YFHM - ECOLI - GREMLIN Contacts

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YFHM - Uncharacterized lipoprotein YfhM

UniProt:	P76578	Sequences: MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSENASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIHVVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTITTRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRNSLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAGRYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQATSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFGPRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTWPLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSVVGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDKGRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWWQEIDVRAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDENRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVVQQALPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRFMASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAIPADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNSDERIWLGDYGSSLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAARTIQDLPGKWQAQTSFSAEQLTGEKAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYPQSAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLPAGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPVTLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13394
Length:	1653 (1495)
Sequences:	1414 (1160)
Seq/√Len:	30.0

ECOLI - YFHM YFAS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
292_I	316_Q	7.999	1.00
316_Q	319_I	7.897	1.00
292_I	307_T	7.812	1.00
307_T	316_Q	5.932	1.00
774_K	811_T	5.645	1.00
407_G	446_Y	5.644	1.00
510_G	592_L	5.503	1.00
564_D	568_R	5.489	1.00
334_A	342_V	5.366	1.00
654_D	658_V	5.287	1.00
319_I	355_A	5.240	1.00
1549_D	1614_Y	5.152	1.00
978_N	982_E	5.145	1.00
1187_C	1190_Q	5.109	1.00
874_P	986_T	5.064	1.00
913_D	916_Q	5.036	1.00
764_K	771_D	4.994	1.00
880_K	982_E	4.920	1.00
1036_T	1088_R	4.900	1.00
876_T	986_T	4.879	1.00
737_F	740_G	4.860	1.00
763_D	767_Y	4.858	1.00
1378_W	1381_D	4.856	1.00
1185_Y	1601_A	4.843	1.00
1258_M	1279_G	4.822	1.00
1188_L	1233_M	4.763	1.00
1623_T	1647_D	4.419	1.00
975_V	983_G	4.373	1.00
404_I	449_T	4.287	1.00
1513_G	1517_K	4.276	1.00
1237_N	1249_E	4.240	1.00
1183_Y	1187_C	4.221	1.00
103_V	137_V	4.190	1.00
403_V	477_F	4.097	1.00
737_F	741_Y	4.053	1.00
878_K	982_E	4.052	1.00
815_D	818_W	3.998	1.00
1195_L	1226_G	3.859	1.00
1187_C	1634_M	3.823	1.00
1187_C	1425_T	3.736	1.00
878_K	984_S	3.521	1.00
1530_V	1616_A	3.520	1.00
307_T	319_I	3.501	1.00
321_V	342_V	3.467	1.00
1136_T	1486_L	3.459	1.00
874_P	988_P	3.427	1.00
294_V	307_T	3.387	1.00
1554_G	1618_A	3.370	1.00
1183_Y	1190_Q	3.351	1.00
307_T	321_V	3.323	1.00
1183_Y	1425_T	3.307	1.00
1183_Y	1189_E	3.250	1.00
1190_Q	1425_T	3.247	1.00
489_L	592_L	3.243	1.00
1190_Q	1634_M	3.200	1.00
772_T	811_T	3.199	1.00
1532_V	1614_Y	3.185	1.00
405_L	463_I	3.183	1.00
1029_R	1595_D	3.182	1.00
859_L	881_A	3.178	1.00
1163_L	1488_M	3.125	1.00
896_V	998_V	3.081	1.00
1189_E	1425_T	3.065	1.00
1183_Y	1634_M	3.047	1.00
784_K	802_D	3.045	1.00
1099_Q	1118_Q	3.044	1.00
1623_T	1649_L	3.041	1.00
291_D	309_S	3.013	1.00
1387_R	1426_Q	2.993	1.00
667_V	700_Q	2.938	1.00
1053_L	1073_V	2.912	1.00
1425_T	1634_M	2.910	1.00
876_T	984_S	2.870	1.00
669_L	723_L	2.784	1.00
901_S	997_R	2.769	1.00
199_F	270_A	2.738	1.00
405_L	448_F	2.726	1.00
947_F	950_D	2.724	1.00
320_E	333_Q	2.721	1.00
350_A	355_A	2.712	1.00
1191_T	1233_M	2.675	1.00
741_Y	745_D	2.671	1.00
665_L	725_V	2.668	1.00
398_R	1595_D	2.662	1.00
1023_A	1100_A	2.661	1.00
1314_L	1318_R	2.659	1.00
1029_R	1556_E	2.657	1.00
865_T	998_V	2.629	1.00
773_I	813_P	2.626	1.00
1629_P	1643_G	2.625	1.00
995_E	1014_K	2.613	1.00
513_L	905_N	2.600	1.00
1036_T	1086_P	2.586	1.00
1185_Y	1189_E	2.585	1.00
1532_V	1549_D	2.584	1.00
425_D	433_V	2.565	0.99
1187_C	1635_Y	2.562	0.99
1188_L	1253_L	2.536	0.99
336_S	342_V	2.535	0.99
1188_L	1230_L	2.530	0.99
1189_E	1634_M	2.518	0.99
901_S	1014_K	2.514	0.99
1377_I	1381_D	2.486	0.99
1256_Y	1429_N	2.485	0.99
1555_L	1648_L	2.484	0.99
1524_L	1618_A	2.476	0.99
1184_P	1189_E	2.465	0.99
320_E	335_T	2.452	0.99
1227_I	1261_L	2.440	0.99
1191_T	1229_R	2.431	0.99
1508_E	1535_Q	2.416	0.99
427_I	464_R	2.411	0.99
764_K	767_Y	2.405	0.99
1184_P	1425_T	2.404	0.99
733_S	737_F	2.403	0.99
294_V	355_A	2.399	0.99
773_I	850_L	2.375	0.99
1185_Y	1190_Q	2.373	0.99
891_Q	976_T	2.372	0.99
388_F	409_L	2.370	0.99
785_G	827_T	2.368	0.99
665_L	702_L	2.365	0.99
296_A	364_L	2.362	0.99
1097_E	1118_Q	2.361	0.99
509_V	568_R	2.345	0.99
946_R	950_D	2.331	0.99
1547_V	1602_V	2.320	0.99
297_H	790_E	2.311	0.99
1555_L	1616_A	2.309	0.99
510_G	563_L	2.298	0.99
347_D	350_A	2.297	0.99
294_V	319_I	2.271	0.99
1259_D	1311_Y	2.255	0.99
544_F	616_G	2.254	0.99
1284_L	1321_K	2.250	0.99
1047_T	1077_P	2.242	0.99
527_L	588_F	2.231	0.99
1317_A	1352_T	2.213	0.98
1239_G	1249_E	2.204	0.98
1184_P	1187_C	2.204	0.98
530_R	587_I	2.187	0.98
1533_W	1613_V	2.185	0.98
732_V	737_F	2.185	0.98
1279_G	1283_L	2.168	0.98
896_V	987_L	2.159	0.98
1240_F	1279_G	2.156	0.98
187_V	195_V	2.155	0.98
1030_F	1553_A	2.143	0.98
349_N	354_L	2.138	0.98
1235_R	1249_E	2.127	0.98
403_V	452_L	2.125	0.98
1043_I	1073_V	2.122	0.98
773_I	814_V	2.111	0.98
542_F	649_D	2.110	0.98
734_S	740_G	2.099	0.98
1184_P	1190_Q	2.099	0.98
1535_Q	1611_T	2.097	0.98
1276_I	1279_G	2.096	0.98
1524_L	1555_L	2.091	0.98
1589_K	1603_A	2.090	0.98
996_L	1017_V	2.088	0.98
1556_E	1595_D	2.082	0.98
894_V	1000_A	2.080	0.98
349_N	355_A	2.061	0.98
441_P	893_N	2.055	0.98
433_V	436_S	2.052	0.97
526_Q	591_S	2.052	0.97
875_L	1015_V	2.050	0.97
883_T	887_E	2.038	0.97
1532_V	1616_A	2.038	0.97
1073_V	1083_L	2.032	0.97
1551_L	1616_A	2.032	0.97
136_I	158_T	2.030	0.97
864_E	878_K	2.019	0.97
393_P	969_V	2.017	0.97
1507_I	1547_V	2.011	0.97
426_V	452_L	2.011	0.97
1189_E	1193_S	2.008	0.97
1524_L	1530_V	1.999	0.97
734_S	737_F	1.997	0.97
666_Q	701_T	1.996	0.97
1185_Y	1425_T	1.991	0.97
1311_Y	1314_L	1.986	0.97
862_A	880_K	1.985	0.97
267_V	290_S	1.985	0.97
1076_A	1079_V	1.984	0.97
391_F	895_L	1.980	0.97
1188_L	1257_V	1.974	0.97
1605_D	1608_Q	1.970	0.97
309_S	312_N	1.964	0.97
1241_A	1247_G	1.960	0.97
1052_K	1074_E	1.957	0.97
774_K	809_D	1.955	0.97
428_K	432_Q	1.949	0.97
524_Q	591_S	1.946	0.97
427_I	462_H	1.944	0.96
350_A	353_L	1.929	0.96
1048_D	1077_P	1.924	0.96
406_N	893_N	1.922	0.96
1191_T	1226_G	1.915	0.96
860_D	882_S	1.914	0.96
732_V	740_G	1.912	0.96
1047_T	1078_G	1.905	0.96
668_R	724_E	1.903	0.96
1530_V	1555_L	1.894	0.96
141_K	154_D	1.891	0.96
665_L	704_L	1.889	0.96
270_A	287_F	1.888	0.96
507_S	570_E	1.883	0.96
1254_T	1279_G	1.880	0.96
879_I	894_V	1.876	0.96
741_Y	744_Q	1.875	0.96
1466_L	1471_L	1.873	0.96
733_S	740_G	1.867	0.96
787_A	801_I	1.862	0.96
1231_L	1275_A	1.857	0.95
1525_R	1528_D	1.856	0.95
1534_L	1549_D	1.843	0.95
869_M	989_I	1.841	0.95
355_A	789_V	1.839	0.95
489_L	510_G	1.833	0.95
666_Q	699_E	1.829	0.95
864_E	880_K	1.827	0.95
1057_L	1100_A	1.822	0.95
1384_S	1387_R	1.818	0.95
1314_L	1317_A	1.816	0.95
1241_A	1245_K	1.806	0.95
350_A	354_L	1.800	0.95
814_V	852_L	1.794	0.94
520_G	565_D	1.790	0.94
426_V	477_F	1.789	0.94
297_H	928_I	1.787	0.94
763_D	774_K	1.784	0.94
318_G	335_T	1.784	0.94
395_D	909_Y	1.782	0.94
480_E	1559_N	1.766	0.94
789_V	825_L	1.764	0.94
1547_V	1631_V	1.760	0.94
198_N	273_N	1.758	0.94
134_D	158_T	1.755	0.94
767_Y	771_D	1.746	0.94
877_V	896_V	1.743	0.94
740_G	744_Q	1.742	0.94
565_D	568_R	1.740	0.94
664_G	701_T	1.736	0.93
1509_R	1549_D	1.736	0.93
863_L	1011_N	1.729	0.93
1054_N	1072_A	1.724	0.93
1534_L	1614_Y	1.720	0.93
390_M	407_G	1.719	0.93
1519_K	1530_V	1.714	0.93
736_R	740_G	1.712	0.93
813_P	816_K	1.711	0.93
1064_E	1090_L	1.707	0.93
119_D	122_K	1.691	0.93
664_G	703_D	1.689	0.92
897_S	999_M	1.689	0.92
615_P	652_Y	1.689	0.92
1258_M	1276_I	1.689	0.92
1510_H	1535_Q	1.683	0.92
185_L	270_A	1.672	0.92
670_I	724_E	1.670	0.92
1265_G	1276_I	1.668	0.92
767_Y	773_I	1.661	0.92
869_M	875_L	1.659	0.92
786_Y	800_E	1.637	0.91
103_V	139_I	1.635	0.91
291_D	311_E	1.628	0.91
862_A	882_S	1.628	0.91
320_E	356_R	1.620	0.91
1339_S	1342_P	1.611	0.91
678_W	686_W	1.608	0.90
1556_E	1594_R	1.606	0.90
198_N	271_V	1.604	0.90
452_L	479_V	1.593	0.90
968_V	996_L	1.590	0.90
1065_L	1068_D	1.589	0.90
772_T	813_P	1.586	0.90
304_D	341_H	1.581	0.90
1523_S	1651_V	1.579	0.90
812_I	850_L	1.577	0.90
774_K	812_I	1.576	0.90
896_V	1000_A	1.573	0.89
736_R	739_A	1.571	0.89
1530_V	1650_I	1.570	0.89
1190_Q	1635_Y	1.570	0.89
1531_L	1615_L	1.569	0.89
1529_L	1617_R	1.561	0.89
1326_A	1330_I	1.561	0.89
1124_R	1596_D	1.560	0.89
870_R	873_Q	1.555	0.89
1004_T	1007_D	1.547	0.89
868_K	1018_A	1.540	0.88
1054_N	1070_P	1.539	0.88
85_L	137_V	1.537	0.88
513_L	902_G	1.537	0.88
356_R	359_G	1.534	0.88
899_V	904_L	1.531	0.88
1534_L	1629_P	1.519	0.88
1505_L	1631_V	1.513	0.88
1163_L	1449_T	1.513	0.88
1041_L	1055_V	1.510	0.87
865_T	1013_S	1.509	0.87
1537_K	1609_P	1.508	0.87
1186_G	1197_P	1.503	0.87
1043_I	1055_V	1.502	0.87
1311_Y	1316_L	1.500	0.87
1282_R	1286_Y	1.497	0.87
1180_L	1197_P	1.497	0.87
700_Q	712_V	1.489	0.87
1510_H	1533_W	1.477	0.86
704_L	710_G	1.476	0.86
678_W	683_D	1.473	0.86
1618_A	1650_I	1.467	0.86
1422_W	1428_S	1.466	0.86
1058_T	1099_Q	1.465	0.86
668_R	726_K	1.464	0.86
1193_S	1256_Y	1.462	0.86
1185_Y	1634_M	1.460	0.86
520_G	562_T	1.457	0.85
505_K	572_S	1.456	0.85
294_V	364_L	1.455	0.85
861_L	879_I	1.455	0.85
1230_L	1275_A	1.455	0.85
402_T	449_T	1.451	0.85
1165_L	1449_T	1.451	0.85
1545_A	1631_V	1.445	0.85
1280_N	1321_K	1.444	0.85
322_S	356_R	1.444	0.85
452_L	1449_T	1.441	0.85
197_V	254_L	1.440	0.85
790_E	926_A	1.437	0.85
645_N	713_S	1.436	0.85
105_D	135_L	1.434	0.85
995_E	1016_I	1.432	0.84
670_I	696_I	1.430	0.84
1050_P	1076_A	1.430	0.84
962_V	965_V	1.429	0.84
187_V	1650_I	1.428	0.84
647_A	711_K	1.426	0.84
102_H	140_G	1.423	0.84
169_G	188_M	1.423	0.84
460_M	478_H	1.417	0.84
487_M	521_N	1.412	0.84
1139_Q	1142_E	1.410	0.83
733_S	736_R	1.406	0.83
323_L	344_L	1.401	0.83
1506_Q	1537_K	1.401	0.83
737_F	744_Q	1.400	0.83
144_K	148_N	1.396	0.83
1064_E	1088_R	1.390	0.83
1189_E	1635_Y	1.388	0.82
1184_P	1634_M	1.387	0.82
1138_L	1486_L	1.384	0.82
1311_Y	1315_V	1.375	0.82
883_T	886_G	1.374	0.82
1179_E	1183_Y	1.373	0.82
1254_T	1282_R	1.371	0.82
1507_I	1629_P	1.367	0.82
797_W	815_D	1.366	0.81
652_Y	704_L	1.361	0.81
1195_L	1260_F	1.361	0.81
1327_L	1350_L	1.356	0.81
898_A	998_V	1.356	0.81
801_I	1534_L	1.355	0.81
484_P	902_G	1.351	0.81
1027_M	1057_L	1.350	0.81
901_S	995_E	1.346	0.80
1032_A	1124_R	1.345	0.80
458_T	1592_E	1.344	0.80
1415_Q	1418_F	1.339	0.80
1313_A	1316_L	1.339	0.80
189_A	242_L	1.337	0.80
679_N	689_Q	1.335	0.80
1531_L	1613_V	1.333	0.80
424_L	465_A	1.327	0.80
189_A	252_L	1.325	0.79
1057_L	1085_I	1.323	0.79
488_A	511_Y	1.323	0.79
1031_M	1037_S	1.319	0.79
768_R	855_E	1.317	0.79
997_R	1014_K	1.315	0.79
735_V	739_A	1.312	0.79
594_E	1624_Y	1.311	0.79
322_S	333_Q	1.311	0.79
759_T	778_A	1.307	0.78
777_I	803_V	1.305	0.78
1533_W	1611_T	1.305	0.78
1183_Y	1632_E	1.301	0.78
126_L	129_L	1.299	0.78
664_G	728_P	1.296	0.78
484_P	967_I	1.289	0.77
1447_A	1484_L	1.288	0.77
391_F	909_Y	1.286	0.77
673_R	695_L	1.283	0.77
732_V	739_A	1.281	0.77
1393_L	1401_L	1.280	0.77
863_L	896_V	1.280	0.77
773_I	812_I	1.279	0.77
775_L	825_L	1.277	0.77
1027_M	1098_I	1.275	0.77
490_N	509_V	1.273	0.77
965_V	1595_D	1.270	0.76
1100_A	1138_L	1.265	0.76
1425_T	1635_Y	1.263	0.76
1052_K	1072_A	1.258	0.76
1183_Y	1635_Y	1.258	0.76
483_M	598_R	1.256	0.76
1036_T	1623_T	1.255	0.76
539_L	653_S	1.251	0.75
866_P	869_M	1.251	0.75
485_E	902_G	1.250	0.75
883_T	889_P	1.247	0.75
505_K	570_E	1.246	0.75
1512_L	1533_W	1.246	0.75
1192_A	1260_F	1.245	0.75
1187_C	1193_S	1.244	0.75
652_Y	727_A	1.244	0.75
463_I	998_V	1.243	0.75
371_L	376_F	1.243	0.75
139_I	142_E	1.243	0.75
903_V	967_I	1.241	0.75
427_I	433_V	1.238	0.75
406_N	445_L	1.237	0.74
732_V	736_R	1.234	0.74
1249_E	1254_T	1.231	0.74
733_S	738_W	1.231	0.74
657_G	1254_T	1.230	0.74
529_L	1017_V	1.229	0.74
1179_E	1187_C	1.228	0.74
391_F	791_S	1.228	0.74
1383_G	1387_R	1.221	0.73
1193_S	1425_T	1.221	0.73
1478_N	1482_Q	1.221	0.73
729_N	732_V	1.218	0.73
91_L	124_L	1.216	0.73
1250_E	1382_Y	1.214	0.73
1055_V	1102_I	1.214	0.73
1239_G	1282_R	1.211	0.73
787_A	827_T	1.210	0.73
486_R	1024_E	1.209	0.73
402_T	451_P	1.209	0.73
898_A	1000_A	1.208	0.73
1435_A	1547_V	1.207	0.73
386_K	417_L	1.206	0.73
1223_V	1269_Y	1.206	0.73
191_N	247_N	1.203	0.72
1194_G	1198_S	1.202	0.72
425_D	466_N	1.198	0.72
564_D	702_L	1.198	0.72
129_L	161_T	1.197	0.72
965_V	992_F	1.197	0.72
1188_L	1241_A	1.197	0.72
617_I	725_V	1.191	0.72
507_S	568_R	1.190	0.72
989_I	996_L	1.189	0.71
503_E	574_E	1.185	0.71
1055_V	1454_E	1.185	0.71
1187_C	1191_T	1.184	0.71
683_D	686_W	1.183	0.71
1355_D	1358_R	1.182	0.71
489_L	602_R	1.182	0.71
134_D	160_T	1.181	0.71
1359_G	1363_I	1.181	0.71
609_W	614_L	1.181	0.71
814_V	1554_G	1.179	0.71
1131_T	1491_S	1.175	0.71
739_A	742_S	1.175	0.71
1186_G	1229_R	1.174	0.70
877_V	996_L	1.172	0.70
1600_A	1612_L	1.172	0.70
790_E	826_S	1.170	0.70
192_V	195_V	1.170	0.70
653_S	659_K	1.169	0.70
762_L	850_L	1.169	0.70
441_P	445_L	1.168	0.70
1060_S	1097_E	1.166	0.70
390_M	465_A	1.165	0.70
445_L	1003_W	1.164	0.70
863_L	998_V	1.159	0.69
1184_P	1191_T	1.158	0.69
1253_L	1257_V	1.157	0.69
1047_T	1313_A	1.155	0.69
132_K	163_D	1.154	0.69
404_I	968_V	1.154	0.69
685_G	688_S	1.154	0.69
185_L	542_F	1.151	0.69
1534_L	1616_A	1.151	0.69
1389_N	1393_L	1.150	0.69
425_D	464_R	1.148	0.69
347_D	355_A	1.146	0.69
945_L	948_G	1.146	0.69
290_S	362_T	1.146	0.69
901_S	1257_V	1.145	0.69
893_N	976_T	1.143	0.68
585_Q	605_E	1.140	0.68
341_H	798_W	1.139	0.68
613_A	652_Y	1.137	0.68
1041_L	1100_A	1.136	0.68
1043_I	1081_T	1.136	0.68
488_A	995_E	1.136	0.68
1241_A	1244_D	1.134	0.68
1140_P	1478_N	1.133	0.68
1310_S	1316_L	1.132	0.68
1187_C	1243_W	1.130	0.67
563_L	1191_T	1.130	0.67
92_D	144_K	1.128	0.67
733_S	739_A	1.126	0.67
314_A	784_K	1.125	0.67
1179_E	1190_Q	1.125	0.67
879_I	1452_S	1.125	0.67
734_S	739_A	1.118	0.67
138_T	156_E	1.118	0.67
1038_R	1624_Y	1.116	0.67
760_L	810_L	1.114	0.66
1390_A	1413_L	1.113	0.66
89_I	147_N	1.111	0.66
1631_V	1641_A	1.110	0.66
200_F	234_L	1.109	0.66
1039_L	1057_L	1.109	0.66
1263_R	1266_E	1.109	0.66
129_L	135_L	1.109	0.66
892_V	1004_T	1.106	0.66
1220_R	1224_D	1.106	0.66
1262_V	1319_Q	1.105	0.66
1527_G	1536_V	1.104	0.66
859_L	1002_A	1.104	0.66
785_G	801_I	1.102	0.66
1180_L	1185_Y	1.100	0.65
641_D	644_S	1.100	0.65
786_Y	790_E	1.099	0.65
781_T	831_R	1.098	0.65
1075_L	1081_T	1.098	0.65
776_H	809_D	1.096	0.65
537_S	540_P	1.095	0.65
705_K	708_E	1.092	0.65
317_Q	338_A	1.092	0.65
139_I	155_Y	1.092	0.65
1287_L	1290_P	1.090	0.65
1507_I	1631_V	1.089	0.65
1417_A	1608_Q	1.088	0.64
1218_K	1221_A	1.086	0.64
391_F	1001_Q	1.086	0.64
861_L	1011_N	1.085	0.64
901_S	905_N	1.084	0.64
447_H	974_P	1.084	0.64
452_L	477_F	1.083	0.64
741_Y	746_N	1.083	0.64
105_D	126_L	1.083	0.64
480_E	1561_N	1.082	0.64
620_Q	649_D	1.081	0.64
702_L	712_V	1.081	0.64
1504_V	1641_A	1.079	0.64
824_Y	847_V	1.078	0.64
308_Q	932_Y	1.077	0.64
1443_G	1624_Y	1.075	0.64
894_V	1002_A	1.075	0.64
1383_G	1388_D	1.074	0.63
1037_S	1620_T	1.073	0.63
408_L	1631_V	1.073	0.63
678_W	681_S	1.069	0.63
406_N	971_Q	1.067	0.63
461_W	879_I	1.067	0.63
1509_R	1614_Y	1.066	0.63
117_L	124_L	1.065	0.63
1137_A	1483_P	1.065	0.63
321_V	324_L	1.063	0.63
389_F	914_P	1.063	0.63
476_D	811_T	1.062	0.63
445_L	893_N	1.062	0.63
308_Q	830_V	1.062	0.63
1541_S	1607_Y	1.061	0.63
678_W	685_G	1.059	0.62
101_I	117_L	1.059	0.62
458_T	481_D	1.058	0.62
523_L	592_L	1.057	0.62
1018_A	1624_Y	1.056	0.62
321_V	355_A	1.052	0.62
482_F	903_V	1.050	0.62
1179_E	1189_E	1.049	0.62
1041_L	1085_I	1.048	0.62
997_R	1012_E	1.047	0.61
1345_Q	1391_L	1.043	0.61
906_I	1560_Q	1.042	0.61
88_S	1086_P	1.039	0.61
481_D	1259_D	1.038	0.61
482_F	967_I	1.036	0.61
940_G	943_A	1.036	0.61
904_L	999_M	1.035	0.61
314_A	335_T	1.033	0.60
790_E	1184_P	1.033	0.60
859_L	1009_G	1.032	0.60
1129_A	1491_S	1.031	0.60
909_Y	999_M	1.030	0.60
671_R	721_Y	1.030	0.60
886_G	889_P	1.030	0.60
83_L	129_L	1.029	0.60
1235_R	1245_K	1.028	0.60
145_A	149_A	1.028	0.60
126_L	161_T	1.026	0.60
1377_I	1380_G	1.024	0.60
517_P	997_R	1.023	0.60
295_S	828_L	1.019	0.59
600_V	1197_P	1.019	0.59
1621_P	1624_Y	1.019	0.59
668_R	696_I	1.018	0.59
101_I	1087_V	1.018	0.59
739_A	744_Q	1.017	0.59
735_V	740_G	1.016	0.59
777_I	785_G	1.016	0.59
679_N	685_G	1.015	0.59
667_V	725_V	1.014	0.59
136_I	156_E	1.013	0.59
685_G	690_F	1.009	0.59
89_I	149_A	1.009	0.59
775_L	850_L	1.008	0.58
194_N	241_D	1.007	0.58
967_I	992_F	1.006	0.58
1620_T	1624_Y	1.006	0.58
970_Q	987_L	1.005	0.58
732_V	735_V	1.002	0.58
1161_G	1488_M	1.001	0.58
753_V	759_T	1.000	0.58
1394_S	1400_K	0.999	0.58
737_F	743_W	0.998	0.58
481_D	1594_R	0.998	0.58
195_V	242_L	0.998	0.58
137_V	358_D	0.993	0.57
814_V	1482_Q	0.991	0.57
861_L	894_V	0.991	0.57
483_M	1527_G	0.991	0.57
852_L	1554_G	0.990	0.57
1234_Q	1279_G	0.990	0.57
619_P	648_F	0.989	0.57
1188_L	1240_F	0.987	0.57
395_D	907_T	0.987	0.57
681_S	685_G	0.984	0.57
1043_I	1056_A	0.984	0.57
355_A	358_D	0.982	0.56
1025_L	1117_K	0.979	0.56
1268_G	1271_V	0.979	0.56
1286_Y	1289_D	0.978	0.56
1362_A	1366_A	0.977	0.56
1409_L	1505_L	0.976	0.56
1229_R	1233_M	0.976	0.56
1255_A	1283_L	0.976	0.56
398_R	536_V	0.975	0.56
909_Y	912_P	0.973	0.56
734_S	741_Y	0.973	0.56
1529_L	1615_L	0.972	0.56
1600_A	1614_Y	0.969	0.55
877_V	987_L	0.968	0.55
1476_V	1616_A	0.968	0.55
1344_L	1392_M	0.967	0.55
1054_N	1103_S	0.967	0.55
668_R	699_E	0.967	0.55
883_T	890_K	0.964	0.55
676_Y	686_W	0.964	0.55
594_E	974_P	0.964	0.55
362_T	789_V	0.963	0.55
1528_D	1618_A	0.963	0.55
297_H	786_Y	0.963	0.55
1257_V	1261_L	0.962	0.55
456_A	461_W	0.962	0.55
1240_F	1275_A	0.961	0.55
1221_A	1225_I	0.961	0.55
117_L	120_N	0.961	0.55
523_L	590_G	0.959	0.55
492_T	509_V	0.958	0.55
405_L	1041_L	0.956	0.54
240_F	254_L	0.955	0.54
737_F	745_D	0.954	0.54
911_T	999_M	0.954	0.54
409_L	422_I	0.952	0.54
1096_G	1123_V	0.951	0.54
679_N	683_D	0.951	0.54
903_V	992_F	0.951	0.54
1448_Q	1479_S	0.951	0.54
814_V	823_L	0.951	0.54
319_I	504_V	0.951	0.54
712_V	879_I	0.950	0.54
295_S	928_I	0.950	0.54
764_K	790_E	0.950	0.54
1064_E	1068_D	0.949	0.54
1594_R	1597_R	0.949	0.54
679_N	682_E	0.948	0.54
1426_Q	1634_M	0.948	0.54
426_V	1202_N	0.947	0.54
1544_D	1633_S	0.945	0.54
773_I	825_L	0.944	0.53
1279_G	1282_R	0.944	0.53
438_V	1265_G	0.944	0.53
975_V	985_V	0.944	0.53
118_S	143_V	0.943	0.53
1384_S	1426_Q	0.941	0.53
1410_L	1414_S	0.940	0.53
1044_T	1080_R	0.940	0.53
196_D	273_N	0.939	0.53
676_Y	679_N	0.939	0.53
1037_S	1553_A	0.938	0.53
822_D	853_G	0.938	0.53
512_Y	516_A	0.934	0.53
304_D	795_P	0.932	0.53
1056_A	1070_P	0.931	0.52
102_H	118_S	0.930	0.52
676_Y	688_S	0.930	0.52
522_T	560_Q	0.929	0.52
1511_I	1532_V	0.928	0.52
562_T	913_D	0.927	0.52
818_W	823_L	0.927	0.52
1344_L	1409_L	0.927	0.52
94_D	103_V	0.926	0.52
452_L	456_A	0.925	0.52
1041_L	1552_P	0.924	0.52
1052_K	1056_A	0.922	0.52
984_S	1650_I	0.922	0.52
1509_R	1532_V	0.921	0.52
518_A	597_G	0.919	0.52
1098_I	1102_I	0.919	0.52
867_A	1013_S	0.918	0.51
943_A	948_G	0.916	0.51
666_Q	726_K	0.916	0.51
1275_A	1279_G	0.915	0.51
263_Q	563_L	0.913	0.51
1452_S	1455_Q	0.912	0.51
1283_L	1289_D	0.911	0.51
1037_S	1624_Y	0.911	0.51
879_I	975_V	0.910	0.51
1393_L	1410_L	0.910	0.51
405_L	424_L	0.910	0.51
330_T	1123_V	0.909	0.51
1056_A	1101_T	0.908	0.51
729_N	733_S	0.908	0.51
1536_V	1631_V	0.907	0.51
977_L	980_Q	0.907	0.51
1184_P	1635_Y	0.906	0.50
863_L	1142_E	0.906	0.50
1025_L	1557_L	0.904	0.50
1243_W	1596_D	0.904	0.50
1179_E	1634_M	0.902	0.50
434_L	1650_I	0.901	0.50
1043_I	1066_V	0.900	0.50
1461_A	1464_S	0.900	0.50
1032_A	1550_L	0.899	0.50
1258_M	1283_L	0.899	0.50
352_L	355_A	0.898	0.50
1063_L	1185_Y	0.897	0.50
861_L	881_A	0.897	0.50
351_A	354_L	0.897	0.50
1183_Y	1193_S	0.897	0.50
507_S	779_A	0.896	0.50
337_D	774_K	0.895	0.50
314_A	1083_L	0.895	0.50
340_G	515_G	0.895	0.50
451_P	454_S	0.895	0.50
115_W	161_T	0.895	0.50
991_D	1117_K	0.893	0.49
650_I	702_L	0.892	0.49
762_L	775_L	0.891	0.49
870_R	1112_V	0.891	0.49
140_G	144_K	0.891	0.49
502_D	1431_L	0.890	0.49
106_K	143_V	0.890	0.49
393_P	397_Y	0.889	0.49
696_I	699_E	0.889	0.49
307_T	336_S	0.888	0.49
1049_K	1104_G	0.888	0.49
428_K	985_V	0.888	0.49
100_V	134_D	0.888	0.49
337_D	343_Q	0.887	0.49
784_K	800_E	0.887	0.49
290_S	414_G	0.886	0.49
1395_L	1399_N	0.885	0.49
84_V	125_R	0.883	0.49
1187_C	1256_Y	0.883	0.49
1383_G	1424_S	0.883	0.49
142_E	159_I	0.882	0.49
772_T	789_V	0.882	0.49
650_I	1477_S	0.878	0.48
683_D	687_Q	0.877	0.48
1384_S	1429_N	0.876	0.48
671_R	717_E	0.876	0.48
1201_T	1432_F	0.875	0.48
881_A	892_V	0.875	0.48
1500_P	1643_G	0.873	0.48
100_V	140_G	0.873	0.48
978_N	981_G	0.871	0.48
725_V	1161_G	0.870	0.48
1031_M	1121_I	0.869	0.48
998_V	1015_V	0.868	0.47
767_Y	846_G	0.867	0.47
1180_L	1183_Y	0.867	0.47
137_V	157_K	0.867	0.47
1627_P	1632_E	0.867	0.47
85_L	1491_S	0.866	0.47
813_P	818_W	0.866	0.47
1193_S	1634_M	0.866	0.47
290_S	664_G	0.865	0.47
731_A	740_G	0.864	0.47
881_A	977_L	0.864	0.47
1306_F	1313_A	0.864	0.47
1121_I	1422_W	0.863	0.47
672_E	722_R	0.863	0.47
429_P	461_W	0.862	0.47
404_I	969_V	0.861	0.47
484_P	992_F	0.860	0.47
879_I	1081_T	0.859	0.47
508_V	903_V	0.859	0.47
290_S	914_P	0.859	0.47
349_N	353_L	0.859	0.47
85_L	103_V	0.858	0.47
866_P	875_L	0.858	0.47
1029_R	1594_R	0.858	0.47
293_G	310_L	0.856	0.47
1451_F	1474_L	0.856	0.47
1146_I	1543_P	0.855	0.46
940_G	948_G	0.855	0.46
733_S	741_Y	0.855	0.46
1190_Q	1243_W	0.855	0.46
1031_M	1057_L	0.854	0.46
328_G	376_F	0.853	0.46
697_E	863_L	0.853	0.46
896_V	985_V	0.853	0.46
118_S	126_L	0.852	0.46
758_V	829_V	0.851	0.46
686_W	689_Q	0.851	0.46
130_E	135_L	0.851	0.46
1078_G	1476_V	0.851	0.46
1045_N	1545_A	0.850	0.46
487_M	994_G	0.849	0.46
948_G	951_G	0.848	0.46
1536_V	1639_W	0.848	0.46
1056_A	1103_S	0.847	0.46
322_S	330_T	0.847	0.46
106_K	138_T	0.847	0.46
598_R	1620_T	0.846	0.46
335_T	701_T	0.846	0.46
410_R	512_Y	0.846	0.46
423_K	436_S	0.846	0.46
1189_E	1256_Y	0.845	0.46
1507_I	1536_V	0.844	0.46
1549_D	1616_A	0.844	0.46
678_W	688_S	0.844	0.46
788_M	826_S	0.844	0.46
796_L	1558_E	0.843	0.45
1343_L	1365_L	0.843	0.45
1396_L	1509_R	0.843	0.45
1565_G	1588_I	0.843	0.45
305_I	906_I	0.842	0.45
564_D	725_V	0.841	0.45
1383_G	1390_A	0.841	0.45
373_L	517_P	0.841	0.45
596_G	1126_A	0.841	0.45
194_N	239_R	0.840	0.45
890_K	1007_D	0.839	0.45
1040_T	1084_F	0.838	0.45
339_Q	1218_K	0.837	0.45
797_W	801_I	0.837	0.45
1188_L	1197_P	0.836	0.45
1234_Q	1239_G	0.835	0.45
1038_R	1086_P	0.835	0.45
618_R	771_D	0.834	0.45
1548_V	1632_E	0.834	0.45
1407_Y	1410_L	0.834	0.45
390_M	424_L	0.834	0.45
686_W	690_F	0.832	0.45
313_G	1511_I	0.832	0.45
1196_F	1263_R	0.831	0.45
1390_A	1554_G	0.831	0.45
1197_P	1252_W	0.829	0.44
324_L	354_L	0.828	0.44
235_V	358_D	0.827	0.44
1311_Y	1318_R	0.827	0.44
1256_Y	1425_T	0.827	0.44
297_H	926_A	0.826	0.44
1063_L	1089_A	0.825	0.44
738_W	741_Y	0.823	0.44
859_L	1347_G	0.823	0.44
144_K	150_T	0.823	0.44
396_L	967_I	0.823	0.44
598_R	1619_V	0.823	0.44
1548_V	1599_V	0.822	0.44
788_M	798_W	0.822	0.44
705_K	712_V	0.822	0.44
1405_E	1408_T	0.822	0.44
669_L	714_F	0.822	0.44
461_W	892_V	0.821	0.44
702_L	707_D	0.821	0.44
1234_Q	1240_F	0.820	0.44
1095_D	1120_K	0.820	0.44
795_P	926_A	0.820	0.44
392_G	397_Y	0.819	0.44
694_D	722_R	0.819	0.44
202_V	1536_V	0.819	0.44
816_K	1123_V	0.819	0.44
89_I	145_A	0.818	0.44
654_D	1603_A	0.817	0.43
512_Y	563_L	0.817	0.43
574_E	608_I	0.817	0.43
1021_V	1266_E	0.817	0.43
1528_D	1650_I	0.816	0.43
290_S	1443_G	0.816	0.43
492_T	568_R	0.816	0.43
821_H	965_V	0.816	0.43
103_V	135_L	0.816	0.43
1404_D	1408_T	0.816	0.43
746_N	1123_V	0.814	0.43
1062_L	1065_L	0.814	0.43
1074_E	1645_A	0.814	0.43
542_F	789_V	0.814	0.43
478_H	907_T	0.813	0.43
1252_W	1426_Q	0.813	0.43
598_R	903_V	0.813	0.43
801_I	810_L	0.812	0.43
588_F	606_Q	0.812	0.43
1185_Y	1193_S	0.812	0.43
697_E	702_L	0.812	0.43
858_R	1650_I	0.812	0.43
319_I	357_K	0.811	0.43
1387_R	1634_M	0.810	0.43
869_M	1015_V	0.810	0.43
1023_A	1102_I	0.809	0.43
944_A	948_G	0.809	0.43
533_R	1156_P	0.808	0.43
936_I	949_G	0.808	0.43
458_T	1260_F	0.808	0.43
458_T	1594_R	0.807	0.43
852_L	1123_V	0.807	0.43
136_I	769_P	0.806	0.43
139_I	863_L	0.806	0.43
1190_Q	1193_S	0.806	0.43
994_G	1492_G	0.806	0.43
1126_A	1612_L	0.806	0.43
104_V	137_V	0.806	0.43
1593_F	1598_F	0.805	0.43
1031_M	1041_L	0.805	0.43
943_A	947_F	0.805	0.43
1250_E	1544_D	0.805	0.43
683_D	689_Q	0.804	0.42
139_I	146_L	0.803	0.42
331_L	587_I	0.803	0.42
882_S	886_G	0.803	0.42
393_P	563_L	0.803	0.42
921_Q	1631_V	0.802	0.42
1347_G	1395_L	0.802	0.42
681_S	689_Q	0.802	0.42
1273_T	1276_I	0.801	0.42
520_G	1080_R	0.801	0.42
85_L	991_D	0.800	0.42
396_L	906_I	0.800	0.42
88_S	1488_M	0.799	0.42
297_H	788_M	0.799	0.42
1261_L	1271_V	0.798	0.42
670_I	722_R	0.798	0.42
665_L	727_A	0.798	0.42
714_F	1507_I	0.797	0.42
1387_R	1390_A	0.797	0.42
491_L	604_A	0.797	0.42
174_G	994_G	0.797	0.42
514_Y	600_V	0.796	0.42
254_L	504_V	0.796	0.42
1259_D	1263_R	0.796	0.42
1413_L	1431_L	0.795	0.42
1212_K	1536_V	0.795	0.42
316_Q	357_K	0.794	0.42
85_L	139_I	0.793	0.42
833_G	836_S	0.793	0.42
409_L	998_V	0.791	0.41
1104_G	1110_E	0.791	0.41
353_L	356_R	0.790	0.41
1512_L	1531_L	0.790	0.41
512_Y	1080_R	0.790	0.41
1341_L	1345_Q	0.790	0.41
766_S	853_G	0.790	0.41
1527_G	1538_A	0.790	0.41
1088_R	1541_S	0.788	0.41
872_N	1019_A	0.788	0.41
1458_G	1461_A	0.787	0.41
401_E	967_I	0.787	0.41
934_Q	1002_A	0.787	0.41
1124_R	1597_R	0.787	0.41
1351_K	1356_A	0.786	0.41
1021_V	1046_L	0.785	0.41
1058_T	1101_T	0.785	0.41
732_V	741_Y	0.784	0.41
287_F	290_S	0.784	0.41
1100_A	1525_R	0.784	0.41
355_A	360_Q	0.782	0.41
270_A	1315_V	0.782	0.41
824_Y	950_D	0.782	0.41
590_G	1643_G	0.782	0.41
1188_L	1261_L	0.782	0.41
585_Q	894_V	0.781	0.41
529_L	584_L	0.780	0.41
403_V	465_A	0.780	0.41
1038_R	1084_F	0.779	0.40
796_L	1157_V	0.779	0.40
969_V	990_G	0.778	0.40
1523_S	1649_L	0.778	0.40
771_D	828_L	0.778	0.40
810_L	813_P	0.778	0.40
650_I	712_V	0.777	0.40
768_R	853_G	0.777	0.40
1406_Q	1410_L	0.777	0.40
962_V	971_Q	0.776	0.40
1524_L	1648_L	0.775	0.40
426_V	450_W	0.775	0.40
1528_D	1532_V	0.775	0.40
1413_L	1417_A	0.775	0.40
306_F	786_Y	0.774	0.40
83_L	155_Y	0.774	0.40
1503_N	1507_I	0.773	0.40
788_M	795_P	0.773	0.40
979_E	1534_L	0.772	0.40
1023_A	1043_I	0.772	0.40
314_A	879_I	0.772	0.40
702_L	710_G	0.771	0.40
123_E	126_L	0.769	0.40
1546_L	1599_V	0.769	0.40
312_N	816_K	0.768	0.40
1084_F	1268_G	0.768	0.40
302_R	343_Q	0.767	0.40
710_G	714_F	0.767	0.40
1522_D	1638_Q	0.767	0.40
321_V	1036_T	0.767	0.40
649_D	711_K	0.766	0.40
1141_G	1480_G	0.766	0.40
468_G	1650_I	0.766	0.40
877_V	1062_L	0.765	0.39
1230_L	1257_V	0.765	0.39
1317_A	1362_A	0.765	0.39
769_P	852_L	0.764	0.39
532_L	585_Q	0.764	0.39
519_N	1194_G	0.762	0.39
1344_L	1395_L	0.762	0.39
492_T	507_S	0.761	0.39
518_A	521_N	0.761	0.39
880_K	1479_S	0.761	0.39
1165_L	1484_L	0.761	0.39
514_Y	1044_T	0.761	0.39
316_Q	355_A	0.761	0.39
893_N	993_N	0.760	0.39
362_T	365_D	0.759	0.39
1559_N	1562_L	0.758	0.39
498_L	504_V	0.758	0.39
1255_A	1612_L	0.758	0.39
292_I	319_I	0.757	0.39
1310_S	1314_L	0.757	0.39
850_L	1188_L	0.757	0.39
1186_G	1226_G	0.757	0.39
926_A	932_Y	0.756	0.39
115_W	129_L	0.756	0.39
1180_L	1190_Q	0.756	0.39
864_E	982_E	0.755	0.39
481_D	1549_D	0.755	0.39
861_L	1009_G	0.755	0.39
1544_D	1603_A	0.752	0.38
480_E	1190_Q	0.751	0.38
734_S	744_Q	0.751	0.38
1073_V	1076_A	0.750	0.38
1179_E	1425_T	0.750	0.38
1098_I	1530_V	0.750	0.38
387_Q	922_K	0.750	0.38
396_L	1131_T	0.749	0.38
618_R	649_D	0.749	0.38
1183_Y	1194_G	0.749	0.38
483_M	1029_R	0.749	0.38
341_H	795_P	0.749	0.38
1186_G	1597_R	0.748	0.38
566_K	1224_D	0.748	0.38
760_L	1346_L	0.747	0.38
729_N	1485_W	0.747	0.38
1189_E	1390_A	0.747	0.38
481_D	1595_D	0.746	0.38
125_R	128_H	0.746	0.38
1555_L	1650_I	0.746	0.38
1183_Y	1191_T	0.746	0.38
335_T	550_E	0.745	0.38
868_K	1047_T	0.745	0.38
461_W	1478_N	0.745	0.38
1239_G	1562_L	0.745	0.38
1242_L	1253_L	0.744	0.38
1184_P	1193_S	0.744	0.38
1364_A	1368_K	0.744	0.38
117_L	126_L	0.744	0.38
1190_Q	1197_P	0.744	0.38
650_I	704_L	0.743	0.38
1203_A	1267_Q	0.742	0.38
1145_A	1473_T	0.742	0.38
656_Q	1099_Q	0.742	0.38
502_D	656_Q	0.742	0.38
1390_A	1426_Q	0.741	0.38
103_V	1452_S	0.741	0.38
566_K	1063_L	0.741	0.38
678_W	718_W	0.741	0.38
1083_L	1086_P	0.740	0.38
1556_E	1619_V	0.740	0.38
1282_R	1287_L	0.740	0.38
1189_E	1617_R	0.739	0.37
989_I	1100_A	0.739	0.37
771_D	827_T	0.739	0.37
843_R	930_D	0.739	0.37
428_K	434_L	0.738	0.37
891_Q	1236_D	0.738	0.37
1081_T	1110_E	0.738	0.37
271_V	284_A	0.737	0.37
870_R	986_T	0.736	0.37
790_E	928_I	0.736	0.37
525_G	590_G	0.736	0.37
245_A	248_T	0.735	0.37
685_G	689_Q	0.735	0.37
819_N	854_D	0.734	0.37
503_E	572_S	0.734	0.37
771_D	1265_G	0.733	0.37
318_G	336_S	0.733	0.37
1185_Y	1635_Y	0.732	0.37
114_A	127_R	0.732	0.37
353_L	1012_E	0.732	0.37
826_S	847_V	0.732	0.37
1554_G	1617_R	0.732	0.37
658_V	1368_K	0.732	0.37
1194_G	1222_S	0.731	0.37
391_F	1595_D	0.731	0.37
1188_L	1191_T	0.731	0.37
794_G	1043_I	0.731	0.37
306_F	341_H	0.730	0.37
1457_T	1460_K	0.730	0.37
321_V	1320_Q	0.730	0.37
765_A	1503_N	0.730	0.37
796_L	1476_V	0.730	0.37
735_V	738_W	0.729	0.37
1046_L	1548_V	0.729	0.37
577_W	580_T	0.729	0.37
482_F	593_L	0.729	0.37
100_V	142_E	0.728	0.37
99_R	103_V	0.728	0.37
139_I	1451_F	0.727	0.37
694_D	699_E	0.727	0.37
993_N	1315_V	0.727	0.37
811_T	1036_T	0.726	0.37
256_L	1395_L	0.726	0.37
177_L	181_V	0.725	0.36
1305_K	1310_S	0.725	0.36
260_K	1131_T	0.725	0.36
1094_G	1123_V	0.725	0.36
142_E	152_S	0.725	0.36
202_V	936_I	0.724	0.36
1525_R	1651_V	0.724	0.36
1154_F	1492_G	0.724	0.36
514_Y	1022_I	0.724	0.36
656_Q	702_L	0.723	0.36
736_R	741_Y	0.722	0.36
1384_S	1559_N	0.722	0.36
1014_K	1102_I	0.721	0.36
429_P	1241_A	0.721	0.36
205_E	329_Q	0.721	0.36
1042_D	1080_R	0.721	0.36
608_I	1103_S	0.720	0.36
461_W	767_Y	0.719	0.36
1544_D	1589_K	0.719	0.36
1527_G	1622_G	0.719	0.36
669_L	697_E	0.718	0.36
390_M	1434_A	0.718	0.36
850_L	1055_V	0.718	0.36
482_F	898_A	0.718	0.36
380_G	849_H	0.717	0.36
1362_A	1374_D	0.717	0.36
1462_Q	1465_N	0.716	0.36
360_Q	1051_Q	0.716	0.36
86_T	92_D	0.716	0.36
1358_R	1366_A	0.715	0.36
138_T	154_D	0.715	0.36
417_L	1050_P	0.715	0.36
470_N	1507_I	0.715	0.36
463_I	477_F	0.714	0.36
508_V	1098_I	0.713	0.36
494_E	497_P	0.713	0.36
1035_D	1553_A	0.713	0.36
880_K	1078_G	0.712	0.35
1065_L	1087_V	0.712	0.35
1180_L	1187_C	0.712	0.35
1507_I	1624_Y	0.712	0.35
527_L	1021_V	0.712	0.35
1310_S	1330_I	0.712	0.35
484_P	1596_D	0.711	0.35
372_D	375_E	0.711	0.35
1039_L	1188_L	0.711	0.35
484_P	904_L	0.711	0.35
908_D	919_F	0.710	0.35
482_F	1195_L	0.710	0.35
803_V	829_V	0.710	0.35
954_L	1237_N	0.709	0.35
1187_C	1426_Q	0.708	0.35
771_D	1270_S	0.708	0.35
914_P	1094_G	0.707	0.35
434_L	1071_A	0.707	0.35
1243_W	1634_M	0.707	0.35
1333_H	1337_A	0.706	0.35
1188_L	1235_R	0.706	0.35
1406_Q	1429_N	0.705	0.35
1189_E	1243_W	0.705	0.35
962_V	1114_D	0.705	0.35
617_I	796_L	0.705	0.35
742_S	745_D	0.704	0.35
105_D	129_L	0.703	0.35
408_L	914_P	0.703	0.35
767_Y	814_V	0.703	0.35
345_E	862_A	0.702	0.35
541_G	813_P	0.702	0.35
1103_S	1450_S	0.701	0.35
1386_L	1413_L	0.701	0.35
783_G	1550_L	0.701	0.35
604_A	607_A	0.700	0.35
678_W	682_E	0.700	0.35
1256_Y	1634_M	0.700	0.35
268_Y	430_D	0.700	0.35
598_R	992_F	0.700	0.35
401_E	477_F	0.700	0.35
151_F	998_V	0.700	0.35
1258_M	1261_L	0.700	0.35
899_V	1627_P	0.699	0.35
810_L	980_Q	0.699	0.35
1509_R	1534_L	0.698	0.34
704_L	708_E	0.698	0.34
811_T	986_T	0.698	0.34
1384_S	1388_D	0.698	0.34
158_T	453_D	0.697	0.34
1185_Y	1243_W	0.697	0.34
618_R	1192_A	0.697	0.34
240_F	520_G	0.697	0.34
1239_G	1384_S	0.696	0.34
1183_Y	1617_R	0.696	0.34
1625_Q	1647_D	0.696	0.34
465_A	771_D	0.695	0.34
1190_Q	1194_G	0.695	0.34
334_A	936_I	0.694	0.34
1340_G	1388_D	0.693	0.34
979_E	1043_I	0.693	0.34
438_V	446_Y	0.693	0.34
153_K	167_S	0.692	0.34
1454_E	1477_S	0.692	0.34
256_L	587_I	0.691	0.34
1183_Y	1256_Y	0.691	0.34
1478_N	1484_L	0.691	0.34
321_V	1507_I	0.691	0.34
912_P	1186_G	0.691	0.34
1133_N	1413_L	0.690	0.34
1412_T	1416_Q	0.690	0.34
1456_L	1460_K	0.689	0.34
1343_L	1369_T	0.689	0.34
104_V	135_L	0.689	0.34
1283_L	1287_L	0.689	0.34
1075_L	1468_S	0.688	0.34
397_Y	452_L	0.688	0.34
1021_V	1053_L	0.687	0.34
104_V	121_L	0.687	0.34
484_P	994_G	0.687	0.34
377_N	431_G	0.687	0.34
844_A	996_L	0.687	0.34
772_T	1487_R	0.686	0.34
1448_Q	1457_T	0.686	0.34
1088_R	1254_T	0.686	0.34
91_L	97_F	0.686	0.34
116_E	144_K	0.686	0.34
501_K	896_V	0.686	0.34
769_P	796_L	0.686	0.34
318_G	344_L	0.686	0.34
1534_L	1643_G	0.685	0.34
443_N	893_N	0.685	0.34
1411_N	1650_I	0.684	0.33
197_V	1079_V	0.684	0.33
290_S	837_R	0.684	0.33
1422_W	1650_I	0.684	0.33
335_T	1058_T	0.683	0.33
390_M	475_W	0.683	0.33
1542_V	1633_S	0.682	0.33
191_N	846_G	0.682	0.33
1387_R	1391_L	0.682	0.33
202_V	1618_A	0.682	0.33
740_G	743_W	0.682	0.33
787_A	1100_A	0.682	0.33
610_P	1627_P	0.682	0.33
1396_L	1511_I	0.682	0.33
284_A	1633_S	0.682	0.33
264_Q	1454_E	0.681	0.33
896_V	1139_Q	0.681	0.33
1235_R	1241_A	0.680	0.33
1183_Y	1186_G	0.680	0.33
663_S	727_A	0.680	0.33
195_V	1140_P	0.680	0.33
538_A	658_V	0.679	0.33
1549_D	1637_P	0.679	0.33
405_L	426_V	0.678	0.33
777_I	816_K	0.678	0.33
1097_E	1120_K	0.678	0.33
100_V	143_V	0.677	0.33
731_A	737_F	0.677	0.33
479_V	1165_L	0.677	0.33
1365_L	1369_T	0.677	0.33
904_L	1627_P	0.677	0.33
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783_G	1311_Y	0.676	0.33
1218_K	1222_S	0.676	0.33
458_T	1169_P	0.675	0.33
1546_L	1634_M	0.675	0.33
1186_G	1190_Q	0.675	0.33
128_H	131_P	0.674	0.33
613_A	727_A	0.674	0.33
821_H	852_L	0.674	0.33
430_D	457_A	0.673	0.33
817_T	1450_S	0.673	0.33
1190_Q	1617_R	0.673	0.33
822_D	1031_M	0.672	0.33
1063_L	1096_G	0.672	0.33
517_P	908_D	0.672	0.33
457_A	461_W	0.672	0.33
729_N	1076_A	0.672	0.33
421_P	439_S	0.672	0.33
1079_V	1472_V	0.671	0.33
1050_P	1074_E	0.671	0.33
1394_S	1398_E	0.670	0.32
708_E	928_I	0.670	0.32
553_S	650_I	0.670	0.32
814_V	1451_F	0.669	0.32
1316_L	1319_Q	0.668	0.32
1265_G	1273_T	0.668	0.32
1555_L	1614_Y	0.667	0.32
1535_Q	1609_P	0.667	0.32
130_E	152_S	0.666	0.32
771_D	1165_L	0.666	0.32
1616_A	1648_L	0.665	0.32
89_I	143_V	0.664	0.32
1486_L	1490_A	0.664	0.32
230_Q	658_V	0.664	0.32
426_V	463_I	0.664	0.32
178_P	1644_A	0.664	0.32
568_R	1023_A	0.664	0.32
358_D	1236_D	0.663	0.32
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426_V	1547_V	0.662	0.32
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224_Q	1624_Y	0.662	0.32
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1448_Q	1477_S	0.662	0.32
506_F	736_R	0.662	0.32
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294_V	362_T	0.662	0.32
1125_P	1560_Q	0.661	0.32
763_D	771_D	0.661	0.32
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461_W	1047_T	0.660	0.32
510_G	521_N	0.660	0.32
863_L	978_N	0.659	0.32
1305_K	1316_L	0.659	0.32
881_A	1000_A	0.659	0.32
1417_A	1420_E	0.659	0.32
310_L	935_V	0.659	0.32
1062_L	1096_G	0.659	0.32
650_I	768_R	0.659	0.32
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328_G	331_L	0.658	0.32
1053_L	1102_I	0.658	0.32
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1534_L	1555_L	0.657	0.32
437_V	1087_V	0.657	0.32
399_P	1595_D	0.657	0.32
242_L	1055_V	0.657	0.32
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294_V	321_V	0.656	0.32
1388_D	1392_M	0.656	0.32
513_L	608_I	0.656	0.32
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1192_A	1195_L	0.655	0.31
1187_C	1632_E	0.655	0.31
827_T	1552_P	0.655	0.31
480_E	1187_C	0.655	0.31
1184_P	1243_W	0.654	0.31
804_R	808_L	0.654	0.31
1216_D	1219_R	0.654	0.31
426_V	1021_V	0.653	0.31
1541_S	1609_P	0.652	0.31
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124_L	139_I	0.652	0.31
529_L	586_V	0.651	0.31
640_V	646_A	0.651	0.31
762_L	825_L	0.651	0.31
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314_A	1054_N	0.651	0.31
1452_S	1472_V	0.650	0.31
986_T	1555_L	0.650	0.31
372_D	380_G	0.650	0.31
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563_L	596_G	0.649	0.31
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1395_L	1409_L	0.649	0.31
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315_A	1483_P	0.648	0.31
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380_G	421_P	0.646	0.31
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1513_G	1516_G	0.645	0.31
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1053_L	1104_G	0.644	0.31
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363_L	831_R	0.644	0.31
442_E	568_R	0.644	0.31
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1559_N	1634_M	0.643	0.31
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914_P	1001_Q	0.643	0.31
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1421_R	1638_Q	0.639	0.30
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617_I	650_I	0.636	0.30
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787_A	829_V	0.636	0.30
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1476_V	1489_D	0.635	0.30
965_V	1117_K	0.635	0.30
1019_A	1114_D	0.635	0.30
391_F	1323_P	0.635	0.30
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514_Y	598_R	0.634	0.30
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1126_A	1158_T	0.633	0.30
1449_T	1453_A	0.633	0.30
719_G	1527_G	0.632	0.30
1554_G	1650_I	0.632	0.30
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1449_T	1650_I	0.631	0.30
1198_S	1222_S	0.630	0.30
1123_V	1585_Q	0.630	0.30
1183_Y	1426_Q	0.630	0.30
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946_R	949_G	0.630	0.30
1456_L	1461_A	0.629	0.30
734_S	738_W	0.629	0.30
403_V	1451_F	0.629	0.30
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483_M	993_N	0.628	0.30
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491_L	1409_L	0.627	0.30
1311_Y	1317_A	0.627	0.30
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1145_A	1475_Q	0.627	0.30
349_N	358_D	0.627	0.30
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1143_T	1449_T	0.626	0.30
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253_L	426_V	0.626	0.30
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347_D	358_D	0.626	0.30
1043_I	1100_A	0.625	0.29
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1614_Y	1637_P	0.625	0.29
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1311_Y	1319_Q	0.624	0.29
297_H	822_D	0.624	0.29
1124_R	1550_L	0.624	0.29
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1417_A	1422_W	0.622	0.29
1034_G	1530_V	0.621	0.29
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1331_W	1361_E	0.619	0.29
1191_T	1529_L	0.618	0.29
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1047_T	1628_Q	0.616	0.29
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1507_I	1641_A	0.612	0.29
101_I	123_E	0.612	0.29
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1191_T	1194_G	0.611	0.29
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530_R	1043_I	0.608	0.28
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1588_I	1612_L	0.602	0.28
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1511_I	1614_Y	0.584	0.27
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1326_A	1329_E	0.578	0.26
289_L	490_N	0.577	0.26
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858_R	913_D	0.577	0.26
763_D	775_L	0.576	0.26
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1063_L	1072_A	0.508	0.22
783_G	1617_R	0.507	0.22
1180_L	1243_W	0.507	0.22
1460_K	1465_N	0.507	0.22
1193_S	1635_Y	0.507	0.22
339_Q	1055_V	0.507	0.22
236_Y	287_F	0.506	0.22
1445_W	1449_T	0.506	0.22
409_L	440_Q	0.506	0.22
1061_G	1073_V	0.506	0.22
87_F	90_P	0.506	0.22
405_L	666_Q	0.506	0.22
1033_S	1597_R	0.506	0.22
1044_T	1555_L	0.506	0.22
1526_S	1621_P	0.506	0.22
563_L	1314_L	0.506	0.22
114_A	126_L	0.506	0.22
455_N	564_D	0.506	0.22
1083_L	1623_T	0.506	0.22
1095_D	1466_L	0.506	0.22
239_R	789_V	0.505	0.22
469_D	905_N	0.505	0.22
1243_W	1425_T	0.505	0.22
199_F	424_L	0.505	0.22
396_L	991_D	0.505	0.22
895_L	899_V	0.505	0.22
783_G	1124_R	0.505	0.22
1436_R	1439_Q	0.505	0.22
591_S	599_P	0.504	0.22
1261_L	1551_L	0.504	0.22
488_A	1050_P	0.504	0.22
783_G	902_G	0.504	0.22
103_V	142_E	0.504	0.22
652_Y	825_L	0.504	0.22
356_R	361_T	0.504	0.22
270_A	807_G	0.503	0.22
895_L	898_A	0.503	0.22
643_G	979_E	0.503	0.22
497_P	1477_S	0.503	0.22
1361_E	1368_K	0.503	0.22
594_E	1550_L	0.503	0.22
825_L	909_Y	0.503	0.22
324_L	342_V	0.502	0.22
1075_L	1078_G	0.502	0.22
1144_W	1374_D	0.502	0.22
991_D	996_L	0.502	0.22
340_G	567_G	0.502	0.22
163_D	247_N	0.502	0.22
194_N	923_R	0.501	0.22
514_Y	1018_A	0.501	0.22
387_Q	1317_A	0.501	0.22
932_Y	938_G	0.501	0.22
1176_Y	1422_W	0.501	0.22
512_Y	1042_D	0.501	0.22
866_P	1169_P	0.501	0.22
1530_V	1553_A	0.501	0.22
757_R	1424_S	0.500	0.22
1622_G	1634_M	0.500	0.22
97_F	118_S	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

Generate restraints

MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSENASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIHVVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTITTRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRNSLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAGRYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQATSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFGPRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTWPLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSVVGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDKGRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWWQEIDVRAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDENRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVVQQALPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRFMASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAIPADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNSDERIWLGDYGSSLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAARTIQDLPGKWQAQTSFSAEQLTGEKAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYPQSAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLPAGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPVTLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP

To renumber constraints, replace the sequence above. use hmmalign

Type: Prob:
Scale the weights by the probability

Make symmetric:
List chains interacting with chain A.

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3prxB	1	0.5723	100	0.566	Contact Map
2hr0B	1	0.4077	100	0.733	Contact Map
4fxkB	1	0.363	100	0.78	Contact Map
4fxkA	1	0.363	100	0.818	Contact Map
2hr0A	1	0.3612	100	0.823	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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