GREMLIN Database
YEDW - Probable transcriptional regulatory protein YedW
UniProt: P76340 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14045
Length: 223 (203)
Sequences: 79000 (56428)
Seq/√Len: 3960.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
13_Q29_A3.8511.00
13_Q31_S3.4201.00
17_T29_A3.3951.00
6_I36_G2.8751.00
37_L65_T2.8401.00
34_R56_G2.6111.00
28_D45_Y2.5701.00
33_G57_M2.4901.00
41_L69_A2.4311.00
57_M65_T2.4101.00
32_D56_G2.3411.00
28_D39_L2.1311.00
19_G104_F2.1201.00
30_V39_L2.1011.00
17_T21_S2.0471.00
28_D43_D2.0341.00
53_M80_R2.0011.00
2_K26_V1.9961.00
23_A108_L1.9681.00
50_L62_I1.9511.00
63_L74_V1.9091.00
31_S35_D1.9041.00
86_R106_E1.8781.00
186_N189_D1.8491.00
65_T69_A1.7931.00
76_C89_G1.7931.00
32_D35_D1.7851.00
67_R95_N1.7281.00
76_C94_A1.7131.00
4_L30_V1.7071.00
39_L43_D1.6841.00
151_K154_Q1.6691.00
64_Q92_S1.6631.00
2_K28_D1.6401.00
57_M61_Q1.6371.00
83_V103_S1.6201.00
58_D61_Q1.6121.00
33_G62_I1.6071.00
96_D110_R1.6031.00
169_R189_D1.5741.00
158_L175_E1.5681.00
157_W161_S1.5611.00
40_A66_L1.5391.00
39_L42_K1.5211.00
65_T68_T1.5151.00
80_R85_D1.4761.00
129_G142_D1.4751.00
34_R57_M1.4551.00
48_I72_T1.4461.00
20_L111_V1.4421.00
167_I175_E1.4311.00
63_L76_C1.4291.00
191_A194_R1.4001.00
47_L111_V1.3821.00
168_P171_V1.3741.00
95_N117_Q1.3701.00
37_L62_I1.3611.00
61_Q64_Q1.3351.00
52_I60_W1.3241.00
10_Q31_S1.3181.00
39_L45_Y1.3031.00
75_I114_Q1.3001.00
37_L57_M1.2811.00
95_N114_Q1.2781.00
7_E13_Q1.2591.00
6_I54_L1.2531.00
60_W89_G1.2391.00
108_L112_R1.2261.00
38_Y42_K1.2231.00
52_I76_C1.2031.00
50_L63_L1.1991.00
192_I196_R1.1981.00
8_D51_D1.1951.00
25_Y112_R1.1901.00
35_D39_L1.1891.00
30_V36_G1.1851.00
60_W88_R1.1711.00
88_R92_S1.1641.00
35_D38_Y1.1571.00
4_L45_Y1.1551.00
82_S85_D1.1471.00
171_V175_E1.1441.00
34_R38_Y1.1381.00
152_E198_K1.1301.00
4_L36_G1.0941.00
4_L39_L1.0911.00
83_V87_V1.0831.00
24_G112_R1.0771.00
133_D136_S1.0741.00
37_L41_L1.0731.00
109_A113_A1.0731.00
36_G62_I1.0671.00
87_V91_D1.0611.00
153_F157_W1.0511.00
47_L115_L1.0501.00
154_Q157_W1.0481.00
64_Q88_R1.0471.00
2_K43_D1.0441.00
14_E29_A1.0411.00
158_L167_I1.0401.00
190_V193_R1.0311.00
187_T191_A1.0311.00
5_L16_V1.0291.00
91_D112_R1.0271.00
106_E109_A1.0251.00
3_I25_Y1.0191.00
201_D210_T1.0171.00
30_V35_D1.0131.00
170_T185_T1.0081.00
84_D88_R1.0071.00
23_A112_R0.9851.00
167_I171_V0.9831.00
131_R140_S0.9811.00
86_R99_V0.9731.00
138_S145_S0.9721.00
36_G40_A0.9711.00
10_Q14_E0.9601.00
48_I66_L0.9541.00
186_N190_V0.9491.00
4_L28_D0.9441.00
48_I74_V0.9401.00
52_I58_D0.9401.00
11_R15_W0.9391.00
83_V86_R0.9351.00
73_P95_N0.9311.00
150_R154_Q0.9311.00
38_Y41_L0.9181.00
63_L92_S0.9171.00
132_M160_A0.9141.00
60_W92_S0.9131.00
134_S157_W0.9101.00
63_L94_A0.9101.00
6_I30_V0.9091.00
50_L74_V0.9061.00
14_E17_T0.8951.00
16_V77_L0.8851.00
4_L40_A0.8791.00
50_L76_C0.8741.00
88_R91_D0.8701.00
61_Q65_T0.8691.00
49_I107_L0.8671.00
75_I110_R0.8661.00
6_I48_I0.8641.00
132_M153_F0.8571.00
18_Q22_E0.8541.00
81_D99_V0.8531.00
106_E110_R0.8461.00
185_T189_D0.8411.00
104_F108_L0.8411.00
73_P121_L0.8401.00
52_I85_D0.8311.00
62_I66_L0.8271.00
140_S145_S0.8261.00
155_L159_L0.8261.00
25_Y108_L0.8221.00
114_Q117_Q0.8211.00
10_Q13_Q0.8161.00
40_A72_T0.7951.00
85_D88_R0.7891.00
52_I80_R0.7881.00
54_L62_I0.7861.00
186_N193_R0.7801.00
126_E131_R0.7781.00
96_D113_A0.7771.00
40_A45_Y0.7741.00
64_Q68_T0.7681.00
57_M62_I0.7631.00
87_V105_S0.7621.00
103_S106_E0.7621.00
73_P117_Q0.7601.00
66_L74_V0.7581.00
113_A116_R0.7511.00
158_L172_I0.7491.00
171_V174_S0.7471.00
17_T27_I0.7461.00
33_G37_L0.7461.00
149_T152_E0.7441.00
194_R197_A0.7411.00
102_F107_L0.7391.00
77_L102_F0.7371.00
14_E18_Q0.7361.00
201_D204_P0.7351.00
170_T174_S0.7341.00
12_T102_F0.7321.00
6_I62_I0.7311.00
49_I77_L0.7251.00
115_L118_H0.7251.00
16_V107_L0.7221.00
84_D105_S0.7191.00
53_M79_A0.7161.00
193_R197_A0.7071.00
33_G56_G0.7031.00
37_L40_A0.7011.00
66_L70_K0.6981.00
149_T198_K0.6931.00
200_D206_K0.6921.00
15_W19_G0.6881.00
140_S143_N0.6871.00
49_I111_V0.6841.00
40_A48_I0.6831.00
158_L161_S0.6801.00
33_G54_L0.6791.00
113_A118_H0.6791.00
90_L110_R0.6791.00
205_E208_I0.6751.00
71_Q121_L0.6741.00
67_R73_P0.6731.00
129_G141_R0.6711.00
148_L152_E0.6691.00
7_E54_L0.6671.00
190_V194_R0.6631.00
37_L69_A0.6591.00
203_F206_K0.6571.00
124_T131_R0.6571.00
105_S109_A0.6571.00
5_L29_A0.6541.00
19_G108_L0.6541.00
41_L65_T0.6511.00
2_K46_A0.6491.00
9_N12_T0.6461.00
89_G94_A0.6451.00
110_R114_Q0.6441.00
206_K209_A0.6401.00
5_L17_T0.6361.00
187_T192_I0.6351.00
204_P207_L0.6351.00
49_I75_I0.6331.00
13_Q17_T0.6331.00
184_D187_T0.6301.00
137_H154_Q0.6281.00
75_I96_D0.6281.00
102_F106_E0.6271.00
63_L67_R0.6251.00
129_G133_D0.6211.00
91_D109_A0.6181.00
73_P115_L0.6181.00
109_A112_R0.6181.00
112_R116_R0.6171.00
154_Q158_L0.6161.00
84_D87_V0.6151.00
86_R103_S0.6141.00
132_M139_V0.6131.00
169_R185_T0.6081.00
52_I89_G0.6071.00
152_E155_L0.6041.00
127_I130_L0.6021.00
12_T15_W0.6021.00
188_V192_I0.6001.00
9_N79_A0.6001.00
60_W85_D0.5961.00
132_M157_W0.5951.00
118_H122_N0.5941.00
73_P118_H0.5921.00
141_R144_I0.5911.00
67_R72_T0.5891.00
50_L54_L0.5881.00
117_Q121_L0.5871.00
83_V105_S0.5871.00
161_S175_E0.5861.00
161_S167_I0.5781.00
152_E159_L0.5751.00
183_S188_V0.5751.00
51_D100_K0.5741.00
201_D206_K0.5741.00
137_H153_F0.5711.00
156_L159_L0.5691.00
189_D192_I0.5621.00
202_P205_E0.5571.00
19_G23_A0.5551.00
5_L27_I0.5531.00
201_D205_E0.5531.00
66_L72_T0.5471.00
8_D78_T0.5471.00
40_A69_A0.5451.00
5_L13_Q0.5441.00
20_L25_Y0.5441.00
183_S187_T0.5431.00
3_I47_L0.5421.00
130_L141_R0.5401.00
196_R201_D0.5401.00
159_L192_I0.5391.00
110_R113_A0.5371.00
78_T86_R0.5361.00
25_Y115_L0.5351.00
40_A62_I0.5341.00
71_Q120_A0.5311.00
78_T100_K0.5301.00
202_P206_K0.5271.00
35_D56_G0.5241.00
50_L66_L0.5161.00
192_I204_P0.5111.00
21_S26_V0.5111.00
197_A200_D0.5101.00
79_A101_P0.5101.00
40_A70_K0.5081.00
134_S137_H0.5061.00
116_R120_A0.5031.00
133_D138_S0.5031.00
127_I131_R0.5021.00
188_V191_A0.5021.00
151_K191_A0.5011.00
32_D54_L0.5011.00
209_A212_R0.5011.00
44_D70_K0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ys7A 2 0.9865 100 0.203 Contact Map
3r0jA 2 0.9641 100 0.205 Contact Map
2gwrA 1 0.9821 100 0.209 Contact Map
1kgsA 1 0.9686 100 0.217 Contact Map
4b09A 2 0.9417 100 0.218 Contact Map
2oqrA 2 0.9821 100 0.221 Contact Map
4kfcA 2 0.9821 100 0.224 Contact Map
2hqrA 2 0.9731 100 0.235 Contact Map
3q9sA 1 0.9372 100 0.245 Contact Map
1p2fA 1 0.9552 100 0.253 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0096 seconds.