GREMLIN Database
PKA - Protein lysine acetyltransferase Pka
UniProt: P76594 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14224
Length: 886 (686)
Sequences: 1921 (1423)
Seq/√Len: 54.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
542_L548_V5.0051.00
290_R365_D4.7081.00
501_W515_Q4.6621.00
62_D65_S4.6621.00
587_V660_V4.2321.00
61_P65_S4.1641.00
675_I678_L4.0631.00
493_Y666_D4.0251.00
252_D266_R4.0171.00
90_G117_H3.6671.00
66_L70_P3.5651.00
589_V664_I3.5351.00
489_I692_L3.5261.00
120_R185_D3.3731.00
522_L573_V3.2051.00
87_E109_D3.0951.00
77_T85_L3.0481.00
149_K202_S3.0101.00
539_M554_A2.9581.00
506_S553_N2.9431.00
288_G365_D2.9061.00
656_L678_L2.8691.00
64_A88_E2.8591.00
47_V66_L2.8231.00
505_D552_A2.7661.00
601_L633_G2.7391.00
520_V573_V2.7051.00
617_A629_L2.6801.00
495_M687_A2.6751.00
514_E545_A2.6551.00
510_V548_V2.6381.00
542_L551_A2.6271.00
77_T81_R2.6021.00
499_P575_S2.5811.00
679_L688_L2.5591.00
507_T549_Q2.5221.00
256_D266_R2.5061.00
528_D567_R2.5011.00
87_E116_R2.4671.00
89_L94_C2.4321.00
75_L85_L2.3991.00
535_V559_V2.3981.00
521_A540_L2.3901.00
87_E91_E2.3711.00
322_T361_S2.3521.00
255_W259_I2.3491.00
505_D508_E2.2981.00
478_A485_E2.2861.00
319_S363_D2.2831.00
617_A632_Q2.2721.00
8_A95_K2.2521.00
585_L653_L2.2471.00
552_A571_L2.2461.00
73_A89_L2.2101.00
325_K360_H2.1801.00
555_I559_V2.1781.00
503_A512_I2.1081.00
254_A598_L2.1061.00
621_L657_L2.0991.00
86_L113_C2.0941.00
15_I136_L2.0911.00
73_A94_C2.0761.00
675_I687_A2.0731.00
64_A91_E2.0681.00
18_I73_A2.0641.00
86_L97_C2.0561.00
610_P642_R2.0331.00
600_M616_V2.0221.00
655_Q659_Q2.0171.00
99_I110_L2.0031.00
31_M100_L2.0021.00
108_E112_A2.0021.00
51_W59_A1.9961.00
261_R617_A1.9811.00
631_I650_V1.9731.00
601_L630_V1.9731.00
501_W512_I1.9631.00
483_T487_Q1.9461.00
623_M655_Q1.9431.00
387_I417_L1.9431.00
198_D201_T1.9421.00
316_A364_F1.9371.00
45_L60_W1.9211.00
528_D566_A1.9171.00
506_S510_V1.9161.00
603_E635_K1.9081.00
151_A175_S1.9061.00
22_M51_W1.9011.00
221_A264_L1.8830.99
295_S301_A1.8810.99
510_V549_Q1.8810.99
79_A101_S1.8750.99
518_Y548_V1.8730.99
355_L367_L1.8710.99
275_S431_G1.8510.99
63_I89_L1.8480.99
122_L129_L1.8430.99
23_K26_R1.8420.99
630_V654_S1.8400.99
509_A548_V1.8310.99
53_A56_G1.8290.99
60_W67_P1.8270.99
221_A230_I1.8230.99
289_D444_R1.8130.99
87_E113_C1.8030.99
545_A549_Q1.7950.99
289_D314_K1.7850.99
509_A513_A1.7840.99
518_Y544_T1.7810.99
384_Q388_E1.7790.99
504_S508_E1.7790.99
84_A88_E1.7750.99
175_S201_T1.7580.99
43_P68_F1.7520.99
555_I558_R1.7510.99
524_L529_I1.7390.99
521_A576_M1.7350.99
178_I195_L1.7240.99
69_T92_K1.7210.99
292_M364_F1.7170.99
114_A121_L1.7000.99
539_M551_A1.6900.99
660_V673_L1.6840.99
330_L334_V1.6670.99
552_A556_F1.6590.99
615_V629_L1.6540.99
502_I525_R1.6520.99
487_Q500_T1.6320.98
482_D485_E1.6280.98
18_I63_I1.6220.98
186_I191_L1.6140.98
66_L69_T1.6130.98
86_L119_M1.6070.98
526_S529_I1.6050.98
544_T547_E1.6040.98
319_S361_S1.5900.98
356_D392_H1.5870.98
259_I264_L1.5830.98
599_I619_P1.5780.98
678_L687_A1.5770.98
543_R547_E1.5750.98
267_V276_A1.5720.98
327_R336_I1.5710.98
513_A517_G1.5640.98
585_L680_A1.5620.98
663_L667_C1.5530.98
535_V562_A1.5480.98
205_L277_V1.5480.98
654_S658_V1.5180.98
416_R420_E1.5130.97
245_L302_A1.5100.97
36_L57_V1.4990.97
539_M558_R1.4970.97
62_D88_E1.4920.97
333_H343_R1.4860.97
630_V653_L1.4840.97
231_L280_L1.4800.97
631_I636_S1.4740.97
586_R600_M1.4730.97
291_L436_F1.4680.97
272_E434_T1.4600.97
90_G113_C1.4590.97
213_D216_R1.4590.97
378_P381_E1.4480.97
516_I575_S1.4460.97
667_C670_I1.4440.97
109_D112_A1.4360.97
248_T608_W1.4280.96
514_E518_Y1.4270.96
626_A657_L1.4210.96
17_V32_M1.4200.96
627_R654_S1.4070.96
46_P57_V1.4030.96
652_G684_E1.4000.96
656_L685_F1.3960.96
672_R693_D1.3750.96
204_I224_A1.3690.95
72_L138_A1.3580.95
151_A201_T1.3540.95
619_P661_S1.3500.95
22_M54_V1.3490.95
206_L232_V1.3410.95
627_R651_A1.3400.95
448_Q628_Y1.3390.95
510_V545_A1.3370.95
539_M555_I1.3330.95
530_P691_T1.3310.95
356_D360_H1.3300.95
294_I358_L1.3290.95
352_I388_E1.3280.95
513_A520_V1.3240.95
151_A195_L1.3230.95
553_N557_D1.3220.94
160_S177_F1.3190.94
83_L109_D1.3130.94
649_D684_E1.3060.94
33_R37_A1.3030.94
656_L675_I1.3000.94
524_L537_G1.2940.94
190_E216_R1.2930.94
648_L680_A1.2910.94
509_A517_G1.2860.94
279_T435_A1.2860.94
325_K357_I1.2830.94
522_L552_A1.2770.93
84_A87_E1.2710.93
551_A555_I1.2700.93
218_V258_A1.2640.93
542_L547_E1.2540.93
545_A548_V1.2530.93
97_C114_A1.2530.93
522_L571_L1.2460.93
112_A116_R1.2450.93
35_L44_V1.2440.92
107_H184_L1.2420.92
152_F174_F1.2380.92
66_L92_K1.2350.92
22_M53_A1.2320.92
403_T425_T1.2310.92
63_I92_K1.2300.92
359_L367_L1.2290.92
663_L670_I1.2250.92
518_Y545_A1.2240.92
247_T298_A1.2230.92
196_A224_A1.2220.92
9_L96_T1.2210.92
345_D350_H1.2200.92
261_R625_L1.2180.92
54_V59_A1.2140.92
630_V633_G1.2120.91
441_E444_R1.2050.91
234_K266_R1.2040.91
588_V674_D1.2040.91
189_D220_A1.2030.91
466_A489_I1.2020.91
63_I73_A1.1950.91
308_L313_G1.1910.91
75_L82_N1.1900.91
513_A518_Y1.1880.91
555_I571_L1.1870.91
52_K61_P1.1860.91
289_D440_V1.1790.90
260_Q632_Q1.1780.90
506_S552_A1.1770.90
96_T122_L1.1770.90
237_R310_S1.1760.90
67_P92_K1.1740.90
467_H669_E1.1720.90
292_M358_L1.1710.90
318_L364_F1.1700.90
633_G637_K1.1700.90
462_N465_E1.1690.90
649_D652_G1.1690.90
320_E324_Q1.1670.90
636_S650_V1.1670.90
522_L548_V1.1630.90
623_M658_V1.1570.89
589_V660_V1.1560.89
27_A140_F1.1550.89
325_K328_D1.1550.89
324_Q328_D1.1540.89
83_L90_G1.1520.89
626_A658_V1.1520.89
252_D256_D1.1510.89
16_A46_P1.1460.89
381_E384_Q1.1440.89
122_L186_I1.1420.89
322_T362_Q1.1420.89
586_R608_W1.1370.89
510_V518_Y1.1360.89
506_S549_Q1.1350.89
534_E643_S1.1340.88
554_A558_R1.1310.88
319_S322_T1.1300.88
196_A230_I1.1290.88
327_R334_V1.1290.88
524_L568_V1.1270.88
246_N672_R1.1270.88
150_L203_A1.1240.88
623_M654_S1.1190.88
46_P59_A1.1190.88
9_L122_L1.1180.88
29_Y33_R1.1140.88
442_Y446_Q1.1100.87
506_S548_V1.1090.87
366_A436_F1.1000.87
208_L232_V1.0950.87
585_L633_G1.0930.87
556_F571_L1.0900.86
524_L559_V1.0890.86
559_V571_L1.0820.86
384_Q417_L1.0790.86
329_A357_I1.0790.86
67_P70_P1.0740.86
607_E642_R1.0740.86
489_I492_A1.0740.86
374_S377_A1.0670.85
20_A28_G1.0640.85
7_E11_R1.0640.85
261_R618_L1.0640.85
470_L474_I1.0590.85
193_D223_S1.0560.85
230_I264_L1.0510.84
324_Q327_R1.0500.84
490_L690_V1.0490.84
269_D430_E1.0470.84
237_R252_D1.0410.84
629_L632_Q1.0410.84
279_T439_M1.0350.83
550_Q554_A1.0320.83
68_F92_K1.0320.83
486_V692_L1.0260.83
17_V46_P1.0240.83
526_S568_V1.0220.83
368_M432_T1.0220.83
334_V343_R1.0220.83
70_P94_C1.0200.83
483_T486_V1.0200.83
304_A368_M1.0190.82
500_T574_Q1.0160.82
613_Q634_I1.0160.82
268_Q310_S1.0140.82
159_V270_T1.0110.82
261_R632_Q1.0110.82
317_T320_E1.0110.82
465_E488_P1.0110.82
622_N625_L1.0080.82
583_Q645_L1.0070.82
320_E323_C1.0030.81
234_K252_D1.0000.81
493_Y667_C0.9960.81
318_L358_L0.9950.81
552_A555_I0.9930.81
242_Q245_L0.9930.81
349_E353_K0.9910.81
532_K689_D0.9900.81
670_I673_L0.9880.80
231_L267_V0.9870.80
32_M46_P0.9860.80
291_L308_L0.9830.80
353_K356_D0.9820.80
294_I354_T0.9820.80
300_P406_C0.9810.80
535_V558_R0.9750.80
232_V264_L0.9750.80
630_V636_S0.9730.79
311_R437_M0.9720.79
107_H182_D0.9680.79
176_Y195_L0.9670.79
81_R85_L0.9630.79
585_L678_L0.9600.78
531_H676_H0.9600.78
104_A182_D0.9600.78
361_S399_V0.9590.78
664_I670_I0.9570.78
102_A343_R0.9570.78
18_I89_L0.9560.78
22_M55_L0.9550.78
466_A470_L0.9520.78
192_L204_I0.9510.78
583_Q641_A0.9500.78
521_A577_A0.9490.78
52_K59_A0.9480.78
244_L298_A0.9470.78
10_L194_Y0.9470.78
6_L10_L0.9440.77
40_F43_P0.9440.77
626_A661_S0.9440.77
510_V520_V0.9420.77
26_R29_Y0.9420.77
601_L680_A0.9400.77
49_P59_A0.9380.77
519_P548_V0.9370.77
451_E622_N0.9360.77
241_A298_A0.9320.76
621_L626_A0.9310.76
106_Q182_D0.9300.76
90_G119_M0.9290.76
680_A683_S0.9290.76
196_A220_A0.9290.76
520_V548_V0.9260.76
20_A46_P0.9260.76
20_A54_V0.9240.76
386_L401_L0.9200.75
63_I66_L0.9200.75
148_G173_G0.9180.75
355_L389_A0.9160.75
326_L354_T0.9150.75
517_G520_V0.9140.75
9_L129_L0.9130.75
380_T417_L0.9120.75
509_A520_V0.9110.75
11_R194_Y0.9100.75
582_A688_L0.9090.75
636_S640_R0.9090.75
577_A686_T0.9080.74
481_L692_L0.9060.74
519_P544_T0.9050.74
258_A618_L0.9040.74
232_V259_I0.9030.74
122_L191_L0.8990.74
531_H604_G0.8980.74
495_M656_L0.8960.74
66_L89_L0.8950.73
358_L361_S0.8920.73
522_L551_A0.8920.73
149_K281_S0.8900.73
245_L298_A0.8900.73
29_Y55_L0.8890.73
480_S693_D0.8870.73
201_T228_K0.8840.72
183_S212_S0.8840.72
32_M57_V0.8810.72
585_L630_V0.8800.72
126_S179_A0.8790.72
531_H643_S0.8770.72
670_I692_L0.8770.72
437_M441_E0.8770.72
79_A104_A0.8730.72
290_R314_K0.8720.71
39_G42_G0.8720.71
472_Q476_E0.8720.71
37_A85_L0.8710.71
188_V208_L0.8710.71
609_R643_S0.8700.71
461_S494_G0.8690.71
615_V632_Q0.8690.71
524_L555_I0.8690.71
319_S362_Q0.8690.71
87_E117_H0.8690.71
45_L68_F0.8680.71
285_P443_R0.8670.71
559_V563_W0.8650.71
513_A548_V0.8650.71
45_L67_P0.8640.71
48_T78_N0.8640.71
48_T51_W0.8640.71
613_Q633_G0.8630.71
152_F163_I0.8620.71
167_A174_F0.8600.70
355_L386_L0.8580.70
599_I621_L0.8580.70
579_R582_A0.8580.70
247_T609_R0.8570.70
583_Q648_L0.8570.70
164_L177_F0.8570.70
83_L113_C0.8540.70
99_I114_A0.8540.70
85_L88_E0.8540.70
153_I195_L0.8530.70
146_K168_Q0.8510.70
82_N86_L0.8500.70
102_A158_A0.8490.69
346_A351_Y0.8450.69
597_P619_P0.8410.69
238_S241_A0.8400.69
318_L322_T0.8400.69
165_D407_G0.8400.69
462_N492_A0.8380.68
103_P106_Q0.8380.68
469_L473_A0.8370.68
13_K68_F0.8370.68
652_G685_F0.8360.68
55_L59_A0.8340.68
196_A223_S0.8330.68
556_F568_V0.8330.68
35_L71_D0.8330.68
529_I566_A0.8320.68
359_L399_V0.8320.68
604_G676_H0.8320.68
294_I355_L0.8310.68
250_G298_A0.8290.68
651_A654_S0.8280.67
271_H431_G0.8280.67
621_L629_L0.8260.67
359_L393_H0.8260.67
78_N81_R0.8250.67
31_M34_N0.8240.67
490_L663_L0.8220.67
14_S43_P0.8210.67
479_T485_E0.8210.67
211_L255_W0.8190.67
45_L66_L0.8180.67
588_V676_H0.8180.67
498_L577_A0.8180.67
133_W200_K0.8170.66
566_A570_G0.8140.66
617_A625_L0.8140.66
470_L667_C0.8130.66
291_L433_I0.8130.66
548_V552_A0.8090.66
64_A92_K0.8070.65
329_A353_K0.8070.65
46_P60_W0.8060.65
522_L555_I0.8060.65
587_V657_L0.8050.65
524_L564_P0.8020.65
76_C100_L0.8010.65
524_L528_D0.8010.65
207_Y244_L0.7990.65
322_T326_L0.7980.65
23_K29_Y0.7970.65
526_S566_A0.7970.65
626_A629_L0.7950.64
540_L576_M0.7950.64
533_S584_E0.7940.64
323_C336_I0.7940.64
21_S28_G0.7900.64
125_N140_F0.7900.64
247_T584_E0.7890.64
671_Q695_S0.7880.64
678_L685_F0.7870.64
544_T548_V0.7860.63
154_S207_Y0.7860.63
208_L212_S0.7860.63
125_N247_T0.7860.63
109_D113_C0.7860.63
238_S310_S0.7810.63
63_I85_L0.7810.63
587_V656_L0.7810.63
487_Q690_V0.7800.63
579_R681_S0.7800.63
193_D220_A0.7790.63
98_I129_L0.7780.63
192_L220_A0.7780.63
197_R223_S0.7780.63
359_L401_L0.7750.62
27_A344_D0.7730.62
526_S570_G0.7730.62
558_R562_A0.7710.62
44_V57_V0.7700.62
527_P569_H0.7700.62
236_G250_G0.7680.62
532_K676_H0.7660.61
290_R316_A0.7650.61
217_F221_A0.7650.61
91_E116_R0.7640.61
248_T609_R0.7630.61
183_S188_V0.7620.61
53_A58_L0.7620.61
111_R115_L0.7610.61
520_V542_L0.7600.61
531_H609_R0.7590.61
413_E416_R0.7580.61
473_A492_A0.7560.60
244_L302_A0.7560.60
178_I191_L0.7500.60
96_T186_I0.7500.60
241_A244_L0.7490.60
53_A57_V0.7480.60
17_V31_M0.7480.60
608_W676_H0.7470.59
387_I421_A0.7460.59
533_S606_V0.7450.59
495_M659_Q0.7430.59
612_D637_K0.7420.59
609_R674_D0.7400.59
298_A341_D0.7400.59
599_I664_I0.7380.59
342_L354_T0.7380.59
15_I70_P0.7380.59
130_L139_S0.7370.58
512_I573_V0.7360.58
20_A48_T0.7350.58
125_N157_A0.7330.58
582_A679_L0.7320.58
247_T250_G0.7300.58
377_A411_S0.7270.57
36_L55_L0.7270.57
601_L629_L0.7250.57
511_H514_E0.7240.57
507_T510_V0.7240.57
524_L566_A0.7220.57
531_H608_W0.7210.57
557_D561_M0.7210.57
559_V568_V0.7170.56
524_L535_V0.7150.56
170_R278_E0.7140.56
402_L436_F0.7120.56
8_A71_D0.7120.56
249_A616_V0.7120.56
173_G185_D0.7120.56
463_T467_H0.7110.56
380_T384_Q0.7100.56
174_F177_F0.7100.56
193_D222_R0.7090.56
532_K584_E0.7080.55
559_V564_P0.7080.55
510_V514_E0.7050.55
366_A400_S0.7040.55
620_P626_A0.7040.55
154_S160_S0.7040.55
621_L625_L0.7040.55
298_A302_A0.7030.55
175_S228_K0.7030.55
627_R631_I0.7030.55
408_E427_R0.7000.55
111_R184_L0.6970.54
335_A340_L0.6960.54
45_L89_L0.6950.54
584_E604_G0.6950.54
424_P508_E0.6940.54
16_A19_G0.6940.54
69_T94_C0.6940.54
160_S344_D0.6930.54
217_F264_L0.6930.54
278_E282_H0.6930.54
499_P515_Q0.6920.54
511_H545_A0.6920.54
126_S244_L0.6920.54
78_N101_S0.6910.54
495_M663_L0.6900.53
70_P92_K0.6900.53
244_L295_S0.6890.53
137_N296_N0.6890.53
110_L115_L0.6870.53
15_I40_F0.6870.53
51_W61_P0.6860.53
507_T545_A0.6860.53
82_N99_I0.6860.53
9_L522_L0.6850.53
86_L114_A0.6850.53
28_G76_C0.6840.53
187_D190_E0.6840.53
631_I640_R0.6830.53
244_L247_T0.6830.53
242_Q687_A0.6820.53
259_I618_L0.6820.53
158_A344_D0.6800.52
585_L601_L0.6790.52
577_A681_S0.6780.52
248_T588_V0.6760.52
152_F177_F0.6760.52
589_V673_L0.6750.52
660_V675_I0.6750.52
104_A107_H0.6740.52
241_A247_T0.6730.52
140_F331_P0.6710.51
15_I35_L0.6710.51
63_I88_E0.6700.51
152_F167_A0.6690.51
640_R650_V0.6680.51
629_L657_L0.6670.51
486_V690_V0.6670.51
35_L136_L0.6660.51
293_I315_L0.6660.51
529_I559_V0.6650.51
523_K584_E0.6650.51
103_P124_P0.6630.51
189_D196_A0.6620.51
45_L58_L0.6620.51
187_D213_D0.6610.50
380_T413_E0.6600.50
163_I291_L0.6600.50
512_I515_Q0.6590.50
8_A96_T0.6580.50
196_A204_I0.6580.50
598_L618_L0.6580.50
487_Q497_T0.6570.50
535_V555_I0.6560.50
272_E438_H0.6560.50
527_P566_A0.6560.50
236_G241_A0.6560.50
590_E674_D0.6550.50
663_L673_L0.6540.50
31_M76_C0.6540.50
267_V273_L0.6540.50
176_Y201_T0.6530.50
465_E468_L0.6530.50
321_E391_K0.6510.49
491_Q497_T0.6500.49
680_A684_E0.6490.49
21_S234_K0.6490.49
45_L70_P0.6480.49
246_N588_V0.6480.49
582_A682_G0.6470.49
588_V604_G0.6470.49
501_W516_I0.6460.49
79_A312_N0.6450.49
500_T572_L0.6450.49
601_L657_L0.6450.49
241_A245_L0.6450.49
296_N407_G0.6440.49
589_V670_I0.6430.48
331_P350_H0.6420.48
463_T667_C0.6410.48
647_P674_D0.6400.48
535_V563_W0.6390.48
193_D216_R0.6390.48
239_P309_W0.6390.48
196_A226_R0.6390.48
582_A681_S0.6350.48
321_E362_Q0.6340.48
559_V562_A0.6340.48
403_T418_F0.6340.48
260_Q441_E0.6330.47
189_D216_R0.6320.47
31_M74_V0.6320.47
292_M318_L0.6320.47
70_P85_L0.6320.47
140_F302_A0.6320.47
603_E611_E0.6320.47
174_F201_T0.6320.47
43_P58_L0.6310.47
489_I663_L0.6300.47
609_R691_T0.6290.47
537_G576_M0.6290.47
526_S569_H0.6290.47
79_A83_L0.6270.47
481_L485_E0.6270.47
291_L368_M0.6270.47
673_L678_L0.6250.47
145_I259_I0.6250.47
526_S535_V0.6250.47
466_A667_C0.6250.47
246_N606_V0.6250.47
211_L217_F0.6240.46
193_D219_S0.6240.46
648_L685_F0.6230.46
176_Y194_Y0.6220.46
224_A297_G0.6210.46
516_I520_V0.6210.46
662_N665_V0.6210.46
659_Q662_N0.6200.46
158_A296_N0.6200.46
48_T59_A0.6200.46
150_L277_V0.6190.46
298_A676_H0.6190.46
196_A228_K0.6180.46
556_F559_V0.6170.46
63_I94_C0.6170.46
524_L556_F0.6160.46
75_L86_L0.6160.46
247_T533_S0.6160.46
331_P343_R0.6160.46
24_P646_R0.6150.46
298_A643_S0.6140.45
18_I85_L0.6140.45
326_L330_L0.6130.45
321_E550_Q0.6130.45
44_V60_W0.6130.45
313_G437_M0.6120.45
527_P568_V0.6110.45
198_D228_K0.6110.45
70_P93_G0.6110.45
344_D350_H0.6110.45
508_E512_I0.6100.45
390_V401_L0.6100.45
240_A305_L0.6100.45
247_T676_H0.6100.45
511_H515_Q0.6100.45
681_S684_E0.6100.45
482_D569_H0.6100.45
131_A194_Y0.6090.45
157_A588_V0.6090.45
292_M367_L0.6080.45
533_S643_S0.6080.45
489_I670_I0.6060.45
494_G659_Q0.6060.45
483_T690_V0.6060.45
296_N373_P0.6050.44
114_A117_H0.6050.44
193_D196_A0.6050.44
534_E537_G0.6050.44
18_I92_K0.6050.44
177_F574_Q0.6050.44
284_R400_S0.6040.44
322_T358_L0.6040.44
463_T493_Y0.6030.44
488_P491_Q0.6030.44
99_I184_L0.6030.44
254_A595_F0.6020.44
352_I356_D0.6020.44
482_D525_R0.6010.44
417_L421_A0.6010.44
467_H470_L0.5990.44
115_L185_D0.5990.44
265_L442_Y0.5980.44
599_I629_L0.5970.44
157_A341_D0.5970.44
528_D556_F0.5970.44
292_M316_A0.5960.43
125_N298_A0.5950.43
125_N244_L0.5940.43
386_L389_A0.5940.43
90_G93_G0.5940.43
316_A354_T0.5940.43
110_L119_M0.5930.43
334_V340_L0.5930.43
47_V186_I0.5930.43
241_A302_A0.5930.43
250_G295_S0.5930.43
190_E273_L0.5910.43
125_N250_G0.5900.43
676_H689_D0.5890.43
203_A280_L0.5880.43
205_L274_F0.5870.43
71_D80_S0.5870.43
642_R645_L0.5850.42
102_A125_N0.5850.42
219_S625_L0.5850.42
246_N531_H0.5830.42
247_T588_V0.5820.42
167_A274_F0.5820.42
81_R84_A0.5820.42
192_L432_T0.5810.42
276_A438_H0.5800.42
638_K641_A0.5770.42
603_E633_G0.5770.42
563_W566_A0.5770.42
467_H471_Q0.5760.41
63_I67_P0.5760.41
45_L57_V0.5750.41
473_A485_E0.5750.41
451_E658_V0.5740.41
637_K642_R0.5740.41
498_L574_Q0.5740.41
642_R646_R0.5740.41
110_L121_L0.5740.41
507_T544_T0.5730.41
503_A508_E0.5730.41
587_V678_L0.5720.41
274_F296_N0.5720.41
243_R337_S0.5720.41
577_A678_L0.5720.41
86_L110_L0.5710.41
215_R219_S0.5710.41
528_D570_G0.5710.41
26_R31_M0.5700.41
16_A47_V0.5700.41
207_Y383_A0.5700.41
621_L661_S0.5700.41
279_T402_L0.5700.41
588_V608_W0.5700.41
564_P567_R0.5690.41
249_A600_M0.5690.41
246_N302_A0.5670.40
399_V692_L0.5670.40
47_V53_A0.5670.40
653_L680_A0.5670.40
88_E91_E0.5670.40
159_V303_L0.5660.40
131_A176_Y0.5660.40
11_R134_Q0.5650.40
46_P58_L0.5650.40
142_P634_I0.5650.40
497_T687_A0.5650.40
244_L301_A0.5650.40
577_A688_L0.5640.40
586_R641_A0.5640.40
273_L663_L0.5640.40
477_G682_G0.5640.40
10_L178_I0.5640.40
64_A67_P0.5620.40
321_E324_Q0.5620.40
74_V138_A0.5610.40
246_N249_A0.5600.40
623_M651_A0.5600.40
103_P247_T0.5590.40
35_L73_A0.5590.40
241_A250_G0.5570.39
195_L201_T0.5570.39
599_I665_V0.5570.39
87_E90_G0.5560.39
533_S689_D0.5560.39
527_P567_R0.5550.39
531_H689_D0.5530.39
247_T531_H0.5530.39
484_H488_P0.5530.39
241_A309_W0.5530.39
528_D568_V0.5510.39
487_Q574_Q0.5510.39
236_G306_D0.5510.39
454_A655_Q0.5500.39
41_N135_G0.5500.39
27_A127_L0.5490.39
109_D560_K0.5490.39
161_N372_S0.5490.39
322_T363_D0.5490.39
480_S530_P0.5480.39
241_A521_A0.5480.39
247_T674_D0.5470.38
157_A247_T0.5470.38
240_A247_T0.5470.38
466_A493_Y0.5470.38
362_Q399_V0.5460.38
247_T341_D0.5460.38
259_I366_A0.5460.38
503_A509_A0.5450.38
153_I675_I0.5450.38
125_N531_H0.5440.38
465_E492_A0.5420.38
225_S668_P0.5420.38
584_E676_H0.5410.38
258_A595_F0.5410.38
607_E610_P0.5410.38
83_L87_E0.5410.38
89_L185_D0.5400.38
248_T586_R0.5400.38
18_I75_L0.5400.38
551_A626_A0.5380.38
601_L635_K0.5380.38
216_R219_S0.5380.38
323_C334_V0.5370.37
526_S559_V0.5370.37
523_K643_S0.5360.37
45_L48_T0.5360.37
564_P568_V0.5360.37
640_R647_P0.5360.37
674_D692_L0.5360.37
560_K566_A0.5350.37
269_D272_E0.5350.37
19_G28_G0.5350.37
221_A308_L0.5350.37
556_F564_P0.5350.37
75_L89_L0.5340.37
247_T643_S0.5340.37
291_L432_T0.5340.37
83_L86_L0.5340.37
17_V207_Y0.5330.37
151_A636_S0.5330.37
507_T546_N0.5330.37
544_T550_Q0.5330.37
494_G545_A0.5330.37
110_L545_A0.5320.37
17_V521_A0.5320.37
14_S470_L0.5320.37
637_K640_R0.5320.37
154_S158_A0.5310.37
248_T600_M0.5310.37
318_L440_V0.5310.37
269_D377_A0.5300.37
14_S45_L0.5300.37
96_T129_L0.5290.37
187_D195_L0.5290.37
523_K532_K0.5290.37
445_N448_Q0.5290.37
93_G290_R0.5280.37
210_Q255_W0.5280.37
656_L687_A0.5280.37
86_L121_L0.5270.36
591_H671_Q0.5270.36
28_G48_T0.5270.36
582_A684_E0.5270.36
341_D531_H0.5270.36
95_K111_R0.5260.36
403_T423_L0.5250.36
619_P665_V0.5250.36
371_H574_Q0.5240.36
111_R568_V0.5240.36
661_S664_I0.5240.36
82_N102_A0.5240.36
313_G436_F0.5230.36
298_A584_E0.5230.36
560_K565_Q0.5230.36
427_R431_G0.5220.36
470_L473_A0.5220.36
575_S686_T0.5220.36
585_L648_L0.5220.36
384_Q656_L0.5220.36
20_A26_R0.5210.36
254_A258_A0.5210.36
236_G247_T0.5210.36
30_L34_N0.5210.36
125_N341_D0.5210.36
454_A662_N0.5200.36
28_G34_N0.5200.36
298_A532_K0.5180.36
18_I77_T0.5180.36
178_I243_R0.5180.36
47_V63_I0.5150.35
140_F158_A0.5150.35
67_P593_P0.5150.35
260_Q367_L0.5150.35
510_V659_Q0.5150.35
311_R434_T0.5140.35
216_R230_I0.5130.35
328_D353_K0.5120.35
111_R118_N0.5120.35
9_L555_I0.5120.35
346_A350_H0.5120.35
368_M436_F0.5120.35
103_P244_L0.5110.35
547_E551_A0.5110.35
116_R420_E0.5110.35
326_L358_L0.5110.35
463_T666_D0.5110.35
82_N125_N0.5100.35
383_A405_W0.5100.35
79_A94_C0.5100.35
129_L178_I0.5100.35
600_M674_D0.5100.35
518_Y542_L0.5090.35
514_E544_T0.5090.35
153_I568_V0.5090.35
113_C119_M0.5090.35
106_Q125_N0.5090.35
297_G376_A0.5090.35
619_P674_D0.5080.35
482_D692_L0.5080.35
83_L110_L0.5070.34
28_G296_N0.5070.34
151_A176_Y0.5070.34
313_G365_D0.5070.34
493_Y663_L0.5060.34
47_V60_W0.5050.34
127_L167_A0.5050.34
506_S509_A0.5050.34
523_K531_H0.5050.34
599_I661_S0.5040.34
402_L576_M0.5040.34
304_A432_T0.5040.34
180_L191_L0.5040.34
526_S537_G0.5040.34
58_L66_L0.5030.34
556_F560_K0.5030.34
261_R313_G0.5030.34
27_A162_T0.5020.34
358_L367_L0.5020.34
247_T299_A0.5020.34
45_L94_C0.5010.34
484_H525_R0.5010.34
323_C337_S0.5010.34
203_A436_F0.5010.34
507_T511_H0.5010.34
604_G689_D0.5000.34
388_E392_H0.5000.34
532_K604_G0.5000.34
96_T180_L0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2csuA 2 0.4786 100 0.628 Contact Map
3dmyA 2 0.4616 100 0.693 Contact Map
3pffA 2 0.3059 100 0.777 Contact Map
3mwdB 1 0.316 100 0.785 Contact Map
2yv1A 1 0.2912 100 0.804 Contact Map
2fp4A 1 0.3183 100 0.807 Contact Map
2nu8A 1 0.3002 100 0.809 Contact Map
2yv2A 1 0.2912 100 0.811 Contact Map
1oi7A 1 0.2912 100 0.813 Contact Map
1wr2A 1 0.2619 100 0.861 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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