SHIA - ECOLI - GREMLIN Contacts

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SHIA - Shikimate transporter

UniProt:	P76350	Sequences: MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGITAALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKAFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGTLIGTLSAFPFFMALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVGGGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDSQRA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG20205
Length:	438 (377)
Sequences:	153921 (110993)
Seq/√Len:	5716.4

ECOLI - SHIA YHJE PROP KGTP YDJE ARAE UHPC NANT FUCP YJJL FSR UHPT RHMT YNFM NEPI YDJK GALP XYLE YEBQ MDFA YAAU BCR HSRA YGCS GLPT GUDP DGOT MHPT GARP EMRY ENTS EXUT MDTM YDFJ MDTG YJHB YAJR MDTD LPLT YIHN YQCE AMPG NARU SETC EMRB YDIN SOTB EMRD YDEE YDIM YGAY NARK YIHP YHHS YHJX YEAN NUPG SETA XAPB SETB MDTH YBJJ YDHP LACY MDTL TSGA YFCJ YDHC YCAD UIDB YIHO ARAJ CYNX YJIJ MELB YEGT YAGG YICJ HCAT
BACSU - YYBO ARAE YYAJ MMR TCRB YFIG YCNB GLPT YFNC GUDP YNCC YVKA CSBC YDEG NAIP YWFA YDGK LMRB YDDS IOLT YBFB YUBD YHCA YWOD YWTG YJBB YVMA YXLH EXUT IOLF YCXA YFIS YVQJ YFKL BMR2 YTBD YXAM YYBF YKUC YUSP YYCB YUXJ YITG YFHI YFMO YFMI GUTA YCEJ CSBX YWOG YHJO BMR1 YFKF NASA YJMB YOAB YQGE YQJV BBEX YBCL YDER BMR3 PBUE GLCP NARK YTTB YWBF YNAJ YFIU YXIO YCLF
HALSA - Q9HSM8 O54630 Q9HSK3 Q9HS33 Q9HRX5 Q9HPD6 Q9HN67 Q9HMQ8 Q9HMR5 Q9HSE5
SULSO - Q97YL8 Q97WR1 Q97U43 Q97U99 Q97VV2 Q97U80 Q97U98 Q7LX65 Q97Y43 Q97UY7 Q97VB7 Q97UD8 Q97VU3 Q97VB9 Q97YY8 Q97WS7 Q97Y11 Q980K3 Q97X63 Q97UR4 Q97X47 Q97U76 Q97VT2 Q97YH0 Q7LX71 Q97V89 Q97XW7 Q97WR9 Q97U91 Q97VC8 Q97WT1 Q97Y15 Q97ZC9 Q97Z36 Q97X02 Q97VQ5 Q97YG2 Q97X92 Q97VD1 Q97Z05 Q97Z07 Q97YI4 Q97UJ4 Q97WP8 Q97UK1 Q97U71 Q97WJ7 Q97YW8 Q97XG8 Q97UY6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
115_P	127_L	4.314	1.00
110_L	131_L	3.926	1.00
103_M	138_A	3.698	1.00
112_G	203_L	3.579	1.00
93_R	152_E	3.528	1.00
76_F	133_A	3.390	1.00
84_F	141_G	3.049	1.00
154_A	162_Y	3.031	1.00
100_T	141_G	2.898	1.00
105_G	209_V	2.850	1.00
107_A	131_L	2.810	1.00
325_I	356_A	2.656	1.00
158_K	161_F	2.625	1.00
89_D	378_Y	2.520	1.00
332_P	349_S	2.514	1.00
260_L	392_G	2.477	1.00
107_A	138_A	2.453	1.00
116_S	127_L	2.445	1.00
155_P	158_K	2.406	1.00
107_A	134_I	2.393	1.00
298_L	351_M	2.372	1.00
372_F	380_G	2.370	1.00
196_W	200_I	2.368	1.00
94_K	98_M	2.354	1.00
160_A	311_D	2.352	1.00
284_P	287_L	2.346	1.00
302_T	355_I	2.301	1.00
80_G	137_F	2.263	1.00
264_L	396_T	2.251	1.00
88_G	145_G	2.201	1.00
344_W	348_F	2.191	1.00
315_R	370_E	2.092	1.00
28_F	169_G	2.064	1.00
256_I	387_V	2.009	1.00
242_I	246_L	2.006	1.00
240_P	243_E	1.973	1.00
109_A	206_I	1.971	1.00
373_G	376_Y	1.960	1.00
114_L	127_L	1.951	1.00
92_G	95_R	1.932	1.00
314_G	317_R	1.855	1.00
308_W	312_R	1.843	1.00
416_I	420_A	1.828	1.00
72_V	133_A	1.824	1.00
72_V	129_V	1.804	1.00
111_I	131_L	1.792	1.00
107_A	135_Q	1.791	1.00
86_H	90_R	1.781	1.00
117_F	129_V	1.762	1.00
69_T	128_L	1.721	1.00
402_A	406_Y	1.699	1.00
268_I	400_A	1.692	1.00
243_E	246_L	1.684	1.00
114_L	131_L	1.681	1.00
65_A	117_F	1.680	1.00
54_F	65_A	1.662	1.00
98_M	216_R	1.651	1.00
76_F	80_G	1.648	1.00
413_S	416_I	1.618	1.00
54_F	117_F	1.597	1.00
317_R	320_I	1.589	1.00
161_F	311_D	1.584	1.00
203_L	207_V	1.583	1.00
283_L	287_L	1.578	1.00
344_W	347_F	1.574	1.00
112_G	206_I	1.565	1.00
47_L	50_N	1.564	1.00
118_S	130_T	1.557	1.00
243_E	376_Y	1.555	1.00
329_S	356_A	1.551	1.00
322_G	359_M	1.535	1.00
329_S	349_S	1.524	1.00
95_R	99_L	1.520	1.00
83_I	86_H	1.503	1.00
95_R	98_M	1.502	1.00
80_G	140_G	1.502	1.00
80_G	83_I	1.494	1.00
200_I	203_L	1.437	1.00
278_T	285_R	1.434	1.00
411_W	414_V	1.429	1.00
179_G	293_L	1.416	1.00
316_R	320_I	1.408	1.00
306_F	359_M	1.401	1.00
87_F	91_L	1.401	1.00
49_F	66_A	1.400	1.00
127_L	131_L	1.398	1.00
105_G	206_I	1.396	1.00
87_F	96_M	1.388	1.00
334_F	416_I	1.387	1.00
412_H	416_I	1.376	1.00
342_I	345_I	1.375	1.00
305_C	308_W	1.374	1.00
99_L	103_M	1.366	1.00
250_G	254_K	1.365	1.00
331_F	335_M	1.357	1.00
186_M	195_S	1.346	1.00
295_V	354_N	1.341	1.00
239_I	243_E	1.341	1.00
214_W	218_G	1.335	1.00
151_V	159_K	1.334	1.00
89_D	379_S	1.326	1.00
109_A	113_I	1.318	1.00
47_L	51_R	1.303	1.00
239_I	242_I	1.301	1.00
111_I	128_L	1.301	1.00
265_T	422_C	1.291	1.00
240_P	245_L	1.286	1.00
35_W	170_Y	1.284	1.00
91_L	95_R	1.282	1.00
225_F	229_Q	1.275	1.00
150_S	166_V	1.275	1.00
376_Y	379_S	1.271	1.00
317_R	321_T	1.271	1.00
240_P	244_A	1.268	1.00
302_T	305_C	1.265	1.00
287_L	290_N	1.264	1.00
267_Y	393_G	1.260	1.00
85_G	89_D	1.251	1.00
329_S	352_L	1.249	1.00
278_T	288_F	1.247	1.00
309_L	313_F	1.241	1.00
179_G	183_L	1.239	1.00
105_G	210_L	1.239	1.00
75_L	394_G	1.239	1.00
103_M	107_A	1.236	1.00
88_G	93_R	1.221	1.00
45_A	66_A	1.220	1.00
249_P	253_L	1.219	1.00
334_F	419_L	1.217	1.00
186_M	286_E	1.210	1.00
91_L	96_M	1.202	1.00
100_T	138_A	1.191	1.00
63_T	405_T	1.184	1.00
299_S	358_D	1.183	1.00
290_N	294_L	1.179	1.00
68_A	398_F	1.175	1.00
226_E	229_Q	1.173	1.00
277_S	283_L	1.165	1.00
156_K	159_K	1.157	1.00
104_M	138_A	1.150	1.00
49_F	54_F	1.148	1.00
343_F	347_F	1.147	1.00
238_R	241_V	1.146	1.00
308_W	311_D	1.139	1.00
197_G	200_I	1.134	1.00
73_G	136_G	1.125	1.00
298_L	302_T	1.122	1.00
30_G	142_E	1.118	1.00
92_G	96_M	1.116	1.00
252_F	256_I	1.115	1.00
414_V	418_L	1.112	1.00
238_R	242_I	1.112	1.00
110_L	113_I	1.109	1.00
321_T	325_I	1.104	1.00
253_L	257_A	1.104	1.00
226_E	230_H	1.099	1.00
307_A	311_D	1.098	1.00
242_I	245_L	1.096	1.00
327_T	426_A	1.091	1.00
327_T	331_F	1.085	1.00
403_L	407_F	1.083	1.00
241_V	245_L	1.083	1.00
76_F	136_G	1.077	1.00
320_I	426_A	1.072	1.00
301_L	304_P	1.071	1.00
276_Y	281_M	1.071	1.00
215_V	219_M	1.069	1.00
240_P	246_L	1.068	1.00
71_G	398_F	1.062	1.00
21_R	25_L	1.059	1.00
348_F	351_M	1.057	1.00
332_P	335_M	1.057	1.00
49_F	63_T	1.056	1.00
106_I	110_L	1.054	1.00
417_Y	421_G	1.053	1.00
118_S	127_L	1.050	1.00
93_R	148_L	1.050	1.00
64_L	68_A	1.048	1.00
215_V	218_G	1.048	1.00
237_K	240_P	1.044	1.00
144_G	147_A	1.029	1.00
420_A	424_I	1.025	1.00
259_R	384_G	1.025	1.00
184_I	200_I	1.025	1.00
236_K	240_P	1.024	1.00
71_G	394_G	1.021	1.00
78_P	386_Q	1.020	1.00
23_A	153_S	1.019	1.00
329_S	353_A	1.015	1.00
130_T	134_I	1.014	1.00
113_I	203_L	1.013	1.00
213_L	217_N	1.012	1.00
161_F	165_G	1.012	1.00
286_E	290_N	1.011	1.00
241_V	244_A	1.009	1.00
207_V	211_G	1.007	1.00
214_W	217_N	1.002	1.00
94_K	221_E	1.002	1.00
73_G	139_V	0.996	1.00
110_L	127_L	0.994	1.00
304_P	308_W	0.994	1.00
112_G	199_R	0.993	1.00
152_E	377_R	0.992	1.00
413_S	417_Y	0.992	1.00
72_V	76_F	0.990	1.00
127_L	130_T	0.987	1.00
161_F	308_W	0.986	1.00
392_G	396_T	0.980	1.00
217_N	220_E	0.979	1.00
68_A	72_V	0.975	1.00
324_L	328_L	0.973	1.00
423_L	427_M	0.971	1.00
183_L	195_S	0.970	1.00
65_A	129_V	0.966	1.00
95_R	221_E	0.964	1.00
239_I	245_L	0.964	1.00
236_K	239_I	0.960	1.00
36_Y	177_S	0.959	1.00
345_I	348_F	0.958	1.00
67_F	71_G	0.953	1.00
320_I	324_L	0.946	1.00
301_L	305_C	0.936	1.00
225_F	230_H	0.934	1.00
227_Q	230_H	0.928	1.00
44_T	185_S	0.927	1.00
99_L	102_W	0.919	1.00
326_G	422_C	0.916	1.00
225_F	228_Q	0.915	1.00
96_M	99_L	0.915	1.00
104_M	209_V	0.915	1.00
322_G	360_V	0.909	1.00
402_A	405_T	0.908	1.00
324_L	426_A	0.908	1.00
98_M	102_W	0.907	1.00
195_S	199_R	0.907	1.00
257_A	261_C	0.904	1.00
421_G	425_S	0.902	1.00
234_A	240_P	0.901	1.00
67_F	272_F	0.898	1.00
37_D	40_L	0.898	1.00
320_I	323_T	0.897	1.00
78_P	394_G	0.893	1.00
250_G	253_L	0.893	1.00
24_A	154_A	0.893	1.00
327_T	423_L	0.892	1.00
418_L	422_C	0.891	1.00
241_V	246_L	0.888	1.00
313_F	317_R	0.887	1.00
407_F	413_S	0.886	1.00
151_V	377_R	0.885	1.00
65_A	68_A	0.884	1.00
320_I	430_L	0.882	1.00
325_I	329_S	0.882	1.00
82_V	86_H	0.882	1.00
159_K	370_E	0.879	1.00
132_R	136_G	0.879	1.00
51_R	198_W	0.877	1.00
70_F	271_A	0.874	1.00
359_M	363_V	0.873	1.00
321_T	324_L	0.867	1.00
362_C	365_Q	0.865	1.00
258_L	429_A	0.862	1.00
297_G	301_L	0.859	1.00
348_F	352_L	0.854	1.00
366_P	370_E	0.854	1.00
149_L	153_S	0.852	1.00
81_G	385_Y	0.852	1.00
223_A	228_Q	0.851	1.00
368_F	384_G	0.850	1.00
323_T	425_S	0.849	1.00
374_A	377_R	0.845	1.00
330_A	334_F	0.844	1.00
115_P	118_S	0.837	1.00
44_T	201_P	0.837	1.00
327_T	422_C	0.835	1.00
291_I	347_F	0.830	1.00
313_F	318_V	0.828	1.00
336_A	349_S	0.826	1.00
176_L	179_G	0.826	1.00
262_E	360_V	0.825	1.00
369_T	381_A	0.825	1.00
30_G	97_L	0.825	1.00
92_G	221_E	0.820	1.00
401_A	405_T	0.819	1.00
239_I	246_L	0.819	1.00
329_S	332_P	0.819	1.00
65_A	69_T	0.817	1.00
415_A	419_L	0.816	1.00
276_Y	280_N	0.816	1.00
89_D	93_R	0.815	1.00
237_K	243_E	0.812	1.00
130_T	133_A	0.811	1.00
416_I	419_L	0.809	1.00
196_W	199_R	0.806	1.00
259_R	263_L	0.805	1.00
32_V	173_G	0.803	1.00
322_G	356_A	0.799	1.00
318_V	321_T	0.799	1.00
273_A	350_I	0.797	1.00
22_R	218_G	0.797	1.00
108_T	135_Q	0.797	1.00
216_R	220_E	0.796	1.00
40_L	201_P	0.796	1.00
64_L	398_F	0.796	1.00
108_T	206_I	0.792	1.00
175_L	297_G	0.791	1.00
263_L	388_A	0.789	1.00
324_L	327_T	0.789	1.00
36_Y	205_S	0.788	1.00
108_T	205_S	0.787	1.00
251_A	254_K	0.786	1.00
298_L	301_L	0.785	1.00
305_C	309_L	0.783	1.00
203_L	206_I	0.782	1.00
182_S	289_L	0.781	1.00
411_W	415_A	0.781	1.00
234_A	237_K	0.781	1.00
46_A	50_N	0.776	1.00
275_N	279_Q	0.773	1.00
111_I	135_Q	0.772	1.00
283_L	343_F	0.769	1.00
331_F	419_L	0.767	1.00
171_G	299_S	0.765	1.00
49_F	52_E	0.765	1.00
200_I	204_F	0.765	1.00
277_S	346_V	0.764	1.00
427_M	430_L	0.764	1.00
51_R	199_R	0.763	1.00
275_N	278_T	0.762	1.00
26_G	215_V	0.759	1.00
22_R	25_L	0.757	1.00
220_E	223_A	0.756	1.00
222_S	225_F	0.756	1.00
207_V	210_L	0.753	1.00
37_D	132_R	0.752	1.00
237_K	242_I	0.750	1.00
149_L	219_M	0.748	1.00
328_L	332_P	0.748	1.00
367_M	371_M	0.746	1.00
336_A	345_I	0.746	1.00
182_S	290_N	0.745	1.00
86_H	379_S	0.744	1.00
362_C	366_P	0.741	1.00
79_L	83_I	0.740	1.00
223_A	226_E	0.738	1.00
151_V	163_S	0.737	1.00
398_F	402_A	0.737	1.00
64_L	405_T	0.735	1.00
102_W	106_I	0.735	1.00
154_A	158_K	0.735	1.00
391_V	395_F	0.734	1.00
259_R	388_A	0.732	1.00
331_F	334_F	0.731	1.00
98_M	213_L	0.730	1.00
141_G	145_G	0.729	1.00
287_L	291_I	0.727	1.00
224_E	227_Q	0.724	1.00
157_N	161_F	0.724	1.00
115_P	199_R	0.722	1.00
68_A	129_V	0.719	1.00
80_G	84_F	0.719	1.00
226_E	231_Y	0.718	1.00
73_G	77_R	0.717	1.00
33_V	37_D	0.716	1.00
93_R	221_E	0.716	1.00
183_L	186_M	0.713	1.00
180_L	183_L	0.712	1.00
69_T	129_V	0.711	1.00
97_L	149_L	0.710	1.00
50_N	53_F	0.709	1.00
46_A	49_F	0.709	1.00
419_L	423_L	0.707	1.00
332_P	336_A	0.707	1.00
338_E	344_W	0.705	1.00
206_I	210_L	0.701	1.00
102_W	105_G	0.700	1.00
235_A	238_R	0.697	1.00
256_I	384_G	0.693	1.00
252_F	372_F	0.689	1.00
101_V	212_A	0.689	1.00
174_L	296_G	0.689	1.00
79_L	82_V	0.688	1.00
113_I	127_L	0.688	1.00
32_V	176_L	0.687	1.00
105_G	213_L	0.683	1.00
326_G	356_A	0.683	1.00
171_G	300_C	0.683	1.00
283_L	291_I	0.679	1.00
44_T	48_V	0.678	1.00
200_I	207_V	0.678	1.00
253_L	256_I	0.677	1.00
296_G	300_C	0.677	1.00
272_F	401_A	0.675	1.00
293_L	297_G	0.675	1.00
249_P	371_M	0.671	1.00
100_T	145_G	0.671	1.00
225_F	231_Y	0.670	1.00
414_V	417_Y	0.670	1.00
168_V	304_P	0.669	1.00
132_R	135_Q	0.665	1.00
345_I	349_S	0.665	1.00
417_Y	420_A	0.663	1.00
109_A	203_L	0.663	1.00
106_I	109_A	0.660	1.00
168_V	171_G	0.660	1.00
399_I	402_A	0.660	1.00
199_R	203_L	0.659	1.00
382_G	386_Q	0.656	1.00
48_V	198_W	0.655	1.00
204_F	207_V	0.655	1.00
310_A	363_V	0.654	1.00
151_V	369_T	0.652	1.00
77_R	389_S	0.651	1.00
163_S	366_P	0.650	1.00
111_I	202_F	0.646	1.00
302_T	306_F	0.645	1.00
251_A	371_M	0.645	1.00
84_F	140_G	0.644	1.00
326_G	329_S	0.643	1.00
256_I	383_V	0.642	1.00
168_V	300_C	0.640	1.00
277_S	281_M	0.637	1.00
294_L	347_F	0.635	1.00
185_S	201_P	0.634	1.00
147_A	166_V	0.634	1.00
255_I	384_G	0.633	1.00
183_L	290_N	0.633	1.00
98_M	217_N	0.629	1.00
347_F	351_M	0.628	1.00
78_P	389_S	0.625	1.00
361_V	365_Q	0.624	1.00
43_I	181_V	0.622	1.00
150_S	162_Y	0.622	1.00
144_G	148_L	0.622	1.00
386_Q	391_V	0.621	1.00
223_A	227_Q	0.620	1.00
320_I	429_A	0.617	1.00
287_L	343_F	0.615	1.00
257_A	260_L	0.614	1.00
74_F	393_G	0.614	1.00
114_L	117_F	0.612	1.00
305_C	355_I	0.611	1.00
235_A	245_L	0.611	1.00
268_I	418_L	0.610	1.00
249_P	376_Y	0.610	1.00
314_G	318_V	0.609	1.00
30_G	101_V	0.609	1.00
140_G	144_G	0.608	1.00
116_S	199_R	0.606	1.00
168_V	172_V	0.603	1.00
238_R	243_E	0.601	1.00
392_G	395_F	0.600	1.00
38_F	77_R	0.600	1.00
85_G	378_Y	0.599	1.00
277_S	291_I	0.598	1.00
383_V	387_V	0.597	1.00
148_L	378_Y	0.596	1.00
31_A	166_V	0.596	1.00
24_A	162_Y	0.595	1.00
163_S	369_T	0.594	1.00
212_A	216_R	0.594	1.00
368_F	371_M	0.592	1.00
23_A	26_G	0.591	1.00
294_L	351_M	0.591	1.00
41_Y	70_F	0.588	1.00
205_S	208_L	0.588	1.00
286_E	289_L	0.587	1.00
424_I	428_T	0.585	1.00
261_C	421_G	0.584	1.00
178_T	293_L	0.583	1.00
111_I	132_R	0.583	1.00
173_G	177_S	0.582	1.00
395_F	399_I	0.581	1.00
178_T	292_G	0.579	1.00
327_T	419_L	0.579	1.00
111_I	114_L	0.579	1.00
171_G	303_I	0.579	1.00
330_A	353_A	0.578	1.00
81_G	386_Q	0.578	1.00
64_L	67_F	0.577	1.00
306_F	309_L	0.577	1.00
369_T	377_R	0.575	1.00
243_E	375_S	0.573	1.00
422_C	426_A	0.570	1.00
377_R	381_A	0.570	1.00
404_I	407_F	0.570	1.00
43_I	47_L	0.569	1.00
182_S	186_M	0.568	1.00
256_I	260_L	0.568	1.00
277_S	288_F	0.566	1.00
159_K	369_T	0.563	1.00
37_D	104_M	0.562	1.00
104_M	139_V	0.561	1.00
47_L	185_S	0.560	1.00
39_L	174_L	0.560	1.00
73_G	132_R	0.559	1.00
105_G	109_A	0.559	1.00
158_K	162_Y	0.557	1.00
245_L	253_L	0.556	1.00
302_T	358_D	0.555	1.00
309_L	318_V	0.555	1.00
235_A	240_P	0.554	1.00
181_V	201_P	0.552	1.00
182_S	293_L	0.552	1.00
394_G	398_F	0.550	1.00
295_V	350_I	0.548	1.00
351_M	354_N	0.548	1.00
354_N	358_D	0.544	1.00
426_A	430_L	0.544	1.00
28_F	165_G	0.543	1.00
75_L	78_P	0.543	1.00
227_Q	231_Y	0.542	1.00
175_L	293_L	0.542	1.00
81_G	382_G	0.541	1.00
31_A	35_W	0.539	1.00
67_F	401_A	0.539	1.00
403_L	406_Y	0.539	1.00
309_L	312_R	0.538	1.00
37_D	205_S	0.537	1.00
104_M	142_E	0.537	1.00
291_I	294_L	0.537	1.00
88_G	96_M	0.532	1.00
265_T	268_I	0.531	1.00
29_A	33_V	0.530	1.00
412_H	415_A	0.529	1.00
366_P	369_T	0.528	1.00
335_M	416_I	0.528	1.00
294_L	297_G	0.526	1.00
54_F	66_A	0.526	1.00
234_A	241_V	0.521	1.00
290_N	293_L	0.521	1.00
98_M	101_V	0.520	1.00
263_L	267_Y	0.519	1.00
271_A	274_L	0.518	1.00
165_G	168_V	0.518	1.00
101_V	213_L	0.515	1.00
255_I	368_F	0.515	1.00
210_L	214_W	0.515	1.00
40_L	181_V	0.515	1.00
323_T	426_A	0.513	1.00
108_T	132_R	0.513	1.00
320_I	327_T	0.513	1.00
228_Q	231_Y	0.512	1.00
97_L	146_A	0.511	1.00
381_A	385_Y	0.511	1.00
261_C	425_S	0.511	1.00
169_G	173_G	0.511	1.00
131_L	135_Q	0.510	1.00
179_G	182_S	0.510	1.00
338_E	343_F	0.508	1.00
184_I	201_P	0.508	1.00
71_G	74_F	0.508	1.00
234_A	238_R	0.505	1.00
24_A	28_F	0.505	1.00
84_F	96_M	0.505	1.00
28_F	32_V	0.504	1.00
82_V	386_Q	0.504	1.00
211_G	214_W	0.504	1.00
272_F	275_N	0.503	1.00
21_R	24_A	0.503	1.00
63_T	404_I	0.503	1.00
69_T	117_F	0.502	1.00
425_S	429_A	0.502	1.00
132_R	143_W	0.501	1.00
294_L	298_L	0.501	1.00
84_F	87_F	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4j05A	3	0.8836	100	0.179	Contact Map
1pw4A	1	0.9132	100	0.19	Contact Map
3o7qA	1	0.895	100	0.209	Contact Map
4pypA	1	0.9018	100	0.224	Contact Map
3wdoA	1	0.8881	100	0.235	Contact Map
4zw9A	1	0.9247	100	0.251	Contact Map
2gfpA	2	0.8539	100	0.267	Contact Map
4gc0A	1	0.9429	100	0.272	Contact Map
2cfqA	1	0.9041	100	0.276	Contact Map
4ldsA	2	0.8836	100	0.282	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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