RTN - ECOLI - GREMLIN Contacts

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RTN - Protein Rtn

UniProt:	P76446	Sequences: MFIRAPNFGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVRWLKKPYTPQW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14077
Length:	518 (437)
Sequences:	19284 (15266)
Seq/√Len:	730.3

ECOLI - RTN DOSP YEGE YLIE YFGF YHJK CSRD YFEA GMR YLAB YJCC YCGG ADRB BLUF YAHA
BACSU - YKOW YKUI

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
295_L	506_F	4.076	1.00
287_T	492_M	3.906	1.00
95_T	99_V	3.649	1.00
329_Q	369_D	3.372	1.00
328_T	360_H	3.265	1.00
371_Q	409_V	3.172	1.00
440_R	444_N	3.151	1.00
333_E	376_S	3.026	1.00
498_S	501_L	2.928	1.00
278_Y	302_R	2.907	1.00
281_Y	338_D	2.896	1.00
407_H	434_D	2.891	1.00
385_V	435_Y	2.793	1.00
260_V	313_A	2.771	1.00
286_D	289_A	2.701	1.00
340_A	344_K	2.534	1.00
169_L	172_S	2.524	1.00
483_W	487_R	2.517	1.00
464_K	490_N	2.491	1.00
343_E	383_Q	2.480	1.00
478_P	482_R	2.442	1.00
267_E	303_H	2.360	1.00
111_G	183_D	2.235	1.00
481_A	497_I	2.222	1.00
429_E	452_T	2.194	1.00
330_H	334_L	2.167	1.00
303_H	307_G	2.162	1.00
338_D	503_L	2.147	1.00
414_A	435_Y	2.111	1.00
475_V	492_M	2.097	1.00
457_D	465_R	2.083	1.00
318_A	327_L	2.073	1.00
334_L	337_R	2.060	1.00
299_L	331_L	1.986	1.00
106_C	110_T	1.985	1.00
261_R	320_S	1.980	1.00
270_T	274_R	1.969	1.00
131_D	226_L	1.936	1.00
302_R	308_E	1.935	1.00
115_I	233_W	1.931	1.00
336_A	373_L	1.931	1.00
334_L	338_D	1.891	1.00
477_T	480_Q	1.879	1.00
453_S	483_W	1.871	1.00
275_E	334_L	1.868	1.00
481_A	492_M	1.857	1.00
280_A	502_P	1.822	1.00
278_Y	308_E	1.821	1.00
133_A	222_L	1.810	1.00
232_T	235_D	1.809	1.00
356_I	366_F	1.800	1.00
133_A	198_S	1.799	1.00
284_V	491_F	1.793	1.00
338_D	342_L	1.792	1.00
403_F	413_I	1.783	1.00
373_L	377_L	1.755	1.00
380_H	383_Q	1.753	1.00
279_V	331_L	1.743	1.00
457_D	487_R	1.732	1.00
502_P	505_D	1.715	1.00
351_K	412_E	1.715	1.00
86_R	90_S	1.709	1.00
285_V	497_I	1.708	1.00
339_A	379_A	1.695	1.00
303_H	306_A	1.680	1.00
284_V	435_Y	1.672	1.00
385_V	414_A	1.665	1.00
333_E	373_L	1.651	1.00
435_Y	471_V	1.648	1.00
481_A	485_S	1.644	1.00
333_E	377_L	1.633	1.00
447_G	453_S	1.625	1.00
110_T	114_D	1.625	1.00
138_T	221_P	1.617	1.00
154_P	159_S	1.610	1.00
478_P	496_W	1.605	1.00
412_E	434_D	1.589	1.00
436_L	463_A	1.587	1.00
457_D	461_T	1.575	1.00
144_K	152_R	1.567	1.00
280_A	308_E	1.559	1.00
276_Q	303_H	1.558	1.00
374_L	411_V	1.554	1.00
460_L	487_R	1.534	1.00
247_G	256_Y	1.531	1.00
277_F	299_L	1.531	1.00
481_A	496_W	1.528	1.00
284_V	385_V	1.525	1.00
114_D	175_Y	1.524	1.00
160_G	209_D	1.518	1.00
469_L	490_N	1.517	1.00
342_L	503_L	1.514	1.00
460_L	489_V	1.505	1.00
250_V	256_Y	1.503	1.00
447_G	479_E	1.498	1.00
351_K	385_V	1.493	1.00
469_L	491_F	1.487	1.00
210_M	215_T	1.485	1.00
100_K	176_S	1.473	1.00
495_Y	500_P	1.468	1.00
415_I	433_L	1.463	1.00
293_T	491_F	1.446	1.00
356_I	386_L	1.438	1.00
345_V	507_V	1.433	1.00
279_V	330_H	1.431	1.00
78_Q	82_E	1.429	1.00
284_V	294_G	1.425	1.00
160_G	163_A	1.421	1.00
139_P	252_L	1.404	1.00
429_E	445_A	1.398	1.00
501_L	509_W	1.397	1.00
343_E	380_H	1.378	1.00
131_D	194_L	1.377	1.00
299_L	327_L	1.367	1.00
154_P	212_V	1.360	1.00
163_A	166_N	1.337	1.00
372_K	376_S	1.330	1.00
177_S	183_D	1.330	1.00
435_Y	469_L	1.328	1.00
440_R	474_G	1.322	1.00
447_G	483_W	1.318	1.00
157_K	218_A	1.316	1.00
95_T	104_T	1.310	1.00
92_N	96_F	1.309	1.00
337_R	377_L	1.297	1.00
94_R	98_L	1.290	1.00
116_P	233_W	1.284	1.00
341_E	345_V	1.280	1.00
276_Q	301_W	1.275	1.00
292_V	509_W	1.272	1.00
505_D	508_R	1.267	1.00
79_A	82_E	1.267	1.00
472_A	489_V	1.258	1.00
371_Q	405_W	1.257	1.00
374_L	381_H	1.250	1.00
161_V	205_N	1.249	1.00
400_T	404_A	1.247	1.00
111_G	175_Y	1.245	1.00
114_D	173_L	1.244	1.00
335_I	352_F	1.243	1.00
299_L	330_H	1.238	1.00
325_V	363_S	1.229	1.00
86_R	89_F	1.228	1.00
369_D	373_L	1.221	1.00
246_S	249_V	1.220	1.00
114_D	118_N	1.218	1.00
463_A	470_T	1.218	1.00
260_V	306_A	1.218	1.00
267_E	306_A	1.217	1.00
446_I	483_W	1.214	1.00
270_T	276_Q	1.210	1.00
72_T	82_E	1.207	1.00
306_A	313_A	1.198	1.00
339_A	352_F	1.198	1.00
482_R	485_S	1.187	1.00
400_T	430_R	1.181	1.00
492_M	497_I	1.168	1.00
349_G	383_Q	1.168	1.00
160_G	164_A	1.163	1.00
75_T	78_Q	1.155	1.00
342_L	507_V	1.151	1.00
338_D	341_E	1.147	1.00
186_A	197_F	1.144	1.00
204_V	207_L	1.143	1.00
247_G	254_C	1.143	1.00
286_D	291_R	1.140	1.00
385_V	412_E	1.139	1.00
235_D	239_A	1.138	1.00
135_L	220_I	1.134	1.00
433_L	468_M	1.134	1.00
205_N	220_I	1.132	1.00
287_T	481_A	1.130	1.00
482_R	486_E	1.127	1.00
286_D	293_T	1.127	1.00
284_V	353_G	1.126	1.00
168_N	174_F	1.125	1.00
129_N	229_D	1.125	1.00
498_S	509_W	1.123	1.00
105_F	162_F	1.118	1.00
77_Q	80_N	1.117	1.00
367_K	371_Q	1.116	1.00
446_I	456_L	1.112	1.00
134_I	183_D	1.110	1.00
194_L	198_S	1.106	1.00
371_Q	375_T	1.105	1.00
277_F	330_H	1.101	1.00
139_P	142_P	1.098	1.00
199_S	203_N	1.097	1.00
87_A	90_S	1.097	1.00
99_V	110_T	1.095	1.00
404_A	408_S	1.093	1.00
358_P	391_R	1.092	1.00
137_G	161_V	1.092	1.00
82_E	86_R	1.087	1.00
225_R	239_A	1.084	1.00
353_G	385_V	1.083	1.00
264_P	317_F	1.081	1.00
370_I	406_L	1.079	1.00
198_S	224_V	1.075	1.00
290_L	485_S	1.075	1.00
340_A	343_E	1.074	1.00
304_P	307_G	1.074	1.00
447_G	477_T	1.069	1.00
195_S	257_L	1.063	1.00
154_P	160_G	1.062	1.00
362_H	395_K	1.057	1.00
142_P	265_G	1.055	1.00
478_P	481_A	1.054	1.00
461_T	465_R	1.048	1.00
195_S	199_S	1.045	1.00
224_V	257_L	1.041	1.00
435_Y	491_F	1.040	1.00
333_E	337_R	1.036	1.00
294_G	351_K	1.031	1.00
284_V	351_K	1.030	1.00
501_L	505_D	1.029	1.00
263_R	267_E	1.028	1.00
370_I	386_L	1.028	1.00
339_A	343_E	1.023	1.00
311_P	314_F	1.023	1.00
458_A	465_R	1.023	1.00
340_A	377_L	1.019	1.00
246_S	250_V	1.019	1.00
312_D	440_R	1.019	1.00
278_Y	502_P	1.015	1.00
76_C	79_A	1.014	1.00
268_I	318_A	1.009	1.00
336_A	384_I	1.003	1.00
190_G	193_A	1.001	1.00
78_Q	84_T	1.001	1.00
202_M	222_L	0.999	1.00
164_A	209_D	0.996	1.00
449_E	452_T	0.995	1.00
321_Q	325_V	0.994	1.00
367_K	405_W	0.994	1.00
130_V	227_Y	0.991	1.00
367_K	402_L	0.991	1.00
136_P	248_T	0.985	1.00
92_N	95_T	0.984	1.00
279_V	335_I	0.982	1.00
398_E	402_L	0.982	1.00
134_I	244_G	0.980	1.00
202_M	255_Y	0.978	1.00
227_Y	236_V	0.975	1.00
246_S	256_Y	0.972	1.00
98_L	113_M	0.972	1.00
98_L	109_A	0.971	1.00
85_A	88_A	0.964	1.00
335_I	354_I	0.962	1.00
144_K	179_Q	0.961	1.00
285_V	509_W	0.959	1.00
386_L	411_V	0.956	1.00
405_W	408_S	0.956	1.00
340_A	378_P	0.953	1.00
303_H	309_I	0.953	1.00
483_W	486_E	0.951	1.00
337_R	341_E	0.950	1.00
284_V	471_V	0.949	1.00
503_L	507_V	0.947	1.00
319_E	324_I	0.943	1.00
110_T	113_M	0.942	1.00
286_D	490_N	0.940	1.00
454_P	465_R	0.939	1.00
273_K	326_P	0.928	1.00
326_P	329_Q	0.928	1.00
306_A	309_I	0.924	1.00
265_G	269_M	0.921	1.00
267_E	305_V	0.919	1.00
83_L	86_R	0.919	1.00
75_T	82_E	0.918	1.00
460_L	470_T	0.914	1.00
206_E	253_L	0.913	1.00
288_Q	490_N	0.912	1.00
296_E	355_N	0.912	1.00
332_F	373_L	0.909	1.00
75_T	80_N	0.908	1.00
151_Y	154_P	0.908	1.00
447_G	480_Q	0.907	1.00
112_E	234_N	0.907	1.00
394_L	427_Y	0.904	1.00
270_T	273_K	0.902	1.00
402_L	405_W	0.901	1.00
159_S	163_A	0.900	1.00
338_D	507_V	0.899	1.00
366_F	370_I	0.898	1.00
373_L	376_S	0.898	1.00
315_I	324_I	0.897	1.00
90_S	94_R	0.896	1.00
471_V	491_F	0.895	1.00
210_M	213_R	0.893	1.00
205_N	209_D	0.892	1.00
88_A	92_N	0.891	1.00
275_E	330_H	0.888	1.00
122_P	187_L	0.888	1.00
323_M	326_P	0.887	1.00
71_L	75_T	0.887	1.00
276_Q	304_P	0.886	1.00
110_T	173_L	0.885	1.00
137_G	220_I	0.884	1.00
279_V	299_L	0.880	1.00
119_E	187_L	0.880	1.00
136_P	180_E	0.879	1.00
297_V	352_F	0.878	1.00
101_D	109_A	0.876	1.00
130_V	185_V	0.873	1.00
365_S	369_D	0.873	1.00
275_E	333_E	0.870	1.00
150_W	234_N	0.866	1.00
165_L	174_F	0.865	1.00
168_N	172_S	0.864	1.00
219_G	253_L	0.861	1.00
151_Y	214_E	0.861	1.00
211_P	216_K	0.860	1.00
78_Q	81_P	0.859	1.00
363_S	369_D	0.852	1.00
230_D	257_L	0.850	1.00
144_K	153_N	0.849	1.00
197_F	200_R	0.848	1.00
368_A	405_W	0.847	1.00
76_C	80_N	0.847	1.00
223_T	240_F	0.844	1.00
203_N	206_E	0.840	1.00
133_A	186_A	0.838	1.00
295_L	350_V	0.837	1.00
82_E	87_A	0.836	1.00
72_T	75_T	0.835	1.00
460_L	464_K	0.835	1.00
167_L	204_V	0.834	1.00
235_D	238_Y	0.833	1.00
215_T	270_T	0.832	1.00
89_F	92_N	0.831	1.00
250_V	254_C	0.830	1.00
332_F	370_I	0.828	1.00
119_E	130_V	0.826	1.00
198_S	202_M	0.826	1.00
271_A	276_Q	0.824	1.00
112_E	116_P	0.822	1.00
329_Q	373_L	0.821	1.00
401_Q	405_W	0.820	1.00
351_K	383_Q	0.818	1.00
75_T	79_A	0.818	1.00
271_A	277_F	0.817	1.00
157_K	209_D	0.817	1.00
279_V	297_V	0.814	1.00
444_N	480_Q	0.813	1.00
288_Q	485_S	0.812	1.00
135_L	184_G	0.809	1.00
106_C	173_L	0.808	1.00
98_L	110_T	0.808	1.00
269_M	323_M	0.808	1.00
268_I	277_F	0.807	1.00
77_Q	82_E	0.806	1.00
379_A	384_I	0.800	1.00
325_V	360_H	0.799	1.00
83_L	87_A	0.798	1.00
336_A	379_A	0.795	1.00
329_Q	333_E	0.793	1.00
198_S	255_Y	0.790	1.00
368_A	372_K	0.787	1.00
475_V	484_L	0.785	1.00
369_D	372_K	0.785	1.00
195_S	255_Y	0.784	1.00
464_K	470_T	0.783	1.00
387_E	437_K	0.782	1.00
281_Y	295_L	0.781	1.00
76_C	82_E	0.779	1.00
139_P	265_G	0.776	1.00
115_I	185_V	0.775	1.00
341_E	344_K	0.775	1.00
400_T	432_T	0.774	1.00
167_L	200_R	0.773	1.00
75_T	81_P	0.773	1.00
341_E	503_L	0.767	1.00
318_A	324_I	0.767	1.00
91_M	94_R	0.767	1.00
138_T	252_L	0.766	1.00
461_T	464_K	0.765	1.00
299_L	314_F	0.764	1.00
223_T	243_G	0.763	1.00
364_E	398_E	0.763	1.00
336_A	377_L	0.762	1.00
225_R	236_V	0.761	1.00
73_L	77_Q	0.761	1.00
285_V	292_V	0.760	1.00
143_N	152_R	0.760	1.00
281_Y	297_V	0.759	1.00
429_E	455_V	0.757	1.00
412_E	469_L	0.755	1.00
430_R	451_I	0.750	1.00
404_A	432_T	0.750	1.00
141_V	145_P	0.749	1.00
265_G	321_Q	0.748	1.00
198_S	222_L	0.746	1.00
321_Q	324_I	0.744	1.00
484_L	489_V	0.743	1.00
269_M	326_P	0.741	1.00
417_D	473_E	0.741	1.00
475_V	481_A	0.741	1.00
297_V	335_I	0.740	1.00
149_I	241_L	0.739	1.00
251_G	254_C	0.737	1.00
332_F	354_I	0.737	1.00
162_F	174_F	0.736	1.00
454_P	457_D	0.735	1.00
265_G	317_F	0.735	1.00
110_T	175_Y	0.734	1.00
389_T	417_D	0.733	1.00
89_F	93_V	0.731	1.00
472_A	484_L	0.729	1.00
401_Q	404_A	0.729	1.00
445_A	452_T	0.727	1.00
102_K	159_S	0.726	1.00
241_L	245_M	0.725	1.00
194_L	226_L	0.723	1.00
133_A	184_G	0.720	1.00
111_G	115_I	0.720	1.00
281_Y	503_L	0.719	1.00
93_V	96_F	0.718	1.00
445_A	448_T	0.718	1.00
168_N	184_G	0.717	1.00
136_P	245_M	0.717	1.00
71_L	82_E	0.716	1.00
290_L	481_A	0.716	1.00
225_R	240_F	0.714	1.00
221_P	252_L	0.712	1.00
272_I	330_H	0.710	1.00
453_S	457_D	0.709	1.00
134_I	240_F	0.707	1.00
283_P	498_S	0.707	1.00
74_D	78_Q	0.706	1.00
113_M	118_N	0.705	1.00
72_T	76_C	0.705	1.00
199_S	202_M	0.702	1.00
443_I	446_I	0.701	1.00
140_M	158_N	0.700	1.00
73_L	76_C	0.699	1.00
443_I	472_A	0.697	1.00
418_F	459_V	0.697	1.00
343_E	349_G	0.696	1.00
98_L	106_C	0.694	1.00
147_I	214_E	0.693	1.00
114_D	119_E	0.691	1.00
99_V	106_C	0.691	1.00
495_Y	499_R	0.690	1.00
143_N	157_K	0.689	1.00
87_A	91_M	0.687	1.00
138_T	219_G	0.687	1.00
112_E	233_W	0.685	1.00
179_Q	245_M	0.682	1.00
452_T	480_Q	0.681	1.00
384_I	411_V	0.678	1.00
169_L	197_F	0.677	1.00
139_P	320_S	0.677	1.00
76_C	81_P	0.676	1.00
183_D	237_W	0.674	1.00
324_I	359_D	0.674	1.00
226_L	257_L	0.673	1.00
147_I	216_K	0.673	1.00
302_R	307_G	0.673	1.00
111_G	185_V	0.672	1.00
343_E	346_L	0.671	1.00
450_T	453_S	0.669	1.00
283_P	501_L	0.667	1.00
135_L	222_L	0.666	1.00
116_P	121_I	0.666	1.00
361_L	402_L	0.666	1.00
178_R	181_D	0.665	1.00
354_I	384_I	0.664	1.00
312_D	316_N	0.664	1.00
134_I	177_S	0.664	1.00
398_E	401_Q	0.663	1.00
169_L	200_R	0.662	1.00
161_V	165_L	0.661	1.00
72_T	78_Q	0.661	1.00
181_D	241_L	0.661	1.00
310_P	313_A	0.660	1.00
133_A	224_V	0.660	1.00
151_Y	211_P	0.658	1.00
460_L	484_L	0.656	1.00
374_L	377_L	0.656	1.00
361_L	392_D	0.652	1.00
95_T	98_L	0.652	1.00
196_T	200_R	0.651	1.00
341_E	507_V	0.649	1.00
164_A	208_T	0.648	1.00
506_F	509_W	0.648	1.00
318_A	322_K	0.648	1.00
280_A	302_R	0.647	1.00
140_M	152_R	0.647	1.00
151_Y	216_K	0.642	1.00
128_K	188_I	0.642	1.00
283_P	292_V	0.641	1.00
193_A	196_T	0.640	1.00
140_M	144_K	0.640	1.00
268_I	323_M	0.640	1.00
136_P	144_K	0.636	1.00
161_V	209_D	0.636	1.00
470_T	490_N	0.636	1.00
285_V	290_L	0.632	1.00
347_P	350_V	0.632	1.00
295_L	352_F	0.632	1.00
180_E	248_T	0.631	1.00
368_A	371_Q	0.631	1.00
420_T	442_F	0.628	1.00
476_E	495_Y	0.627	1.00
108_S	112_E	0.627	1.00
141_V	245_M	0.627	1.00
367_K	409_V	0.622	1.00
78_Q	83_L	0.622	1.00
443_I	456_L	0.621	1.00
166_N	174_F	0.619	1.00
438_I	489_V	0.615	1.00
268_I	271_A	0.614	1.00
501_L	506_F	0.613	1.00
453_S	487_R	0.613	1.00
124_L	231_W	0.610	1.00
339_A	383_Q	0.610	1.00
290_L	478_P	0.608	1.00
130_V	236_V	0.607	1.00
73_L	80_N	0.607	1.00
278_Y	504_D	0.607	1.00
189_I	194_L	0.604	1.00
194_L	224_V	0.604	1.00
287_T	485_S	0.603	1.00
342_L	506_F	0.603	1.00
167_L	197_F	0.600	1.00
263_R	306_A	0.600	1.00
228_A	239_A	0.599	1.00
239_A	258_M	0.598	1.00
184_G	201_L	0.598	1.00
268_I	327_L	0.597	1.00
484_L	492_M	0.594	1.00
109_A	112_E	0.594	1.00
72_T	84_T	0.593	1.00
374_L	379_A	0.592	1.00
333_E	369_D	0.592	1.00
506_F	510_L	0.592	1.00
329_Q	372_K	0.592	1.00
370_I	411_V	0.591	1.00
352_F	379_A	0.588	1.00
350_V	383_Q	0.588	1.00
339_A	349_G	0.588	1.00
459_V	463_A	0.587	1.00
128_K	187_L	0.586	1.00
386_L	413_I	0.586	1.00
420_T	441_G	0.585	1.00
102_K	153_N	0.585	1.00
429_E	449_E	0.580	1.00
217_I	269_M	0.580	1.00
80_N	84_T	0.579	1.00
436_L	468_M	0.579	1.00
445_A	449_E	0.579	1.00
412_E	435_Y	0.578	1.00
255_Y	258_M	0.577	1.00
224_V	255_Y	0.577	1.00
71_L	78_Q	0.576	1.00
267_E	270_T	0.575	1.00
415_I	427_Y	0.574	1.00
329_Q	363_S	0.574	1.00
112_E	237_W	0.573	1.00
84_T	88_A	0.571	1.00
263_R	305_V	0.570	1.00
370_I	373_L	0.570	1.00
186_A	194_L	0.570	1.00
358_P	392_D	0.569	1.00
202_M	220_I	0.569	1.00
172_S	186_A	0.569	1.00
71_L	74_D	0.567	1.00
403_F	432_T	0.566	1.00
167_L	201_L	0.566	1.00
231_W	235_D	0.565	1.00
379_A	383_Q	0.563	1.00
355_N	437_K	0.562	1.00
71_L	79_A	0.562	1.00
405_W	409_V	0.562	1.00
172_S	197_F	0.562	1.00
329_Q	360_H	0.561	1.00
389_T	473_E	0.560	1.00
208_T	215_T	0.559	1.00
325_V	329_Q	0.558	1.00
189_I	193_A	0.558	1.00
355_N	416_D	0.557	1.00
147_I	151_Y	0.556	1.00
77_Q	81_P	0.555	1.00
202_M	253_L	0.554	1.00
264_P	267_E	0.554	1.00
339_A	384_I	0.554	1.00
267_E	301_W	0.553	1.00
230_D	239_A	0.552	1.00
280_A	500_P	0.550	1.00
150_W	212_V	0.549	1.00
309_I	316_N	0.549	1.00
221_P	247_G	0.548	1.00
454_P	458_A	0.548	1.00
150_W	238_Y	0.547	1.00
85_A	89_F	0.547	1.00
390_E	419_G	0.545	1.00
90_S	93_V	0.544	1.00
108_S	153_N	0.544	1.00
327_L	331_L	0.543	1.00
192_T	195_S	0.542	1.00
359_D	362_H	0.541	1.00
413_I	434_D	0.539	1.00
79_A	83_L	0.539	1.00
123_A	126_I	0.538	1.00
76_C	84_T	0.537	1.00
114_D	185_V	0.537	1.00
262_M	266_R	0.537	1.00
296_E	437_K	0.536	1.00
277_F	301_W	0.536	1.00
209_D	218_A	0.535	1.00
298_L	355_N	0.535	1.00
164_A	204_V	0.532	1.00
438_I	459_V	0.531	1.00
302_R	306_A	0.530	1.00
427_Y	430_R	0.530	1.00
497_I	500_P	0.530	1.00
260_V	264_P	0.529	1.00
294_G	353_G	0.529	1.00
455_V	459_V	0.529	1.00
75_T	83_L	0.528	1.00
328_T	331_L	0.527	1.00
119_E	122_P	0.527	1.00
202_M	206_E	0.526	1.00
73_L	78_Q	0.526	1.00
394_L	399_A	0.525	1.00
332_F	356_I	0.524	1.00
372_K	375_T	0.524	1.00
254_C	258_M	0.524	1.00
406_L	411_V	0.523	1.00
429_E	451_I	0.521	1.00
75_T	84_T	0.520	1.00
339_A	377_L	0.520	1.00
71_L	76_C	0.520	1.00
296_E	416_D	0.519	1.00
272_I	327_L	0.518	1.00
150_W	154_P	0.516	1.00
72_T	80_N	0.516	1.00
426_I	441_G	0.515	1.00
507_V	510_L	0.514	1.00
427_Y	431_F	0.510	1.00
332_F	336_A	0.508	1.00
462_L	466_L	0.505	1.00
203_N	207_L	0.505	1.00
267_E	304_P	0.505	1.00
120_L	227_Y	0.504	1.00
76_C	83_L	0.504	1.00
123_A	227_Y	0.504	1.00
450_T	454_P	0.503	0.99
149_I	152_R	0.503	0.99
290_L	497_I	0.503	0.99
451_I	467_N	0.501	0.99
340_A	379_A	0.501	0.99
105_F	174_F	0.501	0.99
118_N	187_L	0.501	0.99
479_E	482_R	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.7857	100	0.205	Contact Map
4j40A	2	0.473	100	0.217	Contact Map
3pjxA	1	0.7973	100	0.223	Contact Map
3gfzA	2	0.7143	100	0.353	Contact Map
4hjfA	1	0.4961	100	0.396	Contact Map
4kieA	1	0.5019	100	0.468	Contact Map
4hu4A	1	0.473	100	0.469	Contact Map
3sy8A	6	0.7606	100	0.471	Contact Map
4rniA	2	0.4865	100	0.476	Contact Map
2r6oA	2	0.4942	100	0.478	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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