CMOA - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CMOA - tRNA (cmo5U34)-methyltransferase

UniProt:	P76290	Sequences: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHNAGFEHSELWFQCFNFGSLVALKAEDAA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14033
Length:	247 (205)
Sequences:	14949 (11332)
Seq/√Len:	791.5

ECOLI - CMOA UBIE UBIG SMTA YJHP BIOC TAM TEHB CMOB YAFE
BACSU - MENG YBAJ YRRT YXBB YCGJ YODH YQEM YRHH YDAC YXJB
HALSA - Q9HR81 Q9HND6 Q9HMT2 ARSM Q9HRX3 Q9HQ85 Q9HR63 Q9HSK6
SULSO - Q7LXN7 Q97XD7 Q97X57 Q97ZU8 Q97WN4 Q97WT7 Q97YX4 Q97WH3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
59_Q	84_K	3.456	1.00
144_Q	220_N	3.038	1.00
92_P	115_E	3.014	1.00
65_C	87_A	2.908	1.00
151_Y	223_F	2.807	1.00
127_S	155_N	2.794	1.00
64_G	134_T	2.736	1.00
86_I	126_A	2.689	1.00
88_I	116_G	2.545	1.00
61_Y	126_A	2.519	1.00
149_K	152_Q	2.391	1.00
92_P	96_E	2.371	1.00
150_I	160_L	2.359	1.00
95_I	115_E	2.357	1.00
98_C	113_V	2.344	1.00
144_Q	148_D	2.315	1.00
71_T	85_I	2.295	1.00
95_I	113_V	2.262	1.00
84_K	112_D	2.254	1.00
215_K	219_H	2.183	1.00
97_R	100_R	2.177	1.00
21_D	91_S	2.111	1.00
63_L	150_I	2.076	1.00
210_S	213_T	2.064	1.00
86_I	114_I	2.046	1.00
129_V	150_I	1.965	1.00
129_V	154_L	1.960	1.00
144_Q	217_R	1.958	1.00
65_C	71_T	1.920	1.00
154_L	158_G	1.907	1.00
143_R	217_R	1.854	1.00
123_I	126_A	1.848	1.00
102_I	113_V	1.812	1.00
55_Q	58_T	1.763	1.00
59_Q	86_I	1.742	1.00
72_L	102_I	1.728	1.00
149_K	153_G	1.728	1.00
90_N	117_D	1.707	1.00
60_V	74_V	1.705	1.00
76_R	105_Y	1.687	1.00
154_L	160_L	1.678	1.00
71_T	87_A	1.645	1.00
63_L	118_I	1.586	1.00
145_A	148_D	1.565	1.00
60_V	128_M	1.563	1.00
216_A	220_N	1.559	1.00
119_R	142_E	1.533	1.00
138_L	146_L	1.505	1.00
72_L	101_H	1.499	1.00
96_E	99_R	1.499	1.00
118_I	134_T	1.497	1.00
29_P	67_L	1.480	1.00
64_G	131_L	1.456	1.00
21_D	93_A	1.440	1.00
29_P	101_H	1.432	1.00
117_D	120_D	1.431	1.00
86_I	112_D	1.421	1.00
59_Q	155_N	1.411	1.00
122_A	149_K	1.399	1.00
47_G	77_N	1.394	1.00
73_S	76_R	1.391	1.00
116_G	122_A	1.379	1.00
89_D	95_I	1.375	1.00
59_Q	126_A	1.375	1.00
144_Q	221_A	1.361	1.00
123_I	153_G	1.322	1.00
87_A	113_V	1.313	1.00
154_L	223_F	1.305	1.00
142_E	145_A	1.271	1.00
93_A	96_E	1.264	1.00
129_V	153_G	1.257	1.00
59_Q	125_N	1.252	1.00
59_Q	127_S	1.225	1.00
72_L	105_Y	1.205	1.00
58_T	128_M	1.200	1.00
61_Y	129_V	1.164	1.00
216_A	219_H	1.153	1.00
99_R	103_D	1.145	1.00
131_L	134_T	1.145	1.00
20_F	137_F	1.133	1.00
75_R	110_P	1.126	1.00
121_I	149_K	1.067	1.00
58_T	83_C	1.067	1.00
72_L	76_R	1.066	1.00
211_V	230_F	1.066	1.00
146_L	150_I	1.057	1.00
213_T	216_A	1.051	1.00
121_I	153_G	1.045	1.00
73_S	77_N	1.036	1.00
136_Q	164_E	1.036	1.00
68_G	113_V	1.030	1.00
160_L	218_L	1.016	1.00
150_I	154_L	1.001	1.00
76_R	107_A	0.996	1.00
91_S	94_M	0.994	1.00
51_E	77_N	0.987	1.00
88_I	114_I	0.986	1.00
133_F	136_Q	0.985	1.00
125_N	155_N	0.984	1.00
57_G	83_C	0.982	1.00
71_T	111_V	0.982	1.00
135_L	138_L	0.977	1.00
69_A	73_S	0.972	1.00
134_T	138_L	0.967	1.00
26_E	97_R	0.962	1.00
133_F	137_F	0.961	1.00
148_D	152_Q	0.960	1.00
39_Y	42_I	0.956	1.00
17_D	21_D	0.952	1.00
65_C	98_C	0.944	1.00
88_I	121_I	0.943	1.00
215_K	228_L	0.933	1.00
74_V	130_V	0.928	1.00
102_I	111_V	0.927	1.00
133_F	163_S	0.927	1.00
87_A	98_C	0.917	1.00
211_V	215_K	0.911	1.00
69_A	101_H	0.911	1.00
148_D	221_A	0.910	1.00
147_L	221_A	0.899	1.00
96_E	100_R	0.896	1.00
128_M	158_G	0.895	1.00
151_Y	221_A	0.893	1.00
118_I	138_L	0.892	1.00
27_V	30_D	0.890	1.00
63_L	88_I	0.884	1.00
70_A	132_N	0.883	1.00
40_S	44_S	0.877	1.00
89_D	94_M	0.869	1.00
100_R	103_D	0.864	1.00
135_L	162_L	0.859	1.00
102_I	105_Y	0.858	1.00
58_T	127_S	0.858	1.00
164_E	214_H	0.856	1.00
145_A	149_K	0.855	1.00
45_M	48_M	0.852	1.00
95_I	99_R	0.850	1.00
68_G	98_C	0.849	1.00
135_L	146_L	0.849	1.00
147_L	218_L	0.848	1.00
44_S	48_M	0.847	1.00
39_Y	43_I	0.846	1.00
67_L	94_M	0.841	1.00
102_I	107_A	0.837	1.00
132_N	163_S	0.837	1.00
38_G	42_I	0.835	1.00
54_V	58_T	0.835	1.00
100_R	104_A	0.832	1.00
67_L	101_H	0.829	1.00
125_N	152_Q	0.825	1.00
135_L	147_L	0.818	1.00
65_C	89_D	0.816	1.00
182_H	186_R	0.811	1.00
195_I	199_R	0.808	1.00
60_V	85_I	0.807	1.00
107_A	111_V	0.805	1.00
20_F	136_Q	0.801	1.00
114_I	123_I	0.796	1.00
181_H	184_F	0.791	1.00
184_F	188_N	0.784	1.00
176_L	179_N	0.782	1.00
185_K	188_N	0.780	1.00
92_P	99_R	0.778	1.00
75_R	107_A	0.775	1.00
128_M	159_A	0.772	1.00
183_D	186_R	0.769	1.00
189_G	193_L	0.763	1.00
72_L	113_V	0.760	1.00
126_A	153_G	0.758	1.00
123_I	149_K	0.745	1.00
175_E	178_F	0.743	1.00
59_Q	124_E	0.739	1.00
179_N	183_D	0.739	1.00
71_T	113_V	0.731	1.00
51_E	54_V	0.719	1.00
63_L	129_V	0.716	1.00
125_N	153_G	0.715	1.00
167_S	210_S	0.712	1.00
208_T	214_H	0.710	1.00
189_G	195_I	0.709	1.00
41_N	44_S	0.705	1.00
211_V	228_L	0.702	1.00
120_D	149_K	0.701	1.00
25_A	94_M	0.699	1.00
139_E	142_E	0.696	1.00
120_D	145_A	0.694	1.00
36_V	39_Y	0.693	1.00
150_I	162_L	0.693	1.00
147_L	214_H	0.690	1.00
179_N	182_H	0.689	1.00
143_R	209_D	0.688	1.00
86_I	123_I	0.688	1.00
32_I	35_S	0.684	1.00
54_V	128_M	0.684	1.00
189_G	192_E	0.683	1.00
82_N	85_I	0.680	1.00
102_I	106_K	0.672	1.00
48_M	51_E	0.671	1.00
46_I	49_L	0.670	1.00
99_R	112_D	0.666	1.00
212_E	215_K	0.666	1.00
184_F	187_A	0.666	1.00
217_R	221_A	0.662	1.00
64_G	90_N	0.661	1.00
186_R	189_G	0.660	1.00
217_R	220_N	0.657	1.00
123_I	152_Q	0.652	1.00
18_W	23_R	0.650	1.00
60_V	83_C	0.646	1.00
36_V	40_S	0.646	1.00
162_L	218_L	0.645	1.00
42_I	46_I	0.641	1.00
93_A	97_R	0.641	1.00
65_C	95_I	0.639	1.00
124_E	152_Q	0.636	1.00
181_H	186_R	0.634	1.00
31_M	34_R	0.629	1.00
99_R	113_V	0.629	1.00
61_Y	153_G	0.625	1.00
180_M	183_D	0.622	1.00
147_L	217_R	0.620	1.00
95_I	98_C	0.614	1.00
131_L	160_L	0.614	1.00
72_L	75_R	0.610	1.00
174_G	178_F	0.610	1.00
63_L	146_L	0.609	1.00
90_N	115_E	0.607	1.00
97_R	101_H	0.605	1.00
62_D	65_C	0.604	1.00
33_Q	40_S	0.602	1.00
135_L	214_H	0.600	1.00
17_D	115_E	0.600	1.00
70_A	73_S	0.598	1.00
72_L	107_A	0.596	1.00
70_A	130_V	0.595	1.00
199_R	202_L	0.594	1.00
94_M	133_F	0.593	1.00
151_Y	154_L	0.586	1.00
42_I	45_M	0.584	1.00
49_L	229_W	0.584	1.00
60_V	130_V	0.579	1.00
160_L	223_F	0.579	1.00
48_M	52_R	0.579	1.00
62_D	70_A	0.577	1.00
47_G	51_E	0.575	1.00
37_P	41_N	0.574	1.00
148_D	220_N	0.573	1.00
101_H	104_A	0.572	1.00
45_M	229_W	0.570	1.00
129_V	158_G	0.568	1.00
47_G	50_A	0.567	1.00
64_G	138_L	0.566	1.00
131_L	138_L	0.564	1.00
194_E	197_Q	0.561	1.00
183_D	187_A	0.559	1.00
213_T	217_R	0.558	1.00
48_M	77_N	0.556	1.00
24_V	27_V	0.556	1.00
46_I	50_A	0.553	1.00
17_D	90_N	0.553	1.00
49_L	227_E	0.553	1.00
103_D	106_K	0.551	1.00
67_L	97_R	0.550	1.00
45_M	49_L	0.550	1.00
50_A	128_M	0.550	1.00
116_G	121_I	0.545	1.00
147_L	162_L	0.543	1.00
25_A	29_P	0.543	1.00
29_P	97_R	0.543	1.00
152_Q	156_P	0.542	1.00
137_F	164_E	0.542	1.00
195_I	198_K	0.541	1.00
173_V	176_L	0.540	1.00
131_L	164_E	0.538	1.00
64_G	118_I	0.536	1.00
122_A	153_G	0.536	1.00
65_C	113_V	0.534	1.00
136_Q	165_K	0.534	1.00
212_E	216_A	0.533	1.00
192_E	195_I	0.533	1.00
44_S	73_S	0.532	1.00
43_I	46_I	0.532	1.00
62_D	130_V	0.530	1.00
40_S	73_S	0.529	1.00
67_L	89_D	0.527	1.00
62_D	85_I	0.527	1.00
71_T	75_R	0.526	1.00
191_S	195_I	0.525	1.00
133_F	164_E	0.524	1.00
219_H	225_H	0.523	1.00
29_P	32_I	0.520	1.00
132_N	136_Q	0.518	1.00
119_R	146_L	0.516	1.00
133_F	165_K	0.515	1.00
40_S	43_I	0.512	1.00
75_R	111_V	0.511	1.00
28_F	67_L	0.510	1.00
197_Q	200_S	0.507	1.00
38_G	41_N	0.506	1.00
137_F	165_K	0.505	1.00
20_F	24_V	0.505	1.00
131_L	162_L	0.505	1.00
193_L	197_Q	0.503	1.00
118_I	146_L	0.502	1.00
190_Y	193_L	0.502	1.00
69_A	72_L	0.501	1.00
202_L	205_V	0.501	1.00
35_S	137_F	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4gekA	2	0.9352	100	0.324	Contact Map
3dtnA	2	0.9028	100	0.379	Contact Map
4obxA	2	0.8745	100	0.386	Contact Map
3bxoA	2	0.8664	100	0.426	Contact Map
4pneA	2	0.8583	100	0.432	Contact Map
1y8cA	1	0.8866	100	0.435	Contact Map
1wznA	4	0.8583	100	0.436	Contact Map
3pfgA	2	0.8866	100	0.44	Contact Map
3hnrA	1	0.7652	100	0.442	Contact Map
4kdcA	1	0.7976	100	0.443	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.