GREMLIN Database
YNHG - Probable L,D-transpeptidase YnhG
UniProt: P76193 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG14015
Length: 334 (292)
Sequences: 562 (344)
Seq/√Len: 20.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_A233_I5.3241.00
136_T184_A5.0431.00
140_Q182_R4.6021.00
104_E238_K4.1721.00
151_A155_Q3.8441.00
156_R207_S3.7661.00
128_G206_S3.7371.00
108_Y238_K3.2731.00
249_V288_V3.0510.99
148_T170_A2.9450.99
104_E108_Y2.9010.99
176_L191_L2.8640.99
123_G206_S2.7860.99
129_L207_S2.7050.98
120_Y219_A2.4920.97
56_R65_I2.4290.97
214_A218_K2.4260.97
88_L119_V2.3880.96
154_R166_P2.3570.96
146_T170_A2.2810.95
89_L240_S2.2120.95
157_S162_I2.1540.94
93_A110_Y2.0800.93
180_A217_I2.0600.92
150_T189_E2.0330.92
153_I207_S2.0130.91
15_F22_W1.9780.90
155_Q159_E1.9700.90
21_A36_V1.9140.89
138_V181_L1.9110.89
148_T167_V1.9110.89
56_R215_P1.9040.89
47_G77_K1.9000.89
241_V247_R1.8940.88
61_A200_S1.8650.88
182_R191_L1.8630.88
56_R198_P1.8340.87
65_I82_I1.8320.87
200_S205_V1.8060.86
152_G189_E1.7950.85
55_A65_I1.7900.85
122_I210_I1.7810.85
211_R238_K1.7800.85
249_V302_V1.7340.83
108_Y233_I1.7260.83
100_V210_I1.6770.81
250_E299_P1.6660.81
102_L183_L1.6540.80
144_N178_R1.6450.80
158_L163_K1.6290.79
35_L89_L1.5460.76
61_A73_A1.5430.75
52_Q213_N1.5420.75
25_D42_Y1.5390.75
150_T153_I1.5140.74
34_R240_S1.5070.74
180_A191_L1.4790.72
127_Q206_S1.4760.72
152_G207_S1.4730.72
123_G128_G1.4590.71
73_A199_D1.4370.70
126_L156_R1.4370.70
76_P79_G1.4260.69
48_D176_L1.4260.69
44_V78_P1.4150.69
192_I212_M1.4110.68
149_P154_R1.4070.68
120_Y191_L1.4060.68
129_L156_R1.3800.67
183_L190_Y1.3640.66
201_V205_V1.3630.66
249_V291_A1.3620.66
129_L134_M1.3520.65
283_V288_V1.3460.65
285_Q288_V1.3400.64
93_A235_E1.3320.64
75_V199_D1.3300.64
102_L232_V1.3260.64
30_P95_R1.3130.63
81_T110_Y1.3100.63
36_V103_A1.3030.62
135_E231_K1.2960.62
234_N255_L1.2720.60
135_E229_P1.2680.60
181_L218_K1.2660.60
202_G230_V1.2630.60
154_R164_L1.2590.59
56_R213_N1.2570.59
105_L206_S1.2560.59
237_V285_Q1.2470.59
144_N227_G1.2430.58
55_A213_N1.2330.58
72_I80_T1.2320.58
181_L248_Y1.2280.57
142_I226_T1.2270.57
35_L248_Y1.2270.57
36_V88_L1.2200.57
134_M185_H1.2190.57
141_K184_A1.2090.56
198_P201_V1.2090.56
95_R191_L1.1990.56
52_Q56_R1.1960.55
42_Y58_F1.1910.55
289_D292_L1.1890.55
74_P128_G1.1880.55
44_V47_G1.1830.55
11_L16_S1.1730.54
149_P238_K1.1680.54
157_S199_D1.1670.54
90_L201_V1.1650.53
41_T81_T1.1500.52
104_E211_R1.1450.52
178_R214_A1.1370.52
97_G117_V1.1330.51
107_L245_G1.1270.51
64_L203_L1.1140.50
24_V59_D1.1120.50
68_A85_P1.1030.49
125_G211_R1.0960.49
218_K222_S1.0930.49
241_V245_G1.0880.48
131_T210_I1.0870.48
44_V77_K1.0860.48
167_V170_A1.0810.48
107_L196_S1.0790.48
139_G184_A1.0690.47
47_G78_P1.0580.46
200_S203_L1.0560.46
124_I128_G1.0470.46
179_Y222_S1.0460.46
251_V291_A1.0460.46
183_L214_A1.0410.45
85_P106_R1.0400.45
9_L16_S1.0400.45
98_I224_V1.0390.45
40_Q86_S1.0320.45
158_L300_V1.0220.44
288_V302_V1.0220.44
17_A20_A1.0200.44
92_D235_E1.0170.44
99_I169_P1.0110.43
35_L87_Q1.0040.43
164_L299_P0.9970.43
67_E253_R0.9960.42
51_L65_I0.9940.42
291_A300_V0.9870.42
284_D290_K0.9850.42
61_A70_N0.9780.41
14_A18_I0.9720.41
72_I103_A0.9670.41
77_K80_T0.9660.41
71_T300_V0.9610.40
84_I221_F0.9610.40
16_S20_A0.9600.40
164_L205_V0.9570.40
26_Y36_V0.9570.40
125_G190_Y0.9500.40
137_R227_G0.9500.40
157_S163_K0.9490.39
54_I153_I0.9460.39
252_H299_P0.9450.39
98_I138_V0.9430.39
183_L191_L0.9410.39
26_Y29_P0.9400.39
131_T218_K0.9340.39
159_E167_V0.9310.38
105_L142_I0.9310.38
96_Q113_G0.9270.38
205_V299_P0.9260.38
149_P211_R0.9250.38
39_N122_I0.9230.38
29_P32_G0.9170.38
44_V79_G0.9110.37
20_A276_Q0.9110.37
125_G297_G0.9070.37
25_D283_V0.9070.37
290_K294_R0.9060.37
108_Y212_M0.9000.36
136_T255_L0.8960.36
250_E295_R0.8930.36
155_Q291_A0.8920.36
54_I201_V0.8910.36
139_G182_R0.8900.36
157_S197_A0.8900.36
276_Q302_V0.8830.35
47_G176_L0.8810.35
137_R226_T0.8810.35
238_K250_E0.8770.35
134_M198_P0.8710.35
10_T14_A0.8650.34
246_M301_S0.8640.34
63_M74_P0.8630.34
129_L189_E0.8620.34
44_V245_G0.8580.34
151_A166_P0.8520.34
74_P123_G0.8520.34
261_Q266_M0.8500.34
72_I76_P0.8430.33
19_Q201_V0.8430.33
201_V251_V0.8400.33
26_Y117_V0.8320.33
48_D54_I0.8320.33
28_L111_P0.8280.32
173_N218_K0.8240.32
113_G221_F0.8240.32
130_E196_S0.8180.32
94_P111_P0.8110.31
118_Q219_A0.8110.31
100_V232_V0.8090.31
134_M184_A0.8080.31
251_V292_L0.8050.31
252_H295_R0.7990.31
287_L291_A0.7980.31
149_P190_Y0.7950.30
131_T195_T0.7950.30
135_E227_G0.7880.30
86_S155_Q0.7810.30
64_L240_S0.7810.30
27_P30_P0.7800.30
225_R228_T0.7800.30
103_A123_G0.7790.30
234_N254_P0.7780.30
30_P143_P0.7750.29
100_V274_F0.7730.29
245_G256_S0.7710.29
179_Y218_K0.7700.29
240_S257_A0.7600.29
94_P155_Q0.7550.28
61_A106_R0.7550.28
143_P179_Y0.7520.28
84_I219_A0.7510.28
218_K255_L0.7510.28
183_L210_I0.7510.28
61_A85_P0.7470.28
54_I223_S0.7450.28
166_P284_D0.7420.28
201_V206_S0.7400.27
106_R202_G0.7380.27
50_N78_P0.7370.27
110_Y233_I0.7360.27
62_A139_G0.7340.27
160_R173_N0.7340.27
70_N200_S0.7320.27
273_G277_F0.7290.27
204_R234_N0.7290.27
142_I182_R0.7260.27
102_L144_N0.7260.27
120_Y262_N0.7240.27
191_L203_L0.7220.27
181_L221_F0.7220.27
155_Q283_V0.7210.27
32_G36_V0.7190.26
91_P174_N0.7130.26
204_R245_G0.7070.26
226_T284_D0.7060.26
72_I270_L0.7050.26
125_G217_I0.7030.26
250_E297_G0.7010.26
31_T110_Y0.7010.26
107_L204_R0.7000.25
45_Q48_D0.6980.25
28_L94_P0.6980.25
105_L182_R0.6970.25
62_A200_S0.6960.25
14_A17_A0.6940.25
12_I16_S0.6940.25
24_V283_V0.6910.25
251_V301_S0.6880.25
164_L250_E0.6880.25
31_T58_F0.6870.25
64_L302_V0.6850.25
76_P203_L0.6850.25
116_I226_T0.6830.25
152_G156_R0.6750.24
149_P212_M0.6740.24
29_P111_P0.6740.24
60_T159_E0.6730.24
105_L191_L0.6720.24
156_R205_V0.6690.24
126_L129_L0.6680.24
113_G138_V0.6660.24
95_R149_P0.6660.24
168_V232_V0.6640.24
68_A83_T0.6600.24
50_N126_L0.6580.23
241_V281_K0.6560.23
84_I179_Y0.6550.23
37_G85_P0.6540.23
105_L207_S0.6530.23
134_M191_L0.6510.23
104_E149_P0.6480.23
42_Y89_L0.6470.23
94_P302_V0.6470.23
157_S203_L0.6450.23
63_M102_L0.6440.23
237_V251_V0.6440.23
181_L217_I0.6400.23
268_Y271_P0.6370.22
64_L140_Q0.6350.22
16_S179_Y0.6350.22
11_L17_A0.6350.22
123_G194_G0.6350.22
43_T287_L0.6320.22
9_L276_Q0.6310.22
138_V144_N0.6310.22
72_I75_V0.6310.22
17_A21_A0.6280.22
16_S302_V0.6260.22
35_L80_T0.6260.22
183_L217_I0.6250.22
289_D293_Y0.6250.22
59_D283_V0.6230.22
60_T66_L0.6210.22
43_T144_N0.6210.22
25_D114_E0.6200.22
10_T18_I0.6200.22
56_R199_D0.6160.22
33_S103_A0.6150.22
166_P225_R0.6150.22
131_T198_P0.6070.21
31_T95_R0.6060.21
20_A57_R0.6050.21
206_S233_I0.6040.21
74_P84_I0.6040.21
29_P255_L0.6030.21
159_E188_G0.6030.21
121_P216_D0.6030.21
104_E200_S0.6010.21
154_R211_R0.6000.21
51_L122_I0.5990.21
27_P31_T0.5980.21
23_A29_P0.5980.21
115_N251_V0.5970.21
12_I20_A0.5970.21
104_E217_I0.5960.21
114_E249_V0.5950.21
134_M214_A0.5940.21
58_F302_V0.5930.21
167_V248_Y0.5930.21
41_T163_K0.5910.20
123_G127_Q0.5890.20
35_L44_V0.5880.20
52_Q199_D0.5880.20
141_K228_T0.5870.20
197_A205_V0.5860.20
172_P227_G0.5850.20
97_G190_Y0.5850.20
34_R95_R0.5850.20
62_A194_G0.5840.20
204_R255_L0.5840.20
152_G197_A0.5830.20
262_N265_T0.5830.20
62_A119_V0.5810.20
142_I184_A0.5800.20
137_R296_A0.5760.20
197_A295_R0.5750.20
70_N212_M0.5740.20
110_Y118_Q0.5690.20
158_L168_V0.5680.20
183_L194_G0.5640.19
12_I158_L0.5620.19
34_R66_L0.5620.19
33_S108_Y0.5620.19
64_L157_S0.5600.19
133_V235_E0.5590.19
62_A74_P0.5590.19
35_L240_S0.5590.19
104_E250_E0.5590.19
228_T245_G0.5570.19
51_L264_Q0.5570.19
176_L183_L0.5560.19
123_G224_V0.5560.19
69_N165_P0.5560.19
16_S43_T0.5560.19
179_Y217_I0.5550.19
61_A76_P0.5540.19
76_P85_P0.5540.19
84_I232_V0.5530.19
141_K236_P0.5490.19
157_S200_S0.5490.19
25_D32_G0.5480.19
169_P211_R0.5480.19
25_D46_E0.5480.19
63_M105_L0.5460.19
270_L275_T0.5430.19
9_L13_G0.5430.19
153_I253_R0.5420.18
16_S19_Q0.5420.18
85_P202_G0.5400.18
36_V58_F0.5400.18
155_Q222_S0.5400.18
122_I296_A0.5390.18
195_T214_A0.5390.18
263_V266_M0.5380.18
138_V260_Q0.5380.18
178_R225_R0.5370.18
60_T65_I0.5360.18
212_M288_V0.5340.18
181_L220_L0.5330.18
125_G183_L0.5330.18
131_T217_I0.5320.18
205_V251_V0.5310.18
36_V163_K0.5310.18
50_N298_Y0.5300.18
13_G272_A0.5290.18
121_P245_G0.5280.18
168_V211_R0.5270.18
264_Q269_T0.5270.18
144_N179_Y0.5270.18
88_L240_S0.5250.18
159_E275_T0.5240.18
14_A22_W0.5210.18
268_Y273_G0.5200.18
54_I144_N0.5190.18
103_A201_V0.5190.18
43_T270_L0.5170.18
74_P102_L0.5150.17
105_L204_R0.5150.17
68_A182_R0.5150.17
176_L297_G0.5150.17
189_E207_S0.5130.17
157_S164_L0.5110.17
194_G220_L0.5110.17
45_Q75_V0.5110.17
206_S256_S0.5110.17
146_T290_K0.5100.17
53_A162_I0.5080.17
140_Q189_E0.5080.17
171_G175_P0.5070.17
191_L207_S0.5060.17
252_H297_G0.5060.17
212_M217_I0.5040.17
11_L115_N0.5040.17
195_T221_F0.5030.17
74_P206_S0.5010.17
138_V164_L0.5010.17
141_K182_R0.5000.17
12_I19_Q0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lzhA 1 0.8174 100 0.432 Contact Map
4xvoA 1 0.5898 100 0.671 Contact Map
4jmnA 1 0.5868 100 0.684 Contact Map
4a1kA 2 0.494 100 0.689 Contact Map
4k73A 1 0.5629 100 0.749 Contact Map
3vypA 1 0.6856 100 0.758 Contact Map
1zatA 1 0.6257 100 0.763 Contact Map
4qtfA 2 0.7275 100 0.769 Contact Map
5bmqA 3 0.5569 100 0.775 Contact Map
4lpqA 1 0.5479 100 0.786 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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