YEEO - ECOLI - GREMLIN Contacts

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YEEO - Uncharacterized transporter YeeO

UniProt:	P76352	Sequences: MWFHFLQLRSALNISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKPVVSE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13383
Length:	495 (425)
Sequences:	17732 (13294)
Seq/√Len:	644.9

ECOLI - YEEO DINF MDTK
BACSU - YISQ YOEA YPNP NORM
HALSA - Q9HMS7 Q9HRF7 Q9HRF2 Q9HN79

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
111_D	114_R	4.714	1.00
173_A	235_Y	3.905	1.00
162_T	224_V	3.358	1.00
79_G	309_F	3.152	1.00
104_A	334_G	3.150	1.00
375_A	388_V	3.078	1.00
142_E	161_L	3.011	1.00
370_F	373_V	2.983	1.00
270_W	274_G	2.844	1.00
189_N	192_I	2.782	1.00
140_F	143_Q	2.713	1.00
142_E	146_D	2.689	1.00
341_Q	344_Q	2.681	1.00
203_L	236_I	2.538	1.00
99_T	122_S	2.530	1.00
166_L	224_V	2.528	1.00
266_F	270_W	2.495	1.00
210_I	215_L	2.429	1.00
66_L	212_I	2.404	1.00
73_D	155_E	2.388	1.00
161_L	165_E	2.347	1.00
153_T	302_T	2.306	1.00
66_L	209_G	2.306	1.00
417_D	469_R	2.280	1.00
106_S	114_R	2.271	1.00
77_G	159_L	2.251	1.00
40_R	44_P	2.217	1.00
200_L	237_G	2.168	1.00
176_I	238_A	2.114	1.00
196_I	240_A	2.098	1.00
159_L	162_T	2.080	1.00
350_R	354_W	2.063	1.00
382_P	386_H	2.035	1.00
166_L	227_G	2.021	1.00
329_S	352_V	2.014	1.00
71_G	74_A	1.988	1.00
117_V	265_N	1.977	1.00
307_G	387_V	1.972	1.00
447_G	450_G	1.966	1.00
63_S	230_L	1.960	1.00
390_I	449_V	1.950	1.00
224_V	228_L	1.946	1.00
371_A	393_W	1.929	1.00
67_V	226_A	1.921	1.00
50_F	324_A	1.918	1.00
158_A	162_T	1.914	1.00
170_S	231_T	1.902	1.00
212_I	226_A	1.889	1.00
221_L	228_L	1.865	1.00
210_I	214_G	1.841	1.00
126_M	179_I	1.839	1.00
383_Q	386_H	1.830	1.00
66_L	208_S	1.822	1.00
72_K	381_D	1.785	1.00
372_G	389_V	1.782	1.00
47_V	51_M	1.772	1.00
336_R	344_Q	1.764	1.00
303_S	383_Q	1.749	1.00
106_S	111_D	1.725	1.00
141_G	161_L	1.692	1.00
239_V	243_W	1.690	1.00
106_S	109_K	1.689	1.00
215_L	220_G	1.685	1.00
146_D	157_K	1.681	1.00
191_K	195_L	1.675	1.00
166_L	228_L	1.670	1.00
169_L	172_P	1.667	1.00
332_I	348_Q	1.663	1.00
337_L	415_A	1.662	1.00
371_A	389_V	1.661	1.00
401_I	460_A	1.660	1.00
214_G	220_G	1.656	1.00
196_I	241_I	1.648	1.00
173_A	238_A	1.628	1.00
368_A	393_W	1.628	1.00
265_N	268_I	1.617	1.00
46_A	328_A	1.612	1.00
202_I	206_I	1.594	1.00
349_L	408_L	1.587	1.00
356_S	403_S	1.584	1.00
102_V	118_A	1.582	1.00
209_G	215_L	1.573	1.00
347_I	350_R	1.568	1.00
209_G	213_Y	1.551	1.00
155_E	302_T	1.550	1.00
62_L	205_I	1.549	1.00
208_S	226_A	1.533	1.00
346_E	350_R	1.530	1.00
143_Q	146_D	1.529	1.00
157_K	161_L	1.516	1.00
337_L	345_A	1.503	1.00
155_E	158_A	1.500	1.00
207_I	229_G	1.473	1.00
166_L	231_T	1.471	1.00
372_G	376_S	1.467	1.00
141_G	165_E	1.466	1.00
134_A	172_P	1.466	1.00
364_A	368_A	1.465	1.00
211_L	215_L	1.458	1.00
347_I	351_H	1.455	1.00
146_D	154_T	1.455	1.00
203_L	207_I	1.454	1.00
39_W	351_H	1.453	1.00
81_A	164_L	1.439	1.00
417_D	420_Y	1.435	1.00
154_T	158_A	1.434	1.00
142_E	158_A	1.430	1.00
180_G	241_I	1.424	1.00
206_I	210_I	1.421	1.00
145_I	157_K	1.411	1.00
343_A	347_I	1.410	1.00
349_L	411_G	1.407	1.00
67_V	78_V	1.406	1.00
63_S	204_N	1.404	1.00
336_R	341_Q	1.400	1.00
373_V	376_S	1.386	1.00
446_W	450_G	1.377	1.00
206_I	209_G	1.374	1.00
106_S	118_A	1.368	1.00
38_F	332_I	1.357	1.00
394_L	453_M	1.357	1.00
112_R	116_R	1.351	1.00
243_W	247_I	1.351	1.00
373_V	377_F	1.348	1.00
376_S	385_K	1.347	1.00
211_L	221_L	1.341	1.00
36_V	40_R	1.337	1.00
467_Y	471_V	1.331	1.00
195_L	199_S	1.316	1.00
105_F	334_G	1.316	1.00
51_M	194_L	1.314	1.00
464_V	468_W	1.312	1.00
468_W	471_V	1.307	1.00
368_A	396_A	1.304	1.00
137_I	168_V	1.294	1.00
389_V	393_W	1.288	1.00
107_L	335_R	1.285	1.00
107_L	115_A	1.280	1.00
224_V	227_G	1.279	1.00
354_W	358_L	1.278	1.00
356_S	407_V	1.275	1.00
114_R	117_V	1.273	1.00
108_G	338_G	1.272	1.00
468_W	472_T	1.261	1.00
439_V	443_M	1.260	1.00
105_F	109_K	1.258	1.00
55_C	198_G	1.258	1.00
113_R	117_V	1.258	1.00
427_L	431_G	1.256	1.00
196_I	244_V	1.251	1.00
438_Y	442_I	1.251	1.00
142_E	157_K	1.247	1.00
74_A	159_L	1.245	1.00
386_H	390_I	1.244	1.00
143_Q	147_F	1.239	1.00
207_I	232_I	1.238	1.00
432_C	461_V	1.235	1.00
70_L	213_Y	1.226	1.00
267_S	270_W	1.224	1.00
64_T	313_S	1.220	1.00
73_D	302_T	1.217	1.00
365_W	369_P	1.212	1.00
76_A	306_A	1.210	1.00
314_I	374_M	1.209	1.00
419_R	423_W	1.202	1.00
149_A	152_A	1.199	1.00
39_W	355_L	1.198	1.00
208_S	229_G	1.198	1.00
114_R	268_I	1.195	1.00
342_I	346_E	1.193	1.00
375_A	385_K	1.192	1.00
72_K	303_S	1.189	1.00
420_Y	469_R	1.187	1.00
204_N	230_L	1.184	1.00
64_T	75_M	1.164	1.00
450_G	454_G	1.155	1.00
105_F	416_R	1.153	1.00
277_I	281_V	1.153	1.00
77_G	156_V	1.152	1.00
209_G	212_I	1.150	1.00
446_W	453_M	1.150	1.00
199_S	240_A	1.149	1.00
78_V	223_F	1.142	1.00
326_G	410_A	1.137	1.00
69_W	380_Q	1.136	1.00
138_H	165_E	1.132	1.00
121_Q	264_L	1.129	1.00
69_W	213_Y	1.122	1.00
211_L	232_I	1.121	1.00
145_I	160_A	1.119	1.00
264_L	269_I	1.113	1.00
209_G	214_G	1.109	1.00
121_Q	269_I	1.092	1.00
253_L	257_L	1.082	1.00
469_R	472_T	1.079	1.00
405_S	459_W	1.078	1.00
119_T	183_A	1.077	1.00
73_D	159_L	1.076	1.00
333_T	345_A	1.072	1.00
387_V	390_I	1.070	1.00
189_N	193_P	1.069	1.00
42_I	352_V	1.069	1.00
103_V	186_G	1.068	1.00
134_A	138_H	1.064	1.00
63_S	208_S	1.057	1.00
431_G	435_V	1.052	1.00
311_A	391_L	1.050	1.00
37_L	40_R	1.045	1.00
304_V	448_V	1.039	1.00
125_I	269_I	1.039	1.00
211_L	214_G	1.036	1.00
214_G	221_L	1.035	1.00
443_M	446_W	1.029	1.00
349_L	470_M	1.025	1.00
303_S	387_V	1.023	1.00
203_L	233_S	1.020	1.00
423_W	427_L	1.018	1.00
435_V	439_V	1.016	1.00
424_V	466_F	1.016	1.00
358_L	362_A	1.012	1.00
385_K	388_V	1.005	1.00
139_H	143_Q	1.004	1.00
192_I	244_V	1.003	1.00
43_T	47_V	0.998	1.00
198_G	202_I	0.997	1.00
440_L	446_W	0.989	1.00
108_G	339_V	0.987	1.00
126_M	175_A	0.984	1.00
228_L	231_T	0.982	1.00
165_E	169_L	0.980	1.00
351_H	355_L	0.977	1.00
188_G	335_R	0.977	1.00
386_H	389_V	0.972	1.00
215_L	221_L	0.971	1.00
127_T	176_I	0.970	1.00
295_M	299_G	0.967	1.00
118_A	268_I	0.967	1.00
122_S	272_V	0.965	1.00
117_V	268_I	0.957	1.00
134_A	169_L	0.954	1.00
116_R	259_S	0.954	1.00
256_S	259_S	0.946	1.00
314_I	367_T	0.945	1.00
458_D	462_R	0.943	1.00
60_G	82_D	0.943	1.00
139_H	165_E	0.940	1.00
107_L	187_A	0.938	1.00
271_E	274_G	0.936	1.00
105_F	337_L	0.934	1.00
324_A	328_A	0.928	1.00
394_L	449_V	0.925	1.00
251_P	254_R	0.925	1.00
180_G	238_A	0.925	1.00
361_T	365_W	0.923	1.00
208_S	230_L	0.922	1.00
336_R	348_Q	0.918	1.00
372_G	386_H	0.914	1.00
107_L	112_R	0.914	1.00
141_G	164_L	0.913	1.00
124_V	264_L	0.910	1.00
285_L	426_M	0.909	1.00
401_I	463_A	0.909	1.00
294_Q	298_A	0.904	1.00
35_K	341_Q	0.902	1.00
375_A	389_V	0.899	1.00
362_A	366_L	0.898	1.00
231_T	235_Y	0.897	1.00
184_L	245_L	0.893	1.00
391_L	448_V	0.892	1.00
301_G	304_V	0.890	1.00
80_L	152_A	0.888	1.00
128_L	132_L	0.886	1.00
307_G	384_V	0.886	1.00
41_E	44_P	0.885	1.00
408_L	470_M	0.883	1.00
310_I	378_Y	0.880	1.00
235_Y	239_V	0.877	1.00
207_I	211_L	0.875	1.00
49_I	327_S	0.873	1.00
92_F	175_A	0.871	1.00
412_F	469_R	0.871	1.00
345_A	349_L	0.869	1.00
62_L	204_N	0.867	1.00
353_F	404_A	0.866	1.00
298_A	305_I	0.864	1.00
189_N	244_V	0.861	1.00
362_A	365_W	0.855	1.00
385_K	389_V	0.852	1.00
65_F	68_S	0.852	1.00
70_L	220_G	0.852	1.00
162_T	165_E	0.851	1.00
436_V	457_A	0.850	1.00
333_T	414_G	0.849	1.00
296_F	437_G	0.846	1.00
66_L	213_Y	0.846	1.00
345_A	415_A	0.845	1.00
159_L	223_F	0.845	1.00
308_N	452_W	0.841	1.00
296_F	438_Y	0.838	1.00
368_A	372_G	0.837	1.00
55_C	201_N	0.837	1.00
76_A	156_V	0.836	1.00
62_L	201_N	0.836	1.00
383_Q	387_V	0.830	1.00
85_N	167_T	0.830	1.00
45_L	190_T	0.828	1.00
199_S	203_L	0.827	1.00
105_F	271_E	0.826	1.00
99_T	103_V	0.825	1.00
369_P	373_V	0.821	1.00
177_T	237_G	0.820	1.00
204_N	208_S	0.819	1.00
322_G	360_L	0.814	1.00
281_V	422_M	0.811	1.00
132_L	136_L	0.811	1.00
138_H	142_E	0.811	1.00
195_L	198_G	0.810	1.00
333_T	411_G	0.810	1.00
135_T	139_H	0.810	1.00
240_A	243_W	0.809	1.00
228_L	232_I	0.809	1.00
379_T	384_V	0.807	1.00
454_G	458_D	0.806	1.00
274_G	419_R	0.805	1.00
297_V	448_V	0.804	1.00
180_G	245_L	0.803	1.00
325_L	352_V	0.803	1.00
304_V	387_V	0.803	1.00
313_S	378_Y	0.802	1.00
194_L	198_G	0.801	1.00
236_I	240_A	0.798	1.00
307_G	388_V	0.797	1.00
169_L	231_T	0.794	1.00
154_T	157_K	0.794	1.00
449_V	453_M	0.792	1.00
336_R	339_V	0.790	1.00
189_N	248_G	0.788	1.00
136_L	140_F	0.787	1.00
72_K	384_V	0.782	1.00
103_V	183_A	0.778	1.00
432_C	435_V	0.778	1.00
296_F	299_G	0.778	1.00
254_R	257_L	0.778	1.00
428_S	462_R	0.775	1.00
347_I	354_W	0.773	1.00
91_F	280_S	0.771	1.00
73_D	76_A	0.771	1.00
404_A	463_A	0.771	1.00
156_V	305_I	0.769	1.00
149_A	153_T	0.768	1.00
382_P	385_K	0.767	1.00
184_L	241_I	0.767	1.00
67_V	212_I	0.766	1.00
166_L	169_L	0.766	1.00
73_D	156_V	0.765	1.00
41_E	335_R	0.764	1.00
257_L	260_Y	0.762	1.00
41_E	332_I	0.762	1.00
300_M	441_G	0.760	1.00
243_W	246_A	0.759	1.00
436_V	440_L	0.758	1.00
102_V	275_I	0.756	1.00
55_C	58_L	0.754	1.00
352_V	407_V	0.752	1.00
42_I	351_H	0.751	1.00
394_L	456_F	0.749	1.00
310_I	388_V	0.749	1.00
184_L	192_I	0.749	1.00
104_A	186_G	0.748	1.00
343_A	350_R	0.747	1.00
39_W	354_W	0.747	1.00
204_N	233_S	0.745	1.00
440_L	450_G	0.743	1.00
158_A	161_L	0.742	1.00
59_M	230_L	0.741	1.00
460_A	464_V	0.738	1.00
437_G	441_G	0.738	1.00
307_G	391_L	0.738	1.00
358_L	361_T	0.736	1.00
162_T	223_F	0.735	1.00
52_E	197_N	0.734	1.00
141_G	168_V	0.734	1.00
299_G	442_I	0.732	1.00
39_W	43_T	0.731	1.00
297_V	451_V	0.729	1.00
208_S	212_I	0.729	1.00
271_E	416_R	0.727	1.00
185_R	193_P	0.727	1.00
397_L	400_P	0.725	1.00
101_V	105_F	0.724	1.00
344_Q	347_I	0.724	1.00
109_K	338_G	0.723	1.00
77_G	223_F	0.719	1.00
122_S	179_I	0.718	1.00
357_T	361_T	0.717	1.00
124_V	128_L	0.717	1.00
46_A	324_A	0.714	1.00
351_H	354_W	0.713	1.00
361_T	400_P	0.712	1.00
220_G	224_V	0.711	1.00
61_V	317_L	0.711	1.00
102_V	106_S	0.711	1.00
268_I	271_E	0.710	1.00
242_L	246_A	0.708	1.00
58_L	62_L	0.707	1.00
68_S	75_M	0.707	1.00
325_L	359_G	0.706	1.00
441_G	450_G	0.705	1.00
132_L	135_T	0.701	1.00
432_C	436_V	0.701	1.00
371_A	392_I	0.700	1.00
62_L	66_L	0.700	1.00
203_L	232_I	0.699	1.00
296_F	441_G	0.697	1.00
227_G	231_T	0.694	1.00
336_R	345_A	0.692	1.00
42_I	328_A	0.691	1.00
381_D	385_K	0.691	1.00
155_E	159_L	0.689	1.00
232_I	235_Y	0.686	1.00
370_F	374_M	0.685	1.00
333_T	349_L	0.684	1.00
65_F	377_F	0.682	1.00
192_I	240_A	0.681	1.00
354_W	357_T	0.681	1.00
276_G	280_S	0.679	1.00
103_V	115_A	0.677	1.00
371_A	375_A	0.676	1.00
453_M	456_F	0.675	1.00
142_E	165_E	0.673	1.00
199_S	236_I	0.671	1.00
168_V	171_Y	0.671	1.00
145_I	164_L	0.668	1.00
325_L	356_S	0.668	1.00
292_L	434_V	0.667	1.00
163_Y	208_S	0.667	1.00
116_R	256_S	0.667	1.00
77_G	160_A	0.663	1.00
357_T	403_S	0.663	1.00
450_G	453_M	0.663	1.00
360_L	403_S	0.662	1.00
329_S	333_T	0.662	1.00
140_F	144_I	0.662	1.00
420_Y	424_V	0.661	1.00
293_T	451_V	0.661	1.00
67_V	223_F	0.660	1.00
372_G	385_K	0.659	1.00
130_A	172_P	0.658	1.00
410_A	414_G	0.656	1.00
114_R	118_A	0.649	1.00
368_A	371_A	0.648	1.00
284_V	288_S	0.646	1.00
164_L	168_V	0.644	1.00
170_S	173_A	0.644	1.00
252_A	255_I	0.644	1.00
152_A	298_A	0.642	1.00
120_R	260_Y	0.640	1.00
425_S	428_S	0.639	1.00
275_I	418_A	0.638	1.00
233_S	236_I	0.638	1.00
113_R	259_S	0.638	1.00
434_V	438_Y	0.637	1.00
169_L	173_A	0.637	1.00
278_P	422_M	0.637	1.00
296_F	442_I	0.636	1.00
369_P	372_G	0.636	1.00
67_V	74_A	0.634	1.00
65_F	69_W	0.633	1.00
135_T	138_H	0.632	1.00
307_G	452_W	0.631	1.00
94_A	280_S	0.629	1.00
359_G	363_I	0.625	1.00
70_L	74_A	0.625	1.00
59_M	200_L	0.625	1.00
221_L	224_V	0.623	1.00
213_Y	221_L	0.623	1.00
74_A	222_G	0.623	1.00
101_V	275_I	0.623	1.00
273_M	277_I	0.621	1.00
448_V	452_W	0.621	1.00
297_V	308_N	0.619	1.00
343_A	346_E	0.618	1.00
117_V	120_R	0.617	1.00
75_M	310_I	0.617	1.00
170_S	234_R	0.617	1.00
303_S	306_A	0.615	1.00
393_W	397_L	0.615	1.00
315_A	399_M	0.613	1.00
168_V	172_P	0.612	1.00
59_M	234_R	0.607	1.00
342_I	345_A	0.606	1.00
321_P	359_G	0.604	1.00
211_L	226_A	0.604	1.00
58_L	201_N	0.602	1.00
113_R	116_R	0.602	1.00
437_G	451_V	0.601	1.00
198_G	201_N	0.600	1.00
433_R	458_D	0.600	1.00
127_T	131_V	0.600	1.00
255_I	258_K	0.598	1.00
366_L	370_F	0.598	1.00
156_V	159_L	0.597	1.00
330_T	413_K	0.595	1.00
180_G	242_L	0.594	1.00
54_A	58_L	0.594	1.00
379_T	382_P	0.594	1.00
255_I	260_Y	0.594	1.00
240_A	244_V	0.593	1.00
117_V	121_Q	0.593	1.00
411_G	415_A	0.592	1.00
177_T	238_A	0.592	1.00
136_L	139_H	0.592	1.00
440_L	443_M	0.591	1.00
379_T	385_K	0.591	1.00
300_M	304_V	0.591	1.00
163_Y	226_A	0.589	1.00
296_F	451_V	0.589	1.00
157_K	160_A	0.587	1.00
204_N	229_G	0.587	1.00
165_E	224_V	0.587	1.00
337_L	342_I	0.585	1.00
318_I	363_I	0.583	1.00
181_S	185_R	0.580	1.00
41_E	344_Q	0.580	1.00
111_D	117_V	0.580	1.00
138_H	169_L	0.580	1.00
76_A	79_G	0.578	1.00
203_L	206_I	0.578	1.00
152_A	157_K	0.577	1.00
408_L	466_F	0.577	1.00
355_L	358_L	0.577	1.00
211_L	228_L	0.577	1.00
101_V	334_G	0.576	1.00
408_L	467_Y	0.575	1.00
357_T	400_P	0.574	1.00
38_F	351_H	0.574	1.00
319_N	402_W	0.574	1.00
120_R	259_S	0.573	1.00
412_F	417_D	0.572	1.00
131_V	135_T	0.572	1.00
335_R	339_V	0.571	1.00
424_V	465_L	0.570	1.00
42_I	355_L	0.570	1.00
138_H	141_G	0.568	1.00
109_K	340_G	0.568	1.00
199_S	202_I	0.567	1.00
384_V	388_V	0.566	1.00
396_A	400_P	0.565	1.00
277_I	280_S	0.564	1.00
436_V	439_V	0.563	1.00
145_I	161_L	0.563	1.00
353_F	357_T	0.563	1.00
418_A	422_M	0.562	1.00
357_T	404_A	0.560	1.00
130_A	168_V	0.560	1.00
131_V	134_A	0.558	1.00
100_T	182_G	0.558	1.00
465_L	468_W	0.557	1.00
74_A	77_G	0.557	1.00
315_A	395_N	0.554	1.00
162_T	166_L	0.554	1.00
60_G	167_T	0.552	1.00
254_R	260_Y	0.550	1.00
427_L	465_L	0.550	1.00
311_A	392_I	0.550	1.00
196_I	237_G	0.545	1.00
316_A	319_N	0.542	1.00
110_R	339_V	0.541	1.00
127_T	130_A	0.541	1.00
82_D	86_M	0.541	1.00
439_V	442_I	0.540	1.00
304_V	307_G	0.540	1.00
405_S	462_R	0.539	1.00
130_A	134_A	0.539	1.00
38_F	347_I	0.539	1.00
131_V	172_P	0.537	1.00
453_M	457_A	0.537	1.00
247_I	251_P	0.536	0.99
172_P	235_Y	0.535	0.99
322_G	403_S	0.535	0.99
300_M	447_G	0.535	0.99
97_L	327_S	0.535	0.99
156_V	302_T	0.535	0.99
49_I	324_A	0.534	0.99
438_Y	441_G	0.534	0.99
254_R	258_K	0.534	0.99
447_G	454_G	0.533	0.99
244_V	248_G	0.532	0.99
205_I	209_G	0.531	0.99
173_A	231_T	0.530	0.99
120_R	124_V	0.530	0.99
210_I	220_G	0.529	0.99
95_I	129_F	0.529	0.99
95_I	280_S	0.528	0.99
75_M	379_T	0.528	0.99
38_F	348_Q	0.528	0.99
72_K	306_A	0.527	0.99
428_S	465_L	0.527	0.99
364_A	400_P	0.526	0.99
436_V	461_V	0.525	0.99
156_V	160_A	0.521	0.99
182_G	185_R	0.519	0.99
229_G	233_S	0.519	0.99
435_V	438_Y	0.519	0.99
330_T	410_A	0.518	0.99
461_V	465_L	0.518	0.99
303_S	384_V	0.518	0.99
185_R	190_T	0.517	0.99
115_A	119_T	0.516	0.99
293_T	437_G	0.516	0.99
238_A	242_L	0.516	0.99
94_A	330_T	0.515	0.99
80_L	305_I	0.515	0.99
121_Q	268_I	0.514	0.99
37_L	41_E	0.514	0.99
62_L	65_F	0.514	0.99
253_L	256_S	0.513	0.99
66_L	229_G	0.513	0.99
353_F	408_L	0.511	0.99
80_L	160_A	0.511	0.99
283_S	287_T	0.510	0.99
192_I	248_G	0.510	0.99
404_A	467_Y	0.510	0.99
329_S	407_V	0.510	0.99
267_S	271_E	0.510	0.99
177_T	181_S	0.509	0.99
269_I	273_M	0.509	0.99
49_I	190_T	0.508	0.99
98_G	275_I	0.507	0.99
246_A	254_R	0.506	0.99
138_H	168_V	0.506	0.99
98_G	276_G	0.506	0.99
134_A	139_H	0.504	0.99
43_T	355_L	0.504	0.99
221_L	225_G	0.503	0.99
58_L	61_V	0.501	0.99
297_V	391_L	0.500	0.99
148_V	291_L	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mktA	1	0.9192	100	0.359	Contact Map
4humA	1	0.9273	100	0.371	Contact Map
4lz6A	1	0.897	100	0.394	Contact Map
3w4tA	1	0.8929	100	0.437	Contact Map
3wdoA	1	0.8121	85.2	0.946	Contact Map
4ikvA	1	0.8444	83.6	0.947	Contact Map
4zw9A	1	0.8444	78.8	0.95	Contact Map
1pw4A	1	0.8384	75.5	0.951	Contact Map
4j05A	3	0.796	75.4	0.951	Contact Map
4tphA	2	0.7576	68.2	0.954	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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