YEAJ - ECOLI - GREMLIN Contacts

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YEAJ - Putative diguanylate cyclase YeaJ

UniProt:	P76237	Sequences: MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQKADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHKYPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDLNDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHFRLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDTLGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13496
Length:	496 (426)
Sequences:	2220 (2156)
Seq/√Len:	104.5

ECOLI - YEAJ YEDQ YEGE YDAM DOSC YLIF GMR DOSP YEAI YFIN YEAP YDEH YLIE YCDT
BACSU - YTRP YKOW

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
414_R	417_D	6.840	1.00
385_K	493_N	6.601	1.00
379_I	463_S	5.028	1.00
379_I	443_P	4.875	1.00
377_M	467_A	3.947	1.00
342_R	346_S	3.929	1.00
333_H	337_Y	3.848	1.00
358_L	428_C	3.440	1.00
444_E	447_E	3.284	1.00
365_R	368_K	3.235	1.00
383_M	461_F	3.042	1.00
352_L	406_A	3.030	1.00
482_D	486_Y	2.889	1.00
362_L	474_L	2.886	1.00
473_T	476_D	2.873	1.00
408_A	453_I	2.868	1.00
396_Q	479_K	2.856	1.00
395_H	486_Y	2.848	1.00
413_I	419_A	2.787	1.00
450_L	461_F	2.733	1.00
358_L	420_I	2.711	1.00
409_I	419_A	2.709	1.00
395_H	482_D	2.600	1.00
425_D	460_G	2.577	1.00
384_D	462_S	2.550	1.00
353_Y	418_Y	2.522	1.00
391_D	486_Y	2.516	1.00
391_D	395_H	2.481	1.00
451_Q	494_S	2.463	1.00
353_Y	357_I	2.433	1.00
431_L	442_L	2.421	1.00
424_G	486_Y	2.418	1.00
479_K	483_E	2.362	1.00
383_M	402_I	2.349	1.00
377_M	439_A	2.330	1.00
401_A	459_I	2.320	1.00
387_K	486_Y	2.229	1.00
371_Q	414_R	2.205	1.00
387_K	395_H	2.190	1.00
380_A	478_Y	2.185	1.00
443_P	465_I	2.125	1.00
389_I	401_A	2.096	1.00
386_L	402_I	2.079	1.00
391_D	482_D	2.059	1.00
471_N	480_A	2.043	1.00
439_A	443_P	2.023	1.00
417_D	445_R	2.018	1.00
383_M	405_L	2.003	1.00
488_N	492_K	2.002	1.00
387_K	391_D	1.974	1.00
334_F	337_Y	1.969	1.00
401_A	425_D	1.965	1.00
352_L	419_A	1.939	1.00
382_D	486_Y	1.913	1.00
422_L	478_Y	1.896	1.00
414_R	445_R	1.862	1.00
357_I	361_E	1.854	1.00
447_E	451_Q	1.852	1.00
387_K	482_D	1.849	1.00
379_I	429_I	1.841	1.00
469_K	480_A	1.825	1.00
380_A	485_L	1.804	1.00
337_Y	340_V	1.768	1.00
423_G	486_Y	1.760	1.00
404_L	407_Q	1.758	1.00
431_L	439_A	1.757	1.00
424_G	482_D	1.748	1.00
385_K	485_L	1.745	1.00
382_D	387_K	1.738	1.00
469_K	477_A	1.738	1.00
361_E	364_Q	1.738	1.00
468_M	471_N	1.728	1.00
406_A	419_A	1.727	1.00
395_H	426_E	1.705	1.00
464_G	481_S	1.704	1.00
384_D	492_K	1.703	1.00
333_H	336_L	1.693	1.00
435_T	438_I	1.675	1.00
361_E	418_Y	1.668	1.00
400_L	403_T	1.640	1.00
425_D	485_L	1.627	1.00
381_I	463_S	1.626	1.00
404_L	408_A	1.624	1.00
296_G	334_F	1.618	1.00
343_E	356_K	1.612	1.00
423_G	482_D	1.604	1.00
460_G	494_S	1.599	1.00
389_I	457_K	1.587	1.00
388_Q	425_D	1.582	1.00
386_L	488_N	1.576	1.00
468_M	477_A	1.562	1.00
420_I	428_C	1.558	1.00
391_D	424_G	1.520	1.00
466_Y	477_A	1.519	1.00
365_R	432_V	1.517	1.00
413_I	446_I	1.511	1.00
379_I	465_I	1.506	1.00
444_E	448_K	1.506	1.00
405_L	450_L	1.503	1.00
426_E	486_Y	1.494	1.00
383_M	460_G	1.494	1.00
395_H	424_G	1.482	1.00
361_E	420_I	1.477	1.00
380_A	428_C	1.443	1.00
357_I	360_P	1.443	1.00
350_T	402_I	1.427	1.00
308_F	311_S	1.421	1.00
409_I	446_I	1.416	1.00
349_M	402_I	1.410	1.00
462_S	492_K	1.408	1.00
348_A	356_K	1.401	1.00
385_K	425_D	1.395	1.00
384_D	488_N	1.391	1.00
447_E	494_S	1.388	1.00
422_L	428_C	1.387	1.00
425_D	447_E	1.381	1.00
382_D	424_G	1.378	1.00
382_D	395_H	1.369	1.00
422_L	425_D	1.366	1.00
380_A	422_L	1.357	0.99
390_N	398_G	1.356	0.99
376_V	468_M	1.354	0.99
401_A	485_L	1.348	0.99
386_L	492_K	1.333	0.99
382_D	489_K	1.332	0.99
382_D	482_D	1.328	0.99
357_I	418_Y	1.313	0.99
393_L	425_D	1.278	0.99
359_T	422_L	1.274	0.99
431_L	434_S	1.273	0.99
462_S	488_N	1.272	0.99
414_R	442_L	1.271	0.99
428_C	478_Y	1.265	0.99
406_A	409_I	1.263	0.99
358_L	478_Y	1.258	0.99
391_D	426_E	1.254	0.99
330_V	337_Y	1.249	0.99
225_P	234_G	1.247	0.99
345_I	353_Y	1.238	0.99
346_S	485_L	1.233	0.99
423_G	426_E	1.232	0.99
409_I	413_I	1.224	0.99
443_P	463_S	1.215	0.99
352_L	409_I	1.211	0.99
381_I	429_I	1.209	0.99
337_Y	341_S	1.206	0.99
345_I	357_I	1.205	0.99
425_D	488_N	1.197	0.99
398_G	424_G	1.191	0.99
374_S	433_D	1.191	0.99
386_L	485_L	1.188	0.99
339_N	343_E	1.187	0.99
382_D	421_R	1.171	0.99
379_I	431_L	1.167	0.98
365_R	371_Q	1.166	0.98
472_D	480_A	1.164	0.98
383_M	485_L	1.162	0.98
434_S	439_A	1.155	0.98
377_M	434_S	1.154	0.98
368_K	371_Q	1.153	0.98
239_D	244_N	1.135	0.98
380_A	425_D	1.134	0.98
413_I	417_D	1.129	0.98
386_L	484_R	1.109	0.98
466_Y	480_A	1.104	0.98
439_A	465_I	1.101	0.98
365_R	418_Y	1.099	0.98
382_D	423_G	1.097	0.98
225_P	233_K	1.096	0.98
161_N	164_Y	1.091	0.98
329_M	337_Y	1.077	0.97
384_D	485_L	1.072	0.97
395_H	423_G	1.069	0.97
338_Q	341_S	1.064	0.97
460_G	485_L	1.059	0.97
357_I	420_I	1.046	0.97
407_Q	410_K	1.043	0.97
425_D	486_Y	1.041	0.97
346_S	353_Y	1.040	0.97
341_S	345_I	1.040	0.97
387_K	426_E	1.039	0.97
487_V	490_Q	1.031	0.97
391_D	489_K	1.027	0.97
382_D	399_D	1.026	0.97
371_Q	416_S	1.024	0.96
401_A	420_I	1.013	0.96
381_I	461_F	1.011	0.96
408_A	447_E	1.005	0.96
377_M	443_P	1.004	0.96
426_E	482_D	1.001	0.96
422_L	430_I	0.999	0.96
358_L	430_I	0.998	0.96
171_V	174_E	0.996	0.96
380_A	481_S	0.991	0.96
369_L	376_V	0.990	0.96
382_D	391_D	0.984	0.96
457_K	485_L	0.976	0.95
355_R	399_D	0.972	0.95
356_K	425_D	0.959	0.95
346_S	380_A	0.952	0.95
334_F	338_Q	0.951	0.95
209_I	213_Q	0.948	0.95
337_Y	393_L	0.947	0.95
365_R	376_V	0.947	0.95
399_D	421_R	0.945	0.95
381_I	409_I	0.943	0.94
485_L	493_N	0.940	0.94
460_G	492_K	0.940	0.94
105_G	109_T	0.939	0.94
386_L	425_D	0.938	0.94
434_S	438_I	0.936	0.94
340_V	345_I	0.935	0.94
466_Y	469_K	0.935	0.94
57_N	65_M	0.935	0.94
385_K	388_Q	0.925	0.94
383_M	425_D	0.925	0.94
440_A	444_E	0.921	0.94
399_D	424_G	0.921	0.94
421_R	426_E	0.914	0.93
263_V	302_S	0.912	0.93
447_E	460_G	0.911	0.93
393_L	457_K	0.911	0.93
393_L	401_A	0.909	0.93
378_F	428_C	0.905	0.93
425_D	482_D	0.905	0.93
106_L	109_T	0.904	0.93
258_W	261_L	0.897	0.93
442_L	445_R	0.897	0.93
312_S	322_T	0.892	0.93
486_Y	489_K	0.891	0.93
436_P	439_A	0.890	0.93
400_L	404_L	0.879	0.92
413_I	442_L	0.876	0.92
436_P	467_A	0.872	0.92
422_L	485_L	0.871	0.92
323_A	330_V	0.867	0.92
353_Y	420_I	0.866	0.92
386_L	462_S	0.865	0.91
225_P	232_L	0.864	0.91
390_N	424_G	0.863	0.91
387_K	424_G	0.861	0.91
70_A	73_S	0.856	0.91
425_D	494_S	0.855	0.91
372_S	433_D	0.853	0.91
329_M	332_M	0.850	0.91
405_L	446_I	0.849	0.91
353_Y	361_E	0.845	0.91
470_E	480_A	0.844	0.90
358_L	362_L	0.841	0.90
390_N	399_D	0.839	0.90
235_I	239_D	0.839	0.90
239_D	243_N	0.837	0.90
388_Q	485_L	0.836	0.90
168_Y	173_V	0.835	0.90
348_A	359_T	0.828	0.90
107_R	118_D	0.828	0.90
345_I	356_K	0.827	0.90
386_L	460_G	0.826	0.89
343_E	346_S	0.826	0.89
162_D	167_F	0.826	0.89
356_K	493_N	0.825	0.89
380_A	401_A	0.824	0.89
432_V	439_A	0.822	0.89
68_L	71_E	0.821	0.89
263_V	267_D	0.819	0.89
384_D	482_D	0.819	0.89
336_L	339_N	0.817	0.89
448_K	451_Q	0.817	0.89
326_L	330_V	0.816	0.89
391_D	423_G	0.815	0.89
382_D	398_G	0.813	0.89
391_D	462_S	0.813	0.89
207_S	210_Y	0.810	0.89
382_D	426_E	0.810	0.89
273_D	278_Q	0.809	0.89
480_A	484_R	0.807	0.88
474_L	478_Y	0.804	0.88
237_L	244_N	0.802	0.88
70_A	74_E	0.802	0.88
371_Q	417_D	0.801	0.88
398_G	423_G	0.801	0.88
439_A	467_A	0.799	0.88
378_F	478_Y	0.799	0.88
476_D	480_A	0.798	0.88
199_V	202_G	0.793	0.88
420_I	474_L	0.792	0.87
169_E	174_E	0.791	0.87
344_N	423_G	0.789	0.87
293_L	296_G	0.788	0.87
366_L	477_A	0.787	0.87
484_R	488_N	0.787	0.87
386_L	443_P	0.787	0.87
346_S	352_L	0.784	0.87
490_Q	493_N	0.784	0.87
129_A	134_V	0.781	0.87
376_V	477_A	0.781	0.87
71_E	82_A	0.779	0.87
63_H	67_A	0.779	0.87
67_A	75_V	0.779	0.87
262_N	304_D	0.777	0.86
68_L	72_Q	0.777	0.86
58_Q	61_A	0.776	0.86
81_R	85_E	0.776	0.86
451_Q	460_G	0.776	0.86
362_L	430_I	0.775	0.86
366_L	468_M	0.773	0.86
254_R	329_M	0.773	0.86
61_A	67_A	0.771	0.86
348_A	389_I	0.768	0.86
67_A	71_E	0.767	0.86
378_F	466_Y	0.763	0.85
417_D	434_S	0.759	0.85
413_I	429_I	0.757	0.85
344_N	380_A	0.756	0.85
382_D	425_D	0.756	0.85
399_D	482_D	0.755	0.85
65_M	68_L	0.753	0.85
326_L	329_M	0.752	0.85
126_L	133_A	0.751	0.85
131_D	134_V	0.749	0.84
209_I	212_D	0.747	0.84
386_L	401_A	0.745	0.84
257_L	263_V	0.744	0.84
206_L	225_P	0.743	0.84
59_S	65_M	0.740	0.84
68_L	74_E	0.739	0.84
366_L	471_N	0.739	0.84
86_A	90_A	0.738	0.83
313_W	316_V	0.738	0.83
387_K	423_G	0.737	0.83
443_P	447_E	0.735	0.83
425_D	463_S	0.734	0.83
66_R	72_Q	0.732	0.83
326_L	331_R	0.732	0.83
100_A	103_Y	0.726	0.82
401_A	422_L	0.723	0.82
60_I	64_V	0.722	0.82
87_F	90_A	0.718	0.82
58_Q	65_M	0.718	0.82
267_D	302_S	0.717	0.82
417_D	442_L	0.717	0.82
378_F	477_A	0.717	0.82
405_L	459_I	0.716	0.82
487_V	491_N	0.715	0.82
319_W	329_M	0.713	0.81
443_P	461_F	0.713	0.81
406_A	410_K	0.711	0.81
466_Y	470_E	0.709	0.81
466_Y	481_S	0.708	0.81
210_Y	221_S	0.708	0.81
142_D	145_S	0.706	0.81
60_I	63_H	0.704	0.81
386_L	405_L	0.700	0.80
83_I	86_A	0.699	0.80
366_L	406_A	0.697	0.80
65_M	69_A	0.694	0.80
315_S	320_I	0.694	0.80
345_I	485_L	0.690	0.79
239_D	242_K	0.689	0.79
195_D	198_K	0.689	0.79
109_T	112_T	0.688	0.79
359_T	362_L	0.685	0.79
196_I	200_F	0.683	0.78
74_E	77_P	0.682	0.78
58_Q	64_V	0.681	0.78
352_L	401_A	0.680	0.78
457_K	483_E	0.680	0.78
421_R	424_G	0.678	0.78
462_S	486_Y	0.676	0.78
349_M	390_N	0.676	0.78
486_Y	493_N	0.676	0.78
387_K	489_K	0.676	0.78
60_I	67_A	0.675	0.78
170_P	174_E	0.674	0.78
395_H	399_D	0.673	0.77
356_K	486_Y	0.671	0.77
329_M	333_H	0.669	0.77
59_S	67_A	0.669	0.77
324_L	327_L	0.669	0.77
164_Y	168_Y	0.668	0.77
439_A	442_L	0.667	0.77
61_A	68_L	0.666	0.77
228_V	231_Q	0.666	0.77
360_P	418_Y	0.665	0.77
397_E	400_L	0.665	0.77
480_A	485_L	0.663	0.76
395_H	489_K	0.661	0.76
359_T	474_L	0.660	0.76
58_Q	66_R	0.660	0.76
403_T	407_Q	0.659	0.76
438_I	441_Q	0.659	0.76
330_V	333_H	0.658	0.76
363_E	367_Q	0.657	0.76
60_I	69_A	0.657	0.76
405_L	461_F	0.657	0.76
480_A	483_E	0.656	0.76
63_H	66_R	0.655	0.76
295_G	307_Y	0.654	0.75
69_A	74_E	0.653	0.75
64_V	67_A	0.653	0.75
360_P	364_Q	0.652	0.75
62_A	65_M	0.652	0.75
319_W	322_T	0.650	0.75
482_D	489_K	0.650	0.75
278_Q	281_D	0.649	0.75
254_R	287_V	0.649	0.75
422_L	461_F	0.649	0.75
62_A	67_A	0.647	0.75
382_D	462_S	0.645	0.74
264_T	267_D	0.644	0.74
401_A	453_I	0.644	0.74
336_L	340_V	0.642	0.74
83_I	90_A	0.641	0.74
80_R	84_C	0.639	0.74
61_A	71_E	0.638	0.74
69_A	75_V	0.637	0.74
330_V	334_F	0.636	0.73
177_A	183_F	0.636	0.73
384_D	460_G	0.635	0.73
61_A	65_M	0.634	0.73
256_L	259_R	0.632	0.73
57_N	67_A	0.630	0.73
355_R	359_T	0.630	0.73
460_G	493_N	0.629	0.73
371_Q	438_I	0.629	0.73
414_R	432_V	0.627	0.72
254_R	258_W	0.626	0.72
369_L	469_K	0.626	0.72
301_L	305_I	0.626	0.72
462_S	482_D	0.626	0.72
335_R	339_N	0.625	0.72
412_S	446_I	0.625	0.72
234_G	254_R	0.624	0.72
299_V	307_Y	0.624	0.72
287_V	295_G	0.624	0.72
283_L	300_S	0.623	0.72
271_G	275_I	0.623	0.72
465_I	484_R	0.622	0.72
58_Q	62_A	0.619	0.71
261_L	299_V	0.618	0.71
233_K	237_L	0.618	0.71
397_E	457_K	0.617	0.71
392_T	479_K	0.616	0.71
110_L	131_D	0.615	0.71
61_A	70_A	0.614	0.71
401_A	418_Y	0.614	0.71
57_N	61_A	0.614	0.71
422_L	466_Y	0.613	0.71
73_S	77_P	0.612	0.71
383_M	457_K	0.612	0.71
353_Y	419_A	0.612	0.71
322_T	329_M	0.611	0.70
293_L	323_A	0.610	0.70
223_L	226_V	0.609	0.70
73_S	76_S	0.608	0.70
257_L	309_I	0.606	0.70
291_H	295_G	0.606	0.70
130_F	167_F	0.606	0.70
275_I	278_Q	0.605	0.70
210_Y	219_V	0.605	0.70
160_L	163_R	0.604	0.70
79_Q	82_A	0.603	0.69
418_Y	430_I	0.603	0.69
203_R	210_Y	0.603	0.69
61_A	64_V	0.602	0.69
227_Y	234_G	0.602	0.69
270_S	446_I	0.602	0.69
276_I	282_N	0.601	0.69
376_V	430_I	0.601	0.69
257_L	323_A	0.601	0.69
61_A	69_A	0.601	0.69
80_R	85_E	0.600	0.69
91_N	94_H	0.596	0.69
461_F	485_L	0.595	0.68
83_I	93_T	0.594	0.68
346_S	351_G	0.594	0.68
322_T	328_N	0.592	0.68
425_D	453_I	0.591	0.68
126_L	130_F	0.591	0.68
424_G	462_S	0.590	0.68
337_Y	422_L	0.590	0.68
414_R	434_S	0.590	0.68
396_Q	400_L	0.589	0.68
325_I	330_V	0.589	0.68
61_A	72_Q	0.589	0.68
62_A	70_A	0.588	0.68
63_H	69_A	0.588	0.68
79_Q	91_N	0.588	0.68
393_L	453_I	0.586	0.67
84_C	88_E	0.586	0.67
61_A	66_R	0.586	0.67
409_I	429_I	0.585	0.67
383_M	477_A	0.585	0.67
123_A	134_V	0.583	0.67
210_Y	225_P	0.583	0.67
396_Q	478_Y	0.582	0.67
253_D	261_L	0.581	0.67
340_V	343_E	0.580	0.66
477_A	480_A	0.580	0.66
344_N	386_L	0.578	0.66
98_L	101_H	0.578	0.66
116_D	119_T	0.578	0.66
278_Q	282_N	0.577	0.66
382_D	390_N	0.576	0.66
80_R	83_I	0.575	0.66
253_D	258_W	0.574	0.66
157_Y	169_E	0.573	0.66
102_K	107_R	0.572	0.65
308_F	327_L	0.572	0.65
258_W	271_G	0.571	0.65
225_P	237_L	0.571	0.65
157_Y	164_Y	0.570	0.65
197_E	203_R	0.570	0.65
118_D	122_E	0.570	0.65
100_A	104_P	0.569	0.65
369_L	468_M	0.568	0.65
72_Q	76_S	0.568	0.65
253_D	257_L	0.568	0.65
368_K	433_D	0.566	0.65
60_I	76_S	0.566	0.65
349_M	355_R	0.566	0.65
174_E	180_N	0.566	0.65
387_K	462_S	0.565	0.64
423_G	489_K	0.564	0.64
346_S	389_I	0.564	0.64
65_M	75_V	0.563	0.64
124_A	127_L	0.562	0.64
64_V	72_Q	0.562	0.64
384_D	395_H	0.561	0.64
323_A	326_L	0.560	0.64
386_L	482_D	0.560	0.64
381_I	422_L	0.559	0.64
395_H	398_G	0.558	0.63
362_L	365_R	0.557	0.63
80_R	90_A	0.557	0.63
412_S	445_R	0.556	0.63
59_S	75_V	0.556	0.63
384_D	494_S	0.555	0.63
160_L	172_N	0.554	0.63
414_R	439_A	0.554	0.63
355_R	395_H	0.554	0.63
62_A	73_S	0.553	0.63
488_N	494_S	0.553	0.63
70_A	75_V	0.552	0.63
65_M	81_R	0.552	0.63
114_S	118_D	0.551	0.63
346_S	357_I	0.551	0.63
202_G	212_D	0.548	0.62
65_M	70_A	0.548	0.62
265_L	269_D	0.547	0.62
257_L	279_S	0.547	0.62
219_V	223_L	0.547	0.62
343_E	428_C	0.546	0.62
394_G	398_G	0.545	0.62
227_Y	233_K	0.545	0.62
391_D	399_D	0.545	0.62
206_L	222_L	0.543	0.61
339_N	478_Y	0.543	0.61
395_H	462_S	0.542	0.61
300_S	306_L	0.542	0.61
434_S	467_A	0.542	0.61
470_E	477_A	0.542	0.61
233_K	328_N	0.541	0.61
223_L	227_Y	0.540	0.61
117_C	121_V	0.540	0.61
162_D	172_N	0.539	0.61
335_R	338_Q	0.539	0.61
377_M	465_I	0.539	0.61
349_M	391_D	0.539	0.61
380_A	420_I	0.538	0.61
210_Y	213_Q	0.538	0.61
344_N	354_N	0.537	0.61
436_P	465_I	0.537	0.61
444_E	451_Q	0.535	0.60
346_S	493_N	0.534	0.60
88_E	95_G	0.534	0.60
398_G	426_E	0.534	0.60
353_Y	408_A	0.533	0.60
107_R	111_Q	0.533	0.60
203_R	206_L	0.532	0.60
464_G	486_Y	0.532	0.60
207_S	220_M	0.531	0.60
220_M	223_L	0.531	0.60
232_L	235_I	0.529	0.59
422_L	446_I	0.529	0.59
468_M	480_A	0.529	0.59
344_N	443_P	0.528	0.59
336_L	343_E	0.527	0.59
261_L	268_T	0.527	0.59
295_G	300_S	0.527	0.59
425_D	492_K	0.526	0.59
154_F	158_L	0.526	0.59
202_G	225_P	0.522	0.58
159_D	162_D	0.522	0.58
450_L	459_I	0.522	0.58
177_A	181_W	0.521	0.58
57_N	62_A	0.520	0.58
243_N	254_R	0.520	0.58
176_F	179_N	0.520	0.58
301_L	304_D	0.519	0.58
359_T	381_I	0.519	0.58
166_Y	170_P	0.519	0.58
169_E	173_V	0.518	0.58
391_D	425_D	0.517	0.58
478_Y	481_S	0.517	0.58
125_A	128_P	0.517	0.58
263_V	266_T	0.515	0.57
361_E	365_R	0.515	0.57
376_V	385_K	0.515	0.57
199_V	203_R	0.515	0.57
283_L	286_Y	0.514	0.57
130_F	133_A	0.514	0.57
174_E	177_A	0.514	0.57
287_V	301_L	0.512	0.57
88_E	91_N	0.512	0.57
167_F	178_M	0.512	0.57
241_N	244_N	0.512	0.57
183_F	215_T	0.511	0.57
344_N	485_L	0.511	0.57
97_N	101_H	0.509	0.57
257_L	260_F	0.508	0.56
195_D	199_V	0.508	0.56
387_K	399_D	0.508	0.56
62_A	76_S	0.507	0.56
120_I	132_Q	0.506	0.56
345_I	477_A	0.505	0.56
210_Y	220_M	0.505	0.56
65_M	76_S	0.505	0.56
231_Q	243_N	0.504	0.56
89_S	94_H	0.504	0.56
221_S	239_D	0.504	0.56
201_T	226_V	0.503	0.56
344_N	353_Y	0.503	0.56
69_A	76_S	0.503	0.56
242_K	245_L	0.502	0.56
230_G	235_I	0.501	0.55
257_L	293_L	0.501	0.55
372_S	434_S	0.501	0.55
64_V	73_S	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w25A	2	0.7621	100	0.521	Contact Map
3ezuA	2	0.6552	100	0.54	Contact Map
4j40A	2	0	100	0.552	Contact Map
3pjxA	1	0.3407	100	0.556	Contact Map
4h54A	2	0.5202	100	0.567	Contact Map
4rnhA	2	0.2984	100	0.573	Contact Map
3ignA	1	0.3145	100	0.576	Contact Map
3i5cA	2	0.3669	100	0.581	Contact Map
3qyyA	1	0.3024	100	0.581	Contact Map
3breA	4	0.5867	100	0.581	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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