YEGI - ECOLI - GREMLIN Contacts

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YEGI - Uncharacterized protein YegI

UniProt:	P76393	Sequences: MKTNIKVFTSTGELTTLGRELGKGGEGAVYDIEEFVDSVAKIYHTPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDSDSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTENHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDITHFRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMFQQAFTESGVATGRPTAKAWVAALDSLRQQLKKCIVSAMHVYPAHLTDCPWCALDNQGVIYFIDLGEEVITTGGNFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYIILLEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKAYKAEVQQRREAFNRAKMDYDHLVRQIQQVGGLEGFIAKRTMLEKMKDEILGLPEEEKRALAALHDTARERQKQKFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWKASCERRFVFRPNEAITPADRQAVMAKMTAKRHRLESALTVGATELQRFRLHAPARTMPLMEPLRQAAEKLAQAQADLSRC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14052
Length:	648 (546)
Sequences:	1521 (1360)
Seq/√Len:	58.2

ECOLI - YEGI
BACSU - PRKC
HALSA - Q9HR00
SULSO - Q97U41 Q97U18 Q97WD5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
117_W	269_P	7.093	1.00
124_A	212_I	4.910	1.00
150_M	160_I	4.888	1.00
144_V	211_L	3.896	1.00
32_I	38_S	3.794	1.00
91_P	158_V	3.585	1.00
145_N	180_V	3.320	1.00
29_V	39_V	3.263	1.00
74_Q	91_P	3.225	1.00
32_I	40_A	3.170	1.00
19_R	31_D	3.150	1.00
274_A	278_Q	3.054	1.00
216_L	272_V	3.017	1.00
130_S	159_L	2.982	1.00
527_G	530_R	2.870	1.00
179_G	184_T	2.849	1.00
106_A	119_F	2.687	1.00
314_M	317_Y	2.668	1.00
516_F	520_V	2.493	1.00
210_L	222_P	2.384	1.00
283_S	288_G	2.346	1.00
120_L	216_L	2.337	1.00
398_E	402_S	2.301	1.00
462_Q	465_Q	2.213	1.00
324_C	327_C	2.208	1.00
25_G	199_R	2.202	1.00
370_Q	373_L	2.174	1.00
16_T	35_F	2.145	1.00
121_L	301_S	2.127	1.00
73_P	76_T	2.126	1.00
183_F	213_F	2.066	1.00
473_I	476_R	2.031	1.00
306_L	316_V	2.028	1.00
604_S	607_T	2.022	1.00
306_L	314_M	2.014	1.00
612_E	616_F	2.003	1.00
356_V	362_A	2.000	1.00
205_N	279_A	1.998	1.00
447_E	457_D	1.970	1.00
214_H	221_H	1.955	1.00
213_F	223_Y	1.947	1.00
361_M	364_V	1.943	1.00
319_A	322_T	1.914	1.00
276_F	280_F	1.897	1.00
404_L	407_L	1.888	1.00
589_Q	604_S	1.874	1.00
610_A	614_Q	1.857	1.00
470_E	474_A	1.831	1.00
66_L	72_W	1.815	0.99
400_A	405_S	1.814	0.99
445_R	457_D	1.807	0.99
360_V	365_A	1.807	0.99
322_T	325_P	1.806	0.99
511_K	514_E	1.805	0.99
206_F	210_L	1.800	0.99
359_M	364_V	1.795	0.99
281_T	288_G	1.758	0.99
380_T	383_P	1.750	0.99
366_P	373_L	1.743	0.99
445_R	448_A	1.740	0.99
283_S	287_T	1.732	0.99
402_S	406_L	1.721	0.99
379_P	382_R	1.714	0.99
446_R	459_L	1.712	0.99
611_T	616_F	1.705	0.99
400_A	404_L	1.700	0.99
368_A	377_F	1.693	0.99
564_V	568_K	1.688	0.99
491_E	498_A	1.688	0.99
609_G	614_Q	1.679	0.99
413_A	416_R	1.675	0.99
403_A	408_L	1.674	0.99
563_A	573_R	1.673	0.99
71_A	93_V	1.671	0.99
379_P	383_P	1.669	0.99
401_L	405_S	1.657	0.99
357_W	364_V	1.653	0.99
360_V	363_S	1.636	0.99
322_T	326_W	1.632	0.99
120_L	300_D	1.630	0.99
359_M	365_A	1.629	0.99
223_Y	226_V	1.627	0.99
487_L	495_R	1.622	0.99
558_D	568_K	1.620	0.99
374_P	379_P	1.610	0.99
566_D	576_V	1.607	0.99
397_L	400_A	1.600	0.99
568_K	573_R	1.597	0.99
356_V	359_M	1.592	0.99
378_Q	381_G	1.590	0.99
182_H	236_L	1.581	0.99
357_W	361_M	1.572	0.98
458_H	462_Q	1.564	0.98
611_T	615_R	1.562	0.98
360_V	364_V	1.558	0.98
454_M	464_Q	1.547	0.98
484_D	498_A	1.541	0.98
216_L	268_L	1.536	0.98
212_I	275_M	1.531	0.98
188_L	207_G	1.529	0.98
447_E	453_K	1.521	0.98
485_E	493_E	1.520	0.98
434_T	437_A	1.519	0.98
454_M	457_D	1.515	0.98
466_V	470_E	1.515	0.98
486_I	490_P	1.514	0.98
15_T	75_A	1.512	0.98
371_L	374_P	1.509	0.98
236_L	243_F	1.505	0.98
495_R	498_A	1.498	0.98
614_Q	617_R	1.494	0.98
152_G	156_K	1.486	0.98
366_P	370_Q	1.483	0.98
146_Q	211_L	1.479	0.98
174_H	177_E	1.476	0.98
185_P	203_H	1.472	0.98
430_I	434_T	1.469	0.98
565_I	574_R	1.466	0.98
132_A	136_E	1.463	0.98
279_A	295_W	1.462	0.98
487_L	496_A	1.452	0.97
399_I	409_C	1.451	0.97
143_D	163_D	1.432	0.97
585_P	589_Q	1.432	0.97
570_S	580_N	1.413	0.97
514_E	520_V	1.403	0.97
376_H	379_P	1.402	0.97
369_L	372_P	1.402	0.97
40_A	89_M	1.401	0.97
367_P	370_Q	1.392	0.97
429_I	433_L	1.384	0.97
45_T	78_H	1.379	0.96
399_I	406_L	1.379	0.96
185_P	228_L	1.376	0.96
22_G	29_V	1.376	0.96
67_L	133_T	1.368	0.96
364_V	370_Q	1.367	0.96
183_F	226_V	1.355	0.96
268_L	272_V	1.353	0.96
452_A	460_V	1.349	0.96
395_I	398_E	1.346	0.96
396_L	400_A	1.342	0.96
601_R	606_L	1.340	0.96
353_L	359_M	1.336	0.96
567_W	571_C	1.335	0.96
510_Q	514_E	1.333	0.96
205_N	292_A	1.326	0.96
188_L	199_R	1.324	0.96
357_W	362_A	1.322	0.95
323_D	326_W	1.320	0.95
428_W	434_T	1.312	0.95
358_A	361_M	1.310	0.95
356_V	364_V	1.307	0.95
429_I	432_S	1.305	0.95
400_A	413_A	1.300	0.95
404_L	408_L	1.295	0.95
320_H	325_P	1.290	0.95
431_G	435_S	1.281	0.95
178_V	199_R	1.281	0.95
555_G	568_K	1.279	0.95
598_K	611_T	1.272	0.94
350_N	353_L	1.271	0.94
533_A	536_S	1.267	0.94
513_L	518_I	1.267	0.94
53_D	165_F	1.267	0.94
274_A	298_A	1.267	0.94
358_A	362_A	1.263	0.94
463_I	467_G	1.261	0.94
614_Q	619_H	1.251	0.94
390_R	397_L	1.250	0.94
69_Y	152_G	1.248	0.94
528_P	533_A	1.245	0.94
361_M	365_A	1.244	0.94
526_V	530_R	1.242	0.94
529_A	533_A	1.241	0.94
349_G	356_V	1.241	0.94
396_L	408_L	1.240	0.94
208_L	211_L	1.240	0.94
524_P	527_G	1.240	0.94
31_D	37_D	1.239	0.94
146_Q	183_F	1.233	0.93
96_K	222_P	1.232	0.93
519_D	531_K	1.230	0.93
73_P	90_M	1.228	0.93
393_Y	396_L	1.227	0.93
278_Q	290_P	1.225	0.93
172_T	178_V	1.223	0.93
613_L	617_R	1.223	0.93
591_V	594_K	1.216	0.93
434_T	438_Y	1.214	0.93
558_D	566_D	1.210	0.93
593_A	596_T	1.209	0.93
370_Q	374_P	1.208	0.93
158_V	206_F	1.206	0.93
390_R	393_Y	1.206	0.93
521_A	530_R	1.205	0.93
577_F	588_R	1.205	0.93
553_V	556_F	1.202	0.93
172_T	177_E	1.198	0.92
525_G	534_L	1.196	0.92
173_L	177_E	1.194	0.92
611_T	618_L	1.191	0.92
377_F	384_L	1.188	0.92
609_G	618_L	1.180	0.92
206_F	222_P	1.180	0.92
604_S	609_G	1.177	0.92
392_E	404_L	1.176	0.92
557_G	561_T	1.172	0.92
164_S	182_H	1.167	0.91
217_F	296_V	1.161	0.91
124_A	208_L	1.159	0.91
357_W	360_V	1.159	0.91
126_N	156_K	1.159	0.91
370_Q	380_T	1.159	0.91
355_K	365_A	1.156	0.91
470_E	480_E	1.155	0.91
183_F	279_A	1.151	0.91
170_N	173_L	1.149	0.91
372_P	382_R	1.148	0.91
442_V	445_R	1.145	0.91
402_S	405_S	1.143	0.91
73_P	88_F	1.142	0.90
483_K	495_R	1.138	0.90
367_P	371_L	1.136	0.90
275_M	295_W	1.132	0.90
553_V	564_V	1.131	0.90
445_R	466_V	1.123	0.90
521_A	525_G	1.122	0.90
349_G	352_V	1.117	0.89
487_L	498_A	1.116	0.89
525_G	532_A	1.115	0.89
578_R	581_E	1.115	0.89
211_L	236_L	1.109	0.89
463_I	466_V	1.107	0.89
609_G	617_R	1.106	0.89
144_V	159_L	1.105	0.89
183_F	223_Y	1.101	0.89
595_M	599_R	1.098	0.89
573_R	580_N	1.097	0.89
213_F	236_L	1.096	0.89
457_D	463_I	1.095	0.89
408_L	412_Q	1.090	0.88
183_F	214_H	1.090	0.88
122_Y	126_N	1.087	0.88
531_K	535_R	1.086	0.88
453_K	464_Q	1.085	0.88
483_K	504_A	1.085	0.88
100_H	147_N	1.084	0.88
425_A	428_W	1.082	0.88
399_I	404_L	1.081	0.88
154_D	276_F	1.080	0.88
450_N	453_K	1.077	0.88
564_V	573_R	1.076	0.88
461_R	464_Q	1.076	0.88
614_Q	618_L	1.072	0.87
20_E	23_K	1.070	0.87
600_H	610_A	1.070	0.87
405_S	409_C	1.067	0.87
594_K	598_K	1.066	0.87
377_F	381_G	1.066	0.87
452_A	455_D	1.065	0.87
461_R	465_Q	1.065	0.87
494_K	498_A	1.060	0.87
444_Q	448_A	1.057	0.87
366_P	371_L	1.056	0.87
359_M	362_A	1.056	0.87
427_I	435_S	1.055	0.87
455_D	461_R	1.052	0.86
609_G	612_E	1.051	0.86
470_E	478_M	1.043	0.86
613_L	616_F	1.035	0.86
225_G	235_A	1.030	0.85
452_A	463_I	1.028	0.85
393_Y	397_L	1.027	0.85
373_L	376_H	1.023	0.85
352_V	356_V	1.020	0.85
368_A	371_L	1.019	0.85
372_P	376_H	1.017	0.85
147_N	164_S	1.014	0.84
443_Q	450_N	1.011	0.84
400_A	416_R	1.005	0.84
21_L	93_V	1.003	0.84
611_T	614_Q	1.000	0.84
607_T	617_R	1.000	0.84
585_P	598_K	0.997	0.83
545_V	548_R	0.996	0.83
178_V	215_V	0.996	0.83
538_G	542_A	0.995	0.83
128_A	296_V	0.995	0.83
538_G	544_D	0.994	0.83
441_E	447_E	0.993	0.83
442_V	462_Q	0.993	0.83
166_Q	236_L	0.993	0.83
507_R	510_Q	0.991	0.83
132_A	296_V	0.987	0.83
522_S	526_V	0.987	0.83
176_C	184_T	0.985	0.83
355_K	360_V	0.984	0.83
52_Q	150_M	0.984	0.83
243_F	282_E	0.980	0.82
357_W	363_S	0.979	0.82
183_F	211_L	0.978	0.82
166_Q	174_H	0.972	0.82
397_L	403_A	0.970	0.82
426_A	433_L	0.970	0.82
577_F	581_E	0.968	0.81
589_Q	603_E	0.965	0.81
37_D	59_A	0.964	0.81
557_G	560_L	0.963	0.81
402_S	408_L	0.961	0.81
476_R	479_L	0.960	0.81
323_D	327_C	0.958	0.81
451_R	458_H	0.957	0.81
374_P	377_F	0.955	0.81
90_M	97_E	0.952	0.80
326_W	330_D	0.950	0.80
210_L	247_Y	0.947	0.80
140_V	174_H	0.946	0.80
537_F	541_T	0.946	0.80
607_T	612_E	0.944	0.80
61_T	165_F	0.941	0.80
399_I	413_A	0.939	0.79
356_V	360_V	0.939	0.79
452_A	456_Y	0.938	0.79
399_I	402_S	0.936	0.79
616_F	619_H	0.934	0.79
236_L	245_Y	0.932	0.79
138_G	201_E	0.928	0.79
221_H	237_E	0.923	0.78
399_I	405_S	0.922	0.78
147_N	160_I	0.922	0.78
145_N	179_G	0.921	0.78
498_A	503_T	0.920	0.78
479_L	486_I	0.918	0.78
460_V	464_Q	0.917	0.78
494_K	497_L	0.916	0.78
574_R	578_R	0.915	0.78
228_L	236_L	0.915	0.78
320_H	326_W	0.914	0.78
502_D	506_E	0.914	0.78
588_R	591_V	0.914	0.78
410_G	422_P	0.913	0.77
347_T	351_F	0.909	0.77
546_T	549_G	0.908	0.77
369_L	381_G	0.908	0.77
351_F	358_A	0.907	0.77
523_I	526_V	0.907	0.77
583_I	586_A	0.906	0.77
400_A	407_L	0.906	0.77
62_A	221_H	0.905	0.77
327_C	330_D	0.905	0.77
127_I	130_S	0.902	0.77
511_K	515_G	0.900	0.76
450_N	464_Q	0.899	0.76
540_E	543_A	0.897	0.76
596_T	608_V	0.896	0.76
476_R	480_E	0.895	0.76
608_V	613_L	0.888	0.76
315_H	327_C	0.884	0.75
102_I	159_L	0.883	0.75
426_A	436_K	0.879	0.75
147_N	183_F	0.875	0.74
213_F	279_A	0.875	0.74
136_E	293_K	0.875	0.74
368_A	372_P	0.873	0.74
430_I	433_L	0.871	0.74
411_L	420_L	0.870	0.74
503_T	506_E	0.869	0.74
184_T	236_L	0.868	0.74
142_G	199_R	0.867	0.74
489_L	492_E	0.865	0.74
563_A	576_V	0.864	0.73
245_Y	248_A	0.862	0.73
356_V	363_S	0.862	0.73
601_R	612_E	0.861	0.73
369_L	375_D	0.861	0.73
391_R	394_I	0.860	0.73
368_A	376_H	0.859	0.73
426_A	430_I	0.858	0.73
598_K	606_L	0.858	0.73
152_G	157_V	0.857	0.73
31_D	295_W	0.856	0.73
609_G	613_L	0.853	0.73
26_E	164_S	0.853	0.73
128_A	295_W	0.852	0.72
594_K	597_A	0.851	0.72
393_Y	403_A	0.849	0.72
353_L	356_V	0.848	0.72
14_L	34_E	0.848	0.72
532_A	537_F	0.848	0.72
453_K	463_I	0.847	0.72
411_L	414_E	0.843	0.72
375_D	379_P	0.842	0.72
328_A	331_N	0.841	0.71
121_L	128_A	0.840	0.71
175_L	178_V	0.838	0.71
592_M	598_K	0.835	0.71
562_Q	566_D	0.835	0.71
390_R	405_S	0.835	0.71
321_L	324_C	0.834	0.71
554_K	570_S	0.834	0.71
397_L	404_L	0.833	0.71
574_R	579_P	0.832	0.71
393_Y	405_S	0.832	0.71
143_D	148_S	0.831	0.71
560_L	568_K	0.831	0.71
423_V	434_T	0.830	0.70
147_N	184_T	0.830	0.70
538_G	541_T	0.830	0.70
367_P	372_P	0.827	0.70
223_Y	279_A	0.826	0.70
182_H	214_H	0.826	0.70
140_V	221_H	0.826	0.70
539_I	543_A	0.825	0.70
409_C	415_P	0.824	0.70
453_K	460_V	0.824	0.70
62_A	182_H	0.823	0.70
174_H	184_T	0.822	0.70
479_L	483_K	0.822	0.70
143_D	161_D	0.821	0.70
522_S	530_R	0.820	0.70
450_N	454_M	0.815	0.69
605_A	617_R	0.813	0.69
570_S	573_R	0.812	0.69
445_R	459_L	0.809	0.68
597_A	602_L	0.809	0.68
43_Y	55_L	0.809	0.68
373_L	378_Q	0.809	0.68
527_G	531_K	0.808	0.68
187_E	286_A	0.808	0.68
39_V	298_A	0.808	0.68
356_V	361_M	0.807	0.68
372_P	380_T	0.805	0.68
403_A	409_C	0.805	0.68
206_F	209_A	0.804	0.68
164_S	211_L	0.804	0.68
469_L	477_T	0.803	0.68
322_T	328_A	0.802	0.68
407_L	416_R	0.802	0.68
184_T	282_E	0.801	0.68
147_N	181_S	0.800	0.68
52_Q	160_I	0.799	0.68
561_T	564_V	0.798	0.67
603_E	607_T	0.795	0.67
319_A	323_D	0.794	0.67
355_K	362_A	0.794	0.67
423_V	427_I	0.794	0.67
569_A	573_R	0.794	0.67
600_H	603_E	0.793	0.67
223_Y	236_L	0.792	0.67
478_M	481_K	0.791	0.67
526_V	529_A	0.791	0.67
568_K	580_N	0.784	0.66
576_V	580_N	0.783	0.66
373_L	377_F	0.783	0.66
206_F	223_Y	0.778	0.65
148_S	163_D	0.777	0.65
607_T	611_T	0.777	0.65
400_A	409_C	0.775	0.65
378_Q	382_R	0.774	0.65
573_R	577_F	0.773	0.65
189_Q	221_H	0.773	0.65
87_G	146_Q	0.773	0.65
607_T	618_L	0.772	0.65
146_Q	214_H	0.771	0.65
521_A	527_G	0.768	0.64
593_A	599_R	0.768	0.64
23_K	28_A	0.767	0.64
402_S	415_P	0.764	0.64
582_A	601_R	0.762	0.64
570_S	578_R	0.762	0.64
164_S	208_L	0.759	0.64
378_Q	383_P	0.759	0.64
450_N	456_Y	0.759	0.64
151_V	206_F	0.759	0.64
181_S	184_T	0.759	0.64
425_A	432_S	0.758	0.63
184_T	228_L	0.757	0.63
54_K	146_Q	0.757	0.63
399_I	410_G	0.756	0.63
315_H	320_H	0.756	0.63
360_V	378_Q	0.755	0.63
562_Q	584_T	0.754	0.63
236_L	248_A	0.753	0.63
615_R	618_L	0.751	0.63
179_G	213_F	0.751	0.63
459_L	466_V	0.750	0.63
595_M	606_L	0.750	0.63
482_M	486_I	0.750	0.63
179_G	222_P	0.749	0.63
604_S	619_H	0.747	0.62
321_L	325_P	0.747	0.62
589_Q	599_R	0.747	0.62
446_R	455_D	0.746	0.62
184_T	224_S	0.745	0.62
392_E	396_L	0.744	0.62
164_S	228_L	0.743	0.62
457_D	464_Q	0.742	0.62
561_T	566_D	0.742	0.62
322_T	327_C	0.740	0.62
491_E	496_A	0.740	0.62
392_E	395_I	0.740	0.62
453_K	461_R	0.739	0.61
397_L	402_S	0.739	0.61
372_P	383_P	0.737	0.61
606_L	610_A	0.737	0.61
318_P	322_T	0.736	0.61
370_Q	377_F	0.735	0.61
367_P	373_L	0.734	0.61
487_L	491_E	0.733	0.61
130_S	156_K	0.732	0.61
561_T	565_I	0.732	0.61
396_L	402_S	0.732	0.61
492_E	495_R	0.731	0.61
601_R	610_A	0.731	0.61
532_A	543_A	0.727	0.60
147_N	182_H	0.727	0.60
579_P	592_M	0.726	0.60
147_N	301_S	0.725	0.60
55_L	189_Q	0.725	0.60
575_F	579_P	0.724	0.60
162_S	206_F	0.723	0.60
402_S	413_A	0.722	0.60
453_K	457_D	0.719	0.59
603_E	609_G	0.719	0.59
124_A	300_D	0.718	0.59
471_G	475_K	0.718	0.59
348_G	351_F	0.717	0.59
410_G	413_A	0.717	0.59
400_A	406_L	0.716	0.59
569_A	577_F	0.716	0.59
494_K	504_A	0.714	0.59
124_A	275_M	0.714	0.59
394_I	403_A	0.712	0.59
613_L	619_H	0.711	0.58
356_V	365_A	0.711	0.58
21_L	33_E	0.711	0.58
575_F	586_A	0.710	0.58
199_R	239_D	0.709	0.58
474_A	477_T	0.709	0.58
530_R	535_R	0.709	0.58
539_I	542_A	0.708	0.58
597_A	612_E	0.708	0.58
546_T	550_V	0.707	0.58
446_R	450_N	0.707	0.58
450_N	468_G	0.707	0.58
93_V	160_I	0.705	0.58
401_L	407_L	0.705	0.58
395_I	410_G	0.703	0.58
362_A	365_A	0.701	0.57
16_T	33_E	0.701	0.57
38_S	89_M	0.699	0.57
600_H	609_G	0.697	0.57
615_R	619_H	0.697	0.57
407_L	419_I	0.697	0.57
207_G	214_H	0.695	0.57
447_E	468_G	0.695	0.57
567_W	578_R	0.695	0.57
391_R	403_A	0.695	0.57
93_V	208_L	0.694	0.57
395_I	405_S	0.694	0.57
178_V	214_H	0.694	0.57
120_L	290_P	0.693	0.57
601_R	608_V	0.693	0.57
448_A	452_A	0.693	0.57
28_A	31_D	0.689	0.56
374_P	382_R	0.689	0.56
406_L	413_A	0.688	0.56
368_A	374_P	0.688	0.56
216_L	300_D	0.687	0.56
363_S	373_L	0.687	0.56
292_A	295_W	0.685	0.56
347_T	360_V	0.685	0.56
403_A	415_P	0.684	0.56
354_A	357_W	0.682	0.55
394_I	404_L	0.680	0.55
600_H	607_T	0.678	0.55
483_K	486_I	0.678	0.55
529_A	549_G	0.678	0.55
460_V	468_G	0.675	0.55
350_N	357_W	0.674	0.54
146_Q	182_H	0.674	0.54
586_A	589_Q	0.673	0.54
347_T	350_N	0.673	0.54
148_S	161_D	0.673	0.54
400_A	408_L	0.671	0.54
472_F	480_E	0.670	0.54
490_P	498_A	0.669	0.54
15_T	77_L	0.666	0.54
380_T	384_L	0.666	0.54
115_C	210_L	0.663	0.53
604_S	611_T	0.662	0.53
419_I	431_G	0.661	0.53
369_L	376_H	0.658	0.53
444_Q	457_D	0.658	0.53
366_P	375_D	0.658	0.53
373_L	381_G	0.658	0.53
603_E	606_L	0.656	0.52
488_G	496_A	0.655	0.52
441_E	453_K	0.654	0.52
580_N	588_R	0.654	0.52
184_T	213_F	0.654	0.52
568_K	588_R	0.653	0.52
96_K	179_G	0.653	0.52
320_H	323_D	0.653	0.52
182_H	206_F	0.652	0.52
17_L	32_I	0.651	0.52
595_M	603_E	0.651	0.52
532_A	541_T	0.649	0.52
524_P	532_A	0.649	0.52
589_Q	593_A	0.647	0.51
496_A	506_E	0.647	0.51
507_R	511_K	0.647	0.51
123_V	157_V	0.647	0.51
351_F	356_V	0.646	0.51
199_R	207_G	0.646	0.51
377_F	380_T	0.645	0.51
476_R	493_E	0.644	0.51
428_W	431_G	0.644	0.51
475_K	479_L	0.644	0.51
521_A	524_P	0.643	0.51
501_H	515_G	0.642	0.51
599_R	603_E	0.642	0.51
601_R	605_A	0.639	0.51
566_D	569_A	0.639	0.51
320_H	329_L	0.639	0.51
355_K	359_M	0.638	0.50
522_S	527_G	0.638	0.50
96_K	181_S	0.637	0.50
410_G	416_R	0.635	0.50
604_S	608_V	0.634	0.50
427_I	430_I	0.633	0.50
327_C	331_N	0.632	0.50
87_G	123_V	0.632	0.50
166_Q	225_G	0.632	0.50
554_K	573_R	0.631	0.50
127_I	149_F	0.629	0.50
504_A	507_R	0.629	0.50
180_V	290_P	0.628	0.49
503_T	507_R	0.628	0.49
494_K	502_D	0.627	0.49
440_A	445_R	0.626	0.49
369_L	373_L	0.626	0.49
186_P	289_R	0.626	0.49
62_A	172_T	0.624	0.49
411_L	417_Y	0.622	0.49
539_I	544_D	0.621	0.49
100_H	178_V	0.621	0.49
182_H	221_H	0.621	0.49
213_F	245_Y	0.621	0.49
506_E	509_K	0.619	0.48
90_M	95_G	0.618	0.48
146_Q	290_P	0.618	0.48
134_V	279_A	0.616	0.48
411_L	415_P	0.616	0.48
353_L	357_W	0.616	0.48
93_V	217_F	0.616	0.48
560_L	563_A	0.615	0.48
404_L	409_C	0.613	0.48
206_F	214_H	0.613	0.48
603_E	618_L	0.613	0.48
210_L	223_Y	0.612	0.48
397_L	401_L	0.612	0.48
578_R	585_P	0.611	0.48
578_R	582_A	0.609	0.47
592_M	603_E	0.609	0.47
581_E	585_P	0.608	0.47
593_A	598_K	0.604	0.47
590_A	597_A	0.603	0.47
176_C	181_S	0.602	0.47
365_A	368_A	0.602	0.47
596_T	607_T	0.602	0.47
558_D	561_T	0.601	0.46
586_A	590_A	0.601	0.46
217_F	221_H	0.600	0.46
532_A	535_R	0.598	0.46
428_W	432_S	0.597	0.46
177_E	211_L	0.597	0.46
392_E	407_L	0.596	0.46
422_P	426_A	0.595	0.46
482_M	493_E	0.594	0.46
457_D	471_G	0.593	0.46
507_R	512_F	0.592	0.45
408_L	429_I	0.591	0.45
320_H	327_C	0.590	0.45
442_V	459_L	0.590	0.45
349_G	354_A	0.590	0.45
542_A	545_V	0.589	0.45
78_H	87_G	0.589	0.45
51_K	62_A	0.589	0.45
392_E	398_E	0.588	0.45
407_L	410_G	0.588	0.45
179_G	182_H	0.588	0.45
446_R	452_A	0.588	0.45
315_H	323_D	0.586	0.45
370_Q	379_P	0.586	0.45
225_G	228_L	0.586	0.45
601_R	609_G	0.585	0.45
365_A	378_Q	0.584	0.45
223_Y	243_F	0.584	0.45
588_R	606_L	0.584	0.45
121_L	216_L	0.583	0.44
535_R	539_I	0.580	0.44
404_L	414_E	0.580	0.44
584_T	605_A	0.580	0.44
476_R	485_E	0.579	0.44
351_F	360_V	0.576	0.44
482_M	507_R	0.576	0.44
582_A	590_A	0.576	0.44
97_E	160_I	0.574	0.43
368_A	378_Q	0.572	0.43
383_P	386_L	0.572	0.43
398_E	405_S	0.571	0.43
424_L	434_T	0.571	0.43
400_A	403_A	0.569	0.43
556_F	570_S	0.569	0.43
541_T	547_R	0.569	0.43
596_T	606_L	0.569	0.43
206_F	240_I	0.568	0.43
395_I	399_I	0.568	0.43
465_Q	495_R	0.568	0.43
461_R	466_V	0.567	0.43
609_G	616_F	0.566	0.43
54_K	61_T	0.566	0.43
27_G	31_D	0.565	0.42
347_T	353_L	0.563	0.42
460_V	463_I	0.562	0.42
572_E	586_A	0.562	0.42
480_E	484_D	0.562	0.42
13_E	16_T	0.562	0.42
41_K	58_M	0.562	0.42
365_A	372_P	0.559	0.42
448_A	454_M	0.558	0.42
40_A	57_F	0.554	0.41
485_E	519_D	0.554	0.41
562_Q	575_F	0.553	0.41
509_K	516_F	0.553	0.41
397_L	412_Q	0.551	0.41
15_T	26_E	0.551	0.41
427_I	432_S	0.550	0.41
525_G	533_A	0.548	0.41
488_G	499_A	0.547	0.41
217_F	223_Y	0.547	0.41
451_R	463_I	0.544	0.40
184_T	214_H	0.543	0.40
396_L	410_G	0.540	0.40
62_A	86_I	0.540	0.40
319_A	325_P	0.539	0.40
465_Q	469_L	0.539	0.40
25_G	51_K	0.538	0.40
395_I	401_L	0.537	0.39
394_I	398_E	0.537	0.39
606_L	614_Q	0.537	0.39
593_A	607_T	0.536	0.39
325_P	328_A	0.536	0.39
509_K	518_I	0.535	0.39
421_V	432_S	0.534	0.39
587_D	595_M	0.534	0.39
576_V	584_T	0.533	0.39
329_L	332_Q	0.533	0.39
580_N	584_T	0.532	0.39
447_E	469_L	0.532	0.39
541_T	548_R	0.531	0.39
560_L	578_R	0.529	0.39
395_I	407_L	0.528	0.39
97_E	147_N	0.527	0.38
606_L	609_G	0.527	0.38
443_Q	459_L	0.526	0.38
577_F	606_L	0.524	0.38
498_A	501_H	0.524	0.38
121_L	300_D	0.523	0.38
24_G	27_G	0.522	0.38
521_A	531_K	0.522	0.38
228_L	243_F	0.522	0.38
581_E	595_M	0.522	0.38
55_L	59_A	0.521	0.38
124_A	134_V	0.521	0.38
525_G	528_P	0.520	0.38
596_T	599_R	0.520	0.38
553_V	581_E	0.520	0.38
213_F	222_P	0.519	0.38
176_C	182_H	0.517	0.37
450_N	459_L	0.516	0.37
559_H	563_A	0.516	0.37
22_G	25_G	0.516	0.37
488_G	491_E	0.515	0.37
581_E	591_V	0.515	0.37
445_R	454_M	0.514	0.37
610_A	616_F	0.512	0.37
146_Q	160_I	0.512	0.37
86_I	199_R	0.512	0.37
424_L	431_G	0.512	0.37
553_V	557_G	0.511	0.37
397_L	413_A	0.511	0.37
449_F	457_D	0.510	0.37
572_E	579_P	0.510	0.37
600_H	604_S	0.509	0.37
315_H	319_A	0.507	0.36
582_A	585_P	0.507	0.36
54_K	88_F	0.507	0.36
570_S	591_V	0.506	0.36
509_K	513_L	0.506	0.36
40_A	87_G	0.506	0.36
87_G	188_L	0.506	0.36
480_E	483_K	0.505	0.36
424_L	430_I	0.505	0.36
557_G	573_R	0.504	0.36
469_L	472_F	0.503	0.36
497_L	517_F	0.503	0.36
575_F	590_A	0.503	0.36
326_W	331_N	0.503	0.36
490_P	503_T	0.502	0.36
611_T	619_H	0.501	0.36
577_F	591_V	0.501	0.36
164_S	178_V	0.501	0.36
402_S	409_C	0.500	0.36
557_G	562_Q	0.500	0.36
607_T	610_A	0.500	0.36
86_I	129_S	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4lqsA	1	0.4568	100	0.427	Contact Map
4ejnA	1	0.4012	100	0.438	Contact Map
4gv1A	1	0.4815	100	0.439	Contact Map
4aw2A	2	0.4969	100	0.444	Contact Map
3pfqA	1	0.4846	100	0.444	Contact Map
2yabA	2	0.4429	100	0.447	Contact Map
4dc2A	1	0.4799	100	0.448	Contact Map
2bdwA	2	0.466	100	0.451	Contact Map
4ic7A	1	0.5062	100	0.451	Contact Map
3v8sA	2	0.4985	100	0.451	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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