GREMLIN Database
YNJB - Protein YnjB
UniProt: P76223 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14004
Length: 388 (329)
Sequences: 34992 (27551)
Seq/√Len: 1518.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
159_R286_Y3.3991.00
36_W66_K3.1261.00
114_Q310_S3.0331.00
34_T66_K2.9011.00
160_D284_S2.8101.00
173_L233_V2.7811.00
115_T142_Q2.5861.00
15_S18_T2.5421.00
14_F17_A2.4031.00
63_I312_A2.3761.00
177_K237_Y2.3621.00
56_E319_F2.3391.00
58_K64_N2.3361.00
61_Y315_V2.3251.00
34_T64_N2.2821.00
168_T171_A2.2721.00
232_D236_P2.2631.00
322_S325_A2.2561.00
13_L16_L2.2351.00
233_V237_Y2.2341.00
229_Q233_V2.1571.00
56_E59_T2.1261.00
16_L19_H2.0861.00
222_R226_P2.0781.00
315_V318_N2.0621.00
75_D78_K2.0461.00
18_T21_S2.0101.00
56_E328_R2.0071.00
17_A20_A2.0061.00
327_L331_D1.9821.00
51_D55_G1.9621.00
19_H22_D1.9401.00
174_E178_A1.9371.00
36_W68_V1.9341.00
56_E60_H1.9291.00
157_A286_Y1.9271.00
309_A312_A1.9251.00
159_R163_P1.9201.00
95_D309_A1.9051.00
161_V262_R1.8961.00
52_W55_G1.8961.00
57_M315_V1.8101.00
117_W142_Q1.8071.00
20_A23_W1.8041.00
55_G59_T1.7951.00
113_L302_T1.7801.00
162_T263_L1.7391.00
225_A229_Q1.7331.00
58_K61_Y1.7271.00
230_Y233_V1.7261.00
226_P229_Q1.7191.00
348_D352_E1.6961.00
47_N51_D1.6941.00
248_S251_R1.6911.00
135_E138_S1.6661.00
138_S143_G1.6631.00
311_A315_V1.6601.00
171_A174_E1.6581.00
54_S316_V1.6581.00
57_M61_Y1.6541.00
54_S58_K1.6451.00
114_Q305_A1.6201.00
72_D75_D1.6101.00
255_L260_T1.6031.00
38_N83_E1.6001.00
173_L177_K1.6001.00
97_L304_P1.5891.00
145_E300_F1.5871.00
174_E177_K1.5791.00
323_P327_L1.5731.00
310_S314_K1.5691.00
33_Q312_A1.5631.00
164_Q167_Q1.5491.00
177_K181_G1.5471.00
328_R332_P1.5441.00
325_A328_R1.5431.00
173_L237_Y1.5411.00
183_V186_P1.5361.00
205_T208_P1.5321.00
60_H322_S1.5201.00
52_W56_E1.4761.00
79_R83_E1.4721.00
328_R331_D1.4671.00
312_A315_V1.4631.00
158_R161_V1.4501.00
55_G58_K1.4491.00
170_Q173_L1.4291.00
129_T132_P1.4261.00
303_I317_A1.4251.00
307_A310_S1.4221.00
39_A67_I1.4111.00
57_M316_V1.3891.00
254_A258_A1.3701.00
126_Y343_P1.3681.00
159_R284_S1.3651.00
157_A288_F1.3621.00
155_F288_F1.3611.00
170_Q174_E1.3601.00
173_L230_Y1.3531.00
167_Q171_A1.3451.00
179_N262_R1.3451.00
229_Q232_D1.3301.00
32_G64_N1.3171.00
57_M319_F1.3141.00
255_L261_L1.3131.00
223_V226_P1.3111.00
96_L313_A1.3081.00
108_K144_A1.2991.00
57_M63_I1.2861.00
173_L234_L1.2851.00
21_S24_Q1.2821.00
348_D351_R1.2581.00
48_R51_D1.2571.00
167_Q291_R1.2541.00
230_Y234_L1.2371.00
54_S67_I1.2331.00
161_V179_N1.2331.00
121_L124_W1.2301.00
120_T123_N1.2261.00
311_A314_K1.2251.00
184_T187_R1.2031.00
96_L316_V1.1961.00
303_I313_A1.1931.00
233_V236_P1.1681.00
222_R225_A1.1611.00
120_T124_W1.1601.00
52_W328_R1.1571.00
183_V187_R1.1571.00
314_K318_N1.1561.00
115_T143_G1.1491.00
118_A122_P1.1301.00
128_D131_L1.1241.00
63_I315_V1.1241.00
119_E122_P1.1221.00
99_V302_T1.1181.00
54_S65_L1.1151.00
137_F300_F1.1141.00
352_E355_Q1.1131.00
154_T287_S1.1091.00
307_A313_A1.1061.00
33_Q309_A1.0951.00
256_L285_S1.0941.00
274_Q277_A1.0941.00
324_D327_L1.0931.00
13_L18_T1.0901.00
123_N318_N1.0871.00
14_F18_T1.0851.00
323_P343_P1.0761.00
162_T175_F1.0701.00
13_L17_A1.0691.00
175_F178_A1.0631.00
176_A263_L1.0571.00
111_N305_A1.0541.00
155_F263_L1.0481.00
251_R254_A1.0471.00
95_D307_A1.0461.00
15_S19_H1.0431.00
37_F301_V1.0431.00
184_T261_L1.0421.00
158_R283_A1.0421.00
84_A93_S1.0371.00
204_L208_P1.0371.00
319_F325_A1.0351.00
158_R284_S1.0211.00
56_E324_D1.0181.00
79_R82_T1.0151.00
57_M312_A1.0131.00
201_L204_L1.0071.00
324_D328_R1.0071.00
156_I266_T1.0061.00
316_V320_L1.0051.00
166_P171_A1.0051.00
119_E314_K1.0031.00
96_L317_A1.0031.00
81_Q110_A0.9991.00
15_S20_A0.9931.00
303_I314_K0.9921.00
172_L176_A0.9921.00
226_P230_Y0.9911.00
349_G352_E0.9911.00
14_F19_H0.9891.00
77_V103_N0.9891.00
52_W332_P0.9811.00
97_L302_T0.9791.00
22_D25_E0.9751.00
17_A21_S0.9741.00
182_T262_R0.9711.00
201_L205_T0.9691.00
60_H324_D0.9671.00
160_D283_A0.9651.00
200_L204_L0.9621.00
125_R128_D0.9581.00
60_H319_F0.9561.00
127_V132_P0.9561.00
106_T110_A0.9551.00
120_T314_K0.9531.00
107_L113_L0.9471.00
23_W26_I0.9461.00
114_Q314_K0.9451.00
126_Y341_L0.9441.00
323_P341_L0.9431.00
127_V131_L0.9421.00
118_A121_L0.9411.00
185_Y188_P0.9401.00
108_K139_V0.9371.00
16_L20_A0.9351.00
175_F263_L0.9311.00
35_V316_V0.9281.00
218_A221_A0.9281.00
303_I307_A0.9271.00
162_T179_N0.9251.00
301_V317_A0.9231.00
80_I97_L0.9211.00
53_V56_E0.9191.00
129_T135_E0.9181.00
191_F195_A0.9161.00
56_E325_A0.9131.00
87_G306_N0.9131.00
35_V312_A0.9101.00
125_R132_P0.9071.00
304_P307_A0.9061.00
178_A181_G0.9041.00
65_L316_V0.9021.00
305_A310_S0.8991.00
93_S304_P0.8971.00
183_V188_P0.8961.00
172_L263_L0.8941.00
273_Q277_A0.8931.00
53_V325_A0.8931.00
32_G62_A0.8901.00
164_Q171_A0.8861.00
145_E302_T0.8851.00
128_D342_D0.8851.00
148_W301_V0.8821.00
266_T270_A0.8791.00
38_N94_V0.8791.00
58_K65_L0.8781.00
221_A225_A0.8751.00
355_Q358_M0.8741.00
176_A180_P0.8701.00
48_R52_W0.8661.00
204_L226_P0.8641.00
105_R109_E0.8621.00
254_A257_K0.8621.00
84_A112_L0.8561.00
113_L144_A0.8551.00
49_Y52_W0.8551.00
201_L206_P0.8541.00
232_D235_H0.8511.00
78_K82_T0.8501.00
327_L344_Q0.8471.00
341_L344_Q0.8451.00
122_P125_R0.8441.00
202_I205_T0.8411.00
18_T22_D0.8311.00
28_N31_K0.8311.00
275_K279_G0.8241.00
157_A165_P0.8241.00
219_T224_T0.8201.00
125_R129_T0.8101.00
126_Y129_T0.8081.00
62_A315_V0.8071.00
351_R355_Q0.8051.00
115_T144_A0.8031.00
160_D163_P0.8021.00
184_T189_P0.7981.00
35_V309_A0.7961.00
119_E124_W0.7921.00
279_G283_A0.7841.00
273_Q276_I0.7811.00
138_S141_T0.7801.00
199_Q203_M0.7791.00
116_G317_A0.7741.00
235_H238_L0.7741.00
221_A224_T0.7731.00
202_I207_D0.7711.00
78_K81_Q0.7701.00
114_Q304_P0.7701.00
301_V320_L0.7661.00
178_A182_T0.7651.00
316_V319_F0.7611.00
279_G282_P0.7611.00
77_V106_T0.7601.00
114_Q303_I0.7591.00
17_A22_D0.7591.00
250_A253_D0.7551.00
169_P173_L0.7541.00
313_A317_A0.7451.00
119_E123_N0.7451.00
186_P189_P0.7421.00
83_E88_R0.7411.00
274_Q278_S0.7371.00
187_R190_D0.7301.00
77_V81_Q0.7271.00
18_T23_W0.7261.00
16_L21_S0.7251.00
276_I279_G0.7231.00
114_Q307_A0.7221.00
179_N263_L0.7201.00
82_T86_A0.7191.00
201_L208_P0.7181.00
177_K180_P0.7181.00
247_P255_L0.7161.00
199_Q202_I0.7131.00
238_L242_G0.7121.00
198_E202_I0.7071.00
168_T292_E0.7061.00
183_V189_P0.7061.00
68_V79_R0.7061.00
151_A297_N0.7051.00
30_A33_Q0.7031.00
156_I287_S0.7031.00
318_N322_S0.7001.00
13_L19_H0.6981.00
252_M264_S0.6961.00
108_K113_L0.6951.00
165_P175_F0.6931.00
205_T209_A0.6891.00
137_F143_G0.6871.00
88_R93_S0.6851.00
337_D340_V0.6841.00
255_L258_A0.6831.00
253_D257_K0.6811.00
201_L224_T0.6791.00
347_P350_Q0.6781.00
165_P288_F0.6771.00
202_I206_P0.6751.00
163_P284_S0.6721.00
27_K30_A0.6711.00
228_W232_D0.6701.00
184_T188_P0.6681.00
343_P346_L0.6681.00
126_Y342_D0.6671.00
104_F145_E0.6641.00
203_M208_P0.6621.00
97_L113_L0.6601.00
173_L176_A0.6601.00
14_F20_A0.6561.00
175_F179_N0.6561.00
165_P171_A0.6551.00
197_L201_L0.6531.00
15_S21_S0.6501.00
347_P351_R0.6491.00
180_P238_L0.6481.00
36_W95_D0.6481.00
192_T195_A0.6471.00
231_L235_H0.6461.00
352_E356_S0.6451.00
209_A215_P0.6451.00
26_I29_E0.6421.00
38_N68_V0.6411.00
156_I272_A0.6381.00
257_K278_S0.6381.00
199_Q205_T0.6381.00
169_P230_Y0.6381.00
118_A124_W0.6361.00
353_S356_S0.6351.00
81_Q106_T0.6351.00
128_D132_P0.6351.00
75_D79_R0.6341.00
98_W301_V0.6331.00
196_F200_L0.6301.00
68_V94_V0.6291.00
157_A162_T0.6281.00
332_P335_W0.6281.00
160_D259_G0.6281.00
36_W39_A0.6271.00
200_L203_M0.6271.00
250_A254_A0.6271.00
346_L351_R0.6271.00
166_P263_L0.6231.00
53_V320_L0.6221.00
127_V321_L0.6211.00
38_N70_L0.6211.00
58_K62_A0.6211.00
156_I285_S0.6201.00
115_T118_A0.6201.00
209_A213_E0.6201.00
135_E139_V0.6191.00
95_D308_N0.6161.00
64_N67_I0.6161.00
315_V319_F0.6151.00
104_F108_K0.6151.00
123_N126_Y0.6141.00
356_S359_P0.6131.00
220_F224_T0.6131.00
220_F225_A0.6131.00
349_G353_S0.6131.00
117_W314_K0.6121.00
61_Y312_A0.6121.00
204_L230_Y0.6111.00
103_N106_T0.6101.00
158_R259_G0.6071.00
247_P251_R0.6041.00
70_L79_R0.6041.00
53_V328_R0.6011.00
176_A237_Y0.6001.00
310_S313_A0.5991.00
129_T342_D0.5981.00
126_Y323_P0.5981.00
191_F194_T0.5971.00
31_K34_T0.5961.00
100_N103_N0.5951.00
350_Q354_L0.5941.00
203_M207_D0.5931.00
157_A263_L0.5911.00
286_Y289_G0.5891.00
19_H23_W0.5871.00
159_R283_A0.5861.00
306_N310_S0.5851.00
155_F265_L0.5841.00
77_V107_L0.5831.00
303_I310_S0.5821.00
99_V107_L0.5821.00
213_E217_D0.5811.00
114_Q306_N0.5811.00
51_D67_I0.5791.00
251_R255_L0.5781.00
117_W143_G0.5781.00
171_A175_F0.5771.00
249_P252_M0.5771.00
37_F96_L0.5761.00
326_Q340_V0.5751.00
202_I208_P0.5741.00
146_S321_L0.5691.00
127_V130_Q0.5671.00
138_S142_Q0.5661.00
326_Q330_A0.5651.00
272_A276_I0.5651.00
176_A179_N0.5631.00
29_E32_G0.5611.00
146_S317_A0.5601.00
58_K63_I0.5581.00
81_Q84_A0.5581.00
203_M206_P0.5571.00
227_L231_L0.5561.00
95_D313_A0.5561.00
354_L357_R0.5551.00
131_L150_G0.5541.00
33_Q62_A0.5531.00
37_F67_I0.5511.00
53_V319_F0.5511.00
162_T165_P0.5501.00
314_K317_A0.5501.00
177_K233_V0.5491.00
151_A299_H0.5491.00
243_K246_P0.5491.00
108_K111_N0.5481.00
24_Q27_K0.5471.00
323_P326_Q0.5431.00
213_E216_D0.5401.00
183_V190_D0.5391.00
223_V227_L0.5371.00
117_W120_T0.5361.00
348_D353_S0.5361.00
149_G299_H0.5361.00
16_L22_D0.5361.00
33_Q63_I0.5351.00
162_T262_R0.5351.00
37_F54_S0.5341.00
76_A97_L0.5331.00
180_P237_Y0.5281.00
19_H24_Q0.5271.00
68_V83_E0.5261.00
166_P175_F0.5221.00
152_Q268_N0.5221.00
198_E201_L0.5221.00
122_P318_N0.5201.00
326_Q341_L0.5201.00
214_A217_D0.5191.00
126_Y131_L0.5191.00
17_A23_W0.5191.00
186_P190_D0.5181.00
194_T198_E0.5171.00
37_F98_W0.5161.00
327_L347_P0.5151.00
218_A224_T0.5151.00
35_V95_D0.5151.00
126_Y130_Q0.5131.00
335_W340_V0.5111.00
54_S64_N0.5101.00
342_D346_L0.5091.00
121_L318_N0.5081.00
116_G303_I0.5061.00
33_Q36_W0.5061.00
126_Y132_P0.5041.00
184_T190_D0.5031.00
171_A176_A0.5021.00
252_M261_L0.5021.00
105_R108_K0.5021.00
192_T196_F0.5021.00
117_W138_S0.5011.00
116_G314_K0.5001.00
112_L115_T0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3uorA 1 0.8763 100 0.21 Contact Map
4r2fA 1 0.8737 100 0.214 Contact Map
2zyoA 1 0.8711 100 0.233 Contact Map
2xd3A 1 0.8557 100 0.24 Contact Map
4mfiA 1 0.8789 100 0.244 Contact Map
4r9fA 1 0.8763 100 0.249 Contact Map
3k01A 1 0.8995 100 0.249 Contact Map
4hw8A 2 0.8608 100 0.25 Contact Map
4r6kA 1 0.8789 100 0.254 Contact Map
3j9pD 4 0 100 0.254 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0115 seconds.