HLDE - ECOLI - GREMLIN Contacts

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HLDE - Bifunctional protein HldE

UniProt:	P76658	Sequences: MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQQDKKG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13416
Length:	477 (462)
Sequences:	893 (623)
Seq/√Len:	29.0

ECOLI - HLDE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
382_R	415_D	7.228	1.00
381_K	386_D	5.069	1.00
393_L	411_S	4.300	1.00
374_V	397_M	4.260	1.00
232_R	238_S	4.077	1.00
376_S	411_S	3.960	1.00
376_S	413_E	3.895	1.00
343_V	367_G	3.670	1.00
73_T	79_A	3.649	1.00
390_V	468_I	3.519	1.00
425_L	449_N	3.357	1.00
436_K	439_E	3.356	1.00
433_G	455_V	3.287	1.00
148_V	271_A	3.165	1.00
50_P	82_L	3.121	1.00
437_P	447_W	3.119	1.00
325_E	419_R	2.908	1.00
340_E	369_R	2.887	1.00
443_S	447_W	2.853	1.00
351_I	391_N	2.844	1.00
378_A	382_R	2.837	1.00
289_A	293_V	2.749	1.00
422_A	445_E	2.739	1.00
395_Q	462_C	2.692	1.00
238_S	248_H	2.684	1.00
357_V	399_V	2.672	1.00
440_I	455_V	2.659	1.00
60_I	65_A	2.659	1.00
175_L	267_I	2.647	1.00
41_V	109_V	2.619	1.00
344_M	373_A	2.508	0.99
148_V	267_I	2.496	0.99
378_A	413_E	2.490	0.99
145_G	172_V	2.483	0.99
341_K	428_L	2.448	0.99
218_K	222_D	2.424	0.99
297_K	307_E	2.368	0.99
358_S	459_E	2.272	0.99
60_I	272_A	2.228	0.98
418_Q	445_E	2.202	0.98
75_I	80_R	2.190	0.98
419_R	422_A	2.102	0.98
109_V	367_G	2.093	0.98
336_R	342_V	2.084	0.97
199_F	230_V	2.073	0.97
293_V	296_G	2.050	0.97
12_G	145_G	2.046	0.97
354_A	395_Q	1.997	0.97
344_M	441_A	1.991	0.97
12_G	66_N	1.969	0.96
190_T	226_S	1.968	0.96
359_Y	458_F	1.936	0.96
273_T	278_N	1.925	0.96
217_M	220_I	1.889	0.95
62_S	302_T	1.853	0.95
354_A	462_C	1.849	0.95
161_Q	165_Q	1.842	0.95
429_L	442_G	1.823	0.94
55_N	59_N	1.807	0.94
180_G	185_R	1.799	0.94
60_I	67_A	1.797	0.94
146_A	173_P	1.796	0.94
425_L	448_A	1.784	0.94
335_A	408_W	1.767	0.93
446_V	453_V	1.760	0.93
332_V	371_I	1.757	0.93
422_A	448_A	1.754	0.93
75_I	99_P	1.746	0.93
418_Q	441_A	1.741	0.93
445_E	449_N	1.738	0.93
433_G	458_F	1.732	0.93
109_V	117_I	1.731	0.93
149_L	157_L	1.727	0.93
29_T	111_S	1.706	0.92
348_V	380_T	1.686	0.92
366_L	456_L	1.678	0.92
109_V	119_L	1.677	0.91
341_K	452_E	1.675	0.91
50_P	85_S	1.663	0.91
260_T	335_A	1.659	0.91
54_A	153_A	1.655	0.91
446_V	450_G	1.651	0.91
358_S	362_N	1.650	0.91
362_N	365_K	1.649	0.91
149_L	160_V	1.642	0.91
57_A	69_L	1.634	0.90
109_V	343_V	1.633	0.90
14_M	144_I	1.622	0.90
54_A	57_A	1.621	0.90
173_P	190_T	1.615	0.90
251_T	269_V	1.580	0.89
362_N	457_N	1.562	0.88
361_A	405_A	1.555	0.88
50_P	54_A	1.551	0.88
24_Y	343_V	1.531	0.87
227_A	280_L	1.527	0.87
15_V	367_G	1.509	0.86
110_L	298_L	1.500	0.86
232_R	235_Q	1.492	0.86
101_H	373_A	1.476	0.85
191_L	284_C	1.471	0.85
24_Y	367_G	1.470	0.85
15_V	343_V	1.469	0.85
87_A	131_Q	1.466	0.85
13_V	146_A	1.458	0.84
437_P	443_S	1.446	0.84
399_V	405_A	1.443	0.84
340_E	367_G	1.430	0.83
138_N	166_L	1.424	0.83
229_L	237_M	1.423	0.83
397_M	411_S	1.418	0.83
216_G	240_L	1.416	0.83
392_P	395_Q	1.409	0.82
362_N	456_L	1.407	0.82
196_L	235_Q	1.406	0.82
466_N	469_K	1.401	0.82
335_A	369_R	1.389	0.81
267_I	271_A	1.388	0.81
82_L	284_C	1.385	0.81
192_L	225_L	1.384	0.81
378_A	381_K	1.380	0.81
29_T	32_I	1.379	0.81
336_R	339_G	1.363	0.80
369_R	408_W	1.357	0.80
82_L	103_T	1.351	0.80
328_L	332_V	1.347	0.79
265_T	300_T	1.346	0.79
241_Q	281_E	1.339	0.79
48_E	81_A	1.337	0.79
57_A	61_A	1.337	0.79
329_K	424_I	1.336	0.79
187_R	224_E	1.331	0.78
178_P	258_D	1.331	0.78
358_S	398_I	1.330	0.78
176_I	189_A	1.330	0.78
433_G	456_L	1.329	0.78
83_S	97_S	1.327	0.78
340_E	343_V	1.324	0.78
29_T	260_T	1.315	0.78
282_E	285_F	1.314	0.78
391_N	395_Q	1.312	0.77
25_W	43_V	1.311	0.77
265_T	294_V	1.306	0.77
197_S	201_A	1.287	0.76
378_A	415_D	1.273	0.75
380_T	393_L	1.262	0.75
361_A	398_I	1.258	0.74
168_R	226_S	1.257	0.74
333_A	337_K	1.255	0.74
446_V	451_G	1.254	0.74
343_V	366_L	1.249	0.74
229_L	239_L	1.248	0.74
216_G	241_Q	1.245	0.74
325_E	423_G	1.234	0.73
333_A	336_R	1.221	0.72
294_V	300_T	1.219	0.72
249_M	289_A	1.219	0.72
374_V	411_S	1.213	0.72
208_T	211_E	1.210	0.71
203_V	219_L	1.209	0.71
371_I	424_I	1.208	0.71
15_V	24_Y	1.203	0.71
147_L	167_A	1.196	0.71
335_A	340_E	1.195	0.70
11_A	275_A	1.177	0.69
49_R	260_T	1.173	0.69
49_R	367_G	1.169	0.69
212_I	220_I	1.164	0.68
232_R	248_H	1.157	0.68
324_T	327_E	1.149	0.67
59_N	300_T	1.148	0.67
340_E	408_W	1.146	0.67
77_D	80_R	1.145	0.67
16_V	147_L	1.143	0.67
220_I	242_P	1.139	0.67
441_A	458_F	1.136	0.66
130_P	134_H	1.130	0.66
175_L	274_L	1.129	0.66
329_K	338_R	1.127	0.66
70_V	137_I	1.125	0.66
240_L	467_I	1.125	0.66
24_Y	49_R	1.114	0.65
438_E	443_S	1.112	0.65
391_N	402_A	1.112	0.65
381_K	394_E	1.109	0.65
425_L	445_E	1.109	0.65
23_R	48_E	1.108	0.65
269_V	290_A	1.105	0.64
466_N	470_K	1.097	0.64
366_L	454_L	1.094	0.63
213_V	238_S	1.088	0.63
146_A	271_A	1.086	0.63
433_G	457_N	1.080	0.62
418_Q	422_A	1.078	0.62
43_V	54_A	1.074	0.62
351_I	467_I	1.074	0.62
251_T	292_G	1.073	0.62
54_A	71_G	1.071	0.62
34_P	154_K	1.060	0.61
269_V	286_F	1.056	0.61
119_L	390_V	1.055	0.61
440_I	447_W	1.054	0.61
128_V	133_L	1.048	0.60
68_R	144_I	1.046	0.60
73_T	93_C	1.044	0.60
130_P	133_L	1.037	0.59
344_M	425_L	1.028	0.59
71_G	102_P	1.027	0.59
28_P	44_N	1.026	0.58
141_L	147_L	1.023	0.58
445_E	448_A	1.021	0.58
402_A	405_A	1.016	0.58
393_L	397_M	1.015	0.58
154_K	179_K	1.008	0.57
34_P	40_V	1.003	0.57
34_P	258_D	0.991	0.56
12_G	68_R	0.991	0.56
429_L	440_I	0.980	0.55
260_T	300_T	0.979	0.55
16_V	163_M	0.978	0.55
216_G	455_V	0.976	0.55
92_K	97_S	0.975	0.55
200_E	206_C	0.974	0.54
119_L	367_G	0.973	0.54
329_K	423_G	0.973	0.54
107_L	121_F	0.970	0.54
416_T	434_D	0.969	0.54
23_R	105_T	0.967	0.54
357_V	402_A	0.966	0.54
188_G	224_E	0.964	0.54
199_F	215_R	0.964	0.54
374_V	393_L	0.961	0.53
414_E	419_R	0.958	0.53
166_L	170_A	0.957	0.53
256_V	259_V	0.951	0.53
49_R	343_V	0.950	0.53
373_A	420_L	0.950	0.53
417_P	434_D	0.944	0.52
26_Y	45_T	0.943	0.52
371_I	423_G	0.938	0.52
332_V	336_R	0.933	0.51
186_Y	288_N	0.932	0.51
115_Q	256_V	0.931	0.51
105_T	121_F	0.927	0.51
122_E	154_K	0.924	0.51
59_N	265_T	0.924	0.51
293_V	300_T	0.923	0.50
143_S	146_A	0.920	0.50
217_M	240_L	0.917	0.50
321_G	325_E	0.915	0.50
279_S	282_E	0.915	0.50
34_P	56_V	0.910	0.49
393_L	402_A	0.909	0.49
399_V	402_A	0.906	0.49
395_Q	408_W	0.905	0.49
26_Y	110_L	0.905	0.49
216_G	246_P	0.904	0.49
276_A	279_S	0.904	0.49
425_L	441_A	0.903	0.49
387_S	405_A	0.902	0.49
15_V	109_V	0.900	0.49
55_N	265_T	0.898	0.49
19_V	69_L	0.897	0.48
279_S	459_E	0.897	0.48
240_L	465_T	0.897	0.48
19_V	71_G	0.893	0.48
403_L	410_V	0.892	0.48
179_K	259_V	0.891	0.48
190_T	274_L	0.884	0.47
375_N	417_P	0.882	0.47
90_N	425_L	0.879	0.47
193_T	267_I	0.878	0.47
43_V	121_F	0.875	0.47
73_T	97_S	0.867	0.46
32_I	174_V	0.865	0.46
354_A	399_V	0.862	0.46
186_Y	256_V	0.858	0.45
24_Y	119_L	0.857	0.45
142_S	170_A	0.855	0.45
153_A	192_L	0.853	0.45
112_R	200_E	0.847	0.45
20_M	34_P	0.847	0.45
372_V	406_V	0.847	0.45
328_L	467_I	0.845	0.44
393_L	413_E	0.844	0.44
81_A	84_K	0.842	0.44
66_N	342_V	0.839	0.44
137_I	147_L	0.836	0.44
381_K	387_S	0.836	0.44
57_A	91_V	0.833	0.44
243_G	364_R	0.832	0.43
339_G	433_G	0.830	0.43
203_V	223_Y	0.826	0.43
178_P	182_D	0.824	0.43
186_Y	258_D	0.822	0.43
112_R	260_T	0.818	0.42
200_E	260_T	0.815	0.42
75_I	100_T	0.813	0.42
115_Q	122_E	0.812	0.42
252_Q	292_G	0.811	0.42
343_V	433_G	0.811	0.42
196_L	455_V	0.810	0.42
56_V	154_K	0.807	0.42
91_V	94_D	0.805	0.41
34_P	179_K	0.804	0.41
130_P	158_A	0.803	0.41
266_V	442_G	0.799	0.41
153_A	270_L	0.798	0.41
20_M	154_K	0.797	0.41
154_K	186_Y	0.795	0.41
225_L	228_L	0.795	0.41
230_V	348_V	0.794	0.41
119_L	343_V	0.793	0.40
68_R	92_K	0.788	0.40
273_T	338_R	0.784	0.40
438_E	448_A	0.784	0.40
268_G	365_K	0.783	0.40
154_K	259_V	0.780	0.39
421_I	449_N	0.779	0.39
31_R	34_P	0.775	0.39
115_Q	442_G	0.774	0.39
101_H	455_V	0.774	0.39
425_L	447_W	0.772	0.39
449_N	461_G	0.770	0.39
286_F	293_V	0.769	0.39
366_L	405_A	0.769	0.39
410_V	420_L	0.763	0.38
115_Q	186_Y	0.763	0.38
180_G	223_Y	0.762	0.38
192_L	223_Y	0.759	0.38
137_I	163_M	0.758	0.38
38_V	41_V	0.757	0.38
416_T	442_G	0.757	0.38
67_A	272_A	0.754	0.38
193_T	266_V	0.752	0.37
457_N	460_D	0.752	0.37
229_L	301_S	0.750	0.37
122_E	186_Y	0.748	0.37
111_S	284_C	0.748	0.37
94_D	136_R	0.748	0.37
344_M	440_I	0.746	0.37
25_W	216_G	0.745	0.37
437_P	455_V	0.744	0.37
84_K	88_D	0.738	0.36
66_N	162_Q	0.737	0.36
391_N	467_I	0.736	0.36
428_L	452_E	0.734	0.36
300_T	438_E	0.732	0.36
55_N	63_L	0.732	0.36
165_Q	333_A	0.731	0.36
326_E	329_K	0.731	0.36
153_A	193_T	0.729	0.36
336_R	405_A	0.729	0.36
157_L	183_F	0.727	0.36
101_H	344_M	0.727	0.36
46_I	121_F	0.724	0.35
122_E	441_A	0.723	0.35
15_V	119_L	0.722	0.35
293_V	303_V	0.719	0.35
422_A	425_L	0.719	0.35
359_Y	391_N	0.718	0.35
71_G	219_L	0.716	0.35
85_S	89_V	0.716	0.35
12_G	70_V	0.715	0.35
249_M	284_C	0.712	0.35
344_M	445_E	0.712	0.35
207_K	211_E	0.711	0.34
346_N	429_L	0.711	0.34
56_V	297_K	0.707	0.34
354_A	358_S	0.706	0.34
271_A	289_A	0.705	0.34
180_G	183_F	0.703	0.34
74_G	265_T	0.703	0.34
77_D	390_V	0.701	0.34
54_A	105_T	0.699	0.34
34_P	259_V	0.697	0.33
204_G	229_L	0.697	0.33
61_A	71_G	0.696	0.33
107_L	203_V	0.695	0.33
352_L	403_L	0.693	0.33
391_N	411_S	0.693	0.33
224_E	242_P	0.693	0.33
122_E	442_G	0.692	0.33
294_V	303_V	0.692	0.33
30_S	197_S	0.692	0.33
55_N	176_I	0.691	0.33
96_V	228_L	0.690	0.33
441_A	445_E	0.689	0.33
25_W	359_Y	0.688	0.33
186_Y	442_G	0.687	0.33
174_V	289_A	0.686	0.33
326_E	423_G	0.686	0.33
181_T	399_V	0.685	0.33
81_A	85_S	0.685	0.33
418_Q	459_E	0.685	0.33
83_S	93_C	0.684	0.33
353_H	388_R	0.682	0.32
351_I	359_Y	0.681	0.32
15_V	26_Y	0.681	0.32
325_E	342_V	0.681	0.32
65_A	272_A	0.680	0.32
192_L	228_L	0.680	0.32
161_Q	164_I	0.680	0.32
328_L	408_W	0.679	0.32
35_E	453_V	0.679	0.32
212_I	215_R	0.678	0.32
88_D	427_D	0.677	0.32
447_W	455_V	0.677	0.32
281_E	424_I	0.677	0.32
59_N	179_K	0.677	0.32
58_M	373_A	0.675	0.32
186_Y	266_V	0.675	0.32
34_P	233_S	0.674	0.32
230_V	244_K	0.674	0.32
12_G	144_I	0.671	0.32
154_K	178_P	0.671	0.32
398_I	408_W	0.670	0.32
186_Y	429_L	0.670	0.32
192_L	306_I	0.669	0.32
427_D	451_G	0.666	0.31
138_N	169_K	0.664	0.31
113_N	257_Y	0.664	0.31
183_F	302_T	0.664	0.31
20_M	259_V	0.663	0.31
91_V	95_F	0.662	0.31
154_K	256_V	0.662	0.31
273_T	286_F	0.660	0.31
200_E	230_V	0.659	0.31
397_M	401_G	0.659	0.31
343_V	430_V	0.659	0.31
183_F	297_K	0.659	0.31
154_K	288_N	0.658	0.31
83_S	138_N	0.658	0.31
256_V	307_E	0.658	0.31
55_N	346_N	0.658	0.31
258_D	429_L	0.657	0.31
34_P	178_P	0.657	0.31
218_K	313_R	0.656	0.31
250_P	296_G	0.655	0.31
47_E	453_V	0.655	0.31
358_S	402_A	0.654	0.31
75_I	139_Q	0.654	0.31
342_V	369_R	0.653	0.31
373_A	400_L	0.653	0.31
199_F	212_I	0.651	0.30
143_S	171_G	0.649	0.30
199_F	206_C	0.646	0.30
266_V	288_N	0.646	0.30
117_I	465_T	0.643	0.30
321_G	328_L	0.643	0.30
70_V	169_K	0.641	0.30
138_N	162_Q	0.641	0.30
227_A	237_M	0.640	0.30
55_N	294_V	0.640	0.30
259_V	297_K	0.640	0.30
156_A	275_A	0.640	0.30
62_S	192_L	0.639	0.30
89_V	428_L	0.639	0.30
24_Y	54_A	0.637	0.29
199_F	207_K	0.637	0.29
288_N	429_L	0.637	0.29
56_V	256_V	0.636	0.29
270_L	284_C	0.635	0.29
435_Y	441_A	0.635	0.29
223_Y	467_I	0.632	0.29
274_L	364_R	0.632	0.29
267_I	294_V	0.632	0.29
118_R	122_E	0.630	0.29
10_R	73_T	0.628	0.29
176_I	254_Q	0.628	0.29
20_M	179_K	0.628	0.29
75_I	79_A	0.627	0.29
61_A	82_L	0.627	0.29
154_K	297_K	0.626	0.29
256_V	266_V	0.626	0.29
382_R	464_T	0.626	0.29
41_V	404_E	0.625	0.29
465_T	469_K	0.625	0.29
375_N	434_D	0.624	0.29
239_L	251_T	0.624	0.29
344_M	449_N	0.624	0.29
70_V	133_L	0.624	0.29
154_K	258_D	0.624	0.29
41_V	367_G	0.623	0.29
270_L	280_L	0.623	0.29
242_P	279_S	0.623	0.29
116_L	243_G	0.622	0.28
429_L	441_A	0.621	0.28
364_R	369_R	0.620	0.28
225_L	288_N	0.620	0.28
54_A	119_L	0.619	0.28
416_T	441_A	0.618	0.28
363_A	370_L	0.618	0.28
217_M	243_G	0.617	0.28
267_I	364_R	0.615	0.28
210_E	214_E	0.614	0.28
376_S	424_I	0.610	0.28
249_M	313_R	0.610	0.28
16_V	161_Q	0.610	0.28
150_S	186_Y	0.608	0.28
310_N	337_K	0.606	0.27
179_K	297_K	0.605	0.27
186_Y	259_V	0.605	0.27
251_T	291_A	0.605	0.27
376_S	404_E	0.605	0.27
353_H	384_K	0.604	0.27
55_N	300_T	0.603	0.27
332_V	424_I	0.603	0.27
74_G	307_E	0.603	0.27
96_V	136_R	0.603	0.27
56_V	229_L	0.602	0.27
257_Y	283_A	0.600	0.27
159_S	327_E	0.600	0.27
33_S	258_D	0.600	0.27
391_N	468_I	0.600	0.27
216_G	391_N	0.598	0.27
307_E	311_A	0.598	0.27
298_L	376_S	0.598	0.27
327_E	330_L	0.596	0.27
322_V	401_G	0.595	0.27
440_I	445_E	0.595	0.27
172_V	301_S	0.594	0.27
460_D	465_T	0.594	0.27
191_L	227_A	0.594	0.27
25_W	107_L	0.592	0.27
366_L	468_I	0.592	0.27
115_Q	259_V	0.591	0.27
32_I	38_V	0.590	0.26
454_L	457_N	0.590	0.26
67_A	424_I	0.590	0.26
104_I	411_S	0.589	0.26
357_V	390_V	0.588	0.26
214_E	327_E	0.588	0.26
221_A	242_P	0.588	0.26
122_E	237_M	0.588	0.26
86_L	433_G	0.587	0.26
324_T	332_V	0.587	0.26
386_D	464_T	0.585	0.26
35_E	63_L	0.585	0.26
190_T	421_I	0.584	0.26
288_N	292_G	0.583	0.26
184_E	222_D	0.582	0.26
189_A	256_V	0.582	0.26
173_P	226_S	0.580	0.26
123_E	233_S	0.576	0.26
79_A	149_L	0.575	0.26
357_V	405_A	0.574	0.26
79_A	220_I	0.574	0.26
102_P	251_T	0.574	0.26
328_L	424_I	0.573	0.25
131_Q	135_E	0.573	0.25
251_T	361_A	0.573	0.25
304_S	327_E	0.572	0.25
24_Y	179_K	0.572	0.25
188_G	258_D	0.572	0.25
20_M	288_N	0.572	0.25
178_P	186_Y	0.571	0.25
216_G	220_I	0.570	0.25
73_T	286_F	0.570	0.25
174_V	409_V	0.570	0.25
61_A	339_G	0.570	0.25
122_E	266_V	0.569	0.25
367_G	433_G	0.569	0.25
390_V	398_I	0.569	0.25
148_V	257_Y	0.569	0.25
115_Q	154_K	0.569	0.25
444_K	448_A	0.568	0.25
33_S	444_K	0.568	0.25
171_G	214_E	0.568	0.25
141_L	381_K	0.567	0.25
156_A	345_T	0.567	0.25
15_V	67_A	0.566	0.25
164_I	174_V	0.565	0.25
308_L	311_A	0.564	0.25
265_T	290_A	0.564	0.25
129_D	132_P	0.564	0.25
214_E	413_E	0.564	0.25
354_A	459_E	0.563	0.25
111_S	292_G	0.562	0.25
119_L	381_K	0.561	0.25
15_V	60_I	0.560	0.25
84_K	128_V	0.560	0.25
217_M	324_T	0.560	0.25
111_S	199_F	0.559	0.25
260_T	408_W	0.559	0.25
277_G	339_G	0.558	0.25
115_Q	260_T	0.558	0.25
346_N	373_A	0.557	0.25
211_E	220_I	0.557	0.25
193_T	202_V	0.557	0.25
420_L	470_K	0.556	0.24
40_V	54_A	0.556	0.24
363_A	417_P	0.555	0.24
160_V	164_I	0.555	0.24
111_S	116_L	0.555	0.24
329_K	332_V	0.555	0.24
16_V	214_E	0.554	0.24
23_R	39_P	0.554	0.24
254_Q	296_G	0.553	0.24
459_E	462_C	0.553	0.24
13_V	60_I	0.553	0.24
267_I	408_W	0.551	0.24
57_A	153_A	0.551	0.24
160_V	166_L	0.551	0.24
66_N	181_T	0.550	0.24
193_T	291_A	0.550	0.24
371_I	457_N	0.549	0.24
145_G	173_P	0.549	0.24
392_P	465_T	0.548	0.24
168_R	382_R	0.548	0.24
243_G	306_I	0.548	0.24
182_D	186_Y	0.547	0.24
146_A	172_V	0.547	0.24
344_M	421_I	0.546	0.24
109_V	378_A	0.545	0.24
147_L	457_N	0.545	0.24
149_L	174_V	0.545	0.24
141_L	306_I	0.545	0.24
255_E	415_D	0.545	0.24
300_T	308_L	0.545	0.24
53_A	57_A	0.539	0.24
179_K	233_S	0.538	0.23
418_Q	421_I	0.538	0.23
68_R	145_G	0.537	0.23
71_G	82_L	0.536	0.23
154_K	442_G	0.536	0.23
34_P	253_A	0.535	0.23
29_T	335_A	0.535	0.23
38_V	82_L	0.535	0.23
54_A	91_V	0.535	0.23
202_V	397_M	0.533	0.23
275_A	445_E	0.532	0.23
72_L	100_T	0.532	0.23
24_Y	340_E	0.532	0.23
104_I	470_K	0.530	0.23
327_E	469_K	0.529	0.23
332_V	386_D	0.529	0.23
56_V	60_I	0.529	0.23
241_Q	247_L	0.529	0.23
62_S	303_V	0.528	0.23
203_V	408_W	0.528	0.23
401_G	420_L	0.528	0.23
325_E	329_K	0.527	0.23
398_I	402_A	0.527	0.23
250_P	285_F	0.527	0.23
33_S	154_K	0.525	0.23
179_K	288_N	0.525	0.23
59_N	294_V	0.525	0.23
358_S	456_L	0.524	0.23
186_Y	257_Y	0.524	0.23
259_V	265_T	0.523	0.23
66_N	394_E	0.522	0.23
266_V	440_I	0.522	0.23
395_Q	402_A	0.521	0.23
164_I	168_R	0.520	0.22
252_Q	341_K	0.519	0.22
34_P	429_L	0.518	0.22
104_I	123_E	0.517	0.22
180_G	294_V	0.516	0.22
56_V	148_V	0.515	0.22
78_A	387_S	0.514	0.22
233_S	302_T	0.513	0.22
363_A	375_N	0.512	0.22
283_A	331_A	0.512	0.22
87_A	341_K	0.512	0.22
56_V	59_N	0.511	0.22
59_N	259_V	0.510	0.22
364_R	368_D	0.510	0.22
150_S	234_E	0.510	0.22
154_K	266_V	0.510	0.22
149_L	222_D	0.509	0.22
417_P	464_T	0.509	0.22
143_S	241_Q	0.508	0.22
348_V	353_H	0.507	0.22
328_L	359_Y	0.507	0.22
230_V	380_T	0.507	0.22
191_L	270_L	0.507	0.22
268_G	295_V	0.506	0.22
168_R	224_E	0.505	0.22
336_R	404_E	0.505	0.22
199_F	228_L	0.505	0.22
217_M	306_I	0.504	0.22
68_R	140_A	0.503	0.22
113_N	130_P	0.503	0.22
90_N	310_N	0.503	0.22
207_K	279_S	0.502	0.22
90_N	390_V	0.502	0.22
163_M	187_R	0.502	0.22
50_P	58_M	0.502	0.22
154_K	429_L	0.501	0.21
354_A	392_P	0.501	0.21
268_G	402_A	0.500	0.21
203_V	216_G	0.500	0.21

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4e84A	2	0.6478	100	0.73	Contact Map
3vasA	1	0.631	100	0.772	Contact Map
4k8kA	2	0.6247	100	0.776	Contact Map
3looA	1	0.6268	100	0.777	Contact Map
2rbcA	2	0.6164	100	0.779	Contact Map
1bx4A	1	0.6268	100	0.779	Contact Map
2qcvA	3	0.6352	100	0.779	Contact Map
2jg1A	2	0.6457	100	0.78	Contact Map
2fv7A	2	0.6143	100	0.781	Contact Map
2ajrA	2	0.6373	100	0.783	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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