RSMF - ECOLI - GREMLIN Contacts

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RSMF - Ribosomal RNA small subunit methyltransferase F

UniProt:	P76273	Sequences: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKDREAGQIRQAATGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIALASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTGNA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14023
Length:	479 (425)
Sequences:	1666 (1339)
Seq/√Len:	65.0

ECOLI - RSMF RSMB
BACSU - RSMB
HALSA - Q9HRX7
SULSO - Q980N8 Q980Z5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
270_E	309_R	5.667	1.00
241_T	309_R	4.890	1.00
258_C	308_L	4.829	1.00
191_I	236_L	4.629	1.00
270_E	311_T	4.615	1.00
230_D	264_T	4.292	1.00
132_T	162_I	3.865	1.00
132_T	147_A	3.830	1.00
233_F	269_V	3.789	1.00
119_Q	190_A	3.784	1.00
108_V	135_I	3.681	1.00
241_T	307_R	3.553	1.00
290_F	304_F	3.486	1.00
125_A	193_L	3.252	1.00
226_R	260_W	3.246	1.00
26_F	30_L	3.195	1.00
15_Q	252_E	3.107	1.00
10_D	14_T	3.080	1.00
136_S	167_I	3.063	1.00
271_F	306_A	3.043	1.00
15_Q	250_N	2.846	1.00
229_I	261_L	2.812	1.00
273_P	289_G	2.811	1.00
65_T	299_D	2.671	1.00
233_F	261_L	2.436	1.00
25_S	296_Q	2.418	1.00
132_T	145_I	2.415	1.00
91_E	446_Q	2.382	1.00
243_V	307_R	2.347	1.00
111_L	115_G	2.321	1.00
144_A	187_M	2.307	1.00
120_R	237_R	2.262	1.00
175_F	179_V	2.244	1.00
261_L	265_Y	2.216	1.00
31_A	35_R	2.207	1.00
167_I	170_V	2.164	1.00
117_A	142_E	2.157	1.00
200_E	248_T	2.118	1.00
11_A	215_P	2.081	1.00
272_L	309_R	2.069	1.00
110_A	305_V	2.052	1.00
417_T	420_E	2.051	1.00
135_I	192_L	2.036	1.00
189_D	237_R	2.007	1.00
104_S	303_F	1.973	1.00
230_D	265_Y	1.951	1.00
423_E	428_R	1.943	1.00
45_T	137_A	1.932	1.00
293_V	298_Y	1.910	1.00
236_L	242_L	1.904	1.00
110_A	274_L	1.902	1.00
193_L	229_I	1.857	1.00
107_P	134_Q	1.826	1.00
28_D	31_A	1.822	1.00
262_K	271_F	1.790	1.00
32_A	35_R	1.782	1.00
177_G	231_S	1.771	1.00
261_L	269_V	1.766	1.00
251_Q	256_A	1.754	1.00
35_R	299_D	1.749	1.00
363_E	389_E	1.727	0.99
41_I	97_F	1.726	0.99
363_E	386_K	1.721	0.99
114_D	135_I	1.711	0.99
31_A	34_Q	1.703	0.99
43_V	53_F	1.695	0.99
53_F	57_T	1.687	0.99
27_D	31_A	1.679	0.99
180_F	235_A	1.666	0.99
249_L	302_G	1.665	0.99
255_E	292_H	1.649	0.99
272_L	307_R	1.641	0.99
212_N	217_S	1.639	0.99
155_V	381_S	1.613	0.99
178_R	227_E	1.608	0.99
40_S	102_A	1.600	0.99
107_P	192_L	1.598	0.99
115_G	139_M	1.579	0.99
124_V	232_A	1.576	0.99
87_G	164_R	1.565	0.99
280_G	283_K	1.565	0.99
115_G	138_R	1.562	0.99
229_I	242_L	1.562	0.99
162_I	167_I	1.551	0.99
191_I	235_A	1.544	0.99
41_I	76_I	1.541	0.99
339_Q	343_A	1.538	0.99
286_T	289_G	1.514	0.99
236_L	310_K	1.512	0.99
238_P	311_T	1.503	0.99
87_G	92_H	1.498	0.99
29_F	296_Q	1.496	0.99
108_V	134_Q	1.485	0.98
193_L	228_L	1.479	0.98
13_L	26_F	1.477	0.98
277_L	280_G	1.468	0.98
285_L	288_E	1.464	0.98
340_I	343_A	1.462	0.98
287_E	290_F	1.456	0.98
279_P	283_K	1.450	0.98
402_V	442_L	1.450	0.98
42_R	133_T	1.443	0.98
241_T	272_L	1.441	0.98
254_N	294_F	1.421	0.98
106_L	293_V	1.410	0.98
173_T	180_F	1.407	0.98
69_W	102_A	1.400	0.98
92_H	164_R	1.398	0.98
415_E	446_Q	1.394	0.98
134_Q	137_A	1.389	0.98
278_F	281_A	1.387	0.98
111_L	192_L	1.365	0.97
219_Q	252_E	1.359	0.97
177_G	228_L	1.352	0.97
279_P	282_N	1.341	0.97
349_L	352_D	1.335	0.97
388_A	395_Y	1.327	0.97
121_V	135_I	1.323	0.97
115_G	119_Q	1.311	0.97
265_Y	269_V	1.310	0.97
12_F	33_C	1.303	0.96
332_V	335_R	1.300	0.96
41_I	99_I	1.297	0.96
175_F	378_V	1.278	0.96
336_E	339_Q	1.278	0.96
70_C	109_A	1.271	0.96
176_D	227_E	1.270	0.96
110_A	291_L	1.269	0.96
267_D	310_K	1.267	0.96
45_T	50_V	1.266	0.96
230_D	260_W	1.258	0.96
220_E	224_T	1.257	0.96
120_R	187_M	1.252	0.96
233_F	267_D	1.249	0.95
256_A	284_A	1.241	0.95
115_G	134_Q	1.239	0.95
181_G	231_S	1.235	0.95
214_S	218_N	1.231	0.95
231_S	234_H	1.230	0.95
209_A	221_I	1.221	0.95
147_A	192_L	1.220	0.95
259_L	263_E	1.212	0.95
128_P	131_K	1.204	0.94
290_F	306_A	1.199	0.94
233_F	265_Y	1.195	0.94
226_R	257_V	1.193	0.94
114_D	241_T	1.188	0.94
422_E	426_R	1.188	0.94
181_G	234_H	1.175	0.94
122_M	146_L	1.170	0.94
284_A	287_E	1.169	0.94
15_Q	19_A	1.164	0.93
217_S	220_E	1.159	0.93
271_F	308_L	1.149	0.93
146_L	188_F	1.149	0.93
147_A	162_I	1.142	0.93
149_E	209_A	1.135	0.92
271_F	289_G	1.131	0.92
176_D	231_S	1.116	0.92
10_D	13_L	1.112	0.92
38_R	299_D	1.106	0.91
271_F	290_F	1.105	0.91
421_A	445_F	1.104	0.91
19_A	252_E	1.100	0.91
17_R	26_F	1.096	0.91
134_Q	138_R	1.091	0.91
359_Q	362_K	1.082	0.91
103_S	300_C	1.082	0.91
181_G	235_A	1.082	0.91
65_T	77_E	1.081	0.91
252_E	256_A	1.072	0.90
111_L	135_I	1.071	0.90
131_K	194_D	1.068	0.90
385_I	404_A	1.060	0.90
73_G	105_M	1.058	0.90
162_I	170_V	1.054	0.89
105_M	125_A	1.053	0.89
372_E	376_G	1.052	0.89
17_R	27_D	1.051	0.89
160_A	164_R	1.046	0.89
338_G	343_A	1.046	0.89
260_W	263_E	1.042	0.89
333_K	340_I	1.035	0.89
415_E	444_T	1.029	0.88
128_P	194_D	1.021	0.88
202_V	301_E	1.017	0.88
149_E	160_A	1.016	0.88
270_E	289_G	1.015	0.88
16_M	26_F	1.009	0.87
269_V	310_K	1.009	0.87
154_R	194_D	1.008	0.87
49_S	52_D	1.006	0.87
129_G	194_D	1.006	0.87
233_F	254_N	1.005	0.87
218_N	221_I	1.004	0.87
124_V	193_L	1.003	0.87
69_W	73_G	1.001	0.87
257_V	260_W	0.999	0.87
343_A	346_G	0.996	0.87
25_S	28_D	0.995	0.86
256_A	259_L	0.993	0.86
29_F	33_C	0.989	0.86
349_L	353_E	0.988	0.86
212_N	224_T	0.986	0.86
260_W	264_T	0.984	0.86
136_S	169_N	0.982	0.86
121_V	190_A	0.979	0.86
131_K	154_R	0.976	0.85
335_R	339_Q	0.976	0.85
119_Q	139_M	0.973	0.85
11_A	14_T	0.972	0.85
191_I	232_A	0.972	0.85
162_I	376_G	0.964	0.85
114_D	307_R	0.961	0.85
362_K	389_E	0.961	0.85
107_P	111_L	0.959	0.84
155_V	172_L	0.959	0.84
58_A	62_W	0.954	0.84
274_L	307_R	0.954	0.84
92_H	149_E	0.954	0.84
117_A	140_N	0.949	0.84
217_S	224_T	0.949	0.84
69_W	97_F	0.948	0.84
341_R	344_A	0.948	0.84
259_L	290_F	0.944	0.83
238_P	313_A	0.942	0.83
132_T	139_M	0.941	0.83
13_L	30_L	0.940	0.83
91_E	96_L	0.937	0.83
419_Q	423_E	0.935	0.83
243_V	305_V	0.934	0.83
67_I	102_A	0.924	0.82
145_I	162_I	0.923	0.82
98_Y	161_N	0.923	0.82
70_C	75_W	0.923	0.82
388_A	398_Q	0.922	0.82
337_A	341_R	0.922	0.82
44_N	47_K	0.918	0.82
128_P	154_R	0.918	0.82
386_K	389_E	0.916	0.82
157_V	224_T	0.911	0.81
242_L	261_L	0.910	0.81
86_L	97_F	0.907	0.81
101_E	204_R	0.904	0.81
116_N	119_Q	0.901	0.80
155_V	174_H	0.898	0.80
146_L	173_T	0.897	0.80
129_G	154_R	0.896	0.80
105_M	213_W	0.890	0.80
14_T	18_E	0.879	0.79
171_A	380_F	0.878	0.79
342_Q	345_T	0.877	0.79
271_F	304_F	0.876	0.79
133_T	162_I	0.869	0.78
154_R	247_C	0.869	0.78
14_T	17_R	0.866	0.78
126_A	174_H	0.865	0.78
194_D	247_C	0.865	0.78
337_A	340_I	0.864	0.78
47_K	73_G	0.862	0.77
202_V	205_K	0.861	0.77
276_D	280_G	0.860	0.77
43_V	74_F	0.857	0.77
131_K	247_C	0.857	0.77
25_S	297_I	0.854	0.77
233_F	310_K	0.852	0.77
269_V	308_L	0.849	0.76
15_Q	251_Q	0.848	0.76
103_S	301_E	0.848	0.76
229_I	260_W	0.846	0.76
332_V	336_E	0.846	0.76
266_P	269_V	0.846	0.76
150_F	176_D	0.845	0.76
44_N	166_G	0.844	0.76
326_N	333_K	0.835	0.75
50_V	54_L	0.835	0.75
13_L	17_R	0.833	0.75
16_M	97_F	0.828	0.75
124_V	177_G	0.828	0.75
27_D	335_R	0.827	0.74
260_W	265_Y	0.823	0.74
374_L	377_K	0.822	0.74
92_H	224_T	0.819	0.74
356_R	369_V	0.819	0.74
361_D	364_L	0.817	0.74
53_F	58_A	0.816	0.74
109_A	243_V	0.816	0.74
333_K	337_A	0.814	0.73
68_P	73_G	0.811	0.73
128_P	247_C	0.810	0.73
67_I	105_M	0.806	0.73
415_E	447_H	0.802	0.72
412_N	437_V	0.801	0.72
16_M	99_I	0.797	0.72
418_P	446_Q	0.796	0.72
93_L	160_A	0.791	0.71
106_L	305_V	0.790	0.71
444_T	449_P	0.790	0.71
320_P	339_Q	0.781	0.70
96_L	448_Q	0.780	0.70
283_K	288_E	0.780	0.70
391_H	396_R	0.779	0.70
109_A	138_R	0.779	0.70
205_K	213_W	0.778	0.70
20_M	26_F	0.777	0.70
149_E	216_E	0.776	0.70
340_I	344_A	0.774	0.70
341_R	347_V	0.773	0.69
45_T	48_I	0.773	0.69
277_L	282_N	0.773	0.69
181_G	228_L	0.772	0.69
108_V	138_R	0.772	0.69
98_Y	133_T	0.771	0.69
328_P	332_V	0.771	0.69
234_H	265_Y	0.769	0.69
221_I	224_T	0.768	0.69
287_E	308_L	0.767	0.69
180_F	188_F	0.762	0.68
243_V	262_K	0.761	0.68
347_V	353_E	0.761	0.68
329_F	333_K	0.758	0.68
129_G	247_C	0.756	0.68
133_T	161_N	0.754	0.67
224_T	228_L	0.754	0.67
208_D	212_N	0.754	0.67
48_I	56_L	0.752	0.67
87_G	205_K	0.752	0.67
226_R	264_T	0.751	0.67
347_V	350_N	0.749	0.67
278_F	282_N	0.749	0.67
181_G	379_R	0.746	0.67
213_W	250_N	0.743	0.66
202_V	303_F	0.736	0.66
379_R	431_Y	0.735	0.66
20_M	25_S	0.734	0.65
140_N	168_S	0.733	0.65
12_F	29_F	0.730	0.65
274_L	291_L	0.727	0.65
16_M	19_A	0.722	0.64
134_Q	165_C	0.722	0.64
70_C	73_G	0.719	0.64
75_W	299_D	0.716	0.63
174_H	381_S	0.716	0.63
69_W	421_A	0.714	0.63
45_T	56_L	0.714	0.63
204_R	301_E	0.712	0.63
397_W	401_A	0.710	0.63
390_T	395_Y	0.707	0.62
149_E	164_R	0.704	0.62
351_W	354_N	0.704	0.62
332_V	343_A	0.702	0.62
238_P	248_T	0.700	0.62
200_E	301_E	0.697	0.61
18_E	27_D	0.694	0.61
184_V	235_A	0.694	0.61
412_N	416_L	0.692	0.61
327_F	330_S	0.692	0.61
258_C	290_F	0.692	0.61
111_L	190_A	0.692	0.61
355_L	358_W	0.690	0.61
14_T	144_A	0.685	0.60
333_K	344_A	0.684	0.60
321_K	326_N	0.683	0.60
126_A	131_K	0.680	0.59
52_D	55_Q	0.680	0.59
331_P	341_R	0.679	0.59
339_Q	344_A	0.678	0.59
159_H	172_L	0.678	0.59
209_A	214_S	0.678	0.59
262_K	266_P	0.678	0.59
146_L	171_A	0.678	0.59
203_V	209_A	0.677	0.59
312_Q	346_G	0.677	0.59
326_N	329_F	0.677	0.59
160_A	165_C	0.673	0.59
38_R	192_L	0.672	0.59
93_L	425_Y	0.672	0.59
217_S	221_I	0.671	0.58
98_Y	166_G	0.669	0.58
338_G	342_Q	0.669	0.58
69_W	402_V	0.666	0.58
204_R	384_G	0.666	0.58
348_G	355_L	0.666	0.58
346_G	349_L	0.665	0.58
155_V	159_H	0.664	0.58
43_V	54_L	0.663	0.58
382_R	385_I	0.663	0.58
76_I	99_I	0.662	0.57
101_E	301_E	0.662	0.57
69_W	101_E	0.662	0.57
334_D	342_Q	0.659	0.57
135_I	190_A	0.657	0.57
54_L	66_P	0.657	0.57
194_D	245_S	0.656	0.57
214_S	221_I	0.654	0.57
233_F	272_L	0.652	0.56
277_L	281_A	0.652	0.56
158_L	245_S	0.651	0.56
420_E	432_P	0.649	0.56
72_E	138_R	0.648	0.56
321_K	356_R	0.647	0.56
149_E	224_T	0.647	0.56
50_V	53_F	0.647	0.56
158_L	247_C	0.647	0.56
40_S	303_F	0.646	0.56
284_A	288_E	0.646	0.56
171_A	371_I	0.644	0.55
333_K	341_R	0.643	0.55
102_A	303_F	0.643	0.55
108_V	115_G	0.642	0.55
130_S	161_N	0.639	0.55
321_K	328_P	0.639	0.55
223_A	227_E	0.637	0.55
87_G	160_A	0.636	0.54
335_R	414_F	0.636	0.54
97_F	130_S	0.636	0.54
342_Q	351_W	0.636	0.54
388_A	401_A	0.635	0.54
66_P	73_G	0.635	0.54
352_D	357_L	0.635	0.54
334_D	337_A	0.634	0.54
342_Q	356_R	0.634	0.54
28_D	338_G	0.633	0.54
206_D	209_A	0.631	0.54
147_A	254_N	0.631	0.54
160_A	293_V	0.626	0.53
238_P	241_T	0.626	0.53
354_N	357_L	0.626	0.53
264_T	419_Q	0.626	0.53
364_L	390_T	0.624	0.53
400_E	403_I	0.624	0.53
107_P	160_A	0.623	0.53
106_L	110_A	0.621	0.53
276_D	279_P	0.620	0.53
107_P	151_S	0.620	0.53
340_I	356_R	0.620	0.53
424_W	427_G	0.619	0.52
174_H	217_S	0.618	0.52
336_E	344_A	0.618	0.52
146_L	180_F	0.618	0.52
352_D	356_R	0.618	0.52
266_P	311_T	0.616	0.52
251_Q	259_L	0.614	0.52
432_P	436_P	0.613	0.52
193_L	224_T	0.613	0.52
92_H	209_A	0.610	0.51
18_E	28_D	0.610	0.51
67_I	73_G	0.609	0.51
362_K	440_D	0.609	0.51
339_Q	342_Q	0.608	0.51
128_P	245_S	0.608	0.51
131_K	245_S	0.607	0.51
331_P	334_D	0.607	0.51
90_A	425_Y	0.606	0.51
347_V	360_R	0.603	0.51
386_K	400_E	0.603	0.51
16_M	200_E	0.602	0.50
123_D	154_R	0.601	0.50
333_K	336_E	0.600	0.50
157_V	160_A	0.599	0.50
94_S	97_F	0.599	0.50
337_A	342_Q	0.599	0.50
291_L	305_V	0.598	0.50
314_I	318_P	0.598	0.50
177_G	229_I	0.597	0.50
54_L	64_L	0.595	0.50
119_Q	140_N	0.594	0.50
67_I	75_W	0.594	0.50
209_A	217_S	0.594	0.50
47_K	169_N	0.594	0.50
416_L	420_E	0.593	0.49
149_E	221_I	0.593	0.49
130_S	202_V	0.593	0.49
164_R	399_H	0.593	0.49
184_V	187_M	0.592	0.49
284_A	289_G	0.592	0.49
90_A	94_S	0.591	0.49
132_T	193_L	0.591	0.49
431_Y	434_A	0.591	0.49
275_G	282_N	0.591	0.49
104_S	194_D	0.589	0.49
183_A	378_V	0.589	0.49
168_S	404_A	0.588	0.49
148_N	196_P	0.587	0.49
18_E	25_S	0.587	0.49
148_N	189_D	0.587	0.49
180_F	308_L	0.586	0.49
125_A	131_K	0.586	0.49
330_S	334_D	0.585	0.49
320_P	430_V	0.584	0.48
127_A	194_D	0.582	0.48
50_V	74_F	0.582	0.48
155_V	224_T	0.582	0.48
326_N	343_A	0.582	0.48
148_N	188_F	0.578	0.48
16_M	41_I	0.578	0.48
73_G	94_S	0.578	0.48
114_D	138_R	0.578	0.48
334_D	348_G	0.578	0.48
104_S	202_V	0.577	0.48
86_L	157_V	0.577	0.48
413_A	444_T	0.576	0.47
357_L	360_R	0.576	0.47
67_I	155_V	0.576	0.47
149_E	157_V	0.575	0.47
226_R	265_Y	0.575	0.47
46_L	167_I	0.574	0.47
392_N	396_R	0.574	0.47
155_V	177_G	0.574	0.47
196_P	240_G	0.573	0.47
187_M	370_G	0.572	0.47
239_G	310_K	0.571	0.47
412_N	443_V	0.569	0.47
122_M	188_F	0.569	0.47
331_P	337_A	0.568	0.47
101_E	303_F	0.567	0.46
107_P	243_V	0.567	0.46
9_P	16_M	0.567	0.46
230_D	433_Q	0.566	0.46
27_D	35_R	0.566	0.46
104_S	131_K	0.566	0.46
8_F	207_P	0.566	0.46
123_D	129_G	0.566	0.46
337_A	344_A	0.565	0.46
48_I	96_L	0.565	0.46
62_W	84_L	0.564	0.46
186_E	310_K	0.564	0.46
129_G	245_S	0.563	0.46
11_A	423_E	0.563	0.46
118_P	141_N	0.563	0.46
107_P	143_G	0.563	0.46
104_S	163_S	0.562	0.46
120_R	371_I	0.560	0.46
207_P	420_E	0.559	0.45
124_V	145_I	0.559	0.45
75_W	102_A	0.557	0.45
174_H	379_R	0.556	0.45
224_T	229_I	0.555	0.45
264_T	308_L	0.555	0.45
218_N	250_N	0.555	0.45
154_R	245_S	0.554	0.45
126_A	245_S	0.554	0.45
423_E	426_R	0.554	0.45
36_P	334_D	0.553	0.45
92_H	160_A	0.552	0.45
42_R	213_W	0.552	0.45
76_I	79_D	0.551	0.45
343_A	347_V	0.549	0.44
10_D	116_N	0.549	0.44
218_N	304_F	0.546	0.44
148_N	205_K	0.546	0.44
200_E	250_N	0.545	0.44
406_A	409_D	0.543	0.44
256_A	287_E	0.543	0.44
127_A	131_K	0.543	0.44
12_F	213_W	0.543	0.44
116_N	190_A	0.543	0.44
248_T	400_E	0.543	0.44
338_G	341_R	0.542	0.44
222_A	226_R	0.542	0.44
334_D	338_G	0.541	0.43
17_R	22_S	0.541	0.43
192_L	307_R	0.540	0.43
87_G	99_I	0.540	0.43
257_V	262_K	0.538	0.43
160_A	214_S	0.538	0.43
280_G	291_L	0.537	0.43
195_A	221_I	0.537	0.43
38_R	303_F	0.537	0.43
92_H	399_H	0.537	0.43
316_A	320_P	0.536	0.43
295_P	302_G	0.536	0.43
337_A	343_A	0.536	0.43
259_L	285_L	0.534	0.43
124_V	132_T	0.534	0.43
430_V	443_V	0.534	0.43
203_V	301_E	0.533	0.42
108_V	111_L	0.533	0.42
125_A	129_G	0.532	0.42
178_R	231_S	0.531	0.42
76_I	86_L	0.531	0.42
55_Q	58_A	0.531	0.42
224_T	227_E	0.530	0.42
34_Q	333_K	0.529	0.42
237_R	310_K	0.529	0.42
115_G	125_A	0.528	0.42
104_S	129_G	0.527	0.42
41_I	64_L	0.526	0.42
291_L	321_K	0.524	0.41
47_K	166_G	0.523	0.41
238_P	314_I	0.523	0.41
212_N	421_A	0.522	0.41
13_L	65_T	0.522	0.41
92_H	107_P	0.520	0.41
21_P	203_V	0.520	0.41
294_F	399_H	0.520	0.41
421_A	425_Y	0.519	0.41
416_L	419_Q	0.519	0.41
8_F	12_F	0.518	0.41
171_A	374_L	0.516	0.41
101_E	300_C	0.516	0.41
330_S	356_R	0.516	0.41
15_Q	18_E	0.513	0.40
16_M	248_T	0.513	0.40
173_T	184_V	0.513	0.40
335_R	338_G	0.513	0.40
263_E	285_L	0.513	0.40
31_A	320_P	0.512	0.40
97_F	105_M	0.512	0.40
232_A	235_A	0.512	0.40
123_D	131_K	0.512	0.40
331_P	336_E	0.511	0.40
144_A	171_A	0.511	0.40
407_S	415_E	0.509	0.40
111_L	243_V	0.509	0.40
351_W	355_L	0.509	0.40
202_V	300_C	0.509	0.40
86_L	89_T	0.508	0.40
152_A	156_K	0.508	0.40
111_L	116_N	0.507	0.40
246_T	253_E	0.507	0.40
65_T	433_Q	0.507	0.40
104_S	128_P	0.506	0.39
332_V	354_N	0.506	0.39
29_F	103_S	0.506	0.39
87_G	221_I	0.505	0.39
341_R	350_N	0.504	0.39
284_A	317_L	0.504	0.39
114_D	190_A	0.503	0.39
164_R	190_A	0.503	0.39
386_K	398_Q	0.503	0.39
168_S	409_D	0.502	0.39
126_A	194_D	0.502	0.39
258_C	447_H	0.502	0.39
101_E	295_P	0.502	0.39
20_M	294_F	0.501	0.39
136_S	165_C	0.501	0.39
98_Y	301_E	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2frxA	1	0.9499	100	0.312	Contact Map
3m4xA	1	0.8956	100	0.361	Contact Map
3m6wA	2	0.9228	100	0.384	Contact Map
1ixkA	1	0.6117	100	0.553	Contact Map
2yxlA	1	0.62	100	0.563	Contact Map
2b9eA	1	0.5282	100	0.58	Contact Map
1sqgA	1	0.6054	100	0.583	Contact Map
3ajdA	1	0.5198	100	0.621	Contact Map
4fzvA	1	0.6326	100	0.636	Contact Map
2vdvE	2	0.4259	99.9	0.829	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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