YOAA - ECOLI - GREMLIN Contacts

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YOAA - Probable ATP-dependent helicase YoaA

UniProt:	P76257	Sequences: MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVEAGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKGRSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPLVTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPEADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLAQSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDAAFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSWIFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVLRNLPQTNQPGSARQLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFDEVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIARAVRFLAIPSSR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13513
Length:	636 (589)
Sequences:	4187 (3100)
Seq/√Len:	127.7

ECOLI - YOAA DING
BACSU - DING YPVA
HALSA - Q9HMP9 Q9HQ08 Q9HMM1
SULSO - Q980I2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
427_D	430_R	6.338	1.00
450_R	483_Q	4.572	1.00
59_A	223_I	4.546	1.00
456_L	536_I	4.360	1.00
471_C	480_L	4.318	1.00
227_A	394_F	4.308	1.00
201_F	224_F	4.077	1.00
15_I	18_F	4.072	1.00
460_I	467_C	3.914	1.00
484_F	516_V	3.826	1.00
108_C	179_C	3.613	1.00
471_C	516_V	3.519	1.00
27_M	43_V	3.465	1.00
35_I	221_V	3.335	1.00
22_E	26_Q	3.253	1.00
463_N	467_C	3.171	1.00
557_C	562_G	2.989	1.00
459_I	595_V	2.903	1.00
466_R	533_S	2.886	1.00
584_L	592_G	2.827	1.00
34_A	41_L	2.791	1.00
456_L	469_M	2.690	1.00
481_A	494_L	2.629	1.00
19_K	588_A	2.629	1.00
596_I	601_L	2.611	1.00
84_L	97_V	2.601	1.00
437_L	440_L	2.537	1.00
98_A	191_A	2.522	1.00
409_T	419_S	2.520	1.00
30_A	420_L	2.480	1.00
27_M	395_T	2.479	1.00
59_A	66_V	2.468	1.00
522_W	580_G	2.466	1.00
474_H	518_T	2.455	1.00
39_Q	418_E	2.363	1.00
493_L	513_A	2.353	1.00
52_T	79_L	2.330	1.00
276_A	280_Q	2.316	1.00
459_I	534_L	2.274	1.00
577_L	596_I	2.216	1.00
23_P	422_L	2.211	1.00
453_A	483_Q	2.207	1.00
475_A	479_D	2.183	1.00
145_I	158_W	2.179	1.00
455_M	597_C	2.166	1.00
505_Q	509_S	2.166	1.00
454_A	487_T	2.122	1.00
581_V	594_L	2.113	1.00
224_F	230_L	2.103	1.00
467_C	534_L	2.067	1.00
33_Q	37_K	2.060	1.00
136_W	140_T	2.040	1.00
457_R	487_T	2.038	1.00
528_R	587_D	2.037	1.00
465_G	530_D	2.032	1.00
534_L	595_V	2.022	1.00
401_V	404_D	2.018	1.00
142_D	147_T	2.011	1.00
229_Q	523_E	2.005	1.00
574_V	610_F	1.988	1.00
75_L	78_Q	1.922	1.00
460_I	514_L	1.913	1.00
241_S	371_A	1.862	1.00
510_A	513_A	1.854	1.00
530_D	533_S	1.839	1.00
42_V	408_F	1.838	1.00
466_R	490_L	1.837	1.00
25_R	29_V	1.824	1.00
73_K	76_Q	1.812	1.00
459_I	536_I	1.804	1.00
400_S	421_L	1.801	1.00
558_R	564_P	1.799	1.00
577_L	610_F	1.788	1.00
69_S	198_H	1.777	1.00
562_G	567_E	1.774	1.00
168_C	173_C	1.766	1.00
310_L	313_D	1.763	1.00
408_F	412_L	1.763	1.00
273_D	276_A	1.747	1.00
381_F	386_A	1.740	1.00
556_D	560_R	1.728	1.00
34_A	39_Q	1.723	1.00
30_A	418_E	1.717	1.00
42_V	409_T	1.702	1.00
555_E	558_R	1.702	1.00
55_Y	395_T	1.696	1.00
491_P	506_Q	1.681	1.00
453_A	480_L	1.674	1.00
389_P	392_W	1.668	1.00
471_C	477_M	1.663	1.00
463_N	534_L	1.656	1.00
581_V	596_I	1.639	1.00
54_A	58_P	1.633	1.00
35_I	393_I	1.630	1.00
336_F	339_A	1.624	1.00
477_M	494_L	1.614	1.00
502_Q	505_Q	1.609	1.00
356_G	360_W	1.593	1.00
339_A	345_R	1.588	1.00
83_D	88_S	1.576	1.00
66_V	223_I	1.572	1.00
533_S	591_R	1.570	1.00
536_I	597_C	1.570	1.00
335_A	338_R	1.569	1.00
83_D	86_T	1.566	1.00
503_L	515_L	1.562	1.00
100_L	194_V	1.562	1.00
535_V	584_L	1.559	1.00
34_A	391_S	1.549	1.00
241_S	369_T	1.548	1.00
537_I	594_L	1.546	1.00
31_V	58_P	1.539	1.00
566_D	605_P	1.539	1.00
501_G	505_Q	1.538	1.00
474_H	477_M	1.536	1.00
519_S	576_T	1.532	1.00
67_I	222_M	1.530	1.00
76_Q	80_Y	1.529	1.00
70_T	76_Q	1.527	1.00
555_E	559_L	1.526	1.00
279_A	286_L	1.519	1.00
100_L	188_A	1.512	1.00
485_R	497_E	1.509	1.00
477_M	516_V	1.504	1.00
554_M	569_Q	1.488	1.00
540_L	573_A	1.488	1.00
273_D	277_Q	1.485	1.00
27_M	31_V	1.484	1.00
295_L	298_L	1.482	1.00
186_K	189_M	1.467	1.00
222_M	392_W	1.466	1.00
386_A	394_F	1.465	1.00
491_P	511_G	1.451	1.00
109_L	180_F	1.431	1.00
99_L	195_V	1.430	1.00
340_T	345_R	1.427	1.00
38_G	390_G	1.423	1.00
275_L	282_F	1.417	1.00
338_R	345_R	1.404	1.00
336_F	340_T	1.404	1.00
271_C	275_L	1.402	1.00
275_L	279_A	1.401	1.00
31_V	393_I	1.398	1.00
231_P	411_R	1.397	1.00
42_V	412_L	1.391	1.00
491_P	510_A	1.386	1.00
268_L	274_R	1.384	1.00
337_E	341_L	1.382	1.00
319_Y	322_A	1.368	1.00
127_L	133_L	1.362	1.00
508_V	531_T	1.361	1.00
343_R	347_K	1.359	1.00
557_C	568_V	1.346	1.00
222_M	389_P	1.343	1.00
110_E	113_E	1.341	1.00
72_S	78_Q	1.341	1.00
511_G	530_D	1.339	1.00
527_V	531_T	1.339	1.00
611_L	619_R	1.336	1.00
279_A	282_F	1.335	1.00
542_F	606_Y	1.331	1.00
108_C	173_C	1.331	1.00
464_N	490_L	1.331	1.00
294_N	298_L	1.329	1.00
68_I	79_L	1.327	1.00
274_R	278_S	1.322	1.00
371_A	549_L	1.322	1.00
537_I	581_V	1.321	1.00
72_S	83_D	1.310	1.00
566_D	570_L	1.306	1.00
64_K	220_D	1.306	1.00
464_N	512_N	1.304	1.00
394_F	408_F	1.304	1.00
493_L	510_A	1.302	1.00
79_L	83_D	1.298	1.00
318_C	322_A	1.296	1.00
72_S	75_L	1.292	1.00
67_I	219_A	1.291	1.00
41_L	393_I	1.289	1.00
469_M	514_L	1.287	1.00
73_K	105_N	1.285	1.00
449_A	453_A	1.281	1.00
73_K	78_Q	1.277	1.00
405_L	419_S	1.270	1.00
450_R	454_A	1.264	1.00
112_L	137_S	1.261	1.00
101_K	144_D	1.261	1.00
213_G	216_I	1.260	1.00
342_Y	345_R	1.254	1.00
474_H	478_R	1.250	1.00
353_N	357_Y	1.250	1.00
95_G	193_V	1.249	1.00
275_L	278_S	1.248	1.00
173_C	179_C	1.245	1.00
478_R	497_E	1.240	1.00
356_G	359_Y	1.233	1.00
542_F	570_L	1.227	1.00
84_L	88_S	1.221	0.99
271_C	286_L	1.221	0.99
272_A	278_S	1.216	0.99
472_T	539_K	1.214	0.99
353_N	356_G	1.212	0.99
313_D	320_D	1.209	0.99
110_E	114_Q	1.208	0.99
506_Q	509_S	1.206	0.99
96_N	192_D	1.205	0.99
458_P	461_E	1.204	0.99
221_V	391_S	1.203	0.99
26_Q	29_V	1.201	0.99
279_A	285_Q	1.199	0.99
127_L	130_V	1.199	0.99
268_L	271_C	1.191	0.99
437_L	441_P	1.191	0.99
133_L	136_W	1.189	0.99
232_D	572_D	1.189	0.99
274_R	277_Q	1.183	0.99
478_R	482_E	1.181	0.99
382_K	386_A	1.181	0.99
296_R	299_L	1.178	0.99
75_L	80_Y	1.177	0.99
470_L	522_W	1.172	0.99
382_K	415_E	1.169	0.99
278_S	281_D	1.168	0.99
481_A	485_R	1.167	0.99
42_V	399_L	1.163	0.99
554_M	558_R	1.156	0.99
30_A	41_L	1.153	0.99
340_T	344_T	1.151	0.99
201_F	222_M	1.150	0.99
235_S	553_R	1.149	0.99
60_L	95_G	1.147	0.99
80_Y	195_V	1.143	0.99
84_L	195_V	1.142	0.99
338_R	346_L	1.133	0.99
21_R	24_Q	1.132	0.99
441_P	451_Q	1.128	0.99
500_K	521_F	1.127	0.99
582_G	586_R	1.122	0.99
454_A	458_P	1.115	0.99
494_L	497_E	1.113	0.99
563_D	566_D	1.113	0.99
353_N	358_S	1.111	0.99
357_Y	360_W	1.109	0.99
276_A	286_L	1.108	0.99
608_A	612_A	1.106	0.99
479_D	482_E	1.105	0.99
267_Q	270_K	1.105	0.99
483_Q	487_T	1.103	0.99
604_R	607_G	1.103	0.99
532_L	584_L	1.102	0.99
449_A	480_L	1.100	0.99
52_T	224_F	1.097	0.99
500_K	520_S	1.093	0.99
453_A	484_F	1.091	0.99
244_S	368_F	1.091	0.99
490_L	512_N	1.089	0.99
75_L	79_L	1.087	0.99
280_Q	283_R	1.087	0.99
76_Q	197_N	1.085	0.99
202_L	234_A	1.083	0.99
280_Q	284_L	1.082	0.99
40_P	391_S	1.082	0.99
337_E	340_T	1.079	0.99
305_Q	308_F	1.078	0.99
502_Q	506_Q	1.074	0.99
492_V	516_V	1.074	0.99
583_R	586_R	1.073	0.99
302_P	305_Q	1.069	0.99
490_L	495_Q	1.068	0.99
202_L	230_L	1.064	0.99
46_G	425_P	1.058	0.99
110_E	169_L	1.058	0.99
46_G	422_L	1.055	0.98
21_R	45_A	1.053	0.98
73_K	77_D	1.052	0.98
439_N	455_M	1.051	0.98
281_D	284_L	1.051	0.98
410_S	562_G	1.049	0.98
344_T	347_K	1.046	0.98
494_L	498_T	1.042	0.98
70_T	197_N	1.042	0.98
147_T	151_V	1.039	0.98
320_D	323_K	1.039	0.98
339_A	342_Y	1.035	0.98
425_P	529_G	1.035	0.98
332_L	345_R	1.032	0.98
353_N	359_Y	1.031	0.98
298_L	302_P	1.026	0.98
354_Q	357_Y	1.023	0.98
536_I	595_V	1.019	0.98
277_Q	281_D	1.019	0.98
71_G	233_I	1.017	0.98
224_F	394_F	1.014	0.98
356_G	361_Y	1.013	0.98
316_E	319_Y	1.010	0.98
532_L	592_G	1.009	0.98
30_A	33_Q	1.004	0.98
294_N	297_E	0.995	0.98
452_L	456_L	0.993	0.98
44_E	421_L	0.992	0.98
272_A	275_L	0.992	0.98
438_R	441_P	0.990	0.98
493_L	506_Q	0.989	0.98
335_A	342_Y	0.985	0.98
315_L	326_L	0.982	0.98
313_D	316_E	0.982	0.98
306_R	309_L	0.981	0.98
438_R	442_Q	0.978	0.98
80_Y	99_L	0.978	0.98
276_A	283_R	0.973	0.97
285_Q	288_E	0.973	0.97
550_L	568_V	0.972	0.97
478_R	494_L	0.972	0.97
468_F	517_A	0.972	0.97
466_R	511_G	0.967	0.97
35_I	391_S	0.967	0.97
113_E	175_M	0.964	0.97
338_R	341_L	0.962	0.97
148_C	152_A	0.960	0.97
266_Q	271_C	0.960	0.97
552_A	555_E	0.959	0.97
293_G	296_R	0.954	0.97
534_L	593_V	0.953	0.97
439_N	442_Q	0.950	0.97
448_S	452_L	0.947	0.97
286_L	289_P	0.943	0.97
196_V	201_F	0.941	0.97
46_G	424_S	0.939	0.97
337_E	346_L	0.935	0.97
23_P	423_P	0.934	0.97
76_Q	79_L	0.933	0.97
550_L	569_Q	0.931	0.97
40_P	43_V	0.931	0.97
32_T	36_E	0.930	0.97
314_T	318_C	0.928	0.97
80_Y	97_V	0.928	0.97
72_S	76_Q	0.924	0.97
69_S	201_F	0.921	0.96
340_T	348_R	0.915	0.96
48_G	51_K	0.914	0.96
244_S	248_L	0.913	0.96
55_Y	68_I	0.913	0.96
56_L	79_L	0.912	0.96
468_F	535_V	0.910	0.96
341_L	345_R	0.909	0.96
335_A	347_K	0.907	0.96
274_R	279_A	0.905	0.96
335_A	345_R	0.905	0.96
337_E	347_K	0.904	0.96
246_Q	341_L	0.904	0.96
270_K	274_R	0.901	0.96
275_L	283_R	0.900	0.96
342_Y	347_K	0.898	0.96
87_V	92_K	0.896	0.96
102_G	197_N	0.895	0.96
579_Q	582_G	0.894	0.96
604_R	608_A	0.894	0.96
357_Y	361_Y	0.893	0.96
481_A	492_V	0.892	0.96
269_Q	273_D	0.889	0.96
457_R	461_E	0.889	0.96
461_E	489_T	0.888	0.96
545_P	565_F	0.887	0.96
52_T	56_L	0.886	0.96
475_A	478_R	0.884	0.96
412_L	417_A	0.884	0.96
355_P	358_S	0.883	0.95
136_W	143_G	0.881	0.95
107_L	170_G	0.875	0.95
442_Q	599_N	0.875	0.95
308_F	312_D	0.875	0.95
293_G	298_L	0.868	0.95
396_S	526_D	0.865	0.95
311_L	314_T	0.864	0.95
468_F	580_G	0.864	0.95
431_Q	585_I	0.857	0.95
268_L	272_A	0.855	0.95
575_I	578_K	0.854	0.95
483_Q	486_A	0.854	0.95
60_L	193_V	0.852	0.95
543_T	572_D	0.852	0.95
273_D	284_L	0.851	0.94
476_M	538_D	0.849	0.94
489_T	495_Q	0.848	0.94
405_L	408_F	0.846	0.94
446_P	479_D	0.845	0.94
243_S	369_T	0.844	0.94
77_D	501_G	0.843	0.94
100_L	184_A	0.842	0.94
452_L	597_C	0.842	0.94
518_T	522_W	0.840	0.94
340_T	346_L	0.839	0.94
103_R	108_C	0.839	0.94
466_R	534_L	0.835	0.94
71_G	229_Q	0.834	0.94
97_V	193_V	0.833	0.94
537_I	577_L	0.833	0.94
451_Q	454_A	0.831	0.94
355_P	359_Y	0.830	0.94
480_L	483_Q	0.827	0.94
142_D	145_I	0.825	0.94
311_L	322_A	0.825	0.94
47_T	375_L	0.824	0.93
231_P	408_F	0.823	0.93
307_A	310_L	0.823	0.93
290_G	298_L	0.823	0.93
522_W	578_K	0.821	0.93
400_S	405_L	0.819	0.93
28_A	58_P	0.819	0.93
165_N	168_C	0.815	0.93
307_A	311_L	0.814	0.93
18_F	25_R	0.814	0.93
276_A	284_L	0.814	0.93
163_S	167_N	0.814	0.93
284_L	288_E	0.810	0.93
304_I	307_A	0.810	0.93
35_I	59_A	0.809	0.93
434_L	596_I	0.808	0.93
121_D	130_V	0.807	0.93
267_Q	274_R	0.806	0.93
272_A	279_A	0.806	0.93
452_L	538_D	0.805	0.93
84_L	193_V	0.805	0.93
100_L	196_V	0.804	0.93
34_A	40_P	0.803	0.93
196_V	200_L	0.802	0.93
411_R	553_R	0.802	0.93
78_Q	83_D	0.800	0.92
465_G	533_S	0.799	0.92
314_T	319_Y	0.799	0.92
336_F	347_K	0.798	0.92
212_F	215_L	0.796	0.92
440_L	448_S	0.795	0.92
228_H	396_S	0.795	0.92
345_R	349_L	0.794	0.92
356_G	362_E	0.791	0.92
85_P	88_S	0.790	0.92
459_I	597_C	0.790	0.92
235_S	239_G	0.790	0.92
554_M	566_D	0.785	0.92
515_L	518_T	0.785	0.92
546_D	551_K	0.783	0.92
116_A	121_D	0.782	0.92
601_L	611_L	0.782	0.92
397_A	426_F	0.780	0.91
319_Y	323_K	0.779	0.91
238_F	380_K	0.779	0.91
284_L	287_G	0.774	0.91
77_D	80_Y	0.773	0.91
432_A	581_V	0.773	0.91
579_Q	583_R	0.773	0.91
266_Q	270_K	0.773	0.91
73_K	80_Y	0.770	0.91
157_A	161_V	0.769	0.91
469_M	516_V	0.769	0.91
279_A	283_R	0.766	0.91
267_Q	271_C	0.764	0.91
504_L	527_V	0.764	0.91
479_D	483_Q	0.763	0.91
496_G	499_S	0.761	0.90
279_A	284_L	0.761	0.90
234_A	374_P	0.761	0.90
482_E	486_A	0.761	0.90
480_L	516_V	0.760	0.90
178_D	183_K	0.760	0.90
458_P	462_A	0.760	0.90
23_P	49_T	0.760	0.90
565_F	569_Q	0.759	0.90
579_Q	586_R	0.759	0.90
29_V	33_Q	0.758	0.90
103_R	204_D	0.758	0.90
432_A	617_A	0.756	0.90
457_R	484_F	0.756	0.90
594_L	617_A	0.755	0.90
283_R	287_G	0.755	0.90
558_R	563_D	0.755	0.90
248_L	276_A	0.753	0.90
596_I	614_L	0.752	0.90
574_V	577_L	0.752	0.90
243_S	246_Q	0.751	0.90
542_F	565_F	0.750	0.90
444_N	449_A	0.749	0.90
71_G	75_L	0.749	0.90
302_P	306_R	0.749	0.90
336_F	342_Y	0.746	0.90
282_F	286_L	0.745	0.90
336_F	349_L	0.743	0.89
269_Q	276_A	0.741	0.89
49_T	405_L	0.741	0.89
302_P	307_A	0.740	0.89
43_V	422_L	0.735	0.89
116_A	134_R	0.735	0.89
274_R	286_L	0.735	0.89
28_A	32_T	0.735	0.89
303_Q	307_A	0.734	0.89
353_N	361_Y	0.728	0.88
316_E	320_D	0.728	0.88
278_S	282_F	0.727	0.88
467_C	504_L	0.726	0.88
279_A	287_G	0.726	0.88
297_E	300_A	0.723	0.88
20_P	25_R	0.723	0.88
574_V	613_S	0.721	0.88
495_Q	565_F	0.721	0.88
310_L	314_T	0.720	0.88
199_H	237_Y	0.720	0.88
305_Q	309_L	0.719	0.88
43_V	420_L	0.719	0.88
45_A	49_T	0.718	0.88
82_R	86_T	0.716	0.88
55_Y	198_H	0.716	0.88
529_G	587_D	0.714	0.87
140_T	144_D	0.714	0.87
494_L	516_V	0.713	0.87
98_A	184_A	0.712	0.87
607_G	615_P	0.712	0.87
68_I	198_H	0.711	0.87
96_N	187_K	0.711	0.87
570_L	605_P	0.707	0.87
17_G	21_R	0.706	0.87
440_L	451_Q	0.706	0.87
551_K	555_E	0.705	0.87
433_L	593_V	0.705	0.87
469_M	536_I	0.704	0.87
269_Q	279_A	0.704	0.87
507_F	532_L	0.703	0.87
56_L	580_G	0.702	0.87
440_L	443_T	0.702	0.87
317_L	322_A	0.701	0.86
61_R	64_K	0.699	0.86
435_C	595_V	0.699	0.86
463_N	533_S	0.698	0.86
103_R	110_E	0.696	0.86
135_S	223_I	0.695	0.86
574_V	609_T	0.693	0.86
481_A	516_V	0.693	0.86
207_V	212_F	0.693	0.86
280_Q	286_L	0.693	0.86
102_G	426_F	0.693	0.86
339_A	346_L	0.692	0.86
468_F	527_V	0.692	0.86
143_G	147_T	0.691	0.86
484_F	488_M	0.690	0.86
276_A	279_A	0.689	0.86
575_I	585_I	0.688	0.85
44_E	49_T	0.688	0.85
442_Q	445_Q	0.688	0.85
101_K	197_N	0.688	0.85
308_F	314_T	0.688	0.85
311_L	328_R	0.687	0.85
200_L	203_A	0.687	0.85
472_T	522_W	0.685	0.85
327_G	333_D	0.685	0.85
53_Y	57_A	0.684	0.85
491_P	494_L	0.683	0.85
136_W	147_T	0.680	0.85
133_L	141_V	0.680	0.85
335_A	339_A	0.679	0.85
331_L	349_L	0.679	0.85
315_L	318_C	0.678	0.85
273_D	280_Q	0.676	0.84
72_S	103_R	0.676	0.84
336_F	346_L	0.675	0.84
75_L	197_N	0.673	0.84
307_A	315_L	0.672	0.84
199_H	233_I	0.672	0.84
102_G	105_N	0.672	0.84
270_K	282_F	0.672	0.84
170_G	174_P	0.671	0.84
198_H	204_D	0.670	0.84
507_F	515_L	0.669	0.84
340_T	343_R	0.669	0.84
568_V	572_D	0.669	0.84
449_A	452_L	0.669	0.84
501_G	504_L	0.668	0.84
396_S	468_F	0.668	0.84
346_L	351_E	0.668	0.84
427_D	431_Q	0.667	0.84
65_K	191_A	0.665	0.83
308_F	321_V	0.664	0.83
303_Q	306_R	0.662	0.83
431_Q	434_L	0.662	0.83
378_A	413_G	0.662	0.83
342_Y	346_L	0.660	0.83
326_L	329_S	0.660	0.83
290_G	293_G	0.660	0.83
554_M	568_V	0.660	0.83
317_L	555_E	0.659	0.83
103_R	182_V	0.659	0.83
268_L	285_Q	0.658	0.83
79_L	195_V	0.658	0.83
585_I	590_D	0.658	0.83
382_K	385_M	0.657	0.83
313_D	322_A	0.657	0.83
161_V	168_C	0.657	0.83
323_K	326_L	0.652	0.82
311_L	318_C	0.652	0.82
495_Q	520_S	0.650	0.82
65_K	220_D	0.650	0.82
396_S	399_L	0.649	0.82
445_Q	448_S	0.648	0.82
482_E	485_R	0.648	0.82
561_G	564_P	0.648	0.82
226_E	583_R	0.647	0.82
96_N	162_T	0.647	0.82
85_P	168_C	0.646	0.82
449_A	476_M	0.646	0.82
59_A	221_V	0.645	0.82
226_E	579_Q	0.644	0.82
200_L	204_D	0.644	0.82
373_T	549_L	0.643	0.81
111_R	114_Q	0.642	0.81
195_V	357_Y	0.641	0.81
271_C	276_A	0.640	0.81
235_S	373_T	0.638	0.81
27_M	422_L	0.638	0.81
136_W	142_D	0.638	0.81
100_L	200_L	0.637	0.81
123_P	131_I	0.637	0.81
107_L	112_L	0.637	0.81
127_L	131_I	0.636	0.81
251_A	272_A	0.636	0.81
550_L	554_M	0.635	0.81
335_A	341_L	0.635	0.81
273_D	279_A	0.634	0.81
422_L	528_R	0.633	0.80
565_F	570_L	0.633	0.80
315_L	325_S	0.632	0.80
491_P	513_A	0.631	0.80
231_P	235_S	0.630	0.80
101_K	105_N	0.630	0.80
437_L	599_N	0.630	0.80
47_T	573_A	0.630	0.80
268_L	286_L	0.627	0.80
138_N	596_I	0.627	0.80
268_L	275_L	0.626	0.80
140_T	143_G	0.625	0.80
323_K	327_G	0.625	0.80
571_P	609_T	0.622	0.79
341_L	344_T	0.621	0.79
211_G	214_E	0.619	0.79
143_G	146_S	0.619	0.79
52_T	523_E	0.618	0.79
322_A	327_G	0.617	0.79
294_N	302_P	0.617	0.79
222_M	230_L	0.616	0.79
525_V	585_I	0.616	0.79
71_G	74_A	0.614	0.78
75_L	83_D	0.613	0.78
286_L	290_G	0.613	0.78
72_S	541_P	0.612	0.78
74_A	520_S	0.612	0.78
330_A	334_A	0.612	0.78
355_P	360_W	0.611	0.78
310_L	315_L	0.611	0.78
426_F	431_Q	0.611	0.78
345_R	348_R	0.611	0.78
543_T	554_M	0.611	0.78
133_L	140_T	0.610	0.78
202_L	372_L	0.610	0.78
577_L	601_L	0.609	0.78
309_L	315_L	0.609	0.78
198_H	470_L	0.609	0.78
233_I	236_Q	0.607	0.78
294_N	299_L	0.606	0.77
218_E	387_Q	0.606	0.77
313_D	319_Y	0.606	0.77
529_G	532_L	0.605	0.77
180_F	539_K	0.605	0.77
75_L	101_K	0.605	0.77
363_C	368_F	0.604	0.77
110_E	179_C	0.604	0.77
32_T	223_I	0.603	0.77
295_L	299_L	0.603	0.77
37_K	418_E	0.603	0.77
221_V	393_I	0.603	0.77
273_D	286_L	0.602	0.77
283_R	286_L	0.602	0.77
109_L	113_E	0.601	0.77
398_T	586_R	0.601	0.77
298_L	303_Q	0.601	0.77
445_Q	449_A	0.600	0.77
232_D	236_Q	0.600	0.77
24_Q	48_G	0.598	0.77
299_L	307_A	0.598	0.77
30_A	422_L	0.596	0.76
66_V	193_V	0.596	0.76
407_H	500_K	0.595	0.76
60_L	249_D	0.595	0.76
581_V	617_A	0.595	0.76
272_A	286_L	0.594	0.76
526_D	592_G	0.594	0.76
375_L	553_R	0.593	0.76
226_E	586_R	0.593	0.76
45_A	197_N	0.592	0.76
27_M	54_A	0.592	0.76
21_R	584_L	0.592	0.76
31_V	395_T	0.591	0.76
73_K	79_L	0.591	0.76
56_L	60_L	0.591	0.76
355_P	362_E	0.588	0.75
74_A	78_Q	0.588	0.75
401_V	405_L	0.587	0.75
34_A	393_I	0.587	0.75
204_D	217_P	0.586	0.75
214_E	217_P	0.585	0.75
44_E	400_S	0.585	0.75
65_K	328_R	0.585	0.75
63_K	221_V	0.585	0.75
70_T	74_A	0.585	0.75
302_P	308_F	0.584	0.75
248_L	252_K	0.581	0.74
465_G	512_N	0.581	0.74
199_H	474_H	0.581	0.74
278_S	286_L	0.581	0.74
45_A	58_P	0.580	0.74
496_G	503_L	0.580	0.74
95_G	192_D	0.579	0.74
507_F	531_T	0.578	0.74
31_V	55_Y	0.578	0.74
573_A	610_F	0.578	0.74
266_Q	269_Q	0.575	0.74
108_C	590_D	0.575	0.74
283_R	363_C	0.574	0.74
103_R	181_V	0.571	0.73
75_L	520_S	0.571	0.73
459_I	593_V	0.570	0.73
131_I	182_V	0.570	0.73
586_R	590_D	0.570	0.73
449_A	483_Q	0.570	0.73
118_A	121_D	0.569	0.73
561_G	565_F	0.569	0.73
577_L	614_L	0.569	0.73
45_A	397_A	0.568	0.73
68_I	71_G	0.567	0.73
321_V	324_L	0.567	0.73
356_G	365_S	0.566	0.73
505_Q	508_V	0.566	0.73
227_A	474_H	0.565	0.72
82_R	87_V	0.565	0.72
55_Y	76_Q	0.563	0.72
270_K	273_D	0.563	0.72
226_E	524_G	0.561	0.72
33_Q	418_E	0.561	0.72
401_V	574_V	0.561	0.72
610_F	613_S	0.560	0.72
23_P	230_L	0.560	0.72
226_E	582_G	0.560	0.72
341_L	349_L	0.559	0.72
573_A	592_G	0.559	0.72
311_L	317_L	0.559	0.72
130_V	133_L	0.559	0.72
333_D	337_E	0.558	0.72
49_T	425_P	0.558	0.72
69_S	233_I	0.558	0.72
181_V	185_R	0.558	0.72
500_K	504_L	0.557	0.71
180_F	183_K	0.557	0.71
20_P	28_A	0.557	0.71
73_K	500_K	0.555	0.71
324_L	328_R	0.553	0.71
49_T	424_S	0.553	0.71
280_Q	288_E	0.552	0.71
437_L	442_Q	0.552	0.71
46_G	68_I	0.552	0.71
105_N	507_F	0.551	0.71
456_L	514_L	0.551	0.71
220_D	389_P	0.551	0.71
197_N	542_F	0.551	0.71
83_D	374_P	0.550	0.70
455_M	458_P	0.550	0.70
200_L	215_L	0.550	0.70
275_L	284_L	0.548	0.70
236_Q	239_G	0.548	0.70
21_R	28_A	0.547	0.70
175_M	178_D	0.546	0.70
354_Q	358_S	0.546	0.70
456_L	484_F	0.546	0.70
177_K	271_C	0.546	0.70
268_L	273_D	0.546	0.70
82_R	98_A	0.545	0.70
335_A	340_T	0.545	0.70
140_T	147_T	0.545	0.70
17_G	20_P	0.544	0.70
231_P	553_R	0.544	0.70
157_A	160_L	0.544	0.70
24_Q	50_G	0.543	0.69
226_E	398_T	0.542	0.69
46_G	55_Y	0.542	0.69
309_L	313_D	0.540	0.69
76_Q	83_D	0.538	0.69
484_F	492_V	0.538	0.69
36_E	66_V	0.538	0.69
381_F	412_L	0.537	0.69
529_G	533_S	0.536	0.68
338_R	343_R	0.536	0.68
300_A	303_Q	0.536	0.68
249_D	252_K	0.535	0.68
184_A	573_A	0.534	0.68
96_N	191_A	0.534	0.68
105_N	197_N	0.532	0.68
55_Y	470_L	0.532	0.68
527_V	533_S	0.532	0.68
66_V	75_L	0.531	0.68
314_T	328_R	0.530	0.68
312_D	318_C	0.530	0.68
519_S	523_E	0.529	0.67
393_I	464_N	0.529	0.67
429_S	616_P	0.529	0.67
73_K	197_N	0.528	0.67
490_L	514_L	0.528	0.67
501_G	530_D	0.527	0.67
335_A	343_R	0.526	0.67
271_C	278_S	0.526	0.67
78_Q	85_P	0.526	0.67
446_P	450_R	0.526	0.67
293_G	297_E	0.525	0.67
251_A	273_D	0.525	0.67
211_G	215_L	0.525	0.67
134_R	137_S	0.524	0.67
572_D	576_T	0.524	0.67
204_D	207_V	0.523	0.67
70_T	75_L	0.523	0.67
310_L	316_E	0.523	0.67
271_C	327_G	0.523	0.67
499_S	502_Q	0.522	0.66
55_Y	79_L	0.522	0.66
108_C	228_H	0.521	0.66
342_Y	349_L	0.520	0.66
183_K	478_R	0.519	0.66
37_K	40_P	0.518	0.66
179_C	539_K	0.518	0.66
335_A	344_T	0.518	0.66
540_L	548_P	0.517	0.66
382_K	387_Q	0.517	0.66
46_G	50_G	0.517	0.66
170_G	173_C	0.517	0.66
93_Y	190_D	0.517	0.66
35_I	390_G	0.517	0.66
434_L	437_L	0.516	0.66
21_R	27_M	0.516	0.66
504_L	521_F	0.516	0.66
274_R	280_Q	0.515	0.65
182_V	466_R	0.515	0.65
108_C	168_C	0.515	0.65
524_G	586_R	0.515	0.65
71_G	199_H	0.514	0.65
53_Y	539_K	0.514	0.65
317_L	320_D	0.512	0.65
268_L	278_S	0.512	0.65
49_T	181_V	0.511	0.65
274_R	282_F	0.511	0.65
161_V	172_D	0.510	0.65
466_R	513_A	0.510	0.65
98_A	188_A	0.510	0.65
300_A	304_I	0.509	0.65
362_E	371_A	0.509	0.65
335_A	346_L	0.508	0.64
233_I	474_H	0.507	0.64
524_G	579_Q	0.507	0.64
200_L	553_R	0.507	0.64
58_P	197_N	0.506	0.64
44_E	592_G	0.506	0.64
151_V	154_D	0.506	0.64
46_G	49_T	0.506	0.64
82_R	85_P	0.505	0.64
580_G	592_G	0.505	0.64
182_V	185_R	0.505	0.64
407_H	411_R	0.504	0.64
599_N	603_M	0.504	0.64
322_A	328_R	0.504	0.64
460_I	490_L	0.504	0.64
24_Q	51_K	0.504	0.64
342_Y	350_K	0.503	0.64
383_E	387_Q	0.502	0.63
212_F	216_I	0.502	0.63
341_L	347_K	0.501	0.63
231_P	407_H	0.501	0.63
306_R	313_D	0.501	0.63
158_W	161_V	0.501	0.63
338_R	347_K	0.501	0.63
303_Q	311_L	0.500	0.63
333_D	339_A	0.500	0.63
69_S	525_V	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4a15A	1	0.9104	100	0.328	Contact Map
3crvA	1	0.8428	100	0.371	Contact Map
2vl7A	1	0.7044	100	0.398	Contact Map
1gkuB	1	0.6101	100	0.745	Contact Map
4ys0A	1	0.827	100	0.771	Contact Map
4dduA	1	0.6415	100	0.776	Contact Map
3fhoA	2	0.467	100	0.782	Contact Map
3oiyA	1	0.6022	100	0.787	Contact Map
4a2qA	1	0.6887	100	0.791	Contact Map
2ykgA	1	0.7107	100	0.792	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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