YEDQ - ECOLI - GREMLIN Contacts

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YEDQ - Probable diguanylate cyclase YedQ

UniProt:	P76330	Sequences: MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRDAVTEFEQHRDEHAWKIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14040
Length:	564 (438)
Sequences:	2219 (1949)
Seq/√Len:	93.1

ECOLI - YEDQ YEGE DOSP YEAJ YDAM DOSC GMR YLIF YLIE
BACSU - YTRP YKOW

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
468_R	471_D	6.352	1.00
433_I	523_L	6.328	1.00
387_M	391_Q	5.052	1.00
412_L	482_C	4.495	1.00
439_H	555_R	4.234	1.00
431_S	527_S	4.082	1.00
396_W	400_H	3.813	1.00
433_I	497_A	3.772	1.00
529_E	532_G	3.731	1.00
498_E	501_R	3.534	1.00
535_D	538_Q	3.284	1.00
550_A	559_F	3.221	1.00
454_R	457_S	2.952	1.00
505_N	556_N	2.883	1.00
425_T	468_R	2.774	1.00
467_L	473_A	2.763	1.00
501_R	558_V	2.735	1.00
504_L	521_A	2.679	1.00
434_Q	547_L	2.672	1.00
245_D	249_Y	2.667	1.00
520_S	556_N	2.622	1.00
407_Y	411_A	2.611	1.00
419_L	422_L	2.611	1.00
267_L	271_I	2.584	1.00
459_A	504_L	2.507	1.00
544_D	548_Y	2.505	1.00
416_A	536_F	2.490	1.00
412_L	484_I	2.468	1.00
493_A	497_A	2.436	1.00
498_E	502_L	2.417	1.00
485_L	496_V	2.409	1.00
178_S	182_F	2.387	1.00
438_D	522_S	2.191	1.00
449_H	544_D	2.183	1.00
431_S	493_A	2.153	1.00
458_H	461_G	2.142	1.00
450_Q	541_S	2.123	1.00
462_L	508_E	2.118	1.00
243_P	252_G	2.111	1.00
415_K	472_V	2.063	1.00
532_G	542_L	2.043	1.00
388_Y	391_Q	2.036	1.00
455_V	519_I	2.026	1.00
441_K	445_D	2.018	1.00
406_L	460_A	2.001	1.00
445_D	548_Y	2.001	1.00
411_A	415_K	1.995	1.00
437_L	521_A	1.994	1.00
407_Y	472_V	1.989	1.00
525_V	558_V	1.961	1.00
391_Q	395_Q	1.953	1.00
449_H	548_Y	1.948	1.00
277_G	382_R	1.928	1.00
443_I	455_V	1.900	1.00
392_S	395_Q	1.896	1.00
488_A	492_E	1.891	1.00
305_R	353_G	1.879	1.00
267_L	272_D	1.865	1.00
489_S	492_E	1.860	1.00
497_A	525_V	1.830	1.00
463_I	473_A	1.822	1.00
501_R	505_N	1.818	1.00
437_L	459_A	1.802	1.00
479_E	520_S	1.793	1.00
283_D	287_R	1.792	1.00
411_A	472_V	1.770	1.00
441_K	544_D	1.769	1.00
478_G	544_D	1.769	1.00
479_E	547_L	1.744	1.00
437_L	456_L	1.707	1.00
140_L	144_N	1.702	1.00
463_I	500_I	1.665	1.00
553_A	559_F	1.662	1.00
529_E	542_L	1.644	1.00
434_Q	482_C	1.637	1.00
436_D	548_Y	1.636	1.00
441_K	449_H	1.633	1.00
478_G	548_Y	1.622	1.00
280_Q	288_F	1.610	1.00
412_L	474_G	1.610	1.00
455_V	509_M	1.605	1.00
435_V	483_V	1.603	1.00
369_F	373_L	1.580	1.00
449_H	480_E	1.558	1.00
437_L	520_S	1.554	1.00
243_P	250_W	1.536	1.00
501_R	556_N	1.533	1.00
541_S	545_R	1.517	1.00
384_V	388_Y	1.504	1.00
445_D	544_D	1.500	1.00
301_I	305_R	1.496	1.00
455_V	479_E	1.485	1.00
449_H	478_G	1.482	1.00
439_H	479_E	1.479	1.00
443_I	517_I	1.463	1.00
531_T	542_L	1.461	1.00
441_K	548_Y	1.451	1.00
434_Q	479_E	1.448	1.00
477_G	548_Y	1.445	1.00
549_L	552_Q	1.443	1.00
419_L	486_P	1.433	0.99
477_G	544_D	1.432	0.99
384_V	391_Q	1.425	0.99
435_V	523_L	1.424	0.99
280_Q	379_V	1.423	0.99
399_W	410_G	1.416	0.99
436_D	445_D	1.416	0.99
458_H	462_L	1.415	0.99
411_A	414_E	1.407	0.99
292_S	383_M	1.406	0.99
266_F	271_I	1.387	0.99
433_I	483_V	1.385	0.99
438_D	554_G	1.384	0.99
443_I	511_I	1.378	0.99
301_I	353_G	1.362	0.99
204_T	230_H	1.355	0.99
479_E	555_R	1.355	0.99
440_F	456_L	1.352	0.99
425_T	471_D	1.350	0.99
461_G	464_S	1.332	0.99
445_D	449_H	1.327	0.99
514_S	517_I	1.326	0.99
547_L	555_R	1.323	0.99
436_D	441_K	1.323	0.99
406_L	473_A	1.310	0.99
480_E	544_D	1.310	0.99
435_V	521_A	1.309	0.99
419_L	430_F	1.307	0.99
483_V	500_I	1.307	0.99
436_D	544_D	1.303	0.99
390_L	397_Q	1.297	0.99
447_F	515_T	1.277	0.99
501_R	520_S	1.270	0.99
497_A	558_V	1.266	0.99
550_A	554_G	1.256	0.99
263_M	267_L	1.253	0.99
339_G	346_T	1.247	0.99
439_H	547_L	1.246	0.99
359_S	385_S	1.242	0.99
393_S	397_Q	1.240	0.98
414_E	472_V	1.240	0.98
361_A	382_R	1.227	0.98
431_S	488_A	1.226	0.98
383_M	387_M	1.217	0.98
292_S	295_D	1.215	0.98
245_D	251_Y	1.201	0.98
383_M	391_Q	1.196	0.98
528_S	532_G	1.196	0.98
444_N	452_G	1.177	0.98
437_L	479_E	1.176	0.98
531_T	560_A	1.175	0.98
480_E	548_Y	1.170	0.98
445_D	478_G	1.168	0.98
413_F	476_V	1.163	0.98
476_V	479_E	1.160	0.98
529_E	539_L	1.157	0.98
550_A	557_R	1.150	0.98
442_A	446_R	1.147	0.97
437_L	478_G	1.145	0.97
391_Q	394_L	1.133	0.97
522_S	544_D	1.128	0.97
158_G	162_R	1.122	0.97
202_Y	208_F	1.120	0.97
455_V	474_G	1.119	0.97
175_M	255_G	1.117	0.97
278_E	292_S	1.112	0.97
548_Y	555_R	1.106	0.97
264_Q	267_L	1.105	0.97
423_C	430_F	1.101	0.97
327_R	331_W	1.099	0.97
415_K	418_P	1.097	0.97
278_E	381_R	1.095	0.97
430_F	539_L	1.095	0.97
378_Y	381_R	1.093	0.97
488_A	493_A	1.088	0.97
144_N	147_L	1.078	0.96
463_I	467_L	1.073	0.96
428_H	487_G	1.069	0.96
527_S	560_A	1.068	0.96
133_L	137_G	1.068	0.96
292_S	385_S	1.064	0.96
526_S	539_L	1.059	0.96
522_S	548_Y	1.055	0.96
462_L	509_M	1.054	0.96
316_H	319_R	1.054	0.96
419_L	472_V	1.052	0.96
366_W	376_S	1.044	0.96
132_A	143_E	1.043	0.96
412_L	432_V	1.038	0.95
447_F	455_V	1.035	0.95
494_A	558_V	1.032	0.95
266_F	272_D	1.030	0.95
414_E	418_P	1.025	0.95
128_G	131_D	1.024	0.95
445_D	480_E	1.021	0.95
400_H	479_E	1.020	0.95
208_F	253_V	1.020	0.95
455_V	511_I	1.019	0.95
352_R	356_G	1.018	0.95
201_G	204_T	1.006	0.95
258_I	263_M	1.003	0.95
511_I	517_I	1.001	0.94
549_L	553_A	1.000	0.94
462_L	511_I	0.996	0.94
224_F	239_T	0.996	0.94
497_A	523_L	0.992	0.94
157_V	161_L	0.989	0.94
549_L	559_F	0.986	0.94
352_R	355_F	0.986	0.94
434_Q	540_Q	0.979	0.94
434_Q	476_V	0.975	0.94
466_S	499_R	0.972	0.94
133_L	144_N	0.971	0.94
416_A	484_I	0.968	0.93
508_E	511_I	0.968	0.93
479_E	558_V	0.964	0.93
397_Q	443_I	0.964	0.93
399_W	411_A	0.963	0.93
520_S	554_G	0.960	0.93
443_I	509_M	0.959	0.93
178_S	184_V	0.956	0.93
137_G	140_L	0.955	0.93
362_L	379_V	0.955	0.93
281_L	376_S	0.953	0.93
365_L	378_Y	0.943	0.93
526_S	542_L	0.943	0.93
386_N	389_V	0.943	0.93
446_R	541_S	0.941	0.92
526_S	532_G	0.937	0.92
467_L	496_V	0.936	0.92
390_L	394_L	0.932	0.92
176_Y	181_G	0.926	0.92
439_H	442_A	0.926	0.92
281_L	292_S	0.925	0.92
451_A	511_I	0.920	0.92
468_R	499_R	0.918	0.91
337_F	340_V	0.915	0.91
438_D	544_D	0.914	0.91
351_V	354_D	0.913	0.91
475_R	480_E	0.906	0.91
364_L	377_W	0.905	0.91
265_Q	268_R	0.904	0.91
208_F	252_G	0.903	0.91
268_R	273_K	0.903	0.91
129_V	136_E	0.896	0.90
542_L	561_S	0.895	0.90
361_A	387_M	0.893	0.90
410_G	479_E	0.890	0.90
395_Q	399_W	0.882	0.90
476_V	540_Q	0.880	0.90
136_E	139_L	0.880	0.90
181_G	186_T	0.879	0.90
160_L	163_L	0.878	0.90
526_S	529_E	0.878	0.90
282_Y	288_F	0.874	0.89
440_F	459_A	0.872	0.89
434_Q	455_V	0.872	0.89
476_V	482_C	0.871	0.89
454_R	513_K	0.871	0.89
129_V	133_L	0.870	0.89
239_T	257_S	0.869	0.89
438_D	548_Y	0.869	0.89
312_Q	319_R	0.868	0.89
372_M	383_M	0.864	0.89
202_Y	207_W	0.864	0.89
496_V	499_R	0.862	0.89
442_A	479_E	0.860	0.89
445_D	477_G	0.859	0.89
114_W	118_L	0.858	0.88
451_A	517_I	0.858	0.88
199_Y	202_Y	0.857	0.88
400_H	411_A	0.855	0.88
355_F	359_S	0.850	0.88
309_L	313_A	0.849	0.88
161_L	164_A	0.849	0.88
400_H	547_L	0.848	0.88
466_S	503_K	0.848	0.88
223_W	226_S	0.843	0.88
223_W	227_Q	0.840	0.87
160_L	164_A	0.836	0.87
509_M	519_I	0.835	0.87
430_F	528_S	0.833	0.87
402_T	410_G	0.832	0.87
498_E	558_V	0.828	0.87
522_S	554_G	0.827	0.87
436_D	551_K	0.826	0.87
302_F	305_R	0.825	0.86
441_K	480_E	0.823	0.86
407_Y	415_K	0.822	0.86
278_E	298_T	0.821	0.86
425_T	470_Q	0.819	0.86
300_N	355_F	0.812	0.86
142_R	145_E	0.810	0.85
352_R	358_I	0.810	0.85
474_G	482_C	0.810	0.85
154_A	158_G	0.808	0.85
467_L	483_V	0.807	0.85
459_A	463_I	0.807	0.85
479_E	556_N	0.807	0.85
477_G	555_R	0.807	0.85
459_A	519_I	0.806	0.85
494_A	498_E	0.806	0.85
329_V	333_R	0.797	0.85
528_S	539_L	0.797	0.85
528_S	531_T	0.797	0.85
389_V	393_S	0.797	0.85
455_V	476_V	0.795	0.84
319_R	323_R	0.793	0.84
473_A	483_V	0.791	0.84
468_R	488_A	0.787	0.84
432_V	539_L	0.787	0.84
412_L	540_Q	0.786	0.84
438_D	441_K	0.785	0.84
436_D	449_H	0.784	0.84
156_E	161_L	0.784	0.84
449_H	522_S	0.783	0.83
409_R	453_D	0.780	0.83
236_P	239_T	0.780	0.83
510_L	516_T	0.780	0.83
291_S	296_H	0.778	0.83
178_S	181_G	0.777	0.83
335_D	339_G	0.776	0.83
417_R	536_F	0.776	0.83
473_A	500_I	0.776	0.83
485_L	493_A	0.775	0.83
175_M	183_Y	0.772	0.83
432_V	540_Q	0.772	0.83
393_S	396_W	0.772	0.83
137_G	144_N	0.771	0.83
462_L	501_R	0.771	0.83
400_H	407_Y	0.769	0.82
398_A	477_G	0.767	0.82
115_K	119_N	0.764	0.82
282_Y	377_W	0.764	0.82
410_G	555_R	0.763	0.82
466_S	500_I	0.761	0.82
398_A	547_L	0.759	0.82
311_A	315_E	0.755	0.81
436_D	477_G	0.755	0.81
433_I	525_V	0.754	0.81
111_E	114_W	0.753	0.81
131_D	134_V	0.751	0.81
479_E	548_Y	0.750	0.81
387_M	390_L	0.748	0.81
135_S	138_N	0.748	0.81
224_F	238_V	0.748	0.81
544_D	555_R	0.747	0.80
504_L	519_I	0.743	0.80
350_G	354_D	0.742	0.80
528_S	547_L	0.742	0.80
318_T	359_S	0.742	0.80
437_L	547_L	0.741	0.80
398_A	544_D	0.737	0.80
478_G	522_S	0.735	0.79
532_G	539_L	0.734	0.79
415_K	419_L	0.732	0.79
201_G	207_W	0.731	0.79
274_N	277_G	0.726	0.79
479_E	511_I	0.725	0.78
277_G	281_L	0.725	0.78
236_P	242_V	0.724	0.78
268_R	272_D	0.723	0.78
125_P	130_S	0.722	0.78
206_P	209_I	0.719	0.78
397_Q	410_G	0.717	0.78
451_A	454_R	0.717	0.78
462_L	479_E	0.717	0.78
211_H	241_S	0.716	0.78
229_E	233_N	0.716	0.78
200_Y	204_T	0.715	0.78
480_E	522_S	0.715	0.78
438_D	445_D	0.715	0.78
133_L	136_E	0.714	0.77
132_A	136_E	0.713	0.77
501_R	523_L	0.713	0.77
254_L	259_P	0.712	0.77
278_E	383_M	0.711	0.77
140_L	148_D	0.708	0.77
241_S	253_V	0.708	0.77
277_G	361_A	0.708	0.77
468_R	496_V	0.706	0.77
441_K	478_G	0.703	0.76
444_N	478_G	0.703	0.76
415_K	484_I	0.703	0.76
288_F	328_Y	0.702	0.76
201_G	205_Q	0.702	0.76
409_R	449_H	0.701	0.76
396_W	479_E	0.701	0.76
366_W	374_L	0.700	0.76
440_F	554_G	0.700	0.76
447_F	479_E	0.699	0.76
531_T	539_L	0.696	0.76
438_D	449_H	0.692	0.75
113_A	116_I	0.689	0.75
227_Q	239_T	0.689	0.75
128_G	140_L	0.688	0.75
493_A	527_S	0.686	0.75
291_S	299_G	0.684	0.74
212_S	250_W	0.682	0.74
420_A	430_F	0.681	0.74
438_D	555_R	0.680	0.74
522_S	551_K	0.678	0.74
435_V	463_I	0.678	0.74
394_L	399_W	0.678	0.74
403_L	452_G	0.676	0.73
181_G	208_F	0.675	0.73
479_E	517_I	0.674	0.73
438_D	478_G	0.674	0.73
407_Y	474_G	0.672	0.73
354_D	358_I	0.672	0.73
222_R	226_S	0.670	0.73
399_W	547_L	0.667	0.73
422_L	425_T	0.666	0.72
432_V	526_S	0.666	0.72
316_H	320_G	0.665	0.72
128_G	132_A	0.665	0.72
384_V	387_M	0.665	0.72
361_A	365_L	0.664	0.72
492_E	495_E	0.664	0.72
477_G	480_E	0.664	0.72
377_W	381_R	0.664	0.72
493_A	525_V	0.662	0.72
113_A	119_N	0.661	0.72
171_V	187_Q	0.660	0.72
282_Y	311_A	0.659	0.72
176_Y	244_V	0.658	0.71
124_L	132_A	0.657	0.71
441_K	453_D	0.655	0.71
201_G	226_S	0.655	0.71
419_L	425_T	0.655	0.71
168_S	187_Q	0.654	0.71
436_D	478_G	0.652	0.71
445_D	551_K	0.651	0.71
362_L	365_L	0.649	0.70
237_Q	257_S	0.648	0.70
544_D	551_K	0.648	0.70
355_F	358_I	0.648	0.70
478_G	547_L	0.646	0.70
327_R	340_V	0.644	0.70
463_I	483_V	0.643	0.70
436_D	475_R	0.643	0.70
204_T	236_P	0.642	0.70
174_A	256_M	0.642	0.70
454_R	458_H	0.639	0.69
452_G	478_G	0.638	0.69
311_A	316_H	0.637	0.69
240_V	243_P	0.637	0.69
355_F	383_M	0.637	0.69
476_V	547_L	0.637	0.69
490_L	530_E	0.636	0.69
453_D	544_D	0.634	0.69
125_P	136_E	0.633	0.69
475_R	478_G	0.630	0.68
136_E	140_L	0.630	0.68
436_D	453_D	0.630	0.68
210_G	214_R	0.630	0.68
489_S	557_R	0.629	0.68
240_V	252_G	0.629	0.68
440_F	550_A	0.628	0.68
376_S	380_I	0.627	0.68
141_S	148_D	0.626	0.68
398_A	440_F	0.625	0.68
235_E	259_P	0.622	0.67
175_M	181_G	0.622	0.67
339_G	354_D	0.619	0.67
511_I	547_L	0.619	0.67
226_S	229_E	0.618	0.67
295_D	306_E	0.618	0.67
112_H	115_K	0.617	0.67
327_R	339_G	0.615	0.66
453_D	475_R	0.615	0.66
122_R	130_S	0.614	0.66
468_R	548_Y	0.614	0.66
173_Q	257_S	0.612	0.66
207_W	230_H	0.610	0.66
288_F	364_L	0.610	0.66
221_V	234_T	0.610	0.66
442_A	520_S	0.610	0.66
138_N	142_R	0.609	0.66
305_R	309_L	0.609	0.66
203_V	208_F	0.609	0.66
143_E	162_R	0.607	0.65
497_A	554_G	0.607	0.65
430_F	484_I	0.607	0.65
238_V	252_G	0.607	0.65
267_L	273_K	0.606	0.65
132_A	146_S	0.604	0.65
554_G	557_R	0.604	0.65
205_Q	209_I	0.604	0.65
420_A	532_G	0.603	0.65
413_F	474_G	0.603	0.65
278_E	385_S	0.602	0.65
350_G	359_S	0.601	0.65
393_S	456_L	0.601	0.65
400_H	410_G	0.600	0.64
383_M	386_N	0.599	0.64
281_L	378_Y	0.599	0.64
443_I	519_I	0.598	0.64
311_A	317_D	0.598	0.64
299_G	306_E	0.597	0.64
351_V	355_F	0.597	0.64
324_M	328_Y	0.597	0.64
173_Q	187_Q	0.596	0.64
275_L	385_S	0.596	0.64
405_R	460_A	0.594	0.64
415_K	474_G	0.590	0.63
459_A	509_M	0.590	0.63
421_K	469_A	0.590	0.63
204_T	226_S	0.588	0.63
291_S	301_I	0.587	0.63
221_V	225_T	0.587	0.63
434_Q	520_S	0.586	0.63
432_V	450_Q	0.586	0.63
229_E	234_T	0.586	0.63
279_Y	292_S	0.585	0.62
159_Y	163_L	0.584	0.62
132_A	141_S	0.583	0.62
545_R	556_N	0.583	0.62
303_D	307_L	0.583	0.62
438_D	520_S	0.582	0.62
153_A	161_L	0.581	0.62
449_H	477_G	0.581	0.62
167_S	171_V	0.581	0.62
441_K	522_S	0.580	0.62
398_A	441_K	0.579	0.62
161_L	167_S	0.578	0.62
141_S	144_N	0.577	0.61
247_N	251_Y	0.577	0.61
290_T	303_D	0.577	0.61
294_P	297_P	0.577	0.61
128_G	135_S	0.576	0.61
460_A	473_A	0.574	0.61
327_R	337_F	0.573	0.61
353_G	358_I	0.571	0.61
453_D	478_G	0.571	0.61
136_E	143_E	0.571	0.61
394_L	486_P	0.570	0.61
430_F	434_Q	0.567	0.60
243_P	256_M	0.566	0.60
467_L	471_D	0.566	0.60
142_R	169_S	0.566	0.60
499_R	504_L	0.565	0.60
257_S	262_T	0.564	0.60
399_W	414_E	0.564	0.60
383_M	388_Y	0.563	0.60
174_A	187_Q	0.562	0.59
398_A	434_Q	0.562	0.59
323_R	343_R	0.561	0.59
132_A	135_S	0.561	0.59
436_D	480_E	0.560	0.59
314_M	318_T	0.560	0.59
113_A	117_E	0.560	0.59
495_E	499_R	0.559	0.59
209_I	302_F	0.558	0.59
452_G	551_K	0.557	0.59
404_T	456_L	0.557	0.59
158_G	161_L	0.557	0.59
224_F	264_Q	0.556	0.59
529_E	535_D	0.554	0.58
278_E	295_D	0.553	0.58
176_Y	255_G	0.552	0.58
438_D	480_E	0.552	0.58
504_L	509_M	0.552	0.58
331_W	379_V	0.552	0.58
264_Q	268_R	0.552	0.58
132_A	148_D	0.551	0.58
547_L	558_V	0.550	0.58
116_I	119_N	0.550	0.58
400_H	560_A	0.548	0.58
413_F	537_E	0.547	0.57
390_L	499_R	0.547	0.57
479_E	501_R	0.547	0.57
159_Y	162_R	0.547	0.57
323_R	327_R	0.545	0.57
133_L	162_R	0.545	0.57
447_F	476_V	0.544	0.57
293_N	297_P	0.544	0.57
479_E	544_D	0.542	0.57
314_M	353_G	0.542	0.57
183_Y	186_T	0.541	0.57
208_F	250_W	0.541	0.57
211_H	243_P	0.540	0.56
282_Y	555_R	0.540	0.56
328_Y	332_E	0.540	0.56
445_D	522_S	0.539	0.56
301_I	351_V	0.539	0.56
434_Q	523_L	0.539	0.56
466_S	496_V	0.538	0.56
399_W	407_Y	0.538	0.56
177_V	183_Y	0.538	0.56
182_F	201_G	0.537	0.56
445_D	555_R	0.537	0.56
196_P	200_Y	0.537	0.56
296_H	299_G	0.536	0.56
291_S	295_D	0.535	0.56
295_D	381_R	0.535	0.56
211_H	222_R	0.533	0.55
553_A	557_R	0.533	0.55
183_Y	241_S	0.533	0.55
124_L	144_N	0.533	0.55
403_L	444_N	0.532	0.55
134_V	138_N	0.532	0.55
455_V	547_L	0.531	0.55
522_S	550_A	0.530	0.55
404_T	444_N	0.530	0.55
523_L	550_A	0.529	0.55
310_L	316_H	0.529	0.55
129_V	141_S	0.527	0.55
483_V	497_A	0.526	0.54
500_I	509_M	0.525	0.54
171_V	256_M	0.525	0.54
382_R	387_M	0.524	0.54
503_K	506_E	0.522	0.54
538_Q	542_L	0.522	0.54
475_R	548_Y	0.521	0.54
188_P	424_Q	0.521	0.54
548_Y	551_K	0.521	0.54
266_F	281_L	0.520	0.54
450_Q	454_R	0.520	0.54
175_M	206_P	0.520	0.54
520_S	555_R	0.519	0.54
380_I	383_M	0.519	0.54
299_G	337_F	0.519	0.54
143_E	161_L	0.519	0.54
297_P	470_Q	0.518	0.53
471_D	492_E	0.518	0.53
135_S	145_E	0.517	0.53
311_A	319_R	0.517	0.53
335_D	342_V	0.515	0.53
393_S	442_A	0.515	0.53
205_Q	208_F	0.514	0.53
422_L	470_Q	0.513	0.53
394_L	422_L	0.512	0.53
400_H	437_L	0.512	0.53
122_R	143_E	0.510	0.52
320_G	328_Y	0.510	0.52
352_R	357_S	0.510	0.52
161_L	198_R	0.509	0.52
123_T	127_N	0.508	0.52
406_L	463_I	0.508	0.52
128_G	136_E	0.508	0.52
524_G	543_A	0.507	0.52
435_V	476_V	0.507	0.52
411_A	419_L	0.507	0.52
557_R	560_A	0.505	0.52
465_S	503_K	0.504	0.51
444_N	453_D	0.504	0.51
436_D	452_G	0.503	0.51
256_M	259_P	0.503	0.51
423_C	528_S	0.503	0.51
320_G	324_M	0.502	0.51
178_S	187_Q	0.501	0.51
223_W	243_P	0.501	0.51
458_H	509_M	0.501	0.51
362_L	366_W	0.501	0.51
447_F	547_L	0.500	0.51
301_I	355_F	0.500	0.51

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w25A	2	0.727	100	0.546	Contact Map
4j40A	2	0	100	0.575	Contact Map
3ezuA	2	0.5603	100	0.579	Contact Map
4h54A	2	0.4823	100	0.587	Contact Map
4rnhA	2	0.2819	100	0.592	Contact Map
3pjxA	1	0.3138	100	0.592	Contact Map
3ignA	1	0.2943	100	0.605	Contact Map
3mtkA	2	0.2819	100	0.608	Contact Map
3breA	4	0.539	100	0.611	Contact Map
3i5cA	2	0.344	100	0.614	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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