	329_L	1.062	1.00
471_V	478_M	1.062	1.00
616_E	667_K	1.061	1.00
731_Q	735_D	1.060	1.00
225_A	229_L	1.060	1.00
431_F	436_P	1.059	1.00
668_I	689_I	1.058	1.00
373_I	469_S	1.058	1.00
425_L	441_I	1.056	1.00
217_A	221_L	1.055	1.00
551_F	554_S	1.054	1.00
221_L	225_A	1.053	1.00
630_Q	662_N	1.051	1.00
630_Q	634_Q	1.050	1.00
244_N	252_P	1.048	1.00
509_F	560_W	1.040	1.00
362_P	472_T	1.037	1.00
331_Y	346_R	1.037	1.00
499_R	535_N	1.033	1.00
323_V	327_Q	1.032	1.00
360_R	368_V	1.032	1.00
213_K	217_A	1.030	1.00
426_K	477_N	1.029	1.00
365_E	369_K	1.028	1.00
725_Y	729_K	1.027	1.00
685_I	692_L	1.026	1.00
524_Y	580_R	1.024	1.00
563_E	567_Q	1.022	0.99
316_A	320_R	1.021	0.99
224_G	227_L	1.020	0.99
220_L	223_L	1.019	0.99
365_E	472_T	1.017	0.99
461_E	487_Q	1.017	0.99
590_V	621_N	1.014	0.99
277_S	285_I	1.013	0.99
548_A	554_S	1.011	0.99
701_V	721_Y	1.008	0.99
333_D	399_Q	1.005	0.99
285_I	288_Y	1.002	0.99
528_L	647_D	1.001	0.99
712_E	715_L	0.993	0.99
585_L	589_S	0.990	0.99
483_A	486_L	0.989	0.99
518_G	720_D	0.988	0.99
348_L	408_R	0.986	0.99
349_R	392_E	0.985	0.99
674_R	710_I	0.983	0.99
368_V	472_T	0.979	0.99
540_S	546_P	0.979	0.99
470_I	473_N	0.974	0.99
285_I	289_P	0.968	0.99
364_M	368_V	0.961	0.99
497_M	547_V	0.960	0.99
401_S	463_N	0.960	0.99
185_F	189_V	0.958	0.99
673_I	686_V	0.955	0.99
683_Y	687_A	0.953	0.99
332_V	343_A	0.952	0.99
422_D	479_Q	0.950	0.99
510_F	529_L	0.946	0.99
219_W	223_L	0.944	0.99
614_I	642_Q	0.941	0.99
265_L	268_L	0.939	0.99
676_I	686_V	0.939	0.99
368_V	377_I	0.938	0.99
184_Y	188_R	0.938	0.99
545_L	618_T	0.938	0.99
575_K	737_L	0.937	0.99
596_P	632_T	0.936	0.99
392_E	420_A	0.933	0.99
373_I	472_T	0.933	0.99
325_R	328_R	0.931	0.99
448_V	452_V	0.929	0.99
708_E	711_R	0.928	0.99
549_H	586_S	0.928	0.99
600_S	635_H	0.926	0.99
559_M	563_E	0.925	0.99
677_V	710_I	0.924	0.99
386_W	430_F	0.921	0.99
375_L	437_M	0.918	0.99
584_N	646_D	0.918	0.99
501_Q	553_L	0.917	0.99
567_Q	606_Y	0.916	0.99
600_S	604_A	0.915	0.99
363_G	550_E	0.913	0.99
557_I	561_V	0.912	0.99
246_T	249_L	0.912	0.99
665_L	721_Y	0.912	0.99
648_F	689_I	0.910	0.99
199_Y	202_Q	0.910	0.99
603_L	610_A	0.909	0.99
567_Q	571_E	0.908	0.99
401_S	404_D	0.906	0.99
364_M	403_N	0.904	0.99
676_I	683_Y	0.903	0.99
536_D	539_I	0.902	0.99
299_S	302_Y	0.901	0.99
444_S	462_L	0.901	0.99
253_L	283_N	0.900	0.99
584_N	667_K	0.899	0.99
414_H	417_R	0.899	0.99
519_M	705_V	0.898	0.99
618_T	703_E	0.894	0.99
225_A	228_L	0.892	0.99
446_C	461_E	0.892	0.99
214_K	218_L	0.890	0.99
370_N	494_V	0.889	0.99
364_M	380_K	0.889	0.99
220_L	225_A	0.888	0.99
626_V	629_A	0.886	0.99
548_A	552_G	0.885	0.99
569_M	606_Y	0.883	0.99
230_L	250_L	0.882	0.99
531_M	537_E	0.882	0.99
217_A	220_L	0.882	0.99
391_L	407_L	0.881	0.98
316_A	319_Q	0.881	0.98
336_V	380_K	0.880	0.98
360_R	376_R	0.879	0.98
293_T	296_T	0.877	0.98
418_I	443_V	0.877	0.98
223_L	227_L	0.870	0.98
257_G	260_R	0.870	0.98
280_S	285_I	0.868	0.98
572_N	737_L	0.868	0.98
375_L	435_M	0.865	0.98
541_P	544_F	0.865	0.98
335_V	377_I	0.865	0.98
470_I	474_A	0.864	0.98
558_D	585_L	0.863	0.98
297_I	306_S	0.861	0.98
341_V	377_I	0.860	0.98
444_S	465_V	0.858	0.98
299_S	303_L	0.858	0.98
555_S	592_Q	0.857	0.98
270_W	273_V	0.856	0.98
284_Y	288_Y	0.856	0.98
366_M	497_M	0.855	0.98
590_V	633_L	0.855	0.98
360_R	365_E	0.854	0.98
224_G	228_L	0.853	0.98
551_F	588_T	0.851	0.98
365_E	404_D	0.849	0.98
504_L	557_I	0.848	0.98
327_Q	331_Y	0.848	0.98
608_I	613_L	0.847	0.98
202_Q	205_Q	0.845	0.98
360_R	373_I	0.844	0.98
432_W	437_M	0.841	0.98
244_N	255_M	0.840	0.98
442_G	475_P	0.840	0.98
451_P	461_E	0.840	0.98
584_N	616_E	0.838	0.98
365_E	373_I	0.836	0.98
513_A	527_I	0.835	0.98
482_G	487_Q	0.835	0.98
365_E	376_R	0.835	0.98
615_F	643_I	0.833	0.98
360_R	404_D	0.832	0.98
424_H	427_Q	0.832	0.98
551_F	555_S	0.832	0.98
321_A	325_R	0.831	0.98
582_A	665_L	0.830	0.98
630_Q	660_N	0.829	0.98
365_E	403_N	0.829	0.98
220_L	229_L	0.828	0.98
539_I	546_P	0.828	0.98
219_W	222_A	0.828	0.98
362_P	475_P	0.826	0.98
282_Q	288_Y	0.826	0.98
603_L	606_Y	0.826	0.98
324_R	327_Q	0.825	0.98
449_R	461_E	0.825	0.98
362_P	477_N	0.825	0.98
296_T	306_S	0.823	0.98
690_C	714_V	0.823	0.98
528_L	703_E	0.822	0.98
222_A	225_A	0.821	0.98
553_L	556_S	0.821	0.98
555_S	589_S	0.819	0.98
281_Y	285_I	0.817	0.98
211_V	215_E	0.816	0.98
528_L	584_N	0.812	0.97
360_R	364_M	0.810	0.97
200_Y	203_L	0.809	0.97
448_V	451_P	0.808	0.97
618_T	651_G	0.807	0.97
597_V	635_H	0.803	0.97
328_R	337_H	0.801	0.97
296_T	299_S	0.799	0.97
168_N	172_L	0.798	0.97
554_S	586_S	0.797	0.97
413_S	417_R	0.796	0.97
442_G	476_E	0.796	0.97
243_T	247_L	0.796	0.97
387_L	397_V	0.795	0.97
690_C	694_R	0.794	0.97
440_Q	475_P	0.791	0.97
346_R	349_R	0.790	0.97
220_L	224_G	0.788	0.97
659_K	679_N	0.788	0.97
526_E	667_K	0.788	0.97
188_R	192_N	0.787	0.97
682_D	710_I	0.786	0.97
339_P	396_D	0.786	0.97
215_E	219_W	0.786	0.97
334_P	337_H	0.785	0.97
318_R	321_A	0.783	0.97
599_V	602_L	0.783	0.97
365_E	402_G	0.782	0.97
530_R	703_E	0.782	0.97
446_C	458_L	0.780	0.97
568_F	571_E	0.780	0.97
244_N	247_L	0.778	0.97
223_L	226_L	0.778	0.97
528_L	618_T	0.778	0.97
291_Y	296_T	0.776	0.97
634_Q	662_N	0.775	0.97
232_M	244_N	0.775	0.97
356_L	458_L	0.774	0.97
528_L	616_E	0.774	0.97
513_A	572_N	0.774	0.97
602_L	605_K	0.774	0.97
365_E	463_N	0.772	0.97
457_L	461_E	0.772	0.97
244_N	254_M	0.771	0.97
596_P	635_H	0.770	0.96
214_K	217_A	0.770	0.96
376_R	402_G	0.768	0.96
426_K	430_F	0.768	0.96
626_V	661_V	0.765	0.96
572_N	736_T	0.764	0.96
374_M	456_Y	0.762	0.96
499_R	534_E	0.761	0.96
230_L	244_N	0.760	0.96
528_L	646_D	0.759	0.96
227_L	231_C	0.759	0.96
688_S	692_L	0.757	0.96
218_L	225_A	0.757	0.96
631_I	635_H	0.756	0.96
224_G	229_L	0.755	0.96
230_L	233_P	0.754	0.96
315_L	320_R	0.754	0.96
573_R	576_M	0.753	0.96
263_Y	267_S	0.752	0.96
308_I	313_A	0.751	0.96
469_S	472_T	0.751	0.96
562_I	613_L	0.749	0.96
618_T	672_F	0.748	0.96
279_H	289_P	0.747	0.96
667_K	723_Q	0.747	0.96
395_E	409_L	0.746	0.96
261_Y	265_L	0.746	0.96
555_S	558_D	0.745	0.96
635_H	638_E	0.744	0.96
222_A	226_L	0.741	0.96
526_E	616_E	0.739	0.96
464_T	486_L	0.739	0.96
344_L	356_L	0.739	0.96
260_R	268_L	0.739	0.96
244_N	248_S	0.738	0.96
396_D	408_R	0.738	0.96
513_A	564_H	0.737	0.95
436_P	502_Q	0.736	0.95
269_L	273_V	0.735	0.95
475_P	478_M	0.734	0.95
442_G	472_T	0.734	0.95
368_V	380_K	0.734	0.95
390_L	421_L	0.733	0.95
390_L	420_A	0.732	0.95
571_E	575_K	0.732	0.95
244_N	251_L	0.731	0.95
511_L	527_I	0.731	0.95
525_H	579_H	0.730	0.95
500_L	548_A	0.730	0.95
559_M	602_L	0.730	0.95
673_I	702_A	0.728	0.95
404_D	472_T	0.728	0.95
304_V	308_I	0.727	0.95
316_A	323_V	0.727	0.95
679_N	682_D	0.726	0.95
124_R	127_W	0.725	0.95
447_Y	481_R	0.725	0.95
549_H	620_S	0.724	0.95
363_G	366_M	0.724	0.95
189_V	192_N	0.723	0.95
565_T	583_I	0.722	0.95
376_R	472_T	0.721	0.95
418_I	422_D	0.721	0.95
463_N	472_T	0.720	0.95
584_N	723_Q	0.718	0.95
642_Q	699_L	0.717	0.95
665_L	699_L	0.715	0.95
495_A	535_N	0.715	0.95
497_M	551_F	0.714	0.95
134_T	137_L	0.713	0.95
291_Y	295_L	0.712	0.95
161_F	164_G	0.709	0.94
503_A	509_F	0.708	0.94
123_Q	126_F	0.707	0.94
243_T	253_L	0.707	0.94
335_V	368_V	0.706	0.94
529_L	544_F	0.705	0.94
347_A	398_Y	0.704	0.94
526_E	723_Q	0.703	0.94
164_G	168_N	0.703	0.94
599_V	641_C	0.703	0.94
470_I	480_R	0.701	0.94
196_L	199_Y	0.701	0.94
260_R	266_I	0.701	0.94
184_Y	192_N	0.700	0.94
449_R	458_L	0.699	0.94
134_T	138_I	0.699	0.94
599_V	615_F	0.698	0.94
259_M	263_Y	0.698	0.94
392_E	412_E	0.697	0.94
360_R	463_N	0.694	0.94
514_Q	723_Q	0.694	0.94
623_L	657_R	0.693	0.94
367_L	376_R	0.693	0.94
256_W	260_R	0.693	0.94
266_I	269_L	0.691	0.94
384_S	397_V	0.691	0.94
202_Q	206_Q	0.691	0.94
219_W	228_L	0.690	0.94
504_L	507_N	0.690	0.94
522_D	578_A	0.690	0.94
207_V	210_K	0.689	0.94
442_G	469_S	0.688	0.94
348_L	356_L	0.687	0.93
260_R	265_L	0.687	0.93
133_A	137_L	0.687	0.93
590_V	595_F	0.687	0.93
330_A	365_E	0.687	0.93
397_V	407_L	0.686	0.93
622_A	657_R	0.684	0.93
296_T	302_Y	0.683	0.93
505_E	556_S	0.682	0.93
554_S	588_T	0.682	0.93
294_Q	297_I	0.681	0.93
379_Y	432_W	0.680	0.93
691_H	695_M	0.680	0.93
496_M	499_R	0.678	0.93
315_L	318_R	0.678	0.93
354_S	458_L	0.676	0.93
334_P	342_R	0.676	0.93
169_Y	172_L	0.675	0.93
165_T	168_N	0.669	0.93
419_T	422_D	0.669	0.93
289_P	296_T	0.669	0.93
367_L	437_M	0.667	0.92
358_Y	400_L	0.667	0.92
371_Y	375_L	0.666	0.92
196_L	200_Y	0.663	0.92
521_G	708_E	0.662	0.92
581_F	608_I	0.661	0.92
495_A	499_R	0.661	0.92
502_Q	505_E	0.660	0.92
365_E	442_G	0.658	0.92
692_L	696_K	0.658	0.92
570_A	606_Y	0.658	0.92
362_P	469_S	0.657	0.92
402_G	463_N	0.657	0.92
650_T	671_S	0.657	0.92
263_Y	269_L	0.656	0.92
224_G	242_S	0.656	0.92
666_L	698_M	0.653	0.92
221_L	224_G	0.653	0.92
233_P	240_I	0.651	0.92
528_L	725_Y	0.651	0.92
198_S	205_Q	0.651	0.92
292_T	295_L	0.651	0.92
625_N	628_Q	0.651	0.92
584_N	703_E	0.650	0.91
404_D	442_G	0.650	0.91
268_L	271_A	0.649	0.91
597_V	601_Q	0.648	0.91
265_L	269_L	0.648	0.91
282_Q	285_I	0.648	0.91
206_Q	210_K	0.647	0.91
511_L	562_I	0.646	0.91
322_V	329_L	0.645	0.91
419_T	479_Q	0.644	0.91
545_L	548_A	0.644	0.91
608_I	612_Q	0.644	0.91
214_K	224_G	0.643	0.91
230_L	234_L	0.643	0.91
373_I	404_D	0.643	0.91
562_I	615_F	0.643	0.91
570_A	573_R	0.643	0.91
207_V	213_K	0.643	0.91
207_V	211_V	0.642	0.91
591_C	624_T	0.642	0.91
357_C	445_Y	0.642	0.91
514_Q	528_L	0.641	0.91
218_L	223_L	0.641	0.91
360_R	369_K	0.641	0.91
706_E	725_Y	0.640	0.91
484_M	488_R	0.640	0.91
266_I	270_W	0.640	0.91
159_M	162_N	0.639	0.91
545_L	549_H	0.638	0.91
328_R	331_Y	0.636	0.91
616_E	723_Q	0.636	0.91
364_M	376_R	0.634	0.90
122_S	126_F	0.634	0.90
647_D	651_G	0.633	0.90
317_T	321_A	0.633	0.90
566_L	606_Y	0.632	0.90
685_I	689_I	0.632	0.90
168_N	171_A	0.632	0.90
517_T	739_E	0.630	0.90
657_R	660_N	0.629	0.90
491_K	495_A	0.627	0.90
399_Q	402_G	0.627	0.90
423_S	427_Q	0.627	0.90
554_S	558_D	0.626	0.90
588_T	621_N	0.625	0.90
195_Y	202_Q	0.624	0.90
468_L	476_E	0.624	0.90
520_R	720_D	0.624	0.90
668_I	672_F	0.623	0.90
341_V	463_N	0.622	0.90
235_N	238_S	0.621	0.90
438_Q	501_Q	0.621	0.90
383_L	387_L	0.619	0.89
347_A	408_R	0.618	0.89
490_L	494_V	0.617	0.89
632_T	635_H	0.616	0.89
141_Q	145_F	0.616	0.89
221_L	226_L	0.616	0.89
667_K	703_E	0.615	0.89
470_I	489_E	0.615	0.89
381_Q	385_H	0.615	0.89
592_Q	596_P	0.615	0.89
659_K	685_I	0.614	0.89
422_D	477_N	0.613	0.89
217_A	229_L	0.612	0.89
616_E	619_E	0.612	0.89
158_V	171_A	0.611	0.89
539_I	543_S	0.610	0.89
249_L	252_P	0.609	0.89
312_M	316_A	0.608	0.89
158_V	161_F	0.607	0.88
230_L	313_A	0.606	0.88
124_R	128_Q	0.605	0.88
331_Y	342_R	0.605	0.88
280_S	283_N	0.605	0.88
373_I	403_N	0.605	0.88
266_I	273_V	0.602	0.88
371_Y	435_M	0.602	0.88
138_I	141_Q	0.601	0.88
181_P	188_R	0.599	0.88
354_S	448_V	0.599	0.88
181_P	185_F	0.599	0.88
733_L	737_L	0.598	0.88
326_I	329_L	0.597	0.88
616_E	703_E	0.597	0.88
248_S	251_L	0.597	0.88
357_C	407_L	0.596	0.88
404_D	469_S	0.595	0.87
248_S	255_M	0.594	0.87
215_E	223_L	0.593	0.87
282_Q	286_P	0.593	0.87
344_L	400_L	0.592	0.87
524_Y	579_H	0.591	0.87
202_Q	210_K	0.590	0.87
264_K	268_L	0.590	0.87
139_L	143_A	0.590	0.87
586_S	618_T	0.589	0.87
226_L	231_C	0.589	0.87
556_S	559_M	0.588	0.87
252_P	256_W	0.587	0.87
361_I	463_N	0.587	0.87
623_L	629_A	0.587	0.87
233_P	244_N	0.586	0.87
530_R	616_E	0.586	0.87
580_R	612_Q	0.586	0.87
259_M	262_G	0.585	0.87
161_F	167_I	0.585	0.87
230_L	247_L	0.585	0.87
213_K	216_F	0.584	0.86
669_D	703_E	0.583	0.86
621_N	657_R	0.583	0.86
195_Y	199_Y	0.583	0.86
141_Q	144_A	0.582	0.86
423_S	426_K	0.579	0.86
571_E	574_A	0.578	0.86
737_L	740_I	0.578	0.86
684_Q	695_M	0.578	0.86
234_L	238_S	0.577	0.86
402_G	442_G	0.577	0.86
265_L	273_V	0.577	0.86
357_C	409_L	0.577	0.86
584_N	619_E	0.576	0.86
231_C	235_N	0.576	0.86
514_Q	667_K	0.576	0.86
245_Y	248_S	0.575	0.86
299_S	304_V	0.575	0.86
252_P	255_M	0.574	0.86
122_S	129_I	0.573	0.85
733_L	736_T	0.573	0.85
258_A	263_Y	0.573	0.85
258_A	265_L	0.572	0.85
401_S	442_G	0.571	0.85
161_F	171_A	0.570	0.85
736_T	739_E	0.570	0.85
614_I	701_V	0.570	0.85
651_G	703_E	0.570	0.85
532_K	537_E	0.569	0.85
142_F	145_F	0.568	0.85
362_P	440_Q	0.568	0.85
584_N	647_D	0.568	0.85
240_I	247_L	0.567	0.85
647_D	650_T	0.567	0.85
703_E	725_Y	0.567	0.85
677_V	707_N	0.567	0.85
625_N	629_A	0.567	0.85
259_M	266_I	0.566	0.85
165_T	171_A	0.566	0.85
710_I	726_L	0.566	0.85
375_L	432_W	0.565	0.85
584_N	706_E	0.565	0.85
496_M	536_D	0.565	0.85
554_S	618_T	0.565	0.85
521_G	711_R	0.565	0.85
521_G	715_L	0.565	0.85
375_L	378_Q	0.565	0.85
530_R	584_N	0.565	0.85
528_L	619_E	0.564	0.85
214_K	225_A	0.564	0.85
637_Q	662_N	0.563	0.84
545_L	703_E	0.563	0.84
335_V	376_R	0.563	0.84
584_N	725_Y	0.562	0.84
323_V	326_I	0.562	0.84
220_L	228_L	0.561	0.84
629_A	632_T	0.561	0.84
263_Y	266_I	0.561	0.84
587_P	617_V	0.561	0.84
643_I	664_D	0.560	0.84
194_F	199_Y	0.559	0.84
369_K	373_I	0.559	0.84
302_Y	309_V	0.559	0.84
598_E	601_Q	0.558	0.84
242_S	245_Y	0.558	0.84
369_K	404_D	0.557	0.84
517_T	521_G	0.557	0.84
531_M	719_I	0.556	0.84
347_A	410_N	0.555	0.84
580_R	721_Y	0.555	0.84
713_A	716_S	0.555	0.84
528_L	706_E	0.555	0.84
362_P	404_D	0.554	0.84
322_V	325_R	0.554	0.84
377_I	402_G	0.553	0.83
329_L	332_V	0.553	0.83
226_L	229_L	0.553	0.83
545_L	586_S	0.552	0.83
137_L	146_V	0.552	0.83
569_M	612_Q	0.551	0.83
573_R	577_P	0.551	0.83
295_L	302_Y	0.551	0.83
583_I	641_C	0.550	0.83
122_S	125_I	0.549	0.83
338_L	384_S	0.549	0.83
302_Y	305_F	0.549	0.83
377_I	399_Q	0.549	0.83
373_I	377_I	0.548	0.83
279_H	284_Y	0.548	0.83
616_E	646_D	0.548	0.83
244_N	250_L	0.547	0.83
549_H	618_T	0.546	0.83
124_R	131_F	0.545	0.83
510_F	734_I	0.545	0.83
559_M	601_Q	0.545	0.83
558_D	561_V	0.545	0.83
570_A	608_I	0.545	0.83
401_S	472_T	0.544	0.82
290_G	293_T	0.543	0.82
647_D	725_Y	0.543	0.82
134_T	141_Q	0.543	0.82
618_T	650_T	0.542	0.82
675_N	678_S	0.542	0.82
364_M	442_G	0.542	0.82
446_C	452_V	0.542	0.82
660_N	681_L	0.542	0.82
615_F	641_C	0.542	0.82
513_A	525_H	0.540	0.82
618_T	652_Y	0.540	0.82
541_P	546_P	0.539	0.82
131_F	134_T	0.538	0.82
206_Q	211_V	0.537	0.82
373_I	376_R	0.537	0.82
360_R	442_G	0.536	0.81
532_K	536_D	0.535	0.81
385_H	389_P	0.535	0.81
211_V	214_K	0.535	0.81
442_G	463_N	0.534	0.81
218_L	222_A	0.534	0.81
277_S	289_P	0.533	0.81
345_N	456_Y	0.532	0.81
373_I	442_G	0.532	0.81
300_S	304_V	0.532	0.81
514_Q	584_N	0.530	0.81
714_V	719_I	0.530	0.81
362_P	365_E	0.529	0.81
514_Q	646_D	0.529	0.81
317_T	320_R	0.529	0.81
220_L	226_L	0.529	0.81
304_V	309_V	0.529	0.81
269_L	272_V	0.528	0.81
167_I	170_Q	0.528	0.81
218_L	224_G	0.528	0.81
563_E	598_E	0.527	0.80
248_S	252_P	0.527	0.80
295_L	298_T	0.526	0.80
526_E	646_D	0.526	0.80
195_Y	200_Y	0.525	0.80
122_S	130_V	0.525	0.80
199_Y	203_L	0.524	0.80
376_R	401_S	0.523	0.80
523_V	740_I	0.522	0.80
690_C	700_V	0.521	0.80
265_L	270_W	0.520	0.80
331_Y	339_P	0.520	0.80
706_E	710_I	0.519	0.79
499_R	537_E	0.519	0.79
199_Y	206_Q	0.519	0.79
706_E	729_K	0.519	0.79
645_I	657_R	0.518	0.79
257_G	261_Y	0.518	0.79
162_N	165_T	0.517	0.79
371_Y	494_V	0.517	0.79
528_L	667_K	0.517	0.79
161_F	172_L	0.517	0.79
525_H	581_F	0.517	0.79
256_W	259_M	0.516	0.79
354_S	408_R	0.516	0.79
137_L	145_F	0.516	0.79
335_V	402_G	0.515	0.79
594_R	597_V	0.514	0.79
487_Q	491_K	0.512	0.78
406_A	468_L	0.512	0.78
514_Q	706_E	0.512	0.78
590_V	632_T	0.511	0.78
525_H	572_N	0.511	0.78
232_M	309_V	0.511	0.78
302_Y	307_F	0.510	0.78
446_C	462_L	0.510	0.78
619_E	651_G	0.509	0.78
258_A	261_Y	0.509	0.78
215_E	218_L	0.507	0.78
341_V	401_S	0.507	0.78
170_Q	173_L	0.507	0.78
229_L	233_P	0.506	0.78
229_L	314_V	0.506	0.78
258_A	262_G	0.506	0.78
300_S	303_L	0.505	0.78
157_G	170_Q	0.505	0.78
623_L	645_I	0.504	0.77
628_Q	632_T	0.504	0.77
507_N	563_E	0.504	0.77
240_I	244_N	0.504	0.77
213_K	218_L	0.503	0.77
189_V	193_P	0.503	0.77
395_E	410_N	0.503	0.77
499_R	531_M	0.503	0.77
656_A	671_S	0.502	0.77
513_A	581_F	0.501	0.77
291_Y	314_V	0.501	0.77
210_K	217_A	0.500	0.77
331_Y	343_A	0.500	0.77
318_R	322_V	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.5408	100	0.343	Contact Map
4j40A	2	0.3333	100	0.355	Contact Map
3pjxA	1	0.5435	100	0.368	Contact Map
3gfzA	2	0.4926	100	0.46	Contact Map
4hjfA	1	0.3454	100	0.486	Contact Map
3sy8A	6	0.5234	100	0.56	Contact Map
4hu4A	1	0.3266	100	0.563	Contact Map
4kieA	1	0.3454	100	0.564	Contact Map
2r6oA	2	0.34	100	0.567	Contact Map
4rniA	2	0.336	100	0.571	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0156 seconds.