GREMLIN Database
TMCA - tRNA(Met) cytidine acetyltransferase TmcA
UniProt: P76562 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14196
Length: 671 (635)
Sequences: 786 (546)
Seq/√Len: 21.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
492_V529_A7.8181.00
184_L208_L7.6511.00
407_G463_V6.4701.00
399_A472_T6.3461.00
481_L531_L5.9831.00
84_F89_F5.9591.00
437_V491_S5.6211.00
477_I507_C5.3021.00
458_V477_I5.0171.00
474_R507_C4.9781.00
477_I509_F4.5411.00
614_G625_L4.3711.00
222_V233_L4.1331.00
413_D456_R3.9391.00
207_A236_F3.8131.00
230_T233_L3.7721.00
495_G500_L3.7661.00
74_R97_K3.6601.00
512_V530_L3.6161.00
455_G489_Y3.5051.00
261_V284_L3.4511.00
213_I260_V3.3541.00
465_P468_Q3.1651.00
511_L527_A3.0641.00
225_P266_A2.9940.99
437_V528_M2.9310.99
237_A241_F2.8920.99
495_G524_C2.8410.99
369_V405_I2.7790.99
296_R495_G2.7630.99
447_N544_E2.7110.99
369_V396_F2.7070.99
369_V408_A2.6730.99
373_L408_A2.6430.99
209_A285_T2.6300.99
224_A243_F2.6210.99
284_L302_F2.6120.98
354_F359_W2.6010.98
354_F358_L2.5860.98
441_L512_V2.5680.98
259_L279_F2.5450.98
338_D371_Q2.5420.98
259_L275_L2.4890.98
620_A628_T2.4230.97
547_R580_E2.4100.97
369_V388_M2.3780.97
117_D386_R2.3670.97
436_L493_S2.3540.97
26_S405_I2.3500.97
455_G491_S2.2270.96
440_S513_R2.2170.96
399_A407_G2.2090.96
394_Q410_W2.1960.95
409_L476_L2.1900.95
175_A184_L2.1600.95
368_K404_E2.1510.95
89_F330_V2.1430.95
538_K567_P2.0170.93
296_R500_L2.0010.93
456_R487_L1.9890.92
407_G476_L1.9770.92
468_Q473_G1.9650.92
633_G642_R1.9560.92
488_D534_S1.9350.91
184_L211_Q1.9310.91
550_R577_D1.9260.91
510_V545_H1.9150.91
409_L480_A1.8830.90
337_D367_L1.8790.90
65_L91_A1.8750.90
31_W154_Q1.8640.89
225_P267_I1.8620.89
614_G620_A1.8510.89
286_T298_F1.8390.89
84_F391_A1.8210.88
359_W389_M1.8060.88
591_L615_R1.8060.88
379_R519_E1.7890.87
213_I233_L1.7880.87
296_R302_F1.7780.87
87_A383_L1.7740.87
90_A334_L1.7680.87
207_A232_V1.7450.86
84_F368_K1.7290.86
179_E315_Q1.7240.85
272_L302_F1.7190.85
372_L436_L1.7160.85
611_A629_L1.7050.85
379_R521_S1.7050.85
591_L622_D1.6810.84
316_Q322_Q1.6800.84
440_S528_M1.6750.84
28_E154_Q1.6700.83
525_Y560_G1.6670.83
222_V234_A1.6630.83
15_K18_G1.6600.83
72_E98_A1.6530.83
196_A303_C1.6480.83
456_R484_T1.6450.83
259_L282_T1.6410.82
377_H460_R1.6260.82
203_R327_E1.6160.81
355_E359_W1.6100.81
494_F583_G1.6090.81
424_A429_F1.6030.81
374_S511_L1.6010.81
24_V27_G1.5970.81
615_R622_D1.5860.80
430_R515_G1.5510.79
187_L197_V1.5480.78
183_L197_V1.5330.78
412_V459_S1.5220.77
190_M193_G1.5170.77
197_V312_F1.4840.75
93_S330_V1.4800.75
386_R432_P1.4710.75
103_V312_F1.4700.75
135_F391_A1.4570.74
107_P112_W1.4540.74
440_S444_H1.4510.74
260_V388_M1.4480.73
496_Y501_W1.4430.73
20_R27_G1.4420.73
407_G603_Q1.4380.73
197_V396_F1.4290.72
23_L103_V1.4290.72
26_S35_H1.4230.72
416_G438_A1.4200.72
212_L258_W1.4190.72
625_L637_L1.4190.72
514_M593_T1.4160.72
106_L112_W1.4160.72
209_A220_A1.4090.71
539_Q604_T1.4030.71
230_T285_T1.3990.71
186_Q310_H1.3910.70
269_A302_F1.3890.70
222_V464_H1.3860.70
614_G628_T1.3810.70
336_F501_W1.3810.70
109_W140_K1.3730.69
444_H517_H1.3720.69
474_R477_I1.3530.68
14_M19_I1.3370.67
359_W362_D1.3360.67
372_L468_Q1.3330.67
74_R100_S1.3330.67
25_L103_V1.3240.66
136_V198_T1.3220.66
437_V455_G1.3210.66
556_A620_A1.3140.66
64_A229_S1.3090.66
411_L456_R1.3060.65
60_C219_R1.3020.65
614_G629_L1.3000.65
14_M18_G1.2990.65
403_N546_Y1.2970.65
253_D279_F1.2910.64
85_D383_L1.2910.64
16_R19_I1.2880.64
534_S537_G1.2870.64
356_Q359_W1.2860.64
297_G302_F1.2810.64
329_M333_A1.2720.63
84_F425_V1.2670.63
286_T649_L1.2590.62
269_A526_T1.2550.62
197_V514_M1.2420.61
336_F548_L1.2350.61
275_L279_F1.2340.61
552_A560_G1.2330.61
76_A284_L1.2310.61
574_S624_Q1.2300.61
321_A325_P1.2170.60
352_S395_H1.2160.60
502_R506_R1.2140.60
474_R506_R1.2130.60
72_E247_D1.2120.59
395_H413_D1.2090.59
292_E319_R1.2020.59
177_Q388_M1.1920.58
318_I374_S1.1880.58
35_H530_L1.1880.58
476_L480_A1.1870.58
612_L637_L1.1870.58
17_E22_L1.1850.58
254_E259_L1.1770.57
96_L102_L1.1770.57
223_T226_A1.1750.57
379_R455_G1.1710.57
15_K19_I1.1700.57
481_L509_F1.1650.56
573_L577_D1.1620.56
138_H142_V1.1620.56
197_V564_P1.1610.56
583_G593_T1.1570.56
261_V275_L1.1550.56
94_G380_T1.1520.56
177_Q180_Q1.1520.56
626_C633_G1.1440.55
221_I254_E1.1420.55
223_T261_V1.1410.55
421_L430_R1.1410.55
207_A489_Y1.1380.55
119_D386_R1.1380.55
79_D379_R1.1350.54
397_L483_Y1.1350.54
317_P545_H1.1340.54
355_E358_L1.1320.54
194_V435_N1.1320.54
14_M98_A1.1310.54
616_L641_Q1.1240.54
406_A472_T1.1230.54
458_V507_C1.1190.53
292_E377_H1.1150.53
319_R377_H1.1150.53
306_F324_C1.1150.53
81_R105_L1.1140.53
488_D588_H1.1130.53
123_W521_S1.1120.53
93_S405_I1.1100.53
317_P327_E1.1090.53
208_L212_L1.1070.52
469_R499_E1.1060.52
209_A283_L1.1050.52
438_A459_S1.1030.52
467_R470_E1.0990.52
548_L552_A1.0950.52
292_E460_R1.0940.52
319_R460_R1.0940.52
104_L286_T1.0930.52
532_P541_A1.0910.51
258_W283_L1.0870.51
611_A641_Q1.0870.51
33_F36_T1.0850.51
254_E279_F1.0820.51
27_G31_W1.0790.51
123_W496_Y1.0770.50
78_F98_A1.0750.50
81_R473_G1.0730.50
608_A611_A1.0720.50
273_H305_R1.0690.50
36_T39_L1.0690.50
611_A640_R1.0680.50
93_S197_V1.0670.50
221_I244_I1.0610.49
323_G328_K1.0600.49
187_L195_A1.0570.49
380_T410_W1.0530.49
107_P297_G1.0480.49
68_L255_Q1.0480.49
195_A258_W1.0380.48
328_K641_Q1.0370.48
408_A526_T1.0370.48
573_L601_L1.0360.48
33_F405_I1.0340.48
14_M17_E1.0330.48
94_G410_W1.0320.47
96_L524_C1.0320.47
53_R63_S1.0320.47
22_L274_Q1.0260.47
490_L494_F1.0230.47
226_A266_A1.0220.47
243_F412_V1.0200.47
92_L95_T1.0200.47
422_S448_P1.0180.46
187_L283_L1.0150.46
96_L229_S1.0140.46
86_A138_H1.0130.46
391_A453_L1.0110.46
18_G98_A1.0100.46
200_A403_N1.0070.46
418_S569_N1.0060.46
365_T400_A1.0030.45
417_L451_A1.0000.45
194_V309_L0.9990.45
439_Q515_G0.9980.45
380_T431_R0.9970.45
20_R24_V0.9920.45
213_I243_F0.9890.45
512_V578_W0.9890.45
413_D454_R0.9880.44
290_G366_P0.9870.44
29_E33_F0.9860.44
262_D327_E0.9850.44
580_E584_F0.9810.44
203_R317_P0.9790.44
519_E524_C0.9770.44
500_L524_C0.9740.44
195_A326_L0.9740.44
430_R469_R0.9730.43
444_H513_R0.9720.43
344_T526_T0.9720.43
417_L529_A0.9710.43
350_V358_L0.9710.43
388_M586_F0.9700.43
243_F249_L0.9660.43
293_G319_R0.9640.43
267_I612_L0.9620.43
214_S556_A0.9600.43
17_E20_R0.9600.43
76_A92_L0.9570.42
65_L391_A0.9550.42
419_Q452_T0.9540.42
101_W307_P0.9530.42
513_R519_E0.9500.42
454_R487_L0.9470.42
266_A513_R0.9460.42
40_R591_L0.9440.42
35_H39_L0.9400.41
225_P444_H0.9400.41
245_A248_A0.9360.41
120_S136_V0.9350.41
352_S483_Y0.9340.41
297_G522_S0.9310.41
605_S608_A0.9270.40
580_E596_G0.9250.40
420_Q478_A0.9250.40
445_G450_A0.9250.40
187_L583_G0.9230.40
598_L641_Q0.9220.40
270_P337_D0.9200.40
479_G482_Q0.9200.40
325_P336_F0.9200.40
200_A289_Q0.9190.40
340_N571_A0.9140.40
284_L389_M0.9130.40
324_C366_P0.9120.39
209_A435_N0.9090.39
65_L88_A0.9080.39
282_T508_G0.9060.39
601_L648_A0.9040.39
224_A288_V0.9030.39
18_G22_L0.9020.39
339_E367_L0.9000.39
289_Q331_S0.8980.39
75_H100_S0.8950.38
424_A537_G0.8950.38
221_I253_D0.8940.38
201_R378_Y0.8910.38
201_R457_R0.8910.38
378_Y457_R0.8910.38
194_V212_L0.8910.38
418_S421_L0.8900.38
352_S400_A0.8870.38
393_G412_V0.8840.38
113_E140_K0.8800.37
203_R262_D0.8790.37
219_R242_R0.8790.37
370_Y379_R0.8770.37
22_L107_P0.8770.37
293_G377_H0.8740.37
298_F302_F0.8730.37
130_I133_P0.8720.37
138_H363_P0.8720.37
27_G32_C0.8710.37
424_A430_R0.8700.37
259_L532_P0.8680.37
373_L521_S0.8680.37
407_G472_T0.8670.37
230_T234_A0.8670.37
577_D600_R0.8630.36
138_H491_S0.8620.36
392_P471_G0.8610.36
388_M442_A0.8610.36
35_H41_D0.8600.36
314_L485_Q0.8600.36
425_V432_P0.8600.36
440_S515_G0.8580.36
440_S443_A0.8570.36
320_W382_P0.8570.36
71_R562_T0.8570.36
215_R286_T0.8560.36
224_A470_E0.8540.36
430_R439_Q0.8530.36
293_G460_R0.8530.36
301_K370_Y0.8520.36
200_A284_L0.8480.35
415_G438_A0.8480.35
29_E139_L0.8440.35
384_D415_G0.8430.35
350_V356_Q0.8420.35
459_S491_S0.8410.35
359_W363_P0.8410.35
335_V458_V0.8370.35
399_A477_I0.8370.35
521_S529_A0.8370.35
18_G21_R0.8370.35
84_F285_T0.8290.34
563_L627_T0.8280.34
253_D278_R0.8270.34
353_A418_S0.8260.34
200_A331_S0.8250.34
260_V309_L0.8250.34
484_T490_L0.8240.34
94_G522_S0.8240.34
410_W577_D0.8240.34
37_L53_R0.8210.34
15_K22_L0.8200.34
145_A159_S0.8200.34
125_D393_G0.8200.34
494_F563_L0.8190.34
326_L484_T0.8170.34
420_Q569_N0.8160.34
422_S425_V0.8100.33
528_M595_L0.8100.33
26_S34_E0.8090.33
514_M538_K0.8090.33
88_A224_A0.8040.33
66_Q440_S0.8040.33
46_D50_I0.8020.33
417_L438_A0.8020.33
94_G102_L0.8020.33
23_L26_S0.8010.33
102_L326_L0.7970.32
183_L186_Q0.7970.32
72_E91_A0.7960.32
234_A388_M0.7960.32
135_F417_L0.7940.32
182_Q562_T0.7920.32
273_H594_S0.7910.32
163_F166_R0.7900.32
474_R576_D0.7900.32
428_G642_R0.7900.32
442_A495_G0.7900.32
315_Q478_A0.7890.32
334_L435_N0.7860.32
108_V112_W0.7860.32
154_Q584_F0.7860.32
381_S566_D0.7860.32
217_A241_F0.7850.32
312_F337_D0.7850.32
213_I284_L0.7840.32
14_M591_L0.7840.32
225_P288_V0.7830.32
287_T327_E0.7820.31
30_G51_S0.7800.31
195_A473_G0.7800.31
199_A490_L0.7790.31
299_L303_C0.7790.31
320_W524_C0.7790.31
276_V518_R0.7780.31
121_L535_D0.7770.31
609_L613_R0.7760.31
158_F162_H0.7750.31
109_W388_M0.7730.31
644_E648_A0.7720.31
458_V533_M0.7720.31
201_R292_E0.7710.31
201_R319_R0.7710.31
292_E378_Y0.7710.31
292_E457_R0.7710.31
319_R378_Y0.7710.31
319_R457_R0.7710.31
196_A224_A0.7700.31
420_Q567_P0.7700.31
187_L190_M0.7680.31
73_F207_A0.7670.31
70_G292_E0.7670.31
70_G319_R0.7670.31
320_W380_T0.7650.31
201_R291_Y0.7630.30
291_Y378_Y0.7630.30
291_Y457_R0.7630.30
358_L365_T0.7610.30
376_A468_Q0.7580.30
230_T497_T0.7570.30
594_S597_C0.7570.30
621_S637_L0.7560.30
601_L652_L0.7550.30
527_A597_C0.7520.30
207_A266_A0.7500.30
630_K650_F0.7490.30
300_L303_C0.7490.30
402_E535_D0.7490.30
182_Q546_Y0.7490.30
428_G432_P0.7490.30
350_V354_F0.7480.30
430_R493_S0.7480.30
244_I253_D0.7470.29
363_P506_R0.7470.29
435_N515_G0.7470.29
474_R478_A0.7470.29
352_S409_L0.7460.29
187_L258_W0.7450.29
53_R562_T0.7450.29
335_V525_Y0.7440.29
354_F398_Q0.7440.29
270_P637_L0.7430.29
330_V333_A0.7420.29
138_H194_V0.7420.29
362_D581_L0.7420.29
76_A187_L0.7400.29
431_R515_G0.7400.29
101_W122_R0.7400.29
175_A276_V0.7400.29
337_D406_A0.7390.29
207_A312_F0.7390.29
537_G540_L0.7390.29
125_D412_V0.7390.29
515_G520_A0.7380.29
648_A652_L0.7370.29
217_A416_G0.7340.29
279_F379_R0.7330.29
17_E21_R0.7330.29
535_D538_K0.7330.29
53_R145_A0.7310.29
317_P430_R0.7300.29
134_H138_H0.7300.29
134_H357_T0.7300.29
76_A225_P0.7290.28
73_F236_F0.7290.28
94_G297_G0.7290.28
645_A649_L0.7290.28
386_R428_G0.7280.28
605_S646_A0.7260.28
92_L96_L0.7260.28
532_P537_G0.7260.28
533_M574_S0.7250.28
380_T394_Q0.7250.28
431_R436_L0.7250.28
535_D539_Q0.7240.28
175_A514_M0.7230.28
443_A456_R0.7230.28
274_Q419_Q0.7220.28
191_P309_L0.7210.28
453_L540_L0.7210.28
365_T405_I0.7210.28
176_P207_A0.7210.28
147_N482_Q0.7210.28
190_M195_A0.7200.28
490_L499_E0.7200.28
499_E506_R0.7190.28
56_A224_A0.7190.28
187_L304_A0.7170.28
640_R646_A0.7170.28
633_G649_L0.7150.28
63_S565_V0.7140.28
61_S64_A0.7120.28
249_L633_G0.7120.28
379_R410_W0.7110.28
585_A646_A0.7110.28
201_R460_R0.7100.27
378_Y460_R0.7100.27
457_R460_R0.7100.27
243_F370_Y0.7100.27
351_I483_Y0.7090.27
222_V243_F0.7080.27
272_L297_G0.7060.27
111_E115_Q0.7050.27
241_F497_T0.7040.27
75_H528_M0.7040.27
245_A317_P0.7040.27
193_G212_L0.7030.27
87_A276_V0.7030.27
187_L286_T0.7030.27
307_P603_Q0.7010.27
583_G589_R0.7000.27
188_M573_L0.6990.27
210_G327_E0.6990.27
86_A329_M0.6980.27
201_R377_H0.6980.27
377_H457_R0.6980.27
438_A442_A0.6950.27
15_K461_I0.6950.27
271_L275_L0.6950.27
289_Q336_F0.6950.27
364_E535_D0.6940.27
21_R27_G0.6940.27
105_L480_A0.6930.27
40_R46_D0.6920.26
632_S636_M0.6910.26
262_D287_T0.6910.26
225_P450_A0.6900.26
197_V285_T0.6890.26
294_T530_L0.6890.26
256_A458_V0.6890.26
428_G431_R0.6880.26
300_L333_A0.6880.26
213_I476_L0.6840.26
224_A432_P0.6840.26
249_L272_L0.6840.26
515_G635_K0.6840.26
628_T649_L0.6840.26
349_I354_F0.6820.26
25_L641_Q0.6810.26
155_N186_Q0.6800.26
197_V474_R0.6790.26
631_L637_L0.6760.26
292_E384_D0.6750.26
319_R384_D0.6750.26
19_I22_L0.6750.26
117_D441_L0.6740.26
119_D122_R0.6740.26
379_R435_N0.6730.26
70_G377_H0.6730.26
221_I241_F0.6730.26
139_L309_L0.6730.26
117_D229_S0.6710.25
317_P344_T0.6710.25
532_P538_K0.6710.25
21_R24_V0.6710.25
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119_D125_D0.6670.25
349_I472_T0.6670.25
536_A539_Q0.6660.25
464_H468_Q0.6640.25
179_E330_V0.6620.25
195_A408_A0.6620.25
152_W155_N0.6620.25
117_D432_P0.6610.25
394_Q459_S0.6600.25
632_S639_V0.6600.25
272_L522_S0.6600.25
574_S645_A0.6590.25
500_L548_L0.6580.25
371_Q374_S0.6570.25
90_A518_R0.6570.25
387_R491_S0.6560.25
86_A100_S0.6560.25
407_G534_S0.6550.25
287_T290_G0.6550.25
48_L51_S0.6530.25
70_G460_R0.6510.24
94_G389_M0.6510.24
564_P573_L0.6500.24
590_P593_T0.6500.24
168_D419_Q0.6490.24
195_A312_F0.6490.24
82_H118_A0.6490.24
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489_Y492_V0.6470.24
270_P497_T0.6460.24
298_F376_A0.6460.24
438_A491_S0.6450.24
94_G431_R0.6450.24
323_G458_V0.6450.24
438_A551_D0.6450.24
591_L595_L0.6450.24
432_P441_L0.6430.24
93_S102_L0.6420.24
360_Q389_M0.6420.24
509_F512_V0.6400.24
84_F321_A0.6400.24
291_Y319_R0.6390.24
156_Q578_W0.6390.24
26_S32_C0.6390.24
421_L428_G0.6380.24
269_A294_T0.6380.24
98_A119_D0.6370.24
179_E556_A0.6370.24
370_Y394_Q0.6370.24
267_I453_L0.6360.24
214_S312_F0.6350.24
158_F449_L0.6340.24
326_L600_R0.6340.24
567_P601_L0.6340.24
427_A451_A0.6340.24
416_G442_A0.6340.24
451_A488_D0.6330.24
353_A358_L0.6320.23
107_P440_S0.6320.23
276_V282_T0.6320.23
169_W267_I0.6310.23
509_F583_G0.6310.23
209_A213_I0.6300.23
446_N515_G0.6280.23
304_A381_S0.6280.23
286_T627_T0.6280.23
89_F282_T0.6270.23
370_Y410_W0.6270.23
426_W524_C0.6270.23
90_A336_F0.6270.23
307_P311_R0.6260.23
501_W509_F0.6260.23
86_A109_W0.6260.23
458_V508_G0.6260.23
168_D328_K0.6260.23
377_H434_G0.6260.23
249_L494_F0.6240.23
95_T432_P0.6230.23
438_A455_G0.6230.23
348_N358_L0.6220.23
421_L512_V0.6220.23
330_V465_P0.6210.23
179_E208_L0.6210.23
301_K412_V0.6210.23
410_W459_S0.6210.23
81_R86_A0.6190.23
374_S560_G0.6180.23
375_G400_A0.6180.23
591_L616_L0.6180.23
401_G405_I0.6180.23
33_F41_D0.6170.23
25_L49_W0.6160.23
139_L143_L0.6150.23
228_A311_R0.6140.23
66_Q484_T0.6130.23
492_V522_S0.6120.23
644_E649_L0.6120.23
411_L509_F0.6120.23
221_I278_R0.6110.22
274_Q424_A0.6110.22
396_F408_A0.6110.22
217_A585_A0.6100.22
299_L359_W0.6100.22
394_Q455_G0.6100.22
124_S392_P0.6090.22
25_L127_P0.6080.22
234_A276_V0.6080.22
92_L513_R0.6070.22
26_S391_A0.6070.22
387_R391_A0.6070.22
158_F574_S0.6060.22
409_L532_P0.6060.22
306_F592_L0.6060.22
388_M396_F0.6050.22
243_F443_A0.6040.22
160_L538_K0.6040.22
251_A539_Q0.6040.22
310_H317_P0.6030.22
325_P478_A0.6020.22
621_S624_Q0.6010.22
25_L546_Y0.6010.22
345_P362_D0.6000.22
105_L500_L0.6000.22
294_T560_G0.6000.22
287_T317_P0.5990.22
338_D556_A0.5990.22
14_M101_W0.5990.22
26_S256_A0.5980.22
434_G460_R0.5980.22
460_R523_G0.5980.22
549_R605_S0.5980.22
423_Q486_D0.5960.22
419_Q538_K0.5960.22
224_A494_F0.5960.22
401_G406_A0.5950.22
442_A451_A0.5950.22
73_F312_F0.5950.22
221_I279_F0.5940.22
266_A451_A0.5930.22
439_Q445_G0.5930.22
444_H484_T0.5910.22
430_R642_R0.5900.21
328_K332_E0.5890.21
197_V368_K0.5890.21
421_L649_L0.5890.21
422_S513_R0.5890.21
185_K341_F0.5880.21
230_T333_A0.5880.21
388_M547_R0.5880.21
526_T574_S0.5870.21
245_A493_S0.5860.21
203_R210_G0.5850.21
507_C585_A0.5850.21
377_H384_D0.5850.21
318_I464_H0.5850.21
162_H542_E0.5830.21
289_Q374_S0.5830.21
436_L515_G0.5820.21
499_E542_E0.5820.21
334_L351_I0.5810.21
257_D337_D0.5810.21
34_E367_L0.5800.21
455_G468_Q0.5790.21
387_R399_A0.5790.21
301_K432_P0.5790.21
566_D610_P0.5790.21
455_G464_H0.5780.21
76_A267_I0.5770.21
382_P523_G0.5760.21
291_Y460_R0.5760.21
318_I454_R0.5750.21
288_V598_L0.5740.21
247_D430_R0.5740.21
611_A617_Q0.5730.21
559_N648_A0.5720.21
329_M465_P0.5710.21
374_S485_Q0.5700.21
377_H523_G0.5700.21
175_A317_P0.5700.21
487_L534_S0.5690.21
150_I470_E0.5690.21
142_V365_T0.5680.21
48_L248_A0.5680.21
117_D122_R0.5670.20
580_E589_R0.5670.20
91_A435_N0.5660.20
37_L41_D0.5660.20
129_P213_I0.5660.20
394_Q521_S0.5660.20
79_D386_R0.5660.20
199_A421_L0.5640.20
259_L381_S0.5640.20
164_T362_D0.5630.20
311_R458_V0.5620.20
71_R226_A0.5620.20
267_I446_N0.5620.20
291_Y377_H0.5610.20
384_D460_R0.5610.20
416_G449_L0.5610.20
302_F522_S0.5610.20
514_M594_S0.5600.20
42_A630_K0.5590.20
391_A520_A0.5590.20
247_D317_P0.5580.20
155_N245_A0.5580.20
184_L575_D0.5580.20
445_G476_L0.5580.20
280_P519_E0.5570.20
296_R524_C0.5560.20
14_M84_F0.5560.20
502_R596_G0.5560.20
22_L27_G0.5550.20
105_L473_G0.5540.20
259_L436_L0.5540.20
209_A318_I0.5540.20
41_D108_V0.5530.20
336_F459_S0.5530.20
430_R526_T0.5520.20
210_G434_G0.5520.20
431_R494_F0.5510.20
209_A387_R0.5500.20
15_K333_A0.5500.20
479_G594_S0.5500.20
90_A493_S0.5490.20
171_P458_V0.5470.20
234_A383_L0.5470.20
338_D363_P0.5470.20
84_F392_P0.5470.20
480_A483_Y0.5460.20
51_S465_P0.5460.20
535_D569_N0.5460.20
260_V300_L0.5450.20
495_G523_G0.5450.20
216_I221_I0.5440.19
285_T488_D0.5440.19
423_Q448_P0.5430.19
15_K20_R0.5410.19
245_A249_L0.5400.19
87_A296_R0.5390.19
127_P215_R0.5390.19
178_P347_G0.5390.19
330_V580_E0.5380.19
458_V509_F0.5370.19
351_I604_T0.5360.19
167_T235_Q0.5360.19
325_P532_P0.5350.19
79_D428_G0.5350.19
145_A361_S0.5340.19
259_L370_Y0.5340.19
78_F143_L0.5340.19
312_F624_Q0.5340.19
175_A316_Q0.5330.19
260_V429_F0.5330.19
444_H520_A0.5330.19
320_W455_G0.5330.19
28_E474_R0.5330.19
120_S125_D0.5320.19
62_P98_A0.5320.19
276_V618_K0.5320.19
329_M580_E0.5310.19
229_S459_S0.5310.19
142_V145_A0.5300.19
364_E514_M0.5300.19
426_W438_A0.5290.19
230_T630_K0.5290.19
243_F425_V0.5280.19
410_W435_N0.5280.19
448_P510_V0.5280.19
168_D526_T0.5280.19
259_L598_L0.5270.19
526_T559_N0.5270.19
515_G519_E0.5270.19
558_W591_L0.5260.19
283_L408_A0.5260.19
436_L441_L0.5260.19
201_R293_G0.5260.19
293_G378_Y0.5260.19
293_G457_R0.5260.19
182_Q343_H0.5250.19
220_A285_T0.5250.19
234_A371_Q0.5250.19
90_A119_D0.5250.19
110_E535_D0.5250.19
407_G589_R0.5240.19
52_P182_Q0.5240.19
182_Q598_L0.5240.19
27_G39_L0.5230.19
95_T117_D0.5230.19
62_P437_V0.5220.19
177_Q371_Q0.5220.19
213_I302_F0.5220.19
387_R583_G0.5220.19
284_L325_P0.5210.19
84_F451_A0.5210.19
138_H286_T0.5210.19
363_P381_S0.5190.18
139_L350_V0.5190.18
133_P494_F0.5180.18
501_W507_C0.5180.18
138_H333_A0.5170.18
202_G205_K0.5170.18
89_F514_M0.5170.18
220_A267_I0.5170.18
512_V537_G0.5160.18
337_D465_P0.5160.18
202_G263_E0.5150.18
204_G263_E0.5150.18
205_K263_E0.5150.18
157_P222_V0.5140.18
315_Q322_Q0.5140.18
20_R25_L0.5130.18
329_M383_L0.5120.18
325_P430_R0.5120.18
315_Q591_L0.5110.18
509_F614_G0.5090.18
482_Q549_R0.5080.18
405_I643_E0.5080.18
220_A637_L0.5080.18
288_V465_P0.5080.18
391_A495_G0.5080.18
94_G372_L0.5070.18
50_I54_P0.5070.18
70_G293_G0.5070.18
41_D156_Q0.5050.18
258_W396_F0.5050.18
73_F95_T0.5050.18
272_L435_N0.5050.18
72_E320_W0.5040.18
176_P517_H0.5040.18
338_D374_S0.5040.18
515_G599_L0.5040.18
270_P523_G0.5040.18
398_Q405_I0.5040.18
342_T578_W0.5030.18
134_H356_Q0.5020.18
352_S499_E0.5020.18
394_Q596_G0.5010.18
103_V477_I0.5010.18
360_Q398_Q0.5010.18
344_T581_L0.5000.18
28_E53_R0.5000.18
313_E548_L0.5000.18
158_F538_K0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2zpaA 1 0.9866 100 0.341 Contact Map
2reeA 1 0.2429 99.5 0.929 Contact Map
3c26A 2 0.3383 99.4 0.934 Contact Map
1z4rA 1 0.228 99.2 0.938 Contact Map
1n71A 4 0.2206 99.2 0.939 Contact Map
1kzfA 1 0.2653 99.2 0.94 Contact Map
3efaA 2 0.2116 99.2 0.94 Contact Map
4r3lA 1 0.228 99.1 0.941 Contact Map
2q0yA 2 0.2131 99.1 0.941 Contact Map
1yghA 1 0.2355 99.1 0.942 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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