GREMLIN Database
WZC - Tyrosine-protein kinase wzc
UniProt: P76387 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13568
Length: 720 (682)
Sequences: 1616 (1257)
Seq/√Len: 48.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
605_D636_Y8.8821.00
236_G242_I5.9091.00
472_L697_S5.6611.00
559_L632_A5.2321.00
591_D594_T4.7431.00
232_L246_L4.6471.00
593_T635_N4.5571.00
105_D207_T4.5451.00
247_N413_A4.5051.00
595_A607_I4.1311.00
585_I595_A3.9111.00
528_V629_V3.9021.00
470_I543_V3.6131.00
45_A431_A3.4811.00
392_K395_E3.4341.00
175_Q178_Q3.4091.00
629_V641_I3.4031.00
60_A250_A3.2301.00
100_L245_I3.1871.00
563_C641_I3.1801.00
607_I628_L3.1021.00
157_L163_T3.0851.00
158_D161_N3.0631.00
563_C582_L3.0541.00
106_D248_S3.0451.00
307_K311_D3.0011.00
515_T650_T2.8691.00
58_A242_I2.8531.00
48_Y52_A2.7861.00
584_E611_Q2.7391.00
561_I628_L2.7371.00
113_V136_V2.7111.00
38_T436_L2.6781.00
141_F152_F2.6761.00
613_P616_P2.6641.00
320_L348_R2.6331.00
255_E259_E2.6151.00
530_M643_T2.5861.00
315_N318_A2.5581.00
104_V210_M2.5371.00
205_Y210_M2.4971.00
248_S251_R2.4951.00
319_Q322_E2.4731.00
530_M656_G2.4471.00
597_K608_P2.3681.00
236_G241_Q2.3611.00
544_C640_L2.3581.00
565_M583_S2.3431.00
598_P605_D2.3191.00
154_L189_V2.2741.00
323_L327_E2.2591.00
19_D22_R2.2481.00
561_I641_I2.2371.00
552_S604_F2.2331.00
330_I333_L2.2021.00
161_N173_R2.1851.00
37_I41_F2.1681.00
527_N633_S2.1581.00
559_L636_Y2.1431.00
354_E357_K2.1331.00
157_L161_N2.1181.00
112_A205_Y2.1181.00
57_S233_T2.1161.00
333_L336_K2.0981.00
468_A513_L2.0981.00
565_M644_P2.0951.00
459_L676_V2.0871.00
585_I607_I2.0671.00
41_F438_L2.0651.00
336_K339_P2.0621.00
220_V230_L2.0561.00
89_A228_G2.0361.00
528_V633_S2.0321.00
592_I596_A2.0171.00
163_T173_R2.0160.99
631_W635_N2.0100.99
117_T126_D2.0050.99
92_Q229_V1.9970.99
90_E253_Y1.9950.99
162_Y180_L1.9900.99
206_S210_M1.9840.99
331_S341_Y1.9810.99
576_T606_L1.9730.99
551_I640_L1.9340.99
42_A432_I1.9300.99
632_A639_V1.9000.99
383_Q387_M1.8990.99
117_T123_A1.8880.99
291_N370_Q1.8840.99
334_Y339_P1.8810.99
327_E331_S1.8710.99
333_L339_P1.8680.99
34_V440_I1.8630.99
136_V200_F1.8600.99
327_E345_L1.8430.99
585_I592_I1.8400.99
551_I638_L1.8230.99
514_R618_E1.8180.99
341_Y345_L1.8150.99
590_G595_A1.8130.99
214_L234_Y1.7880.99
46_V428_I1.7720.99
207_T211_I1.7690.99
345_L348_R1.7600.99
530_M655_V1.7590.99
182_K185_V1.7560.99
585_I628_L1.7550.99
75_D78_S1.7550.99
116_N201_T1.7480.99
471_P509_A1.7200.98
630_N634_K1.7180.98
625_F655_V1.7160.98
216_N418_G1.6990.98
49_T428_I1.6980.98
710_Y715_Y1.6950.98
51_F117_T1.6870.98
623_E627_E1.6840.98
712_E716_K1.6800.98
325_F329_E1.6460.98
155_N199_E1.6440.98
248_S252_N1.6410.98
286_A382_G1.6400.98
98_L411_D1.6320.98
101_G105_D1.6150.98
330_I336_K1.6130.98
380_E384_Q1.6060.97
561_I639_V1.6040.97
470_I513_L1.6020.97
294_R369_Q1.5850.97
450_N454_E1.5810.97
55_I237_E1.5810.97
559_L639_V1.5720.97
633_S660_G1.5670.97
92_Q223_N1.5610.97
629_V658_H1.5570.97
106_D252_N1.5570.97
62_V94_I1.5550.97
555_N602_A1.5530.97
627_E631_W1.5320.97
50_F117_T1.5130.96
153_T199_E1.5110.96
304_L307_K1.5100.96
533_G538_I1.4980.96
334_Y337_V1.4970.96
102_K106_D1.4910.96
45_A49_T1.4870.96
650_T654_I1.4820.96
327_E348_R1.4780.96
125_W129_M1.4670.96
62_V250_A1.4640.96
303_P369_Q1.4590.95
628_L632_A1.4590.95
534_V538_I1.4550.95
625_F629_V1.4450.95
49_T427_I1.4430.95
370_Q374_R1.4390.95
624_R627_E1.4360.95
155_N163_T1.4270.95
626_A657_R1.4270.95
527_N639_V1.4140.95
663_L694_I1.4080.95
607_I632_A1.4040.94
104_V109_L1.4030.94
598_P636_Y1.3980.94
45_A427_I1.3980.94
574_L604_F1.3920.94
548_A560_L1.3910.94
291_N295_Q1.3910.94
327_E341_Y1.3860.94
51_F123_A1.3820.94
110_D204_K1.3760.94
462_H693_V1.3750.94
127_R241_Q1.3750.94
65_E260_R1.3740.94
321_N325_F1.3650.94
235_T421_K1.3550.93
166_S169_G1.3410.93
341_Y348_R1.3410.93
592_I607_I1.3400.93
234_Y245_I1.3350.93
46_V50_F1.3330.93
114_S127_R1.3320.93
626_A630_N1.3230.92
561_I582_L1.3230.92
532_T683_F1.3140.92
666_A676_V1.3110.92
33_W37_I1.3050.92
174_G180_L1.3020.92
92_Q95_R1.3020.92
712_E715_Y1.3010.92
50_F428_I1.3000.92
157_L173_R1.2980.92
161_N175_Q1.2970.92
626_A658_H1.2920.92
47_V51_F1.2870.91
27_V440_I1.2860.91
179_M188_M1.2850.91
380_E383_Q1.2810.91
706_Q709_G1.2760.91
438_L442_G1.2750.91
646_I653_A1.2680.91
129_M244_D1.2630.91
116_N199_E1.2600.90
162_Y177_G1.2590.90
162_Y176_A1.2540.90
659_V662_T1.2520.90
664_M679_S1.2500.90
331_S336_K1.2460.90
592_I632_A1.2440.90
628_L639_V1.2410.90
623_E626_A1.2380.90
156_V192_I1.2330.89
630_N633_S1.2280.89
530_M652_A1.2270.89
24_V28_I1.2270.89
48_Y427_I1.2240.89
707_D714_E1.2230.89
160_K175_Q1.2210.89
103_T252_N1.2210.89
224_G227_A1.2170.89
293_F297_K1.2150.89
57_S235_T1.2150.89
217_S234_Y1.2130.89
266_S270_A1.2120.89
515_T654_I1.2090.89
538_I568_G1.2080.89
181_K186_T1.2030.88
293_F372_I1.2020.88
269_L396_L1.2020.88
223_N231_S1.2000.88
423_K426_L1.1990.88
41_F431_A1.1960.88
273_A393_E1.1960.88
18_I23_L1.1930.88
100_L103_T1.1900.88
212_N215_Q1.1850.88
156_V176_A1.1830.87
50_F123_A1.1830.87
26_T447_S1.1800.87
270_A274_Q1.1780.87
562_D568_G1.1760.87
214_L236_G1.1760.87
155_N165_S1.1750.87
544_C560_L1.1740.87
63_Q89_A1.1710.87
618_E649_V1.1680.87
592_I635_N1.1660.87
241_Q245_I1.1650.87
240_E243_R1.1640.87
379_V394_Q1.1520.86
101_G211_I1.1470.86
388_Q395_E1.1460.86
266_S400_E1.1450.86
586_L619_L1.1440.86
563_C625_F1.1420.86
500_G697_S1.1390.85
711_Y716_K1.1310.85
60_A246_L1.1310.85
599_T604_F1.1290.85
320_L352_E1.1220.84
137_K190_E1.1210.84
213_Q217_S1.1190.84
315_N319_Q1.1180.84
178_Q296_D1.1150.84
327_E339_P1.1110.84
313_M362_V1.1060.84
135_T140_T1.1050.84
163_T171_S1.1030.83
114_S203_T1.1010.83
331_S339_P1.1000.83
528_V659_V1.0990.83
58_A415_T1.0950.83
292_A296_D1.0950.83
30_A443_V1.0880.83
60_A232_L1.0860.82
28_I31_R1.0800.82
326_K329_E1.0800.82
462_H673_L1.0740.82
17_E20_I1.0700.82
97_R411_D1.0700.82
316_I351_L1.0700.82
545_A606_L1.0670.81
545_A573_L1.0620.81
38_T435_G1.0610.81
240_E244_D1.0600.81
559_L596_A1.0570.81
519_F614_P1.0550.81
102_K252_N1.0520.80
124_G128_L1.0480.80
330_I339_P1.0480.80
172_A180_L1.0470.80
243_R415_T1.0460.80
438_L441_V1.0450.80
287_E294_R1.0420.80
590_G594_T1.0400.80
275_Q394_Q1.0390.80
106_D255_E1.0390.80
371_E374_R1.0370.79
498_A507_I1.0360.79
162_Y174_G1.0340.79
662_T690_V1.0330.79
372_I376_T1.0310.79
504_D507_I1.0280.79
225_K253_Y1.0260.79
282_R382_G1.0230.79
593_T631_W1.0230.79
109_L245_I1.0220.78
627_E630_N1.0200.78
663_L692_G1.0180.78
548_A561_I1.0170.78
43_L169_G1.0170.78
579_V597_K1.0150.78
526_N660_G1.0110.78
656_G688_I1.0110.78
587_I614_P1.0090.78
283_L379_V1.0090.78
711_Y714_E1.0070.77
335_T339_P1.0040.77
512_S650_T1.0020.77
151_V203_T1.0020.77
434_L441_V1.0010.77
560_L606_L1.0000.77
541_T636_Y1.0000.77
583_S616_P0.9980.77
349_Q353_D0.9970.77
430_G434_L0.9960.77
124_G129_M0.9950.77
542_F546_N0.9920.76
379_V382_G0.9890.76
99_V249_I0.9870.76
378_D382_G0.9860.76
102_K105_D0.9800.75
333_L337_V0.9790.75
272_L393_E0.9760.75
72_L75_D0.9750.75
220_V246_L0.9730.75
337_V342_R0.9730.75
576_T597_K0.9730.75
263_A267_K0.9720.75
601_I604_F0.9710.75
467_Y663_L0.9700.75
53_T237_E0.9670.74
636_Y639_V0.9600.74
21_G25_G0.9590.74
514_R621_M0.9580.74
329_E333_L0.9570.74
466_V695_L0.9550.74
335_T338_H0.9540.73
212_N216_N0.9530.73
100_L104_V0.9500.73
585_I624_R0.9460.73
49_T431_A0.9440.73
668_Y702_A0.9440.73
618_E621_M0.9420.73
267_K270_A0.9420.73
326_K347_K0.9410.72
596_A632_A0.9400.72
41_F434_L0.9400.72
62_V313_M0.9380.72
275_Q309_V0.9370.72
265_A570_T0.9370.72
413_A504_D0.9360.72
563_C655_V0.9360.72
560_L570_T0.9340.72
311_D315_N0.9320.72
532_T662_T0.9310.72
123_A129_M0.9310.72
543_V665_V0.9260.71
35_I588_G0.9190.71
92_Q224_G0.9190.71
99_V410_V0.9180.71
460_E681_S0.9160.70
631_W634_K0.9130.70
320_L351_L0.9130.70
61_L229_V0.9120.70
204_K568_G0.9110.70
562_D652_A0.9070.70
513_L694_I0.9030.69
136_V154_L0.9000.69
243_R247_N0.8970.69
344_L348_R0.8960.69
456_P469_S0.8940.69
582_L628_L0.8940.69
534_V671_N0.8940.69
559_L607_I0.8930.68
680_L684_E0.8920.68
401_A586_L0.8900.68
563_C647_L0.8890.68
632_A635_N0.8840.68
49_T424_K0.8820.67
545_A570_T0.8810.67
558_V603_K0.8800.67
470_I510_I0.8770.67
34_V38_T0.8760.67
312_S354_E0.8750.67
511_R618_E0.8740.67
336_K340_A0.8710.66
709_G712_E0.8700.66
255_E258_I0.8680.66
410_V519_F0.8660.66
97_R211_I0.8640.66
578_N611_Q0.8620.66
168_G171_S0.8610.66
271_F283_L0.8610.66
667_R697_S0.8600.65
323_L348_R0.8600.65
199_E234_Y0.8590.65
344_L347_K0.8580.65
208_L212_N0.8580.65
156_V189_V0.8580.65
470_I506_A0.8570.65
421_K424_K0.8570.65
214_L410_V0.8560.65
299_S372_I0.8550.65
267_K298_D0.8550.65
592_I628_L0.8510.65
139_T190_E0.8500.65
650_T655_V0.8490.64
37_I439_S0.8490.64
455_S695_L0.8480.64
596_A636_Y0.8470.64
636_Y694_I0.8470.64
103_T332_K0.8460.64
322_E326_K0.8460.64
206_S209_G0.8450.64
588_G624_R0.8440.64
521_M661_T0.8440.64
42_A438_L0.8430.64
536_P569_Y0.8430.64
429_L433_I0.8380.63
456_P459_L0.8380.63
581_G610_G0.8360.63
242_I294_R0.8340.63
515_T519_F0.8330.63
282_R458_V0.8330.63
217_S236_G0.8320.63
327_E336_K0.8300.63
386_Y390_L0.8290.63
453_I673_L0.8290.63
295_Q367_K0.8280.63
63_Q408_R0.8280.63
438_L655_V0.8270.62
676_V680_L0.8270.62
616_P649_V0.8260.62
348_R352_E0.8250.62
31_R268_S0.8230.62
473_S646_I0.8200.62
334_Y338_H0.8190.62
613_P649_V0.8190.62
132_Q135_T0.8170.61
286_A375_L0.8160.61
330_I344_L0.8090.61
71_S75_D0.8090.61
324_T336_K0.8080.61
582_L625_F0.8060.60
261_K380_E0.8040.60
239_R293_F0.8010.60
511_R649_V0.8000.60
513_L663_L0.8000.60
508_E566_R0.7980.60
565_M703_S0.7970.60
52_A427_I0.7960.59
64_I470_I0.7940.59
580_N590_G0.7930.59
32_W36_G0.7910.59
392_K399_T0.7900.59
275_Q382_G0.7860.58
395_E403_T0.7840.58
30_A446_R0.7830.58
33_W442_G0.7830.58
405_G408_R0.7800.58
220_V594_T0.7790.58
220_V234_Y0.7780.58
244_D247_N0.7770.58
139_T188_M0.7750.57
287_E377_R0.7720.57
506_A509_A0.7720.57
465_S693_V0.7720.57
329_E336_K0.7710.57
565_M585_I0.7700.57
163_T170_F0.7680.57
275_Q387_M0.7680.57
141_F144_P0.7670.57
444_L448_L0.7640.56
36_G39_T0.7640.56
58_A236_G0.7630.56
437_M441_V0.7620.56
504_D568_G0.7600.56
458_V461_E0.7600.56
294_R305_E0.7590.56
565_M650_T0.7580.56
615_N649_V0.7560.56
260_R275_Q0.7560.56
193_H199_E0.7550.55
63_Q93_L0.7540.55
95_R662_T0.7540.55
49_T52_A0.7530.55
98_L365_M0.7530.55
47_V50_F0.7520.55
593_T596_A0.7510.55
644_P652_A0.7500.55
388_Q392_K0.7480.55
439_S443_V0.7480.55
20_I152_F0.7470.55
160_K176_A0.7460.55
162_Y570_T0.7450.54
703_S706_Q0.7450.54
472_L699_F0.7430.54
535_S671_N0.7430.54
262_S403_T0.7420.54
247_N251_R0.7420.54
536_P647_L0.7420.54
509_A519_F0.7410.54
517_L548_A0.7400.54
289_K375_L0.7400.54
113_V135_T0.7400.54
460_E466_V0.7370.54
453_I532_T0.7360.54
260_R408_R0.7350.53
51_F125_W0.7350.53
294_R400_E0.7340.53
57_S420_L0.7330.53
459_L693_V0.7330.53
253_Y422_P0.7330.53
100_L215_Q0.7320.53
157_L160_K0.7310.53
142_N186_T0.7300.53
332_K336_K0.7290.53
179_M182_K0.7280.53
65_E257_N0.7270.53
554_T621_M0.7250.52
467_Y520_A0.7240.52
305_E460_E0.7240.52
565_M588_G0.7240.52
561_I627_E0.7210.52
695_L698_I0.7200.52
236_G245_I0.7190.52
382_G393_E0.7190.52
142_N164_L0.7180.52
376_T392_K0.7180.52
352_E357_K0.7180.52
13_T40_V0.7180.52
520_A692_G0.7160.52
473_S504_D0.7160.52
676_V683_F0.7140.51
309_V398_I0.7140.51
519_F646_I0.7120.51
103_T248_S0.7120.51
204_K210_M0.7120.51
316_I355_K0.7100.51
596_A607_I0.7100.51
102_K256_Q0.7100.51
540_K642_D0.7080.51
570_T573_L0.7080.51
88_D93_L0.7050.50
452_G533_G0.7050.50
618_E650_T0.7040.50
110_D207_T0.7040.50
583_S614_P0.7030.50
181_K438_L0.7020.50
35_I155_N0.7010.50
221_T231_S0.7000.50
223_N227_A0.7000.50
560_L604_F0.6990.50
235_T420_L0.6990.50
613_P617_S0.6980.50
565_M658_H0.6980.50
64_I244_D0.6980.50
679_S682_R0.6970.50
520_A614_P0.6960.50
295_Q348_R0.6960.50
534_V664_M0.6940.49
31_R35_I0.6910.49
257_N375_L0.6900.49
541_T605_D0.6900.49
532_T597_K0.6900.49
273_A397_K0.6890.49
545_A572_E0.6890.49
42_A49_T0.6880.49
623_E711_Y0.6880.49
169_G445_L0.6880.49
111_I677_E0.6830.48
241_Q244_D0.6830.48
313_M317_D0.6830.48
97_R414_I0.6820.48
282_R317_D0.6810.48
218_L249_I0.6810.48
633_S639_V0.6800.48
236_G294_R0.6800.48
327_E333_L0.6800.48
335_T341_Y0.6790.48
419_V422_P0.6780.48
287_E661_T0.6770.48
646_I683_F0.6770.48
58_A243_R0.6760.48
48_Y543_V0.6750.47
615_N618_E0.6730.47
500_G694_I0.6710.47
100_L590_G0.6710.47
262_S267_K0.6700.47
320_L446_R0.6700.47
465_S632_A0.6690.47
675_E692_G0.6680.47
88_D227_A0.6680.47
75_D79_A0.6670.47
305_E620_L0.6670.47
42_A428_I0.6670.47
320_L355_K0.6660.47
126_D129_M0.6650.46
254_Q394_Q0.6650.46
582_L586_L0.6650.46
214_L245_I0.6650.46
519_F615_N0.6650.46
331_S337_V0.6640.46
519_F613_P0.6630.46
552_S555_N0.6630.46
540_K649_V0.6620.46
254_Q382_G0.6620.46
330_I337_V0.6610.46
393_E397_K0.6600.46
32_W556_K0.6600.46
159_N195_S0.6590.46
336_K341_Y0.6590.46
299_S565_M0.6590.46
95_R430_G0.6580.46
163_T424_K0.6580.46
258_I262_S0.6580.46
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205_Y213_Q0.6580.46
343_T346_E0.6570.46
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612_V628_L0.6560.46
369_Q663_L0.6560.46
141_F202_V0.6550.45
379_V391_N0.6550.45
592_I631_W0.6550.45
136_V296_D0.6540.45
349_Q557_R0.6530.45
613_P619_L0.6530.45
551_I565_M0.6520.45
568_G648_A0.6520.45
565_M613_P0.6520.45
507_I664_M0.6510.45
497_L506_A0.6510.45
354_E361_R0.6500.45
63_Q228_G0.6500.45
189_V323_L0.6500.45
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423_K427_I0.6480.45
178_Q188_M0.6480.45
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441_V445_L0.6470.45
396_L550_V0.6470.45
275_Q458_V0.6460.45
136_V190_E0.6460.45
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566_R616_P0.6450.44
171_S541_T0.6440.44
300_V365_M0.6440.44
38_T42_A0.6430.44
305_E310_L0.6430.44
446_R584_E0.6430.44
560_L640_L0.6420.44
41_F428_I0.6420.44
596_A635_N0.6410.44
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164_L174_G0.6320.43
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254_Q275_Q0.6260.43
516_S687_G0.6250.42
560_L636_Y0.6250.42
545_A574_L0.6230.42
315_N694_I0.6220.42
406_D554_T0.6220.42
227_A267_K0.6200.42
352_E356_A0.6200.42
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390_L393_E0.6170.42
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242_I403_T0.6160.42
668_Y699_F0.6160.42
647_L692_G0.6160.42
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155_N457_Q0.6150.41
62_V331_S0.6150.41
232_L293_F0.6150.41
140_T179_M0.6150.41
229_V305_E0.6140.41
250_A254_Q0.6140.41
438_L577_N0.6140.41
19_D34_V0.6130.41
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330_I334_Y0.6130.41
371_E639_V0.6120.41
81_A84_P0.6120.41
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15_S20_I0.6110.41
312_S315_N0.6110.41
304_L308_A0.6110.41
562_D612_V0.6110.41
67_N433_I0.6100.41
23_L445_L0.6100.41
65_E228_G0.6100.41
514_R615_N0.6100.41
66_Q219_T0.6100.41
44_C418_G0.6090.41
466_V671_N0.6090.41
686_N694_I0.6090.41
521_M529_L0.6090.41
437_M662_T0.6080.41
370_Q382_G0.6070.41
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435_G439_S0.6040.40
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367_K371_E0.6000.40
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101_G207_T0.5940.39
616_P619_L0.5940.39
290_L308_A0.5930.39
299_S306_A0.5920.39
411_D620_L0.5920.39
541_T642_D0.5910.39
173_R574_L0.5900.39
262_S392_K0.5900.39
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269_L365_M0.5880.39
48_Y410_V0.5880.39
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29_E451_R0.5870.39
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39_T68_S0.5700.37
258_I403_T0.5690.37
179_M560_L0.5690.37
279_V385_V0.5690.37
564_D645_P0.5680.37
567_K653_A0.5680.37
384_Q555_N0.5680.37
257_N407_V0.5670.37
26_T30_A0.5670.37
453_I602_A0.5670.37
505_L512_S0.5670.37
535_S648_A0.5670.37
285_V289_K0.5650.37
397_K400_E0.5640.37
517_L661_T0.5640.37
16_D23_L0.5630.36
234_Y448_L0.5630.36
33_W710_Y0.5630.36
104_V207_T0.5630.36
132_Q195_S0.5620.36
436_L440_I0.5620.36
40_V44_C0.5620.36
261_K362_V0.5610.36
566_R649_V0.5610.36
43_L593_T0.5600.36
531_M663_L0.5600.36
324_T331_S0.5590.36
301_D304_L0.5590.36
19_D671_N0.5590.36
592_I598_P0.5590.36
270_A523_Q0.5590.36
93_L459_L0.5590.36
329_E332_K0.5580.36
578_N609_R0.5580.36
424_K428_I0.5570.36
108_D137_K0.5560.36
471_P536_P0.5550.36
341_Y369_Q0.5550.36
51_F118_F0.5550.36
683_F691_K0.5540.36
348_R417_P0.5540.36
614_P649_V0.5530.36
156_V160_K0.5530.36
33_W560_L0.5520.35
45_A218_L0.5520.35
248_S635_N0.5520.35
415_T671_N0.5520.35
217_S627_E0.5510.35
164_L172_A0.5510.35
344_L471_P0.5510.35
155_N196_P0.5510.35
557_R597_K0.5500.35
608_P613_P0.5500.35
536_P555_N0.5500.35
24_V544_C0.5490.35
525_Q626_A0.5490.35
106_D453_I0.5490.35
275_Q397_K0.5480.35
647_L679_S0.5480.35
430_G448_L0.5480.35
31_R369_Q0.5470.35
324_T348_R0.5470.35
576_T608_P0.5470.35
319_Q328_A0.5470.35
289_K393_E0.5460.35
300_V306_A0.5440.35
402_S405_G0.5440.35
321_N324_T0.5430.35
569_Y572_E0.5430.35
444_L655_V0.5430.35
290_L707_D0.5420.35
350_A354_E0.5420.35
224_G317_D0.5420.35
375_L439_S0.5420.35
221_T425_G0.5410.34
501_N650_T0.5410.34
501_N646_I0.5410.34
413_A419_V0.5400.34
304_L409_I0.5400.34
173_R627_E0.5400.34
153_T163_T0.5390.34
112_A203_T0.5390.34
83_K241_Q0.5390.34
320_L408_R0.5390.34
25_G28_I0.5380.34
553_Q647_L0.5380.34
153_T165_S0.5380.34
432_I436_L0.5370.34
221_T440_I0.5370.34
192_I448_L0.5370.34
313_M318_A0.5360.34
462_H680_L0.5360.34
538_I697_S0.5350.34
453_I575_G0.5350.34
90_E271_F0.5340.34
104_V513_L0.5340.34
232_L628_L0.5340.34
35_I180_L0.5330.34
268_S385_V0.5330.34
519_F618_E0.5330.34
209_G602_A0.5320.34
508_E616_P0.5320.34
264_E384_Q0.5320.34
583_S613_P0.5320.34
82_N227_A0.5320.34
668_Y676_V0.5300.33
27_V644_P0.5300.33
565_M646_I0.5300.33
132_Q198_S0.5300.33
144_P198_S0.5290.33
176_A191_A0.5290.33
343_T547_L0.5290.33
562_D609_R0.5290.33
260_R650_T0.5290.33
165_S360_G0.5280.33
216_N557_R0.5280.33
138_V169_G0.5280.33
108_D301_D0.5260.33
642_D696_N0.5260.33
59_D231_S0.5260.33
248_S330_I0.5250.33
459_L462_H0.5250.33
221_T434_L0.5250.33
505_L582_L0.5250.33
456_P460_E0.5240.33
568_G609_R0.5240.33
230_L245_I0.5240.33
152_F164_L0.5230.33
74_Q78_S0.5230.33
671_N674_K0.5230.33
277_P396_L0.5220.33
290_L647_L0.5220.33
104_V621_M0.5220.33
394_Q469_S0.5220.33
216_N219_T0.5220.33
57_S453_I0.5210.33
644_P654_I0.5210.33
540_K566_R0.5210.33
59_D223_N0.5200.33
339_P346_E0.5200.33
339_P347_K0.5200.33
89_A99_V0.5190.32
376_T458_V0.5190.32
383_Q392_K0.5190.32
323_L347_K0.5190.32
225_K438_L0.5190.32
36_G220_V0.5180.32
579_V592_I0.5180.32
33_W36_G0.5180.32
33_W443_V0.5170.32
531_M643_T0.5170.32
244_D537_S0.5170.32
512_S574_L0.5170.32
525_Q561_I0.5160.32
317_D354_E0.5150.32
367_K383_Q0.5150.32
382_G385_V0.5150.32
449_F669_A0.5150.32
533_G540_K0.5150.32
459_L695_L0.5140.32
124_G127_R0.5140.32
457_Q695_L0.5140.32
34_V94_I0.5140.32
327_E330_I0.5140.32
331_S470_I0.5140.32
426_L430_G0.5140.32
436_L556_K0.5140.32
70_N78_S0.5140.32
290_L376_T0.5140.32
368_T382_G0.5140.32
191_A661_T0.5130.32
209_G418_G0.5120.32
229_V431_A0.5120.32
242_I415_T0.5120.32
45_A428_I0.5120.32
465_S667_R0.5120.32
540_K645_P0.5120.32
590_G624_R0.5110.32
272_L392_K0.5110.32
509_A562_D0.5110.32
140_T188_M0.5100.32
133_N195_S0.5100.32
640_L663_L0.5090.32
321_N329_E0.5090.32
123_A714_E0.5090.32
279_V389_L0.5090.32
276_L377_R0.5080.32
202_V455_S0.5080.32
139_T246_L0.5070.31
340_A431_A0.5060.31
578_N597_K0.5060.31
524_A588_G0.5060.31
151_V189_V0.5050.31
257_N406_D0.5050.31
156_V194_A0.5050.31
55_I596_A0.5050.31
103_T583_S0.5040.31
450_N676_V0.5040.31
64_I533_G0.5030.31
164_L594_T0.5030.31
410_V544_C0.5030.31
425_G429_L0.5020.31
187_L441_V0.5020.31
212_N418_G0.5020.31
239_R242_I0.5020.31
574_L686_N0.5020.31
557_R700_R0.5020.31
323_L344_L0.5010.31
507_I677_E0.5010.31
237_E577_N0.5000.31
680_L683_F0.5000.31
324_T327_E0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3la6A 4 0.3653 100 0.691 Contact Map
3cioA 2 0.3583 100 0.692 Contact Map
4jlvA 1 0.3153 100 0.716 Contact Map
4jmpA 1 0.3125 100 0.721 Contact Map
4wl1A 3 0.3028 100 0.828 Contact Map
4rz3A 2 0.2694 100 0.842 Contact Map
3fkqA 2 0.4333 100 0.845 Contact Map
3ug7A 4 0.2875 100 0.85 Contact Map
1g3qA 1 0.2694 100 0.854 Contact Map
1hyqA 1 0.2667 100 0.858 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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