GREMLIN Database
YDIQ - Putative electron transfer flavoprotein subunit YdiQ
UniProt: P76201 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG13976
Length: 254 (240)
Sequences: 3510 (2042)
Seq/√Len: 131.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
152_T167_E4.1601.00
53_E80_S3.6211.00
128_G175_C3.3511.00
103_A106_E3.2251.00
48_A79_H3.2171.00
70_R81_L3.1131.00
145_A156_E2.9471.00
203_Q206_D2.9181.00
107_K202_W2.9151.00
43_A46_Q2.6491.00
56_A73_V2.6251.00
80_S200_N2.5861.00
247_E251_K2.5321.00
2_K53_E2.3811.00
74_L81_L2.3471.00
140_I168_L2.3261.00
115_F131_V2.3001.00
43_A181_N2.2321.00
143_V155_I2.1171.00
49_T184_R2.1171.00
33_I69_V2.0751.00
42_E184_R2.0471.00
143_V174_L2.0191.00
4_I105_I1.9921.00
154_V167_E1.9861.00
168_L172_A1.9811.00
153_L168_L1.9621.00
157_R164_E1.9591.00
41_I78_P1.9261.00
6_C115_F1.8851.00
55_A82_Y1.8841.00
102_A106_E1.8661.00
34_S37_D1.7731.00
147_Q154_V1.7711.00
84_V100_A1.7461.00
113_L137_L1.7261.00
98_A134_I1.7181.00
118_G123_Y1.6991.00
112_L172_A1.6971.00
58_T64_L1.6881.00
241_A244_E1.6821.00
55_A80_S1.6781.00
65_Q71_K1.6591.00
4_I110_F1.6321.00
153_L170_V1.6221.00
156_E165_V1.6191.00
148_R153_L1.6131.00
176_V180_I1.6131.00
244_E247_E1.6041.00
240_E244_E1.5831.00
56_A78_P1.5761.00
54_I78_P1.5691.00
107_K200_N1.5501.00
92_A100_A1.5441.00
62_S85_Q1.5031.00
84_V104_A1.4801.00
50_D147_Q1.4771.00
187_S190_A1.4671.00
105_I113_L1.4401.00
85_Q201_Q1.4231.00
132_G139_V1.4201.00
57_L104_A1.4151.00
82_Y104_A1.3771.00
61_G64_L1.3761.00
154_V165_V1.3081.00
44_A54_I1.3071.00
83_L201_Q1.2771.00
3_I51_D1.2701.00
2_K55_A1.2581.00
152_T169_S1.2561.00
55_A110_F1.2531.00
151_N169_S1.2421.00
65_Q201_Q1.2401.00
137_L173_V1.2381.00
119_S122_L1.2191.00
56_A70_R1.2161.00
74_L197_K1.2101.00
144_S156_E1.2101.00
55_A108_I1.2000.99
149_Q154_V1.1950.99
243_A246_A1.1840.99
43_A180_I1.1720.99
39_N181_N1.1450.99
101_L131_V1.1430.99
111_D151_N1.1410.99
99_K103_A1.1390.99
51_D54_I1.1360.99
58_T83_L1.1330.99
19_T22_Y1.1310.99
202_W207_I1.1300.99
80_S108_I1.1270.99
107_K207_I1.1210.99
43_A146_I1.1130.99
99_K134_I1.1050.99
156_E163_V1.1020.99
33_I73_V1.0970.99
189_K193_G1.0960.99
82_Y202_W1.0940.99
41_I76_R1.0880.99
105_I131_V1.0780.99
45_S190_A1.0780.99
148_R170_V1.0630.99
102_A135_L1.0420.99
17_V25_N1.0410.99
42_E46_Q1.0400.99
48_A52_D1.0390.98
7_F41_I1.0360.98
233_I241_A1.0320.98
45_S76_R1.0270.98
85_Q203_Q1.0240.98
86_D92_A1.0240.98
242_I246_A1.0180.98
7_F73_V1.0170.98
204_A209_W1.0140.98
96_D214_P1.0120.98
36_F117_E1.0100.98
191_I197_K1.0090.98
149_Q152_T1.0050.98
9_L69_V1.0000.98
114_I174_L0.9970.98
42_E183_P0.9870.98
140_I155_I0.9850.98
146_I155_I0.9840.98
62_S65_Q0.9830.98
4_I57_L0.9810.98
129_L139_V0.9720.98
138_P172_A0.9710.98
102_A131_V0.9660.98
95_L99_K0.9510.97
39_N179_D0.9470.97
25_N28_N0.9400.97
6_C131_V0.9360.97
100_A207_I0.9310.97
192_L195_G0.9310.97
38_L76_R0.9310.97
103_A207_I0.9300.97
130_L134_I0.9270.97
43_A145_A0.9230.97
223_V226_Q0.9230.97
114_I176_V0.9220.97
189_K192_L0.9210.97
125_Q129_L0.9120.97
159_L162_D0.9080.96
65_Q83_L0.9080.96
113_L131_V0.9070.96
7_F69_V0.9060.96
4_I108_I0.8970.96
231_H248_H0.8930.96
248_H251_K0.8900.96
45_S49_T0.8860.96
93_L215_L0.8840.96
100_A204_A0.8790.96
59_V97_T0.8770.96
64_L83_L0.8760.96
7_F56_A0.8720.96
76_R183_P0.8640.95
38_L72_D0.8590.95
185_I191_I0.8590.95
40_A176_V0.8590.95
87_A90_E0.8530.95
227_T230_K0.8510.95
146_I153_L0.8500.95
103_A107_K0.8490.95
72_D76_R0.8470.95
117_E123_Y0.8460.95
210_S213_A0.8450.95
110_F137_L0.8430.95
231_H244_E0.8420.95
205_S208_D0.8390.95
119_S123_Y0.8380.95
98_A130_L0.8360.94
26_F61_G0.8300.94
49_T52_D0.8300.94
86_D204_A0.8260.94
43_A50_D0.8260.94
204_A211_Q0.8250.94
140_I166_I0.8240.94
5_T54_I0.8240.94
129_L141_N0.8200.94
244_E248_H0.8150.94
94_P130_L0.8130.94
115_F173_V0.8120.94
13_E32_K0.8090.93
105_I110_F0.8080.93
133_E139_V0.7990.93
82_Y108_I0.7980.93
105_I135_L0.7960.93
228_E231_H0.7950.93
103_A208_D0.7940.93
82_Y200_N0.7930.93
61_G83_L0.7890.93
117_E178_S0.7860.92
158_T179_D0.7810.92
210_S214_P0.7810.92
92_A96_D0.7730.92
108_I202_W0.7700.92
81_L199_V0.7630.91
104_A202_W0.7610.91
6_C101_L0.7580.91
76_R186_P0.7550.91
40_A114_I0.7530.91
147_Q156_E0.7510.91
36_F39_N0.7490.90
59_V84_V0.7480.90
218_L221_I0.7480.90
124_A216_A0.7470.90
46_Q184_R0.7430.90
139_V173_V0.7430.90
32_K120_G0.7420.90
33_I38_L0.7390.90
149_Q167_E0.7340.90
39_N177_T0.7310.89
202_W206_D0.7280.89
6_C105_I0.7220.89
71_K195_G0.7220.89
193_G197_K0.7130.88
11_P26_F0.7130.88
153_L174_L0.7120.88
104_A108_I0.7080.88
44_A114_I0.7050.88
194_A197_K0.7030.88
93_L96_D0.6940.87
117_E177_T0.6930.87
41_I56_A0.6930.87
57_L101_L0.6910.87
229_R232_I0.6900.87
217_E220_G0.6900.87
12_E32_K0.6900.87
106_E136_Q0.6850.86
192_L196_K0.6820.86
65_Q199_V0.6810.86
140_I153_L0.6810.86
131_V173_V0.6800.86
84_V207_I0.6770.85
105_I109_G0.6740.85
146_I174_L0.6740.85
119_S124_A0.6720.85
106_E109_G0.6710.85
95_L215_L0.6670.85
34_S120_G0.6600.84
31_A63_L0.6590.84
243_A247_E0.6580.84
157_R166_I0.6580.84
41_I45_S0.6570.84
94_P126_Q0.6530.83
46_Q49_T0.6510.83
86_D91_H0.6510.83
9_L31_A0.6510.83
75_S190_A0.6500.83
95_L134_I0.6500.83
5_T44_A0.6460.83
37_D122_L0.6440.83
3_I54_I0.6430.82
155_I172_A0.6420.82
41_I176_V0.6410.82
59_V92_A0.6400.82
59_V101_L0.6390.82
112_L153_L0.6380.82
120_G123_Y0.6380.82
33_I72_D0.6370.82
230_K233_I0.6350.82
70_R83_L0.6340.82
23_T218_L0.6330.81
42_E49_T0.6330.81
97_T122_L0.6290.81
93_L214_P0.6280.81
93_L216_A0.6280.81
94_P122_L0.6270.81
117_E142_A0.6230.80
59_V93_L0.6220.80
142_A177_T0.6190.80
92_A213_A0.6180.80
25_N29_A0.6170.80
37_D124_A0.6120.79
8_K58_T0.6120.79
57_L108_I0.6120.79
145_A165_V0.6080.79
158_T177_T0.6080.79
232_I244_E0.6070.79
105_I137_L0.6060.79
47_L112_L0.6060.79
11_P29_A0.6030.78
36_F123_Y0.6020.78
112_L174_L0.6010.78
129_L175_C0.6000.78
115_F128_G0.5990.78
5_T40_A0.5960.77
92_A214_P0.5960.77
159_L164_E0.5930.77
95_L128_G0.5930.77
138_P168_L0.5930.77
100_A104_A0.5910.77
132_G173_V0.5880.77
114_I146_I0.5870.76
26_F59_V0.5860.76
13_E35_Q0.5840.76
224_P245_L0.5840.76
105_I173_V0.5830.76
37_D69_V0.5820.76
188_M195_G0.5820.76
41_I73_V0.5780.75
12_E30_D0.5780.75
9_L63_L0.5770.75
110_F113_L0.5760.75
96_D213_A0.5750.75
61_G91_H0.5730.75
73_V78_P0.5730.75
19_T25_N0.5720.75
112_L170_V0.5710.74
106_E135_L0.5670.74
75_S194_A0.5660.74
70_R199_V0.5640.74
47_L114_I0.5610.73
9_L60_G0.5610.73
20_P25_N0.5600.73
2_K110_F0.5600.73
143_V146_I0.5600.73
228_E232_I0.5570.73
22_Y26_F0.5560.72
3_I6_C0.5560.72
23_T26_F0.5560.72
194_A224_P0.5540.72
210_S215_L0.5530.72
52_D111_D0.5520.72
92_A97_T0.5490.72
126_Q130_L0.5490.72
99_K209_W0.5470.71
39_N158_T0.5470.71
225_P229_R0.5460.71
30_D188_M0.5440.71
19_T23_T0.5430.71
144_S158_T0.5400.70
168_L174_L0.5380.70
35_Q123_Y0.5340.69
33_I41_I0.5330.69
118_G125_Q0.5320.69
45_S54_I0.5310.69
71_K198_P0.5300.69
182_V191_I0.5290.69
39_N178_S0.5270.68
107_K206_D0.5260.68
100_A211_Q0.5260.68
198_P247_E0.5210.68
117_E179_D0.5190.67
35_Q120_G0.5180.67
214_P218_L0.5170.67
86_D90_E0.5160.67
63_L68_K0.5150.67
45_S73_V0.5150.67
40_A116_G0.5140.67
76_R196_K0.5120.66
102_A134_I0.5100.66
118_G224_P0.5100.66
94_P124_A0.5100.66
58_T70_R0.5070.65
3_I114_I0.5040.65
71_K197_K0.5030.65
155_I165_V0.5020.65
123_Y139_V0.5020.65
35_Q117_E0.5000.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4l2iB 1 0.9882 100 0.198 Contact Map
1o97C 1 0.937 100 0.2 Contact Map
1efpB 1 0.9449 100 0.224 Contact Map
1efvB 1 0.9646 100 0.243 Contact Map
3ih5A 6 0.7756 100 0.614 Contact Map
4l2iA 1 0.8937 100 0.617 Contact Map
1o97D 1 0.8346 100 0.629 Contact Map
1efvA 1 0.8307 99.9 0.656 Contact Map
1efpA 1 0.811 99.9 0.659 Contact Map
3fetA 2 0.6417 99.9 0.683 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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