GREMLIN Database
ARND - Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD
UniProt: P76472 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14092
Length: 296 (288)
Sequences: 234 (147)
Seq/√Len: 8.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_I27_L8.4681.00
29_K246_V4.8010.99
24_L101_H4.0260.98
175_G181_P3.7890.97
4_V257_V3.4550.95
37_F148_A3.3360.94
22_R25_E3.0850.91
30_H246_V3.0530.90
87_G139_I2.9050.88
13_F90_N2.7660.85
215_G251_R2.4990.79
111_H115_A2.4670.78
33_Q101_H2.3930.75
172_D192_Q2.2980.72
54_K100_H2.2730.71
105_L132_G2.2590.71
16_T87_G2.2140.69
159_I275_V2.1980.69
103_V136_L2.1840.68
124_T128_D2.0750.64
128_D131_R2.0410.63
35_S246_V2.0380.63
218_L255_E2.0240.62
4_V221_I2.0080.61
8_I268_E2.0050.61
246_V250_K1.9990.61
45_M284_E1.9290.58
13_F242_Q1.9200.58
71_G104_G1.8920.57
37_F45_M1.8680.56
61_M66_A1.8240.54
110_H233_H1.8170.53
47_R83_G1.7970.53
150_A248_L1.7960.52
191_A270_L1.7830.52
57_F60_K1.7660.51
14_R38_F1.7640.51
75_L114_Q1.7480.50
68_S101_H1.7270.50
40_V132_G1.7270.50
84_K209_K1.7230.49
79_T179_F1.7190.49
277_R288_G1.6990.48
94_I128_D1.6940.48
3_K258_T1.6690.47
204_I212_D1.5910.44
252_A257_V1.5860.44
150_A287_L1.5860.44
178_P263_S1.5620.43
163_E190_T1.5410.42
45_M50_W1.5190.41
84_K89_A1.5180.41
37_F146_C1.5170.41
135_T281_A1.5090.40
57_F110_H1.5020.40
70_Y233_H1.4740.39
127_D290_Q1.4670.39
77_A81_W1.4650.39
15_G19_G1.4510.38
13_F22_R1.4180.37
162_K170_N1.4080.36
85_E135_T1.3860.35
39_S205_G1.3720.35
147_S150_A1.3560.34
91_A256_G1.3550.34
14_R114_Q1.3530.34
49_L55_P1.3520.34
38_F97_A1.3510.34
22_R191_A1.3370.34
14_R87_G1.3350.33
130_A134_R1.3300.33
114_Q233_H1.3240.33
91_A138_E1.3190.33
160_E186_G1.3110.33
8_I245_F1.3030.32
79_T204_I1.2960.32
139_I245_F1.2930.32
112_A128_D1.2860.32
106_H110_H1.2630.31
180_R270_L1.2560.31
60_K233_H1.2400.30
196_T290_Q1.2340.30
45_M61_M1.2260.29
48_H74_I1.2240.29
19_G237_E1.2230.29
100_H200_W1.2210.29
7_R153_R1.2090.29
178_P227_T1.2060.29
94_I275_V1.2030.29
128_D188_P1.2030.29
173_C179_F1.2030.29
8_I17_R1.1970.28
169_Y266_L1.1910.28
9_D106_H1.1860.28
95_R139_I1.1690.27
199_T231_T1.1680.27
128_D254_Q1.1670.27
24_L97_A1.1490.27
258_T275_V1.1470.27
240_A243_H1.1320.26
117_S200_W1.1260.26
13_F89_A1.1240.26
29_K182_L1.1200.26
15_G43_D1.1080.25
69_L236_V1.1080.25
32_I101_H1.1080.25
76_L103_V1.1040.25
145_T168_R1.1030.25
182_L272_L1.0990.25
162_K288_G1.0950.25
26_I242_Q1.0950.25
221_I255_E1.0920.25
142_Q209_K1.0910.25
8_I139_I1.0790.25
53_V56_Q1.0760.24
79_T114_Q1.0750.24
88_H138_E1.0710.24
142_Q275_V1.0670.24
16_T38_F1.0670.24
56_Q115_A1.0640.24
160_E274_Q1.0640.24
184_E247_D1.0600.24
40_V105_L1.0450.23
244_N280_I1.0410.23
210_A241_Y1.0400.23
20_V36_I1.0400.23
111_H117_S1.0280.23
48_H115_A1.0280.23
45_M75_L1.0220.23
14_R37_F1.0070.22
132_G203_V1.0060.22
7_R74_I1.0050.22
123_Q223_R1.0050.22
138_E227_T1.0020.22
28_S33_Q0.9970.22
168_R219_N0.9960.22
45_M66_A0.9950.22
188_P272_L0.9890.22
107_A159_I0.9880.22
158_V275_V0.9840.22
196_T275_V0.9830.22
118_G286_W0.9780.21
145_T263_S0.9780.21
146_C163_E0.9750.21
12_T19_G0.9750.21
70_Y114_Q0.9720.21
89_A100_H0.9690.21
7_R286_W0.9640.21
126_I130_A0.9640.21
126_I164_A0.9630.21
14_R55_P0.9620.21
216_W220_R0.9570.21
87_G240_A0.9570.21
5_G286_W0.9570.21
224_D228_P0.9550.21
45_M83_G0.9510.21
137_E163_E0.9490.21
11_D106_H0.9410.20
60_K110_H0.9400.20
37_F48_H0.9380.20
65_N279_N0.9370.20
120_W266_L0.9330.20
101_H261_P0.9320.20
73_D105_L0.9300.20
116_R119_N0.9280.20
237_E283_R0.9270.20
74_I136_L0.9270.20
28_S96_E0.9260.20
93_I96_E0.9210.20
178_P196_T0.9190.20
177_M290_Q0.9190.20
74_I115_A0.9160.20
134_R137_E0.9110.20
77_A84_K0.9110.20
230_Y267_S0.9100.20
137_E210_A0.9100.20
180_R272_L0.9100.20
17_R27_L0.9090.20
37_F44_N0.9070.19
145_T254_Q0.9050.19
108_W173_C0.9000.19
30_H250_K0.9000.19
182_L289_C0.9000.19
206_R210_A0.8960.19
154_A159_I0.8940.19
120_W288_G0.8900.19
66_A107_A0.8900.19
29_K35_S0.8890.19
160_E164_A0.8870.19
25_E96_E0.8860.19
100_H117_S0.8830.19
6_L10_V0.8830.19
14_R150_A0.8810.19
213_F241_Y0.8790.19
48_H81_W0.8780.19
160_E184_E0.8770.19
123_Q211_E0.8760.19
28_S99_K0.8740.19
74_I81_W0.8740.19
45_M48_H0.8700.19
54_K274_Q0.8660.18
60_K70_Y0.8630.18
44_N61_M0.8630.18
15_G235_E0.8620.18
39_S278_G0.8520.18
99_K124_T0.8500.18
9_D46_G0.8490.18
62_L259_F0.8480.18
250_K275_V0.8440.18
37_F66_A0.8400.18
4_V229_V0.8370.18
264_E274_Q0.8350.18
280_I289_C0.8330.18
220_R281_A0.8330.18
152_W238_G0.8320.18
145_T268_E0.8320.18
121_D124_T0.8320.18
105_L163_E0.8320.18
133_L247_D0.8240.17
111_H284_E0.8230.17
256_G281_A0.8210.17
88_H166_H0.8210.17
191_A228_P0.8180.17
188_P264_E0.8150.17
54_K134_R0.8090.17
31_N138_E0.8080.17
118_G277_R0.8030.17
141_G166_H0.8020.17
95_R121_D0.8000.17
162_K230_Y0.7980.17
65_N223_R0.7950.17
131_R279_N0.7920.17
138_E258_T0.7870.16
90_N128_D0.7850.16
121_D246_V0.7840.16
37_F284_E0.7820.16
4_V220_R0.7810.16
75_L104_G0.7760.16
277_R286_W0.7710.16
201_D231_T0.7660.16
51_R63_R0.7640.16
87_G91_A0.7610.16
47_R128_D0.7610.16
4_V249_L0.7580.16
203_V216_W0.7560.16
177_M239_C0.7550.16
97_A240_A0.7510.16
81_W195_V0.7510.16
75_L287_L0.7470.16
27_L215_G0.7460.16
22_R56_Q0.7450.16
183_L186_G0.7440.15
55_P75_L0.7430.15
6_L23_L0.7420.15
215_G219_N0.7420.15
45_M148_A0.7390.15
111_H239_C0.7360.15
72_W216_W0.7360.15
118_G230_Y0.7350.15
260_C289_C0.7340.15
117_S125_M0.7340.15
148_A284_E0.7320.15
51_R201_D0.7280.15
139_I234_A0.7270.15
26_I29_K0.7260.15
155_D277_R0.7250.15
30_H35_S0.7250.15
95_R272_L0.7240.15
254_Q269_T0.7200.15
12_T15_G0.7170.15
88_H258_T0.7170.15
109_D233_H0.7160.15
196_T200_W0.7150.15
45_M146_C0.7150.15
106_H233_H0.7120.15
21_P82_P0.7110.15
134_R281_A0.7090.15
162_K287_L0.7070.15
99_K119_N0.7070.15
114_Q287_L0.7070.15
77_A154_A0.7050.15
86_I199_T0.7030.15
58_L76_L0.7030.15
253_A258_T0.7030.15
152_W202_E0.7020.15
112_A115_A0.7010.15
110_H114_Q0.7000.15
40_V91_A0.7000.15
146_C165_F0.6990.15
64_S205_G0.6980.14
47_R112_A0.6980.14
142_Q223_R0.6970.14
143_P253_A0.6960.14
38_F150_A0.6950.14
211_E253_A0.6950.14
22_R242_Q0.6930.14
28_S101_H0.6910.14
134_R167_L0.6880.14
217_L290_Q0.6870.14
151_G248_L0.6870.14
141_G177_M0.6840.14
177_M219_N0.6840.14
40_V45_M0.6820.14
101_H257_V0.6790.14
217_L255_E0.6780.14
7_R50_W0.6770.14
131_R276_V0.6750.14
62_L66_A0.6710.14
189_G267_S0.6710.14
134_R253_A0.6710.14
116_R200_W0.6670.14
172_D199_T0.6660.14
37_F61_M0.6630.14
55_P114_Q0.6620.14
25_E49_L0.6610.14
125_M150_A0.6600.14
70_Y110_H0.6560.14
70_Y106_H0.6560.14
136_L204_I0.6540.14
7_R236_V0.6540.14
159_I288_G0.6540.14
28_S156_Q0.6520.14
31_N247_D0.6460.13
26_I30_H0.6460.13
219_N251_R0.6450.13
237_E282_G0.6420.13
135_T138_E0.6410.13
42_P57_F0.6380.13
152_W237_E0.6370.13
71_G233_H0.6340.13
187_N272_L0.6330.13
247_D254_Q0.6330.13
146_C167_L0.6330.13
154_A158_V0.6330.13
131_R160_E0.6320.13
12_T70_Y0.6320.13
125_M230_Y0.6300.13
71_G110_H0.6280.13
185_S253_A0.6270.13
198_P234_A0.6240.13
3_K22_R0.6240.13
224_D227_T0.6210.13
200_W278_G0.6190.13
13_F185_S0.6170.13
196_T221_I0.6150.13
57_F205_G0.6090.13
7_R284_E0.6080.13
97_A107_A0.6030.13
88_H268_E0.6000.13
12_T57_F0.5980.12
70_Y169_Y0.5960.12
45_M74_I0.5950.12
5_G175_G0.5950.12
258_T278_G0.5910.12
89_A200_W0.5900.12
18_E270_L0.5890.12
207_D213_F0.5870.12
189_G230_Y0.5860.12
69_L148_A0.5830.12
13_F183_L0.5800.12
126_I269_T0.5800.12
81_W115_A0.5790.12
156_Q184_E0.5790.12
94_I278_G0.5740.12
173_C288_G0.5730.12
24_L28_S0.5730.12
89_A94_I0.5730.12
251_R255_E0.5720.12
87_G95_R0.5720.12
37_F114_Q0.5710.12
156_Q211_E0.5710.12
19_G152_W0.5700.12
156_Q187_N0.5700.12
63_R205_G0.5670.12
115_A213_F0.5660.12
141_G168_R0.5650.12
30_H121_D0.5650.12
160_E279_N0.5650.12
3_K50_W0.5630.12
207_D210_A0.5620.12
139_I278_G0.5600.12
214_N265_L0.5590.12
168_R178_P0.5580.12
13_F91_A0.5580.12
179_F286_W0.5550.12
219_N255_E0.5530.12
217_L278_G0.5500.12
182_L253_A0.5470.12
54_K93_I0.5470.12
177_M227_T0.5460.12
92_D279_N0.5450.12
175_G280_I0.5440.12
100_H280_I0.5410.11
117_S150_A0.5400.11
74_I195_V0.5400.11
57_F233_H0.5380.11
196_T246_V0.5320.11
161_A278_G0.5300.11
44_N50_W0.5300.11
33_Q275_V0.5280.11
183_L230_Y0.5240.11
196_T243_H0.5230.11
230_Y245_F0.5230.11
58_L186_G0.5230.11
51_R287_L0.5130.11
130_A250_K0.5130.11
40_V170_N0.5120.11
28_S145_T0.5120.11
229_V249_L0.5110.11
7_R115_A0.5110.11
123_Q150_A0.5110.11
57_F106_H0.5110.11
154_A287_L0.5110.11
124_T251_R0.5100.11
226_G260_C0.5090.11
7_R48_H0.5090.11
7_R136_L0.5090.11
166_H275_V0.5080.11
135_T158_V0.5080.11
129_I165_F0.5070.11
29_K243_H0.5070.11
168_R263_S0.5060.11
16_T45_M0.5060.11
28_S225_K0.5060.11
109_D152_W0.5060.11
17_R95_R0.5050.11
31_N123_Q0.5040.11
124_T232_I0.5030.11
206_R223_R0.5020.11
35_S87_G0.5020.11
57_F64_S0.5010.11
135_T154_A0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ly4A 3 0.7669 100 0.785 Contact Map
3rxzA 3 0.7804 100 0.79 Contact Map
3hftA 2 0.7162 99.9 0.81 Contact Map
3s6oA 3 0.7466 99.9 0.813 Contact Map
3cl6A 3 0.75 99.9 0.819 Contact Map
1ny1A 1 0.6385 99.9 0.83 Contact Map
2j13A 1 0.5777 99.9 0.831 Contact Map
2vyoA 1 0.6385 99.9 0.833 Contact Map
4m1bA 1 0.6351 99.9 0.835 Contact Map
2w3zA 1 0.6486 99.9 0.836 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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