GREMLIN Database
YOEA - Putative uncharacterized protein YoeA
UniProt: P76356 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14308
Length: 167 (143)
Sequences: 28498 (22196)
Seq/√Len: 1856.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_Q68_Q3.3221.00
139_R163_I2.9591.00
137_L162_F2.6531.00
70_S81_D2.4251.00
63_D66_T2.2951.00
61_V141_E2.2761.00
74_S77_D2.1211.00
82_I142_V2.0651.00
60_Q144_K2.0131.00
112_I117_V1.9931.00
112_I164_T1.9801.00
51_N54_E1.9721.00
133_D136_A1.9281.00
66_T69_N1.7641.00
111_L116_E1.7511.00
65_Q69_N1.6981.00
138_E165_K1.6731.00
22_I25_T1.6321.00
28_A31_S1.5801.00
64_Q165_K1.5581.00
38_E41_L1.5581.00
64_Q138_E1.5451.00
109_L116_E1.5431.00
99_R104_A1.5361.00
23_V26_A1.5261.00
27_T31_S1.5121.00
46_N50_S1.5071.00
38_E42_V1.4981.00
116_E154_Q1.4641.00
36_S39_E1.4501.00
141_E161_N1.4391.00
65_Q68_Q1.4381.00
77_D80_Q1.4341.00
20_S24_S1.4241.00
24_S27_T1.4111.00
20_S25_T1.3911.00
55_S59_I1.3761.00
110_I162_F1.3641.00
50_S54_E1.3601.00
113_D164_T1.3341.00
72_N78_N1.3001.00
100_I142_V1.2991.00
85_V100_I1.2951.00
37_N40_T1.2911.00
20_S23_V1.2811.00
21_G24_S1.2751.00
23_V27_T1.2731.00
73_A77_D1.2651.00
75_I162_F1.2621.00
67_L78_N1.2601.00
19_I22_I1.2531.00
142_V160_V1.2481.00
19_I23_V1.2461.00
29_T32_E1.2371.00
21_G25_T1.2121.00
138_E163_I1.1831.00
36_S41_L1.1811.00
61_V139_R1.1761.00
82_I85_V1.1761.00
59_I141_E1.1501.00
50_S53_W1.1471.00
26_A29_T1.1391.00
20_S26_A1.1381.00
138_E166_K1.1381.00
98_I160_V1.1131.00
52_L61_V1.1111.00
17_L20_S1.0981.00
37_N43_V1.0881.00
27_T30_S1.0701.00
60_Q82_I1.0681.00
19_I25_T1.0671.00
143_V147_Y1.0671.00
25_T28_A1.0641.00
109_L155_A1.0621.00
25_T29_T1.0571.00
50_S55_S1.0531.00
110_I160_V1.0471.00
66_T81_D1.0451.00
18_C21_G1.0381.00
44_T47_R1.0371.00
84_G144_K1.0341.00
18_C22_I1.0221.00
18_C24_S1.0211.00
66_T70_S1.0201.00
98_I110_I1.0201.00
34_K37_N1.0111.00
21_G27_T1.0111.00
24_S28_A1.0021.00
100_I158_G0.9851.00
99_R103_E0.9681.00
58_T144_K0.9671.00
21_G26_A0.9671.00
20_S27_T0.9651.00
75_I78_N0.9631.00
64_Q67_L0.9621.00
72_N77_D0.9581.00
151_Y159_I0.9551.00
37_N41_L0.9441.00
123_G132_I0.9341.00
62_I82_I0.9191.00
23_V28_A0.9131.00
87_I98_I0.8991.00
119_Y123_G0.8971.00
23_V29_T0.8971.00
33_T36_S0.8901.00
31_S34_K0.8901.00
83_P144_K0.8881.00
140_V162_F0.8831.00
25_T31_S0.8831.00
19_I24_S0.8801.00
85_V98_I0.8731.00
103_E107_R0.8721.00
114_G161_N0.8671.00
22_I26_A0.8671.00
118_T154_Q0.8601.00
111_L161_N0.8541.00
22_I28_A0.8431.00
17_L21_G0.8411.00
30_S33_T0.8371.00
36_S40_T0.8331.00
28_A32_E0.8231.00
119_Y122_A0.8171.00
52_L59_I0.8101.00
111_L159_I0.8061.00
39_E42_V0.8041.00
104_A107_R0.8041.00
139_R161_N0.7831.00
99_R107_R0.7811.00
26_A31_S0.7811.00
22_I27_T0.7711.00
38_E43_V0.7681.00
112_I132_I0.7651.00
89_D96_K0.7651.00
24_S29_T0.7551.00
26_A30_S0.7521.00
92_L95_R0.7391.00
97_Q107_R0.7331.00
72_N76_A0.7251.00
32_E35_I0.7241.00
60_Q83_P0.7241.00
33_T37_N0.7221.00
21_G28_A0.7131.00
78_N134_E0.7071.00
109_L154_Q0.7071.00
23_V30_S0.7011.00
24_S30_S0.6981.00
58_T101_R0.6881.00
17_L23_V0.6861.00
22_I29_T0.6811.00
72_N81_D0.6761.00
120_Q123_G0.6691.00
27_T32_E0.6671.00
18_C23_V0.6601.00
76_A96_K0.6601.00
100_I108_V0.6591.00
77_D96_K0.6441.00
22_I31_S0.6441.00
24_S31_S0.6431.00
20_S28_A0.6411.00
19_I27_T0.6361.00
103_E106_S0.6351.00
68_Q71_T0.6351.00
49_A55_S0.6291.00
20_S29_T0.6271.00
25_T30_S0.6251.00
107_R156_I0.6251.00
153_S156_I0.6221.00
17_L24_S0.6211.00
79_L85_V0.6131.00
37_N42_V0.6121.00
57_A145_G0.6071.00
111_L163_I0.6061.00
18_C25_T0.6031.00
90_N97_Q0.5981.00
100_I144_K0.5981.00
40_T43_V0.5971.00
56_P145_G0.5931.00
141_E163_I0.5931.00
134_E137_L0.5931.00
23_V31_S0.5911.00
35_I39_E0.5891.00
75_I140_V0.5891.00
118_T122_A0.5811.00
72_N134_E0.5801.00
132_I137_L0.5781.00
111_L151_Y0.5751.00
80_Q87_I0.5731.00
44_T49_A0.5651.00
26_A32_E0.5641.00
86_E99_R0.5621.00
107_R157_G0.5611.00
21_G29_T0.5601.00
35_I38_E0.5561.00
17_L26_A0.5531.00
34_K38_E0.5501.00
18_C26_A0.5471.00
19_I26_A0.5431.00
25_T32_E0.5411.00
35_I40_T0.5411.00
90_N95_R0.5391.00
108_V157_G0.5281.00
143_V159_I0.5271.00
78_N82_I0.5261.00
88_T97_Q0.5261.00
62_I78_N0.5201.00
91_S95_R0.5181.00
48_S51_N0.5171.00
86_E89_D0.5171.00
30_S34_K0.5151.00
17_L27_T0.5111.00
36_S43_V0.5101.00
88_T99_R0.5061.00
31_S35_I0.5001.00
143_V151_Y0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3fhhA 1 0.7605 100 0.178 Contact Map
2hdiA 1 0.7605 100 0.211 Contact Map
4epaA 1 0.6946 100 0.213 Contact Map
3v8xA 1 0.6766 100 0.219 Contact Map
4cu4A 1 0.8024 100 0.234 Contact Map
3cslA 1 0.6886 100 0.252 Contact Map
1fepA 1 0.7485 100 0.257 Contact Map
4b7oA 1 0.6826 100 0.265 Contact Map
2gufA 1 0.7665 100 0.265 Contact Map
1kmoA 1 0.7605 100 0.278 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0071 seconds.