YEDV - ECOLI - GREMLIN Contacts

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YEDV - Probable sensor-like histidine kinase YedV

UniProt:	P76339	Sequences: MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDSINKIVNRTNVSDGMLNNIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKINSIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICFKVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRITLPQRN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14044
Length:	452 (435)
Sequences:	47343 (40674)
Seq/√Len:	1950.2

ECOLI - YEDV BARA CUSS QSEC TORS GLRK BAES CREC PHOQ CPXA ENVZ ATOS RSTB RCSC RCSD NARX ZRAS DCUS BASS EVGS NARQ ARCB DPIB KDPD PHOR YPDA UHPB
BACSU - YCLK CSSS YKOH YYCG RESE PHOR YVRG YRKQ YVCQ DCTS KINB CITS MALK KIND YCBM YESM YXDK BCES KINE GLNK KINA YBDK KINC LYTS LIAS YWPD COMP
HALSA - Q9HQ15 Q9HQE9 Q9HQG5 Q9HQ16 O51970 Q9HRE4 Q9HR10 Q9HRG1 BAT Q9HNM2 Q9HQB9 Q9HNA6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
385_D	443_V	4.172	1.00
386_I	390_G	4.014	1.00
423_K	427_E	3.808	1.00
310_L	344_A	3.575	1.00
434_T	445_R	3.430	1.00
258_N	278_N	3.269	1.00
383_N	443_V	3.180	1.00
373_T	383_N	2.938	1.00
381_Y	447_T	2.922	1.00
383_N	445_R	2.883	1.00
364_S	387_A	2.868	1.00
396_P	436_H	2.861	1.00
335_K	371_H	2.838	1.00
381_Y	445_R	2.799	1.00
344_A	429_H	2.743	1.00
309_S	343_F	2.705	1.00
375_F	381_Y	2.680	1.00
371_H	385_D	2.668	1.00
255_L	283_E	2.666	1.00
335_K	369_R	2.648	1.00
437_Y	440_K	2.636	1.00
369_R	387_A	2.630	1.00
435_Y	444_F	2.628	1.00
392_K	395_E	2.565	1.00
262_L	279_I	2.561	1.00
213_R	216_K	2.555	1.00
262_L	276_A	2.515	1.00
352_M	426_A	2.489	1.00
422_V	433_A	2.481	1.00
373_T	385_D	2.463	1.00
337_E	373_T	2.443	1.00
309_S	341_Q	2.439	1.00
375_F	383_N	2.432	1.00
426_A	431_G	2.368	1.00
400_F	433_A	2.345	1.00
311_S	314_K	2.345	1.00
391_T	399_L	2.338	1.00
396_P	435_Y	2.286	1.00
225_M	229_L	2.272	1.00
395_E	398_K	2.259	1.00
268_I	271_Y	2.169	1.00
318_N	350_Q	2.144	1.00
337_E	371_H	2.135	1.00
308_D	346_K	2.098	1.00
426_A	446_I	2.073	1.00
333_C	369_R	2.065	1.00
432_S	447_T	2.059	1.00
436_H	442_N	2.056	1.00
398_K	401_R	2.004	1.00
212_P	216_K	1.977	1.00
255_L	282_L	1.975	1.00
323_L	354_S	1.969	1.00
352_M	425_I	1.962	1.00
255_L	286_S	1.945	1.00
238_Q	242_D	1.938	1.00
434_T	447_T	1.923	1.00
344_A	349_L	1.909	1.00
327_S	361_I	1.882	1.00
286_S	290_E	1.874	1.00
307_L	343_F	1.873	1.00
364_S	368_S	1.865	1.00
234_E	238_Q	1.863	1.00
267_S	271_Y	1.852	1.00
352_M	422_V	1.850	1.00
393_I	396_P	1.831	1.00
27_W	31_N	1.812	1.00
425_I	429_H	1.807	1.00
196_A	201_D	1.787	1.00
395_E	404_W	1.782	1.00
358_V	362_R	1.760	1.00
368_S	387_A	1.756	1.00
353_L	382_L	1.743	1.00
226_H	229_L	1.734	1.00
236_L	240_A	1.730	1.00
391_T	442_N	1.726	1.00
398_K	404_W	1.723	1.00
427_E	432_S	1.702	1.00
259_Q	279_I	1.691	1.00
391_T	395_E	1.686	1.00
191_S	217_P	1.664	1.00
386_I	441_H	1.642	1.00
345_D	348_L	1.633	1.00
313_N	317_E	1.626	1.00
267_S	270_E	1.621	1.00
85_D	89_K	1.616	1.00
258_N	279_I	1.611	1.00
371_H	387_A	1.604	1.00
215_L	219_G	1.603	1.00
355_N	422_V	1.581	1.00
262_L	272_Q	1.571	1.00
348_L	351_R	1.561	1.00
395_E	406_G	1.556	1.00
382_L	446_I	1.556	1.00
197_L	226_H	1.550	1.00
257_Q	274_T	1.541	1.00
364_S	370_I	1.523	1.00
379_N	447_T	1.512	1.00
191_S	195_E	1.490	1.00
400_F	435_Y	1.479	1.00
426_A	433_A	1.460	1.00
176_S	180_I	1.459	1.00
436_H	439_N	1.452	1.00
261_T	275_I	1.440	1.00
279_I	283_E	1.428	1.00
219_G	223_N	1.404	1.00
352_M	446_I	1.402	1.00
311_S	341_Q	1.396	1.00
318_N	346_K	1.391	1.00
254_L	282_L	1.385	1.00
346_K	350_Q	1.383	1.00
324_E	328_D	1.375	1.00
322_Y	350_Q	1.375	1.00
313_N	374_S	1.368	1.00
392_K	438_L	1.361	1.00
246_E	351_R	1.360	1.00
396_P	400_F	1.339	1.00
253_A	257_Q	1.338	1.00
401_R	404_W	1.333	1.00
424_A	427_E	1.331	1.00
254_L	278_N	1.327	1.00
436_H	440_K	1.315	1.00
205_P	227_H	1.312	1.00
196_A	204_E	1.298	1.00
210_A	216_K	1.290	1.00
348_L	425_I	1.289	1.00
231_K	235_R	1.288	1.00
348_L	428_L	1.280	1.00
101_L	104_I	1.280	1.00
264_Q	271_Y	1.278	1.00
255_L	279_I	1.275	1.00
400_F	444_F	1.258	1.00
431_G	448_L	1.258	1.00
435_Y	442_N	1.252	1.00
313_N	338_C	1.241	1.00
363_Y	405_R	1.240	1.00
223_N	226_H	1.238	1.00
239_F	243_L	1.235	1.00
201_D	204_E	1.234	1.00
253_A	281_E	1.234	1.00
261_T	271_Y	1.234	1.00
320_L	336_V	1.232	1.00
159_I	163_I	1.222	1.00
276_A	280_E	1.219	1.00
317_E	336_V	1.219	1.00
242_D	402_R	1.210	1.00
194_T	222_L	1.199	1.00
315_E	319_L	1.197	1.00
258_N	262_L	1.192	1.00
360_A	370_I	1.186	1.00
188_K	191_S	1.181	1.00
326_L	329_E	1.176	1.00
400_F	423_K	1.166	1.00
268_I	272_Q	1.160	1.00
399_L	435_Y	1.160	1.00
258_N	282_L	1.158	1.00
338_C	374_S	1.150	1.00
212_P	215_L	1.146	1.00
316_V	374_S	1.143	1.00
365_P	368_S	1.139	1.00
193_V	206_V	1.137	1.00
233_F	236_L	1.135	1.00
34_A	38_K	1.132	1.00
195_E	217_P	1.129	1.00
319_L	354_S	1.128	1.00
28_T	32_G	1.125	1.00
230_V	234_E	1.111	1.00
257_Q	277_G	1.111	1.00
385_D	437_Y	1.108	1.00
248_R	290_E	1.097	1.00
253_A	256_G	1.095	1.00
393_I	436_H	1.093	1.00
181_R	185_R	1.085	1.00
180_I	184_L	1.085	1.00
386_I	442_N	1.082	1.00
155_E	159_I	1.076	1.00
287_R	347_I	1.076	1.00
391_T	396_P	1.074	1.00
349_L	429_H	1.073	1.00
194_T	221_A	1.070	1.00
9_R	213_R	1.064	1.00
405_R	412_S	1.059	1.00
26_V	30_Y	1.054	1.00
307_L	429_H	1.053	1.00
48_R	51_Q	1.051	1.00
208_V	220_Q	1.048	1.00
356_L	444_F	1.045	1.00
7_T	181_R	1.041	1.00
84_G	90_I	1.040	1.00
256_G	260_V	1.039	1.00
205_P	223_N	1.036	1.00
59_G	63_D	1.028	1.00
272_Q	276_A	1.027	1.00
191_S	221_A	1.025	1.00
215_L	218_L	1.025	1.00
232_D	236_L	1.024	1.00
194_T	197_L	1.020	1.00
255_L	259_Q	1.014	1.00
183_G	186_E	1.014	1.00
46_I	50_A	1.006	1.00
319_L	323_L	1.004	1.00
305_V	345_D	1.003	1.00
30_Y	158_K	1.003	1.00
238_Q	402_R	0.996	1.00
353_L	384_I	0.996	1.00
224_K	228_A	0.994	1.00
290_E	294_F	0.992	1.00
273_K	277_G	0.988	1.00
60_V	64_T	0.985	1.00
310_L	315_E	0.984	1.00
265_T	271_Y	0.978	1.00
230_V	233_F	0.976	1.00
246_E	355_N	0.976	1.00
31_N	34_A	0.974	1.00
339_N	375_F	0.974	1.00
353_L	357_I	0.973	1.00
42_D	46_I	0.972	1.00
49_T	53_K	0.970	1.00
291_N	348_L	0.967	1.00
174_V	178_L	0.965	1.00
320_L	324_E	0.962	1.00
293_L	296_A	0.961	1.00
173_S	177_P	0.960	1.00
356_L	433_A	0.960	1.00
61_N	64_T	0.949	1.00
314_K	318_N	0.947	1.00
258_N	275_I	0.946	1.00
319_L	350_Q	0.942	1.00
355_N	358_V	0.939	1.00
198_N	224_K	0.935	1.00
216_K	219_G	0.933	1.00
207_E	223_N	0.931	1.00
402_R	424_A	0.930	1.00
417_L	421_L	0.930	1.00
391_T	435_Y	0.929	1.00
147_A	151_H	0.928	1.00
281_E	284_N	0.926	1.00
323_L	357_I	0.925	1.00
356_L	422_V	0.924	1.00
363_Y	389_P	0.922	1.00
278_N	282_L	0.921	1.00
222_L	225_M	0.919	1.00
332_I	364_S	0.913	1.00
212_P	219_G	0.912	1.00
40_R	44_T	0.912	1.00
317_E	321_D	0.911	1.00
221_A	224_K	0.908	1.00
312_L	382_L	0.908	1.00
277_G	281_E	0.903	1.00
356_L	446_I	0.903	1.00
41_D	44_T	0.897	1.00
180_I	183_G	0.896	1.00
42_D	126_D	0.896	1.00
269_A	272_Q	0.894	1.00
315_E	344_A	0.894	1.00
322_Y	354_S	0.890	1.00
139_L	143_V	0.889	1.00
216_K	220_Q	0.886	1.00
391_T	397_E	0.885	1.00
225_M	228_A	0.884	1.00
426_A	448_L	0.877	1.00
31_N	35_S	0.877	1.00
390_G	442_N	0.877	1.00
399_L	444_F	0.875	1.00
311_S	340_Q	0.871	1.00
205_P	226_H	0.871	1.00
280_E	318_N	0.871	1.00
350_Q	354_S	0.870	1.00
131_N	140_T	0.870	1.00
354_S	358_V	0.868	1.00
53_K	57_I	0.865	1.00
287_R	291_N	0.864	1.00
234_E	237_S	0.864	1.00
273_K	276_A	0.863	1.00
178_L	182_T	0.863	1.00
38_K	42_D	0.863	1.00
347_I	350_Q	0.862	1.00
326_L	358_V	0.859	1.00
194_T	218_L	0.856	1.00
195_E	221_A	0.856	1.00
357_I	372_I	0.855	1.00
282_L	286_S	0.853	1.00
305_V	348_L	0.852	1.00
319_L	357_I	0.852	1.00
40_R	43_T	0.851	1.00
323_L	358_V	0.850	1.00
245_H	249_T	0.848	1.00
240_A	243_L	0.846	1.00
423_K	432_S	0.845	1.00
249_T	253_A	0.844	1.00
159_I	162_I	0.837	1.00
158_K	162_I	0.837	1.00
422_V	426_A	0.836	1.00
283_E	286_S	0.830	1.00
140_T	144_A	0.829	1.00
271_Y	274_T	0.828	1.00
133_D	136_S	0.825	1.00
44_T	47_N	0.824	1.00
135_V	138_S	0.824	1.00
156_Q	160_N	0.821	1.00
197_L	225_M	0.821	1.00
226_H	230_V	0.817	1.00
246_E	250_P	0.816	1.00
102_N	105_P	0.813	1.00
245_H	355_N	0.812	1.00
193_V	204_E	0.810	1.00
235_R	238_Q	0.810	1.00
376_L	380_S	0.808	1.00
36_E	40_R	0.807	1.00
312_L	380_S	0.807	1.00
424_A	428_L	0.806	1.00
307_L	430_G	0.806	1.00
393_I	397_E	0.805	1.00
218_L	222_L	0.803	1.00
194_T	198_N	0.802	1.00
313_N	340_Q	0.801	1.00
192_G	196_A	0.799	1.00
348_L	352_M	0.799	1.00
217_P	220_Q	0.798	1.00
49_T	52_I	0.798	1.00
252_N	256_G	0.797	1.00
332_I	336_V	0.796	1.00
372_I	384_I	0.796	1.00
206_V	219_G	0.795	1.00
41_D	45_L	0.795	1.00
129_R	140_T	0.795	1.00
316_V	353_L	0.795	1.00
276_A	279_I	0.795	1.00
191_S	194_T	0.791	1.00
206_V	223_N	0.788	1.00
96_V	99_G	0.788	1.00
177_P	181_R	0.787	1.00
421_L	425_I	0.781	1.00
45_L	49_T	0.780	1.00
260_V	264_Q	0.778	1.00
321_D	324_E	0.776	1.00
377_D	381_Y	0.774	1.00
431_G	446_I	0.774	1.00
231_K	234_E	0.773	1.00
295_L	420_S	0.772	1.00
17_L	21_A	0.771	1.00
188_K	192_G	0.771	1.00
352_M	429_H	0.769	1.00
294_F	351_R	0.769	1.00
306_K	345_D	0.766	1.00
44_T	48_R	0.763	1.00
59_G	62_P	0.763	1.00
79_I	82_I	0.761	1.00
126_D	129_R	0.757	1.00
232_D	235_R	0.755	1.00
208_V	219_G	0.755	1.00
248_R	286_S	0.752	1.00
82_I	142_T	0.751	1.00
327_S	334_F	0.751	1.00
251_I	289_T	0.751	1.00
307_L	344_A	0.751	1.00
198_N	228_A	0.750	1.00
126_D	131_N	0.749	1.00
182_T	185_R	0.749	1.00
392_K	406_G	0.749	1.00
98_D	101_L	0.748	1.00
233_F	237_S	0.747	1.00
310_L	346_K	0.747	1.00
190_L	194_T	0.746	1.00
23_A	27_W	0.743	1.00
327_S	370_I	0.743	1.00
154_L	158_K	0.742	1.00
316_V	372_I	0.741	1.00
247_L	285_I	0.741	1.00
277_G	280_E	0.739	1.00
186_E	190_L	0.739	1.00
124_E	127_A	0.738	1.00
351_R	425_I	0.738	1.00
57_I	61_N	0.733	1.00
210_A	213_R	0.732	1.00
317_E	320_L	0.730	1.00
374_S	380_S	0.729	1.00
66_P	70_N	0.728	1.00
356_L	426_A	0.728	1.00
333_C	336_V	0.728	1.00
43_T	46_I	0.725	1.00
125_I	129_R	0.725	1.00
195_E	199_Y	0.721	1.00
185_R	189_K	0.721	1.00
30_Y	34_A	0.720	1.00
162_I	166_I	0.717	1.00
243_L	292_I	0.717	1.00
257_Q	281_E	0.717	1.00
331_E	367_K	0.717	1.00
386_I	389_P	0.717	1.00
193_V	196_A	0.716	1.00
60_V	63_D	0.709	1.00
395_E	408_N	0.708	1.00
433_A	444_F	0.707	1.00
52_I	55_L	0.706	1.00
328_D	331_E	0.706	1.00
85_D	91_V	0.705	1.00
39_W	42_D	0.699	1.00
405_R	414_G	0.699	1.00
305_V	428_L	0.698	1.00
389_P	412_S	0.696	1.00
319_L	322_Y	0.696	1.00
129_R	142_T	0.695	1.00
362_R	412_S	0.695	1.00
218_L	221_A	0.695	1.00
400_F	403_F	0.693	1.00
189_K	193_V	0.692	1.00
327_S	330_K	0.690	1.00
320_L	334_F	0.690	1.00
110_I	113_A	0.690	1.00
213_R	217_P	0.687	1.00
325_Y	329_E	0.687	1.00
360_A	384_I	0.687	1.00
54_Q	58_D	0.686	1.00
195_E	198_N	0.685	1.00
326_L	330_K	0.685	1.00
50_A	54_Q	0.684	1.00
69_F	72_M	0.683	1.00
391_T	436_H	0.682	1.00
317_E	338_C	0.682	1.00
217_P	221_A	0.680	1.00
189_K	192_G	0.680	1.00
401_R	423_K	0.679	1.00
312_L	342_I	0.679	1.00
385_D	439_N	0.679	1.00
45_L	48_R	0.678	1.00
325_Y	328_D	0.678	1.00
393_I	437_Y	0.677	1.00
291_N	351_R	0.674	1.00
237_S	299_D	0.672	1.00
374_S	382_L	0.669	1.00
150_R	154_L	0.668	1.00
321_D	325_Y	0.668	1.00
257_Q	278_N	0.667	1.00
310_L	343_F	0.666	1.00
38_K	41_D	0.666	1.00
55_L	58_D	0.665	1.00
47_N	50_A	0.665	1.00
348_L	429_H	0.665	1.00
7_T	188_K	0.664	1.00
365_P	389_P	0.664	1.00
396_P	444_F	0.664	1.00
127_A	130_I	0.663	1.00
364_S	367_K	0.662	1.00
219_G	222_L	0.662	1.00
37_L	40_R	0.660	1.00
331_E	366_E	0.660	1.00
240_A	244_A	0.659	1.00
80_L	93_R	0.658	1.00
27_W	30_Y	0.657	1.00
262_L	275_I	0.656	1.00
318_N	322_Y	0.654	1.00
35_S	39_W	0.649	1.00
274_T	278_N	0.649	1.00
237_S	242_D	0.648	1.00
270_E	274_T	0.648	1.00
257_Q	261_T	0.648	1.00
54_Q	57_I	0.648	1.00
155_E	158_K	0.645	1.00
127_A	144_A	0.645	1.00
68_Y	73_M	0.645	1.00
80_L	144_A	0.644	1.00
422_V	425_I	0.643	1.00
42_D	45_L	0.642	1.00
281_E	322_Y	0.642	1.00
284_N	350_Q	0.642	1.00
190_L	219_G	0.641	1.00
151_H	155_E	0.637	1.00
377_D	447_T	0.637	1.00
125_I	128_L	0.636	1.00
187_I	218_L	0.634	1.00
294_F	297_R	0.634	1.00
399_L	404_W	0.632	1.00
370_I	384_I	0.632	1.00
279_I	282_L	0.632	1.00
24_G	28_T	0.631	1.00
265_T	268_I	0.631	1.00
62_P	65_L	0.630	1.00
100_M	103_N	0.628	1.00
252_N	255_L	0.628	1.00
362_R	414_G	0.627	1.00
241_D	244_A	0.624	1.00
43_T	47_N	0.624	1.00
32_G	35_S	0.623	1.00
35_S	38_K	0.623	1.00
314_K	346_K	0.622	1.00
399_L	420_S	0.621	1.00
210_A	219_G	0.621	1.00
420_S	424_A	0.620	1.00
337_E	375_F	0.619	1.00
50_A	53_K	0.617	1.00
84_G	142_T	0.617	1.00
327_S	332_I	0.616	1.00
156_Q	159_I	0.616	1.00
294_F	348_L	0.616	1.00
36_E	39_W	0.615	1.00
381_Y	434_T	0.615	1.00
434_T	446_I	0.614	1.00
247_L	250_P	0.614	1.00
390_G	441_H	0.612	1.00
32_G	36_E	0.612	1.00
293_L	297_R	0.611	1.00
357_I	370_I	0.610	1.00
239_F	246_E	0.609	1.00
274_T	277_G	0.608	1.00
166_I	170_V	0.608	1.00
58_D	61_N	0.606	1.00
186_E	213_R	0.606	1.00
90_I	93_R	0.606	1.00
182_T	186_E	0.604	1.00
323_L	361_I	0.604	1.00
239_F	242_D	0.604	1.00
15_I	18_L	0.602	1.00
320_L	372_I	0.601	1.00
13_L	17_L	0.600	1.00
396_P	442_N	0.600	1.00
253_A	277_G	0.600	1.00
254_L	258_N	0.599	1.00
118_S	121_N	0.599	1.00
332_I	361_I	0.598	1.00
110_I	114_G	0.598	1.00
299_D	402_R	0.597	1.00
70_N	74_D	0.597	1.00
365_P	387_A	0.597	1.00
55_L	59_G	0.592	1.00
85_D	88_N	0.592	1.00
204_E	208_V	0.590	1.00
9_R	182_T	0.589	1.00
391_T	444_F	0.588	1.00
242_D	246_E	0.588	1.00
160_N	163_I	0.585	1.00
49_T	143_V	0.585	1.00
194_T	225_M	0.582	1.00
185_R	188_K	0.581	1.00
68_Y	71_R	0.580	1.00
431_G	449_P	0.580	1.00
14_F	176_S	0.579	1.00
82_I	90_I	0.578	1.00
28_T	31_N	0.576	1.00
397_E	401_R	0.576	1.00
246_E	421_L	0.573	1.00
8_V	12_L	0.572	1.00
163_I	167_V	0.572	1.00
172_C	176_S	0.571	1.00
125_I	144_A	0.569	1.00
70_N	73_M	0.569	1.00
121_N	124_E	0.568	1.00
245_H	250_P	0.567	1.00
409_S	413_V	0.567	1.00
285_I	289_T	0.566	1.00
224_K	227_H	0.565	1.00
136_S	139_L	0.565	1.00
141_V	146_L	0.565	1.00
339_N	373_T	0.565	1.00
315_E	349_L	0.564	1.00
218_L	223_N	0.563	1.00
275_I	279_I	0.563	1.00
220_Q	224_K	0.563	1.00
187_I	215_L	0.560	1.00
405_R	413_V	0.559	1.00
39_W	43_T	0.558	1.00
48_R	52_I	0.557	1.00
16_L	23_A	0.557	1.00
238_Q	424_A	0.556	1.00
264_Q	274_T	0.556	1.00
295_L	424_A	0.556	1.00
339_N	374_S	0.555	1.00
16_L	19_S	0.555	1.00
260_V	274_T	0.554	1.00
209_S	212_P	0.553	1.00
192_G	195_E	0.551	1.00
61_N	65_L	0.550	1.00
50_A	130_I	0.550	1.00
357_I	361_I	0.550	1.00
68_Y	72_M	0.549	1.00
227_H	231_K	0.548	1.00
207_E	210_A	0.547	1.00
246_E	249_T	0.547	1.00
139_L	145_K	0.546	1.00
349_L	448_L	0.545	1.00
56_L	60_V	0.545	1.00
208_V	216_K	0.544	1.00
239_F	244_A	0.544	1.00
283_E	287_R	0.544	1.00
236_L	244_A	0.544	1.00
261_T	274_T	0.543	1.00
190_L	222_L	0.542	1.00
389_P	442_N	0.540	1.00
360_A	364_S	0.540	1.00
197_L	202_S	0.539	1.00
342_I	380_S	0.539	1.00
19_S	23_A	0.539	1.00
67_V	70_N	0.538	1.00
187_I	191_S	0.538	1.00
286_S	289_T	0.536	1.00
202_S	226_H	0.535	1.00
121_N	125_I	0.535	1.00
146_L	149_A	0.535	1.00
120_I	123_T	0.534	1.00
98_D	103_N	0.534	1.00
257_Q	282_L	0.534	1.00
67_V	71_R	0.532	1.00
189_K	207_E	0.531	1.00
133_D	137_P	0.531	1.00
314_K	317_E	0.531	1.00
33_L	36_E	0.530	1.00
193_V	223_N	0.530	1.00
259_Q	262_L	0.529	1.00
262_L	265_T	0.529	1.00
292_I	296_A	0.528	1.00
184_L	188_K	0.528	1.00
392_K	396_P	0.525	1.00
49_T	130_I	0.525	1.00
256_G	282_L	0.524	1.00
318_N	321_D	0.524	1.00
322_Y	326_L	0.523	1.00
252_N	257_Q	0.522	1.00
222_L	226_H	0.522	1.00
426_A	432_S	0.522	1.00
305_V	429_H	0.521	1.00
181_R	188_K	0.520	1.00
51_Q	55_L	0.520	1.00
196_A	199_Y	0.520	1.00
228_A	231_K	0.520	1.00
246_E	288_L	0.518	1.00
260_V	265_T	0.518	1.00
135_V	139_L	0.518	1.00
316_V	319_L	0.518	1.00
330_K	361_I	0.518	1.00
98_D	102_N	0.516	1.00
310_L	349_L	0.515	1.00
150_R	153_M	0.514	1.00
371_H	374_S	0.513	1.00
18_L	21_A	0.513	1.00
14_F	17_L	0.512	1.00
51_Q	54_Q	0.510	1.00
441_H	444_F	0.508	1.00
152_N	156_Q	0.508	1.00
128_L	132_I	0.507	1.00
330_K	366_E	0.507	1.00
251_I	257_Q	0.507	1.00
291_N	347_I	0.506	1.00
237_S	241_D	0.505	1.00
285_I	293_L	0.504	1.00
208_V	213_R	0.504	1.00
71_R	75_V	0.502	1.00
99_G	103_N	0.502	1.00
18_L	172_C	0.502	1.00
361_I	364_S	0.501	1.00
26_V	165_C	0.501	1.00
201_D	205_P	0.500	1.00
219_G	226_H	0.500	1.00
47_N	51_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5929	100	0.355	Contact Map
4bixA	2	0.4934	100	0.406	Contact Map
4ctiA	2	0.5022	100	0.431	Contact Map
4q20A	2	0.5	100	0.468	Contact Map
3jz3A	2	0.3496	100	0.484	Contact Map
3a0rA	2	0.7212	100	0.486	Contact Map
4gczA	2	0.7721	100	0.492	Contact Map
4mpcA	2	0.646	100	0.492	Contact Map
4e01A	3	0.6261	100	0.501	Contact Map
2c2aA	2	0.5066	100	0.504	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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