GREMLIN Database
PBPC - Penicillin-binding protein 1C
UniProt: P76577 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14210
Length: 770 (607)
Sequences: 5045 (3645)
Seq/√Len: 147.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
183_K192_E5.0711.00
174_G184_S4.6821.00
234_R238_K4.4821.00
449_A533_G4.0421.00
233_S236_Q3.9361.00
524_I533_G3.7031.00
227_A237_V3.6831.00
305_V532_I3.4881.00
74_P78_E3.3661.00
387_I397_L3.3441.00
305_V560_V3.2161.00
259_F275_T3.1571.00
76_Y173_I3.1341.00
216_E220_N3.0111.00
460_K476_P2.8711.00
288_A301_L2.8081.00
487_R526_V2.7741.00
174_G185_P2.7371.00
227_A234_R2.7341.00
98_S101_R2.6711.00
308_H531_V2.6631.00
89_W154_R2.6211.00
29_D32_W2.5881.00
47_A51_T2.5821.00
87_W95_N2.5611.00
48_Q277_D2.5551.00
152_S155_E2.5151.00
78_E231_V2.4761.00
46_V271_K2.4081.00
237_V241_R2.4041.00
74_P77_L2.3751.00
191_S243_E2.3491.00
69_I77_L2.3461.00
307_D310_D2.3211.00
355_E412_R2.3151.00
69_I154_R2.2761.00
75_R78_E2.2301.00
303_M560_V2.2191.00
313_V466_L2.2141.00
360_P485_I2.1981.00
68_T71_D2.1871.00
224_E241_R2.1851.00
190_Y232_W2.1321.00
312_R465_R2.1251.00
83_Y221_K2.1221.00
488_R491_A2.1011.00
450_A464_L2.0931.00
73_S185_P2.0711.00
44_V52_P2.0601.00
314_R530_Y2.0291.00
307_D314_R2.0271.00
450_A461_A2.0211.00
304_I445_L2.0181.00
69_I158_T1.9941.00
76_Y193_A1.9741.00
86_R225_R1.9671.00
75_R193_A1.9421.00
481_G579_S1.9421.00
445_L533_G1.9401.00
80_L166_F1.9371.00
340_P443_A1.9371.00
77_L154_R1.9271.00
391_E395_R1.9211.00
360_P489_I1.9151.00
202_A205_R1.8961.00
28_A31_L1.8881.00
390_S488_R1.8731.00
105_Q114_S1.8691.00
328_F331_V1.8661.00
170_L179_A1.8561.00
46_V273_T1.8551.00
284_L303_M1.8531.00
225_R228_V1.8351.00
390_S492_D1.8091.00
290_N559_Q1.8081.00
71_D186_A1.8041.00
91_H148_E1.8031.00
44_V271_K1.7951.00
344_L417_L1.7791.00
565_L568_S1.7741.00
195_M215_A1.7631.00
280_L564_L1.7631.00
48_Q314_R1.7611.00
80_L197_A1.7181.00
81_I89_W1.7161.00
405_L413_F1.7141.00
347_F451_A1.7061.00
82_N231_V1.7021.00
455_F486_I1.7001.00
307_D312_R1.7001.00
484_W607_W1.6921.00
304_I446_E1.6861.00
280_L314_R1.6731.00
101_R114_S1.6501.00
508_L527_N1.6471.00
448_M524_I1.6461.00
224_E237_V1.6371.00
415_A419_N1.6271.00
510_W523_A1.6221.00
164_A200_P1.6201.00
262_M466_L1.6191.00
509_A526_V1.6141.00
332_D539_P1.6101.00
351_L416_K1.6071.00
389_M404_V1.5931.00
77_L89_W1.5921.00
190_Y240_S1.5891.00
380_D384_H1.5871.00
86_R229_Q1.5861.00
82_N229_Q1.5841.00
263_M274_T1.5781.00
303_M532_I1.5761.00
189_S243_E1.5751.00
484_W577_P1.5701.00
67_V72_V1.5641.00
69_I89_W1.5541.00
69_I72_V1.5431.00
124_A147_L1.5381.00
165_P169_T1.5351.00
178_W182_G1.5301.00
363_L386_P1.5291.00
350_G455_F1.5271.00
76_Y80_L1.5251.00
558_N562_N1.5211.00
394_V492_D1.5171.00
353_L489_I1.5061.00
350_G478_M1.5021.00
283_R563_I1.5001.00
282_R286_E1.4971.00
507_P570_N1.4931.00
329_G333_M1.4911.00
348_V437_I1.4871.00
225_R229_Q1.4791.00
618_L621_E1.4771.00
184_S187_N1.4731.00
557_L561_N1.4701.00
384_H397_L1.4691.00
379_F548_F1.4691.00
109_S113_I1.4661.00
309_T529_R1.4621.00
22_F26_W1.4581.00
445_L449_A1.4551.00
223_L237_V1.4551.00
259_F276_L1.4491.00
67_V185_P1.4491.00
227_A232_W1.4451.00
532_I560_V1.4421.00
306_V449_A1.4331.00
155_E158_T1.4311.00
476_P480_S1.4281.00
343_V448_M1.4241.00
405_L410_P1.4191.00
406_E434_L1.4181.00
28_A32_W1.4131.00
499_D502_L1.4061.00
83_Y225_R1.3711.00
286_E290_N1.3701.00
261_R264_L1.3671.00
529_R572_P1.3661.00
350_G482_A1.3651.00
347_F417_L1.3611.00
478_M483_A1.3541.00
283_R287_L1.3491.00
48_Q312_R1.3411.00
392_A400_P1.3401.00
353_L485_I1.3401.00
520_D535_W1.3391.00
563_I566_S1.3391.00
235_E239_E1.3381.00
188_L193_A1.3371.00
507_P573_E1.3351.00
346_P455_F1.3331.00
51_T278_A1.3281.00
350_G486_I1.3261.00
330_H333_M1.3251.00
286_E563_I1.3221.00
354_D419_N1.3221.00
338_R520_D1.3201.00
377_G381_S1.3171.00
151_L159_L1.3121.00
45_V56_F1.3081.00
213_E217_A1.3001.00
72_V76_Y1.2961.00
354_D482_A1.2881.00
457_R462_G1.2831.00
389_M489_I1.2831.00
234_R237_V1.2741.00
134_F138_I1.2741.00
79_A226_M1.2721.00
458_H484_W1.2701.00
453_T531_V1.2681.00
424_L447_D1.2661.00
481_G580_V1.2631.00
364_L407_A1.2601.00
306_V531_V1.2601.00
420_V478_M1.2591.00
354_D416_K1.2591.00
166_F173_I1.2541.00
412_R415_A1.2501.00
397_L400_P1.2471.00
262_M266_K1.2451.00
236_Q239_E1.2411.00
536_T556_L1.2381.00
288_A303_M1.2351.00
95_N98_S1.2331.00
391_E394_V1.2301.00
75_R236_Q1.2141.00
94_V141_L1.2061.00
492_D496_P1.2041.00
112_V132_K1.2011.00
352_A404_V1.2001.00
227_A241_R1.2001.00
354_D479_S1.1991.00
303_M534_I1.1961.00
123_V159_L1.1951.00
52_P55_R1.1941.00
487_R509_A1.1931.00
284_L560_V1.1911.00
455_F526_V1.1901.00
399_L403_Q1.1881.00
87_W90_K1.1861.00
220_N241_R1.1851.00
350_G416_K1.1841.00
420_V454_A1.1831.00
458_H480_S1.1801.00
135_G139_R1.1801.00
525_G557_L1.1791.00
285_E289_Q1.1761.00
494_A508_L1.1731.00
285_E317_V1.1721.00
69_I157_L1.1671.00
387_I400_P1.1671.00
80_L200_P1.1661.00
211_W214_R1.1651.00
79_A197_A1.1641.00
116_G125_R1.1621.00
532_I561_N1.1621.00
148_E156_I1.1531.00
608_L614_P1.1521.00
100_A103_A1.1511.00
191_S240_S1.1501.00
471_P474_E1.1451.00
238_K242_E1.1441.00
280_L315_G1.1431.00
287_L559_Q1.1391.00
291_W556_L1.1381.00
224_E228_V1.1371.00
190_Y223_L1.1360.99
508_L557_L1.1360.99
374_Y402_V1.1320.99
161_L173_I1.1270.99
191_S219_R1.1270.99
329_G332_D1.1260.99
85_D91_H1.1250.99
87_W91_H1.1240.99
68_T158_T1.1230.99
43_R272_I1.1220.99
75_R190_Y1.1180.99
405_L436_L1.1180.99
146_Q149_W1.1160.99
495_Q503_P1.1020.99
416_K420_V1.0960.99
387_I392_A1.0960.99
586_C618_L1.0890.99
284_L317_V1.0880.99
506_A529_R1.0870.99
401_A404_V1.0860.99
308_H530_Y1.0820.99
419_N475_R1.0820.99
99_V116_G1.0810.99
165_P171_Q1.0800.99
109_S112_V1.0790.99
23_L27_G1.0740.99
456_A526_V1.0710.99
461_A475_R1.0670.99
411_K415_A1.0670.99
47_A278_A1.0640.99
270_D472_L1.0630.99
99_V121_M1.0610.99
348_V413_F1.0610.99
399_L402_V1.0600.99
364_L400_P1.0590.99
168_G207_R1.0580.99
120_T148_E1.0580.99
280_L560_V1.0570.99
288_A317_V1.0550.99
484_W576_R1.0540.99
380_D397_L1.0540.99
45_V53_L1.0520.99
106_D134_F1.0510.99
370_R375_R1.0500.99
224_E227_A1.0490.99
383_F399_L1.0480.99
77_L157_L1.0460.99
370_R373_D1.0440.99
411_K432_P1.0400.99
106_D116_G1.0380.99
361_A608_L1.0330.99
72_V77_L1.0320.99
66_P158_T1.0280.99
262_M265_G1.0280.99
239_E243_E1.0280.99
212_P216_E1.0250.99
119_L164_A1.0250.99
350_G483_A1.0250.99
284_L315_G1.0250.99
146_Q150_H1.0240.99
100_A104_W1.0230.99
216_E219_R1.0220.99
609_L612_S1.0210.99
227_A238_K1.0200.99
125_R130_H1.0190.99
435_S440_G1.0180.99
304_I449_A1.0170.99
301_L556_L1.0170.99
491_A573_E1.0170.99
103_A106_D1.0160.99
528_A574_D1.0140.99
590_G593_L1.0140.99
106_D112_V1.0120.99
367_V403_Q1.0100.99
308_H456_A1.0070.99
104_W108_T1.0050.99
76_Y161_L1.0040.99
365_Q386_P1.0030.99
347_F420_V1.0030.99
582_R607_W0.9970.99
326_S329_G0.9930.99
183_K187_N0.9910.99
483_A487_R0.9880.99
202_A206_L0.9880.99
106_D109_S0.9880.99
340_P440_G0.9870.99
173_I196_L0.9860.99
306_V464_L0.9850.99
402_V438_L0.9800.99
214_R217_A0.9800.99
491_A507_P0.9790.98
353_L486_I0.9790.98
444_K447_D0.9780.98
530_Y564_L0.9780.98
449_A524_I0.9720.98
366_D385_G0.9720.98
506_A570_N0.9680.98
238_K241_R0.9680.98
134_F141_L0.9660.98
576_R582_R0.9640.98
364_L404_V0.9630.98
585_I606_T0.9630.98
112_V134_F0.9630.98
349_Y401_A0.9570.98
422_L443_A0.9550.98
198_V215_A0.9480.98
394_V496_P0.9480.98
405_L437_I0.9480.98
262_M316_W0.9460.98
8_R12_I0.9460.98
608_L611_G0.9440.98
87_W97_F0.9400.98
96_P99_V0.9390.98
343_V524_I0.9370.98
340_P344_L0.9360.98
121_M140_Q0.9340.98
536_T553_A0.9340.98
487_R490_M0.9300.98
344_L348_V0.9280.98
519_R541_G0.9230.98
124_A127_L0.9200.98
416_K478_M0.9200.98
584_V603_R0.9200.98
83_Y201_Q0.9190.98
340_P442_G0.9180.98
275_T312_R0.9180.98
27_G32_W0.9160.98
416_K419_N0.9130.98
278_A282_R0.9100.98
500_S503_P0.9080.98
96_P100_A0.9050.97
308_H453_T0.9030.97
277_D280_L0.9030.97
81_I231_V0.8990.97
586_C600_C0.8980.97
591_Q616_T0.8980.97
494_A523_A0.8980.97
480_S579_S0.8950.97
305_V530_Y0.8950.97
445_L524_I0.8900.97
316_W466_L0.8900.97
185_P188_L0.8860.97
506_A565_L0.8830.97
80_L161_L0.8830.97
499_D523_A0.8820.97
384_H387_I0.8820.97
49_D278_A0.8780.97
609_L613_Q0.8770.97
304_I316_W0.8770.97
493_E499_D0.8760.97
393_L401_A0.8760.97
81_I157_L0.8730.97
339_S515_S0.8710.97
599_N603_R0.8640.97
586_C590_G0.8620.97
504_R507_P0.8620.97
310_D465_R0.8610.97
195_M219_R0.8600.97
261_R322_L0.8590.97
521_A549_G0.8580.97
350_G420_V0.8550.96
550_F554_V0.8550.96
168_G179_A0.8550.96
364_L389_M0.8540.96
483_A486_I0.8510.96
205_R214_R0.8510.96
328_F332_D0.8490.96
384_H395_R0.8490.96
92_P96_P0.8480.96
449_A531_V0.8460.96
219_R244_P0.8450.96
340_P441_A0.8450.96
80_L164_A0.8440.96
586_C589_G0.8420.96
65_Y174_G0.8420.96
46_V52_P0.8410.96
408_Y413_F0.8370.96
521_A547_Q0.8360.96
80_L173_I0.8320.96
259_F466_L0.8310.96
44_V55_R0.8310.96
174_G178_W0.8290.96
490_M526_V0.8260.96
606_T609_L0.8260.96
106_D141_L0.8240.96
598_G601_R0.8230.96
89_W157_L0.8220.96
157_L161_L0.8220.96
520_D537_G0.8220.96
408_Y412_R0.8210.96
326_S331_V0.8210.96
588_P602_R0.8210.96
99_V141_L0.8200.96
485_I580_V0.8200.96
78_E89_W0.8180.95
94_V145_L0.8170.95
422_L451_A0.8160.95
213_E216_E0.8150.95
148_E153_K0.8140.95
182_G248_A0.8120.95
390_S606_T0.8120.95
479_S482_A0.8110.95
185_P193_A0.8100.95
72_V173_I0.8100.95
73_S193_A0.8080.95
195_M198_V0.8080.95
521_A553_A0.8060.95
71_D174_G0.8060.95
105_Q113_I0.8060.95
561_N565_L0.8050.95
83_Y218_A0.8040.95
182_G250_R0.8030.95
112_V116_G0.8010.95
455_F478_M0.8010.95
41_P66_P0.8010.95
454_A461_A0.8010.95
138_I142_W0.7990.95
305_V564_L0.7960.95
393_L489_I0.7960.95
353_L482_A0.7950.95
235_E238_K0.7930.95
585_I593_L0.7920.95
377_G383_F0.7920.95
258_L319_S0.7910.95
409_G412_R0.7890.94
526_V561_N0.7880.94
366_D383_F0.7880.94
366_D384_H0.7850.94
491_A495_Q0.7840.94
80_L119_L0.7840.94
76_Y190_Y0.7810.94
177_S181_L0.7800.94
502_L554_V0.7790.94
414_A418_R0.7770.94
232_W237_V0.7770.94
65_Y178_W0.7720.94
106_D114_S0.7720.94
105_Q109_S0.7690.94
56_F264_L0.7680.94
113_I132_K0.7670.94
589_G592_S0.7660.94
83_Y229_Q0.7660.94
585_I590_G0.7650.94
417_L422_L0.7650.94
165_P170_L0.7630.93
357_L407_A0.7620.93
280_L305_V0.7600.93
330_H336_S0.7600.93
25_A28_A0.7600.93
608_L612_S0.7590.93
584_V605_A0.7570.93
340_P448_M0.7540.93
583_G592_S0.7540.93
582_R605_A0.7530.93
201_Q205_R0.7530.93
600_C618_L0.7520.93
51_T279_G0.7500.93
482_A486_I0.7500.93
73_S76_Y0.7480.93
69_I73_S0.7480.93
167_G180_Y0.7480.93
602_R606_T0.7480.93
604_L608_L0.7460.93
487_R574_D0.7460.93
443_A448_M0.7440.93
113_I116_G0.7430.93
493_E523_A0.7430.93
405_L434_L0.7420.92
559_Q563_I0.7420.92
579_S610_D0.7420.92
313_V446_E0.7410.92
534_I556_L0.7410.92
509_A574_D0.7390.92
67_V174_G0.7380.92
388_S391_E0.7380.92
455_F487_R0.7380.92
581_T613_Q0.7370.92
600_C604_L0.7370.92
357_L404_V0.7370.92
30_K33_P0.7350.92
523_A557_L0.7350.92
431_A441_A0.7340.92
479_S483_A0.7330.92
128_D131_P0.7330.92
529_R568_S0.7320.92
422_L448_M0.7320.92
76_Y185_P0.7320.92
128_D136_G0.7290.92
67_V73_S0.7290.92
9_G16_A0.7260.92
534_I553_A0.7250.92
94_V99_V0.7250.92
494_A510_W0.7240.92
577_P580_V0.7240.92
484_W580_V0.7230.91
450_A453_T0.7220.91
478_M482_A0.7210.91
304_I531_V0.7210.91
12_I16_A0.7180.91
351_L408_Y0.7180.91
606_T611_G0.7160.91
120_T144_A0.7160.91
492_D495_Q0.7150.91
77_L81_I0.7130.91
347_F448_M0.7120.91
583_G613_Q0.7110.91
363_L388_S0.7110.91
589_G618_L0.7100.91
601_R605_A0.7100.91
521_A550_F0.7100.91
348_V405_L0.7080.91
174_G177_S0.7070.91
233_S237_V0.7060.91
415_A418_R0.7060.91
98_S114_S0.7030.90
201_Q206_L0.7030.90
302_A445_L0.7020.90
121_M128_D0.7010.90
198_V222_V0.7000.90
23_L26_W0.6990.90
368_P383_F0.6990.90
275_T465_R0.6960.90
369_R406_E0.6960.90
232_W240_S0.6950.90
201_Q221_K0.6950.90
201_Q222_V0.6950.90
178_W184_S0.6950.90
359_H362_S0.6930.90
615_P619_L0.6920.90
576_R580_V0.6890.89
262_M313_V0.6890.89
418_R423_P0.6880.89
189_S193_A0.6870.89
362_S404_V0.6850.89
10_C14_L0.6840.89
21_L26_W0.6840.89
326_S330_H0.6840.89
621_E624_G0.6830.89
72_V75_R0.6830.89
331_V334_V0.6820.89
18_P26_W0.6820.89
327_R330_H0.6820.89
366_D397_L0.6810.89
445_L522_W0.6810.89
106_D110_G0.6800.89
351_L413_F0.6790.89
319_S332_D0.6790.89
506_A569_A0.6780.89
493_E510_W0.6760.89
608_L613_Q0.6760.89
243_E247_L0.6760.89
613_Q617_L0.6750.88
337_I447_D0.6740.88
280_L283_R0.6730.88
349_Y393_L0.6730.88
364_L403_Q0.6720.88
59_A64_R0.6720.88
619_L624_G0.6720.88
195_M209_D0.6710.88
494_A499_D0.6710.88
482_A609_L0.6700.88
560_V564_L0.6690.88
125_R132_K0.6690.88
621_E625_I0.6680.88
340_P343_V0.6670.88
328_F333_M0.6670.88
28_A33_P0.6660.88
420_V451_A0.6660.88
243_E246_W0.6660.88
606_T614_P0.6650.88
282_R285_E0.6640.88
244_P247_L0.6640.88
423_P447_D0.6610.87
21_L25_A0.6600.87
496_P500_S0.6600.87
611_G617_L0.6590.87
190_Y193_A0.6580.87
266_K465_R0.6570.87
600_C603_R0.6570.87
102_A106_D0.6560.87
96_P145_L0.6560.87
450_A463_K0.6550.87
11_W14_L0.6540.87
8_R15_A0.6540.87
221_K224_E0.6530.87
57_A60_D0.6520.87
591_Q619_L0.6520.87
221_K225_R0.6510.87
458_H575_P0.6510.87
414_A436_L0.6500.87
240_S243_E0.6480.86
486_I489_I0.6480.86
168_G209_D0.6460.86
490_M493_E0.6460.86
488_R492_D0.6460.86
26_W29_D0.6450.86
581_T610_D0.6440.86
193_A200_P0.6440.86
232_W236_Q0.6430.86
414_A432_P0.6420.86
227_A230_G0.6400.86
279_G283_R0.6390.86
387_I391_E0.6390.86
114_S132_K0.6380.86
101_R105_Q0.6380.86
50_G273_T0.6380.86
528_A572_P0.6370.85
456_A509_A0.6370.85
330_H539_P0.6370.85
279_G567_R0.6370.85
412_R416_K0.6350.85
454_A477_L0.6350.85
364_L387_I0.6350.85
425_Y447_D0.6350.85
327_R331_V0.6350.85
521_A552_S0.6340.85
593_L603_R0.6330.85
501_A554_V0.6330.85
454_A478_M0.6330.85
590_G608_L0.6330.85
309_T572_P0.6320.85
195_M245_I0.6310.85
166_F200_P0.6310.85
286_E289_Q0.6310.85
181_L245_I0.6290.85
236_Q240_S0.6290.85
461_A464_L0.6290.85
518_Y521_A0.6290.85
257_P260_S0.6280.85
313_V316_W0.6280.85
177_S188_L0.6270.85
315_G560_V0.6270.85
433_N440_G0.6250.84
125_R136_G0.6240.84
319_S539_P0.6230.84
197_A200_P0.6210.84
619_L623_E0.6200.84
521_A536_T0.6200.84
20_L24_A0.6190.84
29_D33_P0.6190.84
196_L200_P0.6180.84
258_L300_S0.6170.84
404_V408_Y0.6170.84
594_P618_L0.6160.83
53_L276_L0.6150.83
618_L624_G0.6140.83
99_V106_D0.6120.83
54_W260_S0.6120.83
590_G614_P0.6110.83
378_N383_F0.6100.83
316_W332_D0.6080.83
549_G553_A0.6080.83
393_L486_I0.6070.83
610_D613_Q0.6060.82
306_V453_T0.6050.82
106_D132_K0.6050.82
532_I557_L0.6050.82
151_L155_E0.6040.82
195_M212_P0.6040.82
199_L202_A0.6040.82
374_Y434_L0.6030.82
353_L360_P0.6010.82
603_R608_L0.6010.82
525_G561_N0.6000.82
69_I81_I0.5990.82
589_G608_L0.5980.82
81_I86_R0.5980.82
21_L24_A0.5980.82
53_L278_A0.5970.82
618_L622_Q0.5970.82
369_R403_Q0.5960.81
530_Y565_L0.5950.81
207_R210_R0.5950.81
337_I442_G0.5940.81
92_P145_L0.5940.81
105_Q112_V0.5940.81
586_C621_E0.5940.81
73_S77_L0.5890.81
344_L347_F0.5890.81
131_P136_G0.5880.81
598_G602_R0.5880.81
506_A528_A0.5870.80
105_Q108_T0.5860.80
73_S186_A0.5860.80
446_E466_L0.5850.80
590_G594_P0.5840.80
174_G186_A0.5840.80
359_H612_S0.5840.80
617_L621_E0.5830.80
16_A19_F0.5820.80
519_R540_D0.5800.80
128_D143_R0.5800.80
49_D277_D0.5790.80
76_Y188_L0.5790.80
17_A23_L0.5780.79
585_I589_G0.5780.79
116_G132_K0.5780.79
592_S614_P0.5770.79
106_D111_R0.5750.79
527_N574_D0.5740.79
338_R535_W0.5740.79
410_P432_P0.5740.79
46_V50_G0.5730.79
67_V71_D0.5710.79
607_W611_G0.5690.78
21_L27_G0.5690.78
216_E245_I0.5690.78
365_Q403_Q0.5670.78
593_L598_G0.5660.78
566_S569_A0.5650.78
615_P623_E0.5650.78
527_N565_L0.5650.78
494_A502_L0.5640.78
262_M334_V0.5620.78
287_L563_I0.5600.77
20_L23_L0.5600.77
401_A489_I0.5600.77
564_L567_R0.5600.77
83_Y222_V0.5590.77
328_F335_N0.5580.77
585_I608_L0.5570.77
16_A20_L0.5570.77
92_P148_E0.5570.77
346_P393_L0.5570.77
612_S618_L0.5570.77
612_S615_P0.5560.77
446_E449_A0.5560.77
24_A28_A0.5550.77
611_G615_P0.5550.77
265_G335_N0.5550.77
170_L204_S0.5540.77
440_G515_S0.5540.77
121_M136_G0.5530.76
339_S516_Y0.5530.76
591_Q594_P0.5500.76
42_A55_R0.5500.76
554_V558_N0.5490.76
177_S193_A0.5490.76
448_M522_W0.5480.76
261_R265_G0.5480.76
256_A282_R0.5480.76
13_T16_A0.5480.76
103_A108_T0.5470.76
266_K466_L0.5470.76
300_S539_P0.5470.76
309_T457_R0.5460.76
101_R225_R0.5450.75
515_S520_D0.5450.75
256_A259_F0.5450.75
195_M208_P0.5430.75
15_A19_F0.5420.75
124_A143_R0.5420.75
502_L558_N0.5420.75
594_P599_N0.5420.75
19_F22_F0.5410.75
619_L622_Q0.5410.75
394_V493_E0.5410.75
281_Q316_W0.5410.75
476_P479_S0.5400.75
611_G614_P0.5400.75
192_E243_E0.5400.75
457_R460_K0.5390.75
198_V221_K0.5390.75
65_Y175_A0.5390.75
587_W604_L0.5370.74
536_T550_F0.5360.74
302_A535_W0.5360.74
371_T434_L0.5360.74
515_S541_G0.5350.74
259_F263_M0.5350.74
589_G593_L0.5350.74
284_L305_V0.5350.74
593_L599_N0.5340.74
27_G138_I0.5340.74
121_M125_R0.5340.74
300_S332_D0.5340.74
173_I185_P0.5340.74
41_P467_Q0.5340.74
87_W148_E0.5340.74
423_P426_L0.5330.74
588_P591_Q0.5330.74
548_F551_A0.5330.74
211_W215_A0.5330.74
212_P247_L0.5330.74
78_E154_R0.5320.74
509_A561_N0.5310.73
219_R247_L0.5300.73
493_E498_P0.5290.73
300_S320_V0.5290.73
491_A494_A0.5290.73
245_I248_A0.5290.73
72_V158_T0.5280.73
622_Q625_I0.5270.73
360_P606_T0.5260.73
308_H528_A0.5260.73
121_M141_L0.5260.73
605_A609_L0.5250.73
435_S442_G0.5250.73
165_P168_G0.5250.73
484_W579_S0.5240.73
353_L389_M0.5240.73
550_F553_A0.5230.72
179_A199_L0.5230.72
307_D529_R0.5230.72
177_S196_L0.5220.72
260_S264_L0.5220.72
400_P403_Q0.5220.72
436_L441_A0.5210.72
291_W559_Q0.5210.72
277_D314_R0.5200.72
48_Q278_A0.5200.72
401_A437_I0.5190.72
216_E244_P0.5180.72
24_A27_G0.5180.72
204_S211_W0.5180.72
18_P22_F0.5170.72
371_T376_P0.5160.71
103_A107_L0.5160.71
529_R565_L0.5160.71
302_A332_D0.5160.71
366_D400_P0.5160.71
277_D568_S0.5150.71
67_V173_I0.5150.71
422_L426_L0.5150.71
47_A50_G0.5150.71
433_N442_G0.5140.71
561_N564_L0.5140.71
371_T392_A0.5140.71
601_R606_T0.5130.71
493_E497_L0.5130.71
593_L600_C0.5130.71
534_I557_L0.5120.71
13_T17_A0.5120.71
287_L556_L0.5110.71
219_R245_I0.5110.71
226_M232_W0.5110.71
452_Y524_I0.5100.71
526_V531_V0.5100.71
177_S185_P0.5100.71
389_M400_P0.5090.70
26_W32_W0.5090.70
316_W334_V0.5080.70
614_P621_E0.5080.70
586_C592_S0.5080.70
64_R269_S0.5070.70
456_A487_R0.5070.70
461_A477_L0.5070.70
202_A214_R0.5070.70
218_A226_M0.5060.70
547_Q552_S0.5060.70
339_S440_G0.5030.69
47_A53_L0.5030.69
283_R286_E0.5030.69
283_R564_L0.5030.69
422_L447_D0.5020.69
515_S519_R0.5020.69
376_P402_V0.5020.69
546_G550_F0.5020.69
587_W602_R0.5020.69
288_A556_L0.5010.69
344_L441_A0.5000.69
233_S240_S0.5000.69
344_L413_F0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oonA 1 0.4649 100 0.229 Contact Map
2jchA 1 0.513 100 0.265 Contact Map
3vmaA 1 0.7584 100 0.269 Contact Map
3udfA 2 0.6 100 0.284 Contact Map
2olvA 1 0.713 100 0.326 Contact Map
3zg9B 1 0.5325 100 0.474 Contact Map
2y2mA 2 0.5649 100 0.602 Contact Map
3un7A 1 0.4351 100 0.67 Contact Map
2v2fF 1 0.4221 100 0.674 Contact Map
2oqoA 2 0.2338 100 0.674 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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