GREMLIN Database
YFBP - Uncharacterized protein YfbP
UniProt: P76486 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14100
Length: 282 (215)
Sequences: 897 (843)
Seq/√Len: 57.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
115_R118_D5.9871.00
229_K232_Q5.7591.00
149_K152_A5.3331.00
107_A123_L4.9271.00
81_E84_D4.7901.00
183_D186_N4.2611.00
73_I89_E3.6581.00
141_A157_A3.4231.00
106_V122_L3.2301.00
110_C118_D2.9751.00
104_F139_A2.7581.00
221_V237_L2.7471.00
174_V178_L2.7041.00
106_V110_C2.6911.00
120_L143_Q2.3671.00
140_L144_Y2.3051.00
76_F81_E2.2751.00
89_E105_R2.0941.00
118_D121_P2.0801.00
178_L224_Y2.0521.00
120_L140_L1.9341.00
144_Y152_A1.9141.00
90_N106_V1.9021.00
76_F84_D1.9021.00
160_A170_P1.8901.00
92_I102_N1.8901.00
124_Q140_L1.8511.00
144_Y149_K1.8240.99
137_W159_N1.8040.99
154_A174_V1.8030.99
134_S141_A1.7760.99
140_L156_A1.7650.99
93_S103_L1.7570.99
66_I70_F1.7500.99
86_D90_N1.7440.99
103_L122_L1.6420.99
224_Y232_Q1.6140.99
141_A160_A1.5640.98
127_T137_W1.5300.98
77_E109_K1.4810.98
126_A129_Q1.4390.97
93_S118_D1.4150.97
100_A126_A1.4150.97
210_E213_N1.3670.96
173_K219_M1.3600.96
134_S160_A1.3560.96
74_K105_R1.3520.96
178_L186_N1.3240.95
103_L126_A1.3240.95
80_L148_K1.3210.95
123_L140_L1.3200.95
107_A122_L1.2800.94
141_A153_A1.2780.94
86_D106_V1.2410.93
220_C236_L1.2340.93
154_A158_L1.2300.93
214_Y240_Y1.2280.93
52_K55_I1.2170.93
228_R233_A1.2050.92
107_A126_A1.1920.92
175_I223_T1.1740.91
28_T31_T1.1710.91
206_G209_K1.1580.91
138_L173_K1.1530.91
46_P51_H1.1500.90
140_L220_C1.1450.90
214_Y221_V1.1450.90
217_M240_Y1.1360.90
34_A37_N1.1310.90
221_V233_A1.1290.90
217_M236_L1.1260.90
92_I95_E1.1210.89
123_L139_A1.1150.89
227_Q235_T1.1130.89
154_A177_L1.0960.88
73_I92_I1.0910.88
139_A142_I1.0800.87
29_V32_D1.0740.87
29_V34_A1.0700.87
66_I92_I1.0620.87
102_N109_K1.0580.86
161_Y170_P1.0530.86
126_A136_Y1.0490.86
31_T37_N1.0430.86
35_Y41_F1.0410.85
77_E89_E1.0400.85
193_I223_T1.0350.85
84_D87_P1.0320.85
110_C122_L1.0230.84
234_L238_H1.0050.83
76_F88_H1.0010.83
109_K113_T0.9930.83
142_I157_A0.9920.83
72_S76_F0.9910.83
161_Y174_V0.9870.82
237_L241_A0.9790.82
120_L124_Q0.9780.82
30_L34_A0.9760.82
44_Y47_I0.9630.81
151_E155_Q0.9570.80
201_L204_S0.9450.79
216_L220_C0.9440.79
158_L174_V0.9430.79
208_T212_N0.9420.79
208_T220_C0.9390.79
137_W160_A0.9380.79
194_Q197_K0.9330.79
222_D237_L0.9330.79
225_F230_P0.9270.78
120_L154_A0.9170.77
221_V240_Y0.9060.76
111_L123_L0.9030.76
236_L240_Y0.8960.76
157_A161_Y0.8940.76
70_F123_L0.8860.75
235_T239_N0.8840.75
54_P57_C0.8840.75
134_S168_G0.8840.75
36_G44_Y0.8830.75
89_E237_L0.8790.74
134_S214_Y0.8710.74
108_R139_A0.8700.74
29_V41_F0.8650.73
225_F237_L0.8620.73
103_L137_W0.8600.73
216_L226_A0.8590.73
154_A181_A0.8520.72
119_A123_L0.8460.71
147_C227_Q0.8400.71
205_F213_N0.8370.71
200_G204_S0.8300.70
124_Q128_E0.8290.70
130_L133_V0.8270.70
188_Q193_I0.8250.69
118_D186_N0.8150.69
86_D110_C0.8090.68
203_L229_K0.8070.68
154_A234_L0.8060.68
133_V137_W0.8050.68
72_S110_C0.8040.68
220_C224_Y0.8000.67
207_G211_N0.7990.67
116_L150_T0.7990.67
139_A173_K0.7950.67
28_T38_G0.7950.67
180_Q235_T0.7940.67
84_D185_P0.7910.66
54_P58_E0.7880.66
137_W156_A0.7870.66
46_P69_A0.7860.66
203_L230_P0.7850.66
121_P124_Q0.7850.66
219_M223_T0.7840.66
141_A221_V0.7800.65
36_G39_D0.7790.65
219_M222_D0.7730.64
213_N217_M0.7710.64
125_R128_E0.7660.64
120_L144_Y0.7650.64
142_I173_K0.7510.62
130_L136_Y0.7450.62
133_V136_Y0.7400.61
197_K220_C0.7390.61
31_T40_C0.7370.61
45_W49_Q0.7370.61
85_D109_K0.7300.60
35_Y40_C0.7280.60
57_C159_N0.7270.60
121_P153_A0.7250.59
28_T32_D0.7230.59
158_L211_N0.7200.59
116_L120_L0.7200.59
221_V236_L0.7180.59
32_D37_N0.7170.59
105_R125_R0.7130.58
108_R111_L0.7120.58
103_L171_D0.7120.58
218_Q221_V0.7090.58
168_G175_I0.7060.57
131_P145_R0.7040.57
117_D148_K0.7030.57
29_V37_N0.7030.57
152_A155_Q0.7020.57
223_T227_Q0.7020.57
33_A44_Y0.7010.57
110_C178_L0.6980.57
30_L36_G0.6970.56
167_F171_D0.6960.56
70_F102_N0.6950.56
121_P155_Q0.6920.56
173_K176_H0.6900.56
31_T35_Y0.6900.56
74_K89_E0.6890.56
80_L105_R0.6890.56
28_T33_A0.6880.56
160_A175_I0.6820.55
93_S175_I0.6820.55
208_T229_K0.6800.55
196_I204_S0.6780.54
138_L160_A0.6750.54
70_F73_I0.6750.54
185_P227_Q0.6720.54
47_I50_E0.6720.54
44_Y51_H0.6640.53
74_K77_E0.6630.53
32_D41_F0.6630.53
117_D147_C0.6620.53
122_L126_A0.6600.52
120_L147_C0.6570.52
47_I73_I0.6550.52
92_I126_A0.6540.52
161_Y171_D0.6530.52
89_E157_A0.6500.51
215_P221_V0.6480.51
205_F211_N0.6470.51
65_R68_P0.6470.51
140_L174_V0.6450.51
182_A187_F0.6420.50
226_A240_Y0.6410.50
208_T211_N0.6410.50
176_H219_M0.6360.50
115_R129_Q0.6330.49
31_T51_H0.6320.49
46_P54_P0.6300.49
213_N220_C0.6300.49
41_F46_P0.6280.49
242_W245_S0.6270.49
205_F245_S0.6270.49
207_G223_T0.6260.49
193_I196_I0.6250.49
207_G221_V0.6230.48
92_I109_K0.6220.48
118_D122_L0.6200.48
179_S219_M0.6170.48
46_P63_E0.6160.48
141_A156_A0.6150.48
185_P231_L0.6140.47
104_F126_A0.6130.47
172_N244_M0.6120.47
187_F241_A0.6120.47
84_D88_H0.6110.47
102_N105_R0.6110.47
173_K179_S0.6100.47
33_A41_F0.6070.47
107_A187_F0.6010.46
159_N239_N0.6010.46
213_N228_R0.6010.46
34_A38_G0.6010.46
28_T34_A0.5960.45
129_Q163_G0.5950.45
33_A37_N0.5940.45
143_Q147_C0.5910.45
70_F186_N0.5800.44
41_F48_G0.5780.43
206_G211_N0.5760.43
224_Y229_K0.5760.43
196_I210_E0.5760.43
77_E93_S0.5760.43
28_T37_N0.5750.43
157_A170_P0.5750.43
157_A184_V0.5750.43
67_V70_F0.5690.43
48_G59_T0.5690.43
37_N41_F0.5690.43
210_E216_L0.5650.42
87_P90_N0.5640.42
73_I212_N0.5620.42
244_M247_E0.5620.42
73_I85_D0.5620.42
77_E82_V0.5610.42
154_A169_V0.5590.41
35_Y39_D0.5560.41
158_L231_L0.5560.41
168_G185_P0.5560.41
85_D153_A0.5560.41
44_Y48_G0.5560.41
89_E109_K0.5500.40
158_L186_N0.5500.40
114_G224_Y0.5500.40
209_K212_N0.5490.40
39_D43_L0.5470.40
117_D120_L0.5440.40
217_M239_N0.5420.40
220_C226_A0.5420.40
60_Y125_R0.5410.40
110_C115_R0.5390.39
204_S208_T0.5380.39
35_Y38_G0.5380.39
101_A109_K0.5370.39
42_G51_H0.5350.39
28_T44_Y0.5340.39
139_A148_K0.5340.39
205_F230_P0.5340.39
53_L227_Q0.5330.39
58_E183_D0.5310.38
79_W84_D0.5300.38
83_N159_N0.5280.38
39_D70_F0.5270.38
53_L56_V0.5240.38
52_K58_E0.5220.38
106_V113_T0.5220.38
160_A163_G0.5220.38
143_Q225_F0.5210.37
77_E92_I0.5200.37
103_L129_Q0.5200.37
29_V39_D0.5190.37
142_I146_R0.5170.37
233_A237_L0.5170.37
35_Y43_L0.5170.37
174_V177_L0.5160.37
124_Q240_Y0.5130.37
207_G215_P0.5120.37
221_V230_P0.5110.36
233_A244_M0.5100.36
67_V79_W0.5100.36
188_Q221_V0.5070.36
55_I119_A0.5040.36
89_E93_S0.5030.36
57_C60_Y0.5030.36
48_G56_V0.5020.36
69_A97_Q0.5010.35
144_Y156_A0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3q7aA 1 0.8865 99.9 0.395 Contact Map
3dssA 1 0.8936 99.9 0.402 Contact Map
4l9pA 1 0.8369 99.9 0.414 Contact Map
3draA 1 0.8901 99.9 0.424 Contact Map
3urzA 1 0.6738 99.9 0.427 Contact Map
1w3bA 2 0.8901 99.9 0.429 Contact Map
4gywA 2 0.7376 99.9 0.436 Contact Map
1dceA 1 0.9397 99.9 0.438 Contact Map
2h6fA 1 0.8901 99.9 0.44 Contact Map
4ui9C 2 0.883 99.9 0.442 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0093 seconds.