GREMLIN Database
YFGJ - Uncharacterized protein YfgJ
UniProt: P76575 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14206
Length: 71 (68)
Sequences: 161 (94)
Seq/√Len: 11.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_D65_R2.5830.89
20_R27_F2.5760.89
38_H67_E2.2900.82
15_D27_F2.0830.76
3_L30_M1.8910.68
50_V64_K1.8120.65
4_H25_G1.7260.61
23_S56_H1.6390.57
32_A63_K1.6050.55
57_G64_K1.5860.54
13_D22_R1.5750.54
43_V60_L1.5570.53
9_Q26_E1.5520.52
51_D64_K1.4870.49
33_L42_Q1.4720.48
13_D27_F1.4680.48
12_L53_F1.4310.46
39_Q67_E1.4230.46
12_L30_M1.4050.45
3_L19_A1.4010.45
26_E31_K1.3870.44
27_F31_K1.3720.44
14_Q19_A1.3060.40
41_L66_V1.2960.40
7_Q22_R1.2870.40
4_H9_Q1.2760.39
42_Q68_F1.2330.37
15_D18_H1.2170.36
7_Q26_E1.2130.36
10_H23_S1.1940.35
39_Q64_K1.1680.34
19_A30_M1.1640.34
12_L15_D1.1550.34
39_Q56_H1.1230.32
7_Q25_G1.1100.32
14_Q30_M1.0690.30
36_D52_Y1.0550.29
9_Q27_F0.9950.27
58_H61_I0.9740.26
32_A51_D0.9550.25
3_L10_H0.9490.25
10_H39_Q0.9440.25
50_V63_K0.9330.25
5_C8_C0.9320.25
7_Q27_F0.9320.25
55_Q59_G0.9310.25
4_H23_S0.9140.24
57_G61_I0.9050.24
45_K50_V0.8960.23
2_E29_E0.8870.23
14_Q17_G0.8850.23
13_D20_R0.8680.22
23_S28_I0.8430.22
9_Q15_D0.8300.21
14_Q18_H0.8230.21
9_Q55_Q0.8180.21
4_H11_V0.8080.20
4_H26_E0.8040.20
14_Q43_V0.7970.20
45_K61_I0.7870.20
10_H18_H0.7700.19
33_L63_K0.7700.19
12_L25_G0.7560.19
3_L12_L0.7500.19
50_V68_F0.7490.19
22_R25_G0.7480.19
13_D19_A0.7440.18
18_H26_E0.7350.18
19_A53_F0.7280.18
43_V59_G0.6890.17
22_R49_A0.6870.17
18_H31_K0.6860.17
6_P62_S0.6820.17
9_Q68_F0.6710.16
64_K67_E0.6680.16
2_E7_Q0.6550.16
19_A33_L0.6530.16
31_K63_K0.6480.16
11_V28_I0.6480.16
59_G64_K0.6450.16
20_R25_G0.6420.16
4_H12_L0.6400.16
55_Q58_H0.6130.15
50_V55_Q0.6130.15
51_D61_I0.6130.15
17_G68_F0.6050.15
15_D25_G0.6010.15
16_N31_K0.5990.15
50_V61_I0.5840.14
16_N53_F0.5810.14
7_Q13_D0.5650.14
35_P65_R0.5390.13
4_H31_K0.5340.13
25_G69_V0.5280.13
38_H56_H0.5150.13
3_L14_Q0.5120.13
2_E27_F0.5100.13
6_P46_A0.5080.12
30_M43_V0.5080.12
23_S29_E0.5030.12
29_E40_P0.5030.12
6_P25_G0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jneA 1 1 100 0.088 Contact Map
2jrpA 1 1 100 0.131 Contact Map
3wwlA 1 0.6338 87.2 0.866 Contact Map
4cgyA 1 0 72.5 0.884 Contact Map
3mpxA 1 0 70.3 0.887 Contact Map
3vk6A 2 0.9859 70.1 0.887 Contact Map
2f42A 2 0.7042 69.8 0.887 Contact Map
3pmqA 1 0.9296 69.4 0.887 Contact Map
5aieA 1 0.5915 68 0.888 Contact Map
1qo8A 2 0.9014 65.7 0.89 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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