TMCA - ECOLI - GREMLIN Contacts

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TMCA - tRNA(Met) cytidine acetyltransferase TmcA

UniProt:	P76562	Sequences: MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFEHTLKLRDALPGDWLWISPRPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWLVLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNEAILWRQNQPFSLAHFTPRTDWYPATGAPQPEQQQLLKQLMTMPPGVAAVTAARGRGKSALAGQLISRIAGRAIVTAPAKASTDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLVSRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEALVFDDENFTHTPQGNIVISAFEQTLWQSDPETPLKVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQAAGENEIAGALWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGNNPLAATLRGRRVSRIAVHPARQREGTGRQLIAGALQYTQDLDYLSVSFGYTGELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGETLPVDPLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQLCTTLKLSGRKMLLVRQREEAAQALFALNDVRTERLRDRITQWQLFH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14196
Length:	671 (635)
Sequences:	786 (546)
Seq/√Len:	21.7

ECOLI - TMCA
HALSA - Q9HQH9
SULSO - Q97U12 Q980C5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
492_V	529_A	7.818	1.00
184_L	208_L	7.651	1.00
407_G	463_V	6.470	1.00
399_A	472_T	6.346	1.00
481_L	531_L	5.983	1.00
84_F	89_F	5.959	1.00
437_V	491_S	5.621	1.00
477_I	507_C	5.302	1.00
458_V	477_I	5.017	1.00
474_R	507_C	4.978	1.00
477_I	509_F	4.541	1.00
614_G	625_L	4.371	1.00
222_V	233_L	4.133	1.00
413_D	456_R	3.939	1.00
207_A	236_F	3.813	1.00
230_T	233_L	3.772	1.00
495_G	500_L	3.766	1.00
74_R	97_K	3.660	1.00
512_V	530_L	3.616	1.00
455_G	489_Y	3.505	1.00
261_V	284_L	3.451	1.00
213_I	260_V	3.354	1.00
465_P	468_Q	3.165	1.00
511_L	527_A	3.064	1.00
225_P	266_A	2.994	0.99
437_V	528_M	2.931	0.99
237_A	241_F	2.892	0.99
495_G	524_C	2.841	0.99
369_V	405_I	2.779	0.99
296_R	495_G	2.763	0.99
447_N	544_E	2.711	0.99
369_V	396_F	2.707	0.99
369_V	408_A	2.673	0.99
373_L	408_A	2.643	0.99
209_A	285_T	2.630	0.99
224_A	243_F	2.621	0.99
284_L	302_F	2.612	0.98
354_F	359_W	2.601	0.98
354_F	358_L	2.586	0.98
441_L	512_V	2.568	0.98
259_L	279_F	2.545	0.98
338_D	371_Q	2.542	0.98
259_L	275_L	2.489	0.98
620_A	628_T	2.423	0.97
547_R	580_E	2.410	0.97
369_V	388_M	2.378	0.97
117_D	386_R	2.367	0.97
436_L	493_S	2.354	0.97
26_S	405_I	2.350	0.97
455_G	491_S	2.227	0.96
440_S	513_R	2.217	0.96
399_A	407_G	2.209	0.96
394_Q	410_W	2.196	0.95
409_L	476_L	2.190	0.95
175_A	184_L	2.160	0.95
368_K	404_E	2.151	0.95
89_F	330_V	2.143	0.95
538_K	567_P	2.017	0.93
296_R	500_L	2.001	0.93
456_R	487_L	1.989	0.92
407_G	476_L	1.977	0.92
468_Q	473_G	1.965	0.92
633_G	642_R	1.956	0.92
488_D	534_S	1.935	0.91
184_L	211_Q	1.931	0.91
550_R	577_D	1.926	0.91
510_V	545_H	1.915	0.91
409_L	480_A	1.883	0.90
337_D	367_L	1.879	0.90
65_L	91_A	1.875	0.90
31_W	154_Q	1.864	0.89
225_P	267_I	1.862	0.89
614_G	620_A	1.851	0.89
286_T	298_F	1.839	0.89
84_F	391_A	1.821	0.88
359_W	389_M	1.806	0.88
591_L	615_R	1.806	0.88
379_R	519_E	1.789	0.87
213_I	233_L	1.788	0.87
296_R	302_F	1.778	0.87
87_A	383_L	1.774	0.87
90_A	334_L	1.768	0.87
207_A	232_V	1.745	0.86
84_F	368_K	1.729	0.86
179_E	315_Q	1.724	0.85
272_L	302_F	1.719	0.85
372_L	436_L	1.716	0.85
611_A	629_L	1.705	0.85
379_R	521_S	1.705	0.85
591_L	622_D	1.681	0.84
316_Q	322_Q	1.680	0.84
440_S	528_M	1.675	0.84
28_E	154_Q	1.670	0.83
525_Y	560_G	1.667	0.83
222_V	234_A	1.663	0.83
15_K	18_G	1.660	0.83
72_E	98_A	1.653	0.83
196_A	303_C	1.648	0.83
456_R	484_T	1.645	0.83
259_L	282_T	1.641	0.82
377_H	460_R	1.626	0.82
203_R	327_E	1.616	0.81
355_E	359_W	1.610	0.81
494_F	583_G	1.609	0.81
424_A	429_F	1.603	0.81
374_S	511_L	1.601	0.81
24_V	27_G	1.597	0.81
615_R	622_D	1.586	0.80
430_R	515_G	1.551	0.79
187_L	197_V	1.548	0.78
183_L	197_V	1.533	0.78
412_V	459_S	1.522	0.77
190_M	193_G	1.517	0.77
197_V	312_F	1.484	0.75
93_S	330_V	1.480	0.75
386_R	432_P	1.471	0.75
103_V	312_F	1.470	0.75
135_F	391_A	1.457	0.74
107_P	112_W	1.454	0.74
440_S	444_H	1.451	0.74
260_V	388_M	1.448	0.73
496_Y	501_W	1.443	0.73
20_R	27_G	1.442	0.73
407_G	603_Q	1.438	0.73
197_V	396_F	1.429	0.72
23_L	103_V	1.429	0.72
26_S	35_H	1.423	0.72
416_G	438_A	1.420	0.72
212_L	258_W	1.419	0.72
625_L	637_L	1.419	0.72
514_M	593_T	1.416	0.72
106_L	112_W	1.416	0.72
209_A	220_A	1.409	0.71
539_Q	604_T	1.403	0.71
230_T	285_T	1.399	0.71
186_Q	310_H	1.391	0.70
269_A	302_F	1.389	0.70
222_V	464_H	1.386	0.70
614_G	628_T	1.381	0.70
336_F	501_W	1.381	0.70
109_W	140_K	1.373	0.69
444_H	517_H	1.372	0.69
474_R	477_I	1.353	0.68
14_M	19_I	1.337	0.67
359_W	362_D	1.336	0.67
372_L	468_Q	1.333	0.67
74_R	100_S	1.333	0.67
25_L	103_V	1.324	0.66
136_V	198_T	1.322	0.66
437_V	455_G	1.321	0.66
556_A	620_A	1.314	0.66
64_A	229_S	1.309	0.66
411_L	456_R	1.306	0.65
60_C	219_R	1.302	0.65
614_G	629_L	1.300	0.65
14_M	18_G	1.299	0.65
403_N	546_Y	1.297	0.65
253_D	279_F	1.291	0.64
85_D	383_L	1.291	0.64
16_R	19_I	1.288	0.64
534_S	537_G	1.287	0.64
356_Q	359_W	1.286	0.64
297_G	302_F	1.281	0.64
329_M	333_A	1.272	0.63
84_F	425_V	1.267	0.63
286_T	649_L	1.259	0.62
269_A	526_T	1.255	0.62
197_V	514_M	1.242	0.61
336_F	548_L	1.235	0.61
275_L	279_F	1.234	0.61
552_A	560_G	1.233	0.61
76_A	284_L	1.231	0.61
574_S	624_Q	1.230	0.61
321_A	325_P	1.217	0.60
352_S	395_H	1.216	0.60
502_R	506_R	1.214	0.60
474_R	506_R	1.213	0.60
72_E	247_D	1.212	0.59
395_H	413_D	1.209	0.59
292_E	319_R	1.202	0.59
177_Q	388_M	1.192	0.58
318_I	374_S	1.188	0.58
35_H	530_L	1.188	0.58
476_L	480_A	1.187	0.58
612_L	637_L	1.187	0.58
17_E	22_L	1.185	0.58
254_E	259_L	1.177	0.57
96_L	102_L	1.177	0.57
223_T	226_A	1.175	0.57
379_R	455_G	1.171	0.57
15_K	19_I	1.170	0.57
481_L	509_F	1.165	0.56
573_L	577_D	1.162	0.56
138_H	142_V	1.162	0.56
197_V	564_P	1.161	0.56
583_G	593_T	1.157	0.56
261_V	275_L	1.155	0.56
94_G	380_T	1.152	0.56
177_Q	180_Q	1.152	0.56
626_C	633_G	1.144	0.55
221_I	254_E	1.142	0.55
223_T	261_V	1.141	0.55
421_L	430_R	1.141	0.55
207_A	489_Y	1.138	0.55
119_D	386_R	1.138	0.55
79_D	379_R	1.135	0.54
397_L	483_Y	1.135	0.54
317_P	545_H	1.134	0.54
355_E	358_L	1.132	0.54
194_V	435_N	1.132	0.54
14_M	98_A	1.131	0.54
616_L	641_Q	1.124	0.54
406_A	472_T	1.123	0.54
458_V	507_C	1.119	0.53
292_E	377_H	1.115	0.53
319_R	377_H	1.115	0.53
306_F	324_C	1.115	0.53
81_R	105_L	1.114	0.53
488_D	588_H	1.113	0.53
123_W	521_S	1.112	0.53
93_S	405_I	1.110	0.53
317_P	327_E	1.109	0.53
208_L	212_L	1.107	0.52
469_R	499_E	1.106	0.52
209_A	283_L	1.105	0.52
438_A	459_S	1.103	0.52
467_R	470_E	1.099	0.52
548_L	552_A	1.095	0.52
292_E	460_R	1.094	0.52
319_R	460_R	1.094	0.52
104_L	286_T	1.093	0.52
532_P	541_A	1.091	0.51
258_W	283_L	1.087	0.51
611_A	641_Q	1.087	0.51
33_F	36_T	1.085	0.51
254_E	279_F	1.082	0.51
27_G	31_W	1.079	0.51
123_W	496_Y	1.077	0.50
78_F	98_A	1.075	0.50
81_R	473_G	1.073	0.50
608_A	611_A	1.072	0.50
273_H	305_R	1.069	0.50
36_T	39_L	1.069	0.50
611_A	640_R	1.068	0.50
93_S	197_V	1.067	0.50
221_I	244_I	1.061	0.49
323_G	328_K	1.060	0.49
187_L	195_A	1.057	0.49
380_T	410_W	1.053	0.49
107_P	297_G	1.048	0.49
68_L	255_Q	1.048	0.49
195_A	258_W	1.038	0.48
328_K	641_Q	1.037	0.48
408_A	526_T	1.037	0.48
573_L	601_L	1.036	0.48
33_F	405_I	1.034	0.48
14_M	17_E	1.033	0.48
94_G	410_W	1.032	0.47
96_L	524_C	1.032	0.47
53_R	63_S	1.032	0.47
22_L	274_Q	1.026	0.47
490_L	494_F	1.023	0.47
226_A	266_A	1.022	0.47
243_F	412_V	1.020	0.47
92_L	95_T	1.020	0.47
422_S	448_P	1.018	0.46
187_L	283_L	1.015	0.46
96_L	229_S	1.014	0.46
86_A	138_H	1.013	0.46
391_A	453_L	1.011	0.46
18_G	98_A	1.010	0.46
200_A	403_N	1.007	0.46
418_S	569_N	1.006	0.46
365_T	400_A	1.003	0.45
417_L	451_A	1.000	0.45
194_V	309_L	0.999	0.45
439_Q	515_G	0.998	0.45
380_T	431_R	0.997	0.45
20_R	24_V	0.992	0.45
213_I	243_F	0.989	0.45
512_V	578_W	0.989	0.45
413_D	454_R	0.988	0.44
290_G	366_P	0.987	0.44
29_E	33_F	0.986	0.44
262_D	327_E	0.985	0.44
580_E	584_F	0.981	0.44
203_R	317_P	0.979	0.44
519_E	524_C	0.977	0.44
500_L	524_C	0.974	0.44
195_A	326_L	0.974	0.44
430_R	469_R	0.973	0.43
444_H	513_R	0.972	0.43
344_T	526_T	0.972	0.43
417_L	529_A	0.971	0.43
350_V	358_L	0.971	0.43
388_M	586_F	0.970	0.43
243_F	249_L	0.966	0.43
293_G	319_R	0.964	0.43
267_I	612_L	0.962	0.43
214_S	556_A	0.960	0.43
17_E	20_R	0.960	0.43
76_A	92_L	0.957	0.42
65_L	391_A	0.955	0.42
419_Q	452_T	0.954	0.42
101_W	307_P	0.953	0.42
513_R	519_E	0.950	0.42
454_R	487_L	0.947	0.42
266_A	513_R	0.946	0.42
40_R	591_L	0.944	0.42
35_H	39_L	0.940	0.41
225_P	444_H	0.940	0.41
245_A	248_A	0.936	0.41
120_S	136_V	0.935	0.41
352_S	483_Y	0.934	0.41
297_G	522_S	0.931	0.41
605_S	608_A	0.927	0.40
580_E	596_G	0.925	0.40
420_Q	478_A	0.925	0.40
445_G	450_A	0.925	0.40
187_L	583_G	0.923	0.40
598_L	641_Q	0.922	0.40
270_P	337_D	0.920	0.40
479_G	482_Q	0.920	0.40
325_P	336_F	0.920	0.40
200_A	289_Q	0.919	0.40
340_N	571_A	0.914	0.40
284_L	389_M	0.913	0.40
324_C	366_P	0.912	0.39
209_A	435_N	0.909	0.39
65_L	88_A	0.908	0.39
282_T	508_G	0.906	0.39
601_L	648_A	0.904	0.39
224_A	288_V	0.903	0.39
18_G	22_L	0.902	0.39
339_E	367_L	0.900	0.39
289_Q	331_S	0.898	0.39
75_H	100_S	0.895	0.38
424_A	537_G	0.895	0.38
221_I	253_D	0.894	0.38
201_R	378_Y	0.891	0.38
201_R	457_R	0.891	0.38
378_Y	457_R	0.891	0.38
194_V	212_L	0.891	0.38
418_S	421_L	0.890	0.38
352_S	400_A	0.887	0.38
393_G	412_V	0.884	0.38
113_E	140_K	0.880	0.37
203_R	262_D	0.879	0.37
219_R	242_R	0.879	0.37
370_Y	379_R	0.877	0.37
22_L	107_P	0.877	0.37
293_G	377_H	0.874	0.37
298_F	302_F	0.873	0.37
130_I	133_P	0.872	0.37
138_H	363_P	0.872	0.37
27_G	32_C	0.871	0.37
424_A	430_R	0.870	0.37
259_L	532_P	0.868	0.37
373_L	521_S	0.868	0.37
407_G	472_T	0.867	0.37
230_T	234_A	0.867	0.37
577_D	600_R	0.863	0.36
138_H	491_S	0.862	0.36
392_P	471_G	0.861	0.36
388_M	442_A	0.861	0.36
35_H	41_D	0.860	0.36
314_L	485_Q	0.860	0.36
425_V	432_P	0.860	0.36
440_S	515_G	0.858	0.36
440_S	443_A	0.857	0.36
320_W	382_P	0.857	0.36
71_R	562_T	0.857	0.36
215_R	286_T	0.856	0.36
224_A	470_E	0.854	0.36
430_R	439_Q	0.853	0.36
293_G	460_R	0.853	0.36
301_K	370_Y	0.852	0.36
200_A	284_L	0.848	0.35
415_G	438_A	0.848	0.35
29_E	139_L	0.844	0.35
384_D	415_G	0.843	0.35
350_V	356_Q	0.842	0.35
459_S	491_S	0.841	0.35
359_W	363_P	0.841	0.35
335_V	458_V	0.837	0.35
399_A	477_I	0.837	0.35
521_S	529_A	0.837	0.35
18_G	21_R	0.837	0.35
84_F	285_T	0.829	0.34
563_L	627_T	0.828	0.34
253_D	278_R	0.827	0.34
353_A	418_S	0.826	0.34
200_A	331_S	0.825	0.34
260_V	309_L	0.825	0.34
484_T	490_L	0.824	0.34
94_G	522_S	0.824	0.34
410_W	577_D	0.824	0.34
37_L	53_R	0.821	0.34
15_K	22_L	0.820	0.34
145_A	159_S	0.820	0.34
125_D	393_G	0.820	0.34
494_F	563_L	0.819	0.34
326_L	484_T	0.817	0.34
420_Q	569_N	0.816	0.34
422_S	425_V	0.810	0.33
528_M	595_L	0.810	0.33
26_S	34_E	0.809	0.33
514_M	538_K	0.809	0.33
88_A	224_A	0.804	0.33
66_Q	440_S	0.804	0.33
46_D	50_I	0.802	0.33
417_L	438_A	0.802	0.33
94_G	102_L	0.802	0.33
23_L	26_S	0.801	0.33
102_L	326_L	0.797	0.32
183_L	186_Q	0.797	0.32
72_E	91_A	0.796	0.32
234_A	388_M	0.796	0.32
135_F	417_L	0.794	0.32
182_Q	562_T	0.792	0.32
273_H	594_S	0.791	0.32
163_F	166_R	0.790	0.32
474_R	576_D	0.790	0.32
428_G	642_R	0.790	0.32
442_A	495_G	0.790	0.32
315_Q	478_A	0.789	0.32
334_L	435_N	0.786	0.32
108_V	112_W	0.786	0.32
154_Q	584_F	0.786	0.32
381_S	566_D	0.786	0.32
217_A	241_F	0.785	0.32
312_F	337_D	0.785	0.32
213_I	284_L	0.784	0.32
14_M	591_L	0.784	0.32
225_P	288_V	0.783	0.32
287_T	327_E	0.782	0.31
30_G	51_S	0.780	0.31
195_A	473_G	0.780	0.31
199_A	490_L	0.779	0.31
299_L	303_C	0.779	0.31
320_W	524_C	0.779	0.31
276_V	518_R	0.778	0.31
121_L	535_D	0.777	0.31
609_L	613_R	0.776	0.31
158_F	162_H	0.775	0.31
109_W	388_M	0.773	0.31
644_E	648_A	0.772	0.31
458_V	533_M	0.772	0.31
201_R	292_E	0.771	0.31
201_R	319_R	0.771	0.31
292_E	378_Y	0.771	0.31
292_E	457_R	0.771	0.31
319_R	378_Y	0.771	0.31
319_R	457_R	0.771	0.31
196_A	224_A	0.770	0.31
420_Q	567_P	0.770	0.31
187_L	190_M	0.768	0.31
73_F	207_A	0.767	0.31
70_G	292_E	0.767	0.31
70_G	319_R	0.767	0.31
320_W	380_T	0.765	0.31
201_R	291_Y	0.763	0.30
291_Y	378_Y	0.763	0.30
291_Y	457_R	0.763	0.30
358_L	365_T	0.761	0.30
376_A	468_Q	0.758	0.30
230_T	497_T	0.757	0.30
594_S	597_C	0.757	0.30
621_S	637_L	0.756	0.30
601_L	652_L	0.755	0.30
527_A	597_C	0.752	0.30
207_A	266_A	0.750	0.30
630_K	650_F	0.749	0.30
300_L	303_C	0.749	0.30
402_E	535_D	0.749	0.30
182_Q	546_Y	0.749	0.30
428_G	432_P	0.749	0.30
350_V	354_F	0.748	0.30
430_R	493_S	0.748	0.30
244_I	253_D	0.747	0.29
363_P	506_R	0.747	0.29
435_N	515_G	0.747	0.29
474_R	478_A	0.747	0.29
352_S	409_L	0.746	0.29
187_L	258_W	0.745	0.29
53_R	562_T	0.745	0.29
335_V	525_Y	0.744	0.29
354_F	398_Q	0.744	0.29
270_P	637_L	0.743	0.29
330_V	333_A	0.742	0.29
138_H	194_V	0.742	0.29
362_D	581_L	0.742	0.29
76_A	187_L	0.740	0.29
431_R	515_G	0.740	0.29
101_W	122_R	0.740	0.29
175_A	276_V	0.740	0.29
337_D	406_A	0.739	0.29
207_A	312_F	0.739	0.29
537_G	540_L	0.739	0.29
125_D	412_V	0.739	0.29
515_G	520_A	0.738	0.29
648_A	652_L	0.737	0.29
217_A	416_G	0.734	0.29
279_F	379_R	0.733	0.29
17_E	21_R	0.733	0.29
535_D	538_K	0.733	0.29
53_R	145_A	0.731	0.29
317_P	430_R	0.730	0.29
134_H	138_H	0.730	0.29
134_H	357_T	0.730	0.29
76_A	225_P	0.729	0.28
73_F	236_F	0.729	0.28
94_G	297_G	0.729	0.28
645_A	649_L	0.729	0.28
386_R	428_G	0.728	0.28
605_S	646_A	0.726	0.28
92_L	96_L	0.726	0.28
532_P	537_G	0.726	0.28
533_M	574_S	0.725	0.28
380_T	394_Q	0.725	0.28
431_R	436_L	0.725	0.28
535_D	539_Q	0.724	0.28
175_A	514_M	0.723	0.28
443_A	456_R	0.723	0.28
274_Q	419_Q	0.722	0.28
191_P	309_L	0.721	0.28
453_L	540_L	0.721	0.28
365_T	405_I	0.721	0.28
176_P	207_A	0.721	0.28
147_N	482_Q	0.721	0.28
190_M	195_A	0.720	0.28
490_L	499_E	0.720	0.28
499_E	506_R	0.719	0.28
56_A	224_A	0.719	0.28
187_L	304_A	0.717	0.28
640_R	646_A	0.717	0.28
633_G	649_L	0.715	0.28
63_S	565_V	0.714	0.28
61_S	64_A	0.712	0.28
249_L	633_G	0.712	0.28
379_R	410_W	0.711	0.28
585_A	646_A	0.711	0.28
201_R	460_R	0.710	0.27
378_Y	460_R	0.710	0.27
457_R	460_R	0.710	0.27
243_F	370_Y	0.710	0.27
351_I	483_Y	0.709	0.27
222_V	243_F	0.708	0.27
272_L	297_G	0.706	0.27
111_E	115_Q	0.705	0.27
241_F	497_T	0.704	0.27
75_H	528_M	0.704	0.27
245_A	317_P	0.704	0.27
193_G	212_L	0.703	0.27
87_A	276_V	0.703	0.27
187_L	286_T	0.703	0.27
307_P	603_Q	0.701	0.27
583_G	589_R	0.700	0.27
188_M	573_L	0.699	0.27
210_G	327_E	0.699	0.27
86_A	329_M	0.698	0.27
201_R	377_H	0.698	0.27
377_H	457_R	0.698	0.27
438_A	442_A	0.695	0.27
15_K	461_I	0.695	0.27
271_L	275_L	0.695	0.27
289_Q	336_F	0.695	0.27
364_E	535_D	0.694	0.27
21_R	27_G	0.694	0.27
105_L	480_A	0.693	0.27
40_R	46_D	0.692	0.26
632_S	636_M	0.691	0.26
262_D	287_T	0.691	0.26
225_P	450_A	0.690	0.26
197_V	285_T	0.689	0.26
294_T	530_L	0.689	0.26
256_A	458_V	0.689	0.26
428_G	431_R	0.688	0.26
300_L	333_A	0.688	0.26
213_I	476_L	0.684	0.26
224_A	432_P	0.684	0.26
249_L	272_L	0.684	0.26
515_G	635_K	0.684	0.26
628_T	649_L	0.684	0.26
349_I	354_F	0.682	0.26
25_L	641_Q	0.681	0.26
155_N	186_Q	0.680	0.26
197_V	474_R	0.679	0.26
631_L	637_L	0.676	0.26
292_E	384_D	0.675	0.26
319_R	384_D	0.675	0.26
19_I	22_L	0.675	0.26
117_D	441_L	0.674	0.26
119_D	122_R	0.674	0.26
379_R	435_N	0.673	0.26
70_G	377_H	0.673	0.26
221_I	241_F	0.673	0.26
139_L	309_L	0.673	0.26
117_D	229_S	0.671	0.25
317_P	344_T	0.671	0.25
532_P	538_K	0.671	0.25
21_R	24_V	0.671	0.25
181_Q	314_L	0.670	0.25
203_R	287_T	0.670	0.25
32_C	36_T	0.669	0.25
256_A	638_L	0.668	0.25
496_Y	529_A	0.668	0.25
161_A	498_G	0.667	0.25
243_F	373_L	0.667	0.25
119_D	125_D	0.667	0.25
349_I	472_T	0.667	0.25
536_A	539_Q	0.666	0.25
464_H	468_Q	0.664	0.25
179_E	330_V	0.662	0.25
195_A	408_A	0.662	0.25
152_W	155_N	0.662	0.25
117_D	432_P	0.661	0.25
394_Q	459_S	0.660	0.25
632_S	639_V	0.660	0.25
272_L	522_S	0.660	0.25
574_S	645_A	0.659	0.25
500_L	548_L	0.658	0.25
371_Q	374_S	0.657	0.25
90_A	518_R	0.657	0.25
387_R	491_S	0.656	0.25
86_A	100_S	0.656	0.25
407_G	534_S	0.655	0.25
287_T	290_G	0.655	0.25
48_L	51_S	0.653	0.25
70_G	460_R	0.651	0.24
94_G	389_M	0.651	0.24
564_P	573_L	0.650	0.24
590_P	593_T	0.650	0.24
168_D	419_Q	0.649	0.24
195_A	312_F	0.649	0.24
82_H	118_A	0.649	0.24
138_H	390_D	0.648	0.24
489_Y	492_V	0.647	0.24
270_P	497_T	0.646	0.24
298_F	376_A	0.646	0.24
438_A	491_S	0.645	0.24
94_G	431_R	0.645	0.24
323_G	458_V	0.645	0.24
438_A	551_D	0.645	0.24
591_L	595_L	0.645	0.24
432_P	441_L	0.643	0.24
93_S	102_L	0.642	0.24
360_Q	389_M	0.642	0.24
509_F	512_V	0.640	0.24
84_F	321_A	0.640	0.24
291_Y	319_R	0.639	0.24
156_Q	578_W	0.639	0.24
26_S	32_C	0.639	0.24
421_L	428_G	0.638	0.24
269_A	294_T	0.638	0.24
98_A	119_D	0.637	0.24
179_E	556_A	0.637	0.24
370_Y	394_Q	0.637	0.24
267_I	453_L	0.636	0.24
214_S	312_F	0.635	0.24
158_F	449_L	0.634	0.24
326_L	600_R	0.634	0.24
567_P	601_L	0.634	0.24
427_A	451_A	0.634	0.24
416_G	442_A	0.634	0.24
451_A	488_D	0.633	0.24
353_A	358_L	0.632	0.23
107_P	440_S	0.632	0.23
276_V	282_T	0.632	0.23
169_W	267_I	0.631	0.23
509_F	583_G	0.631	0.23
209_A	213_I	0.630	0.23
446_N	515_G	0.628	0.23
304_A	381_S	0.628	0.23
286_T	627_T	0.628	0.23
89_F	282_T	0.627	0.23
370_Y	410_W	0.627	0.23
426_W	524_C	0.627	0.23
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307_P	311_R	0.626	0.23
501_W	509_F	0.626	0.23
86_A	109_W	0.626	0.23
458_V	508_G	0.626	0.23
168_D	328_K	0.626	0.23
377_H	434_G	0.626	0.23
249_L	494_F	0.624	0.23
95_T	432_P	0.623	0.23
438_A	455_G	0.623	0.23
348_N	358_L	0.622	0.23
421_L	512_V	0.622	0.23
330_V	465_P	0.621	0.23
179_E	208_L	0.621	0.23
301_K	412_V	0.621	0.23
410_W	459_S	0.621	0.23
81_R	86_A	0.619	0.23
374_S	560_G	0.618	0.23
375_G	400_A	0.618	0.23
591_L	616_L	0.618	0.23
401_G	405_I	0.618	0.23
33_F	41_D	0.617	0.23
25_L	49_W	0.616	0.23
139_L	143_L	0.615	0.23
228_A	311_R	0.614	0.23
66_Q	484_T	0.613	0.23
492_V	522_S	0.612	0.23
644_E	649_L	0.612	0.23
411_L	509_F	0.612	0.23
221_I	278_R	0.611	0.22
274_Q	424_A	0.611	0.22
396_F	408_A	0.611	0.22
217_A	585_A	0.610	0.22
299_L	359_W	0.610	0.22
394_Q	455_G	0.610	0.22
124_S	392_P	0.609	0.22
25_L	127_P	0.608	0.22
234_A	276_V	0.608	0.22
92_L	513_R	0.607	0.22
26_S	391_A	0.607	0.22
387_R	391_A	0.607	0.22
158_F	574_S	0.606	0.22
409_L	532_P	0.606	0.22
306_F	592_L	0.606	0.22
388_M	396_F	0.605	0.22
243_F	443_A	0.604	0.22
160_L	538_K	0.604	0.22
251_A	539_Q	0.604	0.22
310_H	317_P	0.603	0.22
325_P	478_A	0.602	0.22
621_S	624_Q	0.601	0.22
25_L	546_Y	0.601	0.22
345_P	362_D	0.600	0.22
105_L	500_L	0.600	0.22
294_T	560_G	0.600	0.22
287_T	317_P	0.599	0.22
338_D	556_A	0.599	0.22
14_M	101_W	0.599	0.22
26_S	256_A	0.598	0.22
434_G	460_R	0.598	0.22
460_R	523_G	0.598	0.22
549_R	605_S	0.598	0.22
423_Q	486_D	0.596	0.22
419_Q	538_K	0.596	0.22
224_A	494_F	0.596	0.22
401_G	406_A	0.595	0.22
442_A	451_A	0.595	0.22
73_F	312_F	0.595	0.22
221_I	279_F	0.594	0.22
266_A	451_A	0.593	0.22
439_Q	445_G	0.593	0.22
444_H	484_T	0.591	0.22
430_R	642_R	0.590	0.21
328_K	332_E	0.589	0.21
197_V	368_K	0.589	0.21
421_L	649_L	0.589	0.21
422_S	513_R	0.589	0.21
185_K	341_F	0.588	0.21
230_T	333_A	0.588	0.21
388_M	547_R	0.588	0.21
526_T	574_S	0.587	0.21
245_A	493_S	0.586	0.21
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507_C	585_A	0.585	0.21
377_H	384_D	0.585	0.21
318_I	464_H	0.585	0.21
162_H	542_E	0.583	0.21
289_Q	374_S	0.583	0.21
436_L	515_G	0.582	0.21
499_E	542_E	0.582	0.21
334_L	351_I	0.581	0.21
257_D	337_D	0.581	0.21
34_E	367_L	0.580	0.21
455_G	468_Q	0.579	0.21
387_R	399_A	0.579	0.21
301_K	432_P	0.579	0.21
566_D	610_P	0.579	0.21
455_G	464_H	0.578	0.21
76_A	267_I	0.577	0.21
382_P	523_G	0.576	0.21
291_Y	460_R	0.576	0.21
318_I	454_R	0.575	0.21
288_V	598_L	0.574	0.21
247_D	430_R	0.574	0.21
611_A	617_Q	0.573	0.21
559_N	648_A	0.572	0.21
329_M	465_P	0.571	0.21
374_S	485_Q	0.570	0.21
377_H	523_G	0.570	0.21
175_A	317_P	0.570	0.21
487_L	534_S	0.569	0.21
150_I	470_E	0.569	0.21
142_V	365_T	0.568	0.21
48_L	248_A	0.568	0.21
117_D	122_R	0.567	0.20
580_E	589_R	0.567	0.20
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37_L	41_D	0.566	0.20
129_P	213_I	0.566	0.20
394_Q	521_S	0.566	0.20
79_D	386_R	0.566	0.20
199_A	421_L	0.564	0.20
259_L	381_S	0.564	0.20
164_T	362_D	0.563	0.20
311_R	458_V	0.562	0.20
71_R	226_A	0.562	0.20
267_I	446_N	0.562	0.20
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384_D	460_R	0.561	0.20
416_G	449_L	0.561	0.20
302_F	522_S	0.561	0.20
514_M	594_S	0.560	0.20
42_A	630_K	0.559	0.20
391_A	520_A	0.559	0.20
247_D	317_P	0.558	0.20
155_N	245_A	0.558	0.20
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445_G	476_L	0.558	0.20
280_P	519_E	0.557	0.20
296_R	524_C	0.556	0.20
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502_R	596_G	0.556	0.20
22_L	27_G	0.555	0.20
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430_R	526_T	0.552	0.20
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431_R	494_F	0.551	0.20
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479_G	594_S	0.550	0.20
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535_D	569_N	0.546	0.20
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495_G	523_G	0.545	0.20
216_I	221_I	0.544	0.19
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312_F	624_Q	0.534	0.19
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320_W	455_G	0.533	0.19
28_E	474_R	0.533	0.19
120_S	125_D	0.532	0.19
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276_V	618_K	0.532	0.19
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448_P	510_V	0.528	0.19
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293_G	457_R	0.526	0.19
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220_A	267_I	0.517	0.18
512_V	537_G	0.516	0.18
337_D	465_P	0.516	0.18
202_G	263_E	0.515	0.18
204_G	263_E	0.515	0.18
205_K	263_E	0.515	0.18
157_P	222_V	0.514	0.18
315_Q	322_Q	0.514	0.18
20_R	25_L	0.513	0.18
329_M	383_L	0.512	0.18
325_P	430_R	0.512	0.18
315_Q	591_L	0.511	0.18
509_F	614_G	0.509	0.18
482_Q	549_R	0.508	0.18
405_I	643_E	0.508	0.18
220_A	637_L	0.508	0.18
288_V	465_P	0.508	0.18
391_A	495_G	0.508	0.18
94_G	372_L	0.507	0.18
50_I	54_P	0.507	0.18
70_G	293_G	0.507	0.18
41_D	156_Q	0.505	0.18
258_W	396_F	0.505	0.18
73_F	95_T	0.505	0.18
272_L	435_N	0.505	0.18
72_E	320_W	0.504	0.18
176_P	517_H	0.504	0.18
338_D	374_S	0.504	0.18
515_G	599_L	0.504	0.18
270_P	523_G	0.504	0.18
398_Q	405_I	0.504	0.18
342_T	578_W	0.503	0.18
134_H	356_Q	0.502	0.18
352_S	499_E	0.502	0.18
394_Q	596_G	0.501	0.18
103_V	477_I	0.501	0.18
360_Q	398_Q	0.501	0.18
344_T	581_L	0.500	0.18
28_E	53_R	0.500	0.18
313_E	548_L	0.500	0.18
158_F	538_K	0.500	0.18

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2zpaA	1	0.9866	100	0.341	Contact Map
2reeA	1	0.2429	99.5	0.929	Contact Map
3c26A	2	0.3383	99.4	0.934	Contact Map
1z4rA	1	0.228	99.2	0.938	Contact Map
1n71A	4	0.2206	99.2	0.939	Contact Map
1kzfA	1	0.2653	99.2	0.94	Contact Map
3efaA	2	0.2116	99.2	0.94	Contact Map
4r3lA	1	0.228	99.1	0.941	Contact Map
2q0yA	2	0.2131	99.1	0.941	Contact Map
1yghA	1	0.2355	99.1	0.942	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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