YEGH - ECOLI - GREMLIN Contacts

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YEGH - UPF0053 protein YegH

UniProt:	P76389	Sequences: MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRDRARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKATMELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAAVVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVDHGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHTRLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFRNARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHRVQKVQIIPLRKDGEMEYEV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14051
Length:	527 (423)
Sequences:	1385 (876)
Seq/√Len:	42.6

ECOLI - YEGH YOAE YTFL YFJD
BACSU - YHDP YHDT YUGS YRKA YQHB
HALSA - Q9HHN9 Q9HN02

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
106_N	110_E	4.449	1.00
378_F	387_A	4.142	1.00
484_R	490_E	3.928	1.00
106_N	109_L	3.824	1.00
105_L	109_L	3.672	1.00
103_M	109_L	3.293	1.00
103_M	110_E	3.218	1.00
478_L	512_V	3.152	1.00
312_I	411_I	3.151	1.00
491_E	500_K	3.116	1.00
105_L	110_E	3.097	1.00
99_F	102_T	3.097	1.00
102_T	109_L	3.011	1.00
109_L	112_K	2.974	1.00
103_M	106_N	2.881	1.00
340_D	346_D	2.872	1.00
105_L	108_R	2.870	1.00
102_T	106_N	2.794	1.00
319_A	323_E	2.741	1.00
493_Q	498_L	2.721	1.00
102_T	110_E	2.686	1.00
447_T	502_L	2.663	1.00
120_R	134_V	2.654	1.00
500_K	515_I	2.628	1.00
320_P	323_E	2.625	1.00
448_A	514_I	2.568	1.00
102_T	105_L	2.508	1.00
106_N	112_K	2.479	1.00
491_E	498_L	2.452	1.00
104_E	110_E	2.440	1.00
98_L	102_T	2.431	1.00
108_R	111_G	2.408	1.00
302_V	387_A	2.354	1.00
106_N	111_G	2.342	1.00
99_F	109_L	2.295	1.00
498_L	515_I	2.273	1.00
99_F	103_M	2.270	1.00
447_T	511_K	2.256	1.00
103_M	112_K	2.249	1.00
108_R	112_K	2.231	1.00
314_H	339_T	2.216	1.00
109_L	114_S	2.168	1.00
99_F	110_E	2.142	0.99
102_T	108_R	2.139	0.99
103_M	108_R	2.120	0.99
109_L	113_D	2.112	0.99
387_A	412_V	2.103	0.99
105_L	113_D	2.085	0.99
200_L	249_T	2.066	0.99
104_E	109_L	2.050	0.99
101_A	108_R	2.038	0.99
505_E	510_Q	2.016	0.99
111_G	114_S	2.004	0.99
110_E	113_D	1.996	0.99
101_A	105_L	1.990	0.99
339_T	347_L	1.989	0.99
110_E	114_S	1.962	0.99
103_M	111_G	1.926	0.99
104_E	108_R	1.904	0.99
98_L	105_L	1.888	0.99
315_I	324_I	1.883	0.99
104_E	112_K	1.856	0.99
305_I	384_L	1.856	0.99
98_L	109_L	1.847	0.98
124_K	127_G	1.827	0.98
157_M	160_A	1.818	0.98
99_F	106_N	1.796	0.98
106_N	113_D	1.787	0.98
105_L	111_G	1.785	0.98
355_D	373_R	1.773	0.98
474_I	512_V	1.751	0.98
94_G	98_L	1.726	0.98
102_T	114_S	1.719	0.98
477_L	494_V	1.707	0.97
442_A	445_S	1.695	0.97
98_L	103_M	1.675	0.97
101_A	110_E	1.667	0.97
102_T	113_D	1.648	0.97
382_L	390_Q	1.640	0.97
503_Q	510_Q	1.628	0.97
156_V	202_A	1.616	0.96
186_V	189_C	1.592	0.96
108_R	113_D	1.581	0.96
100_K	103_M	1.572	0.96
102_T	111_G	1.550	0.95
218_I	221_S	1.544	0.95
350_V	398_F	1.537	0.95
448_A	457_L	1.534	0.95
128_V	131_Q	1.534	0.95
419_E	428_E	1.530	0.95
159_A	202_A	1.529	0.95
479_M	509_V	1.515	0.95
109_L	115_N	1.514	0.95
99_F	105_L	1.506	0.95
290_M	421_I	1.503	0.95
102_T	112_K	1.490	0.94
99_F	104_E	1.476	0.94
457_L	461_V	1.452	0.94
107_E	110_E	1.451	0.93
106_N	114_S	1.451	0.93
326_Q	330_R	1.433	0.93
105_L	112_K	1.427	0.93
99_F	114_S	1.424	0.93
110_E	115_N	1.415	0.93
345_E	407_S	1.400	0.92
351_V	372_I	1.394	0.92
242_N	246_R	1.375	0.91
338_V	372_I	1.368	0.91
185_I	189_C	1.359	0.91
99_F	108_R	1.344	0.91
101_A	109_L	1.343	0.91
384_L	417_V	1.328	0.90
98_L	110_E	1.319	0.90
457_L	514_I	1.317	0.90
347_L	400_F	1.309	0.89
98_L	111_G	1.309	0.89
478_L	501_T	1.305	0.89
317_L	372_I	1.303	0.89
100_K	110_E	1.291	0.89
104_E	229_Q	1.290	0.89
315_I	368_L	1.263	0.88
502_L	513_Q	1.260	0.87
127_G	131_Q	1.252	0.87
157_M	199_S	1.252	0.87
120_R	124_K	1.241	0.87
340_D	369_R	1.238	0.87
102_T	156_V	1.236	0.86
101_A	104_E	1.235	0.86
422_A	425_L	1.216	0.85
100_K	104_E	1.212	0.85
312_I	408_V	1.211	0.85
398_F	411_I	1.209	0.85
98_L	101_A	1.202	0.85
157_M	195_M	1.196	0.85
463_L	497_Y	1.187	0.84
149_G	153_H	1.183	0.84
415_S	428_E	1.181	0.84
105_L	114_S	1.180	0.84
146_T	160_A	1.176	0.84
160_A	163_I	1.174	0.83
103_M	114_S	1.173	0.83
496_D	517_L	1.172	0.83
478_L	499_L	1.162	0.83
151_V	160_A	1.156	0.82
499_L	514_I	1.155	0.82
163_I	198_F	1.155	0.82
160_A	199_S	1.150	0.82
145_I	153_H	1.135	0.81
95_F	98_L	1.134	0.81
96_F	100_K	1.133	0.81
441_N	445_S	1.132	0.81
142_D	212_G	1.125	0.81
106_N	115_N	1.117	0.80
335_R	415_S	1.115	0.80
101_A	106_N	1.110	0.80
119_Q	122_G	1.109	0.80
98_L	108_R	1.108	0.80
104_E	111_G	1.099	0.79
494_V	499_L	1.093	0.79
403_D	406_G	1.093	0.79
149_G	160_A	1.087	0.78
100_K	106_N	1.085	0.78
141_L	144_V	1.083	0.78
351_V	388_L	1.081	0.78
112_K	115_N	1.075	0.78
99_F	112_K	1.073	0.77
252_A	256_L	1.073	0.77
312_I	344_A	1.073	0.77
149_G	152_D	1.061	0.77
164_A	194_L	1.057	0.76
157_M	164_A	1.057	0.76
160_A	164_A	1.054	0.76
369_R	372_I	1.053	0.76
146_T	153_H	1.052	0.76
441_N	503_Q	1.052	0.76
337_V	400_F	1.047	0.76
120_R	127_G	1.047	0.76
99_F	111_G	1.046	0.76
103_M	113_D	1.045	0.76
157_M	165_I	1.040	0.75
145_I	152_D	1.039	0.75
184_T	188_L	1.035	0.75
123_A	224_I	1.033	0.75
500_K	513_Q	1.031	0.75
148_V	161_V	1.025	0.74
441_N	444_G	1.024	0.74
156_V	195_M	1.020	0.74
105_L	115_N	1.020	0.74
93_G	100_K	1.017	0.74
91_L	95_F	1.007	0.73
447_T	513_Q	1.006	0.73
152_D	208_V	1.001	0.72
103_M	107_E	0.994	0.72
382_L	387_A	0.992	0.72
294_V	421_I	0.990	0.71
348_L	372_I	0.990	0.71
225_E	229_Q	0.990	0.71
497_Y	514_I	0.985	0.71
101_A	112_K	0.984	0.71
319_A	496_D	0.983	0.71
335_R	397_H	0.982	0.71
314_H	344_A	0.977	0.70
498_L	517_L	0.973	0.70
142_D	146_T	0.973	0.70
313_E	333_H	0.970	0.70
405_F	450_G	0.970	0.70
239_L	243_Q	0.966	0.70
108_R	114_S	0.964	0.69
355_D	429_V	0.963	0.69
475_A	508_R	0.959	0.69
208_V	223_M	0.958	0.69
317_L	340_D	0.952	0.68
475_A	479_M	0.949	0.68
415_S	427_N	0.947	0.68
130_T	228_N	0.944	0.68
187_I	190_L	0.939	0.67
426_P	430_E	0.937	0.67
112_K	116_N	0.936	0.67
336_L	353_V	0.935	0.67
160_A	195_M	0.934	0.67
415_S	419_E	0.928	0.66
409_E	420_T	0.928	0.66
448_A	460_Y	0.927	0.66
351_V	371_L	0.925	0.66
445_S	513_Q	0.924	0.66
150_M	157_M	0.924	0.66
116_N	119_Q	0.923	0.66
439_Q	447_T	0.923	0.66
146_T	149_G	0.921	0.66
205_F	514_I	0.919	0.66
152_D	207_F	0.916	0.65
338_V	368_L	0.916	0.65
247_Q	250_T	0.911	0.65
415_S	425_L	0.911	0.65
499_L	512_V	0.909	0.65
118_T	121_K	0.908	0.65
244_T	248_R	0.906	0.65
160_A	194_L	0.905	0.64
141_L	212_G	0.905	0.64
323_E	326_Q	0.903	0.64
158_M	161_V	0.903	0.64
405_F	492_V	0.900	0.64
205_F	516_P	0.898	0.64
389_E	392_R	0.897	0.64
415_S	420_T	0.897	0.64
98_L	114_S	0.897	0.64
419_E	430_E	0.896	0.64
164_A	199_S	0.896	0.64
119_Q	123_A	0.893	0.63
277_H	283_F	0.890	0.63
98_L	113_D	0.890	0.63
380_E	409_E	0.886	0.63
160_A	203_E	0.883	0.63
131_Q	153_H	0.881	0.62
91_L	94_G	0.881	0.62
113_D	116_N	0.880	0.62
334_T	514_I	0.878	0.62
441_N	447_T	0.878	0.62
95_F	99_F	0.878	0.62
141_L	155_L	0.876	0.62
145_I	149_G	0.874	0.62
427_N	430_E	0.869	0.61
400_F	411_I	0.868	0.61
148_V	212_G	0.864	0.61
441_N	513_Q	0.863	0.61
441_N	510_Q	0.863	0.61
110_E	116_N	0.860	0.61
164_A	203_E	0.859	0.60
454_L	500_K	0.855	0.60
144_V	148_V	0.855	0.60
226_A	233_F	0.854	0.60
400_F	408_V	0.853	0.60
103_M	115_N	0.852	0.60
310_H	407_S	0.850	0.60
98_L	106_N	0.850	0.60
342_D	371_L	0.849	0.60
195_M	202_A	0.846	0.59
466_D	471_Y	0.841	0.59
150_M	165_I	0.838	0.58
354_I	387_A	0.834	0.58
355_D	395_R	0.834	0.58
104_E	107_E	0.834	0.58
266_L	269_E	0.834	0.58
228_N	232_I	0.833	0.58
277_H	281_Q	0.830	0.58
144_V	230_L	0.827	0.57
321_E	371_L	0.826	0.57
317_L	348_L	0.826	0.57
482_L	492_V	0.824	0.57
344_A	408_V	0.822	0.57
313_E	336_L	0.819	0.57
248_R	251_E	0.819	0.57
319_A	324_I	0.817	0.57
425_L	429_V	0.817	0.57
445_S	500_K	0.816	0.56
109_L	116_N	0.816	0.56
158_M	202_A	0.813	0.56
107_E	111_G	0.809	0.56
309_R	345_E	0.808	0.56
274_L	297_L	0.807	0.56
415_S	422_A	0.807	0.56
359_Q	366_L	0.807	0.56
454_L	457_L	0.804	0.55
353_V	412_V	0.802	0.55
91_L	98_L	0.800	0.55
379_P	404_E	0.798	0.55
143_S	234_N	0.796	0.55
153_H	160_A	0.795	0.54
120_R	135_L	0.794	0.54
241_A	245_L	0.793	0.54
452_M	474_I	0.791	0.54
325_R	478_L	0.791	0.54
129_V	136_D	0.791	0.54
167_L	307_T	0.790	0.54
335_R	352_H	0.786	0.54
146_T	152_D	0.786	0.54
438_I	452_M	0.783	0.53
493_Q	496_D	0.782	0.53
331_N	336_L	0.782	0.53
270_T	277_H	0.782	0.53
209_I	307_T	0.775	0.53
153_H	207_F	0.775	0.53
129_V	196_I	0.774	0.53
102_T	115_N	0.773	0.52
404_E	473_T	0.771	0.52
270_T	273_M	0.770	0.52
101_A	113_D	0.767	0.52
211_K	214_L	0.766	0.52
177_Q	323_E	0.759	0.51
474_I	511_K	0.758	0.51
384_L	420_T	0.757	0.51
302_V	378_F	0.755	0.51
146_T	151_V	0.754	0.51
438_I	513_Q	0.753	0.51
359_Q	371_L	0.750	0.50
352_H	355_D	0.748	0.50
145_I	151_V	0.747	0.50
431_E	490_E	0.745	0.50
99_F	113_D	0.745	0.50
309_R	406_G	0.744	0.50
128_V	224_I	0.744	0.50
452_M	457_L	0.741	0.49
299_Q	449_N	0.741	0.49
510_Q	513_Q	0.740	0.49
141_L	233_F	0.740	0.49
367_N	370_V	0.740	0.49
369_R	381_T	0.736	0.49
100_K	109_L	0.736	0.49
487_K	490_E	0.733	0.49
352_H	429_V	0.733	0.49
101_A	111_G	0.731	0.48
379_P	382_L	0.731	0.48
131_Q	149_G	0.731	0.48
322_E	500_K	0.730	0.48
324_I	327_L	0.728	0.48
209_I	257_L	0.728	0.48
150_M	164_A	0.728	0.48
492_V	499_L	0.726	0.48
160_A	165_I	0.726	0.48
415_S	429_V	0.724	0.48
357_L	388_L	0.723	0.48
97_L	100_K	0.723	0.48
121_K	127_G	0.723	0.48
203_E	212_G	0.723	0.48
125_F	190_L	0.720	0.47
157_M	215_Y	0.719	0.47
143_S	147_A	0.718	0.47
309_R	403_D	0.717	0.47
378_F	401_V	0.715	0.47
195_M	203_E	0.710	0.46
255_R	261_K	0.710	0.46
145_I	207_F	0.709	0.46
238_F	244_T	0.708	0.46
440_K	446_W	0.706	0.46
419_E	427_N	0.706	0.46
287_E	294_V	0.703	0.46
491_E	501_T	0.703	0.46
398_F	408_V	0.702	0.46
316_D	342_D	0.698	0.45
193_L	249_T	0.697	0.45
150_M	233_F	0.696	0.45
161_V	203_E	0.696	0.45
153_H	208_V	0.696	0.45
181_S	185_I	0.695	0.45
151_V	199_S	0.692	0.45
335_R	428_E	0.691	0.45
291_I	358_Q	0.691	0.45
165_I	199_S	0.689	0.44
386_P	390_Q	0.688	0.44
309_R	404_E	0.688	0.44
228_N	231_A	0.688	0.44
337_V	354_I	0.687	0.44
351_V	462_P	0.687	0.44
496_D	516_P	0.686	0.44
375_P	402_V	0.686	0.44
141_L	148_V	0.686	0.44
297_L	385_L	0.685	0.44
441_N	500_K	0.685	0.44
148_V	157_M	0.683	0.44
156_V	163_I	0.683	0.44
378_F	412_V	0.683	0.44
121_K	135_L	0.681	0.44
335_R	430_E	0.681	0.44
415_S	430_E	0.680	0.44
197_G	512_V	0.679	0.44
403_D	412_V	0.679	0.44
344_A	446_W	0.679	0.44
192_F	205_F	0.679	0.44
347_L	512_V	0.678	0.43
144_V	163_I	0.676	0.43
396_T	457_L	0.674	0.43
129_V	132_I	0.673	0.43
386_P	466_D	0.670	0.43
337_V	427_N	0.669	0.43
306_M	421_I	0.669	0.43
133_V	231_A	0.669	0.43
232_I	346_D	0.667	0.42
128_V	446_W	0.667	0.42
159_A	163_I	0.659	0.42
251_E	255_R	0.657	0.42
345_E	380_E	0.656	0.41
301_T	348_L	0.656	0.41
392_R	466_D	0.655	0.41
99_F	115_N	0.654	0.41
152_D	160_A	0.652	0.41
209_I	253_V	0.652	0.41
300_R	304_S	0.647	0.41
141_L	162_V	0.646	0.41
221_S	225_E	0.646	0.41
129_V	520_D	0.645	0.40
102_T	107_E	0.644	0.40
184_T	189_C	0.644	0.40
151_V	163_I	0.641	0.40
240_S	244_T	0.640	0.40
450_G	474_I	0.640	0.40
198_F	506_S	0.639	0.40
457_L	474_I	0.638	0.40
469_R	472_H	0.638	0.40
350_V	375_P	0.637	0.40
159_A	198_F	0.636	0.40
131_Q	220_F	0.635	0.40
347_L	475_A	0.634	0.39
465_L	497_Y	0.634	0.39
407_S	420_T	0.634	0.39
144_V	233_F	0.634	0.39
345_E	475_A	0.633	0.39
347_L	387_A	0.631	0.39
134_V	137_A	0.629	0.39
347_L	377_V	0.629	0.39
352_H	397_H	0.628	0.39
137_A	144_V	0.628	0.39
194_L	203_E	0.627	0.39
322_E	519_K	0.625	0.39
274_L	352_H	0.624	0.39
287_E	418_T	0.624	0.39
488_P	503_Q	0.622	0.38
101_A	107_E	0.620	0.38
364_E	367_N	0.620	0.38
238_F	241_A	0.619	0.38
171_A	213_Y	0.618	0.38
317_L	369_R	0.618	0.38
164_A	195_M	0.615	0.38
156_V	160_A	0.615	0.38
106_N	116_N	0.615	0.38
485_I	504_V	0.614	0.38
91_L	97_L	0.614	0.38
478_L	482_L	0.613	0.38
121_K	124_K	0.613	0.38
148_V	155_L	0.613	0.38
135_L	139_F	0.612	0.37
205_F	222_V	0.611	0.37
299_Q	459_Q	0.610	0.37
95_F	102_T	0.608	0.37
337_V	353_V	0.608	0.37
108_R	116_N	0.606	0.37
96_F	103_M	0.606	0.37
184_T	187_I	0.606	0.37
241_A	269_E	0.605	0.37
124_K	131_Q	0.605	0.37
397_H	415_S	0.603	0.37
184_T	196_I	0.602	0.37
151_V	207_F	0.602	0.37
290_M	294_V	0.602	0.37
165_I	194_L	0.600	0.36
356_L	359_Q	0.599	0.36
132_I	136_D	0.598	0.36
96_F	104_E	0.597	0.36
415_S	472_H	0.596	0.36
149_G	208_V	0.596	0.36
510_Q	515_I	0.596	0.36
92_F	95_F	0.595	0.36
167_L	310_H	0.594	0.36
170_M	250_T	0.593	0.36
424_N	428_E	0.590	0.36
132_I	186_V	0.590	0.36
296_N	459_Q	0.590	0.36
157_M	202_A	0.587	0.35
95_F	167_L	0.587	0.35
384_L	456_D	0.587	0.35
157_M	203_E	0.583	0.35
144_V	212_G	0.583	0.35
291_I	355_D	0.583	0.35
305_I	412_V	0.582	0.35
196_I	297_L	0.579	0.35
332_Q	381_T	0.579	0.35
461_V	499_L	0.577	0.34
146_T	156_V	0.576	0.34
151_V	157_M	0.576	0.34
278_G	288_R	0.576	0.34
339_T	344_A	0.575	0.34
135_L	474_I	0.575	0.34
142_D	250_T	0.574	0.34
227_L	231_A	0.572	0.34
180_N	185_I	0.572	0.34
111_G	116_N	0.571	0.34
91_L	99_F	0.571	0.34
161_V	170_M	0.571	0.34
338_V	412_V	0.570	0.34
162_V	203_E	0.570	0.34
111_G	115_N	0.570	0.34
455_E	466_D	0.569	0.34
418_T	422_A	0.569	0.34
238_F	242_N	0.569	0.34
99_F	107_E	0.569	0.34
133_V	136_D	0.568	0.34
347_L	408_V	0.567	0.34
100_K	107_E	0.567	0.34
161_V	198_F	0.566	0.33
137_A	234_N	0.566	0.33
438_I	448_A	0.565	0.33
143_S	212_G	0.565	0.33
246_R	249_T	0.565	0.33
152_D	206_G	0.564	0.33
347_L	497_Y	0.564	0.33
139_F	178_F	0.563	0.33
197_G	252_A	0.563	0.33
365_P	519_K	0.563	0.33
134_V	138_I	0.561	0.33
274_L	328_L	0.561	0.33
395_R	482_L	0.560	0.33
255_R	512_V	0.560	0.33
279_N	286_Q	0.559	0.33
318_N	392_R	0.559	0.33
94_G	99_F	0.558	0.33
141_L	158_M	0.558	0.33
275_V	465_L	0.556	0.33
389_E	464_P	0.556	0.33
333_H	339_T	0.555	0.33
172_S	192_F	0.555	0.33
144_V	234_N	0.555	0.33
321_E	324_I	0.554	0.32
415_S	424_N	0.553	0.32
195_M	199_S	0.553	0.32
294_V	448_A	0.553	0.32
337_V	401_V	0.553	0.32
481_Y	494_V	0.553	0.32
411_I	508_R	0.553	0.32
421_I	500_K	0.552	0.32
477_L	499_L	0.552	0.32
233_F	508_R	0.552	0.32
363_G	366_L	0.551	0.32
453_P	472_H	0.551	0.32
299_Q	350_V	0.550	0.32
155_L	159_A	0.547	0.32
269_E	273_M	0.547	0.32
166_S	249_T	0.546	0.32
293_R	456_D	0.546	0.32
164_A	215_Y	0.544	0.32
175_L	401_V	0.544	0.32
493_Q	517_L	0.544	0.32
123_A	131_Q	0.543	0.32
231_A	237_R	0.543	0.32
345_E	421_I	0.543	0.32
175_L	372_I	0.542	0.31
144_V	202_A	0.542	0.31
150_M	212_G	0.542	0.31
168_M	176_T	0.541	0.31
263_D	455_E	0.540	0.31
499_L	509_V	0.539	0.31
449_N	511_K	0.539	0.31
156_V	159_A	0.538	0.31
161_V	202_A	0.537	0.31
264_A	350_V	0.536	0.31
212_G	247_Q	0.536	0.31
312_I	415_S	0.535	0.31
390_Q	474_I	0.534	0.31
354_I	485_I	0.533	0.31
273_M	485_I	0.533	0.31
196_I	199_S	0.533	0.31
120_R	123_A	0.533	0.31
376_L	399_A	0.532	0.31
320_P	327_L	0.532	0.31
291_I	388_L	0.531	0.31
339_T	421_I	0.528	0.30
309_R	416_D	0.527	0.30
360_S	454_L	0.526	0.30
203_E	247_Q	0.525	0.30
391_F	399_A	0.525	0.30
169_L	302_V	0.524	0.30
255_R	375_P	0.522	0.30
158_M	162_V	0.522	0.30
491_E	502_L	0.521	0.30
141_L	150_M	0.521	0.30
161_V	164_A	0.520	0.30
307_T	391_F	0.520	0.30
419_E	424_N	0.519	0.30
133_V	158_M	0.517	0.29
144_V	161_V	0.516	0.29
334_T	339_T	0.516	0.29
153_H	156_V	0.516	0.29
104_E	114_S	0.516	0.29
266_L	284_N	0.515	0.29
175_L	213_Y	0.514	0.29
167_L	280_Q	0.514	0.29
178_F	197_G	0.513	0.29
334_T	354_I	0.513	0.29
104_E	116_N	0.513	0.29
359_Q	474_I	0.512	0.29
318_N	342_D	0.511	0.29
161_V	195_M	0.511	0.29
149_G	163_I	0.510	0.29
142_D	156_V	0.509	0.29
200_L	204_G	0.509	0.29
306_M	499_L	0.509	0.29
252_A	255_R	0.508	0.29
388_L	472_H	0.506	0.29
96_F	105_L	0.506	0.29
171_A	189_C	0.506	0.29
178_F	185_I	0.505	0.29
285_P	487_K	0.504	0.28
156_V	203_E	0.502	0.28
156_V	479_M	0.501	0.28
373_R	428_E	0.501	0.28
155_L	164_A	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4hg0A	2	0.4383	100	0.68	Contact Map
3lhhA	1	0.2372	100	0.855	Contact Map
3ocoA	2	0.2562	99.9	0.864	Contact Map
3ocmA	5	0.2827	99.9	0.864	Contact Map
3oi8A	2	0.296	99.9	0.866	Contact Map
2v8qE	1	0.444	99.9	0.87	Contact Map
3dedA	2	0.1651	99.9	0.873	Contact Map
3lv9A	2	0.2467	99.9	0.873	Contact Map
3kxrA	3	0.3055	99.9	0.874	Contact Map
2pliA	4	0.1594	99.9	0.878	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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