KDGR - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

KDGR - Transcriptional regulator KdgR

UniProt:	P76268	Sequences: MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG14018
Length:	263 (246)
Sequences:	12791 (9329)
Seq/√Len:	594.8

ECOLI - KDGR ALLR YIAJ ICLR MHPR RHMR YAGI YJHI
BACSU - KIPR
HALSA - Q9HHM8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
103_L	244_M	3.223	1.00
16_V	19_V	3.196	1.00
111_G	147_I	2.835	1.00
17_L	58_L	2.819	1.00
96_Q	248_A	2.805	1.00
189_Q	193_Q	2.671	1.00
24_Q	75_K	2.570	1.00
94_D	122_H	2.418	1.00
149_K	186_V	2.412	1.00
20_F	60_Y	2.338	1.00
161_K	184_L	2.332	1.00
117_S	139_R	2.189	1.00
149_K	201_E	2.161	1.00
96_Q	251_K	2.149	1.00
26_L	61_V	2.071	1.00
98_R	124_I	2.056	1.00
155_R	159_E	2.045	1.00
106_E	232_R	2.036	1.00
21_G	58_L	2.003	1.00
211_V	245_L	1.946	1.00
154_W	214_F	1.916	1.00
113_L	142_L	1.885	1.00
96_Q	255_Q	1.868	1.00
199_N	207_R	1.851	1.00
211_V	249_A	1.820	1.00
207_R	230_T	1.814	1.00
198_D	208_C	1.800	1.00
64_E	67_S	1.776	1.00
99_E	251_K	1.769	1.00
242_V	246_H	1.751	1.00
62_A	71_S	1.747	1.00
22_I	37_L	1.736	1.00
180_T	184_L	1.722	1.00
99_E	103_L	1.705	1.00
24_Q	58_L	1.698	1.00
25_A	41_V	1.681	1.00
179_S	182_A	1.671	1.00
93_A	252_I	1.671	1.00
25_A	32_I	1.670	1.00
25_A	40_R	1.658	1.00
101_S	108_I	1.648	1.00
211_V	246_H	1.639	1.00
52_L	61_V	1.633	1.00
200_E	230_T	1.625	1.00
25_A	37_L	1.614	1.00
228_F	233_F	1.591	1.00
226_I	241_Y	1.580	1.00
32_I	40_R	1.570	1.00
52_L	70_Y	1.567	1.00
195_Y	242_V	1.566	1.00
186_V	189_Q	1.554	1.00
33_G	36_E	1.538	1.00
31_E	71_S	1.525	1.00
160_V	184_L	1.520	1.00
190_V	196_G	1.509	1.00
96_Q	99_E	1.506	1.00
104_T	244_M	1.506	1.00
173_T	176_T	1.505	1.00
200_E	205_G	1.500	1.00
156_D	159_E	1.489	1.00
43_M	48_V	1.486	1.00
37_L	48_V	1.460	1.00
244_M	247_T	1.460	1.00
31_E	69_K	1.455	1.00
118_I	151_L	1.436	1.00
75_K	78_E	1.409	1.00
125_D	131_R	1.402	1.00
161_K	180_T	1.397	1.00
93_A	110_L	1.369	1.00
214_F	253_S	1.368	1.00
90_I	122_H	1.368	1.00
118_I	142_L	1.361	1.00
56_K	61_V	1.354	1.00
100_L	244_M	1.352	1.00
101_S	124_I	1.340	1.00
56_K	63_Q	1.332	1.00
20_F	58_L	1.331	1.00
29_E	32_I	1.326	1.00
24_Q	60_Y	1.323	1.00
249_A	253_S	1.316	1.00
26_L	32_I	1.315	1.00
237_R	240_E	1.304	1.00
116_D	166_G	1.303	1.00
247_T	251_K	1.297	1.00
26_L	31_E	1.291	1.00
64_E	71_S	1.288	1.00
97_M	110_L	1.270	1.00
94_D	98_R	1.263	1.00
177_I	186_V	1.250	1.00
49_Y	53_Q	1.245	1.00
100_L	248_A	1.235	1.00
29_E	40_R	1.234	1.00
44_S	47_T	1.231	1.00
157_R	184_L	1.230	1.00
38_S	48_V	1.221	1.00
187_L	190_V	1.209	1.00
165_E	180_T	1.209	1.00
157_R	161_K	1.194	1.00
37_L	52_L	1.191	1.00
153_A	190_V	1.178	1.00
214_F	220_V	1.172	1.00
113_L	155_R	1.143	1.00
144_S	172_S	1.137	1.00
154_W	212_P	1.129	1.00
154_W	220_V	1.128	1.00
175_R	200_E	1.121	1.00
246_H	250_R	1.119	1.00
111_G	118_I	1.117	1.00
33_G	69_K	1.105	1.00
34_I	49_Y	1.104	1.00
211_V	242_V	1.103	1.00
104_T	241_Y	1.100	1.00
157_R	160_V	1.092	1.00
35_T	39_Q	1.089	1.00
144_S	176_T	1.081	1.00
17_L	54_T	1.074	1.00
17_L	57_T	1.069	1.00
113_L	116_D	1.068	1.00
251_K	255_Q	1.067	1.00
98_R	102_R	1.057	1.00
160_V	191_R	1.056	1.00
110_L	222_A	1.056	1.00
147_I	223_G	1.048	1.00
112_A	222_A	1.042	1.00
164_L	180_T	1.037	1.00
97_M	108_I	1.031	1.00
99_E	248_A	1.025	1.00
110_L	213_V	1.022	1.00
34_I	38_S	1.019	1.00
224_L	252_I	1.019	1.00
104_T	226_I	1.015	1.00
143_Y	176_T	1.015	1.00
243_A	247_T	1.014	1.00
13_V	54_T	1.012	1.00
157_R	188_D	1.012	1.00
76_L	83_A	1.010	1.00
36_E	39_Q	1.004	1.00
60_Y	79_L	1.000	1.00
171_R	178_T	0.998	1.00
159_E	162_Q	0.990	1.00
161_K	165_E	0.984	1.00
215_D	219_V	0.979	1.00
250_R	254_A	0.973	1.00
111_G	120_Y	0.972	1.00
234_S	237_R	0.970	1.00
12_S	57_T	0.968	1.00
114_D	139_R	0.963	1.00
145_T	148_G	0.951	1.00
94_D	124_I	0.948	1.00
103_L	247_T	0.946	1.00
146_A	208_C	0.941	1.00
35_T	45_K	0.938	1.00
31_E	64_E	0.936	1.00
119_V	139_R	0.935	1.00
174_E	204_E	0.929	1.00
190_V	193_Q	0.921	1.00
89_L	222_A	0.912	1.00
108_I	226_I	0.911	1.00
212_P	220_V	0.907	1.00
92_S	255_Q	0.905	1.00
23_L	76_L	0.903	1.00
14_S	18_K	0.900	1.00
188_D	192_E	0.892	1.00
36_E	40_R	0.888	1.00
150_V	154_W	0.886	1.00
159_E	163_I	0.884	1.00
209_I	242_V	0.883	1.00
239_Q	243_A	0.882	1.00
182_A	186_V	0.876	1.00
28_E	40_R	0.875	1.00
199_N	230_T	0.875	1.00
185_P	189_Q	0.874	1.00
160_V	187_L	0.871	1.00
152_L	183_L	0.870	1.00
172_S	176_T	0.865	1.00
150_V	220_V	0.865	1.00
184_L	188_D	0.863	1.00
172_S	202_Q	0.863	1.00
56_K	70_Y	0.861	1.00
185_P	188_D	0.860	1.00
22_I	41_V	0.859	1.00
162_Q	166_G	0.855	1.00
200_E	204_E	0.851	1.00
46_S	49_Y	0.851	1.00
90_I	94_D	0.851	1.00
97_M	122_H	0.849	1.00
215_D	221_I	0.846	1.00
238_L	242_V	0.845	1.00
97_M	224_L	0.844	1.00
109_H	227_S	0.843	1.00
238_L	243_A	0.841	1.00
26_L	29_E	0.840	1.00
193_Q	242_V	0.834	1.00
26_L	30_R	0.833	1.00
147_I	225_S	0.825	1.00
182_A	185_P	0.823	1.00
210_A	225_S	0.816	1.00
150_V	190_V	0.815	1.00
18_K	47_T	0.812	1.00
22_I	51_F	0.810	1.00
245_L	249_A	0.796	1.00
96_Q	252_I	0.794	1.00
12_S	17_L	0.792	1.00
153_A	187_L	0.792	1.00
106_E	128_Y	0.787	1.00
146_A	210_A	0.785	1.00
248_A	251_K	0.785	1.00
113_L	159_E	0.783	1.00
177_I	182_A	0.782	1.00
114_D	119_V	0.780	1.00
63_Q	67_S	0.773	1.00
240_E	243_A	0.772	1.00
43_M	47_T	0.768	1.00
34_I	52_L	0.766	1.00
189_Q	192_E	0.757	1.00
186_V	190_V	0.757	1.00
62_A	73_T	0.748	1.00
53_Q	56_K	0.746	1.00
15_S	19_V	0.746	1.00
128_Y	232_R	0.744	1.00
186_V	193_Q	0.743	1.00
151_L	223_G	0.739	1.00
229_P	232_R	0.735	1.00
209_I	238_L	0.733	1.00
197_E	238_L	0.731	1.00
23_L	60_Y	0.730	1.00
32_I	37_L	0.730	1.00
76_L	80_G	0.728	1.00
76_L	79_L	0.727	1.00
41_V	48_V	0.727	1.00
34_I	48_V	0.723	1.00
208_C	227_S	0.722	1.00
89_L	93_A	0.722	1.00
243_A	246_H	0.722	1.00
163_I	167_V	0.719	1.00
208_C	225_S	0.717	1.00
160_V	163_I	0.717	1.00
109_H	123_K	0.714	1.00
97_M	124_I	0.713	1.00
112_A	121_I	0.708	1.00
144_S	202_Q	0.708	1.00
149_K	190_V	0.699	1.00
214_F	221_I	0.698	1.00
199_N	235_E	0.694	1.00
53_Q	57_T	0.693	1.00
72_L	76_L	0.688	1.00
250_R	253_S	0.682	1.00
116_D	163_I	0.681	1.00
38_S	41_V	0.679	1.00
34_I	45_K	0.678	1.00
99_E	102_R	0.675	1.00
22_I	48_V	0.672	1.00
109_H	134_S	0.669	1.00
247_T	250_R	0.667	1.00
113_L	151_L	0.665	1.00
177_I	183_L	0.658	1.00
100_L	226_I	0.652	1.00
188_D	191_R	0.651	1.00
16_V	51_F	0.651	1.00
251_K	254_A	0.651	1.00
246_H	249_A	0.650	1.00
101_S	126_S	0.650	1.00
34_I	70_Y	0.649	1.00
88_D	91_R	0.648	1.00
62_A	74_L	0.646	1.00
211_V	253_S	0.646	1.00
92_S	95_I	0.646	1.00
152_L	187_L	0.645	1.00
237_R	241_Y	0.645	1.00
100_L	108_I	0.643	1.00
194_G	214_F	0.641	1.00
160_V	188_D	0.641	1.00
224_L	249_A	0.639	1.00
248_A	252_I	0.639	1.00
155_R	160_V	0.639	1.00
157_R	191_R	0.637	1.00
152_L	160_V	0.635	1.00
100_L	104_T	0.634	1.00
80_G	83_A	0.633	1.00
151_L	155_R	0.631	1.00
160_V	164_L	0.624	1.00
178_T	182_A	0.622	1.00
16_V	20_F	0.616	1.00
143_Y	169_Y	0.614	1.00
109_H	208_C	0.611	1.00
200_E	207_R	0.611	1.00
95_I	255_Q	0.608	1.00
224_L	248_A	0.608	1.00
173_T	177_I	0.607	1.00
21_G	24_Q	0.607	1.00
15_S	51_F	0.603	1.00
141_P	144_S	0.603	1.00
53_Q	63_Q	0.603	1.00
240_E	244_M	0.602	1.00
164_L	168_E	0.601	1.00
18_K	43_M	0.601	1.00
102_R	127_M	0.601	1.00
63_Q	68_E	0.600	1.00
105_K	127_M	0.599	1.00
63_Q	70_Y	0.598	1.00
120_Y	134_S	0.597	1.00
36_E	69_K	0.596	1.00
199_N	238_L	0.595	1.00
24_Q	78_E	0.594	1.00
175_R	204_E	0.594	1.00
135_R	138_R	0.594	1.00
21_G	25_A	0.590	1.00
108_I	124_I	0.589	1.00
106_E	228_F	0.586	1.00
150_V	210_A	0.583	1.00
150_V	212_P	0.576	1.00
98_R	122_H	0.574	1.00
27_G	79_L	0.574	1.00
16_V	54_T	0.573	1.00
64_E	69_K	0.572	1.00
13_V	51_F	0.571	1.00
211_V	224_L	0.571	1.00
244_M	248_A	0.571	1.00
19_V	51_F	0.569	1.00
23_L	79_L	0.569	1.00
125_D	135_R	0.567	1.00
145_T	208_C	0.562	1.00
106_E	226_I	0.561	1.00
27_G	72_L	0.561	1.00
38_S	45_K	0.557	0.99
241_Y	244_M	0.554	0.99
59_G	75_K	0.553	0.99
118_I	140_N	0.553	0.99
60_Y	75_K	0.552	0.99
25_A	29_E	0.551	0.99
213_V	253_S	0.551	0.99
169_Y	180_T	0.549	0.99
181_E	184_L	0.548	0.99
81_A	84_L	0.548	0.99
123_K	136_I	0.541	0.99
181_E	185_P	0.540	0.99
120_Y	147_I	0.540	0.99
118_I	147_I	0.540	0.99
151_L	222_A	0.537	0.99
154_W	191_R	0.536	0.99
123_K	134_S	0.536	0.99
195_Y	246_H	0.536	0.99
134_S	138_R	0.535	0.99
213_V	222_A	0.533	0.99
25_A	28_E	0.533	0.99
171_R	174_E	0.531	0.99
77_F	84_L	0.526	0.99
93_A	97_M	0.524	0.99
95_I	99_E	0.523	0.99
18_K	51_F	0.522	0.99
224_L	245_L	0.518	0.99
149_K	198_D	0.517	0.99
183_L	187_L	0.516	0.99
24_Q	79_L	0.515	0.99
33_G	45_K	0.514	0.99
150_V	196_G	0.513	0.99
205_G	230_T	0.513	0.99
14_S	54_T	0.511	0.99
109_H	225_S	0.511	0.99
92_S	252_I	0.509	0.99
19_V	55_M	0.509	0.99
120_Y	145_T	0.508	0.99
130_L	231_L	0.508	0.99
107_T	123_K	0.507	0.99
186_V	196_G	0.507	0.99
118_I	145_T	0.506	0.99
78_E	82_R	0.501	0.99
122_H	136_I	0.501	0.99
236_E	240_E	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mq0A	2	0.9506	100	0.108	Contact Map
2ia2A	4	0.943	100	0.119	Contact Map
2g7uA	6	0.9506	100	0.121	Contact Map
3r4kA	2	0.9544	100	0.128	Contact Map
1mkmA	4	0.9354	100	0.129	Contact Map
2xrnA	3	0.9125	100	0.147	Contact Map
2o0yA	4	0.962	100	0.164	Contact Map
1yspA	1	0.6236	100	0.421	Contact Map
1tf1A	1	0.6996	100	0.425	Contact Map
1ysqA	1	0.6616	100	0.429	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0087 seconds.