WZC - ECOLI - GREMLIN Contacts

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WZC - Tyrosine-protein kinase wzc

UniProt:	P76387	Sequences: MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITTVFALCAVVYTFFATPIYSADALVQIEQNSGNSLVQDIGSALANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQVFTLNVLDNKNYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASPGSEFTVTKYSTLGMINQLQNSLTVTENGKDAGVLSLTYTGEDREQIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLYTKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKEQELKITEASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLLIDCDMRKGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13568
Length:	720 (682)
Sequences:	1616 (1257)
Seq/√Len:	48.1

ECOLI - WZC ETK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
605_D	636_Y	8.882	1.00
236_G	242_I	5.909	1.00
472_L	697_S	5.661	1.00
559_L	632_A	5.232	1.00
591_D	594_T	4.743	1.00
232_L	246_L	4.647	1.00
593_T	635_N	4.557	1.00
105_D	207_T	4.545	1.00
247_N	413_A	4.505	1.00
595_A	607_I	4.131	1.00
585_I	595_A	3.911	1.00
528_V	629_V	3.902	1.00
470_I	543_V	3.613	1.00
45_A	431_A	3.481	1.00
392_K	395_E	3.434	1.00
175_Q	178_Q	3.409	1.00
629_V	641_I	3.403	1.00
60_A	250_A	3.230	1.00
100_L	245_I	3.187	1.00
563_C	641_I	3.180	1.00
607_I	628_L	3.102	1.00
157_L	163_T	3.085	1.00
158_D	161_N	3.063	1.00
563_C	582_L	3.054	1.00
106_D	248_S	3.045	1.00
307_K	311_D	3.001	1.00
515_T	650_T	2.869	1.00
58_A	242_I	2.853	1.00
48_Y	52_A	2.786	1.00
584_E	611_Q	2.739	1.00
561_I	628_L	2.737	1.00
113_V	136_V	2.711	1.00
38_T	436_L	2.678	1.00
141_F	152_F	2.676	1.00
613_P	616_P	2.664	1.00
320_L	348_R	2.633	1.00
255_E	259_E	2.615	1.00
530_M	643_T	2.586	1.00
315_N	318_A	2.558	1.00
104_V	210_M	2.537	1.00
205_Y	210_M	2.497	1.00
248_S	251_R	2.495	1.00
319_Q	322_E	2.473	1.00
530_M	656_G	2.447	1.00
597_K	608_P	2.368	1.00
236_G	241_Q	2.361	1.00
544_C	640_L	2.358	1.00
565_M	583_S	2.343	1.00
598_P	605_D	2.319	1.00
154_L	189_V	2.274	1.00
323_L	327_E	2.259	1.00
19_D	22_R	2.248	1.00
561_I	641_I	2.237	1.00
552_S	604_F	2.233	1.00
330_I	333_L	2.202	1.00
161_N	173_R	2.185	1.00
37_I	41_F	2.168	1.00
527_N	633_S	2.158	1.00
559_L	636_Y	2.143	1.00
354_E	357_K	2.133	1.00
157_L	161_N	2.118	1.00
112_A	205_Y	2.118	1.00
57_S	233_T	2.116	1.00
333_L	336_K	2.098	1.00
468_A	513_L	2.098	1.00
565_M	644_P	2.095	1.00
459_L	676_V	2.087	1.00
585_I	607_I	2.067	1.00
41_F	438_L	2.065	1.00
336_K	339_P	2.062	1.00
220_V	230_L	2.056	1.00
89_A	228_G	2.036	1.00
528_V	633_S	2.032	1.00
592_I	596_A	2.017	1.00
163_T	173_R	2.016	0.99
631_W	635_N	2.010	0.99
117_T	126_D	2.005	0.99
92_Q	229_V	1.997	0.99
90_E	253_Y	1.995	0.99
162_Y	180_L	1.990	0.99
206_S	210_M	1.984	0.99
331_S	341_Y	1.981	0.99
576_T	606_L	1.973	0.99
551_I	640_L	1.934	0.99
42_A	432_I	1.930	0.99
632_A	639_V	1.900	0.99
383_Q	387_M	1.899	0.99
117_T	123_A	1.888	0.99
291_N	370_Q	1.884	0.99
334_Y	339_P	1.881	0.99
327_E	331_S	1.871	0.99
333_L	339_P	1.868	0.99
34_V	440_I	1.863	0.99
136_V	200_F	1.860	0.99
327_E	345_L	1.843	0.99
585_I	592_I	1.840	0.99
551_I	638_L	1.823	0.99
514_R	618_E	1.818	0.99
341_Y	345_L	1.815	0.99
590_G	595_A	1.813	0.99
214_L	234_Y	1.788	0.99
46_V	428_I	1.772	0.99
207_T	211_I	1.769	0.99
345_L	348_R	1.760	0.99
530_M	655_V	1.759	0.99
182_K	185_V	1.756	0.99
585_I	628_L	1.755	0.99
75_D	78_S	1.755	0.99
116_N	201_T	1.748	0.99
471_P	509_A	1.720	0.98
630_N	634_K	1.718	0.98
625_F	655_V	1.716	0.98
216_N	418_G	1.699	0.98
49_T	428_I	1.698	0.98
710_Y	715_Y	1.695	0.98
51_F	117_T	1.687	0.98
623_E	627_E	1.684	0.98
712_E	716_K	1.680	0.98
325_F	329_E	1.646	0.98
155_N	199_E	1.644	0.98
248_S	252_N	1.641	0.98
286_A	382_G	1.640	0.98
98_L	411_D	1.632	0.98
101_G	105_D	1.615	0.98
330_I	336_K	1.613	0.98
380_E	384_Q	1.606	0.97
561_I	639_V	1.604	0.97
470_I	513_L	1.602	0.97
294_R	369_Q	1.585	0.97
450_N	454_E	1.581	0.97
55_I	237_E	1.581	0.97
559_L	639_V	1.572	0.97
633_S	660_G	1.567	0.97
92_Q	223_N	1.561	0.97
629_V	658_H	1.557	0.97
106_D	252_N	1.557	0.97
62_V	94_I	1.555	0.97
555_N	602_A	1.553	0.97
627_E	631_W	1.532	0.97
50_F	117_T	1.513	0.96
153_T	199_E	1.511	0.96
304_L	307_K	1.510	0.96
533_G	538_I	1.498	0.96
334_Y	337_V	1.497	0.96
102_K	106_D	1.491	0.96
45_A	49_T	1.487	0.96
650_T	654_I	1.482	0.96
327_E	348_R	1.478	0.96
125_W	129_M	1.467	0.96
62_V	250_A	1.464	0.96
303_P	369_Q	1.459	0.95
628_L	632_A	1.459	0.95
534_V	538_I	1.455	0.95
625_F	629_V	1.445	0.95
49_T	427_I	1.443	0.95
370_Q	374_R	1.439	0.95
624_R	627_E	1.436	0.95
155_N	163_T	1.427	0.95
626_A	657_R	1.427	0.95
527_N	639_V	1.414	0.95
663_L	694_I	1.408	0.95
607_I	632_A	1.404	0.94
104_V	109_L	1.403	0.94
598_P	636_Y	1.398	0.94
45_A	427_I	1.398	0.94
574_L	604_F	1.392	0.94
548_A	560_L	1.391	0.94
291_N	295_Q	1.391	0.94
327_E	341_Y	1.386	0.94
51_F	123_A	1.382	0.94
110_D	204_K	1.376	0.94
462_H	693_V	1.375	0.94
127_R	241_Q	1.375	0.94
65_E	260_R	1.374	0.94
321_N	325_F	1.365	0.94
235_T	421_K	1.355	0.93
166_S	169_G	1.341	0.93
341_Y	348_R	1.341	0.93
592_I	607_I	1.340	0.93
234_Y	245_I	1.335	0.93
46_V	50_F	1.333	0.93
114_S	127_R	1.332	0.93
626_A	630_N	1.323	0.92
561_I	582_L	1.323	0.92
532_T	683_F	1.314	0.92
666_A	676_V	1.311	0.92
33_W	37_I	1.305	0.92
174_G	180_L	1.302	0.92
92_Q	95_R	1.302	0.92
712_E	715_Y	1.301	0.92
50_F	428_I	1.300	0.92
157_L	173_R	1.298	0.92
161_N	175_Q	1.297	0.92
626_A	658_H	1.292	0.92
47_V	51_F	1.287	0.91
27_V	440_I	1.286	0.91
179_M	188_M	1.285	0.91
380_E	383_Q	1.281	0.91
706_Q	709_G	1.276	0.91
438_L	442_G	1.275	0.91
646_I	653_A	1.268	0.91
129_M	244_D	1.263	0.91
116_N	199_E	1.260	0.90
162_Y	177_G	1.259	0.90
162_Y	176_A	1.254	0.90
659_V	662_T	1.252	0.90
664_M	679_S	1.250	0.90
331_S	336_K	1.246	0.90
592_I	632_A	1.244	0.90
628_L	639_V	1.241	0.90
623_E	626_A	1.238	0.90
156_V	192_I	1.233	0.89
630_N	633_S	1.228	0.89
530_M	652_A	1.227	0.89
24_V	28_I	1.227	0.89
48_Y	427_I	1.224	0.89
707_D	714_E	1.223	0.89
160_K	175_Q	1.221	0.89
103_T	252_N	1.221	0.89
224_G	227_A	1.217	0.89
293_F	297_K	1.215	0.89
57_S	235_T	1.215	0.89
217_S	234_Y	1.213	0.89
266_S	270_A	1.212	0.89
515_T	654_I	1.209	0.89
538_I	568_G	1.208	0.89
181_K	186_T	1.203	0.88
293_F	372_I	1.202	0.88
269_L	396_L	1.202	0.88
223_N	231_S	1.200	0.88
423_K	426_L	1.199	0.88
41_F	431_A	1.196	0.88
273_A	393_E	1.196	0.88
18_I	23_L	1.193	0.88
100_L	103_T	1.190	0.88
212_N	215_Q	1.185	0.88
156_V	176_A	1.183	0.87
50_F	123_A	1.183	0.87
26_T	447_S	1.180	0.87
270_A	274_Q	1.178	0.87
562_D	568_G	1.176	0.87
214_L	236_G	1.176	0.87
155_N	165_S	1.175	0.87
544_C	560_L	1.174	0.87
63_Q	89_A	1.171	0.87
618_E	649_V	1.168	0.87
592_I	635_N	1.166	0.87
241_Q	245_I	1.165	0.87
240_E	243_R	1.164	0.87
379_V	394_Q	1.152	0.86
101_G	211_I	1.147	0.86
388_Q	395_E	1.146	0.86
266_S	400_E	1.145	0.86
586_L	619_L	1.144	0.86
563_C	625_F	1.142	0.86
500_G	697_S	1.139	0.85
711_Y	716_K	1.131	0.85
60_A	246_L	1.131	0.85
599_T	604_F	1.129	0.85
320_L	352_E	1.122	0.84
137_K	190_E	1.121	0.84
213_Q	217_S	1.119	0.84
315_N	319_Q	1.118	0.84
178_Q	296_D	1.115	0.84
327_E	339_P	1.111	0.84
313_M	362_V	1.106	0.84
135_T	140_T	1.105	0.84
163_T	171_S	1.103	0.83
114_S	203_T	1.101	0.83
331_S	339_P	1.100	0.83
528_V	659_V	1.099	0.83
58_A	415_T	1.095	0.83
292_A	296_D	1.095	0.83
30_A	443_V	1.088	0.83
60_A	232_L	1.086	0.82
28_I	31_R	1.080	0.82
326_K	329_E	1.080	0.82
462_H	673_L	1.074	0.82
17_E	20_I	1.070	0.82
97_R	411_D	1.070	0.82
316_I	351_L	1.070	0.82
545_A	606_L	1.067	0.81
545_A	573_L	1.062	0.81
38_T	435_G	1.061	0.81
240_E	244_D	1.060	0.81
559_L	596_A	1.057	0.81
519_F	614_P	1.055	0.81
102_K	252_N	1.052	0.80
124_G	128_L	1.048	0.80
330_I	339_P	1.048	0.80
172_A	180_L	1.047	0.80
243_R	415_T	1.046	0.80
438_L	441_V	1.045	0.80
287_E	294_R	1.042	0.80
590_G	594_T	1.040	0.80
275_Q	394_Q	1.039	0.80
106_D	255_E	1.039	0.80
371_E	374_R	1.037	0.79
498_A	507_I	1.036	0.79
162_Y	174_G	1.034	0.79
662_T	690_V	1.033	0.79
372_I	376_T	1.031	0.79
504_D	507_I	1.028	0.79
225_K	253_Y	1.026	0.79
282_R	382_G	1.023	0.79
593_T	631_W	1.023	0.79
109_L	245_I	1.022	0.78
627_E	630_N	1.020	0.78
663_L	692_G	1.018	0.78
548_A	561_I	1.017	0.78
43_L	169_G	1.017	0.78
579_V	597_K	1.015	0.78
526_N	660_G	1.011	0.78
656_G	688_I	1.011	0.78
587_I	614_P	1.009	0.78
283_L	379_V	1.009	0.78
711_Y	714_E	1.007	0.77
335_T	339_P	1.004	0.77
512_S	650_T	1.002	0.77
151_V	203_T	1.002	0.77
434_L	441_V	1.001	0.77
560_L	606_L	1.000	0.77
541_T	636_Y	1.000	0.77
583_S	616_P	0.998	0.77
349_Q	353_D	0.997	0.77
430_G	434_L	0.996	0.77
124_G	129_M	0.995	0.77
542_F	546_N	0.992	0.76
379_V	382_G	0.989	0.76
99_V	249_I	0.987	0.76
378_D	382_G	0.986	0.76
102_K	105_D	0.980	0.75
333_L	337_V	0.979	0.75
272_L	393_E	0.976	0.75
72_L	75_D	0.975	0.75
220_V	246_L	0.973	0.75
337_V	342_R	0.973	0.75
576_T	597_K	0.973	0.75
263_A	267_K	0.972	0.75
601_I	604_F	0.971	0.75
467_Y	663_L	0.970	0.75
53_T	237_E	0.967	0.74
636_Y	639_V	0.960	0.74
21_G	25_G	0.959	0.74
514_R	621_M	0.958	0.74
329_E	333_L	0.957	0.74
466_V	695_L	0.955	0.74
335_T	338_H	0.954	0.73
212_N	216_N	0.953	0.73
100_L	104_V	0.950	0.73
585_I	624_R	0.946	0.73
49_T	431_A	0.944	0.73
668_Y	702_A	0.944	0.73
618_E	621_M	0.942	0.73
267_K	270_A	0.942	0.73
326_K	347_K	0.941	0.72
596_A	632_A	0.940	0.72
41_F	434_L	0.940	0.72
62_V	313_M	0.938	0.72
275_Q	309_V	0.937	0.72
265_A	570_T	0.937	0.72
413_A	504_D	0.936	0.72
563_C	655_V	0.936	0.72
560_L	570_T	0.934	0.72
311_D	315_N	0.932	0.72
532_T	662_T	0.931	0.72
123_A	129_M	0.931	0.72
543_V	665_V	0.926	0.71
35_I	588_G	0.919	0.71
92_Q	224_G	0.919	0.71
99_V	410_V	0.918	0.71
460_E	681_S	0.916	0.70
631_W	634_K	0.913	0.70
320_L	351_L	0.913	0.70
61_L	229_V	0.912	0.70
204_K	568_G	0.911	0.70
562_D	652_A	0.907	0.70
513_L	694_I	0.903	0.69
136_V	154_L	0.900	0.69
243_R	247_N	0.897	0.69
344_L	348_R	0.896	0.69
456_P	469_S	0.894	0.69
582_L	628_L	0.894	0.69
534_V	671_N	0.894	0.69
559_L	607_I	0.893	0.68
680_L	684_E	0.892	0.68
401_A	586_L	0.890	0.68
563_C	647_L	0.889	0.68
632_A	635_N	0.884	0.68
49_T	424_K	0.882	0.67
545_A	570_T	0.881	0.67
558_V	603_K	0.880	0.67
470_I	510_I	0.877	0.67
34_V	38_T	0.876	0.67
312_S	354_E	0.875	0.67
511_R	618_E	0.874	0.67
336_K	340_A	0.871	0.66
709_G	712_E	0.870	0.66
255_E	258_I	0.868	0.66
410_V	519_F	0.866	0.66
97_R	211_I	0.864	0.66
578_N	611_Q	0.862	0.66
168_G	171_S	0.861	0.66
271_F	283_L	0.861	0.66
667_R	697_S	0.860	0.65
323_L	348_R	0.860	0.65
199_E	234_Y	0.859	0.65
344_L	347_K	0.858	0.65
208_L	212_N	0.858	0.65
156_V	189_V	0.858	0.65
470_I	506_A	0.857	0.65
421_K	424_K	0.857	0.65
214_L	410_V	0.856	0.65
299_S	372_I	0.855	0.65
267_K	298_D	0.855	0.65
592_I	628_L	0.851	0.65
139_T	190_E	0.850	0.65
650_T	655_V	0.849	0.64
37_I	439_S	0.849	0.64
455_S	695_L	0.848	0.64
596_A	636_Y	0.847	0.64
636_Y	694_I	0.847	0.64
103_T	332_K	0.846	0.64
322_E	326_K	0.846	0.64
206_S	209_G	0.845	0.64
588_G	624_R	0.844	0.64
521_M	661_T	0.844	0.64
42_A	438_L	0.843	0.64
536_P	569_Y	0.843	0.64
429_L	433_I	0.838	0.63
456_P	459_L	0.838	0.63
581_G	610_G	0.836	0.63
242_I	294_R	0.834	0.63
515_T	519_F	0.833	0.63
282_R	458_V	0.833	0.63
217_S	236_G	0.832	0.63
327_E	336_K	0.830	0.63
386_Y	390_L	0.829	0.63
453_I	673_L	0.829	0.63
295_Q	367_K	0.828	0.63
63_Q	408_R	0.828	0.63
438_L	655_V	0.827	0.62
676_V	680_L	0.827	0.62
616_P	649_V	0.826	0.62
348_R	352_E	0.825	0.62
31_R	268_S	0.823	0.62
473_S	646_I	0.820	0.62
334_Y	338_H	0.819	0.62
613_P	649_V	0.819	0.62
132_Q	135_T	0.817	0.61
286_A	375_L	0.816	0.61
330_I	344_L	0.809	0.61
71_S	75_D	0.809	0.61
324_T	336_K	0.808	0.61
582_L	625_F	0.806	0.60
261_K	380_E	0.804	0.60
239_R	293_F	0.801	0.60
511_R	649_V	0.800	0.60
513_L	663_L	0.800	0.60
508_E	566_R	0.798	0.60
565_M	703_S	0.797	0.60
52_A	427_I	0.796	0.59
64_I	470_I	0.794	0.59
580_N	590_G	0.793	0.59
32_W	36_G	0.791	0.59
392_K	399_T	0.790	0.59
275_Q	382_G	0.786	0.58
395_E	403_T	0.784	0.58
30_A	446_R	0.783	0.58
33_W	442_G	0.783	0.58
405_G	408_R	0.780	0.58
220_V	594_T	0.779	0.58
220_V	234_Y	0.778	0.58
244_D	247_N	0.777	0.58
139_T	188_M	0.775	0.57
287_E	377_R	0.772	0.57
506_A	509_A	0.772	0.57
465_S	693_V	0.772	0.57
329_E	336_K	0.771	0.57
565_M	585_I	0.770	0.57
163_T	170_F	0.768	0.57
275_Q	387_M	0.768	0.57
141_F	144_P	0.767	0.57
444_L	448_L	0.764	0.56
36_G	39_T	0.764	0.56
58_A	236_G	0.763	0.56
437_M	441_V	0.762	0.56
504_D	568_G	0.760	0.56
458_V	461_E	0.760	0.56
294_R	305_E	0.759	0.56
565_M	650_T	0.758	0.56
615_N	649_V	0.756	0.56
260_R	275_Q	0.756	0.56
193_H	199_E	0.755	0.55
63_Q	93_L	0.754	0.55
95_R	662_T	0.754	0.55
49_T	52_A	0.753	0.55
98_L	365_M	0.753	0.55
47_V	50_F	0.752	0.55
593_T	596_A	0.751	0.55
644_P	652_A	0.750	0.55
388_Q	392_K	0.748	0.55
439_S	443_V	0.748	0.55
20_I	152_F	0.747	0.55
160_K	176_A	0.746	0.55
162_Y	570_T	0.745	0.54
703_S	706_Q	0.745	0.54
472_L	699_F	0.743	0.54
535_S	671_N	0.743	0.54
262_S	403_T	0.742	0.54
247_N	251_R	0.742	0.54
536_P	647_L	0.742	0.54
509_A	519_F	0.741	0.54
517_L	548_A	0.740	0.54
289_K	375_L	0.740	0.54
113_V	135_T	0.740	0.54
460_E	466_V	0.737	0.54
453_I	532_T	0.736	0.54
260_R	408_R	0.735	0.53
51_F	125_W	0.735	0.53
294_R	400_E	0.734	0.53
57_S	420_L	0.733	0.53
459_L	693_V	0.733	0.53
253_Y	422_P	0.733	0.53
100_L	215_Q	0.732	0.53
157_L	160_K	0.731	0.53
142_N	186_T	0.730	0.53
332_K	336_K	0.729	0.53
179_M	182_K	0.728	0.53
65_E	257_N	0.727	0.53
554_T	621_M	0.725	0.52
467_Y	520_A	0.724	0.52
305_E	460_E	0.724	0.52
565_M	588_G	0.724	0.52
561_I	627_E	0.721	0.52
695_L	698_I	0.720	0.52
236_G	245_I	0.719	0.52
382_G	393_E	0.719	0.52
142_N	164_L	0.718	0.52
376_T	392_K	0.718	0.52
352_E	357_K	0.718	0.52
13_T	40_V	0.718	0.52
520_A	692_G	0.716	0.52
473_S	504_D	0.716	0.52
676_V	683_F	0.714	0.51
309_V	398_I	0.714	0.51
519_F	646_I	0.712	0.51
103_T	248_S	0.712	0.51
204_K	210_M	0.712	0.51
316_I	355_K	0.710	0.51
596_A	607_I	0.710	0.51
102_K	256_Q	0.710	0.51
540_K	642_D	0.708	0.51
570_T	573_L	0.708	0.51
88_D	93_L	0.705	0.50
452_G	533_G	0.705	0.50
618_E	650_T	0.704	0.50
110_D	207_T	0.704	0.50
583_S	614_P	0.703	0.50
181_K	438_L	0.702	0.50
35_I	155_N	0.701	0.50
221_T	231_S	0.700	0.50
223_N	227_A	0.700	0.50
560_L	604_F	0.699	0.50
235_T	420_L	0.699	0.50
613_P	617_S	0.698	0.50
565_M	658_H	0.698	0.50
64_I	244_D	0.698	0.50
679_S	682_R	0.697	0.50
520_A	614_P	0.696	0.50
295_Q	348_R	0.696	0.50
534_V	664_M	0.694	0.49
31_R	35_I	0.691	0.49
257_N	375_L	0.690	0.49
541_T	605_D	0.690	0.49
532_T	597_K	0.690	0.49
273_A	397_K	0.689	0.49
545_A	572_E	0.689	0.49
42_A	49_T	0.688	0.49
623_E	711_Y	0.688	0.49
169_G	445_L	0.688	0.49
111_I	677_E	0.683	0.48
241_Q	244_D	0.683	0.48
313_M	317_D	0.683	0.48
97_R	414_I	0.682	0.48
282_R	317_D	0.681	0.48
218_L	249_I	0.681	0.48
633_S	639_V	0.680	0.48
236_G	294_R	0.680	0.48
327_E	333_L	0.680	0.48
335_T	341_Y	0.679	0.48
419_V	422_P	0.678	0.48
287_E	661_T	0.677	0.48
646_I	683_F	0.677	0.48
58_A	243_R	0.676	0.48
48_Y	543_V	0.675	0.47
615_N	618_E	0.673	0.47
500_G	694_I	0.671	0.47
100_L	590_G	0.671	0.47
262_S	267_K	0.670	0.47
320_L	446_R	0.670	0.47
465_S	632_A	0.669	0.47
675_E	692_G	0.668	0.47
88_D	227_A	0.668	0.47
75_D	79_A	0.667	0.47
305_E	620_L	0.667	0.47
42_A	428_I	0.667	0.47
320_L	355_K	0.666	0.47
126_D	129_M	0.665	0.46
254_Q	394_Q	0.665	0.46
582_L	586_L	0.665	0.46
214_L	245_I	0.665	0.46
519_F	615_N	0.665	0.46
331_S	337_V	0.664	0.46
519_F	613_P	0.663	0.46
552_S	555_N	0.663	0.46
540_K	649_V	0.662	0.46
254_Q	382_G	0.662	0.46
330_I	337_V	0.661	0.46
393_E	397_K	0.660	0.46
32_W	556_K	0.660	0.46
159_N	195_S	0.659	0.46
336_K	341_Y	0.659	0.46
299_S	565_M	0.659	0.46
95_R	430_G	0.658	0.46
163_T	424_K	0.658	0.46
258_I	262_S	0.658	0.46
87_S	250_A	0.658	0.46
205_Y	213_Q	0.658	0.46
343_T	346_E	0.657	0.46
64_I	89_A	0.657	0.46
612_V	628_L	0.656	0.46
369_Q	663_L	0.656	0.46
141_F	202_V	0.655	0.45
379_V	391_N	0.655	0.45
592_I	631_W	0.655	0.45
136_V	296_D	0.654	0.45
349_Q	557_R	0.653	0.45
613_P	619_L	0.653	0.45
551_I	565_M	0.652	0.45
568_G	648_A	0.652	0.45
565_M	613_P	0.652	0.45
507_I	664_M	0.651	0.45
497_L	506_A	0.651	0.45
354_E	361_R	0.650	0.45
63_Q	228_G	0.650	0.45
189_V	323_L	0.650	0.45
87_S	402_S	0.649	0.45
138_V	173_R	0.648	0.45
423_K	427_I	0.648	0.45
178_Q	188_M	0.648	0.45
187_L	330_I	0.647	0.45
441_V	445_L	0.647	0.45
396_L	550_V	0.647	0.45
275_Q	458_V	0.646	0.45
136_V	190_E	0.646	0.45
547_L	643_T	0.645	0.44
566_R	616_P	0.645	0.44
171_S	541_T	0.644	0.44
300_V	365_M	0.644	0.44
38_T	42_A	0.643	0.44
305_E	310_L	0.643	0.44
446_R	584_E	0.643	0.44
560_L	640_L	0.642	0.44
41_F	428_I	0.642	0.44
596_A	635_N	0.641	0.44
433_I	594_T	0.641	0.44
165_S	171_S	0.639	0.44
24_V	554_T	0.639	0.44
530_M	641_I	0.639	0.44
652_A	675_E	0.638	0.44
61_L	231_S	0.638	0.44
470_I	627_E	0.638	0.44
325_F	332_K	0.638	0.44
471_P	562_D	0.638	0.44
551_I	694_I	0.637	0.44
136_V	595_A	0.637	0.44
154_L	194_A	0.637	0.44
419_V	424_K	0.637	0.44
35_I	684_E	0.636	0.44
559_L	582_L	0.636	0.44
125_W	128_L	0.636	0.44
384_Q	391_N	0.635	0.43
292_A	297_K	0.635	0.43
527_N	660_G	0.632	0.43
164_L	174_G	0.632	0.43
514_R	566_R	0.631	0.43
27_V	34_V	0.631	0.43
151_V	162_Y	0.631	0.43
309_V	362_V	0.630	0.43
529_L	681_S	0.630	0.43
164_L	189_V	0.630	0.43
570_T	606_L	0.629	0.43
508_E	564_D	0.629	0.43
100_L	211_I	0.627	0.43
506_A	510_I	0.627	0.43
514_R	617_S	0.626	0.43
254_Q	275_Q	0.626	0.43
516_S	687_G	0.625	0.42
560_L	636_Y	0.625	0.42
545_A	574_L	0.623	0.42
315_N	694_I	0.622	0.42
406_D	554_T	0.622	0.42
227_A	267_K	0.620	0.42
352_E	356_A	0.620	0.42
254_Q	407_V	0.618	0.42
610_G	645_P	0.617	0.42
390_L	393_E	0.617	0.42
177_G	190_E	0.617	0.42
383_Q	509_A	0.617	0.42
242_I	403_T	0.616	0.42
668_Y	699_F	0.616	0.42
647_L	692_G	0.616	0.42
91_I	220_V	0.616	0.42
94_I	218_L	0.616	0.42
155_N	457_Q	0.615	0.41
62_V	331_S	0.615	0.41
232_L	293_F	0.615	0.41
140_T	179_M	0.615	0.41
229_V	305_E	0.614	0.41
250_A	254_Q	0.614	0.41
438_L	577_N	0.614	0.41
19_D	34_V	0.613	0.41
278_E	293_F	0.613	0.41
330_I	334_Y	0.613	0.41
371_E	639_V	0.612	0.41
81_A	84_P	0.612	0.41
154_L	202_V	0.612	0.41
104_V	199_E	0.612	0.41
82_N	664_M	0.611	0.41
15_S	20_I	0.611	0.41
312_S	315_N	0.611	0.41
304_L	308_A	0.611	0.41
562_D	612_V	0.611	0.41
67_N	433_I	0.610	0.41
23_L	445_L	0.610	0.41
65_E	228_G	0.610	0.41
514_R	615_N	0.610	0.41
66_Q	219_T	0.610	0.41
44_C	418_G	0.609	0.41
466_V	671_N	0.609	0.41
686_N	694_I	0.609	0.41
521_M	529_L	0.609	0.41
437_M	662_T	0.608	0.41
370_Q	382_G	0.607	0.41
241_Q	358_L	0.606	0.41
170_F	173_R	0.606	0.41
461_E	609_R	0.605	0.40
636_Y	665_V	0.605	0.40
72_L	265_A	0.604	0.40
139_T	219_T	0.604	0.40
435_G	439_S	0.604	0.40
434_L	440_I	0.602	0.40
520_A	627_E	0.602	0.40
450_N	470_I	0.601	0.40
548_A	562_D	0.600	0.40
367_K	371_E	0.600	0.40
508_E	649_V	0.599	0.40
560_L	620_L	0.599	0.40
662_T	688_I	0.599	0.40
389_L	697_S	0.597	0.40
100_L	214_L	0.594	0.39
101_G	207_T	0.594	0.39
616_P	619_L	0.594	0.39
290_L	308_A	0.593	0.39
299_S	306_A	0.592	0.39
411_D	620_L	0.592	0.39
541_T	642_D	0.591	0.39
173_R	574_L	0.590	0.39
262_S	392_K	0.590	0.39
530_M	662_T	0.590	0.39
129_M	132_Q	0.588	0.39
269_L	365_M	0.588	0.39
48_Y	410_V	0.588	0.39
471_P	571_H	0.588	0.39
174_G	177_G	0.587	0.39
29_E	451_R	0.587	0.39
577_N	591_D	0.586	0.39
135_T	138_V	0.585	0.39
194_A	200_F	0.585	0.39
713_Y	716_K	0.584	0.38
532_T	664_M	0.583	0.38
672_T	675_E	0.583	0.38
609_R	612_V	0.583	0.38
614_P	691_K	0.582	0.38
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352_E	440_I	0.581	0.38
189_V	638_L	0.581	0.38
627_E	694_I	0.580	0.38
169_G	176_A	0.580	0.38
376_T	383_Q	0.579	0.38
30_A	663_L	0.579	0.38
614_P	618_E	0.579	0.38
280_R	284_D	0.579	0.38
292_A	295_Q	0.578	0.38
164_L	173_R	0.577	0.38
209_G	213_Q	0.577	0.38
372_I	391_N	0.577	0.38
596_A	605_D	0.575	0.38
624_R	641_I	0.574	0.38
123_A	127_R	0.574	0.38
39_T	561_I	0.574	0.38
187_L	202_V	0.573	0.37
589_Q	617_S	0.573	0.37
559_L	605_D	0.573	0.37
666_A	693_V	0.573	0.37
267_K	272_L	0.572	0.37
640_L	694_I	0.572	0.37
245_I	249_I	0.571	0.37
71_S	261_K	0.570	0.37
67_N	261_K	0.570	0.37
39_T	68_S	0.570	0.37
258_I	403_T	0.569	0.37
179_M	560_L	0.569	0.37
279_V	385_V	0.569	0.37
564_D	645_P	0.568	0.37
567_K	653_A	0.568	0.37
384_Q	555_N	0.568	0.37
257_N	407_V	0.567	0.37
26_T	30_A	0.567	0.37
453_I	602_A	0.567	0.37
505_L	512_S	0.567	0.37
535_S	648_A	0.567	0.37
285_V	289_K	0.565	0.37
397_K	400_E	0.564	0.37
517_L	661_T	0.564	0.37
16_D	23_L	0.563	0.36
234_Y	448_L	0.563	0.36
33_W	710_Y	0.563	0.36
104_V	207_T	0.563	0.36
132_Q	195_S	0.562	0.36
436_L	440_I	0.562	0.36
40_V	44_C	0.562	0.36
261_K	362_V	0.561	0.36
566_R	649_V	0.561	0.36
43_L	593_T	0.560	0.36
531_M	663_L	0.560	0.36
324_T	331_S	0.559	0.36
301_D	304_L	0.559	0.36
19_D	671_N	0.559	0.36
592_I	598_P	0.559	0.36
270_A	523_Q	0.559	0.36
93_L	459_L	0.559	0.36
329_E	332_K	0.558	0.36
578_N	609_R	0.558	0.36
424_K	428_I	0.557	0.36
108_D	137_K	0.556	0.36
471_P	536_P	0.555	0.36
341_Y	369_Q	0.555	0.36
51_F	118_F	0.555	0.36
683_F	691_K	0.554	0.36
348_R	417_P	0.554	0.36
614_P	649_V	0.553	0.36
156_V	160_K	0.553	0.36
33_W	560_L	0.552	0.35
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248_S	635_N	0.552	0.35
415_T	671_N	0.552	0.35
217_S	627_E	0.551	0.35
164_L	172_A	0.551	0.35
344_L	471_P	0.551	0.35
155_N	196_P	0.551	0.35
557_R	597_K	0.550	0.35
608_P	613_P	0.550	0.35
536_P	555_N	0.550	0.35
24_V	544_C	0.549	0.35
525_Q	626_A	0.549	0.35
106_D	453_I	0.549	0.35
275_Q	397_K	0.548	0.35
647_L	679_S	0.548	0.35
430_G	448_L	0.548	0.35
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576_T	608_P	0.547	0.35
319_Q	328_A	0.547	0.35
289_K	393_E	0.546	0.35
300_V	306_A	0.544	0.35
402_S	405_G	0.544	0.35
321_N	324_T	0.543	0.35
569_Y	572_E	0.543	0.35
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350_A	354_E	0.542	0.35
224_G	317_D	0.542	0.35
375_L	439_S	0.542	0.35
221_T	425_G	0.541	0.34
501_N	650_T	0.541	0.34
501_N	646_I	0.541	0.34
413_A	419_V	0.540	0.34
304_L	409_I	0.540	0.34
173_R	627_E	0.540	0.34
153_T	163_T	0.539	0.34
112_A	203_T	0.539	0.34
83_K	241_Q	0.539	0.34
320_L	408_R	0.539	0.34
25_G	28_I	0.538	0.34
553_Q	647_L	0.538	0.34
153_T	165_S	0.538	0.34
432_I	436_L	0.537	0.34
221_T	440_I	0.537	0.34
192_I	448_L	0.537	0.34
313_M	318_A	0.536	0.34
462_H	680_L	0.536	0.34
538_I	697_S	0.535	0.34
453_I	575_G	0.535	0.34
90_E	271_F	0.534	0.34
104_V	513_L	0.534	0.34
232_L	628_L	0.534	0.34
35_I	180_L	0.533	0.34
268_S	385_V	0.533	0.34
519_F	618_E	0.533	0.34
209_G	602_A	0.532	0.34
508_E	616_P	0.532	0.34
264_E	384_Q	0.532	0.34
583_S	613_P	0.532	0.34
82_N	227_A	0.532	0.34
668_Y	676_V	0.530	0.33
27_V	644_P	0.530	0.33
565_M	646_I	0.530	0.33
132_Q	198_S	0.530	0.33
144_P	198_S	0.529	0.33
176_A	191_A	0.529	0.33
343_T	547_L	0.529	0.33
562_D	609_R	0.529	0.33
260_R	650_T	0.529	0.33
165_S	360_G	0.528	0.33
216_N	557_R	0.528	0.33
138_V	169_G	0.528	0.33
108_D	301_D	0.526	0.33
642_D	696_N	0.526	0.33
59_D	231_S	0.526	0.33
248_S	330_I	0.525	0.33
459_L	462_H	0.525	0.33
221_T	434_L	0.525	0.33
505_L	582_L	0.525	0.33
456_P	460_E	0.524	0.33
568_G	609_R	0.524	0.33
230_L	245_I	0.524	0.33
152_F	164_L	0.523	0.33
74_Q	78_S	0.523	0.33
671_N	674_K	0.523	0.33
277_P	396_L	0.522	0.33
290_L	647_L	0.522	0.33
104_V	621_M	0.522	0.33
394_Q	469_S	0.522	0.33
216_N	219_T	0.522	0.33
57_S	453_I	0.521	0.33
644_P	654_I	0.521	0.33
540_K	566_R	0.521	0.33
59_D	223_N	0.520	0.33
339_P	346_E	0.520	0.33
339_P	347_K	0.520	0.33
89_A	99_V	0.519	0.32
376_T	458_V	0.519	0.32
383_Q	392_K	0.519	0.32
323_L	347_K	0.519	0.32
225_K	438_L	0.519	0.32
36_G	220_V	0.518	0.32
579_V	592_I	0.518	0.32
33_W	36_G	0.518	0.32
33_W	443_V	0.517	0.32
531_M	643_T	0.517	0.32
244_D	537_S	0.517	0.32
512_S	574_L	0.517	0.32
525_Q	561_I	0.516	0.32
317_D	354_E	0.515	0.32
367_K	383_Q	0.515	0.32
382_G	385_V	0.515	0.32
449_F	669_A	0.515	0.32
533_G	540_K	0.515	0.32
459_L	695_L	0.514	0.32
124_G	127_R	0.514	0.32
457_Q	695_L	0.514	0.32
34_V	94_I	0.514	0.32
327_E	330_I	0.514	0.32
331_S	470_I	0.514	0.32
426_L	430_G	0.514	0.32
436_L	556_K	0.514	0.32
70_N	78_S	0.514	0.32
290_L	376_T	0.514	0.32
368_T	382_G	0.514	0.32
191_A	661_T	0.513	0.32
209_G	418_G	0.512	0.32
229_V	431_A	0.512	0.32
242_I	415_T	0.512	0.32
45_A	428_I	0.512	0.32
465_S	667_R	0.512	0.32
540_K	645_P	0.512	0.32
590_G	624_R	0.511	0.32
272_L	392_K	0.511	0.32
509_A	562_D	0.511	0.32
140_T	188_M	0.510	0.32
133_N	195_S	0.510	0.32
640_L	663_L	0.509	0.32
321_N	329_E	0.509	0.32
123_A	714_E	0.509	0.32
279_V	389_L	0.509	0.32
276_L	377_R	0.508	0.32
202_V	455_S	0.508	0.32
139_T	246_L	0.507	0.31
340_A	431_A	0.506	0.31
578_N	597_K	0.506	0.31
524_A	588_G	0.506	0.31
151_V	189_V	0.505	0.31
257_N	406_D	0.505	0.31
156_V	194_A	0.505	0.31
55_I	596_A	0.505	0.31
103_T	583_S	0.504	0.31
450_N	676_V	0.504	0.31
64_I	533_G	0.503	0.31
164_L	594_T	0.503	0.31
410_V	544_C	0.503	0.31
425_G	429_L	0.502	0.31
187_L	441_V	0.502	0.31
212_N	418_G	0.502	0.31
239_R	242_I	0.502	0.31
574_L	686_N	0.502	0.31
557_R	700_R	0.502	0.31
323_L	344_L	0.501	0.31
507_I	677_E	0.501	0.31
237_E	577_N	0.500	0.31
680_L	683_F	0.500	0.31
324_T	327_E	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3la6A	4	0.3653	100	0.691	Contact Map
3cioA	2	0.3583	100	0.692	Contact Map
4jlvA	1	0.3153	100	0.716	Contact Map
4jmpA	1	0.3125	100	0.721	Contact Map
4wl1A	3	0.3028	100	0.828	Contact Map
4rz3A	2	0.2694	100	0.842	Contact Map
3fkqA	2	0.4333	100	0.845	Contact Map
3ug7A	4	0.2875	100	0.85	Contact Map
1g3qA	1	0.2694	100	0.854	Contact Map
1hyqA	1	0.2667	100	0.858	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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