YEAI - ECOLI - GREMLIN Contacts

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YEAI - Inner membrane protein YeaI

UniProt:	P76236	Sequences: MIQSTRISMGLFFKYFLSLTKIDPGQNYISLPSIKSSTHIALLFMVSMGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNAVIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYNADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLASLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTISIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG13495
Length:	491 (408)
Sequences:	4623 (4174)
Seq/√Len:	206.7

ECOLI - YEAI YCDT YEGE YFEA ADRA YEDQ YFGF YNEF YDAM DOSC DOSP YEAJ GMR YFIN YEAP YLIF CSRD
BACSU - YKOW YTRP YHCK YDAK

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
396_R	399_D	7.556	1.00
326_K	330_H	5.628	1.00
361_M	452_I	5.083	1.00
346_V	464_I	4.204	1.00
361_M	425_A	4.178	1.00
367_Q	483_G	3.921	1.00
359_C	456_F	3.646	1.00
426_E	429_R	3.599	1.00
337_Y	341_Y	3.204	1.00
342_F	410_G	3.185	1.00
317_I	321_L	3.083	1.00
458_T	461_T	2.926	1.00
413_F	424_I	2.890	1.00
395_I	401_L	2.858	1.00
342_F	402_A	2.834	1.00
359_C	421_A	2.765	1.00
382_K	385_V	2.737	1.00
433_E	484_N	2.694	1.00
404_L	410_G	2.594	1.00
349_L	352_R	2.549	1.00
478_A	487_I	2.515	1.00
371_I	383_V	2.487	1.00
463_N	466_L	2.441	1.00
365_I	387_I	2.407	1.00
417_N	420_Q	2.389	1.00
362_L	475_L	2.377	1.00
321_L	324_S	2.372	1.00
472_D	476_R	2.369	1.00
336_I	388_V	2.342	1.00
390_I	435_L	2.324	1.00
365_I	450_I	2.308	1.00
449_T	484_N	2.239	1.00
363_V	450_I	2.237	1.00
391_I	401_L	2.231	1.00
432_V	450_I	2.172	1.00
345_S	400_I	2.132	1.00
310_V	313_L	2.130	1.00
313_L	317_I	2.126	1.00
386_S	389_D	2.112	1.00
377_H	472_D	2.102	1.00
341_Y	345_S	2.054	1.00
337_Y	400_I	2.035	1.00
306_K	313_L	2.024	1.00
373_A	476_R	2.014	1.00
336_I	401_L	2.008	1.00
429_R	486_V	1.953	1.00
345_S	348_S	1.952	1.00
426_E	430_K	1.930	1.00
369_K	476_R	1.921	1.00
369_K	373_A	1.889	1.00
307_L	310_V	1.876	1.00
481_E	487_I	1.864	1.00
367_Q	407_E	1.861	1.00
389_D	392_Q	1.860	1.00
378_R	469_T	1.858	1.00
454_T	486_V	1.849	1.00
366_N	451_S	1.849	1.00
407_E	449_T	1.840	1.00
377_H	476_R	1.831	1.00
429_R	433_E	1.822	1.00
341_Y	400_I	1.817	1.00
309_V	313_L	1.807	1.00
461_T	470_E	1.759	1.00
478_A	485_K	1.741	1.00
386_S	390_I	1.739	1.00
363_V	452_I	1.737	1.00
386_S	436_T	1.730	1.00
317_I	320_E	1.683	1.00
372_N	380_G	1.669	1.00
405_E	408_V	1.663	1.00
307_L	313_L	1.649	1.00
422_K	426_E	1.649	1.00
390_I	436_T	1.634	1.00
435_L	438_F	1.632	1.00
405_E	476_R	1.622	1.00
306_K	315_Y	1.613	1.00
310_V	314_I	1.612	1.00
477_E	480_S	1.603	1.00
406_G	476_R	1.581	1.00
364_D	476_R	1.579	1.00
425_A	452_I	1.571	1.00
387_I	391_I	1.552	1.00
399_D	427_R	1.538	1.00
210_L	214_L	1.537	1.00
329_V	344_N	1.530	1.00
383_V	436_T	1.525	1.00
474_A	478_A	1.524	1.00
387_I	432_V	1.522	1.00
314_I	317_I	1.521	1.00
306_K	310_V	1.518	1.00
401_L	411_L	1.511	1.00
371_I	446_E	1.504	1.00
318_F	321_L	1.502	1.00
405_E	472_D	1.501	1.00
477_E	487_I	1.496	1.00
383_V	448_M	1.494	1.00
373_A	472_D	1.484	1.00
477_E	481_E	1.481	1.00
361_M	411_L	1.476	1.00
455_V	467_V	1.467	1.00
303_V	313_L	1.460	1.00
325_S	329_V	1.456	1.00
332_V	340_R	1.450	1.00
361_M	413_F	1.449	1.00
421_A	425_A	1.440	1.00
457_S	467_V	1.436	1.00
365_I	449_T	1.423	1.00
364_D	479_K	1.418	1.00
424_I	427_R	1.417	1.00
388_V	401_L	1.413	1.00
410_G	468_M	1.408	1.00
333_L	339_R	1.401	1.00
342_F	412_L	1.401	1.00
382_K	386_S	1.400	1.00
323_L	327_L	1.400	1.00
390_I	438_F	1.394	1.00
163_Y	167_Q	1.382	1.00
481_E	485_K	1.373	1.00
358_F	457_S	1.363	1.00
303_V	306_K	1.357	1.00
344_N	348_S	1.352	1.00
343_F	465_S	1.342	1.00
413_F	421_A	1.313	1.00
306_K	314_I	1.301	1.00
408_V	476_R	1.295	1.00
339_R	381_D	1.292	1.00
346_V	412_L	1.287	1.00
164_I	167_Q	1.282	1.00
377_H	408_V	1.276	1.00
429_R	484_N	1.265	1.00
307_L	314_I	1.265	1.00
404_L	468_M	1.260	1.00
406_G	472_D	1.259	1.00
309_V	317_I	1.235	1.00
430_K	434_L	1.234	1.00
342_F	346_V	1.228	1.00
478_A	482_G	1.225	1.00
408_V	472_D	1.224	1.00
349_L	414_T	1.212	1.00
369_K	479_K	1.201	1.00
383_V	407_E	1.193	1.00
364_D	377_H	1.185	1.00
429_R	452_I	1.177	1.00
449_T	482_G	1.177	1.00
334_T	384_L	1.177	1.00
345_S	349_L	1.174	1.00
369_K	472_D	1.171	1.00
395_I	411_L	1.166	1.00
313_L	318_F	1.158	1.00
67_L	71_C	1.157	1.00
321_L	325_S	1.144	1.00
366_N	483_G	1.141	1.00
407_E	429_R	1.135	1.00
358_F	467_V	1.129	1.00
347_E	464_I	1.126	1.00
369_K	408_V	1.112	1.00
67_L	70_F	1.108	1.00
369_K	406_G	1.108	1.00
349_L	358_F	1.106	1.00
369_K	372_N	1.094	1.00
394_S	427_R	1.088	1.00
394_S	431_N	1.085	1.00
314_I	318_F	1.085	1.00
359_C	454_T	1.085	1.00
337_Y	402_A	1.084	1.00
399_D	424_I	1.082	1.00
402_A	410_G	1.078	1.00
407_E	484_N	1.065	1.00
166_R	169_S	1.063	1.00
431_N	434_L	1.058	1.00
377_H	479_K	1.054	1.00
407_E	475_L	1.047	1.00
364_D	372_N	1.039	1.00
372_N	479_K	1.039	1.00
158_D	164_I	1.028	1.00
357_D	459_G	1.026	1.00
387_I	448_M	1.026	1.00
391_I	395_I	1.025	1.00
395_I	399_D	1.024	1.00
369_K	377_H	1.022	1.00
309_V	315_Y	1.022	1.00
162_F	165_F	1.022	1.00
368_F	384_L	1.021	1.00
373_A	405_E	1.017	1.00
377_H	406_G	1.015	1.00
311_S	314_I	1.013	1.00
396_R	427_R	1.008	1.00
379_V	382_K	1.005	1.00
167_Q	170_F	1.002	1.00
162_F	166_R	1.002	1.00
362_L	410_G	1.002	1.00
367_Q	475_L	0.999	1.00
306_K	309_V	0.997	1.00
176_L	180_C	0.996	1.00
458_T	470_E	0.992	1.00
372_N	408_V	0.992	1.00
373_A	377_H	0.989	1.00
303_V	307_L	0.988	1.00
421_A	454_T	0.986	1.00
469_T	473_K	0.981	1.00
327_L	340_R	0.978	1.00
407_E	483_G	0.976	1.00
380_G	408_V	0.976	1.00
330_H	337_Y	0.966	1.00
365_I	475_L	0.965	1.00
373_A	408_V	0.964	1.00
247_C	251_F	0.963	1.00
372_N	407_E	0.956	0.99
396_R	424_I	0.942	0.99
366_N	482_G	0.940	0.99
367_Q	370_R	0.936	0.99
356_K	415_E	0.934	0.99
316_N	319_Q	0.930	0.99
158_D	162_F	0.925	0.99
140_V	143_H	0.924	0.99
247_C	250_A	0.922	0.99
475_L	482_G	0.921	0.99
343_F	347_E	0.916	0.99
141_I	144_K	0.911	0.99
364_D	408_V	0.910	0.99
373_A	406_G	0.908	0.99
425_A	454_T	0.905	0.99
362_L	407_E	0.903	0.99
353_P	457_S	0.900	0.99
309_V	314_I	0.899	0.99
285_L	289_E	0.896	0.99
311_S	315_Y	0.894	0.99
213_N	216_S	0.894	0.99
475_L	483_G	0.892	0.99
108_M	111_K	0.891	0.99
460_D	488_I	0.888	0.99
336_I	391_I	0.884	0.99
457_S	461_T	0.877	0.99
307_L	317_I	0.876	0.99
313_L	321_L	0.873	0.99
450_I	475_L	0.872	0.99
386_S	435_L	0.871	0.99
159_V	162_F	0.869	0.99
455_V	470_E	0.867	0.99
408_V	479_K	0.863	0.99
425_A	482_G	0.863	0.99
283_L	286_T	0.862	0.99
274_C	277_S	0.859	0.99
476_R	479_K	0.857	0.99
340_R	407_E	0.855	0.99
163_Y	166_R	0.854	0.99
208_P	211_A	0.853	0.99
341_Y	344_N	0.853	0.99
377_H	405_E	0.851	0.99
370_R	374_Q	0.846	0.99
454_T	488_I	0.843	0.99
309_V	312_F	0.837	0.99
162_F	175_S	0.836	0.99
315_Y	318_F	0.834	0.99
407_E	435_L	0.834	0.99
104_I	108_M	0.834	0.99
98_F	101_N	0.833	0.99
364_D	380_G	0.830	0.99
329_V	337_Y	0.822	0.98
68_I	72_I	0.820	0.98
407_E	485_K	0.819	0.98
308_F	313_L	0.819	0.98
316_N	320_E	0.816	0.98
363_V	391_I	0.816	0.98
387_I	436_T	0.813	0.98
371_I	374_Q	0.813	0.98
385_V	389_D	0.811	0.98
399_D	413_F	0.811	0.98
288_D	291_N	0.810	0.98
368_F	372_N	0.807	0.98
425_A	486_V	0.807	0.98
378_R	465_S	0.806	0.98
352_R	414_T	0.804	0.98
369_K	405_E	0.802	0.98
472_D	475_L	0.801	0.98
313_L	316_N	0.799	0.98
382_K	442_Y	0.799	0.98
67_L	74_T	0.793	0.98
325_S	344_N	0.793	0.98
328_A	338_N	0.790	0.98
159_V	163_Y	0.789	0.98
72_I	75_L	0.785	0.98
300_G	306_K	0.783	0.98
206_V	209_L	0.783	0.98
350_L	457_S	0.782	0.98
301_I	306_K	0.781	0.98
175_S	178_L	0.780	0.98
163_Y	176_L	0.779	0.98
422_K	486_V	0.778	0.98
302_E	306_K	0.777	0.98
344_N	400_I	0.777	0.98
380_G	479_K	0.776	0.98
451_S	476_R	0.775	0.98
394_S	399_D	0.774	0.98
166_R	175_S	0.773	0.98
364_D	369_K	0.766	0.98
432_V	448_M	0.763	0.97
364_D	406_G	0.762	0.97
407_E	436_T	0.761	0.97
310_V	317_I	0.761	0.97
383_V	438_F	0.761	0.97
63_L	67_L	0.758	0.97
363_V	411_L	0.756	0.97
364_D	373_A	0.755	0.97
166_R	170_F	0.754	0.97
270_I	282_L	0.753	0.97
329_V	341_Y	0.749	0.97
175_S	179_F	0.749	0.97
408_V	451_S	0.749	0.97
308_F	311_S	0.747	0.97
377_H	407_E	0.746	0.97
250_A	253_L	0.746	0.97
335_N	385_V	0.745	0.97
404_L	407_E	0.745	0.97
371_I	407_E	0.742	0.97
320_E	323_L	0.741	0.97
178_L	181_Y	0.740	0.97
311_S	317_I	0.739	0.97
438_F	446_E	0.739	0.97
302_E	305_S	0.739	0.97
303_V	310_V	0.732	0.97
324_S	327_L	0.731	0.97
64_L	68_I	0.731	0.97
303_V	309_V	0.729	0.97
395_I	424_I	0.727	0.97
120_P	123_I	0.724	0.97
443_D	446_E	0.723	0.97
253_L	257_I	0.722	0.97
323_L	326_K	0.721	0.96
283_L	287_L	0.720	0.96
430_K	433_E	0.720	0.96
322_Q	325_S	0.718	0.96
271_A	278_L	0.717	0.96
129_L	138_T	0.717	0.96
281_N	289_E	0.712	0.96
372_N	406_G	0.711	0.96
330_H	341_Y	0.708	0.96
278_L	283_L	0.705	0.96
242_T	249_W	0.702	0.96
230_P	233_H	0.697	0.96
306_K	317_I	0.697	0.96
451_S	482_G	0.693	0.96
251_F	255_F	0.687	0.95
317_I	324_S	0.685	0.95
394_S	428_M	0.685	0.95
362_L	468_M	0.684	0.95
422_K	488_I	0.683	0.95
330_H	335_N	0.682	0.95
369_K	380_G	0.681	0.95
342_F	360_V	0.680	0.95
432_V	436_T	0.680	0.95
107_F	111_K	0.679	0.95
156_S	159_V	0.679	0.95
362_L	404_L	0.679	0.95
411_L	428_M	0.678	0.95
451_S	478_A	0.677	0.95
375_W	444_V	0.675	0.95
416_L	420_Q	0.675	0.95
70_F	74_T	0.674	0.95
332_V	404_L	0.674	0.95
365_I	472_D	0.673	0.95
461_T	466_L	0.673	0.95
137_E	141_I	0.672	0.95
244_I	248_L	0.672	0.95
284_L	287_L	0.670	0.95
174_T	181_Y	0.669	0.95
300_G	303_V	0.669	0.95
281_N	284_L	0.669	0.95
71_C	74_T	0.668	0.95
173_L	180_C	0.667	0.95
395_I	428_M	0.666	0.95
302_E	313_L	0.666	0.95
368_F	479_K	0.665	0.95
206_V	211_A	0.665	0.95
160_S	163_Y	0.663	0.94
366_N	484_N	0.663	0.94
369_K	475_L	0.662	0.94
137_E	140_V	0.662	0.94
161_I	164_I	0.661	0.94
328_A	369_K	0.661	0.94
308_F	314_I	0.659	0.94
407_E	476_R	0.657	0.94
466_L	469_T	0.656	0.94
388_V	391_I	0.652	0.94
427_R	431_N	0.652	0.94
278_L	281_N	0.652	0.94
274_C	283_L	0.651	0.94
206_V	210_L	0.651	0.94
204_F	208_P	0.650	0.94
345_S	402_A	0.650	0.94
165_F	176_L	0.650	0.94
377_H	380_G	0.649	0.94
230_P	237_W	0.649	0.94
194_T	198_L	0.648	0.94
209_L	213_N	0.645	0.94
170_F	178_L	0.644	0.94
330_H	407_E	0.643	0.93
211_A	216_S	0.643	0.93
365_I	368_F	0.643	0.93
368_F	478_A	0.642	0.93
358_F	412_L	0.642	0.93
375_W	383_V	0.641	0.93
378_R	468_M	0.641	0.93
138_T	141_I	0.640	0.93
170_F	173_L	0.640	0.93
74_T	78_E	0.640	0.93
167_Q	171_I	0.639	0.93
328_A	472_D	0.637	0.93
170_F	175_S	0.637	0.93
245_L	248_L	0.635	0.93
345_S	412_L	0.634	0.93
270_I	274_C	0.634	0.93
75_L	79_N	0.634	0.93
275_L	278_L	0.633	0.93
349_L	353_P	0.632	0.93
163_Y	177_A	0.630	0.93
366_N	449_T	0.630	0.93
426_E	486_V	0.628	0.93
407_E	479_K	0.628	0.93
346_V	350_L	0.627	0.93
390_I	446_E	0.625	0.93
210_L	216_S	0.625	0.93
266_L	270_I	0.624	0.92
220_D	223_L	0.623	0.92
438_F	442_Y	0.622	0.92
407_E	486_V	0.622	0.92
380_G	406_G	0.622	0.92
237_W	241_Y	0.619	0.92
455_V	458_T	0.619	0.92
75_L	78_E	0.619	0.92
64_L	67_L	0.618	0.92
379_V	446_E	0.618	0.92
380_G	407_E	0.617	0.92
327_L	338_N	0.617	0.92
176_L	179_F	0.617	0.92
119_L	122_L	0.617	0.92
165_F	170_F	0.616	0.92
245_L	249_W	0.616	0.92
425_A	429_R	0.614	0.92
174_T	180_C	0.613	0.92
157_N	165_F	0.612	0.92
157_N	160_S	0.608	0.91
307_L	312_F	0.607	0.91
437_G	445_P	0.607	0.91
140_V	144_K	0.607	0.91
310_V	320_E	0.606	0.91
72_I	78_E	0.606	0.91
377_H	475_L	0.606	0.91
314_I	321_L	0.605	0.91
457_S	460_D	0.604	0.91
460_D	470_E	0.603	0.91
350_L	464_I	0.602	0.91
424_I	428_M	0.601	0.91
366_N	475_L	0.600	0.91
361_M	454_T	0.600	0.91
364_D	483_G	0.599	0.91
282_L	288_D	0.599	0.91
339_R	343_F	0.597	0.91
394_S	424_I	0.596	0.91
280_C	284_L	0.595	0.91
350_L	358_F	0.595	0.91
375_W	473_K	0.595	0.91
383_V	437_G	0.593	0.90
370_R	407_E	0.592	0.90
277_S	284_L	0.591	0.90
158_D	170_F	0.590	0.90
235_A	238_G	0.590	0.90
365_I	469_T	0.590	0.90
205_L	208_P	0.589	0.90
175_S	182_G	0.589	0.90
164_I	181_Y	0.588	0.90
127_A	130_S	0.588	0.90
302_E	307_L	0.588	0.90
265_E	268_P	0.587	0.90
380_G	476_R	0.587	0.90
429_R	482_G	0.586	0.90
341_Y	349_L	0.583	0.90
306_K	311_S	0.582	0.90
167_Q	177_A	0.581	0.90
66_T	70_F	0.580	0.89
286_T	290_Y	0.580	0.89
156_S	162_F	0.578	0.89
360_V	468_M	0.577	0.89
451_S	479_K	0.576	0.89
360_V	410_G	0.576	0.89
285_L	288_D	0.576	0.89
278_L	284_L	0.575	0.89
372_N	377_H	0.575	0.89
169_S	176_L	0.575	0.89
428_M	484_N	0.575	0.89
419_A	422_K	0.573	0.89
303_V	314_I	0.572	0.89
228_Y	231_D	0.572	0.89
249_W	253_L	0.570	0.89
283_L	290_Y	0.569	0.89
86_P	89_N	0.569	0.89
272_L	276_A	0.569	0.89
173_L	177_A	0.569	0.89
159_V	167_Q	0.567	0.88
280_C	286_T	0.567	0.88
367_Q	449_T	0.566	0.88
156_S	168_L	0.566	0.88
258_M	261_R	0.566	0.88
208_P	212_H	0.565	0.88
168_L	176_L	0.565	0.88
95_V	99_F	0.564	0.88
253_L	256_I	0.562	0.88
458_T	467_V	0.562	0.88
155_K	162_F	0.561	0.88
475_L	478_A	0.561	0.88
306_K	312_F	0.561	0.88
275_L	279_C	0.560	0.88
138_T	144_K	0.559	0.88
96_A	99_F	0.559	0.88
276_A	279_C	0.559	0.88
210_L	213_N	0.558	0.88
462_R	470_E	0.558	0.88
209_L	212_H	0.558	0.88
437_G	443_D	0.556	0.87
276_A	284_L	0.555	0.87
339_R	402_A	0.554	0.87
237_W	240_N	0.553	0.87
470_E	473_K	0.553	0.87
324_S	329_V	0.552	0.87
198_L	216_S	0.551	0.87
271_A	282_L	0.551	0.87
206_V	214_L	0.551	0.87
277_S	280_C	0.551	0.87
308_F	315_Y	0.550	0.87
167_Q	208_P	0.550	0.87
312_F	315_Y	0.550	0.87
103_V	115_N	0.549	0.87
342_F	468_M	0.548	0.87
248_L	252_L	0.548	0.87
91_L	94_V	0.547	0.87
320_E	327_L	0.546	0.86
349_L	412_L	0.546	0.86
244_I	247_C	0.544	0.86
70_F	75_L	0.542	0.86
195_G	206_V	0.542	0.86
167_Q	175_S	0.542	0.86
343_F	402_A	0.541	0.86
353_P	358_F	0.540	0.86
328_A	336_I	0.540	0.86
420_Q	423_I	0.538	0.86
131_G	145_P	0.538	0.86
279_C	282_L	0.538	0.86
64_L	71_C	0.537	0.86
331_D	381_D	0.537	0.86
332_V	337_Y	0.536	0.85
466_L	470_E	0.536	0.85
407_E	482_G	0.536	0.85
390_I	428_M	0.534	0.85
162_F	174_T	0.534	0.85
387_I	450_I	0.533	0.85
266_L	269_L	0.533	0.85
106_L	109_L	0.532	0.85
164_I	175_S	0.532	0.85
92_M	95_V	0.532	0.85
88_M	91_L	0.530	0.85
234_T	238_G	0.528	0.85
332_V	338_N	0.526	0.84
170_F	174_T	0.526	0.84
178_L	183_K	0.525	0.84
329_V	345_S	0.525	0.84
390_I	394_S	0.523	0.84
371_I	401_L	0.523	0.84
368_F	451_S	0.523	0.84
270_I	279_C	0.523	0.84
304_S	311_S	0.522	0.84
174_T	177_A	0.522	0.84
176_L	181_Y	0.520	0.84
364_D	403_R	0.520	0.84
391_I	428_M	0.519	0.84
364_D	381_D	0.518	0.83
451_S	472_D	0.516	0.83
73_T	78_E	0.516	0.83
248_L	255_F	0.516	0.83
274_C	281_N	0.515	0.83
359_C	416_L	0.514	0.83
250_A	254_F	0.514	0.83
94_V	98_F	0.514	0.83
329_V	332_V	0.513	0.83
231_D	235_A	0.513	0.83
198_L	209_L	0.513	0.83
130_S	137_E	0.513	0.83
396_R	416_L	0.513	0.83
400_I	412_L	0.512	0.83
368_F	407_E	0.512	0.83
250_A	256_I	0.511	0.83
193_K	196_I	0.511	0.83
196_I	199_L	0.510	0.83
205_L	214_L	0.510	0.83
418_S	456_F	0.510	0.83
235_A	239_I	0.509	0.82
194_T	197_L	0.508	0.82
345_S	414_T	0.507	0.82
414_T	421_A	0.507	0.82
123_I	127_A	0.507	0.82
81_N	88_M	0.506	0.82
72_I	76_Y	0.506	0.82
365_I	384_L	0.506	0.82
271_A	276_A	0.505	0.82
331_D	339_R	0.505	0.82
407_E	437_G	0.505	0.82
278_L	285_L	0.503	0.82
212_H	215_S	0.503	0.82
128_F	131_G	0.502	0.82
278_L	282_L	0.501	0.81
330_H	404_L	0.501	0.81
158_D	174_T	0.501	0.81
405_E	479_K	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1w25A	2	0.6701	100	0.494	Contact Map
4j40A	2	0	100	0.494	Contact Map
3pjxA	1	0.3585	100	0.502	Contact Map
4rnhA	2	0.3177	100	0.508	Contact Map
3ezuA	2	0.6721	100	0.517	Contact Map
4h54A	2	0.5519	100	0.521	Contact Map
3mtkA	2	0.3238	100	0.523	Contact Map
3ignA	1	0.334	100	0.523	Contact Map
3i5cA	2	0.3931	100	0.524	Contact Map
3tvkA	1	0.334	100	0.535	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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