GREMLIN Database
YEDY - Sulfoxide reductase catalytic subunit YedY
UniProt: P76342 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14047
Length: 334 (283)
Sequences: 1467 (1023)
Seq/√Len: 60.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
121_A169_E5.7001.00
117_S257_K4.1801.00
165_L258_L4.1391.00
119_E171_T3.9961.00
15_E227_K3.7511.00
84_V224_V3.6501.00
144_M249_G3.6021.00
117_S255_S3.4271.00
121_A171_T3.3261.00
221_T240_I3.2611.00
284_Y313_L3.1791.00
127_D130_D3.1561.00
137_L222_V3.1181.00
173_N260_R2.8361.00
163_K166_A2.6711.00
162_H166_A2.6361.00
164_L220_M2.6301.00
115_K125_T2.5591.00
159_F164_L2.5581.00
134_R167_L2.5271.00
124_L168_A2.4601.00
160_P163_K2.4221.00
21_K24_Q2.3481.00
119_E260_R2.3441.00
119_E173_N2.3421.00
179_F256_I2.3101.00
166_A214_M2.2121.00
264_P268_N2.1981.00
178_A257_K2.1761.00
309_Q312_L2.1521.00
114_L237_V2.1081.00
90_F252_S2.0481.00
178_A264_P2.0131.00
115_K255_S1.9871.00
110_D128_H1.9221.00
294_T308_R1.9141.00
180_E255_S1.8991.00
25_V29_L1.8561.00
178_A268_N1.8531.00
81_A227_K1.8491.00
265_T268_N1.7931.00
126_L167_L1.7810.99
136_P163_K1.7650.99
120_V258_L1.7470.99
124_L167_L1.7440.99
120_V123_P1.7350.99
264_P269_L1.7090.99
101_A105_G1.7040.99
135_F159_F1.7030.99
200_L270_A1.6730.99
70_A73_Q1.6700.99
135_F167_L1.6610.99
122_K169_E1.6020.99
300_S309_Q1.5830.99
94_G100_P1.5510.99
69_P72_W1.5440.98
104_A107_L1.5430.98
65_E69_P1.5150.98
40_H43_H1.5060.98
29_L32_S1.4940.98
221_T239_L1.4900.98
318_A322_A1.4880.98
180_E257_K1.4760.98
38_L42_A1.4710.98
108_K184_A1.4700.98
154_V224_V1.4580.98
44_A48_S1.4240.97
299_G306_V1.4120.97
57_P60_A1.4020.97
205_V269_L1.4010.97
86_G101_A1.3870.97
155_P226_G1.3810.97
90_F154_V1.3760.97
128_H132_T1.3530.97
110_D129_D1.3470.96
94_G252_S1.3400.96
85_S230_P1.3280.96
76_L297_F1.3250.96
66_F69_P1.3040.96
165_L168_A1.2990.96
15_E20_M1.2950.96
116_I124_L1.2910.95
137_L157_I1.2820.95
139_E157_I1.2650.95
29_L33_A1.2610.95
116_I126_L1.2540.95
300_S306_V1.2390.94
297_F309_Q1.2330.94
239_L250_I1.2300.94
85_S233_N1.2200.94
24_Q27_K1.2030.93
149_A279_A1.1950.93
151_S297_F1.1890.93
39_P43_H1.1740.92
41_A44_A1.1680.92
221_T237_V1.1620.92
301_G306_V1.1600.92
177_V258_L1.1470.92
78_L224_V1.1460.92
301_G304_L1.1460.92
218_T241_V1.1450.92
163_K167_L1.1420.91
159_F222_V1.1390.91
165_L177_V1.1380.91
161_L213_A1.1250.91
30_G33_A1.1160.90
141_I153_V1.1150.90
70_A74_N1.1150.90
108_K111_P1.1140.90
159_F220_M1.1090.90
62_K69_P1.1050.90
299_G309_Q1.0870.89
69_P73_Q1.0730.89
149_A152_M1.0720.89
215_H318_A1.0610.88
105_G231_P1.0600.88
42_A45_D1.0570.88
300_S307_Q1.0570.88
31_I35_A1.0560.88
130_D133_R1.0430.87
33_A37_S1.0430.87
313_L318_A1.0270.86
276_G291_S1.0230.86
215_H218_T1.0190.86
101_A104_A1.0140.86
205_V250_I1.0140.86
73_Q78_L1.0140.86
132_T135_F1.0090.85
161_L239_L1.0080.85
216_P219_L1.0070.85
162_H216_P1.0050.85
164_L168_A1.0040.85
222_V237_V0.9960.85
28_A31_I0.9950.85
138_E219_L0.9840.84
210_L258_L0.9820.84
122_K168_A0.9750.83
157_I222_V0.9620.83
20_M27_K0.9600.82
80_P84_V0.9560.82
104_A109_T0.9550.82
139_E155_P0.9510.82
38_L41_A0.9490.82
76_L309_Q0.9480.82
113_T125_T0.9430.81
299_G307_Q0.9280.80
220_M237_V0.9230.80
56_P59_P0.9210.80
85_S224_V0.9190.80
25_V28_A0.9110.79
241_V249_G0.9040.78
116_I120_V0.8970.78
63_A67_S0.8910.77
215_H320_Q0.8910.77
262_R268_N0.8890.77
176_Y207_G0.8890.77
69_P75_N0.8880.77
64_L67_S0.8840.77
84_V141_I0.8800.77
28_A32_S0.8800.77
178_A269_L0.8790.76
32_S36_L0.8780.76
161_L256_I0.8760.76
116_I168_A0.8740.76
28_A35_A0.8720.76
76_L79_T0.8630.75
294_T301_G0.8560.75
79_T84_V0.8550.74
301_G307_Q0.8550.74
299_G308_R0.8510.74
72_W75_N0.8490.74
206_E247_F0.8480.74
121_A172_S0.8440.73
165_L214_M0.8430.73
74_N78_L0.8420.73
126_L168_A0.8360.73
73_Q76_L0.8320.72
104_A182_I0.8320.72
120_V168_A0.8280.72
257_K260_R0.8270.72
35_A38_L0.8260.72
222_V228_A0.8240.72
119_E210_L0.8220.71
78_L84_V0.8220.71
157_I223_G0.8220.71
125_T131_L0.8210.71
149_A300_S0.8200.71
124_L130_D0.8140.71
17_V20_M0.8130.71
81_A85_S0.8110.70
37_S41_A0.8080.70
34_T38_L0.7990.69
307_Q310_P0.7950.69
148_E151_S0.7940.69
120_V124_L0.7890.68
208_L241_V0.7870.68
141_I155_P0.7870.68
92_E232_Q0.7870.68
78_L81_A0.7800.67
26_L29_L0.7790.67
35_A39_P0.7790.67
64_L68_K0.7740.67
261_E264_P0.7730.67
206_E248_K0.7730.67
130_D134_R0.7650.66
100_P105_G0.7630.66
64_L69_P0.7620.66
110_D132_T0.7540.65
18_F224_V0.7500.64
36_L39_P0.7430.64
259_T265_T0.7410.63
39_P44_A0.7390.63
168_A258_L0.7380.63
61_G64_L0.7350.63
112_W218_T0.7350.63
72_W144_M0.7340.63
107_L182_I0.7300.62
82_D86_G0.7300.62
31_I37_S0.7270.62
45_D49_W0.7260.62
44_A47_L0.7260.62
220_M253_I0.7240.62
113_T128_H0.7220.61
87_Y154_V0.7200.61
58_A61_G0.7200.61
298_I306_V0.7140.61
15_E81_A0.7120.60
181_T250_I0.7110.60
34_T42_A0.7110.60
109_T128_H0.7110.60
131_L237_V0.7100.60
33_A181_T0.7080.60
172_S210_L0.7080.60
161_L214_M0.7060.60
42_A46_L0.7050.60
178_A205_V0.7040.60
90_F267_W0.7020.59
57_P63_A0.7010.59
223_G283_P0.7000.59
16_S33_A0.6970.59
301_G305_D0.6960.59
45_D48_S0.6940.58
144_M154_V0.6890.58
31_I34_T0.6890.58
33_A36_L0.6870.58
25_V30_G0.6870.58
119_E259_T0.6860.58
30_G41_A0.6850.57
179_F204_Y0.6850.57
283_P292_Q0.6830.57
43_H46_L0.6820.57
168_A173_N0.6800.57
100_P104_A0.6790.57
126_L169_E0.6780.57
110_D127_D0.6770.57
117_S178_A0.6750.56
71_A74_N0.6680.56
20_M28_A0.6630.55
100_P103_N0.6620.55
100_P201_K0.6610.55
160_P219_L0.6610.55
312_L318_A0.6600.55
165_L170_P0.6590.55
34_T37_S0.6590.55
42_A47_L0.6580.54
154_V297_F0.6560.54
26_L50_F0.6550.54
48_S51_K0.6550.54
300_S304_L0.6540.54
41_A46_L0.6540.54
50_F68_K0.6510.54
38_L48_S0.6480.53
276_G289_R0.6480.53
90_F156_W0.6470.53
72_W76_L0.6470.53
180_E205_V0.6460.53
121_A177_V0.6450.53
39_P46_L0.6450.53
176_Y263_P0.6440.53
182_I254_V0.6430.53
154_V225_Y0.6420.53
289_R292_Q0.6420.53
116_I122_K0.6410.52
300_S308_R0.6410.52
134_R163_K0.6410.52
124_L134_R0.6400.52
297_F300_S0.6380.52
151_S154_V0.6350.52
35_A43_H0.6350.52
85_S297_F0.6320.51
301_G309_Q0.6310.51
162_H168_A0.6310.51
27_K31_I0.6250.51
120_V210_L0.6230.50
145_R206_E0.6220.50
177_V213_A0.6210.50
228_A300_S0.6190.50
132_T228_A0.6170.50
283_P290_W0.6160.50
219_L240_I0.6140.49
221_T233_N0.6140.49
56_P60_A0.6130.49
47_L50_F0.6120.49
159_F219_L0.6110.49
57_P69_P0.6100.49
205_V264_P0.6090.49
41_A45_D0.6050.48
90_F152_M0.6020.48
127_D132_T0.5990.48
277_F280_N0.5980.48
39_P42_A0.5980.48
15_E221_T0.5970.48
24_Q28_A0.5960.47
31_I51_K0.5920.47
180_E250_I0.5920.47
159_F237_V0.5910.47
28_A38_L0.5890.47
37_S47_L0.5870.46
42_A49_W0.5840.46
131_L222_V0.5840.46
140_R217_L0.5830.46
160_P320_Q0.5830.46
76_L80_P0.5820.46
313_L320_Q0.5820.46
26_L42_A0.5810.46
224_V230_P0.5740.45
46_L49_W0.5730.45
217_L226_G0.5720.45
199_G202_Y0.5710.45
112_W128_H0.5700.44
181_T252_S0.5690.44
175_K260_R0.5690.44
30_G39_P0.5670.44
21_K27_K0.5670.44
115_K119_E0.5660.44
124_L128_H0.5640.44
139_E226_G0.5620.44
283_P287_H0.5600.43
70_A75_N0.5600.43
157_I160_P0.5570.43
292_Q295_E0.5570.43
284_Y318_A0.5560.43
306_V309_Q0.5550.43
115_K257_K0.5550.43
217_L242_P0.5540.43
284_Y310_P0.5540.43
280_N289_R0.5530.43
48_S52_G0.5530.43
117_S210_L0.5530.43
60_A63_A0.5520.42
150_W204_Y0.5510.42
81_A86_G0.5510.42
32_S35_A0.5510.42
37_S45_D0.5490.42
21_K25_V0.5490.42
245_Y267_W0.5490.42
41_A47_L0.5490.42
136_P160_P0.5480.42
116_I129_D0.5450.42
63_A69_P0.5450.42
41_A133_R0.5410.41
244_K252_S0.5410.41
95_L105_G0.5400.41
26_L205_V0.5400.41
283_P289_R0.5400.41
140_R223_G0.5390.41
212_E244_K0.5390.41
33_A38_L0.5390.41
21_K166_A0.5370.41
299_G305_D0.5360.41
40_H44_A0.5350.41
38_L45_D0.5350.41
26_L90_F0.5350.41
49_W116_I0.5330.40
246_G287_H0.5330.40
32_S68_K0.5330.40
102_A105_G0.5330.40
239_L256_I0.5310.40
218_T239_L0.5310.40
37_S40_H0.5300.40
62_K67_S0.5290.40
39_P49_W0.5270.40
145_R248_K0.5270.40
143_R153_V0.5250.40
93_F107_L0.5240.39
126_L134_R0.5240.39
247_F267_W0.5240.39
45_D163_K0.5240.39
110_D113_T0.5230.39
95_L270_A0.5220.39
107_L231_P0.5220.39
122_K210_L0.5220.39
159_F250_I0.5210.39
121_A258_L0.5200.39
224_V298_I0.5190.39
285_V288_P0.5190.39
130_D164_L0.5190.39
121_A173_N0.5190.39
93_F145_R0.5160.39
66_F70_A0.5150.38
24_Q29_L0.5150.38
44_A49_W0.5140.38
112_W254_V0.5140.38
67_S73_Q0.5130.38
304_L307_Q0.5130.38
64_L71_A0.5100.38
165_L210_L0.5090.38
248_K267_W0.5090.38
68_K74_N0.5070.38
160_P246_G0.5070.38
30_G34_T0.5070.38
140_R207_G0.5060.38
32_S86_G0.5050.37
92_E142_Y0.5040.37
41_A48_S0.5040.37
34_T172_S0.5030.37
170_P175_K0.5030.37
49_W163_K0.5030.37
47_L51_K0.5030.37
113_T127_D0.5010.37
73_Q318_A0.5010.37
20_M36_L0.5000.37
120_V170_P0.5000.37
74_N141_I0.5000.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xdyA 3 0.7904 100 0.346 Contact Map
2a9dA 2 0.7874 100 0.382 Contact Map
1ogpA 4 0.8084 100 0.388 Contact Map
2blfA 1 0.8263 100 0.392 Contact Map
1soxA 2 0.9162 100 0.393 Contact Map
2biiA 2 0.7335 100 0.412 Contact Map
2bihA 2 0.8443 100 0.413 Contact Map
4pw3A 2 0.7725 100 0.419 Contact Map
2xtsA 2 0.8323 100 0.453 Contact Map
2pq4B 1 0.1048 85.3 0.955 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.